quinolinic acid has been researched along with Sensitivity and Specificity in 9 studies
Quinolinic Acid: A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
pyridinedicarboxylic acid : Any member of the class of pyridines carrying two carboxy groups.
quinolinic acid : A pyridinedicarboxylic acid that is pyridine substituted by carboxy groups at positions 2 and 3. It is a metabolite of tryptophan.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid was successfully derivatized in water-based samples by monodansylcadaverine, a fluorescence tag, and analysed by high-performance liquid chromatography (HPLC)." | 1.30 | HPLC analysis of quinolinic acid, a NAD biosynthesis intermediate, after fluorescence derivatization in an aqueous matrix. ( Brown, OR; Dang, Y; Xia, C, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Bou Khalil, R | 1 |
| El Khoury, R | 1 |
| Gobbo, OL | 1 |
| Petit, F | 1 |
| Gurden, H | 1 |
| Dhenain, M | 1 |
| Mawatari, K | 1 |
| Oshida, K | 1 |
| Iinuma, F | 1 |
| Watanabe, M | 1 |
| Strauss, I | 1 |
| Williamson, JM | 1 |
| Bertram, EH | 1 |
| Lothman, EW | 1 |
| Fernandez, EJ | 1 |
| Dobbie, MS | 1 |
| Surtees, RA | 1 |
| Xia, C | 1 |
| Dang, Y | 1 |
| Brown, OR | 1 |
| Furlanetto, S | 1 |
| Pinzauti, S | 1 |
| La Porta, E | 1 |
| Chiarugi, A | 1 |
| Mura, P | 1 |
| Orlandini, S | 1 |
| Nicholls, T | 1 |
| Nitsos, I | 1 |
| Smythe, G | 1 |
| Walker, DW | 1 |
1 trial available for quinolinic acid and Sensitivity and Specificity
| Article | Year |
|---|---|
In vivo detection of excitotoxicity by manganese-enhanced MRI: comparison with physiological stimulation.
Topics: Animals; Brain; Contrast Media; Image Enhancement; Magnetic Resonance Imaging; Male; Manganese; Odor | 2012 |
8 other studies available for quinolinic acid and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
δ
Topics: Biomarkers; Depressive Disorder, Major; Heart Rate; Humans; Kynurenine; Quinolinic Acid; Reproducibi | 2021 |
Determination of quinolinic acid by liquid chromatography with fluorimetric detection.
Topics: Chromatography, Liquid; Humans; Indicators and Reagents; Quinolinic Acid; Reference Values; Reproduc | 1996 |
Histological and 1H magnetic resonance spectroscopic imaging analysis of quinolinic acid-induced damage to the rat striatum.
Topics: Animals; Aspartic Acid; Cell Count; Cell Survival; Chromatography, High Pressure Liquid; Corpus Stri | 1997 |
Concentrations of quinolinic acid in cerebrospinal fluid measured by gas chromatography and electron-impact ionisation mass spectrometry. Age-related changes in a paediatric reference population.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Gas Chromatography-Mass Spectrometry; Humans; Infa | 1997 |
HPLC analysis of quinolinic acid, a NAD biosynthesis intermediate, after fluorescence derivatization in an aqueous matrix.
Topics: Cadaverine; Chromatography, High Pressure Liquid; Fluorescent Dyes; NAD; Quinolinic Acid; Sensitivit | 1998 |
Development and validation of a differential pulse polarographic method for quinolinic acid determination in human plasma and urine after solid-phase extraction: a chemometric approach.
Topics: Chemistry Techniques, Analytical; Gas Chromatography-Mass Spectrometry; Humans; Molecular Structure; | 1998 |
Kynurenine production and catabolism in fetal sheep with embolized or nonembolized placentas.
Topics: Animals; Disease Models, Animal; Embolism; Female; Fetal Blood; Fetal Diseases; Fetal Growth Retarda | 2001 |