Assay ID | Title | Year | Journal | Article |
AID359617 | Inhibition of bee venom PLA2 | 1992 | Journal of natural products, Dec, Volume: 55, Issue:12
| Phospholipase A2 inhibitors from marine organisms. |
AID462418 | Golgi-disturbing activity in golgi apparatus of rat NRK cells assessed as golgi fragmentation after 60 mins by Hoechst 3342 staining-based immunofluorescence microscopy | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
| Chemical biology studies on norrisolide. |
AID568751 | Cytotoxicity against human HT-29 cells after 48 hrs by SRB assay | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1
| Sesquiterpene benzoxazoles and sesquiterpene quinones from the marine sponge Dactylospongia elegans. |
AID1647967 | Antiproliferative activity against human PC3 cells assessed as reduction in cell viability by MTT assay | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2
| Quintaquinone, a Merosesquiterpene from the Yellow Sponge |
AID377195 | Inhibition of thymidine kinase at 1 ug/uL | 2000 | Journal of natural products, Aug, Volume: 63, Issue:8
| Pelorol from the tropical marine sponge Dactylospongia elegans. |
AID402134 | Cytotoxicity against human KB16 cells after 3 days by MTT assay | 1997 | Journal of natural products, Feb, Volume: 60, Issue:2
| New sesquiterpene hydroquinones from a Taiwanese marine sponge Polyfibrospongia australis. |
AID1439821 | Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated nitric oxide production at 40 uM by Griess assay relative to control | 2017 | Bioorganic & medicinal chemistry letters, 04-01, Volume: 27, Issue:7
| Sesquiterpene derivatives from marine sponge Smenospongia cerebriformis and their anti-inflammatory activity. |
AID333108 | Inhibition of human MDA-MB-231 cells invasion at <50 ug/mL by Matrigel cell invasion assay | 2004 | Journal of natural products, Aug, Volume: 67, Issue:8
| Strongylophorine-26, a new meroditerpenoid isolated from the marine sponge Petrosia (Strongylophora) corticata that exhibits anti-invasion activity. |
AID1467592 | Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by WST8 assay | 2017 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 27, Issue:14
| New merosesquiterpenes from a Vietnamese marine sponge of Spongia sp. and their biological activities. |
AID568752 | Cytotoxicity against human CHOK1 cells after 48 hrs by SRB assay | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1
| Sesquiterpene benzoxazoles and sesquiterpene quinones from the marine sponge Dactylospongia elegans. |
AID377196 | Antitrypanosomal activity against Trypanosoma rhodesiense | 2000 | Journal of natural products, Aug, Volume: 63, Issue:8
| Pelorol from the tropical marine sponge Dactylospongia elegans. |
AID1439822 | Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated nitric oxide production by Griess assay | 2017 | Bioorganic & medicinal chemistry letters, 04-01, Volume: 27, Issue:7
| Sesquiterpene derivatives from marine sponge Smenospongia cerebriformis and their anti-inflammatory activity. |
AID1178613 | Antiproliferative activity against human DU145 cells assessed as growth inhibition under hypoxic condition at 1 to 30 uM after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14
| Marine spongian sesquiterpene phenols, dictyoceratin-C and smenospondiol, display hypoxia-selective growth inhibition against cancer cells. |
AID1467595 | Antibacterial activity against Bacillus subtilis NBRC 13719 after 12 hrs by MTT assay | 2017 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 27, Issue:14
| New merosesquiterpenes from a Vietnamese marine sponge of Spongia sp. and their biological activities. |
AID1467596 | Antibacterial activity against Staphylococcus aureus NBRC 100910 after 12 hrs by MTT assay | 2017 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 27, Issue:14
| New merosesquiterpenes from a Vietnamese marine sponge of Spongia sp. and their biological activities. |
AID477475 | Inhibition of S-adenosyl-L-homocysteine hydrolase after 10 mins by scintillation counting | 2009 | Bioorganic & medicinal chemistry, Sep-15, Volume: 17, Issue:18
| A new structural class of S-adenosylhomocysteine hydrolase inhibitors. |
AID462413 | Golgi-disturbing activity in golgi apparatus of rat NRK cells assessed as complete golgi vesiculation without fusion with endoplasmic reticulum at 30 uM after 60 mins by Hoechst 3342 staining-based immunofluorescence microscopy | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
| Chemical biology studies on norrisolide. |
AID751051 | Cytotoxicity against human T47D cells assessed as growth inhibition at 3 to 30 uM after 48 hrs by SRB assay | 2013 | Journal of natural products, Jun-28, Volume: 76, Issue:6
| Inducers of hypoxic response: marine sesquiterpene quinones activate HIF-1. |
AID1467593 | Antibacterial activity against Escherichia coli NBRC 102203 after 12 hrs by MTT assay | 2017 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 27, Issue:14
| New merosesquiterpenes from a Vietnamese marine sponge of Spongia sp. and their biological activities. |
AID568750 | Cytotoxicity against human H460 cells after 48 hrs by SRB assay | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1
| Sesquiterpene benzoxazoles and sesquiterpene quinones from the marine sponge Dactylospongia elegans. |
AID328641 | Antidepressant like activity in ip dosed Swiss Webster mouse assessed as reduction of immobility time by forced-swim test | 2008 | Journal of natural products, Feb, Volume: 71, Issue:2
| Secondary metabolites from three Florida sponges with antidepressant activity. |
AID333393 | Inhibition of GST-fused human recombinant Cdc25B2 (275-539) catalytic domain | 2004 | Journal of natural products, Oct, Volume: 67, Issue:10
| Marine sesquiterpenoids that inhibit the lyase activity of DNA polymerase beta. |
AID333392 | Inhibition of DNA polymerase beta lyase activity | 2004 | Journal of natural products, Oct, Volume: 67, Issue:10
| Marine sesquiterpenoids that inhibit the lyase activity of DNA polymerase beta. |
AID1647966 | Inhibition of steroid 5-alpha-reductase in human LNCAP cells assessed as reduction in 5- dihydrotestosterone formation at 100 uM incubated for 60 mins by LC-MS analysis relative to control | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2
| Quintaquinone, a Merosesquiterpene from the Yellow Sponge |
AID568748 | Cytotoxicity against human SF268 cells after 48 hrs by SRB assay | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1
| Sesquiterpene benzoxazoles and sesquiterpene quinones from the marine sponge Dactylospongia elegans. |
AID1467590 | Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by WST8 assay | 2017 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 27, Issue:14
| New merosesquiterpenes from a Vietnamese marine sponge of Spongia sp. and their biological activities. |
AID1467589 | Cytotoxicity against human WI38 cells assessed as decrease in cell viability after 72 hrs by WST8 assay | 2017 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 27, Issue:14
| New merosesquiterpenes from a Vietnamese marine sponge of Spongia sp. and their biological activities. |
AID751056 | Activation of HIF-1 (unknown origin) transfected in human T47D cells at 10 uM after 16 hrs by luciferase reporter gene assay relative to control | 2013 | Journal of natural products, Jun-28, Volume: 76, Issue:6
| Inducers of hypoxic response: marine sesquiterpene quinones activate HIF-1. |
AID377198 | Antiplasmodial activity against Plasmodium falciparum NF54 | 2000 | Journal of natural products, Aug, Volume: 63, Issue:8
| Pelorol from the tropical marine sponge Dactylospongia elegans. |
AID1647968 | Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by sulforhodamine B assay | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2
| Quintaquinone, a Merosesquiterpene from the Yellow Sponge |
AID402133 | Cytotoxicity against mouse P388 cells after 3 days by MTT assay | 1997 | Journal of natural products, Feb, Volume: 60, Issue:2
| New sesquiterpene hydroquinones from a Taiwanese marine sponge Polyfibrospongia australis. |
AID402135 | Cytotoxicity against human A549 cells after 6 days by MTT assay | 1997 | Journal of natural products, Feb, Volume: 60, Issue:2
| New sesquiterpene hydroquinones from a Taiwanese marine sponge Polyfibrospongia australis. |
AID1439823 | Cytotoxicity against mouse BV2 cells assessed as cell viability at 40 uM relative to control | 2017 | Bioorganic & medicinal chemistry letters, 04-01, Volume: 27, Issue:7
| Sesquiterpene derivatives from marine sponge Smenospongia cerebriformis and their anti-inflammatory activity. |
AID751052 | Cytotoxicity against human T47D cells assessed as growth inhibition at 30 uM after 48 hrs by SRB assay relative to control | 2013 | Journal of natural products, Jun-28, Volume: 76, Issue:6
| Inducers of hypoxic response: marine sesquiterpene quinones activate HIF-1. |
AID1647969 | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by sulforhodamine B assay | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2
| Quintaquinone, a Merosesquiterpene from the Yellow Sponge |
AID751053 | Activation of HIF-1 in human T47D cells assessed as increase in cellular VEGF production at 10 uM after 16 hrs by ELISA | 2013 | Journal of natural products, Jun-28, Volume: 76, Issue:6
| Inducers of hypoxic response: marine sesquiterpene quinones activate HIF-1. |
AID377197 | Antiplasmodial activity against Plasmodium falciparum K1 | 2000 | Journal of natural products, Aug, Volume: 63, Issue:8
| Pelorol from the tropical marine sponge Dactylospongia elegans. |
AID568749 | Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1
| Sesquiterpene benzoxazoles and sesquiterpene quinones from the marine sponge Dactylospongia elegans. |
AID751049 | Activation of HIF-1 in human PC3 cells assessed as increase in VEGF production at 10 uM after 16 hrs by ELISA | 2013 | Journal of natural products, Jun-28, Volume: 76, Issue:6
| Inducers of hypoxic response: marine sesquiterpene quinones activate HIF-1. |
AID462416 | Golgi-disturbing activity in golgi apparatus of rat NRK cells assessed as golgi fragmentation after 60 mins by Hoechst 3342 staining-based immunofluorescence microscopy in presence of PKD inhibitor H89 | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
| Chemical biology studies on norrisolide. |
AID1467591 | Cytotoxicity against human A549 cells assessed as decrease in cell viability after 72 hrs by WST8 assay | 2017 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 27, Issue:14
| New merosesquiterpenes from a Vietnamese marine sponge of Spongia sp. and their biological activities. |
AID751050 | Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition at 3 to 30 uM after 48 hrs by SRB assay | 2013 | Journal of natural products, Jun-28, Volume: 76, Issue:6
| Inducers of hypoxic response: marine sesquiterpene quinones activate HIF-1. |
AID333394 | Cytotoxicity against human A2780 cells | 2004 | Journal of natural products, Oct, Volume: 67, Issue:10
| Marine sesquiterpenoids that inhibit the lyase activity of DNA polymerase beta. |
AID1467594 | Antibacterial activity against Klebsiella pneumoniae NBRC 14940 after 12 hrs by MTT assay | 2017 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 27, Issue:14
| New merosesquiterpenes from a Vietnamese marine sponge of Spongia sp. and their biological activities. |
AID462417 | Golgi-disturbing activity in golgi apparatus of rat NRK cells assessed as irreversible golgi fragmentation after 60 mins by Hoechst 3342 staining-based immunofluorescence microscopy | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6
| Chemical biology studies on norrisolide. |
AID751054 | Activation of HIF-1 in human T47D cells assessed as increase in secreted VEGF production at 10 uM after 16 hrs by ELISA | 2013 | Journal of natural products, Jun-28, Volume: 76, Issue:6
| Inducers of hypoxic response: marine sesquiterpene quinones activate HIF-1. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |