[no definition available]
S glycoprotein;
E2;
Peplomer protein
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| carmofur | Betacoronavirus England 1 | IC50 | 1.8200 | 1 | 1 |
| chloroquine | Betacoronavirus England 1 | IC50 | 5.4700 | 1 | 1 |
| chlorpromazine | Betacoronavirus England 1 | IC50 | 11.2400 | 1 | 2 |
| disulfiram | Betacoronavirus England 1 | IC50 | 9.3500 | 1 | 1 |
| ebselen | Betacoronavirus England 1 | IC50 | 0.6700 | 1 | 1 |
| emodin | Betacoronavirus England 1 | IC50 | 10.0000 | 1 | 1 |
| fluphenazine | Betacoronavirus England 1 | IC50 | 11.8000 | 1 | 2 |
| niclosamide | Betacoronavirus England 1 | IC50 | 50.0000 | 1 | 1 |
| promethazine | Betacoronavirus England 1 | IC50 | 13.6450 | 1 | 2 |
| tanshinone ii a | Betacoronavirus England 1 | IC50 | 0.8000 | 1 | 1 |
| 1-methylpropyl-2-imidazolyl disulfide | Betacoronavirus England 1 | IC50 | 21.0000 | 1 | 2 |
| 1-(2-Naphthylmethyl)-2,3-dioxo-indoline-5-carboxamide | Betacoronavirus England 1 | IC50 | 0.3700 | 1 | 1 |
| hirsutanone | Betacoronavirus England 1 | IC50 | 4.1000 | 1 | 1 |
| S-[5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl] 5-(phenylethynyl)furan-2-carbothioate | Betacoronavirus England 1 | IC50 | 3.0000 | 1 | 1 |
| N-(4-Butan-2-ylphenyl)-N-[2-(cyclopentylamino)-2-oxo-1-pyridin-3-ylethyl]furan-2-carboxamide | Betacoronavirus England 1 | IC50 | 18.1000 | 1 | 2 |
| amentoflavone | Betacoronavirus England 1 | IC50 | 8.3000 | 1 | 1 |
| savinin | Betacoronavirus England 1 | IC50 | 25.0000 | 1 | 1 |
| broussochalcone a | Betacoronavirus England 1 | IC50 | 25.6500 | 1 | 2 |
| rupintrivir | Betacoronavirus England 1 | IC50 | 410.0000 | 1 | 2 |
| rupintrivir | Betacoronavirus England 1 | Ki | 10.0000 | 1 | 2 |
| 5-Chloro-3-pyridinyl 2-furoate | Betacoronavirus England 1 | IC50 | 0.0600 | 1 | 1 |
| np 031112 | Betacoronavirus England 1 | IC50 | 1.5500 | 1 | 1 |
| Benzotriazol-1-yl 1H-indole-5-carboxylate | Betacoronavirus England 1 | Ki | 0.0075 | 1 | 1 |
| 5-Chloropyridin-3-yl 5-(4-chlorophenyl)furan-2-carboxylate | Betacoronavirus England 1 | IC50 | 0.0630 | 1 | 1 |
| (5-Chloropyridin-3-yl) 1H-indole-5-carboxylate | Betacoronavirus England 1 | IC50 | 0.3100 | 1 | 1 |
| 5-Chloropyridin-3-yl 1H-indole-2-carboxylate | Betacoronavirus England 1 | IC50 | 0.0650 | 1 | 1 |
| GRL-0617 | Betacoronavirus England 1 | IC50 | 0.6000 | 1 | 1 |
| (5-Chloropyridin-3-yl) 1H-indole-4-carboxylate | Betacoronavirus England 1 | IC50 | 0.0300 | 1 | 1 |
| KOM70144 | Betacoronavirus England 1 | IC50 | 0.5600 | 1 | 1 |
| N-[(1R)-2-(tert-butylamino)-2-oxo-1-(3-pyridinyl)ethyl]-N-(4-tert-butylphenyl)-2-furancarboxamide | Betacoronavirus England 1 | IC50 | 1.5000 | 1 | 1 |
| N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide | Betacoronavirus England 1 | IC50 | 0.0500 | 1 | 1 |
| 3-fluoro-Nalpha-(1H-indol-2-ylcarbonyl)-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide | Betacoronavirus England 1 | IC50 | 0.0400 | 1 | 1 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| amodiaquine | Betacoronavirus England 1 | EC50 | 3.1933 | 1 | 3 |
| astemizole | Betacoronavirus England 1 | EC50 | 5.2350 | 1 | 2 |
| camostat | Betacoronavirus England 1 | EC50 | 10.0000 | 1 | 2 |
| chloroquine | Betacoronavirus England 1 | EC50 | 5.3333 | 1 | 6 |
| chlorpromazine | Betacoronavirus England 1 | EC50 | 7.7360 | 1 | 5 |
| clomipramine | Betacoronavirus England 1 | EC50 | 11.2800 | 1 | 2 |
| ebselen | Betacoronavirus England 1 | EC50 | 4.6700 | 1 | 1 |
| emodin | Betacoronavirus England 1 | EC50 | 200.0000 | 1 | 2 |
| fluphenazine | Betacoronavirus England 1 | EC50 | 16.2400 | 1 | 3 |
| fluspirilene | Betacoronavirus England 1 | EC50 | 6.7150 | 1 | 2 |
| hydroxychloroquine | Betacoronavirus England 1 | EC50 | 5.6567 | 1 | 3 |
| hydroxyzine | Betacoronavirus England 1 | EC50 | 14.4000 | 1 | 1 |
| loperamide | Betacoronavirus England 1 | EC50 | 5.0800 | 1 | 5 |
| mefloquine hydrochloride | Betacoronavirus England 1 | EC50 | 11.4800 | 1 | 2 |
| promethazine | Betacoronavirus England 1 | EC50 | 9.6700 | 1 | 2 |
| imatinib | Betacoronavirus England 1 | EC50 | 12.5000 | 1 | 3 |
| thiethylperazine | Betacoronavirus England 1 | EC50 | 7.8600 | 1 | 1 |
| triflupromazine | Betacoronavirus England 1 | EC50 | 6.0700 | 1 | 2 |
| cycloheximide | Betacoronavirus England 1 | EC50 | 0.1145 | 1 | 2 |
| chlorphenoxamine | Betacoronavirus England 1 | EC50 | 16.3350 | 1 | 2 |
| triparanol | Betacoronavirus England 1 | EC50 | 5.2800 | 1 | 1 |
| emetine | Betacoronavirus England 1 | EC50 | 0.0325 | 1 | 2 |
| acetophenazine | Betacoronavirus England 1 | EC50 | 23.6000 | 1 | 1 |
| ribavirin | Betacoronavirus England 1 | EC50 | 109.5000 | 1 | 1 |
| gemcitabine | Betacoronavirus England 1 | EC50 | 3.0800 | 1 | 2 |
| methotrimeprazine | Betacoronavirus England 1 | EC50 | 2.5000 | 1 | 1 |
| lopinavir | Betacoronavirus England 1 | EC50 | 12.8200 | 1 | 5 |
| nutlin 3 | Betacoronavirus England 1 | EC50 | 36.9000 | 1 | 1 |
| anisomycin | Betacoronavirus England 1 | EC50 | 0.0965 | 1 | 2 |
| homoharringtonine | Betacoronavirus England 1 | EC50 | 0.0710 | 1 | 1 |
| terconazole | Betacoronavirus England 1 | EC50 | 13.7600 | 1 | 2 |
| thiothixene | Betacoronavirus England 1 | EC50 | 7.3000 | 1 | 2 |
| benztropine | Betacoronavirus England 1 | EC50 | 19.1150 | 1 | 2 |
| tamoxifen | Betacoronavirus England 1 | EC50 | 51.4950 | 1 | 2 |
| toremifene | Betacoronavirus England 1 | EC50 | 12.4350 | 1 | 2 |
| dasatinib | Betacoronavirus England 1 | EC50 | 0.0325 | 1 | 2 |
| quercetin | Betacoronavirus England 1 | EC50 | 83.4000 | 1 | 1 |
| luteolin | Betacoronavirus England 1 | EC50 | 10.6000 | 1 | 1 |
| dothiepin hydrochloride | Betacoronavirus England 1 | EC50 | 3.4000 | 1 | 1 |
| sotrastaurin | Betacoronavirus England 1 | EC50 | 9.7000 | 1 | 1 |
| saracatinib | Betacoronavirus England 1 | EC50 | 2.9000 | 1 | 1 |
| (5-Chloropyridin-3-yl) 1H-indole-5-carboxylate | Betacoronavirus England 1 | EC50 | 24.0000 | 1 | 1 |
| (5-Chloropyridin-3-yl) 1H-indole-4-carboxylate | Betacoronavirus England 1 | EC50 | 6.9000 | 1 | 1 |
| s 8932 | Betacoronavirus England 1 | EC50 | 0.7700 | 1 | 1 |
| N-[(2S)-3-cyclohexyl-1-oxo-1-({(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)propan-2-yl]-1H-indole-2-carboxamide | Betacoronavirus England 1 | EC50 | 0.4200 | 1 | 1 |
| molnupiravir | Betacoronavirus England 1 | EC50 | 0.1540 | 1 | 1 |
| 3-fluoro-Nalpha-(1H-indol-2-ylcarbonyl)-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide | Betacoronavirus England 1 | EC50 | 0.3300 | 1 | 1 |