Page last updated: 2024-10-31

methyl salicylate and Sensitivity and Specificity

methyl salicylate has been researched along with Sensitivity and Specificity in 36 studies

methyl salicylate: used in over-the-counter liniments, ointments, lotions for relief of musculoskeletal aches and pains; has hemolytic effect on human & sheep erythrocytes; RN given refers to parent cpd; structure in Merck Index, 9th ed, #5990
methyl salicylate : A benzoate ester that is the methyl ester of salicylic acid.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"In pollen-related food allergy, extracts for skin prick tests (SPTs) are often not standardized, and the test reliability is affected by false-negative reactions."2.70Component-resolved diagnosis with recombinant allergens in patients with cherry allergy. ( Ballmer-Weber, BK; Cistero-Bahima, A; Enrique, E; Fritsche, P; Haase, T; Scheurer, S; Wüthrich, B, 2002)
"High-dose, subcutaneous IT is efficacious and safe in patients with severe birch pollen rhinoconjunctivitis and asthma."2.70The safety and efficacy of subcutaneous birch pollen immunotherapy - a one-year, randomised, double-blind, placebo-controlled study. ( Bødtger, U; Jacobi, HH; Malling, HJ; Poulsen, LK, 2002)
"All patients were tested with four allergy test methods (SPT, ImmunoCAP, Microtest and ISAC 112) and a total of 3485 pairwise test results were analysed and compared."1.43Evaluation of a novel automated allergy microarray platform compared with three other allergy test methods. ( Baldracchini, F; El-Shanawany, T; Hui, V; Jolles, S; Önell, A; Williams, P, 2016)
"Procyanidins were studied by using hydrophilic interaction liquid chromatography combined with high-resolution ESI-TOF-MS."1.37Birch inner bark procyanidins can be resolved with enhanced sensitivity by hydrophilic interaction HPLC-MS. ( Karonen, M; Liimatainen, J; Sinkkonen, J, 2011)
"The Swiss Society for Immunology and Allergy and the Swiss external quality centers had launched a program for total IgE, IgE specific for cat epithelium, birch pollen and peanut, and multi-specific IgE."1.36[External quality controls for allergy analysis in the Quality Control Center Switzerland from 2006 to 2008]. ( Albe, X; Dayer, E; Kesseler, D; Morandi, PA; Roux-Lombard, P, 2010)
"In birch-pollen-associated food allergy to celery, carrot and apple, Bet v 1, Api g 1, Dau c 1 and Mal d 1 are major allergens."1.33In vitro analysis of birch-pollen-associated food allergy by use of recombinant allergens in the basophil activation test. ( Erdmann, SM; Hoffmann-Sommergruber, K; Kwiecien, R; Maderegger, B; Merk, HF; Moll-Slodowy, S; Sachs, B; Sauer, I; Scheiner, O; Schmidt, A, 2005)
"Pollen-related food allergy to fresh fruits and vegetables is a well-known clinical phenomenon."1.32Diagnostic value of birch recombinant allergens (rBet v 1, profilin rBet v 2) in children with pollen-related food allergy. ( Cudowska, B; Kaczmarski, M, 2004)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.78)18.2507
2000's19 (52.78)29.6817
2010's15 (41.67)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Smith, JN1
Noll, RJ1
Cooks, RG2
Pauwels, J1
D'Autry, W1
Van den Bossche, L1
Dewever, C1
Forier, M1
Vandenwaeyenberg, S1
Wolfs, K1
Hoogmartens, J1
Van Schepdael, A1
Adams, E1
Riter, LS1
Laughlin, BC1
Nikolaev, E1
Nazarov, EG1
Coy, SL1
Krylov, EV1
Miller, RA1
Eiceman, GA1
Kakkar, T1
Mayersohn, M1
Baek, HS1
Jeong, JW1
Lee, HB1
Kwon, JW1
Tyszczuk-Rotko, K1
Wójciak-Kosior, M1
Sowa, I1
Czarnobilska, E1
Gregorius, A1
Porebski, G1
Spiewak, R1
Sacha, M1
Villalta, D2
Da Re, M1
Conte, M1
Martelli, P1
Uasuf, CG1
Barrale, M1
La Chiusa, SM1
Brusca, I1
Thomsen, GF1
Schlünssen, V1
Skadhauge, LR1
Malling, TH1
Sherson, DL1
Omland, Ø1
Sigsgaard, T1
Williams, P1
Önell, A1
Baldracchini, F1
Hui, V1
Jolles, S1
El-Shanawany, T1
Kronsteiner, B1
Dullnig, V1
Stutz, H1
Aerts, NE1
Dombrecht, EJ1
Bridts, CH3
Hagendorens, MM3
de Clerck, LS3
Stevens, WJ3
Ebo, DG3
Focke, M1
Marth, K1
Valenta, R2
Pree, I1
Reisinger, J1
Bohle, B2
Frantal, S1
Niederberger, V1
Verweij, MM1
De Knop, KJ1
Asero, R1
Dayer, E1
Kesseler, D1
Morandi, PA1
Albe, X1
Roux-Lombard, P1
Barnes, CS1
Amado, M1
Bodtger, U1
Assing, K1
Poulsen, LK2
Ballmer-Weber, BK2
Hoffmann-Sommergruber, K2
Skypala, IJ1
Calderon, MA1
Leeds, AR1
Emery, P1
Till, SJ1
Durham, SR1
Karonen, M1
Liimatainen, J1
Sinkkonen, J1
Scheurer, S1
Fritsche, P1
Enrique, E1
Cistero-Bahima, A1
Haase, T1
Wüthrich, B1
Pittertschatscher, K1
Hochreiter, R2
Thalhamer, J2
Hammerl, P1
Jahn-Schmid, B1
Harwanegg, C1
Hiller, R2
Ebner, C1
Scheiner, O2
Mueller, MW1
Brackmann, C1
Aldén, M1
Bengtsson, PE1
Davidsson, KO1
Pettersson, JB1
Hartl, A1
Stepanoska, T1
Ferreira, F1
Cudowska, B1
Kaczmarski, M1
Schuerwegh, AJ1
Erdmann, SM1
Sachs, B1
Schmidt, A1
Merk, HF1
Moll-Slodowy, S1
Sauer, I1
Kwiecien, R1
Maderegger, B1
Gotlib, T1
Samoliński, B1
Grzanka, A1
Wöhrl, S1
Vigl, K1
Zehetmayer, S1
Jarisch, R1
Prinz, M1
Stingl, G1
Kopp, T1
Vahlkvist, S1
Sinding, M1
Skamstrup, K1
Bisgaard, H1
Kaul, S1
Lüttkopf, D1
Kastner, B1
Vogel, L1
Höltz, G1
Vieths, S1
Hoffmann, A1
Bødtger, U1
Jacobi, HH1
Malling, HJ1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Changes in Adaptive Immune Responses and Effector Cell Responses Upon Nasal Allergen Exposure - a Pilot Study[NCT03644680]36 participants (Actual)Interventional2018-09-24Completed
Contribution of Local Nasal IgE Production to the Boost of Systemic Allergen-specific IgE Production Upon Nasal Allergen Contact - an Explorative Pilot Study[NCT05042830]30 participants (Anticipated)Interventional2021-11-11Recruiting
The Diagnosis of Oral Allergy Syndrome Through the Use of a Structured Questionnaire[NCT00854958]123 participants (Actual)Observational2005-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for methyl salicylate and Sensitivity and Specificity

ArticleYear
Molecular diagnosis of fruit and vegetable allergy.
    Current opinion in allergy and clinical immunology, 2011, Volume: 11, Issue:3

    Topics: Allergens; Antigens, Plant; Betula; Diagnosis, Differential; Food Hypersensitivity; Fruit; Humans; I

2011

Trials

4 trials available for methyl salicylate and Sensitivity and Specificity

ArticleYear
Development and validation of a structured questionnaire for the diagnosis of oral allergy syndrome in subjects with seasonal allergic rhinitis during the UK birch pollen season.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2011, Volume: 41, Issue:7

    Topics: Adult; Aged; Algorithms; Betula; Cross Reactions; Double-Blind Method; Female; Food Hypersensitivity

2011
Component-resolved diagnosis with recombinant allergens in patients with cherry allergy.
    The Journal of allergy and clinical immunology, 2002, Volume: 110, Issue:1

    Topics: Adolescent; Adult; Allergens; Antigens, Plant; Betula; Child; Cross Reactions; Double-Blind Method;

2002
The performance of a component-based allergen-microarray in clinical practice.
    Allergy, 2006, Volume: 61, Issue:5

    Topics: Adult; Allergens; Animals; Artemisia; Betula; Cats; Cohort Studies; Female; Humans; Hypersensitivity

2006
The safety and efficacy of subcutaneous birch pollen immunotherapy - a one-year, randomised, double-blind, placebo-controlled study.
    Allergy, 2002, Volume: 57, Issue:4

    Topics: Adult; Allergens; Antibody Specificity; Betula; Conjunctivitis, Allergic; Desensitization, Immunolog

2002

Other Studies

31 other studies available for methyl salicylate and Sensitivity and Specificity

ArticleYear
Facility monitoring of chemical warfare agent simulants in air using an automated, field-deployable, miniature mass spectrometer.
    Rapid communications in mass spectrometry : RCM, 2011, May-30, Volume: 25, Issue:10

    Topics: Air; Chemical Warfare Agents; Malonates; Miniaturization; Models, Chemical; Mustard Gas; Organophosp

2011
Optimization and validation of liquid chromatography and headspace-gas chromatography based methods for the quantitative determination of capsaicinoids, salicylic acid, glycol monosalicylate, methyl salicylate, ethyl salicylate, camphor and l-menthol in a
    Journal of pharmaceutical and biomedical analysis, 2012, Feb-23, Volume: 60

    Topics: Analgesics, Non-Narcotic; Camphor; Capsaicin; Chromatography, Gas; Chromatography, Liquid; Liquid-Li

2012
Direct analysis of volatile organic compounds in human breath using a miniaturized cylindrical ion trap mass spectrometer with a membrane inlet.
    Rapid communications in mass spectrometry : RCM, 2002, Volume: 16, Issue:24

    Topics: Acrolein; Breath Tests; Humans; Ions; Mass Spectrometry; Membranes, Artificial; Organic Chemicals; R

2002
Pressure effects in differential mobility spectrometry.
    Analytical chemistry, 2006, Nov-15, Volume: 78, Issue:22

    Topics: Air Pressure; Algorithms; Ions; Mass Spectrometry; Microchemistry; Organophosphonates; Organophospho

2006
Simultaneous quantitative analysis of methyl salicylate, ethyl salicylate and salicylic acid from biological fluids using gas chromatography-mass spectrometry.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Oct-23, Volume: 718, Issue:1

    Topics: Animals; Body Fluids; Gas Chromatography-Mass Spectrometry; Liver; Male; Rats; Rats, Sprague-Dawley;

1998
Molecular sensitization patterns in birch pollen-sensitized Korean children according to the presence of oral allergy syndrome.
    Medicine, 2020, Volume: 99, Issue:10

    Topics: Adolescent; Allergens; Betula; Child; Child, Preschool; Cross Reactions; Female; Food Hypersensitivi

2020
Voltammetric determination of betulinic acid at lead film electrode after chromatographic separation in plant material.
    Analytical biochemistry, 2013, May-15, Volume: 436, Issue:2

    Topics: Betula; Betulinic Acid; Calibration; Chromatography, High Pressure Liquid; Electrochemistry; Electro

2013
[The benefits of using basophil activation test as a diagnostic tool prior to specific immunotherapy with inhalant allergens].
    Przeglad lekarski, 2012, Volume: 69, Issue:12

    Topics: Administration, Inhalation; Adolescent; Allergens; Animals; Basophils; Betula; Biotransformation; Ch

2012
Allergen component specific ige measurement with the Immulite™ 2000 system: diagnostic accuracy and intermethod comparison.
    Journal of clinical laboratory analysis, 2015, Volume: 29, Issue:2

    Topics: Allergens; Animals; Betula; Cross Reactions; Food Hypersensitivity; Humans; Hypersensitivity; Immuno

2015
Are allergen batch differences and the use of double skin prick test important?
    BMC pulmonary medicine, 2015, Apr-09, Volume: 15

    Topics: Adult; Allergens; Alternaria; Animals; Artemisia; Betula; Cats; Cladosporium; Dander; Dogs; Female;

2015
Evaluation of a novel automated allergy microarray platform compared with three other allergy test methods.
    Clinical and experimental immunology, 2016, Volume: 184, Issue:1

    Topics: Adult; Allergens; Animals; Arachis; Betula; Cats; Diagnostic Tests, Routine; Dogs; Female; Humans; H

2016
Validation of capillary zone electrophoresis and capillary isoelectric focusing separations optimized for the characterization of two recombinant products of the birch pollen allergen Bet v 1a.
    Electrophoresis, 2008, Volume: 29, Issue:12

    Topics: Allergens; Antigens, Plant; Betula; Electrophoresis, Capillary; Isoelectric Focusing; Pollen; Recomb

2008
Simultaneous flow cytometric detection of basophil activation marker CD63 and intracellular phosphorylated p38 mitogen-activated protein kinase in birch pollen allergy.
    Cytometry. Part B, Clinical cytometry, 2009, Volume: 76, Issue:1

    Topics: Antigens, Plant; Basophils; Betula; Case-Control Studies; Enzyme Activation; Flow Cytometry; Humans;

2009
Molecular composition and biological activity of commercial birch pollen allergen extracts.
    European journal of clinical investigation, 2009, Volume: 39, Issue:5

    Topics: Adult; Aged; Allergens; Antigens, Plant; Betula; Female; Humans; Hypersensitivity; Immunoblotting; M

2009
Molecular composition and biological activity of commercial birch pollen allergen extracts.
    European journal of clinical investigation, 2009, Volume: 39, Issue:5

    Topics: Adult; Aged; Allergens; Antigens, Plant; Betula; Female; Humans; Hypersensitivity; Immunoblotting; M

2009
Molecular composition and biological activity of commercial birch pollen allergen extracts.
    European journal of clinical investigation, 2009, Volume: 39, Issue:5

    Topics: Adult; Aged; Allergens; Antigens, Plant; Betula; Female; Humans; Hypersensitivity; Immunoblotting; M

2009
Molecular composition and biological activity of commercial birch pollen allergen extracts.
    European journal of clinical investigation, 2009, Volume: 39, Issue:5

    Topics: Adult; Aged; Allergens; Antigens, Plant; Betula; Female; Humans; Hypersensitivity; Immunoblotting; M

2009
A sensitive assay for the detection of IgE bound to the major birch pollen allergen, Bet v 1, in the form of immune complexes.
    Journal of immunological methods, 2009, Jun-30, Volume: 345, Issue:1-2

    Topics: Allergens; Antibodies, Monoclonal; Antigen-Antibody Complex; Betula; Enzyme-Linked Immunosorbent Ass

2009
Sensitization profiles in birch pollen-allergic patients with and without oral allergy syndrome to apple: lessons from multiplexed component-resolved allergy diagnosis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2010, Volume: 40, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Allergens; Antigen-Antibody Reactions; Antigens, Plan

2010
Is the detection of IgE to multiple Bet v 1-homologous food allergens by means of allergen microarray clinically useful?
    The Journal of allergy and clinical immunology, 2010, Volume: 125, Issue:5

    Topics: Adolescent; Adult; Allergens; Antigen-Antibody Complex; Antigens, Plant; Betula; Food Hypersensitivi

2010
[External quality controls for allergy analysis in the Quality Control Center Switzerland from 2006 to 2008].
    Revue medicale suisse, 2010, Apr-21, Volume: 6, Issue:245

    Topics: Allergens; Animals; Arachis; Betula; Biomarkers; Cats; Clinical Laboratory Techniques; Humans; Hyper

2010
They tell me I'm allergic to ragweed.
    International archives of allergy and immunology, 2011, Volume: 155, Issue:3

    Topics: Allergens; Ambrosia; Betula; Humans; Immunoglobulin E; Poaceae; Rhinitis, Allergic, Seasonal; Sensit

2011
A prospective, clinical study on asymptomatic sensitisation and development of allergic rhinitis: high negative predictive value of allergological testing.
    International archives of allergy and immunology, 2011, Volume: 155, Issue:3

    Topics: Adult; Allergens; Betula; Denmark; Female; Humans; Immunoglobulin E; Incidence; Male; Middle Aged; P

2011
Birch inner bark procyanidins can be resolved with enhanced sensitivity by hydrophilic interaction HPLC-MS.
    Journal of separation science, 2011, Volume: 34, Issue:22

    Topics: Betula; Chromatography, High Pressure Liquid; Plant Bark; Plant Extracts; Proanthocyanidins; Sensiti

2011
Quantification of histamine in blood plasma and cell culture supernatants: a validated one-step gas chromatography-mass spectrometry method.
    Analytical biochemistry, 2002, Sep-15, Volume: 308, Issue:2

    Topics: Allergens; Animals; Anthracenes; Basophil Degranulation Test; Basophils; beta-N-Acetylhexosaminidase

2002
Allergen microarray: comparison of microarray using recombinant allergens with conventional diagnostic methods to detect allergen-specific serum immunoglobulin E.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2003, Volume: 33, Issue:10

    Topics: Allergens; Antibody Specificity; Betula; Enzyme-Linked Immunosorbent Assay; Humans; Hypersensitivity

2003
Optical and mass spectrometric study of the pyrolysis gas of wood particles.
    Applied spectroscopy, 2003, Volume: 57, Issue:2

    Topics: Anisotropy; Betula; Energy Transfer; Gases; Hot Temperature; Lasers; Mass Spectrometry; Optics and P

2003
Characterization of the protective and therapeutic efficiency of a DNA vaccine encoding the major birch pollen allergen Bet v 1a.
    Allergy, 2004, Volume: 59, Issue:1

    Topics: Allergens; Animals; Betula; Desensitization, Immunologic; Disease Models, Animal; Female; Hypersensi

2004
Diagnostic value of birch recombinant allergens (rBet v 1, profilin rBet v 2) in children with pollen-related food allergy.
    Roczniki Akademii Medycznej w Bialymstoku (1995), 2004, Volume: 49

    Topics: Adolescent; Allergens; Antigens, Plant; Asthma; Betula; Child; Child, Preschool; Contractile Protein

2004
Flow cytometric analysis of in vitro activated basophils, specific IgE and skin tests in the diagnosis of pollen-associated food allergy.
    Cytometry. Part B, Clinical cytometry, 2005, Volume: 64, Issue:1

    Topics: Adolescent; Adult; Aged; Antigens, CD; Basophils; Betula; Female; Flow Cytometry; Food Hypersensitiv

2005
In vitro analysis of birch-pollen-associated food allergy by use of recombinant allergens in the basophil activation test.
    International archives of allergy and immunology, 2005, Volume: 136, Issue:3

    Topics: Allergens; Antibodies, Monoclonal; Antigens, CD; Antigens, Plant; Basophils; Betula; Europe; Flow Cy

2005
Bilateral nasal allergen provocation monitored with acoustic rhinometry. Assessment of both nasal passages and the side reacting with greater congestion: relation to the nasal cycle.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2005, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Allergens; Betula; Female; Humans; Male; Nasal Mucosa; Nasal Provocation Tests; P

2005
Daily home measurements of exhaled nitric oxide in asthmatic children during natural birch pollen exposure.
    The Journal of allergy and clinical immunology, 2006, Volume: 117, Issue:6

    Topics: Adolescent; Allergens; Asthma; Betula; Biomarkers; Child; Child, Preschool; Feasibility Studies; Fem

2006
Mediator release assays based on human or murine immunoglobulin E in allergen standardization.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2007, Volume: 37, Issue:1

    Topics: Allergens; Animals; Antibody Specificity; Betula; Cross Reactions; Dose-Response Relationship, Immun

2007