Page last updated: 2024-12-06

sodium aluminum hydride

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Sodium aluminum hydride (NaAlH4) is a white, crystalline compound that is a powerful reducing agent. It is used in organic chemistry to reduce carbonyl compounds, such as aldehydes and ketones, to alcohols. Sodium aluminum hydride is also used to reduce esters, amides, and nitriles. The compound is also used in the production of pharmaceuticals, polymers, and other chemicals. Sodium aluminum hydride is synthesized by reacting sodium hydride (NaH) with aluminum chloride (AlCl3) in a solvent, such as diethyl ether. The reaction is exothermic and must be carefully controlled. Sodium aluminum hydride is a highly reactive compound and must be handled with care. It is a strong reducing agent and can react violently with water, acids, and oxidizing agents. Sodium aluminum hydride is an important compound because of its ability to reduce a wide range of functional groups. It is also used in the synthesis of a variety of important chemicals. Research is ongoing to develop new and more efficient methods for the synthesis of sodium aluminum hydride. Sodium aluminum hydride is also being studied for its potential use in hydrogen storage. Hydrogen is a promising energy source, but it is difficult to store and transport. Sodium aluminum hydride can potentially be used to store hydrogen in a solid form, which would make it easier to transport and use.'

Cross-References

ID SourceID
PubMed CID26266
CHEBI ID30141
MeSH IDM0501967

Synonyms (17)

Synonym
aluminate(1-), tetrahydro-, sodium, (t-4)-
sodium aluminum hydride
CHEBI:30141
na[alh4]
sodium tetrahydroaluminate
aluminum sodium hydride
13770-96-2
sodium tetrahydridoaluminate
sodium aluminum tetrahydride
sodium tetrahydroaluminate(1-)
sodium aluminum hydride, hydrogen-storage grade
sodium aluminum hydride, technical grade, 90%
sodium aluminium hydride
naalh4
aluminum(iii) sodium hydride
sodium;alumanuide
Q1961048
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
inorganic sodium salt
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (23)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (30.43)29.6817
2010's13 (56.52)24.3611
2020's3 (13.04)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 44.34

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index44.34 (24.57)
Research Supply Index3.22 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index62.63 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (44.34)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (4.35%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other22 (95.65%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]