| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Bone Loss, Osteoclastic
[description not available] | 0 | 9.19 | 20 | 2 |
Infection, Toxoplasma gondii
[description not available] | 0 | 2.02 | 1 | 0 |
Toxoplasmosis
The acquired form of infection by Toxoplasma gondii in animals and man. | 0 | 2.02 | 1 | 0 |
Age-Related Osteoporosis
[description not available] | 0 | 11.1 | 34 | 13 |
Osteoporosis
Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis. | 1 | 13.1 | 34 | 13 |
DRESS Syndrome
[description not available] | 0 | 2.31 | 1 | 0 |
Bone Fractures
[description not available] | 0 | 7.72 | 7 | 2 |
Low Bone Density
[description not available] | 0 | 4.71 | 6 | 1 |
Breast Cancer
[description not available] | 0 | 2.51 | 2 | 0 |
Bone Diseases, Metabolic
Diseases that affect the METABOLIC PROCESSES of BONE TISSUE. | 0 | 4.71 | 6 | 1 |
Breast Neoplasms
Tumors or cancer of the human BREAST. | 0 | 2.51 | 2 | 0 |
Fractures, Bone
Breaks in bones. | 0 | 7.72 | 7 | 2 |
Hangman Fracture
[description not available] | 0 | 10.35 | 13 | 7 |
Spinal Fractures
Broken bones in the vertebral column. | 0 | 10.35 | 13 | 7 |
Cancer of Prostate
[description not available] | 0 | 4.14 | 3 | 1 |
Prostatic Neoplasms
Tumors or cancer of the PROSTATE. | 0 | 4.14 | 3 | 1 |
Bone Loss, Perimenopausal
[description not available] | 0 | 11.09 | 16 | 8 |
Osteoporosis, Postmenopausal
Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency. | 1 | 13.09 | 16 | 8 |
Palmoplantaris Pustulosis
[description not available] | 0 | 2.25 | 1 | 0 |
Psoriasis
A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis. | 0 | 2.25 | 1 | 0 |
Chondrosarcoma
A slowly growing malignant neoplasm derived from cartilage cells, occurring most frequently in pelvic bones or near the ends of long bones, in middle-aged and old people. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion or in patients with ENCHONDROMATOSIS. (Stedman, 25th ed) | 0 | 2.25 | 1 | 0 |
Spinal Neoplasms
New abnormal growth of tissue in the SPINE. | 0 | 2.25 | 1 | 0 |
Osteoporotic Fractures
Breaks in bones resulting from low bone mass and microarchitectural deterioration characteristic of OSTEOPOROSIS. | 0 | 6.59 | 8 | 6 |
Acute Kidney Failure
[description not available] | 0 | 2.57 | 2 | 0 |
Focal Segmental Glomerulosclerosis
[description not available] | 0 | 2.57 | 2 | 0 |
Glomerulosclerosis, Focal Segmental
A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE. | 0 | 2.57 | 2 | 0 |
Nephrotic Syndrome
A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction. | 0 | 2.57 | 2 | 0 |
Proteinuria
The presence of proteins in the urine, an indicator of KIDNEY DISEASES. | 0 | 2.41 | 1 | 0 |
Acute Kidney Injury
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions. | 0 | 2.57 | 2 | 0 |
Rheumatoid Arthritis
[description not available] | 0 | 4.24 | 3 | 1 |
Arthritis, Rheumatoid
A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. | 0 | 4.24 | 3 | 1 |
Disease Exacerbation
[description not available] | 0 | 2.54 | 2 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 4.83 | 12 | 0 |
Scoliosis
An appreciable lateral deviation in the normally straight vertical line of the spine. (Dorland, 27th ed) | 0 | 2.17 | 1 | 0 |
Pain, Chronic
[description not available] | 0 | 2.17 | 1 | 0 |
Chronic Pain
Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain. | 0 | 2.17 | 1 | 0 |
Mouth Ulcer
[description not available] | 0 | 2.21 | 1 | 0 |
Acute Confusional Senile Dementia
[description not available] | 0 | 3.92 | 2 | 1 |
Alzheimer Disease
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) | 0 | 3.92 | 2 | 1 |
Oral Ulcer
A loss of mucous substance of the mouth showing local excavation of the surface, resulting from the sloughing of inflammatory necrotic tissue. It is the result of a variety of causes, e.g., denture irritation, aphthous stomatitis (STOMATITIS, APHTHOUS); NOMA; necrotizing gingivitis (GINGIVITIS, NECROTIZING ULCERATIVE); TOOTHBRUSHING; and various irritants. (From Jablonski, Dictionary of Dentistry, 1992, p842) | 0 | 2.21 | 1 | 0 |
Aging
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. | 0 | 3 | 1 | 0 |
Acute Pain
Intensely discomforting, distressful, or agonizing sensation associated with trauma or disease, with well-defined location, character, and timing. | 0 | 2.08 | 1 | 0 |
Aseptic Necrosis of Bone
[description not available] | 0 | 2.08 | 1 | 0 |
Osteonecrosis
Death of a bone or part of a bone, either atraumatic or posttraumatic. | 0 | 2.08 | 1 | 0 |
Atherogenesis
[description not available] | 0 | 3.48 | 1 | 1 |
Atherosclerosis
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA. | 0 | 3.48 | 1 | 1 |
Cholera Infantum
[description not available] | 0 | 2.1 | 1 | 0 |
Low Back Ache
[description not available] | 0 | 3.91 | 2 | 1 |
Low Back Pain
Acute or chronic pain in the lumbar or sacral regions, which may be associated with musculo-ligamentous SPRAINS AND STRAINS; INTERVERTEBRAL DISK DISPLACEMENT; and other conditions. | 0 | 3.91 | 2 | 1 |
Bone Cancer
[description not available] | 0 | 3.73 | 10 | 0 |
Adenocarcinoma Of Kidney
[description not available] | 0 | 2.74 | 3 | 0 |
Cancer of Kidney
[description not available] | 0 | 2.95 | 4 | 0 |
Bone Neoplasms
Tumors or cancer located in bone tissue or specific BONES. | 0 | 3.73 | 10 | 0 |
Carcinoma, Renal Cell
A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma. | 0 | 2.74 | 3 | 0 |
Kidney Neoplasms
Tumors or cancers of the KIDNEY. | 0 | 2.95 | 4 | 0 |
Bisphosphonate Osteonecrosis
[description not available] | 0 | 2.11 | 1 | 0 |
Fracture, Pathologic
[description not available] | 0 | 4.68 | 4 | 0 |
Mandibular Fractures
Fractures of the lower jaw. | 0 | 2.11 | 1 | 0 |
Dental Fistula
An abnormal passage in the oral cavity on the gingiva. | 0 | 2.11 | 1 | 0 |
Mandibular Diseases
Diseases involving the MANDIBLE. | 0 | 2.11 | 1 | 0 |
Fibroid
[description not available] | 0 | 2.13 | 1 | 0 |
Cancer of the Uterus
[description not available] | 0 | 2.13 | 1 | 0 |
Leiomyoma
A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues. | 0 | 2.13 | 1 | 0 |
Uterine Neoplasms
Tumors or cancer of the UTERUS. | 0 | 2.13 | 1 | 0 |
Adenomyosis
The extension of endometrial tissue (ENDOMETRIUM) into the MYOMETRIUM. It usually occurs in women in their reproductive years and may result in a diffusely enlarged uterus with ectopic and benign endometrial glands and stroma. | 0 | 2.13 | 1 | 0 |
Femoral Fractures
Fractures of the femur. | 0 | 2.15 | 1 | 0 |
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 3.12 | 5 | 0 |
Benign Neoplasms, Brain
[description not available] | 0 | 2.13 | 1 | 0 |
Astrocytoma, Grade IV
[description not available] | 0 | 2.13 | 1 | 0 |
Brain Neoplasms
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 2.13 | 1 | 0 |
Glioblastoma
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 0 | 2.13 | 1 | 0 |
Carcinoma, Non-Small Cell Lung
[description not available] | 0 | 2.47 | 2 | 0 |
Cancer of Lung
[description not available] | 0 | 3.13 | 5 | 0 |
Carcinoma, Non-Small-Cell Lung
A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy. | 0 | 2.47 | 2 | 0 |
Lung Neoplasms
Tumors or cancer of the LUNG. | 0 | 3.13 | 5 | 0 |
Ache
[description not available] | 0 | 2.04 | 1 | 0 |
Pain
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS. | 0 | 2.04 | 1 | 0 |
B16 Melanoma
[description not available] | 0 | 2.44 | 2 | 0 |
Metastase
[description not available] | 0 | 2.74 | 3 | 0 |
Neoplasm Metastasis
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. | 0 | 2.74 | 3 | 0 |
Gastric Ulcer
[description not available] | 0 | 2.06 | 1 | 0 |
Stomach Ulcer
Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS). | 0 | 2.06 | 1 | 0 |
Osteogenic Sarcoma
[description not available] | 0 | 2.74 | 3 | 0 |
Invasiveness, Neoplasm
[description not available] | 0 | 2.95 | 4 | 0 |
Osteosarcoma
A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed) | 0 | 2.74 | 3 | 0 |
Back Ache
[description not available] | 0 | 4.39 | 1 | 1 |
Back Pain
Acute or chronic pain located in the posterior regions of the THORAX; LUMBOSACRAL REGION; or the adjacent regions. | 0 | 4.39 | 1 | 1 |
Hematologic Malignancies
[description not available] | 0 | 2.44 | 2 | 0 |
Hematologic Neoplasms
Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES. | 0 | 2.44 | 2 | 0 |
Bone Demineralization, Pathologic
Decrease, loss, or removal of the mineral constituents of bones. Temporary loss of bone mineral content is especially associated with space flight, weightlessness, and extended immobilization. OSTEOPOROSIS is permanent, includes reduction of total bone mass, and is associated with increased rate of fractures. CALCIFICATION, PHYSIOLOGIC is the process of bone remineralizing. (From Dorland, 27th ed; Stedman, 25th ed; Nicogossian, Space Physiology and Medicine, 2d ed, pp327-33) | 0 | 2.68 | 3 | 0 |
Carcinoma, Oat Cell
[description not available] | 0 | 2.42 | 2 | 0 |
Cancer of Liver
[description not available] | 0 | 2.42 | 2 | 0 |
Lymph Node Metastasis
[description not available] | 0 | 2.42 | 2 | 0 |
Osteolysis
Dissolution of bone that particularly involves the removal or loss of calcium. | 0 | 2.41 | 2 | 0 |
Bare Lymphocyte Syndrome
[description not available] | 0 | 2.01 | 1 | 0 |
Liver Neoplasms
Tumors or cancer of the LIVER. | 0 | 2.42 | 2 | 0 |
Severe Combined Immunodeficiency
Group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an X-linked or autosomal recessive defect. Mutations occurring in many different genes cause human Severe Combined Immunodeficiency (SCID). | 0 | 2.01 | 1 | 0 |
Carcinoma, Small Cell
An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7) | 0 | 2.42 | 2 | 0 |
Kahler Disease
[description not available] | 0 | 2.93 | 4 | 0 |
Multiple Myeloma
A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY. | 0 | 2.93 | 4 | 0 |
Adjuvant Arthritis
[description not available] | 0 | 2.43 | 2 | 0 |
Angiogenesis, Pathologic
[description not available] | 0 | 2.02 | 1 | 0 |
Cancer of Skin
[description not available] | 0 | 2.02 | 1 | 0 |
Skin Neoplasms
Tumors or cancer of the SKIN. | 0 | 2.02 | 1 | 0 |
Benign Neoplasms
[description not available] | 0 | 2.02 | 1 | 0 |
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 2.02 | 1 | 0 |
Leucocythaemia
[description not available] | 0 | 2.02 | 1 | 0 |
Leukemia
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) | 0 | 2.02 | 1 | 0 |
Carcinoma, Epidermoid
[description not available] | 0 | 2.02 | 1 | 0 |
Cancer of Mouth
[description not available] | 0 | 2.02 | 1 | 0 |
Carcinoma, Squamous Cell
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) | 0 | 2.02 | 1 | 0 |
Mouth Neoplasms
Tumors or cancer of the MOUTH. | 0 | 2.02 | 1 | 0 |
Bladder Cancer
[description not available] | 0 | 2.43 | 2 | 0 |
Urinary Bladder Neoplasms
Tumors or cancer of the URINARY BLADDER. | 0 | 2.43 | 2 | 0 |
Carcinoma, Transitional Cell
A malignant neoplasm derived from TRANSITIONAL EPITHELIAL CELLS, occurring chiefly in the URINARY BLADDER; URETERS; or RENAL PELVIS. | 0 | 2.02 | 1 | 0 |
Diabetic Retinopathy
Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION. | 0 | 2.03 | 1 | 0 |
Sarcoma, Epithelioid
[description not available] | 0 | 2.03 | 1 | 0 |
Sarcoma
A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant. | 0 | 2.03 | 1 | 0 |
Ewing Sarcoma
[description not available] | 0 | 2.04 | 1 | 0 |
Sarcoma, Ewing
A malignant tumor of the bone which always arises in the medullary tissue, occurring more often in cylindrical bones. The tumor occurs usually before the age of 20, about twice as frequently in males as in females. | 0 | 2.04 | 1 | 0 |
Carcinoma, Anaplastic
[description not available] | 0 | 2.04 | 1 | 0 |
Carcinoma
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer. | 0 | 2.04 | 1 | 0 |
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 1.98 | 1 | 0 |
Milk-Alkali Syndrome
[description not available] | 0 | 2 | 1 | 0 |
Fibrosarcoma
A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed) | 0 | 2 | 1 | 0 |
Hypercalcemia
Abnormally high level of calcium in the blood. | 0 | 2 | 1 | 0 |