A cytochrome P450 2B10 that is encoded in the genome of rat. [OMA:P00176, PRO:DNx]
EC 1.14.14.1;
CYPIIB1;
Cytochrome P450-B;
Cytochrome P450b;
Cytochrome P450-LM2;
Cytochrome P450-PB1;
Cytochrome P450-PB2
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 5,6-dimethylbenzimidazole | Rattus norvegicus (Norway rat) | IC50 | 180.9850 | 2 | 2 |
| benzyl isothiocyanate | Rattus norvegicus (Norway rat) | Ki | 5.8000 | 1 | 1 |
| clorgyline | Rattus norvegicus (Norway rat) | Ki | 1.5000 | 1 | 1 |
| thiotepa | Rattus norvegicus (Norway rat) | Ki | 31.0000 | 1 | 1 |
| 2-hydroxybenzylbenzimidazole | Rattus norvegicus (Norway rat) | IC50 | 158.4890 | 1 | 1 |
| benzimidazole | Rattus norvegicus (Norway rat) | IC50 | 978.6185 | 2 | 2 |
| ethinyl estradiol | Rattus norvegicus (Norway rat) | Ki | 11.0000 | 1 | 1 |
| 5-methylbenzimidazole | Rattus norvegicus (Norway rat) | IC50 | 575.4400 | 1 | 1 |
| 2-methylbenzimidazole | Rattus norvegicus (Norway rat) | IC50 | 1,075.7600 | 2 | 2 |
| bendazole | Rattus norvegicus (Norway rat) | IC50 | 91.2011 | 1 | 1 |
| 2-phenylbenzimidazole | Rattus norvegicus (Norway rat) | IC50 | 54.9541 | 1 | 1 |
| n-methylcarbazole | Rattus norvegicus (Norway rat) | Ki | 5.2000 | 1 | 1 |
| 2-ethylbenzimidazole | Rattus norvegicus (Norway rat) | IC50 | 673.0415 | 2 | 2 |
| 2-Butyl-1H-benzimidazole | Rattus norvegicus (Norway rat) | IC50 | 120.2260 | 1 | 1 |
| selegiline | Rattus norvegicus (Norway rat) | Ki | 1.0500 | 1 | 1 |
| 2-tert-butylbenzimidazole | Rattus norvegicus (Norway rat) | IC50 | 301.9950 | 1 | 1 |
| proadifen hydrochloride | Rattus norvegicus (Norway rat) | IC50 | 8.2000 | 1 | 1 |
| 4(5)-phenylimidazole | Rattus norvegicus (Norway rat) | IC50 | 7.4000 | 1 | 1 |
| 2-(2'-pyridyl)benzimidazole | Rattus norvegicus (Norway rat) | IC50 | 64.5654 | 1 | 1 |
| 2-ethynylnaphthalene | Rattus norvegicus (Norway rat) | Ki | 0.0800 | 1 | 1 |
| 9-ethynylphenanthrene | Rattus norvegicus (Norway rat) | Ki | 0.1400 | 1 | 1 |
| atorvastatin calcium | Rattus norvegicus (Norway rat) | Ki | 12.0000 | 1 | 1 |
| 5,6-dichlorobenzimidazole | Rattus norvegicus (Norway rat) | IC50 | 81.2831 | 1 | 1 |
| bergamottin | Rattus norvegicus (Norway rat) | Ki | 2.4000 | 1 | 1 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 5,6-dimethylbenzimidazole | Rattus norvegicus (Norway rat) | Ks | 62.0000 | 1 | 1 |
| acetaminophen | Rattus norvegicus (Norway rat) | Ks | 800.0000 | 1 | 1 |
| benzimidazole | Rattus norvegicus (Norway rat) | Ks | 110.0000 | 1 | 1 |
| 5-methylbenzimidazole | Rattus norvegicus (Norway rat) | Ks | 62.0000 | 1 | 1 |
| 2-methylbenzimidazole | Rattus norvegicus (Norway rat) | Ks | 440.0000 | 1 | 1 |
| 4(5)-phenylimidazole | Rattus norvegicus (Norway rat) | Ks | 1.1000 | 1 | 1 |