Compounds > 5-bromo-2,3-dimethoxy-n-((1-(4-fluorobenzyl)-2-pyrrolidinyl)methyl)benzamide
Page last updated: 2024-12-07

5-bromo-2,3-dimethoxy-n-((1-(4-fluorobenzyl)-2-pyrrolidinyl)methyl)benzamide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

5-bromo-2,3-dimethoxy-N-((1-(4-fluorobenzyl)-2-pyrrolidinyl)methyl)benzamide: structure given in first source; a selective dopamine D2 receptor ligand; tritiated form may prove useful in positron emission tomography of the brain in vivo [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID129499
SCHEMBL ID3361739
MeSH IDM0198067

Synonyms (11)

Synonym
L004522
5-bromo-n-[[1-[(4-fluorophenyl)methyl]pyrrolidin-2-yl]methyl]-2,3-dimethoxybenzamide
ncq-115
5-bromo-2,3-dimethoxy-n-((1-((2,5-3h)-4-fluorobenzyl)-2-pyrrolidinyl)methyl)benzamide
5-bromo-2,3-dimethoxy-n-((1-(4-fluorobenzyl)-2-pyrrolidinyl)methyl)benzamide
benzamide, 5-bromo-n-((1-((4-fluorophenyl)methyl)-2-pyrrolidinyl)methyl)-2,3-dimethoxy-
107188-68-1
SCHEMBL3361739
5-bromo-n-{[1-(4-fluorobenzyl)pyrrolidin-2-yl]methyl}-2,3-dimethoxybenzamide
DTXSID30910249
5-bromo-n-({1-[(4-fluorophenyl)methyl]pyrrolidin-2-yl}methyl)-2,3-dimethoxybenzene-1-carboximidic acid
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.66 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (20.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
spiperone
Spiperone: A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.. spiperone : An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively.		1.9710aromatic ketone;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound		alpha-adrenergic antagonist;
antipsychotic agent;
dopaminergic antagonist;
psychotropic drug;
serotonergic antagonist
raclopride
Raclopride: A substituted benzamide that has antipsychotic properties. It is a dopamine D2 receptor (see RECEPTORS, DOPAMINE D2) antagonist.		3.4820salicylamides
ncq 298
NCQ 298: structure given in first source		3.0810
ConditionIndicatedRelationship StrengthStudiesTrials
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		01.9810