A protein that is a translation product of the Cyp11b1 gene in rat. [PRO:DNx, UniProtKB:P15393]
CYPXIB1;
Cytochrome P450(11 beta)-DS;
Cytochrome P450C11;
Steroid 11-beta-hydroxylase, CYP11B1;
1.14.15.4
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| cgs 15943 | Rattus norvegicus (Norway rat) | Ki | 0.0044 | 1 | 1 |
| metyrapone | Rattus norvegicus (Norway rat) | IC50 | 4.7357 | 3 | 3 |
| masoprocol | Rattus norvegicus (Norway rat) | IC50 | 30.0000 | 1 | 1 |
| pf 5901 | Rattus norvegicus (Norway rat) | IC50 | 300.0000 | 1 | 1 |
| phenidone | Rattus norvegicus (Norway rat) | IC50 | 3.0000 | 1 | 1 |
| nafazatrom | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| bw-755c | Rattus norvegicus (Norway rat) | IC50 | 5.0000 | 1 | 1 |
| dazoxiben | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 2 | 2 |
| 1-benzyl-1h-indazol-3-ol | Rattus norvegicus (Norway rat) | IC50 | 31.0000 | 1 | 1 |
| 3-indazolinone | Rattus norvegicus (Norway rat) | IC50 | 30.0000 | 1 | 1 |
| uk 34787 | Rattus norvegicus (Norway rat) | IC50 | 2.0000 | 1 | 1 |
| quercetin | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| baicalein | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| osilodrostat | Rattus norvegicus (Norway rat) | IC50 | 0.4950 | 1 | 1 |