Page last updated: 2024-08-07 17:13:30
Sterol O-acyltransferase 1
A sterol O-acyltransferase 1 that is encoded in the genome of mouse. [OMA:Q61263, PRO:DNx]
Synonyms
EC 2.3.1.26;
Acyl-coenzyme A:cholesterol acyltransferase 1;
ACAT-1;
Cholesterol acyltransferase 1
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (5)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| lecimibide | Mus musculus (house mouse) | IC50 | 0.9100 | 2 | 2 |
| pd 128042 | Mus musculus (house mouse) | IC50 | 0.3100 | 1 | 1 |
| avasimibe | Mus musculus (house mouse) | IC50 | 0.4700 | 3 | 3 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| gamma-aminobutyric acid | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| gaboxadol | Mus musculus (house mouse) | EC50 | 335.0000 | 1 | 1 |