Condition | Indicated | Relationship Strength | Studies | Trials |
Cancer of Esophagus [description not available] | 0 | 3 | 4 | 0 |
Alcohol Drinking Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking. | 0 | 8.73 | 30 | 4 |
Esophageal Neoplasms Tumors or cancer of the ESOPHAGUS. | 0 | 3 | 4 | 0 |
Morbid Obesity [description not available] | 0 | 5.49 | 5 | 1 |
Obesity, Morbid The condition of weighing two, three, or more times the ideal weight, so called because it is associated with many serious and life-threatening disorders. In the BODY MASS INDEX, morbid obesity is defined as having a BMI greater than 40.0 kg/m2. | 0 | 5.49 | 5 | 1 |
Infections, Salmonella [description not available] | 0 | 2.31 | 1 | 0 |
Hypophosphatasia A genetic metabolic disorder resulting from serum and bone alkaline phosphatase deficiency leading to hypercalcemia, ethanolamine phosphatemia, and ethanolamine phosphaturia. Clinical manifestations include severe skeletal defects resembling vitamin D-resistant rickets, failure of the calvarium to calcify, dyspnea, cyanosis, vomiting, constipation, renal calcinosis, failure to thrive, disorders of movement, beading of the costochondral junction, and rachitic bone changes. (From Dorland, 27th ed) | 0 | 7.7 | 17 | 1 |
Benign Neoplasms [description not available] | 0 | 13.34 | 49 | 5 |
Cardiovascular Diseases Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM. | 0 | 18.76 | 132 | 38 |
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 13.34 | 49 | 5 |
Deficiency, Pyridoxine [description not available] | 0 | 17.12 | 251 | 10 |
2019 Novel Coronavirus Disease [description not available] | 0 | 5.48 | 6 | 0 |
Cardiac Diseases [description not available] | 0 | 4.47 | 9 | 0 |
Diabetes Mellitus A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE. | 0 | 10.65 | 17 | 5 |
Heart Diseases Pathological conditions involving the HEART including its structural and functional abnormalities. | 0 | 4.47 | 9 | 0 |
Carcinogenesis The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years. | 0 | 3.6 | 3 | 0 |
Colorectal Cancer [description not available] | 0 | 11.98 | 54 | 5 |
Obesity A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY). | 0 | 7.85 | 22 | 2 |
Colorectal Neoplasms Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI. | 0 | 11.98 | 54 | 5 |
Cognitive Decline [description not available] | 0 | 9.29 | 21 | 5 |
Atrophy Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes. | 0 | 4.87 | 7 | 1 |
Cognitive Dysfunction Diminished or impaired mental and/or intellectual function. | 0 | 9.29 | 21 | 5 |
Age-Related Osteoporosis [description not available] | 0 | 4.07 | 5 | 0 |
Bimalleolar Ankle Fractures [description not available] | 0 | 2.31 | 1 | 0 |
Osteoporosis Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. | 0 | 4.07 | 5 | 0 |
Ankle Fractures Fractures of any of the bones of the ANKLE. | 0 | 2.31 | 1 | 0 |
Hypomania [description not available] | 0 | 3.7 | 1 | 1 |
Affective Psychosis, Bipolar [description not available] | 0 | 4.93 | 3 | 2 |
Bipolar Disorder A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence. | 0 | 4.93 | 3 | 2 |
Anoxemia [description not available] | 0 | 2.9 | 3 | 0 |
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 8.39 | 50 | 0 |
Arterial Diseases, Cerebral [description not available] | 0 | 2.48 | 2 | 0 |
Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms. | 0 | 2.9 | 3 | 0 |
Cerebral Arterial Diseases Pathological conditions of intracranial ARTERIES supplying the CEREBRUM. These diseases often are due to abnormalities or pathological processes in the ANTERIOR CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY; and POSTERIOR CEREBRAL ARTERY. | 0 | 2.48 | 2 | 0 |
Cirrhosis [description not available] | 0 | 2.31 | 1 | 0 |
Graft-Versus-Host Disease [description not available] | 0 | 2.31 | 1 | 0 |
Leucocythaemia [description not available] | 0 | 3.19 | 6 | 0 |
Germinoblastoma [description not available] | 0 | 2.94 | 4 | 0 |
Fibrosis Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury. | 0 | 2.31 | 1 | 0 |
Graft vs Host Disease The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION. | 0 | 2.31 | 1 | 0 |
Leukemia A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) | 0 | 3.19 | 6 | 0 |
Lymphoma A general term for various neoplastic diseases of the lymphoid tissue. | 0 | 2.94 | 4 | 0 |
Anoxia-Ischemia, Brain [description not available] | 0 | 2.31 | 1 | 0 |
Acquired Metabolic Diseases, Brain [description not available] | 0 | 2.31 | 1 | 0 |
Aura [description not available] | 0 | 8.42 | 43 | 1 |
Diseases, Metabolic [description not available] | 0 | 3.24 | 6 | 0 |
Absence Seizure [description not available] | 0 | 7.35 | 50 | 0 |
Epilepsy A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313) | 0 | 8.42 | 43 | 1 |
Metabolic Diseases Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed) | 0 | 3.24 | 6 | 0 |
Seizures Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder. | 0 | 7.35 | 50 | 0 |
Hypoxia-Ischemia, Brain A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions. | 0 | 2.31 | 1 | 0 |
Hyperhomocysteinemia Condition in which the plasma levels of homocysteine and related metabolites are elevated ( | 0 | 19.12 | 186 | 45 |
Deficiency, Folic Acid [description not available] | 0 | 10.15 | 27 | 2 |
Bowel Diseases, Inflammatory [description not available] | 0 | 5.28 | 7 | 0 |
Anemia A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN. | 0 | 7.4 | 33 | 0 |
Folic Acid Deficiency A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed) | 0 | 10.15 | 27 | 2 |
Inflammatory Bowel Diseases Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS. | 0 | 5.28 | 7 | 0 |
Peripheral Nerve Diseases [description not available] | 0 | 6.35 | 17 | 0 |
Polyneuropathy, Acquired [description not available] | 0 | 4.69 | 10 | 0 |
Peripheral Nervous System Diseases Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves. | 0 | 6.35 | 17 | 0 |
Polyneuropathies Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance. | 0 | 4.69 | 10 | 0 |
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 4.15 | 15 | 0 |
Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. | 0 | 11.95 | 39 | 7 |
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 20.24 | 187 | 13 |
Anemias, Iron-Deficiency [description not available] | 0 | 5.51 | 5 | 0 |
Preterm Birth [description not available] | 0 | 4.46 | 6 | 0 |
Complications, Pregnancy [description not available] | 0 | 12.62 | 55 | 6 |
HIV Coinfection [description not available] | 0 | 6.78 | 8 | 1 |
Complications, Infectious Pregnancy [description not available] | 0 | 3.23 | 1 | 0 |
HIV Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2. | 0 | 3.23 | 1 | 0 |
HIV Infections Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS). | 0 | 6.78 | 8 | 1 |
Anemia, Iron-Deficiency Anemia characterized by decreased or absent iron stores, low serum iron concentration, low transferrin saturation, and low hemoglobin concentration or hematocrit value. The erythrocytes are hypochromic and microcytic and the iron binding capacity is increased. | 0 | 5.51 | 5 | 0 |
Premature Birth CHILDBIRTH before 37 weeks of PREGNANCY (259 days from the first day of the mother's last menstrual period, or 245 days after FERTILIZATION). | 0 | 4.46 | 6 | 0 |
Anxiety Neuroses [description not available] | 0 | 5.31 | 4 | 1 |
Chronic Motor and Vocal Tic Disorder [description not available] | 0 | 6.19 | 4 | 3 |
Anxiety Disorders Persistent and disabling ANXIETY. | 0 | 5.31 | 4 | 1 |
Tourette Syndrome A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79) | 0 | 6.19 | 4 | 3 |
Malnourishment [description not available] | 0 | 4.41 | 4 | 1 |
Malnutrition An imbalanced nutritional status resulting from insufficient intake of nutrients to meet normal physiological requirement. | 0 | 4.41 | 4 | 1 |
Gyrate Atrophy Progressive, autosomal recessive, diffuse atrophy of the choroid, pigment epithelium, and sensory retina that begins in childhood. | 0 | 4.56 | 8 | 0 |
Adenocarcinoma Of Kidney [description not available] | 0 | 4.14 | 5 | 0 |
Cancer of Kidney [description not available] | 0 | 4.29 | 6 | 0 |
Carcinoma, Renal Cell A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma. | 0 | 4.14 | 5 | 0 |
Kidney Neoplasms Tumors or cancers of the KIDNEY. | 0 | 4.29 | 6 | 0 |
Acute Kidney Failure [description not available] | 0 | 2.38 | 2 | 0 |
Critical Illness A disease or state in which death is possible or imminent. | 0 | 5.75 | 7 | 1 |
Acute Kidney Injury Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | 0 | 2.38 | 2 | 0 |
Local Neoplasm Recurrence [description not available] | 0 | 4.14 | 3 | 1 |
Job Stress [description not available] | 0 | 2.41 | 1 | 0 |
Behavior Disorders [description not available] | 0 | 4.98 | 9 | 0 |
Mental Disorders Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function. | 0 | 4.98 | 9 | 0 |
Cardiac Failure [description not available] | 0 | 6.45 | 12 | 0 |
Innate Inflammatory Response [description not available] | 0 | 13.71 | 51 | 6 |
Cardiovascular Stroke [description not available] | 0 | 15.41 | 49 | 21 |
Heart Failure A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION. | 0 | 6.45 | 12 | 0 |
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. | 0 | 13.71 | 51 | 6 |
Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). | 0 | 15.41 | 49 | 21 |
Cancer of Lung [description not available] | 0 | 5.51 | 14 | 0 |
Lung Neoplasms Tumors or cancer of the LUNG. | 0 | 5.51 | 14 | 0 |
Idiopathic Parkinson Disease [description not available] | 0 | 8.3 | 26 | 1 |
Absence Status [description not available] | 0 | 2.98 | 4 | 0 |
Parkinson Disease A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) | 0 | 8.3 | 26 | 1 |
Status Epilepticus A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30) | 0 | 2.98 | 4 | 0 |
Chronic Illness [description not available] | 0 | 9.19 | 16 | 2 |
Itching [description not available] | 0 | 3.79 | 3 | 0 |
Dermatoses [description not available] | 0 | 3.22 | 6 | 0 |
Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). | 0 | 9.19 | 16 | 2 |
Pruritus An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief. | 0 | 3.79 | 3 | 0 |
Skin Diseases Diseases involving the DERMIS or EPIDERMIS. | 0 | 3.22 | 6 | 0 |
Colitis, Mucous [description not available] | 0 | 2.54 | 2 | 0 |
Colicky Pain [description not available] | 0 | 2.41 | 1 | 0 |
Abdominal Pain Sensation of discomfort, distress, or agony in the abdominal region. | 0 | 2.41 | 1 | 0 |
Irritable Bowel Syndrome A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION. | 0 | 2.54 | 2 | 0 |
Dysmyelopoietic Syndromes [description not available] | 0 | 2.57 | 2 | 0 |
Myelodysplastic Syndromes Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA. | 0 | 2.57 | 2 | 0 |
Hyperglycemia, Postprandial Abnormally high BLOOD GLUCOSE level after a meal. | 0 | 3.12 | 4 | 0 |
Insulin Sensitivity [description not available] | 0 | 4.1 | 5 | 0 |
Hyperglycemia Abnormally high BLOOD GLUCOSE level. | 0 | 3.12 | 4 | 0 |
Insulin Resistance Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS. | 0 | 4.1 | 5 | 0 |
Verruca [description not available] | 0 | 2.41 | 1 | 0 |
Warts Benign epidermal proliferations or tumors; some are viral in origin. | 0 | 2.41 | 1 | 0 |
Lassitude [description not available] | 0 | 4.25 | 6 | 0 |
Fatigue The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. | 0 | 4.25 | 6 | 0 |
Hyperprolactinaemia [description not available] | 0 | 3.33 | 1 | 0 |
Hyperprolactinemia Increased levels of PROLACTIN in the BLOOD, which may be associated with AMENORRHEA and GALACTORRHEA. Relatively common etiologies include PROLACTINOMA, medication effect, KIDNEY FAILURE, granulomatous diseases of the PITUITARY GLAND, and disorders which interfere with the hypothalamic inhibition of prolactin release. Ectopic (non-pituitary) production of prolactin may also occur. (From Joynt, Clinical Neurology, 1992, Ch36, pp77-8) | 0 | 3.33 | 1 | 0 |
Breast Cancer [description not available] | 0 | 11.42 | 32 | 4 |
Breast Neoplasms Tumors or cancer of the human BREAST. | 0 | 11.42 | 32 | 4 |
Diffuse Myofascial Pain Syndrome [description not available] | 0 | 3.8 | 1 | 1 |
Ache [description not available] | 0 | 5.98 | 3 | 3 |
Fibromyalgia A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95) | 0 | 3.8 | 1 | 1 |
Pain An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS. | 0 | 5.98 | 3 | 3 |
Adverse Drug Event [description not available] | 0 | 6.07 | 5 | 1 |
Drug-Related Side Effects and Adverse Reactions Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals. | 0 | 6.07 | 5 | 1 |
Anxiety Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS. | 0 | 6.43 | 9 | 1 |
Cancer of the Thyroid [description not available] | 0 | 2.41 | 1 | 0 |
Thyroid Neoplasms Tumors or cancer of the THYROID GLAND. | 0 | 2.41 | 1 | 0 |
Diabetes Mellitus, Adult-Onset [description not available] | 0 | 9.24 | 19 | 4 |
Diabetes Mellitus, Type 2 A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY. | 0 | 9.24 | 19 | 4 |
Hepatic Porphyria [description not available] | 0 | 2.41 | 1 | 0 |
Porphyrias, Hepatic A group of metabolic diseases due to deficiency of one of a number of LIVER enzymes in the biosynthetic pathway of HEME. They are characterized by the accumulation and increased excretion of PORPHYRINS or its precursors. Clinical features include neurological symptoms (PORPHYRIA, ACUTE INTERMITTENT), cutaneous lesions due to photosensitivity (PORPHYRIA CUTANEA TARDA), or both (HEREDITARY COPROPORPHYRIA). Hepatic porphyrias can be hereditary or acquired as a result of toxicity to the hepatic tissues. | 0 | 2.41 | 1 | 0 |
Acute Confusional Senile Dementia [description not available] | 0 | 13.14 | 35 | 7 |
Alzheimer Disease A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) | 0 | 13.14 | 35 | 7 |
Neuroblastoma A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51) | 0 | 2.41 | 1 | 0 |
Postpartum Amenorrhea [description not available] | 0 | 2.41 | 1 | 0 |
Amenorrhea Absence of menstruation. | 0 | 2.41 | 1 | 0 |
Apoplexy [description not available] | 0 | 16.57 | 64 | 27 |
Stroke A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810) | 0 | 16.57 | 64 | 27 |
Erythema Migrans, Lingual [description not available] | 0 | 2.41 | 1 | 0 |
Aphthae [description not available] | 0 | 4.08 | 3 | 1 |
Deficiency, Vitamin A [description not available] | 0 | 2.66 | 2 | 0 |
Cheilitis Inflammation of the lips. It is of various etiologies and degrees of pathology. | 0 | 2.69 | 2 | 0 |
Stomatitis, Aphthous A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval. Two to eight crops of lesions occur per year, lasting for 7 to 14 days and then heal without scarring. (From Jablonski's Dictionary of Dentistry, 1992, p742) | 0 | 4.08 | 3 | 1 |
Vitamin A Deficiency A nutritional condition produced by a deficiency of VITAMIN A in the diet, characterized by NIGHT BLINDNESS and other ocular manifestations such as dryness of the conjunctiva and later of the cornea (XEROPHTHALMIA). Vitamin A deficiency is a very common problem worldwide, particularly in developing countries as a consequence of famine or shortages of vitamin A-rich foods. In the United States it is found among the urban poor, the elderly, alcoholics, and patients with malabsorption. (From Cecil Textbook of Medicine, 19th ed, p1179) | 0 | 2.66 | 2 | 0 |
Dementia Praecox [description not available] | 0 | 9.6 | 16 | 5 |
Schizophrenia A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior. | 0 | 9.6 | 16 | 5 |
Deficiency, Riboflavin [description not available] | 0 | 6.32 | 5 | 1 |
Edema-Proteinuria-Hypertension Gestosis [description not available] | 0 | 4.98 | 9 | 0 |
Pre-Eclampsia A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease. | 0 | 4.98 | 9 | 0 |
Pain, Chronic [description not available] | 0 | 4.96 | 5 | 1 |
Chronic Pain Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain. | 0 | 4.96 | 5 | 1 |
Diabetes Mellitus, Gestational [description not available] | 0 | 4.73 | 8 | 0 |
Diabetes, Gestational Diabetes mellitus induced by PREGNANCY but resolved at the end of pregnancy. It does not include previously diagnosed diabetics who become pregnant (PREGNANCY IN DIABETICS). Gestational diabetes usually develops in late pregnancy when insulin antagonistic hormones peaks leading to INSULIN RESISTANCE; GLUCOSE INTOLERANCE; and HYPERGLYCEMIA. | 0 | 4.73 | 8 | 0 |
Cerebral Pseudosclerosis [description not available] | 0 | 3.69 | 8 | 0 |
Hepatolenticular Degeneration A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years. | 0 | 3.69 | 8 | 0 |
Muscle Spasm [description not available] | 0 | 2.38 | 2 | 0 |
Cryptogenic Infantile Spasms [description not available] | 0 | 8.39 | 15 | 2 |
Spasm An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE. | 0 | 2.38 | 2 | 0 |
Spasms, Infantile An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8) | 0 | 8.39 | 15 | 2 |
Restless Leg Syndrome [description not available] | 0 | 3.9 | 2 | 1 |
Restless Legs Syndrome A disorder characterized by aching or burning sensations in the lower and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep. | 0 | 3.9 | 2 | 1 |
Cardiometabolic Syndrome A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components not only include metabolic dysfunctions of METABOLIC SYNDROME but also HYPERTENSION, and ABDOMINAL OBESITY. | 0 | 3.96 | 4 | 0 |
Metabolic Syndrome A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. | 0 | 3.96 | 4 | 0 |
Emesis [description not available] | 0 | 11.85 | 63 | 8 |
Nausea An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses. | 0 | 11.27 | 34 | 8 |
Vomiting The forcible expulsion of the contents of the STOMACH through the MOUTH. | 0 | 11.85 | 63 | 8 |
Airflow Obstruction, Chronic [description not available] | 0 | 2.53 | 2 | 0 |
Debility [description not available] | 0 | 2.72 | 2 | 0 |
Pulmonary Disease, Chronic Obstructive A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA. | 0 | 2.53 | 2 | 0 |
Deafness, Transitory [description not available] | 0 | 2.66 | 2 | 0 |
Long Sleeper Syndrome [description not available] | 0 | 5.52 | 5 | 1 |
Day Blindness [description not available] | 0 | 3.28 | 5 | 0 |
Sleep Wake Disorders Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle. | 0 | 5.52 | 5 | 1 |
Hearing Loss A general term for the complete or partial loss of the ability to hear from one or both ears. | 0 | 2.66 | 2 | 0 |
Cancer of Gastrointestinal Tract [description not available] | 0 | 2.6 | 1 | 0 |
Cancer of Colon [description not available] | 0 | 5.7 | 13 | 0 |
Colonic Neoplasms Tumors or cancer of the COLON. | 0 | 5.7 | 13 | 0 |
Blood Pressure, High [description not available] | 0 | 9.05 | 15 | 3 |
Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. | 0 | 9.05 | 15 | 3 |
Kidney Diseases Pathological processes of the KIDNEY or its component tissues. | 0 | 7 | 11 | 1 |
Birth Weight The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms. | 0 | 4.87 | 7 | 0 |
Deficiency, Vitamin B 12 [description not available] | 0 | 14.41 | 42 | 12 |
Vitamin B 12 Deficiency A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. (From Cecil Textbook of Medicine, 19th ed, p848) | 0 | 14.41 | 42 | 12 |
Disease Resistance The capacity of an organism to defend itself against pathological processes or the agents of those processes. This most often involves innate immunity whereby the organism responds to pathogens in a generic way. The term disease resistance is used most frequently when referring to plants. | 0 | 2.9 | 3 | 0 |
Abnormalities, Autosome [description not available] | 0 | 3.36 | 6 | 0 |
Asthma, Bronchial [description not available] | 0 | 2.65 | 3 | 0 |
Asthma A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL). | 0 | 2.65 | 3 | 0 |
Carcinoma, Non-Small Cell Lung [description not available] | 0 | 5.51 | 5 | 1 |
Carcinoma, Non-Small-Cell Lung A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy. | 0 | 5.51 | 5 | 1 |
Cholangiitis, Sclerosing [description not available] | 0 | 2.6 | 1 | 0 |
Cholangitis, Sclerosing Chronic inflammatory disease of the BILIARY TRACT. It is characterized by fibrosis and hardening of the intrahepatic and extrahepatic biliary ductal systems leading to bile duct strictures, CHOLESTASIS, and eventual BILIARY CIRRHOSIS. | 0 | 2.6 | 1 | 0 |
Age-Related Macular Degeneration [description not available] | 0 | 4.24 | 3 | 1 |
Macular Degeneration Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms. | 0 | 4.24 | 3 | 1 |
Cancer of Pancreas [description not available] | 0 | 6.22 | 13 | 0 |
Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA). | 0 | 6.22 | 13 | 0 |
Colitis Gravis [description not available] | 0 | 2.49 | 2 | 0 |
Colitis, Granulomatous [description not available] | 0 | 2.75 | 3 | 0 |
Colitis, Ulcerative Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN. | 0 | 2.49 | 2 | 0 |
Crohn Disease A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients. | 0 | 2.75 | 3 | 0 |
Experimental Lung Inflammation Inflammation of any part, segment or lobe, of the lung parenchyma. | 0 | 2.76 | 2 | 0 |
Pneumonia Infection of the lung often accompanied by inflammation. | 0 | 2.76 | 2 | 0 |
Impaired Glucose Tolerance [description not available] | 0 | 3.7 | 3 | 0 |
Glucose Intolerance A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION. | 0 | 3.7 | 3 | 0 |
Acrania [description not available] | 0 | 6.93 | 11 | 1 |
Neural Tube Defects Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41) | 0 | 6.93 | 11 | 1 |
Alcohol Related Neurodevelopmental Disorder [description not available] | 0 | 2.6 | 1 | 0 |
Delayed Effects, Prenatal Exposure [description not available] | 0 | 3.34 | 6 | 0 |
Abdominal Obesity [description not available] | 0 | 2.6 | 1 | 0 |
Adult-Onset Dystonias [description not available] | 0 | 2.6 | 1 | 0 |
Dystonia An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77) | 0 | 2.6 | 1 | 0 |
CBS Deficiency [description not available] | 0 | 5.31 | 12 | 0 |
Homocystinuria Autosomal recessive inborn error of methionine metabolism usually caused by a deficiency of CYSTATHIONINE BETA-SYNTHASE and associated with elevations of homocysteine in plasma and urine. Clinical features include a tall slender habitus, SCOLIOSIS, arachnodactyly, MUSCLE WEAKNESS, genu varus, thin blond hair, malar flush, lens dislocations, an increased incidence of MENTAL RETARDATION, and a tendency to develop fibrosis of arteries, frequently complicated by CEREBROVASCULAR ACCIDENTS and MYOCARDIAL INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, p979) | 0 | 5.31 | 12 | 0 |
Dystonic Disorders Acquired and inherited conditions that feature DYSTONIA as a primary manifestation of disease. These disorders are generally divided into generalized dystonias (e.g., dystonia musculorum deformans) and focal dystonias (e.g., writer's cramp). They are also classified by patterns of inheritance and by age of onset. | 0 | 2.6 | 1 | 0 |
Menopause The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age. | 0 | 4.06 | 5 | 0 |
Hypothermia, Accidental [description not available] | 0 | 2.6 | 1 | 0 |
Hypothermia Lower than normal body temperature, especially in warm-blooded animals. | 0 | 2.6 | 1 | 0 |
Cancer of Stomach [description not available] | 0 | 4.26 | 6 | 0 |
Cachexia General ill health, malnutrition, and weight loss, usually associated with chronic disease. | 0 | 2.6 | 1 | 0 |
Stomach Neoplasms Tumors or cancer of the STOMACH. | 0 | 4.26 | 6 | 0 |
Fatty Liver, Nonalcoholic [description not available] | 0 | 3.08 | 4 | 0 |
Non-alcoholic Fatty Liver Disease Fatty liver finding without excessive ALCOHOL CONSUMPTION. | 0 | 3.08 | 4 | 0 |
Recrudescence [description not available] | 0 | 8.25 | 11 | 4 |
Astrocytoma, Grade IV [description not available] | 0 | 3.73 | 3 | 0 |
Glioblastoma A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 0 | 3.73 | 3 | 0 |
Genome Instability [description not available] | 0 | 2.89 | 3 | 0 |
Alarm Clock Headache [description not available] | 0 | 3.64 | 1 | 1 |
Gastritis Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders. | 0 | 2.38 | 2 | 0 |
Diarrhea An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight. | 0 | 3.27 | 5 | 0 |
Osteoarthritis of Knee [description not available] | 0 | 2.21 | 1 | 0 |
Arthritis, Degenerative [description not available] | 0 | 2.21 | 1 | 0 |
Osteoarthritis A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. | 0 | 2.21 | 1 | 0 |
Osteoarthritis, Knee Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019) | 0 | 2.21 | 1 | 0 |
Ambulation Disorders, Neurologic [description not available] | 0 | 2.5 | 2 | 0 |
Encephalopathy, Toxic [description not available] | 0 | 2.78 | 3 | 0 |
Nutritional Disorders [description not available] | 0 | 2.25 | 1 | 0 |
Nutrition Disorders Disorders caused by nutritional imbalance, either overnutrition or undernutrition. | 0 | 2.25 | 1 | 0 |
Drug Overdose Accidental or deliberate use of a medication or street drug in excess of normal dosage. | 0 | 3.31 | 6 | 0 |
Blood Poisoning [description not available] | 0 | 2.57 | 2 | 0 |
Sepsis Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK. | 0 | 2.57 | 2 | 0 |
Anovulation Suspension or cessation of OVULATION in animals or humans with follicle-containing ovaries (OVARIAN FOLLICLE). Depending on the etiology, OVULATION may be induced with appropriate therapy. | 0 | 2.25 | 1 | 0 |
Polycystic Ovarian Syndrome [description not available] | 0 | 2.25 | 1 | 0 |
Polycystic Ovary Syndrome A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading. | 0 | 2.25 | 1 | 0 |
Depression Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders. | 0 | 10.88 | 34 | 7 |
Motor Disorders Motor skills deficits that significantly and persistently interfere with ACTIVITIES OF DAILY LIVING appropriate to chronological age. (from DSM-5) | 0 | 2.21 | 1 | 0 |
Deficiency, Mental [description not available] | 0 | 3.34 | 7 | 0 |
Intellectual Disability Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28) | 0 | 3.34 | 7 | 0 |
Chronic Fatigue and Immune Dysfunction Syndrome [description not available] | 0 | 2.25 | 1 | 0 |
Fatigue Syndrome, Chronic A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9) | 0 | 2.25 | 1 | 0 |
Acute Myelogenous Leukemia [description not available] | 0 | 5.35 | 6 | 0 |
Leukemia, Myeloid, Acute Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES. | 0 | 5.35 | 6 | 0 |
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 5.39 | 13 | 0 |
Brain Disorders [description not available] | 0 | 2.69 | 3 | 0 |
Brain Diseases Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM. | 0 | 2.69 | 3 | 0 |
Palmoplantaris Pustulosis [description not available] | 0 | 2.68 | 3 | 0 |
Psoriasis A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis. | 0 | 2.68 | 3 | 0 |
Astheno Teratozoospermia [description not available] | 0 | 2.25 | 1 | 0 |
Convulsions, Grand Mal [description not available] | 0 | 2.52 | 2 | 0 |
Epilepsy, Tonic-Clonic A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329) | 0 | 2.52 | 2 | 0 |
Adrenal Gland Hypofunction [description not available] | 0 | 3.17 | 1 | 0 |
Lymphocytopenia [description not available] | 0 | 3.4 | 2 | 0 |
Symptom Cluster [description not available] | 0 | 6.68 | 8 | 1 |
Adrenal Insufficiency Conditions in which the production of adrenal CORTICOSTEROIDS falls below the requirement of the body. Adrenal insufficiency can be caused by defects in the ADRENAL GLANDS, the PITUITARY GLAND, or the HYPOTHALAMUS. | 0 | 3.17 | 1 | 0 |
Lymphopenia Reduction in the number of lymphocytes. | 0 | 3.4 | 2 | 0 |
Nephrosis Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA. | 0 | 3.17 | 1 | 0 |
Syndrome A characteristic symptom complex. | 0 | 6.68 | 8 | 1 |
Experimental Hepatoma [description not available] | 0 | 2.65 | 3 | 0 |
Hepatocellular Carcinoma [description not available] | 0 | 5.97 | 9 | 1 |
Cancer of Liver [description not available] | 0 | 6.67 | 12 | 1 |
Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. | 0 | 5.97 | 9 | 1 |
Liver Neoplasms Tumors or cancer of the LIVER. | 0 | 6.67 | 12 | 1 |
Chronic Kidney Diseases [description not available] | 0 | 5.69 | 10 | 0 |
Chronic Kidney Failure [description not available] | 0 | 11.95 | 32 | 6 |
Kidney Failure, Chronic The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION. | 0 | 11.95 | 32 | 6 |
Uremia A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms. | 0 | 4.64 | 6 | 0 |
Renal Insufficiency, Chronic Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002) | 0 | 5.69 | 10 | 0 |
Deficiency, Magnesium [description not available] | 0 | 3.84 | 11 | 0 |
Magnesium Deficiency A nutritional condition produced by a deficiency of magnesium in the diet, characterized by anorexia, nausea, vomiting, lethargy, and weakness. Symptoms are paresthesias, muscle cramps, irritability, decreased attention span, and mental confusion, possibly requiring months to appear. Deficiency of body magnesium can exist even when serum values are normal. In addition, magnesium deficiency may be organ-selective, since certain tissues become deficient before others. (Harrison's Principles of Internal Medicine, 12th ed, p1936) | 0 | 3.84 | 11 | 0 |
Devic Disease [description not available] | 0 | 2.25 | 1 | 0 |
Neuromyelitis Optica A syndrome characterized by acute OPTIC NEURITIS; MYELITIS, TRANSVERSE; demyelinating and/or necrotizing lesions in the OPTIC NERVES and SPINAL CORD; and presence of specific autoantibodies to AQUAPORIN 4. | 0 | 2.25 | 1 | 0 |
Injuries, Radiation [description not available] | 0 | 4.99 | 16 | 0 |
Overweight A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat. | 0 | 6.12 | 6 | 1 |
Anorectal Anomalies [description not available] | 0 | 2.25 | 1 | 0 |
Optic Atrophy Atrophy of the optic disk which may be congenital or acquired. This condition indicates a deficiency in the number of nerve fibers which arise in the RETINA and converge to form the OPTIC DISK; OPTIC NERVE; OPTIC CHIASM; and optic tracts. GLAUCOMA; ISCHEMIA; inflammation, a chronic elevation of intracranial pressure, toxins, optic nerve compression, and inherited conditions (see OPTIC ATROPHIES, HEREDITARY) are relatively common causes of this condition. | 0 | 2.25 | 1 | 0 |
Cirrhosis, Liver [description not available] | 0 | 4.71 | 7 | 1 |
Liver Cirrhosis Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules. | 0 | 4.71 | 7 | 1 |
Acute Liver Injury, Drug-Induced [description not available] | 0 | 3.18 | 5 | 0 |
Chemical and Drug Induced Liver Injury A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. | 0 | 3.18 | 5 | 0 |
Acute Relapsing Multiple Sclerosis [description not available] | 0 | 2.25 | 1 | 0 |
Multiple Sclerosis, Relapsing-Remitting The most common clinical variant of MULTIPLE SCLEROSIS, characterized by recurrent acute exacerbations of neurologic dysfunction followed by partial or complete recovery. Common clinical manifestations include loss of visual (see OPTIC NEURITIS), motor, sensory, or bladder function. Acute episodes of demyelination may occur at any site in the central nervous system, and commonly involve the optic nerves, spinal cord, brain stem, and cerebellum. (Adams et al., Principles of Neurology, 6th ed, pp903-914) | 0 | 2.25 | 1 | 0 |
Latent Tuberculosis The dormant form of TUBERCULOSIS where the person shows no obvious symptoms and no sign of the causative agent (Mycobacterium tuberculosis) in the SPUTUM despite being positive for tuberculosis infection skin test. | 0 | 2.31 | 1 | 0 |
Exanthem [description not available] | 0 | 2.66 | 2 | 0 |
Cholera Infantum [description not available] | 0 | 3.08 | 5 | 0 |
Exanthema Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology. | 0 | 2.66 | 2 | 0 |
Cancer of Head [description not available] | 0 | 2.25 | 1 | 0 |
Weight Reduction [description not available] | 0 | 6.38 | 5 | 3 |
Head and Neck Neoplasms Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651) | 0 | 2.25 | 1 | 0 |
Weight Loss Decrease in existing BODY WEIGHT. | 0 | 6.38 | 5 | 3 |
Avitaminosis A condition due to a deficiency of one or more essential vitamins. (Dorland, 27th ed) | 0 | 6.95 | 21 | 0 |
Allergy, Drug [description not available] | 0 | 2.51 | 2 | 0 |
Bone Stress Reaction [description not available] | 0 | 2.25 | 1 | 0 |
Drug Hypersensitivity Immunologically mediated adverse reactions to medicinal substances used legally or illegally. | 0 | 2.51 | 2 | 0 |
Acne [description not available] | 0 | 3.17 | 1 | 0 |
Acne Vulgaris A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors. | 0 | 3.17 | 1 | 0 |
Disease Exacerbation [description not available] | 0 | 12.81 | 29 | 10 |
Allergic Encephalomyelitis [description not available] | 0 | 2.38 | 2 | 0 |
Circulatory Collapse [description not available] | 0 | 2.25 | 1 | 0 |
Shock A pathological condition manifested by failure to perfuse or oxygenate vital organs. | 0 | 2.25 | 1 | 0 |
Angiogenesis, Pathologic [description not available] | 0 | 3.39 | 2 | 0 |
Autosomal Dominant Striatonigral Degeneration [description not available] | 0 | 2.31 | 1 | 0 |
Machado-Joseph Disease A dominantly-inherited ATAXIA first described in people of Azorean and Portuguese descent, and subsequently identified in Brazil, Japan, China, and Australia. This disorder is classified as one of the SPINOCEREBELLAR ATAXIAS (Type 3) and has been associated with a mutation of the MJD1 gene on chromosome 14. Clinical features include progressive ataxia, DYSARTHRIA, postural instability, nystagmus, eyelid retraction, and facial FASCICULATIONS. DYSTONIA is prominent in younger patients (referred to as Type I Machado-Joseph Disease). Type II features ataxia and ocular signs; Type III features MUSCULAR ATROPHY and a sensorimotor neuropathy; and Type IV features extrapyramidal signs combined with a sensorimotor neuropathy. (From Clin Neurosci 1995;3(1):17-22; Ann Neurol 1998 Mar;43(3):288-96) | 0 | 2.31 | 1 | 0 |
Dysplastic Nevus Syndrome, Hereditary [description not available] | 0 | 2.31 | 1 | 0 |
Malignant Melanoma [description not available] | 0 | 2.48 | 2 | 0 |
Cancer of Skin [description not available] | 0 | 2.97 | 4 | 0 |
Melanoma A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) | 0 | 2.48 | 2 | 0 |
Skin Neoplasms Tumors or cancer of the SKIN. | 0 | 2.97 | 4 | 0 |
Genetic Predisposition [description not available] | 0 | 10.9 | 35 | 7 |
Addison's Anemia [description not available] | 0 | 2.31 | 1 | 0 |
Cancer of Digestive System [description not available] | 0 | 2.31 | 1 | 0 |
Deficiency, Vitamin B [description not available] | 0 | 11.51 | 45 | 4 |
Digestive System Neoplasms Tumors or cancer of the DIGESTIVE SYSTEM. | 0 | 2.31 | 1 | 0 |
Vitamin B Deficiency A condition due to deficiency in any member of the VITAMIN B COMPLEX. These B vitamins are water-soluble and must be obtained from the diet because they are easily lost in the urine. Unlike the lipid-soluble vitamins, they cannot be stored in the body fat. | 0 | 11.51 | 45 | 4 |
Nasopharyngeal Carcinoma A carcinoma that originates in the EPITHELIUM of the NASOPHARYNX and includes four subtypes: keratinizing squamous cell, non-keratinizing, basaloid squamous cell, and PAPILLARY ADENOCARCINOMA. It is most prevalent in Southeast Asian populations and is associated with EPSTEIN-BARR VIRUS INFECTIONS. Somatic mutations associated with this cancer have been identified in NPCR, BAP1, UBAP1, ERBB2, ERBB3, MLL2, PIK3CA, KRAS, NRAS, and ARID1A genes. | 0 | 2.59 | 2 | 0 |
Cancer of Nasopharynx [description not available] | 0 | 2.59 | 2 | 0 |
Nasopharyngeal Neoplasms Tumors or cancer of the NASOPHARYNX. | 0 | 2.59 | 2 | 0 |
Porphyria [description not available] | 0 | 3.23 | 1 | 0 |
Porphyrias A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues. | 0 | 3.23 | 1 | 0 |
Amentia [description not available] | 0 | 9.92 | 17 | 3 |
Dementia An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness. | 0 | 9.92 | 17 | 3 |
Abortion, Recurrent [description not available] | 0 | 3.71 | 3 | 0 |
Fetal Growth Restriction [description not available] | 0 | 3.47 | 2 | 0 |
Abortion, Habitual Three or more consecutive spontaneous abortions. | 0 | 3.71 | 3 | 0 |
Fetal Growth Retardation Failure of a FETUS to attain expected GROWTH. | 0 | 3.47 | 2 | 0 |
Diathesis [description not available] | 0 | 2.31 | 1 | 0 |
Infections, Plasmodium [description not available] | 0 | 4.81 | 5 | 0 |
Malaria A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia. | 0 | 4.81 | 5 | 0 |
Hyperlipemia [description not available] | 0 | 6.15 | 6 | 2 |
Hyperlipidemias Conditions with excess LIPIDS in the blood. | 0 | 6.15 | 6 | 2 |
Disease, Pulmonary [description not available] | 0 | 2.15 | 1 | 0 |
Lung Diseases Pathological processes involving any part of the LUNG. | 0 | 2.15 | 1 | 0 |
Burning Mouth Syndrome A group of painful oral symptoms associated with a burning or similar sensation. There is usually a significant organic component with a degree of functional overlay; it is not limited to the psychophysiologic group of disorders. | 0 | 3.43 | 2 | 0 |
Abnormality, Heart [description not available] | 0 | 2.47 | 2 | 0 |
Heart Defects, Congenital Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life. | 0 | 2.47 | 2 | 0 |
Drug Refractory Epilepsy [description not available] | 0 | 3.47 | 2 | 0 |
Benign Infantile Myoclonic Epilepsy [description not available] | 0 | 3.5 | 2 | 0 |
Adenoma Sebaceum Facial ANGIOFIBROMA in tuberous sclerosis | 0 | 3.91 | 2 | 0 |
Agenesis of Corpus Callosum with Chorioretinal Abnormality [description not available] | 0 | 3.06 | 1 | 0 |
Epilepsies, Myoclonic A clinically diverse group of epilepsy syndromes characterized either by myoclonic seizures or by myoclonus in association with other seizure types. Myoclonic epilepsy syndromes are divided into three subtypes based on etiology: familial, cryptogenic, and symptomatic. | 0 | 3.5 | 2 | 0 |
Tuberous Sclerosis Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease. | 0 | 3.91 | 2 | 0 |
Ambulation Difficulty [description not available] | 0 | 2.17 | 1 | 0 |
Morning Sickness Symptoms of NAUSEA and VOMITING in pregnant women that usually occur in the morning during the first 2 to 3 months of PREGNANCY. Severe persistent vomiting during pregnancy is called HYPEREMESIS GRAVIDARUM. | 0 | 8.72 | 9 | 2 |
Kidney Stones [description not available] | 0 | 3.11 | 5 | 0 |
Kidney Calculi Stones in the KIDNEY, usually formed in the urine-collecting area of the kidney (KIDNEY PELVIS). Their sizes vary and most contains CALCIUM OXALATE. | 0 | 3.11 | 5 | 0 |
Cognition Disorders Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment. | 0 | 14.37 | 42 | 12 |
Angor Pectoris [description not available] | 0 | 3.65 | 3 | 0 |
Angina Pectoris The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION. | 0 | 3.65 | 3 | 0 |
Acute Onset Vascular Dementia [description not available] | 0 | 6.39 | 8 | 0 |
Dementia, Vascular An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44) | 0 | 6.39 | 8 | 0 |
Muscle Contraction A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. | 0 | 3.56 | 1 | 1 |
Salmonella Infections, Animal Infections in animals with bacteria of the genus SALMONELLA. | 0 | 2.57 | 2 | 0 |
Oxaluria, Primary [description not available] | 0 | 9.03 | 8 | 4 |
Hyperoxaluria, Primary A genetic disorder characterized by excretion of large amounts of OXALATES in urine; NEPHROLITHIASIS; NEPHROCALCINOSIS; early onset of RENAL FAILURE; and often a generalized deposit of CALCIUM OXALATE. There are subtypes classified by the enzyme defects in glyoxylate metabolism. | 0 | 9.03 | 8 | 4 |
Hypomenorrhea [description not available] | 0 | 3.85 | 2 | 1 |
Vascular Calcification Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS. | 0 | 3.56 | 1 | 1 |
Arteriosclerosis, Coronary [description not available] | 0 | 12.45 | 27 | 15 |
Coronary Artery Disease Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause. | 0 | 12.45 | 27 | 15 |
Experimental Pneumococcal Meningitis [description not available] | 0 | 3.03 | 4 | 0 |
Meningitis, Pneumococcal An acute purulent infection of the meninges and subarachnoid space caused by Streptococcus pneumoniae, most prevalent in children and adults over the age of 60. This illness may be associated with OTITIS MEDIA; MASTOIDITIS; SINUSITIS; RESPIRATORY TRACT INFECTIONS; sickle cell disease (ANEMIA, SICKLE CELL); skull fractures; and other disorders. Clinical manifestations include FEVER; HEADACHE; neck stiffness; and somnolence followed by SEIZURES; focal neurologic deficits (notably DEAFNESS); and COMA. (From Miller et al., Merritt's Textbook of Neurology, 9th ed, p111) | 0 | 3.03 | 4 | 0 |
Carcinoma, Epidermoid [description not available] | 0 | 2.77 | 3 | 0 |
Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) | 0 | 2.77 | 3 | 0 |
Patent Foramen Ovale [description not available] | 0 | 2.55 | 2 | 0 |
Abdominal Migraine [description not available] | 0 | 6.63 | 8 | 1 |
Migraine Disorders A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1) | 0 | 6.63 | 8 | 1 |
Foramen Ovale, Patent A condition in which the FORAMEN OVALE in the ATRIAL SEPTUM fails to close shortly after birth. This results in abnormal communications between the two upper chambers of the heart. An isolated patent ovale foramen without other structural heart defects is usually of no hemodynamic significance. | 0 | 2.55 | 2 | 0 |
Liver Steatosis [description not available] | 0 | 2.54 | 2 | 0 |
Fatty Liver Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS. | 0 | 2.54 | 2 | 0 |
CACH Syndrome [description not available] | 0 | 5.1 | 3 | 1 |
BH4 Deficiency [description not available] | 0 | 3.23 | 6 | 0 |
Phenylketonurias A group of autosomal recessive disorders marked by a deficiency of the hepatic enzyme PHENYLALANINE HYDROXYLASE or less frequently by reduced activity of DIHYDROPTERIDINE REDUCTASE (i.e., atypical phenylketonuria). Classical phenylketonuria is caused by a severe deficiency of phenylalanine hydroxylase and presents in infancy with developmental delay; SEIZURES; skin HYPOPIGMENTATION; ECZEMA; and demyelination in the central nervous system. (From Adams et al., Principles of Neurology, 6th ed, p952). | 0 | 3.23 | 6 | 0 |
Autosomal Hemophilia A [description not available] | 0 | 2.52 | 2 | 0 |
Bleeding [description not available] | 0 | 2.68 | 3 | 0 |
Hemophilia A The classic hemophilia resulting from a deficiency of factor VIII. It is an inherited disorder of blood coagulation characterized by a permanent tendency to hemorrhage. | 0 | 2.52 | 2 | 0 |
Hemorrhage Bleeding or escape of blood from a vessel. | 0 | 2.68 | 3 | 0 |
Libman-Sacks Disease [description not available] | 0 | 2.79 | 3 | 0 |
Lupus Erythematosus, Systemic A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. | 0 | 2.79 | 3 | 0 |
Central Retinal Edema, Cystoid [description not available] | 0 | 2.17 | 1 | 0 |
Macular Edema Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90) | 0 | 2.17 | 1 | 0 |
Carcinoma, Small Cell Lung [description not available] | 0 | 2.17 | 1 | 0 |
Small Cell Lung Carcinoma A form of highly malignant lung cancer that is composed of small ovoid cells (SMALL CELL CARCINOMA). | 0 | 2.17 | 1 | 0 |
Autism [description not available] | 0 | 8.65 | 11 | 2 |
Autistic Disorder A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V) | 0 | 8.65 | 11 | 2 |
Benign Neoplasms, Brain [description not available] | 0 | 4.12 | 5 | 0 |
Brain Neoplasms Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 4.12 | 5 | 0 |
Elevated ICP (Intracranial Pressure) [description not available] | 0 | 2.17 | 1 | 0 |
Choked Disk [description not available] | 0 | 2.17 | 1 | 0 |
Benign Intracranial Hypertension [description not available] | 0 | 2.17 | 1 | 0 |
Deficiency, Vitamin D [description not available] | 0 | 4.38 | 4 | 0 |
Papilledema Swelling of the OPTIC DISK, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause OPTIC ATROPHY and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175) | 0 | 2.17 | 1 | 0 |
Pseudotumor Cerebri A condition marked by raised intracranial pressure and characterized clinically by HEADACHES; NAUSEA; PAPILLEDEMA, peripheral constriction of the visual fields, transient visual obscurations, and pulsatile TINNITUS. OBESITY is frequently associated with this condition, which primarily affects women between 20 and 44 years of age. Chronic PAPILLEDEMA may lead to optic nerve injury (see OPTIC NERVE DISEASES) and visual loss (see BLINDNESS). | 0 | 2.17 | 1 | 0 |
Vitamin D Deficiency A nutritional condition produced by a deficiency of VITAMIN D in the diet, insufficient production of vitamin D in the skin, inadequate absorption of vitamin D from the diet, or abnormal conversion of vitamin D to its bioactive metabolites. It is manifested clinically as RICKETS in children and OSTEOMALACIA in adults. (From Cecil Textbook of Medicine, 19th ed, p1406) | 0 | 4.38 | 4 | 0 |
Intracranial Hypertension Increased pressure within the cranial vault. This may result from several conditions, including HYDROCEPHALUS; BRAIN EDEMA; intracranial masses; severe systemic HYPERTENSION; PSEUDOTUMOR CEREBRI; and other disorders. | 0 | 2.17 | 1 | 0 |
Weight Gain Increase in BODY WEIGHT over existing weight. | 0 | 7.05 | 10 | 2 |
Alloxan Diabetes [description not available] | 0 | 4.16 | 6 | 0 |
Degenerative Diseases, Central Nervous System [description not available] | 0 | 4.17 | 3 | 0 |
Age-Related Memory Disorders [description not available] | 0 | 4.83 | 4 | 0 |
Memory Disorders Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions. | 0 | 4.83 | 4 | 0 |
Neurodegenerative Diseases Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures. | 0 | 4.17 | 3 | 0 |
Nervous System Disorders [description not available] | 0 | 3.46 | 8 | 0 |
Nervous System Diseases Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle. | 0 | 3.46 | 8 | 0 |
Pernicious Vomiting of Pregnancy [description not available] | 0 | 7.16 | 20 | 2 |
Hyperemesis Gravidarum Intractable VOMITING that develops in early PREGNANCY and persists. This can lead to DEHYDRATION and WEIGHT LOSS. | 0 | 7.16 | 20 | 2 |
Rheumatoid Arthritis [description not available] | 0 | 8.44 | 14 | 4 |
Herpes Simplex Virus Infection [description not available] | 0 | 2.17 | 1 | 0 |
Opportunistic Infections An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression. | 0 | 2.17 | 1 | 0 |
Sore Throat [description not available] | 0 | 2.17 | 1 | 0 |
Travel Sickness [description not available] | 0 | 2.17 | 1 | 0 |
Tuberculosis, Miliary An acute form of TUBERCULOSIS in which minute tubercles are formed in a number of organs of the body due to dissemination of the bacilli through the blood stream. | 0 | 2.17 | 1 | 0 |
Arthritis, Rheumatoid A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. | 0 | 8.44 | 14 | 4 |
Herpes Simplex A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.) | 0 | 2.17 | 1 | 0 |
Pharyngitis Inflammation of the throat (PHARYNX). | 0 | 2.17 | 1 | 0 |
Autism Spectrum Disorder Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V) | 0 | 5.16 | 3 | 1 |
Child Development Deviations [description not available] | 0 | 3.85 | 2 | 1 |
Food Poisoning [description not available] | 0 | 3.53 | 2 | 0 |
Developmental Disabilities Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed) | 0 | 3.85 | 2 | 1 |
Hyperoxaluria Excretion of an excessive amount of OXALATES in the urine. | 0 | 6.23 | 7 | 1 |
Complication, Postoperative [description not available] | 0 | 4.07 | 5 | 0 |
Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. | 0 | 4.07 | 5 | 0 |
Acute Bacterial Prostatitis [description not available] | 0 | 4.48 | 2 | 2 |
Prostatitis Infiltration of inflammatory cells into the parenchyma of PROSTATE. The subtypes are classified by their varied laboratory analysis, clinical presentation and response to treatment. | 0 | 4.48 | 2 | 2 |
Bladder Cancer [description not available] | 0 | 2.65 | 3 | 0 |
Urinary Bladder Neoplasms Tumors or cancer of the URINARY BLADDER. | 0 | 2.65 | 3 | 0 |
Carcinoma, Transitional Cell A malignant neoplasm derived from TRANSITIONAL EPITHELIAL CELLS, occurring chiefly in the URINARY BLADDER; URETERS; or RENAL PELVIS. | 0 | 2.21 | 1 | 0 |
Depression, Endogenous [description not available] | 0 | 4.37 | 4 | 0 |
Depressive Disorder An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent. | 0 | 4.37 | 4 | 0 |
Psychoses [description not available] | 0 | 6.73 | 6 | 4 |
Psychotic Disorders Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994) | 0 | 6.73 | 6 | 4 |
Convulsions, Febrile [description not available] | 0 | 2.21 | 1 | 0 |
Seizures, Febrile Seizures that occur during a febrile episode. It is a common condition, affecting 2-5% of children aged 3 months to five years. An autosomal dominant pattern of inheritance has been identified in some families. The majority are simple febrile seizures (generally defined as generalized onset, single seizures with a duration of less than 30 minutes). Complex febrile seizures are characterized by focal onset, duration greater than 30 minutes, and/or more than one seizure in a 24 hour period. The likelihood of developing epilepsy (i.e., a nonfebrile seizure disorder) following simple febrile seizures is low. Complex febrile seizures are associated with a moderately increased incidence of epilepsy. (From Menkes, Textbook of Child Neurology, 5th ed, p784) | 0 | 2.21 | 1 | 0 |
Adenocarcinoma, Basal Cell [description not available] | 0 | 3.68 | 10 | 0 |
Experimental Neoplasms [description not available] | 0 | 3.56 | 9 | 0 |
Adenocarcinoma A malignant epithelial tumor with a glandular organization. | 0 | 3.68 | 10 | 0 |
Angina Pectoris, Stable [description not available] | 0 | 8 | 5 | 5 |
Angina, Stable Persistent and reproducible chest discomfort usually precipitated by a physical exertion that dissipates upon cessation of such an activity. The symptoms are manifestations of MYOCARDIAL ISCHEMIA. | 0 | 8 | 5 | 5 |
Disbacteriosis [description not available] | 0 | 10.01 | 10 | 9 |
Colonic Inertia Symptom characterized by the passage of stool once a week or less. | 0 | 9.99 | 10 | 10 |
Alactasia [description not available] | 0 | 9.82 | 9 | 9 |
Constipation Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | 0 | 9.99 | 10 | 10 |
Lactose Intolerance The condition resulting from the absence or deficiency of LACTASE in the MUCOSA cells of the GASTROINTESTINAL TRACT, and the inability to break down LACTOSE in milk for ABSORPTION. Bacterial fermentation of the unabsorbed lactose leads to symptoms that range from a mild indigestion (DYSPEPSIA) to severe DIARRHEA. Lactose intolerance may be an inborn error or acquired. | 0 | 9.82 | 9 | 9 |
Orphan Diseases Rare diseases that have not been well studied. | 0 | 2.21 | 1 | 0 |
Pyoderma Gangrenosum An idiopathic, rapidly evolving, and severely debilitating disease occurring most commonly in association with chronic ulcerative colitis. It is characterized by the presence of boggy, purplish ulcers with undermined borders, appearing mostly on the legs. The majority of cases are in people between 40 and 60 years old. Its etiology is unknown. | 0 | 2.21 | 1 | 0 |
Skin Ulcer An ULCER of the skin and underlying tissues. | 0 | 2.21 | 1 | 0 |
Bacterial Disease [description not available] | 0 | 2.21 | 1 | 0 |
Bacterial Infections Infections by bacteria, general or unspecified. | 0 | 2.21 | 1 | 0 |
Intertrochanteric Fractures [description not available] | 0 | 4.37 | 4 | 0 |
Hip Fractures Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES). | 0 | 4.37 | 4 | 0 |
Tardive Dystonia [description not available] | 0 | 2.21 | 1 | 0 |
Tardive Dyskinesia Drug-related movement disorder characterized by uncontrollable movements in certain muscles. It is associated with a long-term exposure to certain neuroleptic medications (e.g., METOCLOPRAMIDE). | 0 | 2.21 | 1 | 0 |
Extravascular Hemolysis [description not available] | 0 | 4.06 | 3 | 1 |
Hemolysis The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity. | 0 | 4.06 | 3 | 1 |
Alcohol Abuse [description not available] | 0 | 4.48 | 9 | 0 |
Anemia, Sideroblastic Anemia characterized by the presence of erythroblasts containing excessive deposits of iron in the marrow. | 0 | 5.21 | 20 | 0 |
Alcoholism A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4) | 0 | 4.48 | 9 | 0 |
Diabetic Retinopathy Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION. | 0 | 2.25 | 1 | 0 |
Budd-Chiari Syndrome A condition in which the hepatic venous outflow is obstructed anywhere from the small HEPATIC VEINS to the junction of the INFERIOR VENA CAVA and the RIGHT ATRIUM. Usually the blockage is extrahepatic and caused by blood clots (THROMBUS) or fibrous webs. Parenchymal FIBROSIS is uncommon. | 0 | 2.21 | 1 | 0 |
Pulmonary Sarcoidosis [description not available] | 0 | 2.21 | 1 | 0 |
Pulmonary Consumption [description not available] | 0 | 5.58 | 18 | 0 |
Tuberculosis, Pulmonary MYCOBACTERIUM infections of the lung. | 0 | 5.58 | 18 | 0 |
Sarcoidosis, Pulmonary Sarcoidosis affecting predominantly the lungs, the site most frequently involved and most commonly causing morbidity and mortality in sarcoidosis. Pulmonary sarcoidosis is characterized by sharply circumscribed granulomas in the alveolar, bronchial, and vascular walls, composed of tightly packed cells derived from the mononuclear phagocyte system. The clinical symptoms when present are dyspnea upon exertion, nonproductive cough, and wheezing. (Cecil Textbook of Medicine, 19th ed, p431) | 0 | 2.21 | 1 | 0 |
Chronic Insomnia [description not available] | 0 | 4.18 | 3 | 1 |
Sleep Initiation and Maintenance Disorders Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition. | 0 | 4.18 | 3 | 1 |
Infections, Pneumococcal [description not available] | 0 | 2.08 | 1 | 0 |
Pneumococcal Infections Infections with bacteria of the species STREPTOCOCCUS PNEUMONIAE. | 0 | 2.08 | 1 | 0 |
Cerebral Hemorrhage, Hypertensive [description not available] | 0 | 4.41 | 1 | 1 |
Cerebral Ischemia [description not available] | 0 | 7.49 | 8 | 4 |
Brain Ischemia Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION. | 0 | 7.49 | 8 | 4 |
Acute Disease Disease having a short and relatively severe course. | 0 | 6.19 | 9 | 4 |
Hyperventilation A pulmonary ventilation rate faster than is metabolically necessary for the exchange of gases. It is the result of an increased frequency of breathing, an increased tidal volume, or a combination of both. It causes an excess intake of oxygen and the blowing off of carbon dioxide. | 0 | 2.08 | 1 | 0 |
Panic Attacks [description not available] | 0 | 2.08 | 1 | 0 |
Panic Disorder A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait. | 0 | 2.08 | 1 | 0 |
Harelip [description not available] | 0 | 2.9 | 4 | 0 |
Cleft Palate, Isolated [description not available] | 0 | 3.36 | 7 | 0 |
Cleft Lip Congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences. It is thought to be caused by faulty migration of the mesoderm in the head region. | 0 | 2.9 | 4 | 0 |
Cleft Palate Congenital fissure of the soft and/or hard palate, due to faulty fusion. | 0 | 3.36 | 7 | 0 |
Coagulation Disorders, Blood [description not available] | 0 | 2.08 | 1 | 0 |
Injuries Used with anatomic headings, animals, and sports for wounds and injuries. Excludes cell damage, for which pathology is used. | 0 | 2.08 | 1 | 0 |
Blood Coagulation Disorders Hemorrhagic and thrombotic disorders that occur as a consequence of abnormalities in blood coagulation due to a variety of factors such as COAGULATION PROTEIN DISORDERS; BLOOD PLATELET DISORDERS; BLOOD PROTEIN DISORDERS or nutritional conditions. | 0 | 2.08 | 1 | 0 |
Wounds and Injuries Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity. | 0 | 2.08 | 1 | 0 |
Chromosome Inversion An aberration in which a chromosomal segment is deleted and reinserted in the same place but turned 180 degrees from its original orientation, so that the gene sequence for the segment is reversed with respect to that of the rest of the chromosome. | 0 | 2.08 | 1 | 0 |
Chromosome Deletion Actual loss of portion of a chromosome. | 0 | 2.08 | 1 | 0 |
Affective Disorders [description not available] | 0 | 5.5 | 3 | 1 |
Mood Disorders Those disorders that have a disturbance in mood as their predominant feature. | 0 | 5.5 | 3 | 1 |
Peripheral Arterial Diseases [description not available] | 0 | 2.1 | 1 | 0 |
Peripheral Arterial Disease Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less. | 0 | 2.1 | 1 | 0 |
Chemotherapy-Induced Acral Erythema [description not available] | 0 | 3 | 1 | 0 |
Hand-Foot Syndrome Chemotherapy-induced dermal side effects that are associated with the use of various CYTOSTATIC AGENTS. Symptoms range from mild ERYTHEMA and/or PARESTHESIA to severe ulcerative dermatitis with debilitating pain involving typically palmoplantar and intertriginous areas. These cutaneous manifestations are sometimes accompanied by nail anomalies. | 0 | 3 | 1 | 0 |
Marchiafava-Micheli Syndrome [description not available] | 0 | 2.08 | 1 | 0 |
Hemoglobinuria, Paroxysmal A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins. | 0 | 2.08 | 1 | 0 |
Celiac Sprue [description not available] | 0 | 2.92 | 4 | 0 |
Celiac Disease A malabsorption syndrome that is precipitated by the ingestion of foods containing GLUTEN, such as wheat, rye, and barley. It is characterized by INFLAMMATION of the SMALL INTESTINE, loss of MICROVILLI structure, failed INTESTINAL ABSORPTION, and MALNUTRITION. | 0 | 2.92 | 4 | 0 |
Cancer of Cervix [description not available] | 0 | 2.44 | 2 | 0 |
Uterine Cervical Neoplasms Tumors or cancer of the UTERINE CERVIX. | 0 | 2.44 | 2 | 0 |
Dehydration The condition that results from excessive loss of water from a living organism. | 0 | 3.47 | 1 | 1 |
Gastroenteritis INFLAMMATION of any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Causes of gastroenteritis are many including genetic, infection, HYPERSENSITIVITY, drug effects, and CANCER. | 0 | 3.47 | 1 | 1 |
Electron Transport Chain Deficiencies, Mitochondrial [description not available] | 0 | 2.1 | 1 | 0 |
Amino Acid Metabolism Disorders, Inborn [description not available] | 0 | 4.92 | 5 | 0 |
Mitochondrial Diseases Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes. | 0 | 2.1 | 1 | 0 |
Protein Folding Diseases [description not available] | 0 | 3.01 | 1 | 0 |
Inborn Errors of Metabolism [description not available] | 0 | 4.08 | 5 | 0 |
Metabolism, Inborn Errors Errors in metabolic processes resulting from inborn genetic mutations that are inherited or acquired in utero. | 0 | 4.08 | 5 | 0 |
Coronary Restenosis Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction. | 0 | 6.96 | 9 | 2 |
Gastroduodenal Ulcer [description not available] | 0 | 2.37 | 2 | 0 |
Peptic Ulcer Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS). | 0 | 2.37 | 2 | 0 |
Allergic Reaction [description not available] | 0 | 2.63 | 3 | 0 |
Diseases of Immune System [description not available] | 0 | 2.33 | 2 | 0 |
Hypersensitivity Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen. | 0 | 2.63 | 3 | 0 |
Immune System Diseases Disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-mediated, or both. | 0 | 2.33 | 2 | 0 |
Leukocyte Disorders Disordered formation of various types of leukocytes or an abnormal accumulation or deficiency of these cells. | 0 | 2.33 | 2 | 0 |
Leukocytopenia [description not available] | 0 | 3.76 | 4 | 0 |
Leukopenia A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000). | 0 | 3.76 | 4 | 0 |
Deficiency, Protein [description not available] | 0 | 2.67 | 3 | 0 |
Embolism, Pulmonary [description not available] | 0 | 5.04 | 3 | 1 |
Pulmonary Embolism Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS. | 0 | 5.04 | 3 | 1 |
Cerebral Microangiopathies [description not available] | 0 | 2.1 | 1 | 0 |
Cerebral Small Vessel Diseases Pathological processes or diseases where cerebral MICROVESSELS show abnormalities. They are often associated with aging, hypertension and risk factors for lacunar infarcts (see LACUNAR INFARCTION); LEUKOARAIOSIS; and CEREBRAL HEMORRHAGE. | 0 | 2.1 | 1 | 0 |
Exfoliation Glaucoma [description not available] | 0 | 3.67 | 3 | 0 |
Intraocular Pressure The pressure of the fluids in the eye. | 0 | 3.92 | 4 | 0 |
Exfoliation Syndrome The deposition of flaky, translucent fibrillar material most conspicuous on the anterior lens capsule and pupillary margin but also in both surfaces of the iris, the zonules, trabecular meshwork, ciliary body, corneal endothelium, and orbital blood vessels. It sometimes forms a membrane on the anterior iris surface. Exfoliation refers to the shedding of pigment by the iris. (Newell, Ophthalmology, 7th ed, p380) | 0 | 3.67 | 3 | 0 |
Clasp-Knife Spasticity [description not available] | 0 | 2.1 | 1 | 0 |
Muscle Spasticity A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54) | 0 | 2.1 | 1 | 0 |
Bacterial Pneumonia [description not available] | 0 | 2.1 | 1 | 0 |
Hypoascorbemia [description not available] | 0 | 2.1 | 1 | 0 |
Scurvy An acquired blood vessel disorder caused by severe deficiency of vitamin C (ASCORBIC ACID) in the diet leading to defective collagen formation in small blood vessels. Scurvy is characterized by bleeding in any tissue, weakness, ANEMIA, spongy gums, and a brawny induration of the muscles of the calves and legs. | 0 | 2.1 | 1 | 0 |
Pneumonia, Bacterial Inflammation of the lung parenchyma that is caused by bacterial infections. | 0 | 2.1 | 1 | 0 |
Blood Clot [description not available] | 0 | 5.47 | 8 | 0 |
Thrombosis Formation and development of a thrombus or blood clot in the blood vessel. | 0 | 5.47 | 8 | 0 |
Koch's Disease [description not available] | 0 | 5.77 | 22 | 1 |
Tuberculosis Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM TUBERCULOSIS. | 0 | 10.77 | 22 | 1 |
Poisoning, Lead [description not available] | 0 | 3.65 | 3 | 0 |
Lead Poisoning Poisoning that results from chronic or acute ingestion, injection, inhalation, or skin absorption of LEAD or lead compounds. | 0 | 3.65 | 3 | 0 |
Depression, Involutional Form of depression in those MIDDLE AGE with feelings of ANXIETY. | 0 | 4.95 | 4 | 2 |
Depressive Disorder, Major Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5) | 0 | 4.95 | 4 | 2 |
Pott Disease [description not available] | 0 | 2.1 | 1 | 0 |
Adrenal Gland Diseases Pathological processes of the ADRENAL GLANDS. | 0 | 2.38 | 2 | 0 |
Hematologic Malignancies [description not available] | 0 | 2.1 | 1 | 0 |
Hematologic Neoplasms Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES. | 0 | 2.1 | 1 | 0 |
Deficiency Diseases A condition produced by dietary or metabolic deficiency. The term includes all diseases caused by an insufficient supply of essential nutrients, i.e., protein (or amino acids), vitamins, and minerals. It also includes an inadequacy of calories. (From Dorland, 27th ed; Stedman, 25th ed) | 0 | 3.75 | 2 | 1 |
Bilateral Headache [description not available] | 0 | 3.76 | 2 | 1 |
Anorexia The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA. | 0 | 3.75 | 2 | 1 |
Headache The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS. | 0 | 3.76 | 2 | 1 |
Acute Lymphoid Leukemia [description not available] | 0 | 2.79 | 3 | 0 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias. | 0 | 2.79 | 3 | 0 |
Osteoporotic Fractures Breaks in bones resulting from low bone mass and microarchitectural deterioration characteristic of OSTEOPOROSIS. | 0 | 3.42 | 2 | 0 |
Diabetic Angiopathies VASCULAR DISEASES that are associated with DIABETES MELLITUS. | 0 | 5.82 | 4 | 2 |
Nephrolithiasis Formation of stones in the KIDNEY. | 0 | 2.68 | 3 | 0 |
Atherogenesis [description not available] | 0 | 9.96 | 20 | 4 |
Atherosclerosis A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. | 0 | 9.96 | 20 | 4 |
Diabetic Glomerulosclerosis [description not available] | 0 | 7.98 | 11 | 3 |
Albuminuria The presence of albumin in the urine, an indicator of KIDNEY DISEASES. | 0 | 6.74 | 4 | 2 |
Diabetic Nephropathies KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE. | 0 | 7.98 | 11 | 3 |
Asymptomatic Conditions [description not available] | 0 | 2.11 | 1 | 0 |
Bone Fractures [description not available] | 0 | 5.52 | 7 | 0 |
Fractures, Bone Breaks in bones. | 0 | 5.52 | 7 | 0 |
Acute Onset Aura Migraine [description not available] | 0 | 5.66 | 3 | 2 |
Migraine with Aura A subtype of migraine disorder, characterized by recurrent attacks of reversible neurological symptoms (aura) that precede or accompany the headache. Aura may include a combination of sensory disturbances, such as blurred VISION; HALLUCINATIONS; VERTIGO; NUMBNESS; and difficulty in concentrating and speaking. Aura is usually followed by features of the COMMON MIGRAINE, such as PHOTOPHOBIA; PHONOPHOBIA; and NAUSEA. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1) | 0 | 5.66 | 3 | 2 |
Pleural Effusion, Malignant Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. Malignant pleural effusions often contain actual malignant cells. | 0 | 2.11 | 1 | 0 |
Hypermelanosis [description not available] | 0 | 2.11 | 1 | 0 |
Actinic Reticuloid Syndrome [description not available] | 0 | 2.11 | 1 | 0 |
Hyperpigmentation Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance. | 0 | 2.11 | 1 | 0 |
Psychological Trauma An emotionally painful, shocking, stressful, and sometimes life-threatening experience. It can result from witnessing distressing events such as natural disasters, physical or sexual abuse, and terrorism or other acts of violence. (https://www.nimh.nih.gov/health/) | 0 | 2.11 | 1 | 0 |
Acute Post-Traumatic Stress Disorder [description not available] | 0 | 2.11 | 1 | 0 |
Stress Disorders, Post-Traumatic A class of traumatic stress disorders with symptoms that last more than one month. | 0 | 2.11 | 1 | 0 |
Body Weight, Fetal [description not available] | 0 | 2.13 | 1 | 0 |
Low Tension Glaucoma A form of glaucoma in which chronic optic nerve damage and loss of vision normally attributable to buildup of intraocular pressure occurs despite prevailing conditions of normal intraocular pressure. | 0 | 3.4 | 2 | 0 |
Choroid Neovascularization [description not available] | 0 | 2.11 | 1 | 0 |
Muscular Weakness [description not available] | 0 | 2.11 | 1 | 0 |
Abnormal Deep Tendon Reflex [description not available] | 0 | 2.68 | 3 | 0 |
Reflex, Abnormal An abnormal response to a stimulus applied to the sensory components of the nervous system. This may take the form of increased, decreased, or absent reflexes. | 0 | 2.68 | 3 | 0 |
Muscle Weakness A vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. The weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (From Wyngaarden et al., Cecil Textbook of Medicine, 19th ed, p2251) | 0 | 2.11 | 1 | 0 |
Carcinoma, Anaplastic [description not available] | 0 | 2.88 | 4 | 0 |
Carcinoma A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer. | 0 | 2.88 | 4 | 0 |
Co-infection [description not available] | 0 | 3.03 | 1 | 0 |
ADDH [description not available] | 0 | 3.29 | 6 | 0 |
Attention Deficit Disorder with Hyperactivity A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V) | 0 | 3.29 | 6 | 0 |
Abdominal Aortic Aneurysm [description not available] | 0 | 3.39 | 2 | 0 |
Aortic Aneurysm, Abdominal An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm. | 0 | 3.39 | 2 | 0 |
Amaurosis [description not available] | 0 | 2.37 | 2 | 0 |
Blindness The inability to see or the loss or absence of perception of visual stimuli. This condition may be the result of EYE DISEASES; OPTIC NERVE DISEASES; OPTIC CHIASM diseases; or BRAIN DISEASES affecting the VISUAL PATHWAYS or OCCIPITAL LOBE. | 0 | 2.37 | 2 | 0 |
Cataract, Membranous [description not available] | 0 | 4.14 | 3 | 1 |
Cataract Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed) | 0 | 4.14 | 3 | 1 |
Refractory Depression [description not available] | 0 | 3.03 | 1 | 0 |
Anasarca [description not available] | 0 | 3.59 | 3 | 0 |
Edema Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE. | 0 | 3.59 | 3 | 0 |
Depressive Disorder, Treatment-Resistant Failure to respond to two or more trials of antidepressant monotherapy or failure to respond to four or more trials of different antidepressant therapies. (Campbell's Psychiatric Dictionary, 9th ed.) | 0 | 3.03 | 1 | 0 |
Deficiency, Thiamine [description not available] | 0 | 4.58 | 3 | 0 |
Thiamine Deficiency A nutritional condition produced by a deficiency of THIAMINE in the diet, characterized by anorexia, irritability, and weight loss. Later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. In addition to being caused by a poor diet, thiamine deficiency in the United States most commonly occurs as a result of alcoholism, since ethanol interferes with thiamine absorption. In countries relying on polished rice as a dietary staple, BERIBERI prevalence is very high. (From Cecil Textbook of Medicine, 19th ed, p1171) | 0 | 4.58 | 3 | 0 |
As If Personality [description not available] | 0 | 2.11 | 1 | 0 |
Premenstrual Tension A term used to describe the psychological aspects of PREMENSTRUAL SYNDROME, such as the indescribable tension, depression, hostility, and increased seizure activity in women with seizure disorder. | 0 | 5.83 | 8 | 0 |
Premenstrual Syndrome A combination of distressing physical, psychologic, or behavioral changes that occur during the luteal phase of the menstrual cycle. Symptoms of PMS are diverse (such as pain, water-retention, anxiety, cravings, and depression) and they diminish markedly 2 or 3 days after the initiation of menses. | 0 | 5.83 | 8 | 0 |
Menstruation, Painful [description not available] | 0 | 4.75 | 2 | 0 |
Dysmenorrhea Painful menstruation. | 0 | 4.75 | 2 | 0 |
Skin Diseases, Vascular Skin diseases affecting or involving the cutaneous blood vessels and generally manifested as inflammation, swelling, erythema, or necrosis in the affected area. | 0 | 2.13 | 1 | 0 |
Deep Vein Thrombosis [description not available] | 0 | 7.67 | 7 | 1 |
Venous Thrombosis The formation or presence of a blood clot (THROMBUS) within a vein. | 0 | 7.67 | 7 | 1 |
E coli Infections [description not available] | 0 | 2.13 | 1 | 0 |
Escherichia coli Infections Infections with bacteria of the species ESCHERICHIA COLI. | 0 | 2.13 | 1 | 0 |
Nephrocalcinosis A condition characterized by calcification of the renal tissue itself. It is usually seen in distal RENAL TUBULAR ACIDOSIS with calcium deposition in the DISTAL KIDNEY TUBULES and the surrounding interstitium. Nephrocalcinosis causes RENAL INSUFFICIENCY. | 0 | 3.41 | 2 | 0 |
Low Bone Density [description not available] | 0 | 3.86 | 2 | 1 |
Calcification, Pathologic [description not available] | 0 | 7.66 | 5 | 4 |
Bone Diseases, Metabolic Diseases that affect the METABOLIC PROCESSES of BONE TISSUE. | 0 | 3.86 | 2 | 1 |
Calcinosis Pathologic deposition of calcium salts in tissues. | 0 | 7.66 | 5 | 4 |
Avian Diseases [description not available] | 0 | 2.13 | 1 | 0 |
Heavy Metal Poisoning Poisoning that results from chronic or acute ingestion, injection, inhalation, or skin absorption of HEAVY METALS. Acute and chronic exposures can cause ANEMIA; KIDNEY and LIVER damage; PULMONARY EDEMA; MEMORY LOSS and behavioral changes; bone deformities in children; and MISCARRIAGE or PREMATURE LABOR in pregnant women. | 0 | 2.13 | 1 | 0 |
Poisoning Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure. | 0 | 2.37 | 2 | 0 |
Cochlear Hearing Loss [description not available] | 0 | 4.77 | 2 | 1 |
Deafness, Sudden Complete sensorineural hearing loss which develops suddenly over a period of hours or a few days. | 0 | 3.06 | 1 | 0 |
Hearing Loss, Sensorineural Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM. | 0 | 4.77 | 2 | 1 |
Nodding Syndrome Unexplained neurologic condition characterized by episodes of atonic seizures, convulsions or staring spells with further cognitive decline. | 0 | 2.13 | 1 | 0 |
Endotoxin Shock [description not available] | 0 | 2.13 | 1 | 0 |
Shock, Septic Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status. | 0 | 2.13 | 1 | 0 |
Muscle Disorders [description not available] | 0 | 3.78 | 4 | 0 |
Muscular Diseases Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE. | 0 | 3.78 | 4 | 0 |
Action Tremor [description not available] | 0 | 4.94 | 9 | 1 |
Tremor Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE. | 0 | 4.94 | 9 | 1 |
Colitis Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER. | 0 | 2.5 | 2 | 0 |
Anterior Choroidal Artery Infarction [description not available] | 0 | 2.46 | 2 | 0 |
Cerebral Infarction The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction). | 0 | 2.46 | 2 | 0 |
Deaf Mutism [description not available] | 0 | 2.15 | 1 | 0 |
Deafness A general term for the complete loss of the ability to hear from both ears. | 0 | 2.15 | 1 | 0 |
Athetoid Movements [description not available] | 0 | 2.96 | 1 | 0 |
Infections, Helicobacter [description not available] | 0 | 4.12 | 3 | 1 |
Gastritis, Atrophic GASTRITIS with atrophy of the GASTRIC MUCOSA, the GASTRIC PARIETAL CELLS, and the mucosal glands leading to ACHLORHYDRIA. Atrophic gastritis usually progresses from chronic gastritis. | 0 | 3.43 | 1 | 1 |
Helicobacter Infections Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease. | 0 | 4.12 | 3 | 1 |
Adenoma, Basal Cell [description not available] | 0 | 6.88 | 9 | 3 |
Adenoma A benign epithelial tumor with a glandular organization. | 0 | 6.88 | 9 | 3 |
Aortic Stenosis [description not available] | 0 | 7.65 | 5 | 4 |
Aortic Valve Stenosis A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA. | 0 | 7.65 | 5 | 4 |
Click-Murmur Syndrome [description not available] | 0 | 2.04 | 1 | 0 |
Sprains [description not available] | 0 | 2.36 | 2 | 0 |
Sprains and Strains A collective term for muscle and ligament injuries without dislocation or fracture. A sprain is a joint injury in which some of the fibers of a supporting ligament are ruptured but the continuity of the ligament remains intact. A strain is an overstretching or overexertion of some part of the musculature. | 0 | 2.36 | 2 | 0 |
Anesthesia A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures. | 0 | 3.63 | 10 | 0 |
Chorea Disorders [description not available] | 0 | 1.92 | 1 | 0 |
Chorea Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES. | 0 | 1.92 | 1 | 0 |
Arterial Diseases, Carotid [description not available] | 0 | 7.86 | 5 | 5 |
Carotid Artery Diseases Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology. | 0 | 7.86 | 5 | 5 |
Arterial Inflammation [description not available] | 0 | 4.62 | 3 | 2 |
Hypospadias A birth defect due to malformation of the URETHRA in which the urethral opening is below its normal location. In the male, the malformed urethra generally opens on the ventral surface of the PENIS or on the PERINEUM. In the female, the malformed urethral opening is in the VAGINA. | 0 | 2.05 | 1 | 0 |
Abnormalities, Multiple Congenital abnormalities that affect more than one organ or body structure. | 0 | 2.05 | 1 | 0 |
Abdominal Epilepsy [description not available] | 0 | 2.73 | 3 | 0 |
Lens Dislocation [description not available] | 0 | 2.71 | 3 | 0 |
Phlegmasia Alba Dolens Inflammation that is characterized by swollen, pale, and painful limb. It is usually caused by DEEP VEIN THROMBOSIS in a FEMORAL VEIN, following PARTURITION or an illness. This condition is also called milk leg or white leg. | 0 | 2.05 | 1 | 0 |
Epilepsies, Partial Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317) | 0 | 2.73 | 3 | 0 |
Thrombophlebitis Inflammation of a vein associated with a blood clot (THROMBUS). | 0 | 2.05 | 1 | 0 |
Anterior Ischemic Optic Neuropathy [description not available] | 0 | 2.05 | 1 | 0 |
Hypercoagulability [description not available] | 0 | 5.58 | 6 | 1 |
Dyslipidemia [description not available] | 0 | 2.05 | 1 | 0 |
Optic Neuropathy, Ischemic Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135) | 0 | 2.05 | 1 | 0 |
Thrombophilia A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS. | 0 | 5.58 | 6 | 1 |
Dyslipidemias Abnormalities in the serum levels of LIPIDS, including overproduction or deficiency. Abnormal serum lipid profiles may include high total CHOLESTEROL, high TRIGLYCERIDES, low HIGH DENSITY LIPOPROTEIN CHOLESTEROL, and elevated LOW DENSITY LIPOPROTEIN CHOLESTEROL. | 0 | 2.05 | 1 | 0 |
Cancer of Prostate [description not available] | 0 | 4.34 | 7 | 0 |
Prostatic Neoplasms Tumors or cancer of the PROSTATE. | 0 | 4.34 | 7 | 0 |
Arrhythmia [description not available] | 0 | 2.04 | 1 | 0 |
Arrhythmias, Cardiac Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction. | 0 | 2.04 | 1 | 0 |
Anterior Cerebral Circulation Infarction [description not available] | 0 | 2.43 | 2 | 0 |
Brain Infarction Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis. | 0 | 2.43 | 2 | 0 |
Brain Diseases, Metabolic, Familial [description not available] | 0 | 2.96 | 1 | 0 |
Amyotrophy, Thenar, Of Carpal Origin [description not available] | 0 | 9.58 | 14 | 0 |
Carpal Tunnel Syndrome Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45) | 0 | 9.58 | 14 | 0 |
Colonic Polyps Discrete tissue masses that protrude into the lumen of the COLON. These POLYPS are connected to the wall of the colon either by a stalk, pedunculus, or by a broad base. | 0 | 3.43 | 1 | 1 |
Congenital Limb Deformities [description not available] | 0 | 2.05 | 1 | 0 |
Carotid Artery Narrowing [description not available] | 0 | 5.58 | 3 | 2 |
Carotid Stenosis Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3) | 0 | 5.58 | 3 | 2 |
Cancer of Ovary [description not available] | 0 | 4.35 | 4 | 1 |
Ovarian Neoplasms Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. | 0 | 4.35 | 4 | 1 |
Alcohol Withdrawal Seizures A condition where seizures occur in association with ethanol abuse (ALCOHOLISM) without other identifiable causes. Seizures usually occur within the first 6-48 hours after the cessation of alcohol intake, but may occur during periods of alcohol intoxication. Single generalized tonic-clonic motor seizures are the most common subtype, however, STATUS EPILEPTICUS may occur. (Adams et al., Principles of Neurology, 6th ed, p1174) | 0 | 2.96 | 1 | 0 |
Breathlessness [description not available] | 0 | 2.05 | 1 | 0 |
Icterus [description not available] | 0 | 2.05 | 1 | 0 |
Acute Hypercapnic Respiratory Failure [description not available] | 0 | 2.05 | 1 | 0 |
Mononeuritis [description not available] | 0 | 2.05 | 1 | 0 |
Dyspnea Difficult or labored breathing. | 0 | 2.05 | 1 | 0 |
Jaundice A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction. | 0 | 2.05 | 1 | 0 |
Respiratory Insufficiency Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) | 0 | 2.05 | 1 | 0 |
Mononeuropathies Disease or trauma involving a single peripheral nerve in isolation, or out of proportion to evidence of diffuse peripheral nerve dysfunction. Mononeuropathy multiplex refers to a condition characterized by multiple isolated nerve injuries. Mononeuropathies may result from a wide variety of causes, including ISCHEMIA; traumatic injury; compression; CONNECTIVE TISSUE DISEASES; CUMULATIVE TRAUMA DISORDERS; and other conditions. | 0 | 2.05 | 1 | 0 |
Nerve Degeneration Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways. | 0 | 2.05 | 1 | 0 |
Impotence, Arteriogenic [description not available] | 0 | 2.05 | 1 | 0 |
Anaphylactic Reaction [description not available] | 0 | 2.05 | 1 | 0 |
Anaphylaxis An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death. | 0 | 2.05 | 1 | 0 |
Invasiveness, Neoplasm [description not available] | 0 | 3.87 | 4 | 0 |
Beriberi, Cerebral [description not available] | 0 | 2.05 | 1 | 0 |
Heart Disease, Ischemic [description not available] | 0 | 7.3 | 5 | 1 |
Myocardial Ischemia A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION). | 0 | 7.3 | 5 | 1 |
Barrett Epithelium [description not available] | 0 | 2.05 | 1 | 0 |
Esophageal Reflux [description not available] | 0 | 2.05 | 1 | 0 |
Barrett Esophagus A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus. | 0 | 2.05 | 1 | 0 |
Gastroesophageal Reflux Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER. | 0 | 2.05 | 1 | 0 |
Vascular Diseases Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body. | 0 | 10.72 | 19 | 7 |
Complication, Intraoperative [description not available] | 0 | 3.43 | 1 | 1 |
Elevated Cholesterol [description not available] | 0 | 5.01 | 5 | 2 |
Hypercholesterolemia A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population. | 0 | 5.01 | 5 | 2 |
Smoking Cessation Discontinuing the habit of SMOKING. | 0 | 3.44 | 1 | 1 |
Coxarthrosis [description not available] | 0 | 2.05 | 1 | 0 |
Osteoarthritis, Hip Noninflammatory degenerative disease of the hip joint which usually appears in late middle or old age. It is characterized by growth or maturational disturbances in the femoral neck and head, as well as acetabular dysplasia. A dominant symptom is pain on weight-bearing or motion. | 0 | 2.05 | 1 | 0 |
Abnormalities, Congenital [description not available] | 0 | 2.97 | 1 | 0 |
Dermatitis Seborrheica [description not available] | 0 | 3.04 | 5 | 0 |
Dermatitis, Seborrheic A chronic inflammatory disease of the skin with unknown etiology. It is characterized by moderate ERYTHEMA, dry, moist, or greasy (SEBACEOUS GLAND) scaling and yellow crusted patches on various areas, especially the scalp, that exfoliate as dandruff. Seborrheic dermatitis is common in children and adolescents with HIV INFECTIONS. | 0 | 3.04 | 5 | 0 |
Bone Cancer [description not available] | 0 | 2.05 | 1 | 0 |
Bone Neoplasms Tumors or cancer located in bone tissue or specific BONES. | 0 | 2.05 | 1 | 0 |
Chronic Primary Open Angle Glaucoma [description not available] | 0 | 3.89 | 4 | 0 |
Glaucoma, Open-Angle Glaucoma in which the angle of the anterior chamber is open and the trabecular meshwork does not encroach on the base of the iris. | 0 | 3.89 | 4 | 0 |
Acute Brain Injuries [description not available] | 0 | 3.85 | 2 | 1 |
Brain Injuries Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits. | 0 | 3.85 | 2 | 1 |
Chronic Hepatitis C [description not available] | 0 | 9.67 | 9 | 9 |
Hepatitis C, Chronic INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS. | 0 | 9.67 | 9 | 9 |
Encephalopathy, Traumatic [description not available] | 0 | 3.44 | 1 | 1 |
Brain Injuries, Traumatic A form of acquired brain injury which occurs when a sudden trauma causes damage to the brain. | 0 | 3.44 | 1 | 1 |
Asthenia Clinical sign or symptom manifested as debility, or lack or loss of strength and energy. | 0 | 4.82 | 4 | 2 |
Ataxia Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions. | 0 | 2.05 | 1 | 0 |
Chronic Inflammatory Demyelinating Polyradiculoneuropathy [description not available] | 0 | 2.05 | 1 | 0 |
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating A slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. Clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. The course may be relapsing-remitting or demonstrate a step-wise progression. Protein is usually elevated in the spinal fluid and cranial nerves are typically spared. GUILLAIN-BARRE SYNDROME features a relatively rapid progression of disease which distinguishes it from this condition. (Adams et al., Principles of Neurology, 6th ed, p1337) | 0 | 2.05 | 1 | 0 |
Akinetic-Rigid Variant of Huntington Disease [description not available] | 0 | 2.05 | 1 | 0 |
Huntington Disease A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4) | 0 | 2.05 | 1 | 0 |
Deficiency, Muscle Phosphorylase [description not available] | 0 | 3.83 | 2 | 0 |
Glycogen Storage Disease Type V Glycogenosis due to muscle phosphorylase deficiency. Characterized by painful cramps following sustained exercise. | 0 | 3.83 | 2 | 0 |
Bright Disease A historical classification which is no longer used. It described acute glomerulonephritis, acute nephritic syndrome, or acute nephritis. Named for Richard Bright. | 0 | 2.45 | 2 | 0 |
Acute Porphyria [description not available] | 0 | 2.05 | 1 | 0 |
Glomerulonephritis Inflammation of the renal glomeruli (KIDNEY GLOMERULUS) that can be classified by the type of glomerular injuries including antibody deposition, complement activation, cellular proliferation, and glomerulosclerosis. These structural and functional abnormalities usually lead to HEMATURIA; PROTEINURIA; HYPERTENSION; and RENAL INSUFFICIENCY. | 0 | 2.45 | 2 | 0 |
Nephrotic Syndrome A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction. | 0 | 2.45 | 2 | 0 |
Porphyria, Acute Intermittent An autosomal dominant porphyria that is due to a deficiency of HYDROXYMETHYLBILANE SYNTHASE in the LIVER, the third enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features are recurrent and life-threatening neurologic disturbances, ABDOMINAL PAIN, and elevated level of AMINOLEVULINIC ACID and PORPHOBILINOGEN in the urine. | 0 | 2.05 | 1 | 0 |
Chromosomal Translocation [description not available] | 0 | 2.06 | 1 | 0 |
Coronary Heart Disease [description not available] | 0 | 10.72 | 25 | 3 |
Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. | 0 | 10.72 | 25 | 3 |
Placental Abruption [description not available] | 0 | 2.05 | 1 | 0 |
Abruptio Placentae Premature separation of the normally implanted PLACENTA from the UTERUS. Signs of varying degree of severity include UTERINE BLEEDING, uterine MUSCLE HYPERTONIA, and FETAL DISTRESS or FETAL DEATH. | 0 | 2.05 | 1 | 0 |
Eclampsia Onset of HYPERREFLEXIA; SEIZURES; or COMA in a previously diagnosed pre-eclamptic patient (PRE-ECLAMPSIA). | 0 | 2.05 | 1 | 0 |
Catheter-Associated Infections [description not available] | 0 | 2.06 | 1 | 0 |
Arthritides, Bacterial [description not available] | 0 | 2.06 | 1 | 0 |
Hyperthyroid [description not available] | 0 | 2.06 | 1 | 0 |
Discitis Inflammation of an INTERVERTEBRAL DISC or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others. | 0 | 2.45 | 2 | 0 |
Hyperthyroidism Hypersecretion of THYROID HORMONES from the THYROID GLAND. Elevated levels of thyroid hormones increase BASAL METABOLIC RATE. | 0 | 2.06 | 1 | 0 |
Cancer of Rectum [description not available] | 0 | 2.73 | 3 | 0 |
Rectal Neoplasms Tumors or cancer of the RECTUM. | 0 | 2.73 | 3 | 0 |
Dyskinesia Syndromes [description not available] | 0 | 4.97 | 3 | 1 |
Acathisia, Drug-Induced [description not available] | 0 | 4.74 | 2 | 1 |
Movement Disorders Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions. | 0 | 4.97 | 3 | 1 |
Lupus Erythematosus, Cutaneous, Subacute [description not available] | 0 | 2.98 | 1 | 0 |
Lupus Erythematosus, Cutaneous A form of lupus erythematosus in which the skin may be the only organ involved or in which skin involvement precedes the spread into other body systems. It has been classified into three forms - acute (= LUPUS ERYTHEMATOSUS, SYSTEMIC with skin lesions), subacute, and chronic (= LUPUS ERYTHEMATOSUS, DISCOID). | 0 | 2.98 | 1 | 0 |
Canine Diseases [description not available] | 0 | 2.07 | 1 | 0 |
Urinary Calculi Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID. | 0 | 6.09 | 6 | 2 |
Cell Transformation, Neoplastic Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill. | 0 | 2.07 | 1 | 0 |
MS (Multiple Sclerosis) [description not available] | 0 | 2.06 | 1 | 0 |
Multiple Sclerosis An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903) | 0 | 2.06 | 1 | 0 |
Complications of Diabetes Mellitus [description not available] | 0 | 2.72 | 3 | 0 |
Autoimmune Diabetes [description not available] | 0 | 4.11 | 3 | 1 |
Diabetes Mellitus, Type 1 A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. | 0 | 4.11 | 3 | 1 |
Antibody Deficiency Syndrome [description not available] | 0 | 2.36 | 2 | 0 |
Immunologic Deficiency Syndromes Syndromes in which there is a deficiency or defect in the mechanisms of immunity, either cellular or humoral. | 0 | 2.36 | 2 | 0 |
Aberrant Crypt Foci Clusters of colonic crypts that appear different from the surrounding mucosa when visualized after staining. They are of interest as putative precursors to colorectal adenomas and potential biomarkers for colorectal carcinoma. | 0 | 2.07 | 1 | 0 |
Anterior Circulation Transient Ischemic Attack [description not available] | 0 | 7.68 | 7 | 4 |
Ischemic Attack, Transient Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6) | 0 | 7.68 | 7 | 4 |
Alopecia Cicatrisata [description not available] | 0 | 2.67 | 3 | 0 |
Alopecia Absence of hair from areas where it is normally present. | 0 | 2.67 | 3 | 0 |
Genetic Diseases, X-Chromosome Linked [description not available] | 0 | 4.08 | 16 | 0 |
Erythrohepatic Protoporphyria [description not available] | 0 | 2.07 | 1 | 0 |
Protoporphyria, Erythropoietic An autosomal dominant porphyria that is due to a deficiency of FERROCHELATASE (heme synthetase) in both the LIVER and the BONE MARROW, the last enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features include mainly neurological symptoms, rarely cutaneous lesions, and elevated levels of protoporphyrin and COPROPORPHYRINS in the feces. | 0 | 2.07 | 1 | 0 |
Deficiency, Ascorbic Acid [description not available] | 0 | 2.99 | 1 | 0 |
Ascorbic Acid Deficiency A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177) | 0 | 2.99 | 1 | 0 |
Primary Hyperparathyroidism [description not available] | 0 | 2.07 | 1 | 0 |
Hyperparathyroidism, Primary A condition of abnormally elevated output of PARATHYROID HORMONE due to parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. It is characterized by the combination of HYPERCALCEMIA, phosphaturia, elevated renal 1,25-DIHYDROXYVITAMIN D3 synthesis, and increased BONE RESORPTION. | 0 | 2.07 | 1 | 0 |
Pigmentary Retinopathy [description not available] | 0 | 2.05 | 1 | 0 |
Retinitis Pigmentosa Hereditary, progressive degeneration of the retina due to death of ROD PHOTORECEPTORS initially and subsequent death of CONE PHOTORECEPTORS. It is characterized by deposition of pigment in the retina. | 0 | 2.05 | 1 | 0 |
Hypertriglyceridemia A condition of elevated levels of TRIGLYCERIDES in the blood. | 0 | 3.46 | 1 | 1 |
Branch Retinal Artery Occlusion [description not available] | 0 | 2.07 | 1 | 0 |
Retinal Artery Occlusion Sudden ISCHEMIA in the RETINA due to blocked blood flow through the CENTRAL RETINAL ARTERY or its branches leading to sudden complete or partial loss of vision, respectively, in the eye. | 0 | 2.07 | 1 | 0 |
Microsatellite Instability The occurrence of highly polymorphic mono- and dinucleotide MICROSATELLITE REPEATS in somatic cells. It is a form of genome instability associated with defects in DNA MISMATCH REPAIR. | 0 | 2.07 | 1 | 0 |
Infarct, Lacunar [description not available] | 0 | 4.37 | 1 | 1 |
Biological Clock Disturbances [description not available] | 0 | 2.07 | 1 | 0 |
Seasonal Affective Disorders [description not available] | 0 | 3 | 1 | 0 |
Seasonal Affective Disorder A syndrome characterized by depressions that recur annually at the same time each year, usually during the winter months. Other symptoms include anxiety, irritability, decreased energy, increased appetite (carbohydrate cravings), increased duration of sleep, and weight gain. SAD (seasonal affective disorder) can be treated by daily exposure to bright artificial lights (PHOTOTHERAPY), during the season of recurrence. | 0 | 3 | 1 | 0 |
Injury, Ischemia-Reperfusion [description not available] | 0 | 3 | 1 | 0 |
Reperfusion Injury Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA. | 0 | 3 | 1 | 0 |
Brain Hemorrhage, Cerebral [description not available] | 0 | 2.08 | 1 | 0 |
Cerebral Hemorrhage Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA. | 0 | 2.08 | 1 | 0 |
AIDS-Related Opportunistic Infections Opportunistic infections found in patients who test positive for human immunodeficiency virus (HIV). The most common include PNEUMOCYSTIS PNEUMONIA, Kaposi's sarcoma, cryptosporidiosis, herpes simplex, toxoplasmosis, cryptococcosis, and infections with Mycobacterium avium complex, Microsporidium, and Cytomegalovirus. | 0 | 3.39 | 1 | 1 |
Impairment, Light Touch Sensation [description not available] | 0 | 2.01 | 1 | 0 |
Coronary Artery Stenosis [description not available] | 0 | 3.39 | 1 | 1 |
Coronary Stenosis Narrowing or constriction of a coronary artery. | 0 | 3.39 | 1 | 1 |
Arteriosclerosis Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries. | 0 | 14.86 | 30 | 3 |
Post-Natal Depression [description not available] | 0 | 2.42 | 2 | 0 |
Depression, Postpartum Depression in POSTPARTUM WOMEN, usually within four weeks after giving birth (PARTURITION). The degree of depression ranges from mild transient depression to neurotic or psychotic depressive disorders. (From DSM-IV, p386) | 0 | 2.42 | 2 | 0 |
Labor, Premature [description not available] | 0 | 2.41 | 2 | 0 |
Infant, Small for Gestational Age An infant having a birth weight lower than expected for its gestational age. | 0 | 2.01 | 1 | 0 |
Arterial Obstructive Diseases [description not available] | 0 | 5.01 | 3 | 1 |
Diseases, Peripheral Vascular [description not available] | 0 | 7.02 | 6 | 2 |
Arterial Occlusive Diseases Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency. | 0 | 5.01 | 3 | 1 |
Peripheral Vascular Diseases Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART. | 0 | 7.02 | 6 | 2 |
Cancer of the Uterus [description not available] | 0 | 2.01 | 1 | 0 |
Hormone-Dependent Neoplasms [description not available] | 0 | 2.01 | 1 | 0 |
Uterine Neoplasms Tumors or cancer of the UTERUS. | 0 | 2.01 | 1 | 0 |
Adamantiades-Behcet Disease [description not available] | 0 | 3.8 | 2 | 1 |
Behcet Syndrome Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well. | 0 | 3.8 | 2 | 1 |
Developmental Psychomotor Disorders [description not available] | 0 | 2.01 | 1 | 0 |
Sicca Syndrome [description not available] | 0 | 2.01 | 1 | 0 |
Sjogren's Syndrome Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis. | 0 | 2.01 | 1 | 0 |
Alcohol-Induced Peripheral Neuropathy [description not available] | 0 | 2.92 | 1 | 0 |
Liver Dysfunction [description not available] | 0 | 2.87 | 4 | 0 |
Liver Diseases Pathological processes of the LIVER. | 0 | 2.87 | 4 | 0 |
Pink Eye [description not available] | 0 | 2.36 | 2 | 0 |
Mucositis, Oral [description not available] | 0 | 2.36 | 2 | 0 |
Hand Dermatosis [description not available] | 0 | 2.01 | 1 | 0 |
Foot Dermatoses Skin diseases of the foot, general or unspecified. | 0 | 2.01 | 1 | 0 |
Conjunctivitis INFLAMMATION of the CONJUNCTIVA. | 0 | 2.36 | 2 | 0 |
Hand Dermatoses Skin diseases involving the HANDS. | 0 | 2.01 | 1 | 0 |
Stomatitis INFLAMMATION of the soft tissues of the MOUTH, such as MUCOSA; PALATE; GINGIVA; and LIP. | 0 | 2.36 | 2 | 0 |
Pellagra A disease due to deficiency of NIACIN, a B-complex vitamin, or its precursor TRYPTOPHAN. It is characterized by scaly DERMATITIS which is often associated with DIARRHEA and DEMENTIA (the three D's). | 0 | 2.33 | 2 | 0 |
Disease A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown. | 0 | 3.31 | 7 | 0 |
Palsy [description not available] | 0 | 2.33 | 2 | 0 |
Brachial Paresis [description not available] | 0 | 1.93 | 1 | 0 |
Paralysis A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45) | 0 | 2.33 | 2 | 0 |
Sarcoma, Epithelioid [description not available] | 0 | 2.33 | 2 | 0 |
EHS Tumor [description not available] | 0 | 1.93 | 1 | 0 |
Sarcoma A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant. | 0 | 2.33 | 2 | 0 |
Corns [description not available] | 0 | 1.93 | 1 | 0 |
Callosities Localized hyperplasia of the horny layer of the epidermis due to pressure or friction. (Dorland, 27th ed) | 0 | 1.93 | 1 | 0 |
Complement Deficiencies [description not available] | 0 | 1.93 | 1 | 0 |
Dermatitis Exfoliativa [description not available] | 0 | 1.93 | 1 | 0 |
Dermatitis, Exfoliative The widespread involvement of the skin by a scaly, erythematous dermatitis occurring either as a secondary or reactive process to an underlying cutaneous disorder (e.g., atopic dermatitis, psoriasis, etc.), or as a primary or idiopathic disease. It is often associated with the loss of hair and nails, hyperkeratosis of the palms and soles, and pruritus. (From Dorland, 27th ed) | 0 | 1.93 | 1 | 0 |
Infant Malnutrition Malnutrition, occurring in infants ages 1 month to 24 months, which is due to insufficient intake of food, dietary nutrients, or a pathophysiologic condition which prevents the absorption and utilization of food. Growth and development are markedly affected. | 0 | 2.34 | 2 | 0 |
Autosomal Dominant Juvenile Parkinson Disease [description not available] | 0 | 3.25 | 2 | 0 |
Parkinsonian Disorders A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA. | 0 | 3.25 | 2 | 0 |
Leukemia, Lymphocytic [description not available] | 0 | 1.93 | 1 | 0 |
Leukemia, Lymphoid Leukemia associated with HYPERPLASIA of the lymphoid tissues and increased numbers of circulating malignant LYMPHOCYTES and lymphoblasts. | 0 | 1.93 | 1 | 0 |
Corynebacterium diphtheriae Infection [description not available] | 0 | 1.93 | 1 | 0 |
Diphtheria A localized infection of mucous membranes or skin caused by toxigenic strains of CORYNEBACTERIUM DIPHTHERIAE. It is characterized by the presence of a pseudomembrane at the site of infection. DIPHTHERIA TOXIN, produced by C. diphtheriae, can cause myocarditis, polyneuritis, and other systemic toxic effects. | 0 | 1.93 | 1 | 0 |
Narcosis A state of depressed CENTRAL NERVOUS SYSTEM marked by stupor or insensibility. | 0 | 2.33 | 2 | 0 |
Neuritis A general term indicating inflammation of a peripheral or cranial nerve. Clinical manifestation may include PAIN; PARESTHESIAS; PARESIS; or HYPESTHESIA. | 0 | 4.93 | 9 | 0 |
Fibrosarcoma A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed) | 0 | 2.33 | 2 | 0 |
Hospital-Acquired Condition [description not available] | 0 | 2.33 | 2 | 0 |
Agitation, Psychomotor [description not available] | 0 | 2.36 | 2 | 0 |
Insulin Coma Severe HYPOGLYCEMIA induced by a large dose of exogenous INSULIN resulting in a COMA or profound state of unconsciousness from which the individual cannot be aroused. | 0 | 1.93 | 1 | 0 |
Psychomotor Agitation A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions. | 0 | 2.36 | 2 | 0 |
Alcoholic Intoxication An acute brain syndrome which results from the excessive ingestion of ETHANOL or ALCOHOLIC BEVERAGES. | 0 | 3.43 | 8 | 0 |
Infectious Diseases [description not available] | 0 | 2.62 | 3 | 0 |
Communicable Diseases An illness caused by an infectious agent or its toxins that occurs through the direct or indirect transmission of the infectious agent or its products from an infected individual or via an animal, vector or the inanimate environment to a susceptible animal or human host. | 0 | 2.62 | 3 | 0 |
Air Sickness [description not available] | 0 | 3.03 | 5 | 0 |
Motion Sickness Disorder caused by motion. It includes sea sickness, train sickness, roller coaster rides, rocking chair, hammock swing, car sickness, air sickness, or SPACE MOTION SICKNESS. Symptoms include nausea, vomiting and/or dizziness. | 0 | 3.03 | 5 | 0 |
Anti-MuSK Myasthenia Gravis [description not available] | 0 | 1.93 | 1 | 0 |
Myasthenia Gravis A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition. | 0 | 1.93 | 1 | 0 |
Emesis, Postoperative [description not available] | 0 | 2.33 | 2 | 0 |
Postoperative Nausea and Vomiting Emesis and queasiness occurring after anesthesia. | 0 | 2.33 | 2 | 0 |
Polyarthritis [description not available] | 0 | 2.34 | 2 | 0 |
Arthritis Acute or chronic inflammation of JOINTS. | 0 | 2.34 | 2 | 0 |
Appetite Disorders [description not available] | 0 | 1.93 | 1 | 0 |
Feeding and Eating Disorders A group of disorders characterized by physiological and psychological disturbances in appetite or food intake. | 0 | 1.93 | 1 | 0 |
Audiogenic Epilepsy [description not available] | 0 | 2.84 | 4 | 0 |
Epilepsy, Reflex A subtype of epilepsy characterized by seizures that are consistently provoked by a certain specific stimulus. Auditory, visual, and somatosensory stimuli as well as the acts of writing, reading, eating, and decision making are examples of events or activities that may induce seizure activity in affected individuals. (From Neurol Clin 1994 Feb;12(1):57-8) | 0 | 2.84 | 4 | 0 |
Starvation Lengthy and continuous deprivation of food. (Stedman, 25th ed) | 0 | 2.84 | 4 | 0 |
Infection, Toxoplasma gondii [description not available] | 0 | 1.93 | 1 | 0 |
Toxoplasmosis The acquired form of infection by Toxoplasma gondii in animals and man. | 0 | 1.93 | 1 | 0 |
Biotinidase Deficiency The late onset form of MULTIPLE CARBOXYLASE DEFICIENCY (deficiency of the activities of biotin-dependent enzymes propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, and PYRUVATE CARBOXYLASE) due to a defect or deficiency in biotinidase which is essential for recycling BIOTIN. | 0 | 1.93 | 1 | 0 |
Nephritis Inflammation of any part of the KIDNEY. | 0 | 1.93 | 1 | 0 |
Water-Electrolyte Imbalance Disturbances in the body's WATER-ELECTROLYTE BALANCE. | 0 | 1.93 | 1 | 0 |
Acid-Base Imbalance Disturbances in the ACID-BASE EQUILIBRIUM of the body. | 0 | 1.93 | 1 | 0 |
Electrolytes Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed) | 0 | 2.34 | 2 | 0 |
Cramp [description not available] | 0 | 1.93 | 1 | 0 |
Muscle Cramp A sustained and usually painful contraction of muscle fibers. This may occur as an isolated phenomenon or as a manifestation of an underlying disease process (e.g., UREMIA; HYPOTHYROIDISM; MOTOR NEURON DISEASE; etc.). (From Adams et al., Principles of Neurology, 6th ed, p1398) | 0 | 1.93 | 1 | 0 |
Experimental Mammary Neoplasms [description not available] | 0 | 1.93 | 1 | 0 |
Blepharitis Inflammation of the eyelids. | 0 | 1.93 | 1 | 0 |
Cranial Nerve II Diseases [description not available] | 0 | 2.34 | 2 | 0 |
Psychoses, Alcoholic A group of mental disorders associated with organic brain damage and caused by poisoning from alcohol. | 0 | 1.93 | 1 | 0 |
Optic Nerve Diseases Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect. | 0 | 2.34 | 2 | 0 |
Anterior Optic Neuritis [description not available] | 0 | 1.93 | 1 | 0 |
Optic Neuritis Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis). | 0 | 1.93 | 1 | 0 |
Hepatitis, Infectious [description not available] | 0 | 3.03 | 5 | 0 |
Hepatitis INFLAMMATION of the LIVER. | 0 | 3.03 | 5 | 0 |
Hepatitis A INFLAMMATION of the LIVER in humans caused by a member of the HEPATOVIRUS genus, HUMAN HEPATITIS A VIRUS. It can be transmitted through fecal contamination of food or water. | 0 | 3.03 | 5 | 0 |
Hematuria Presence of blood in the urine. | 0 | 1.93 | 1 | 0 |
Cardiomyopathies, Primary [description not available] | 0 | 2.34 | 2 | 0 |
Cardiomyopathies A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS). | 0 | 2.34 | 2 | 0 |
Blood Diseases [description not available] | 0 | 2.86 | 4 | 0 |
Hematologic Diseases Disorders of the blood and blood forming tissues. | 0 | 2.86 | 4 | 0 |
Bilirubin Encephalopathy [description not available] | 0 | 1.93 | 1 | 0 |
Kernicterus A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613) | 0 | 1.93 | 1 | 0 |
Duhring Disease [description not available] | 0 | 1.93 | 1 | 0 |
Gestational Pemphigoid [description not available] | 0 | 1.93 | 1 | 0 |
Dermatitis Herpetiformis Rare, chronic, papulo-vesicular disease characterized by an intensely pruritic eruption consisting of various combinations of symmetrical, erythematous, papular, vesicular, or bullous lesions. The disease is strongly associated with the presence of HLA-B8 and HLA-DR3 antigens. A variety of different autoantibodies has been detected in small numbers in patients with dermatitis herpetiformis. | 0 | 1.93 | 1 | 0 |
Diffuse Mixed Small and Large Cell Lymphoma [description not available] | 0 | 2.37 | 2 | 0 |
Lymphoma, Non-Hodgkin Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease. | 0 | 2.37 | 2 | 0 |
Anemia, Hypochromic Anemia characterized by a decrease in the ratio of the weight of hemoglobin to the volume of the erythrocyte, i.e., the mean corpuscular hemoglobin concentration is less than normal. The individual cells contain less hemoglobin than they could have under optimal conditions. Hypochromic anemia may be caused by iron deficiency from a low iron intake, diminished iron absorption, or excessive iron loss. It can also be caused by infections or other diseases, therapeutic drugs, lead poisoning, and other conditions. (Stedman, 25th ed; from Miale, Laboratory Medicine: Hematology, 6th ed, p393) | 0 | 4.8 | 13 | 0 |
Infant, Newborn, Diseases Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts. | 0 | 2.63 | 3 | 0 |
Experimental Radiation Injuries [description not available] | 0 | 2.85 | 4 | 0 |
Carcinoma, Ehrlich Tumor A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms. | 0 | 1.93 | 1 | 0 |
Choline Deficiency A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984) | 0 | 1.93 | 1 | 0 |
Lathyrism A paralytic condition of the legs caused by ingestion of lathyrogens, especially BETA-AMINOPROPIONITRILE or beta-N-oxalyl amino-L-alanine, which are found in the seeds of plants of the genus LATHYRUS. | 0 | 1.93 | 1 | 0 |
Abdominal Cramps [description not available] | 0 | 2.34 | 2 | 0 |
Burns Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like. | 0 | 1.93 | 1 | 0 |
Kwashiorkor A syndrome produced by severe protein deficiency, characterized by retarded growth, changes in skin and hair pigment, edema, and pathologic changes in the liver, including fatty infiltration, necrosis, and fibrosis. The word is a local name in Gold Coast, Africa, meaning displaced child. Although first reported from Africa, kwashiorkor is now known throughout the world, but mainly in the tropics and subtropics. It is considered to be related to marasmus. (From Dorland, 27th ed) | 0 | 2.34 | 2 | 0 |
Gastric Diseases [description not available] | 0 | 1.93 | 1 | 0 |
Bronze Diabetes [description not available] | 0 | 2.85 | 4 | 0 |
Hemochromatosis A disorder of iron metabolism characterized by a triad of HEMOSIDEROSIS; LIVER CIRRHOSIS; and DIABETES MELLITUS. It is caused by massive iron deposits in parenchymal cells that may develop after a prolonged increase of iron absorption. (Jablonski's Dictionary of Syndromes & Eponymic Diseases, 2d ed) | 0 | 2.85 | 4 | 0 |
Actinic Keratosis [description not available] | 0 | 1.93 | 1 | 0 |
Keratoderma Blennorrhagicum [description not available] | 0 | 1.93 | 1 | 0 |
Keratosis Any horny growth such as a wart or callus. | 0 | 1.93 | 1 | 0 |
Keratosis, Actinic White or pink lesions on the arms, hands, face, or scalp that arise from sun-induced DNA DAMAGE to KERATINOCYTES in exposed areas. They are considered precursor lesions to superficial SQUAMOUS CELL CARCINOMA. | 0 | 1.93 | 1 | 0 |
Dermatitis, Occupational A recurrent contact dermatitis caused by substances found in the work place. | 0 | 2.34 | 2 | 0 |
Basal Ganglia Diseases Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA. | 0 | 4.02 | 3 | 1 |
Hemosiderosis Conditions in which there is a generalized increase in the iron stores of body tissues, particularly of liver and the MONONUCLEAR PHAGOCYTE SYSTEM, without demonstrable tissue damage. The name refers to the presence of stainable iron in the tissue in the form of hemosiderin. | 0 | 1.93 | 1 | 0 |
Heavy Menstrual Bleeding [description not available] | 0 | 2.34 | 2 | 0 |
Bleeding Between Periods [description not available] | 0 | 2.34 | 2 | 0 |
Hemorrhage, Uterine [description not available] | 0 | 2.34 | 2 | 0 |
Menorrhagia Excessive uterine bleeding during MENSTRUATION. | 0 | 2.34 | 2 | 0 |
Metrorrhagia Abnormal uterine bleeding that is not related to MENSTRUATION, usually in females without regular MENSTRUAL CYCLE. The irregular and unpredictable bleeding usually comes from a dysfunctional ENDOMETRIUM. | 0 | 2.34 | 2 | 0 |
Uterine Hemorrhage Bleeding from blood vessels in the UTERUS, sometimes manifested as vaginal bleeding. | 0 | 2.34 | 2 | 0 |
Caries, Dental [description not available] | 0 | 3.54 | 3 | 0 |
Dental Caries Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp. | 0 | 3.54 | 3 | 0 |
Bile Duct Cancer [description not available] | 0 | 1.93 | 1 | 0 |
Bile Duct Neoplasms Tumors or cancer of the BILE DUCTS. | 0 | 1.93 | 1 | 0 |
Calculosis [description not available] | 0 | 1.93 | 1 | 0 |
Anemia, Cooley's [description not available] | 0 | 2.34 | 2 | 0 |
beta-Thalassemia A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent. | 0 | 2.34 | 2 | 0 |
Anemia, Megaloblastic A disorder characterized by the presence of ANEMIA, abnormally large red blood cells (megalocytes or macrocytes), and MEGALOBLASTS. | 0 | 1.93 | 1 | 0 |
Sebaceous Gland Diseases Diseases of the sebaceous glands such as sebaceous hyperplasia and sebaceous cell carcinoma (SEBACEOUS GLAND NEOPLASMS). | 0 | 1.93 | 1 | 0 |
Dermatitis Any inflammation of the skin. | 0 | 2.33 | 2 | 0 |
Anemia, Macrocytic Anemia characterized by larger than normal erythrocytes, increased mean corpuscular volume (MCV) and increased mean corpuscular hemoglobin (MCH). | 0 | 1.93 | 1 | 0 |
Curling Ulcer Acute stress DUODENAL ULCER, usually observed in patients with extensive third-degree burns. | 0 | 1.93 | 1 | 0 |
Duodenal Ulcer A PEPTIC ULCER located in the DUODENUM. | 0 | 1.93 | 1 | 0 |
Achlorhydria A lack of HYDROCHLORIC ACID in GASTRIC JUICE despite stimulation of gastric secretion. | 0 | 1.93 | 1 | 0 |
Nerve Pain [description not available] | 0 | 1.93 | 1 | 0 |
Spinal Diseases Diseases involving the SPINE. | 0 | 1.93 | 1 | 0 |
Bone Diseases Diseases of BONES. | 0 | 1.93 | 1 | 0 |
Neuralgia Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve. | 0 | 1.93 | 1 | 0 |
Dermatitis, Eczematous [description not available] | 0 | 1.93 | 1 | 0 |
Lichen Simplex Chronicus [description not available] | 0 | 1.93 | 1 | 0 |
Eczema A pruritic papulovesicular dermatitis occurring as a reaction to many endogenous and exogenous agents (Dorland, 27th ed). | 0 | 1.93 | 1 | 0 |
Neurodermatitis An extremely variable eczematous skin disease that is presumed to be a response to prolonged vigorous scratching, rubbing, or pinching to relieve intense pruritus. It varies in intensity, severity, course, and morphologic expression in different individuals. Neurodermatitis is believed by some to be psychogenic. The circumscribed or localized form is often referred to as lichen simplex chronicus. | 0 | 1.93 | 1 | 0 |
Intermittent Claudication A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE. | 0 | 4.67 | 2 | 1 |
Agranulocytosis A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS). | 0 | 3.54 | 3 | 0 |
Thalassemias [description not available] | 0 | 2.85 | 1 | 0 |
Thalassemia A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia. | 0 | 2.85 | 1 | 0 |
Cephalgia, Vascular [description not available] | 0 | 1.93 | 1 | 0 |
Thrombocytopathy [description not available] | 0 | 1.94 | 1 | 0 |
Hemorrhagic Fever, Epidemic [description not available] | 0 | 1.94 | 1 | 0 |
Blood Platelet Disorders Disorders caused by abnormalities in platelet count or function. | 0 | 1.94 | 1 | 0 |
Hemorrhagic Fever with Renal Syndrome An acute febrile disease occurring predominately in Asia. It is characterized by fever, prostration, vomiting, hemorrhagic phenonema, shock, and renal failure. It is caused by any one of several closely related species of the genus Hantavirus. The most severe form is caused by HANTAAN VIRUS whose natural host is the rodent Apodemus agrarius. Milder forms are caused by SEOUL VIRUS and transmitted by the rodents Rattus rattus and R. norvegicus, and the PUUMALA VIRUS with transmission by Clethrionomys galreolus. | 0 | 1.94 | 1 | 0 |
Biliary Calculi [description not available] | 0 | 1.94 | 1 | 0 |
Gallstone Disease [description not available] | 0 | 1.94 | 1 | 0 |
Cholelithiasis Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS). | 0 | 1.94 | 1 | 0 |
Gallstones Solid crystalline precipitates in the BILIARY TRACT, usually formed in the GALLBLADDER, resulting in the condition of CHOLELITHIASIS. Gallstones, derived from the BILE, consist mainly of calcium, cholesterol, or bilirubin. | 0 | 1.94 | 1 | 0 |
Sarcoma 180 An experimental sarcoma of mice. | 0 | 2.63 | 3 | 0 |
Leukemia L 1210 [description not available] | 0 | 1.94 | 1 | 0 |
Focal Neurologic Deficits [description not available] | 0 | 2.34 | 2 | 0 |
Experimental Leukemia [description not available] | 0 | 1.94 | 1 | 0 |
Empyema, Gall Bladder [description not available] | 0 | 1.94 | 1 | 0 |
Cholecystitis Inflammation of the GALLBLADDER; generally caused by impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, or other diseases. | 0 | 1.94 | 1 | 0 |
Bodily Distress Disorder [description not available] | 0 | 1.94 | 1 | 0 |
Cirrhoses, Experimental Liver [description not available] | 0 | 1.94 | 1 | 0 |
Aortic Diseases Pathological processes involving any part of the AORTA. | 0 | 1.94 | 1 | 0 |
Encephalomyelitis, Inflammatory [description not available] | 0 | 1.94 | 1 | 0 |
Encephalomyelitis A general term indicating inflammation of the BRAIN and SPINAL CORD, often used to indicate an infectious process, but also applicable to a variety of autoimmune and toxic-metabolic conditions. There is significant overlap regarding the usage of this term and ENCEPHALITIS in the literature. | 0 | 1.94 | 1 | 0 |
Anemia, Hemolytic, Acquired [description not available] | 0 | 1.93 | 1 | 0 |
Anemia, Hemolytic A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES). | 0 | 1.93 | 1 | 0 |
Carcinosarcoma A malignant neoplasm that contains elements of carcinoma and sarcoma so extensively intermixed as to indicate neoplasia of epithelial and mesenchymal tissue. (Stedman, 25th ed) | 0 | 1.93 | 1 | 0 |
Cardiac Toxicity [description not available] | 0 | 1.93 | 1 | 0 |
Cardiotoxicity Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION. | 0 | 1.93 | 1 | 0 |
Malignant Carcinoid Syndrome A symptom complex associated with CARCINOID TUMOR and characterized by attacks of severe flushing of the skin, diarrheal watery stools, bronchoconstriction, sudden drops in blood pressure, edema, and ascites. The carcinoid tumors are usually located in the gastrointestinal tract and metastasize to the liver. Symptoms are caused by tumor secretion of serotonin, prostaglandins, and other biologically active substances. Cardiac manifestations constitute CARCINOID HEART DISEASE. (Dorland, 27th ed; Stedman, 25th ed) | 0 | 1.93 | 1 | 0 |
Pleurisy INFLAMMATION of PLEURA, the lining of the LUNG. When PARIETAL PLEURA is involved, there is pleuritic CHEST PAIN. | 0 | 1.93 | 1 | 0 |
Cervical Tuberculous Lymphadenitis [description not available] | 0 | 1.93 | 1 | 0 |
Dysentery Acute inflammation of the intestine associated with infectious DIARRHEA of various etiologies, generally acquired by eating contaminated food containing TOXINS, BIOLOGICAL derived from BACTERIA or other microorganisms. Dysentery is characterized initially by watery FECES then by bloody mucoid stools. It is often associated with ABDOMINAL PAIN; FEVER; and DEHYDRATION. | 0 | 1.93 | 1 | 0 |
Dysentery, Shiga bacillus [description not available] | 0 | 1.93 | 1 | 0 |
Dysentery, Bacillary DYSENTERY caused by gram-negative rod-shaped enteric bacteria (ENTEROBACTERIACEAE), most often by the genus SHIGELLA. Shigella dysentery, Shigellosis, is classified into subgroups according to syndrome severity and the infectious species. Group A: SHIGELLA DYSENTERIAE (severest); Group B: SHIGELLA FLEXNERI; Group C: SHIGELLA BOYDII; and Group D: SHIGELLA SONNEI (mildest). | 0 | 1.93 | 1 | 0 |
Biliary or Urinary Stones [description not available] | 0 | 1.93 | 1 | 0 |
Cold Fingers, Hereditary [description not available] | 0 | 1.93 | 1 | 0 |
Raynaud Disease An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress. | 0 | 1.93 | 1 | 0 |
Cerebral Arteriosclerosis [description not available] | 0 | 5.8 | 4 | 2 |
Intracranial Arteriosclerosis Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS. | 0 | 5.8 | 4 | 2 |
Ischemia A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION. | 0 | 3.4 | 1 | 1 |
Acute Autoimmune Neuropathy [description not available] | 0 | 2 | 1 | 0 |
Guillain-Barre Syndrome An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314) | 0 | 2 | 1 | 0 |
Dysesthesia [description not available] | 0 | 2.01 | 1 | 0 |
Urinary Tract Infections Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA. | 0 | 3.81 | 2 | 1 |
Complications, Hematologic Pregnancy [description not available] | 0 | 2.02 | 1 | 0 |
Agnogenic Myeloid Metaplasia [description not available] | 0 | 2.33 | 2 | 0 |
Splenic Diseases Diseases involving the SPLEEN. | 0 | 2.33 | 2 | 0 |
Myeloproliferative Disorders Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE. | 0 | 2.33 | 2 | 0 |
Primary Myelofibrosis A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone. | 0 | 2.33 | 2 | 0 |
Metaplasia A condition in which there is a change of one adult cell type to another similar adult cell type. | 0 | 1.92 | 1 | 0 |
Hansen Disease [description not available] | 0 | 1.92 | 1 | 0 |
Leprosy A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid. | 0 | 1.92 | 1 | 0 |
Neutropenia A decrease in the number of NEUTROPHILS found in the blood. | 0 | 2.36 | 2 | 0 |
Pancreatic Diseases Pathological processes of the PANCREAS. | 0 | 1.93 | 1 | 0 |
Coxsackie Virus Infections [description not available] | 0 | 1.93 | 1 | 0 |
Retinal Degeneration A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304) | 0 | 1.92 | 1 | 0 |
HbS Disease [description not available] | 0 | 2.42 | 2 | 0 |
Anemia, Sickle Cell A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S. | 0 | 2.42 | 2 | 0 |
Thromboembolism Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream. | 0 | 7.88 | 9 | 2 |
Glycogenosis [description not available] | 0 | 2.93 | 1 | 0 |
Glycogen Storage Disease A group of inherited metabolic disorders involving the enzymes responsible for the synthesis and degradation of glycogen. In some patients, prominent liver involvement is presented. In others, more generalized storage of glycogen occurs, sometimes with prominent cardiac involvement. | 0 | 2.93 | 1 | 0 |
Asymmetric Diabetic Proximal Motor Neuropathy [description not available] | 0 | 3.35 | 2 | 0 |
Diabetic Neuropathies Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325) | 0 | 3.35 | 2 | 0 |
Alcohol Abuse, Nervous System [description not available] | 0 | 2.02 | 1 | 0 |
Activated Protein C Resistance A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance. | 0 | 2.02 | 1 | 0 |
Anti-Phospholipid Antibody Syndrome [description not available] | 0 | 2.42 | 2 | 0 |
Antiphospholipid Syndrome The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR). | 0 | 2.42 | 2 | 0 |
Cleft Spine [description not available] | 0 | 2.02 | 1 | 0 |
47,XX,+21 [description not available] | 0 | 2.42 | 2 | 0 |
Down Syndrome A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213) | 0 | 2.42 | 2 | 0 |
Infections, Mycobacterium [description not available] | 0 | 2.02 | 1 | 0 |
Pancytopenia Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets. | 0 | 2.02 | 1 | 0 |
Mycobacterium Infections Infections with bacteria of the genus MYCOBACTERIUM. | 0 | 2.02 | 1 | 0 |
Chemical Sensitivities, Multiple [description not available] | 0 | 2.02 | 1 | 0 |
Inflammatory Response Syndrome, Systemic [description not available] | 0 | 2.93 | 1 | 0 |
Systemic Inflammatory Response Syndrome A systemic inflammatory response to a variety of clinical insults, characterized by two or more of the following conditions: (1) fever | 0 | 2.93 | 1 | 0 |
Marfan Syndrome, Type I [description not available] | 0 | 3.63 | 3 | 0 |
Marfan Syndrome An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome (type 1) is associated with mutations in the gene encoding FIBRILLIN-1 (FBN1), a major element of extracellular microfibrils of connective tissue. Mutations in the gene encoding TYPE II TGF-BETA RECEPTOR (TGFBR2) are associated with Marfan syndrome type 2. | 0 | 3.63 | 3 | 0 |
Dissecting Vertebral Artery Aneurysm [description not available] | 0 | 2.02 | 1 | 0 |
Hemolysis, Elevated Liver Enzymes, Lowered Platelets [description not available] | 0 | 2.02 | 1 | 0 |
Placental Insufficiency Failure of the PLACENTA to deliver an adequate supply of nutrients and OXYGEN to the FETUS. | 0 | 2.02 | 1 | 0 |
HELLP Syndrome A syndrome of HEMOLYSIS, elevated liver ENZYMES, and low blood platelets count (THROMBOCYTOPENIA). HELLP syndrome is observed in pregnant women with PRE-ECLAMPSIA or ECLAMPSIA who also exhibit LIVER damage and abnormalities in BLOOD COAGULATION. | 0 | 2.02 | 1 | 0 |
Plasmodium falciparum Malaria [description not available] | 0 | 2.02 | 1 | 0 |
Malaria, Falciparum Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations. | 0 | 2.02 | 1 | 0 |
Segond Fracture [description not available] | 0 | 3.4 | 1 | 1 |
Tibial Fractures Fractures of the TIBIA. | 0 | 3.4 | 1 | 1 |
Central Hypothyroidism [description not available] | 0 | 2.02 | 1 | 0 |
Hypothyroidism A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction. | 0 | 2.02 | 1 | 0 |
Leukoaraiosis Non-specific white matter changes in the BRAIN, often seen after age 65. Changes include loss of AXONS; MYELIN pallor, GLIOSIS, loss of ependymal cells, and enlarged perivascular spaces. Leukoaraiosis is a risk factor for DEMENTIA and CEREBROVASCULAR DISORDERS. | 0 | 2.02 | 1 | 0 |
Bewilderment [description not available] | 0 | 2.02 | 1 | 0 |
Dermatosclerosis [description not available] | 0 | 2.02 | 1 | 0 |
Scleroderma, Localized A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules. | 0 | 2.02 | 1 | 0 |
Pachymeningitis [description not available] | 0 | 3.41 | 1 | 1 |
Meningitis Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6) | 0 | 3.41 | 1 | 1 |
Tuberculosis, Drug-Resistant [description not available] | 0 | 2.03 | 1 | 0 |
Bone Tuberculosis [description not available] | 0 | 2.03 | 1 | 0 |
Tuberculosis, Multidrug-Resistant Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS. | 0 | 2.03 | 1 | 0 |
Marasmus [description not available] | 0 | 2.02 | 1 | 0 |
Protein-Energy Malnutrition The lack of sufficient energy or protein to meet the body's metabolic demands, as a result of either an inadequate dietary intake of protein, intake of poor quality dietary protein, increased demands due to disease, or increased nutrient losses. | 0 | 2.02 | 1 | 0 |
Carbohydrate Inducible Hyperlipemia [description not available] | 0 | 2.43 | 2 | 0 |
Hyperlipoproteinemia Type IV A hypertriglyceridemia disorder, often with autosomal dominant inheritance. It is characterized by the persistent elevations of plasma TRIGLYCERIDES, endogenously synthesized and contained predominantly in VERY-LOW-DENSITY LIPOPROTEINS (pre-beta lipoproteins). In contrast, the plasma CHOLESTEROL and PHOSPHOLIPIDS usually remain within normal limits. | 0 | 2.43 | 2 | 0 |
Disc, Herniated [description not available] | 0 | 2.02 | 1 | 0 |
Nearsightedness [description not available] | 0 | 2.71 | 3 | 0 |
Retinal Pigment Epithelial Detachment [description not available] | 0 | 2.02 | 1 | 0 |
Intervertebral Disc Displacement An INTERVERTEBRAL DISC in which the NUCLEUS PULPOSUS has protruded through surrounding ANNULUS FIBROSUS. This occurs most frequently in the lower lumbar region. | 0 | 2.02 | 1 | 0 |
Myopia A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness. | 0 | 2.71 | 3 | 0 |
Retinal Detachment Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12). | 0 | 2.02 | 1 | 0 |
Adjuvant Arthritis [description not available] | 0 | 2.02 | 1 | 0 |
Parasitemia The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed) | 0 | 2.03 | 1 | 0 |
Trypanosomiasis Infection with protozoa of the genus TRYPANOSOMA. | 0 | 2.03 | 1 | 0 |
Benign Symmetrical Lipomatosis [description not available] | 0 | 2.02 | 1 | 0 |
Cardiac Arrest, Sudden [description not available] | 0 | 9.64 | 9 | 9 |
Death, Sudden, Cardiac Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005) | 0 | 9.64 | 9 | 9 |
Developmental Coordination Disorder [description not available] | 0 | 2.03 | 1 | 0 |
Biliary Cirrhosis [description not available] | 0 | 2.03 | 1 | 0 |
Liver Cirrhosis, Biliary FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes. | 0 | 2.03 | 1 | 0 |
Eczema, Atopic [description not available] | 0 | 2.03 | 1 | 0 |
Allergy, Food [description not available] | 0 | 2.03 | 1 | 0 |
Dermatitis, Atopic A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema. | 0 | 2.03 | 1 | 0 |
Food Hypersensitivity Gastrointestinal disturbances, skin eruptions, or shock due to allergic reactions to allergens in food. | 0 | 2.03 | 1 | 0 |
Branch Vein Occlusion [description not available] | 0 | 2.44 | 2 | 0 |
Glaucoma An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed) | 0 | 2.03 | 1 | 0 |
Retinal Vein Occlusion Blockage of the RETINAL VEIN. Those at high risk for this condition include patients with HYPERTENSION; DIABETES MELLITUS; ATHEROSCLEROSIS; and other CARDIOVASCULAR DISEASES. | 0 | 2.44 | 2 | 0 |
Chronic Hepatitis B [description not available] | 0 | 2.03 | 1 | 0 |
Hypesthesia Absent or reduced sensitivity to cutaneous stimulation. | 0 | 2.03 | 1 | 0 |
Hepatitis B, Chronic INFLAMMATION of the LIVER in humans caused by HEPATITIS B VIRUS lasting six months or more. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact. | 0 | 2.03 | 1 | 0 |
Pervasive Child Development Disorders [description not available] | 0 | 2.03 | 1 | 0 |
Child Development Disorders, Pervasive Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements. | 0 | 2.03 | 1 | 0 |
Bone Loss, Perimenopausal [description not available] | 0 | 2.03 | 1 | 0 |
Osteoporosis, Postmenopausal Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency. | 0 | 2.03 | 1 | 0 |
Posterior Vitreous Detachment [description not available] | 0 | 2.03 | 1 | 0 |
Brain Thrombosis [description not available] | 0 | 2.03 | 1 | 0 |
Coronary Thrombosis Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION. | 0 | 2.03 | 1 | 0 |
Common Variable Hypogammaglobulinemia [description not available] | 0 | 3.43 | 1 | 1 |
Common Variable Immunodeficiency Heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections. | 0 | 3.43 | 1 | 1 |
Dilatation, Pathologic The condition of an anatomical structure's being dilated beyond normal dimensions. | 0 | 2.03 | 1 | 0 |
Abortion, Tubal [description not available] | 0 | 2.42 | 2 | 0 |
Abortion, Spontaneous Expulsion of the product of FERTILIZATION before completing the term of GESTATION and without deliberate interference. | 0 | 2.42 | 2 | 0 |
Bone Loss, Osteoclastic [description not available] | 0 | 2.03 | 1 | 0 |
Cerebral Infarction, Middle Cerebral Artery [description not available] | 0 | 2.03 | 1 | 0 |
Infarction, Middle Cerebral Artery NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction. | 0 | 2.03 | 1 | 0 |
Sensation Disorders Disorders of the special senses (i.e., VISION; HEARING; TASTE; and SMELL) or somatosensory system (i.e., afferent components of the PERIPHERAL NERVOUS SYSTEM). | 0 | 2.03 | 1 | 0 |
Kawasaki Disease [description not available] | 0 | 3.42 | 1 | 1 |
Mucocutaneous Lymph Node Syndrome An acute, febrile, mucocutaneous condition accompanied by swelling of cervical lymph nodes in infants and young children. The principal symptoms are fever, congestion of the ocular conjunctivae, reddening of the lips and oral cavity, protuberance of tongue papillae, and edema or erythema of the extremities. | 0 | 3.42 | 1 | 1 |
Dyskinesia, Medication-Induced [description not available] | 0 | 3.42 | 1 | 1 |
Dyskinesia, Drug-Induced Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199) | 0 | 3.42 | 1 | 1 |
Lead Poisoning, Nervous System Injury to the nervous system secondary to exposure to lead compounds. Two distinct clinical patterns occur in children (LEAD POISONING, NERVOUS SYSTEM, CHILDHOOD) and adults (LEAD POISONING, NERVOUS SYSTEM, ADULT). In children, lead poisoning typically produces an encephalopathy. In adults, exposure to toxic levels of lead is associated with a peripheral neuropathy. | 0 | 2.04 | 1 | 0 |
HPV Infection [description not available] | 0 | 2 | 1 | 0 |
Fibroma, Shope [description not available] | 0 | 2 | 1 | 0 |
Papillomavirus Infections Neoplasms of the skin and mucous membranes caused by papillomaviruses. They are usually benign but some have a high risk for malignant progression. | 0 | 2 | 1 | 0 |
Apolipoprotein B-100, Familial Defective [description not available] | 0 | 3.39 | 1 | 1 |
Hyperlipoproteinemia Type II A group of familial disorders characterized by elevated circulating cholesterol contained in either LOW-DENSITY LIPOPROTEINS alone or also in VERY-LOW-DENSITY LIPOPROTEINS (pre-beta lipoproteins). | 0 | 3.39 | 1 | 1 |
Facial Palsy [description not available] | 0 | 3.39 | 1 | 1 |
Auricular Syndrome of Ramsay Hunt [description not available] | 0 | 3.39 | 1 | 1 |
Brain Vascular Disorders [description not available] | 0 | 2 | 1 | 0 |
Cerebrovascular Disorders A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others. | 0 | 2 | 1 | 0 |
Astigmatism Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less diffuse area. This results from the radius of curvature in one plane being longer or shorter than the radius at right angles to it. (Dorland, 27th ed) | 0 | 2 | 1 | 0 |
Kidney Failure A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. | 0 | 3.39 | 1 | 1 |
Renal Insufficiency Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE. | 0 | 3.39 | 1 | 1 |
Dermatitis Medicamentosa [description not available] | 0 | 2 | 1 | 0 |
Facial Dermatoses Skin diseases involving the FACE. | 0 | 2 | 1 | 0 |
Acne Rosacea [description not available] | 0 | 2 | 1 | 0 |
Rosacea A cutaneous disorder primarily of convexities of the central part of the FACE, such as FOREHEAD; CHEEK; NOSE; and CHIN. It is characterized by FLUSHING; ERYTHEMA; EDEMA; RHINOPHYMA; papules; and ocular symptoms. It may occur at any age but typically after age 30. There are various subtypes of rosacea: erythematotelangiectatic, papulopustular, phymatous, and ocular (National Rosacea Society's Expert Committee on the Classification and Staging of Rosacea, J Am Acad Dermatol 2002; 46:584-7). | 0 | 2 | 1 | 0 |
Fusiform Aneurysm Elongated, spindle-shaped dilation in the wall of blood vessels, usually large ARTERIES with ATHEROSCLEROSIS. | 0 | 2.01 | 1 | 0 |
Aneurysm Pathological outpouching or sac-like dilatation in the wall of any blood vessel (ARTERIES or VEINS) or the heart (HEART ANEURYSM). It indicates a thin and weakened area in the wall which may later rupture. Aneurysms are classified by location, etiology, or other characteristics. | 0 | 2.01 | 1 | 0 |
SC Disease [description not available] | 0 | 2.01 | 1 | 0 |
Hemoglobin SC Disease One of the sickle cell disorders characterized by the presence of both hemoglobin S and hemoglobin C. It is similar to, but less severe than sickle cell anemia. | 0 | 2.01 | 1 | 0 |
Autoimmune Disease [description not available] | 0 | 2.91 | 1 | 0 |
Connective Tissue Disease, Mixed [description not available] | 0 | 2.91 | 1 | 0 |
Autoimmune Diseases Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides. | 0 | 2.91 | 1 | 0 |
Abortion, Threatened UTERINE BLEEDING from a GESTATION of less than 20 weeks without any CERVICAL DILATATION. It is characterized by vaginal bleeding, lower back discomfort, or midline pelvic cramping and a risk factor for MISCARRIAGE. | 0 | 2 | 1 | 0 |
Retinal Diseases Diseases involving the RETINA. | 0 | 2.92 | 1 | 0 |
Rheumatism [description not available] | 0 | 1.94 | 1 | 0 |
Rheumatic Diseases Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement. | 0 | 1.94 | 1 | 0 |