A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform that is encoded in the genome of mouse. [OMA:P42337, PRO:DNx]
PI3-kinase subunit alpha;
PI3K-alpha;
PI3Kalpha;
PtdIns-3-kinase subunit alpha;
EC 2.7.1.137;
EC 2.7.1.153;
Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha;
PtdIns-3-kinase subunit p110-alpha;Research
Bioassay Publications (4)
Timeframe Studies on this Protein(%) All Drugs % pre-1990 0 (0.00) 18.7374 1990's 0 (0.00) 18.2507 2000's 1 (25.00) 29.6817 2010's 3 (75.00) 24.3611 2020's 0 (0.00) 2.80 Compounds (4)
Drugs with Inhibition Measurements
Drug Taxonomy Measurement Average (mM) Bioassay(s) Publication(s) 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one Mus musculus (house mouse) IC50 0.5000 2 2 5-[[(5,6-dimethyl-4-thieno[2,3-d]pyrimidinyl)thio]methyl]-2-furancarboxylic acid methyl ester Mus musculus (house mouse) IC50 100.0000 1 1 zstk474 Mus musculus (house mouse) IC50 0.0086 1 1 pf-04691502 Mus musculus (house mouse) Ki 0.0006 1 1