Page last updated: 2024-11-06

pyrrolidine dithiocarbamic acid

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Cross-References

ID SourceID
PubMed CID73343
CHEMBL ID1449651
MeSH IDM0075352

Synonyms (32)

Synonym
ammonium pyrrolidinedithiocarbamate, ~99%
ammonium 1-pyrrolidinedithiocarboxylate
ammonium 1-pyrrolidinyldithiocarbamate
ammonium pyrrolidyldithiocarbamate
nsc-298194
ammonium tetramethylenedithiocarbamate
ai3-36577
pyrrolidine dithiocarbamic acid, ammonium salt
einecs 225-834-4
nsc 298194
pyrrolidinedithiocarbamate (ammonium)
ammonium 1-pyrrolidine dithiocarbamate
CHEMBL1449651
S3633
1-pyrrolidinecarbodithioic acid, ammonium salt (1:1)
AKOS025310603
ammonium 1-pyrrolidinedithiocarbamate
CS-5075
DTXSID8063703
HY-18738
mfcd00012720
ammonium pyrrolidinedithiocarbamate, purum p.a., >=98.0% (nt)
SR-01000076088-1
sr-01000076088
SR-01000076088-3
pyrrolidine-1-carbodithioic acid, ammonia salt
1-pyrrolidinecarbodithioic acid, ammonium salt - cas 5108-96-3
AS-14390
CCG-266316
pyrrolidinedithiocarbamate ammonium;apdc, pdtc
ammonium pyrrolidinedithiocarbamate;apdc;1-pyrrolidinedithiocarboxylic acid ammonium salt;pdtc
pyrrolidinedithiocarbamic acid ammonium salt
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (2)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Replicase polyprotein 1abBetacoronavirus England 1IC50 (µMol)10.00000.00403.43889.5100AID1640022
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2IC50 (µMol)0.21000.00022.45859.9600AID1640021
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Molecular Functions (10)

Processvia Protein(s)Taxonomy
3'-5'-RNA exonuclease activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
RNA-dependent RNA polymerase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
cysteine-type endopeptidase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
mRNA 5'-cap (guanine-N7-)-methyltransferase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
mRNA (nucleoside-2'-O-)-methyltransferase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
mRNA guanylyltransferase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
RNA endonuclease activity, producing 3'-phosphomonoestersReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
ISG15-specific peptidase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
5'-3' RNA helicase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
protein guanylyltransferase activityReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (1)

Processvia Protein(s)Taxonomy
double membrane vesicle viral factory outer membraneReplicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (82)

Assay IDTitleYearJournalArticle
AID401585Inhibition of iNOS production in LPS-activated mouse RAW264.7 cells after 20 hrs2004Journal of natural products, May, Volume: 67, Issue:5
A new antimalarial quassinoid from Simaba orinocensis.
AID401563Cytotoxicity against mouse RAW264.7 cells after 2 days by MTT assay2004Journal of natural products, May, Volume: 67, Issue:5
A new antimalarial quassinoid from Simaba orinocensis.
AID569268Antimicrobial activity against drug-sensitive Escherichia coli JM1092011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID401580Cytotoxicity against human HL60 cells by XTT assay2004Journal of natural products, May, Volume: 67, Issue:5
A new antimalarial quassinoid from Simaba orinocensis.
AID569282Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 122011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569264Antimicrobial activity against drug-sensitive Staphylococcus aureus RN42202011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569281Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 112011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569255Antimycobacterial activity against Mycobacterium tuberculosis H37Rv2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID401582Inhibition of LFA1/ICAM1-mediated adhesion of HL60 cells to CHO-ICAM1 cells2004Journal of natural products, May, Volume: 67, Issue:5
A new antimalarial quassinoid from Simaba orinocensis.
AID569384Antimycobacterial activity against INH, RFP-resistant Mycobacterium tuberculosis isolate 172011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID524791Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID569269Antibacterial activity against drug-sensitive Klebsiella pneumoniae ATCC BAA-17052011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569261Antimicrobial activity against methicillin-resistant Staphylococcus aureus 8732011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569386Antimycobacterial activity against INH, RFP, SM, EB, PAS, LVFX-resistant Mycobacterium tuberculosis isolate 192011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID401583Cytotoxicity against CHO cells transfected with ICAM1 by MTT assay2004Journal of natural products, May, Volume: 67, Issue:5
A new antimalarial quassinoid from Simaba orinocensis.
AID569286Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 162011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569370Antimycobacterial activity against RFP, EB-resistant Mycobacterium tuberculosis isolate 32011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569376Antimycobacterial activity against INH, RFP, KM, LVFX, SPFX, CPFX-resistant Mycobacterium tuberculosis isolate 92011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID1544461Inhibition of TNFalpha-induced NFkappaB activation in human HEK293 cells expressing pGL4.32 [luc2p/NF-kBRE/Hygro] at 80 uM incubated for 2 hrs followed by TNFalpha addition and measured after 5 hrs by luciferase reporter gene assay2019Bioorganic & medicinal chemistry letters, 06-15, Volume: 29, Issue:12
Cynaropicrin and inhibition of NF-κB activation: A structure activity relationship study.
AID569266Antimicrobial activity against AGs-resistant Enterococcus faecalis ATCC 194332011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569271Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 12011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569403Antimycobacterial activity against Mycobacterium bovis BCG assessed as clolony forming unit at 4 ug/ml after 21 days in presence of sucrose2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569257Antimycobacterial activity against Mycobacterium smegmatis JATA 64.012011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569287Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 172011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569379Antimycobacterial activity against INH, RFP, EB-resistant Mycobacterium tuberculosis isolate 122011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569372Antimycobacterial activity against INH, RFP, EB, KM, LVFX, SPFX, CPFX-resistant Mycobacterium tuberculosis isolate 52011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569381Antimycobacterial activity against INH, RFP, EB-resistant Mycobacterium tuberculosis isolate 142011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569259Antimycobacterial activity against Mycobacterium avium subsp. avium ATCC 2529I2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569400Antimycobacterial activity against Mycobacterium bovis BCG assessed as clolony forming unit at 4 ug/ml after 7 days2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID774420Inhibition of LPS-induced NF-kappaB (unknown origin) activation transfected in mouse RAW264.7 cells preincubated for 2 hrs followed by LPS challenge measured after 4 hrs by luciferase reporter gene assay2013Journal of natural products, Oct-25, Volume: 76, Issue:10
Meroterpenoids with diverse ring systems from the sponge-associated fungus Alternaria sp. JJY-32.
AID569290Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 202011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569276Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 62011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569404Antimycobacterial activity against Mycobacterium bovis BCG assessed as clolony forming unit at 4 ug/ml after 7 days in presence of dextrin2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID524790Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID569273Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 32011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569272Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 22011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569260Antimicrobial activity against Staphylococcus aureus2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569401Antimycobacterial activity against Mycobacterium bovis BCG assessed as clolony forming unit at 4 ug/ml after 21 days2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569283Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 132011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID524796Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID569412Antimycobacterial activity against Mycobacterium bovis BCG carrying pMV2612011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569258Antimycobacterial activity against Mycobacterium avium subsp. hominissuis 1042011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569387Antimycobacterial activity against INH, RFP, ETH-resistant Mycobacterium tuberculosis isolate 202011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID401579Inhibition of LFA1/ICAM1-mediated HL60 cell aggregation2004Journal of natural products, May, Volume: 67, Issue:5
A new antimalarial quassinoid from Simaba orinocensis.
AID569385Antimycobacterial activity against INH, RFP, SM, EB, PAS-resistant Mycobacterium tuberculosis isolate 182011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID524794Antiplasmodial activity against Plasmodium falciparum GB4 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID524792Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID401586Specific index, ratio of IC50 for mouse RAW264.7 to IC50 for iNOS production in mouse RAW264.72004Journal of natural products, May, Volume: 67, Issue:5
A new antimalarial quassinoid from Simaba orinocensis.
AID569380Antimycobacterial activity against INH, RFP, SM, EB-resistant Mycobacterium tuberculosis isolate 132011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569402Antimycobacterial activity against Mycobacterium bovis BCG assessed as clolony forming unit at 4 ug/ml after 7 days in presence of sucrose2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569265Antimicrobial activity against methicillin-resistant Staphylococcus aureus MF4902011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569373Antimycobacterial activity against INH, RFP, SM, EB, KM, LVFX, SPFX, CPFX-resistant Mycobacterium tuberculosis isolate 62011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569414Antimycobacterial activity against Mycobacterium bovis BCG carrying pMV261::ethR2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569284Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 142011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569279Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 92011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569292Antimycobacterial activity against INH, RFP, EB, LVFX, SPFX, CPFX-resistant Mycobacterium tuberculosis isolate 22011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569371Antimycobacterial activity against INH, RFP, EB, LVFX, CPFX-resistant Mycobacterium tuberculosis isolate 42011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569256Antimycobacterial activity against Mycobacterium bovis BCG str. Tokyo 1722011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569378Antimycobacterial activity against INH, RFP, EB, KM, LVFX, SPFX, CPFX-resistant Mycobacterium tuberculosis isolate 112011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569263Antimicrobial activity against drug-sensitive Staphylococcus aureus 209PJC-12011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569267Antimicrobial activity against AGs-resistant Enterococcus faecalis ATCC 194342011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569413Antimycobacterial activity against Mycobacterium bovis BCG carrying pMV261::ethA2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569275Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 52011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID524795Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay2009Nature chemical biology, Oct, Volume: 5, Issue:10
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
AID521220Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay2007Nature chemical biology, May, Volume: 3, Issue:5
Chemical genetics reveals a complex functional ground state of neural stem cells.
AID569285Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 152011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569270Antibacterial activity against drug-sensitive Pseudomonas aeruginosa PAO12011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569289Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 192011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569375Antimycobacterial activity against RFP-resistant Mycobacterium tuberculosis isolate 82011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569383Antimycobacterial activity against INH, RFP, SM, EB, KM, PAS, EVM, LVFX-resistant Mycobacterium tuberculosis isolate 162011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569278Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 82011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569280Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 102011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569382Antimycobacterial activity against INH, RFP, EB, LVFX, SPFX, CPFX-resistant Mycobacterium tuberculosis isolate 152011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569274Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 42011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569291Antimycobacterial activity against INH, RFP, EB, LVFX, SPFX, CPFX-resistant Mycobacterium tuberculosis isolate 12011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID657386Inhibition of LPS-induced NFkappaB expression in mouse RAW264.7 cells at 0.1 uM pretreated for 4 hrs before LPS challenge measured after 24 hrs by luciferase reporter gene assay relative to control2012Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9
Pyronepolyene C-glucosides with NF-κB inhibitory and anti-influenza A viral (H1N1) activities from the sponge-associated fungus Epicoccum sp. JJY40.
AID569288Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 182011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569405Antimycobacterial activity against Mycobacterium bovis BCG assessed as clolony forming unit at 4 ug/ml after 21 days in presence of destrin2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569277Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis isolate 72011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569262Antimicrobial activity against Escherichia coli DH5alpha2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569374Antimycobacterial activity against RFP-resistant Mycobacterium tuberculosis isolate 72011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
AID569377Antimycobacterial activity against RFP-resistant Mycobacterium tuberculosis isolate 102011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.51

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.51 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.51)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]