adenine has been researched along with Sensitivity and Specificity in 146 studies
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Altered cyclin D1 (CD1), a cell cycle regulator, may play an important role in imparting aggressive nature to esophageal adenocarcinoma (EAC)." | 7.74 | Cyclin D1 guanine/adenine 870 polymorphism with altered protein expression is associated with genomic instability and aggressive clinical biology of esophageal adenocarcinoma. ( Ajani, JA; Chao, CK; Correa, A; Ensor, J; Hittelman, WN; Izzo, JG; Luthra, R; Pan, J; Swisher, SG; Wu, TT; Wu, X, 2007) |
| "The nucleotide analog adefovir dipivoxil (ADV) is an effective antiviral treatment for chronic hepatitis B virus (HBV) infection, with resistance to ADV estimated to occur less frequently than resistance to lamivudine treatment." | 7.73 | Detection of rtN236T and rtA181V/T mutations associated with resistance to adefovir dipivoxil in samples from patients with chronic hepatitis B virus infection by the INNO-LiPA HBV DR line probe assay (version 2). ( Borlang, J; Giles, E; Heathcote, EJ; Osiowy, C; Villeneuve, JP, 2006) |
| "A group of 39 patients with malignant melanoma were treated with dacarbazine 1 g/m(2) i." | 7.70 | Evaluation of the alkaline comet assay and urinary 3-methyladenine excretion for monitoring DNA damage in melanoma patients treated with dacarbazine and tamoxifen. ( Braybrooke, JP; Crawley, JE; Harris, AL; Houlbrook, S; O'Byrne, KJ; Propper, DJ; Shuker, DE; Stratford, IJ; Talbot, DC, 2000) |
| "An adenine-to-guanine mutation at nucleotide position (np) 3243 in the mitochondrial tRNALeu(UUR) gene is closely associated with various clinical phenotypes of diabetes mellitus." | 5.08 | New sensitive method for the detection of the A3243G mutation of human mitochondrial deoxyribonucleic acid in diabetes mellitus patients by ligation-mediated polymerase chain reaction. ( Hamasaki, N; Iwase, M; Kang, D; Kinoshita, S; Urata, M; Wakiyama, M; Yoneda, M, 1998) |
| "Pre-exposure prophylaxis (PrEP) with tenofovir and emtricitabine effectively prevents new HIV infections." | 3.79 | Cost-effectiveness of pre-exposure prophylaxis (PrEP) in preventing HIV-1 infections in rural Zambia: a modeling study. ( Baltussen, R; Boucher, CA; Nichols, BE; Nouwen, JL; Sloot, PM; Thuma, PE; van de Vijver, DA; van de Wijgert, J; van Dijk, JH, 2013) |
| "Altered cyclin D1 (CD1), a cell cycle regulator, may play an important role in imparting aggressive nature to esophageal adenocarcinoma (EAC)." | 3.74 | Cyclin D1 guanine/adenine 870 polymorphism with altered protein expression is associated with genomic instability and aggressive clinical biology of esophageal adenocarcinoma. ( Ajani, JA; Chao, CK; Correa, A; Ensor, J; Hittelman, WN; Izzo, JG; Luthra, R; Pan, J; Swisher, SG; Wu, TT; Wu, X, 2007) |
| "The nucleotide analog adefovir dipivoxil (ADV) is an effective antiviral treatment for chronic hepatitis B virus (HBV) infection, with resistance to ADV estimated to occur less frequently than resistance to lamivudine treatment." | 3.73 | Detection of rtN236T and rtA181V/T mutations associated with resistance to adefovir dipivoxil in samples from patients with chronic hepatitis B virus infection by the INNO-LiPA HBV DR line probe assay (version 2). ( Borlang, J; Giles, E; Heathcote, EJ; Osiowy, C; Villeneuve, JP, 2006) |
| "A group of 39 patients with malignant melanoma were treated with dacarbazine 1 g/m(2) i." | 3.70 | Evaluation of the alkaline comet assay and urinary 3-methyladenine excretion for monitoring DNA damage in melanoma patients treated with dacarbazine and tamoxifen. ( Braybrooke, JP; Crawley, JE; Harris, AL; Houlbrook, S; O'Byrne, KJ; Propper, DJ; Shuker, DE; Stratford, IJ; Talbot, DC, 2000) |
| "Patients with chronic lymphocytic leukemia (CLL) that develop resistance to Bruton tyrosine kinase (BTK) inhibitors are typically positive for mutations in BTK or phospholipase c gamma 2 (PLCγ2)." | 1.46 | Using high-sensitivity sequencing for the detection of mutations in BTK and PLCγ2 genes in cellular and cell-free DNA and correlation with progression in patients treated with BTK inhibitors. ( Ahn, I; Albitar, A; Albitar, M; DeDios, I; Estella, J; Farooqui, M; Ma, W; Wiestner, A, 2017) |
| " The proposed assay method was found to be applicable to a pharmacokinetic study in human male volunteers." | 1.38 | A novel LC-MS/MS method for simultaneous quantification of tenofovir and lamivudine in human plasma and its application to a pharmacokinetic study. ( Burugula, L; Inamadugu, JK; J V L N, SR; Matta, MK; Pilli, NR, 2012) |
| " The quantitation method was successfully applied for simultaneous estimation of IC87114, RFM and RFN in a pharmacokinetic drug-drug interaction study in Wistar rats." | 1.38 | Simultaneous quantitation of IC87114, roflumilast and its active metabolite roflumilast N-oxide in plasma by LC-MS/MS: application for a pharmacokinetic study. ( Mukkanti, K; Thappali, SR; Vakkalanka, SK; Varanasi, KV; Veeraraghavan, S, 2012) |
| "Abacavir-based treatment without HLA-B*5701 testing resulted in a projected 30." | 1.35 | The cost-effectiveness of HLA-B*5701 genetic screening to guide initial antiretroviral therapy for HIV. ( Freedberg, KA; Losina, E; Sax, PE; Schackman, BR; Scott, CA; Walensky, RP, 2008) |
| " A new combination therapy consisting of the TFV pro-drug (300 mg) and another reverse transcriptase inhibitor, emtricitabine (FTC, 200 mg) has become available in a convenient once-daily dosage form (Truvada)." | 1.35 | The simultaneous assay of tenofovir and emtricitabine in plasma using LC/MS/MS and isotopically labeled internal standards. ( Bushman, L; Delahunty, T; Fletcher, CV; Robbins, B, 2009) |
| " Alkoxyalkyl esters of CDV have an increased oral bioavailability and are more active against orthopoxviruses than the parent compounds." | 1.34 | In vitro evaluation of the anti-orf virus activity of alkoxyalkyl esters of CDV, cCDV and (S)-HPMPA. ( Andrei, G; Beadle, JR; Dal Pozzo, F; De Clercq, E; Hostetler, KY; Lebeau, I; Snoeck, R, 2007) |
| "Success in antiviral therapy for chronic hepatitis B is supported by highly sensitive PCR-based assays for hepatitis B virus (HBV) DNA." | 1.34 | COBAS AmpliPrep-COBAS TaqMan hepatitis B virus (HBV) test: a novel automated real-time PCR assay for quantification of HBV DNA in plasma. ( Allice, T; Cerutti, F; Colucci, G; Franchello, A; Gabella, S; Ghisetti, V; Marzano, A; Pittaluga, F; Varetto, S, 2007) |
| "The adenine nucleobases were released by acid or nuclease from Au nanoparticles bound on microtiter plates." | 1.34 | Ultrasensitive electrochemical detection of proteins by amplification of aptamer-nanoparticle bio bar codes. ( Cao, Y; He, P; Li, D; Shen, L, 2007) |
| "Treatment options for chronic hepatitis B virus (HBV) infection have disparate risks and benefits." | 1.33 | Treatment alternatives for chronic hepatitis B virus infection: a cost-effectiveness analysis. ( Dulai, GS; Farid, M; Gralnek, IM; Kanwal, F; Martin, P; Spiegel, BM, 2005) |
| "Adefovir was stable under routine laboratory conditions." | 1.33 | Determination of adefovir in human plasma by liquid chromatography/tandem mass spectrometry: application to a pharmacokinetic study. ( Bi, HC; Chen, X; Huang, M; Zhong, GP; Zhou, S, 2005) |
| "Fluorene and pyrene were separated in a microcolumn and detected in a capillary (50-microm inner diameter) with 150 times higher sensitivity than a spectrophotometric method." | 1.33 | UV excitation thermal lens microscope for sensitive and nonlabeled detection of nonfluorescent molecules. ( Hibara, A; Hiki, S; Kitamori, T; Mawatari, K; Tokeshi, M, 2006) |
| "Adenosine is suggested to be a potential candidate because of its high uptake and rapid intracellular sequestration." | 1.32 | Tracer adenosine: a novel myocardial flow marker. ( Deussen, A; Lauer, T; Loncar, R, 2003) |
| "Styrene is an extensively used industrial chemical that has been classified as a possible human carcinogen." | 1.31 | Identification of 1-adenine DNA adducts in workers occupationally exposed to styrene. ( Hemminki, K; Koskinen, M; Vodicka, P, 2001) |
| "4." | 1.29 | Pharmacological selectivity of the cloned human P2U-purinoceptor: potent activation by diadenosine tetraphosphate. ( Boucher, RC; Harden, TK; Lazarowski, ER; Stutts, MJ; Watt, WC, 1995) |
| "We studied 27 patients with untreated Graves' disease, 10 with Graves' disease complicated by ophthalmopathy (all on antithyroid medication), 11 with Hashimoto's thyroiditis, five with multinodular goitre, one with thyroid carcinoma, 23 with type 1 diabetes mellitus, 19 with other autoimmune diseases and 10 controls." | 1.28 | Measurement of thyroid-stimulating immunoglobulins by incorporation of tritiated-adenine into intact FRTL-5 cells: a viable alternative to radioimmunoassay for the measurement of cAMP. ( Colman, PG; Frauman, AG; Leedman, PJ; Michelangeli, VP, 1992) |
| "Anti-adenosine antibodies were produced in rabbits immunized with N6-carboxymethyladenosine conjugated to methyl albumin." | 1.28 | The precise radioimmunoassay of adenosine: minimization of sample collection artifacts and immunocrossreactivity. ( Ayers, CR; Feldman, MD; Iflah, S; Linden, J; Patel, A; Ripley, ML; Taylor, HE; Woodward, EB, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 26 (17.81) | 18.2507 |
| 2000's | 79 (54.11) | 29.6817 |
| 2010's | 39 (26.71) | 24.3611 |
| 2020's | 2 (1.37) | 2.80 |
| Authors | Studies |
|---|---|
| Higgins, M | 1 |
| Stringer, OW | 1 |
| Ward, D | 1 |
| Andrews, JM | 1 |
| Forrest, MS | 1 |
| Campino, S | 1 |
| Clark, TG | 1 |
| Raćkowska, E | 1 |
| Bobrowska-Korczak, B | 1 |
| Giebułtowicz, J | 1 |
| Beć, KB | 1 |
| Grabska, J | 1 |
| Ozaki, Y | 1 |
| Czarnecki, MA | 1 |
| Huck, CW | 1 |
| Meitlis, I | 1 |
| Allenspach, EJ | 1 |
| Bauman, BM | 1 |
| Phan, IQ | 1 |
| Dabbah, G | 1 |
| Schmitt, EG | 1 |
| Camp, ND | 1 |
| Torgerson, TR | 1 |
| Nickerson, DA | 1 |
| Bamshad, MJ | 1 |
| Hagin, D | 1 |
| Luthers, CR | 1 |
| Stinson, JR | 1 |
| Gray, J | 1 |
| Lundgren, I | 1 |
| Church, JA | 1 |
| Butte, MJ | 1 |
| Jordan, MB | 1 |
| Aceves, SS | 1 |
| Schwartz, DM | 1 |
| Milner, JD | 1 |
| Schuval, S | 1 |
| Skoda-Smith, S | 1 |
| Cooper, MA | 1 |
| Starita, LM | 1 |
| Rawlings, DJ | 1 |
| Snow, AL | 1 |
| James, RG | 1 |
| Rood, JJM | 1 |
| Dormans, PJA | 1 |
| van Haren, MJ | 1 |
| Schellens, JHM | 1 |
| Beijnen, JH | 4 |
| Sparidans, RW | 3 |
| Liu, Z | 1 |
| Lu, Z | 1 |
| Yang, G | 1 |
| Huang, S | 1 |
| Li, G | 1 |
| Feng, S | 1 |
| Liu, Y | 2 |
| Li, J | 1 |
| Yu, W | 1 |
| Zhang, Y | 1 |
| Chen, J | 1 |
| Sun, Q | 1 |
| Huang, X | 1 |
| Lee, HK | 1 |
| Willi, M | 1 |
| Miller, SM | 1 |
| Kim, S | 1 |
| Liu, C | 1 |
| Liu, DR | 1 |
| Hennighausen, L | 1 |
| Liang, P | 1 |
| Xie, X | 1 |
| Zhi, S | 1 |
| Sun, H | 1 |
| Zhang, X | 2 |
| Chen, Y | 2 |
| Xiong, Y | 1 |
| Ma, W | 2 |
| Liu, D | 1 |
| Huang, J | 1 |
| Songyang, Z | 1 |
| Kromdijk, W | 1 |
| Pereira, SA | 1 |
| Rosing, H | 1 |
| Mulder, JW | 1 |
| Huitema, AD | 1 |
| Nishijima, T | 1 |
| Shimbo, T | 1 |
| Komatsu, H | 1 |
| Takano, M | 1 |
| Tanuma, J | 1 |
| Tsukada, K | 1 |
| Teruya, K | 1 |
| Gatanaga, H | 1 |
| Kikuchi, Y | 1 |
| Oka, S | 1 |
| Hotta, MT | 1 |
| Broderick, E | 1 |
| Wyatt, CM | 1 |
| Nichols, BE | 1 |
| Boucher, CA | 1 |
| van Dijk, JH | 1 |
| Thuma, PE | 1 |
| Nouwen, JL | 1 |
| Baltussen, R | 1 |
| van de Wijgert, J | 1 |
| Sloot, PM | 1 |
| van de Vijver, DA | 1 |
| Valluru, RK | 1 |
| B, PB | 1 |
| S, KS | 1 |
| V, PK | 1 |
| Kilaru, NB | 1 |
| Hu, CW | 1 |
| Hsu, YW | 1 |
| Chen, JL | 1 |
| Tam, LM | 1 |
| Chao, MR | 1 |
| Jia, S | 1 |
| Wang, F | 1 |
| Li, F | 1 |
| Chang, K | 1 |
| Yang, S | 1 |
| Zhang, K | 1 |
| Jiang, W | 1 |
| Shang, Y | 1 |
| Deng, S | 1 |
| Chen, M | 1 |
| Cai, SH | 1 |
| Lv, FF | 1 |
| Zhang, YH | 1 |
| Jiang, YG | 1 |
| Peng, J | 1 |
| Boyd, A | 2 |
| Maylin, S | 2 |
| Gozlan, J | 1 |
| Delaugerre, C | 2 |
| Simon, F | 2 |
| Girard, PM | 2 |
| Lacombe, K | 2 |
| Wang, Y | 2 |
| Chen, H | 2 |
| Wu, Y | 1 |
| Ge, H | 1 |
| Ye, G | 1 |
| Hu, X | 1 |
| Yang, T | 1 |
| Yang, R | 1 |
| Nan, F | 1 |
| Ge, T | 1 |
| Jiao, K | 2 |
| Santangelo, PJ | 1 |
| Rogers, KA | 1 |
| Zurla, C | 1 |
| Blanchard, EL | 1 |
| Gumber, S | 1 |
| Strait, K | 1 |
| Connor-Stroud, F | 1 |
| Schuster, DM | 1 |
| Amancha, PK | 1 |
| Hong, JJ | 1 |
| Byrareddy, SN | 1 |
| Hoxie, JA | 1 |
| Vidakovic, B | 1 |
| Ansari, AA | 1 |
| Hunter, E | 1 |
| Villinger, F | 1 |
| Arvand, M | 1 |
| Ghodsi, N | 1 |
| Zanjanchi, MA | 1 |
| Lu, W | 1 |
| Zheng, Y | 1 |
| Wang, W | 1 |
| Bai, L | 1 |
| Chen, L | 2 |
| Feng, Y | 1 |
| Zhang, Z | 1 |
| Yuan, Z | 1 |
| Xiao, Q | 1 |
| Wang, D | 1 |
| Yang, W | 1 |
| Ding, Y | 1 |
| Yang, J | 1 |
| Albitar, A | 1 |
| DeDios, I | 1 |
| Estella, J | 1 |
| Ahn, I | 1 |
| Farooqui, M | 1 |
| Wiestner, A | 1 |
| Albitar, M | 1 |
| Chang, KW | 1 |
| Oh, J | 1 |
| Alvord, WG | 1 |
| Hughes, SH | 1 |
| Fatemi, K | 1 |
| Ghourchian, H | 1 |
| Ziaee, AA | 1 |
| Samiei, S | 1 |
| Hanaee, H | 1 |
| Ray, AS | 1 |
| Wright, MR | 1 |
| Rhodes, GR | 1 |
| Kamel, AH | 1 |
| Moreira, FT | 1 |
| Delerue-Matos, C | 1 |
| Sales, MG | 1 |
| D'Avolio, A | 1 |
| Sciandra, M | 1 |
| Siccardi, M | 1 |
| Baietto, L | 1 |
| Gonzalez de Requena, D | 1 |
| Bonora, S | 1 |
| Di Perri, G | 1 |
| Gomes, NA | 1 |
| Vaidya, VV | 1 |
| Pudage, A | 1 |
| Joshi, SS | 1 |
| Parekh, SA | 1 |
| Schackman, BR | 1 |
| Scott, CA | 1 |
| Walensky, RP | 1 |
| Losina, E | 1 |
| Freedberg, KA | 1 |
| Sax, PE | 1 |
| Sun, W | 1 |
| Li, Y | 1 |
| Duan, Y | 1 |
| Degertekin, B | 1 |
| Hussain, M | 2 |
| Tan, J | 1 |
| Oberhelman, K | 1 |
| Lok, AS | 2 |
| Lupo, J | 1 |
| Larrat, S | 1 |
| Hilleret, MN | 1 |
| Germi, R | 1 |
| Boyer, V | 1 |
| Nicod, S | 1 |
| Barguès, G | 1 |
| Leroy, V | 1 |
| Seigneurin, JM | 1 |
| Zarski, JP | 1 |
| Morand, P | 1 |
| Colborn, JM | 1 |
| Byrd, BD | 1 |
| Koita, OA | 1 |
| Krogstad, DJ | 1 |
| Jaafar, A | 1 |
| Séronie-Vivien, S | 1 |
| Malard, L | 1 |
| Massip, P | 1 |
| Chatelut, E | 1 |
| Tack, I | 1 |
| Sturm, MB | 1 |
| Schramm, VL | 1 |
| Aung, Z | 1 |
| Tong, JC | 1 |
| Delahunty, T | 3 |
| Bushman, L | 3 |
| Robbins, B | 1 |
| Fletcher, CV | 3 |
| Solínová, V | 1 |
| Kasicka, V | 1 |
| Sázelová, P | 1 |
| Holý, A | 1 |
| Hall, AM | 1 |
| Edwards, SG | 1 |
| Lapsley, M | 1 |
| Connolly, JO | 1 |
| Chetty, K | 1 |
| O'Farrell, S | 1 |
| Unwin, RJ | 1 |
| Williams, IG | 1 |
| Cho, H | 1 |
| Lee, B | 1 |
| Liu, GL | 1 |
| Agarwal, A | 1 |
| Lee, LP | 1 |
| Zhu, Z | 2 |
| Zhou, X | 1 |
| Yan, N | 1 |
| Zhou, L | 1 |
| Chen, X | 2 |
| Zhao, WF | 1 |
| Shao, YL | 1 |
| Chen, LY | 1 |
| Wu, JH | 1 |
| Zhu, YL | 1 |
| Gan, JH | 1 |
| Xiong, H | 1 |
| Pietrzyk, A | 1 |
| Suriyanarayanan, S | 1 |
| Kutner, W | 1 |
| Chitta, R | 1 |
| Zandler, ME | 1 |
| D'Souza, F | 1 |
| Jang, H | 1 |
| Kim, J | 1 |
| Choi, JJ | 1 |
| Son, Y | 1 |
| Park, H | 1 |
| Kouguchi, Y | 1 |
| Teramoto, M | 1 |
| Kuramoto, M | 1 |
| Cui, L | 1 |
| Zhong, Y | 1 |
| Zhu, W | 1 |
| Xu, Y | 1 |
| Qian, X | 1 |
| Yadav, M | 1 |
| Singhal, P | 1 |
| Goswami, S | 1 |
| Pande, UC | 1 |
| Sanyal, M | 1 |
| Shrivastav, PS | 1 |
| Krais, AM | 1 |
| Cornelius, MG | 1 |
| Schmeiser, HH | 1 |
| Wang, P | 1 |
| Wu, H | 1 |
| Dai, Z | 1 |
| Zou, X | 1 |
| Meesters, RJ | 1 |
| van Kampen, JJ | 1 |
| Scheuer, RD | 1 |
| van der Ende, ME | 1 |
| Gruters, RA | 1 |
| Luider, TM | 1 |
| Bushman, LR | 1 |
| Kiser, JJ | 1 |
| Rower, JE | 1 |
| Klein, B | 1 |
| Zheng, JH | 1 |
| Ray, ML | 1 |
| Anderson, PL | 2 |
| Shi, J | 1 |
| Liu, HF | 1 |
| Wong, JM | 1 |
| Huang, RN | 1 |
| Jones, E | 1 |
| Carlson, TJ | 1 |
| Matta, MK | 1 |
| Burugula, L | 1 |
| Pilli, NR | 1 |
| Inamadugu, JK | 1 |
| J V L N, SR | 1 |
| Havele, S | 1 |
| Dhaneshwar, SR | 1 |
| Chen, HJ | 3 |
| Liu, YF | 1 |
| Thappali, SR | 1 |
| Varanasi, KV | 1 |
| Veeraraghavan, S | 1 |
| Vakkalanka, SK | 1 |
| Mukkanti, K | 1 |
| Martinot-Peignoux, M | 1 |
| Bagnard, G | 1 |
| Lapalus, M | 1 |
| Zoulim, F | 1 |
| Lavocat, F | 1 |
| Marcellin, P | 1 |
| Fujita, Y | 1 |
| Mori, I | 1 |
| Yamaguchi, T | 1 |
| Nakajima, N | 2 |
| Ionescu, P | 1 |
| Sato, Y | 1 |
| Hashimoto, M | 1 |
| Kuroita, T | 1 |
| Takahashi, H | 1 |
| Yoshikura, H | 2 |
| Sata, T | 1 |
| Lauer, T | 1 |
| Loncar, R | 1 |
| Deussen, A | 1 |
| Wu, K | 1 |
| Fei, J | 1 |
| Bai, W | 1 |
| Hu, S | 1 |
| Crommentuyn, KM | 1 |
| Schellens, JH | 1 |
| Blagoeva, E | 1 |
| Malbeck, J | 1 |
| Gaudinová, A | 1 |
| Vanek, T | 1 |
| Vanková, R | 1 |
| Sentenac, S | 1 |
| Fernandez, C | 1 |
| Thuillier, A | 1 |
| Lechat, P | 1 |
| Aymard, G | 1 |
| Xu, G | 1 |
| Xu, C | 1 |
| Garcia, L | 1 |
| Lin, CC | 1 |
| Yeh, LT | 1 |
| Rappaport, HP | 1 |
| Caruso, R | 1 |
| Campolo, J | 1 |
| Dellanoce, C | 1 |
| Mariele, R | 1 |
| Parodi, O | 1 |
| Accinni, R | 1 |
| Hines, HB | 1 |
| Brueggemann, EE | 1 |
| Hale, ML | 1 |
| Chang, CM | 1 |
| Koo, TW | 1 |
| Chan, S | 1 |
| Sun, L | 1 |
| Su, X | 1 |
| Zhang, J | 1 |
| Berlin, AA | 1 |
| Serganov, A | 1 |
| Yuan, YR | 1 |
| Pikovskaya, O | 1 |
| Polonskaia, A | 1 |
| Malinina, L | 1 |
| Phan, AT | 1 |
| Hobartner, C | 1 |
| Micura, R | 1 |
| Breaker, RR | 1 |
| Patel, DJ | 1 |
| Kawata, S | 1 |
| Inouye, Y | 1 |
| Ichimura, T | 1 |
| Thompson, M | 1 |
| Desbat, B | 1 |
| Manet, S | 1 |
| Aimé, C | 1 |
| Labrot, T | 1 |
| Oda, R | 1 |
| Jaroniec, CP | 1 |
| Boisbouvier, J | 1 |
| Tworowska, I | 1 |
| Nikonowicz, EP | 1 |
| Bax, A | 1 |
| Sarai, A | 1 |
| Kono, H | 1 |
| Kanwal, F | 1 |
| Gralnek, IM | 1 |
| Martin, P | 1 |
| Dulai, GS | 1 |
| Farid, M | 1 |
| Spiegel, BM | 1 |
| Zhang, D | 1 |
| Xie, Y | 1 |
| Deb, SK | 1 |
| Davison, VJ | 1 |
| Ben-Amotz, D | 1 |
| Rezk, NL | 1 |
| Crutchley, RD | 1 |
| Kashuba, AD | 1 |
| Bruchmüller, I | 1 |
| Janetzko, K | 1 |
| Bugert, P | 1 |
| Mayaudon, V | 1 |
| Corash, L | 1 |
| Lin, L | 1 |
| Klüter, H | 1 |
| Bi, HC | 1 |
| Zhong, GP | 1 |
| Zhou, S | 1 |
| Huang, M | 1 |
| Rozenberg, M | 1 |
| Shoham, G | 1 |
| Reva, I | 1 |
| Fausto, R | 1 |
| Badouard, C | 1 |
| Masuda, M | 1 |
| Nishino, H | 1 |
| Cadet, J | 2 |
| Favier, A | 1 |
| Ravanat, JL | 1 |
| Fung, S | 1 |
| Libbrecht, E | 1 |
| Sablon, E | 1 |
| Cursaro, C | 1 |
| Andreone, P | 1 |
| Hiki, S | 1 |
| Mawatari, K | 1 |
| Hibara, A | 1 |
| Tokeshi, M | 1 |
| Kitamori, T | 1 |
| Zhao, Y | 1 |
| Ye, T | 1 |
| Liu, H | 1 |
| Kou, Y | 1 |
| Li, M | 2 |
| Shao, Y | 1 |
| Zhuang, Q | 1 |
| Osiowy, C | 1 |
| Villeneuve, JP | 1 |
| Heathcote, EJ | 1 |
| Giles, E | 1 |
| Borlang, J | 1 |
| Sun, D | 1 |
| Wang, H | 1 |
| Wang, B | 1 |
| Guo, R | 1 |
| Fraser, ME | 1 |
| Cherney, MM | 1 |
| Marcato, P | 1 |
| Mulvey, GL | 1 |
| Armstrong, GD | 1 |
| James, MN | 1 |
| King, T | 1 |
| Kiser, J | 1 |
| Ray, M | 1 |
| Johnson, JA | 1 |
| Rompay, KK | 1 |
| Delwart, E | 1 |
| Heneine, W | 1 |
| Dal Pozzo, F | 1 |
| Andrei, G | 1 |
| Lebeau, I | 1 |
| Beadle, JR | 2 |
| Hostetler, KY | 2 |
| De Clercq, E | 2 |
| Snoeck, R | 1 |
| Becher, F | 1 |
| Duriez, E | 1 |
| Volland, H | 1 |
| Tabet, JC | 1 |
| Ezan, E | 1 |
| Allice, T | 1 |
| Cerutti, F | 1 |
| Pittaluga, F | 1 |
| Varetto, S | 1 |
| Gabella, S | 1 |
| Marzano, A | 1 |
| Franchello, A | 1 |
| Colucci, G | 1 |
| Ghisetti, V | 1 |
| Izzo, JG | 1 |
| Wu, TT | 1 |
| Wu, X | 1 |
| Ensor, J | 1 |
| Luthra, R | 1 |
| Pan, J | 1 |
| Correa, A | 1 |
| Swisher, SG | 1 |
| Chao, CK | 1 |
| Hittelman, WN | 1 |
| Ajani, JA | 1 |
| Ruiz, JC | 1 |
| Aldern, KA | 1 |
| Keith, KA | 1 |
| Hartline, CB | 1 |
| Kern, ER | 1 |
| El Barkil, M | 1 |
| Gagnieu, MC | 1 |
| Guitton, J | 1 |
| Bennetto-Hood, C | 1 |
| Long, MC | 1 |
| Acosta, EP | 1 |
| Wood, NJ | 1 |
| Brannigan, JA | 1 |
| Duckett, SB | 1 |
| Heath, SL | 1 |
| Wagstaff, J | 1 |
| Liu, FH | 1 |
| Jiang, Y | 1 |
| He, P | 1 |
| Shen, L | 1 |
| Cao, Y | 1 |
| Li, D | 1 |
| Sablon, N | 1 |
| De Proft, F | 1 |
| Geerlings, P | 1 |
| Tozer, DJ | 1 |
| Dogan, B | 1 |
| Uslu, B | 1 |
| Ozkan, SA | 1 |
| Zuman, P | 1 |
| Sapio, MR | 1 |
| Guerra, A | 1 |
| Posca, D | 1 |
| Limone, PP | 1 |
| Deandrea, M | 1 |
| Motta, M | 1 |
| Troncone, G | 1 |
| Caleo, A | 1 |
| Vallefuoco, P | 1 |
| Rossi, G | 1 |
| Fenzi, G | 1 |
| Vitale, M | 1 |
| Chadt, J | 1 |
| Sykora, D | 1 |
| Nilsson, R | 1 |
| Vodicka, P | 2 |
| Choudhury, S | 1 |
| Adhikari, S | 1 |
| Cheema, A | 1 |
| Roy, R | 1 |
| Vinogradov, AE | 1 |
| Rosanov, JM | 1 |
| Neagu, I | 1 |
| Koivisto, P | 1 |
| Neagu, C | 1 |
| Kaltia, S | 1 |
| Kostiainen, R | 1 |
| Peltonen, K | 1 |
| Fennell, TR | 1 |
| Prosnyak, MI | 1 |
| Veselovskaya, SI | 1 |
| Myasnikov, VA | 1 |
| Efremova, EJ | 1 |
| Potapov, VK | 1 |
| Limborska, SA | 1 |
| Sverdlov, ED | 1 |
| Batova, IN | 1 |
| Kyurkchiev, SD | 1 |
| Kehayov, IR | 1 |
| Strick, R | 1 |
| Laemmli, UK | 1 |
| Lazarowski, ER | 1 |
| Watt, WC | 1 |
| Stutts, MJ | 1 |
| Boucher, RC | 1 |
| Harden, TK | 1 |
| Douki, T | 1 |
| Delatour, T | 1 |
| Bianchini, F | 1 |
| Michie, AM | 1 |
| Lobban, M | 1 |
| Müller, T | 1 |
| Harnett, MM | 1 |
| Houslay, MD | 1 |
| Curto, R | 1 |
| Voit, EO | 1 |
| Sorribas, A | 1 |
| Cascante, M | 1 |
| Weng, YS | 1 |
| Nickoloff, JA | 1 |
| Xu, L | 1 |
| Rahimpour, R | 1 |
| Ran, L | 1 |
| Kong, C | 1 |
| Biragyn, A | 1 |
| Andrews, J | 1 |
| Devries, M | 1 |
| Wang, JM | 1 |
| Kelvin, DJ | 1 |
| Sue, M | 1 |
| Miyoshi, H | 1 |
| Iwamura, H | 1 |
| Hanaki, K | 1 |
| Shimizu, YK | 1 |
| Ohnishi, S | 1 |
| Gunji, T | 1 |
| Nakajima, A | 1 |
| Nozaki, C | 1 |
| Mizuno, K | 1 |
| Odawara, T | 1 |
| Brigotti, M | 1 |
| Barbieri, L | 1 |
| Valbonesi, P | 1 |
| Stirpe, F | 1 |
| Montanaro, L | 1 |
| Sperti, S | 1 |
| Kawamoto, Y | 1 |
| Shinozuka, K | 1 |
| Kunitomo, M | 1 |
| Haginaka, J | 1 |
| Urata, M | 1 |
| Wakiyama, M | 1 |
| Iwase, M | 1 |
| Yoneda, M | 1 |
| Kinoshita, S | 1 |
| Hamasaki, N | 1 |
| Kang, D | 1 |
| Hatse, S | 1 |
| Balzarini, J | 1 |
| Bolante-Cervantes, R | 1 |
| Li, S | 1 |
| Sahota, A | 1 |
| Tischfield, JA | 1 |
| Zwerdling, T | 1 |
| Stambrook, PJ | 1 |
| Chiang, LC | 1 |
| Tseng, MC | 1 |
| Zhang, LL | 1 |
| Ni, J | 1 |
| Chung, FL | 1 |
| Braybrooke, JP | 1 |
| Houlbrook, S | 1 |
| Crawley, JE | 1 |
| Propper, DJ | 1 |
| O'Byrne, KJ | 1 |
| Stratford, IJ | 1 |
| Harris, AL | 1 |
| Shuker, DE | 1 |
| Talbot, DC | 1 |
| Veldkamp, A | 1 |
| Hoetelmans, RM | 1 |
| Sabourin, M | 1 |
| Osheroff, N | 1 |
| Wessel, T | 1 |
| Lanvers, C | 1 |
| Fruend, S | 1 |
| Hempel, G | 1 |
| Yang, HH | 1 |
| Zhu, QZ | 1 |
| Chen, QY | 1 |
| Li, DH | 1 |
| Xu, JG | 1 |
| Koskinen, M | 1 |
| Hemminki, K | 1 |
| Trnková, L | 1 |
| Friml, J | 1 |
| Dracka, O | 1 |
| Heisler, I | 1 |
| Keller, J | 1 |
| Tauber, R | 1 |
| Sutherland, M | 1 |
| Fuchs, H | 1 |
| Wang, J | 1 |
| Shi, Z | 1 |
| Li, N | 1 |
| Gu, Z | 1 |
| Khabar, KS | 1 |
| Dhalla, M | 1 |
| Bakheet, T | 1 |
| Sy, C | 1 |
| al-Haj, L | 1 |
| Parsons, BL | 1 |
| Culp, SJ | 1 |
| Manjanatha, MG | 1 |
| Heflich, RH | 1 |
| Kar, L | 1 |
| De Croos, PZ | 1 |
| Roman, SJ | 1 |
| Matsumura, P | 1 |
| Johnson, ME | 1 |
| Leedman, PJ | 1 |
| Frauman, AG | 1 |
| Colman, PG | 1 |
| Michelangeli, VP | 1 |
| Fujise, H | 1 |
| Higashijima, M | 1 |
| Sakamoto, Y | 1 |
| Sonoki, S | 1 |
| Hisamatsu, S | 1 |
| Ogawa, E | 1 |
| Takahashi, R | 1 |
| Linden, J | 1 |
| Taylor, HE | 1 |
| Feldman, MD | 1 |
| Woodward, EB | 1 |
| Ayers, CR | 1 |
| Ripley, ML | 1 |
| Iflah, S | 1 |
| Patel, A | 1 |
| Gregersen, N | 1 |
| Blakemore, AI | 1 |
| Winter, V | 1 |
| Andresen, B | 1 |
| Kølvraa, S | 1 |
| Bolund, L | 1 |
| Curtis, D | 1 |
| Engel, PC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study Using 123I Radiolabeled 3BNC117 SPECT/CT to Image HIV Reservoir in Chronically Infected HIV Patients[NCT03468582] | Early Phase 1 | 6 participants (Actual) | Interventional | 2018-02-08 | Completed | ||
| Effects of Sofosbuvir/Ledipasvir Treatment on the Pharmacokinetics and Renal Safety of Tenofovir[NCT02588287] | 14 participants (Actual) | Interventional | 2015-11-30 | Completed | |||
| Severe Impairment of Solute-Free Water Clearance in Patients With HIV Infection[NCT01869010] | 30 participants (Actual) | Observational | 2010-01-31 | Completed | |||
| Effects of Ledipasvir/Sofosbuvir Treatment on the Pharmacokinetics and Renal Safety of Tenofovir Alafenamide (TAF) in Patients With HIV.[NCT03126370] | Phase 4 | 10 participants (Actual) | Interventional | 2018-01-08 | Completed | ||
| CID 0708 - Sex, Aging and Antiretroviral Pharmacokinetics[NCT00666055] | 11 participants (Actual) | Observational | 2008-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Compare plasma tenofovir AUC0-24 between TAF with boosted PI vs. TDF with boosted PI (Phase 2 vs. 1), and between TAF with boosted PI and LDV/SOF vs. TDF with boosted PI (Phase 3 vs. 1) (NCT03126370)
Timeframe: 12 weeks and 24 weeks and 28 weeks
| Intervention | ng*h/mL (Geometric Mean) |
|---|---|
| TDF With a Boosted PI | 3466 |
| TAF With a Boosted PI | 743 |
| TAF With a Boosted PI and LDV/SOF | 868 |
Compare tenofovir diphosphate (TFV-DP) in dried blood spots (DBS) between TAF with a boosted PI vs. TDF with a boosted PI (Phase 2 vs. 1), and TAF with a boosted PI and LDV/SOF vs. TDF with a boosted PI (Phase 3 vs. 1) (NCT03126370)
Timeframe: 12 weeks and 24 and 28 weeks
| Intervention | fmol/2x7mm punches (Geometric Mean) |
|---|---|
| TDF With a Boosted PI | 36014 |
| TAF With a Boosted PI | 6735 |
| TAF With a Boosted PI and LDV/SOF | 6100 |
Compare tenofovir-diphosphate (TFV-DP) in peripheral blood mononuclear cells (PBMCs) between TAF with a boosted PI vs. TDF with a boosted PI (Phase 2 vs. 1), and TAF with a boosted PI and LDV/SOF vs. TDF with a boosted PI (Phase 3 vs. 1). (NCT03126370)
Timeframe: 12 weeks, and 24 weeks and 28 weeks
| Intervention | fmol/10^6 cells (Geometric Mean) |
|---|---|
| TDF With a Boosted PI | 83.0 |
| TAF With a Boosted PI | 926 |
| TAF With a Boosted PI and LDV/SOF | 1129 |
Change in estimated glomerular filtration rate (eGFR) (NCT03126370)
Timeframe: 12 weeks, 24 weeks, and 28 weeks
| Intervention | mL/min/1.73 m^2 (Geometric Mean) |
|---|---|
| TDF With a Boosted PI | 86.7 |
| TAF With a Boosted PI | 91.0 |
| TAF With a Boosted PI and LDV/SOF | 88.1 |
Change in estimated glomerular filtration rate (eGFR) and renal biomarkers: Urine protein to creatinine ratio (UPCR) (NCT03126370)
Timeframe: 12 weeks, 24 weeks, and 28 weeks
| Intervention | mg/g (Geometric Mean) |
|---|---|
| TDF With a Boosted PI | 134 |
| TAF With a Boosted PI | 118 |
| TAF With a Boosted PI and LDV/SOF | 97.3 |
Change in renal biomarkers: urinary beta-2 microglobulin (B2M)/creatinine (Cr) ratio, and urinary retinol binding protein (RBP)/Cr ratio (NCT03126370)
Timeframe: 12 weeks, 24 weeks, and 28 weeks
| Intervention | ug/g (Geometric Mean) | |
|---|---|---|
| β2M:Cr ratio | RBP:Cr ratio | |
| TAF With a Boosted PI | 224 | 242 |
| TAF With a Boosted PI and LDV/SOF | 178 | 146 |
| TDF With a Boosted PI | 419 | 436 |
2 reviews available for adenine and Sensitivity and Specificity
| Article | Year |
|---|---|
Near-field optics and spectroscopy for molecular nano-imaging.
Topics: Adenine; DNA; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Models, Biological; Nanotech | 2004 |
Protein-DNA recognition patterns and predictions.
Topics: Adenine; Biophysics; DNA; DNA-Binding Proteins; Genome, Fungal; Genomics; Models, Molecular; Nucleic | 2005 |
3 trials available for adenine and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous determination of pradefovir, PMEA and tenofovir in HBV patient serum using liquid chromatography-tandem mass spectrometry and application to phase 2 clinical trial.
Topics: Adenine; Adult; Chromatography, High Pressure Liquid; Drug Stability; Female; Humans; Linear Models; | 2016 |
Selective determination of antiretroviral agents tenofovir, emtricitabine, and lamivudine in human plasma by a LC-MS-MS method for a bioequivalence study in healthy Indian subjects.
Topics: Adenine; Adult; Anti-Retroviral Agents; Chromatography, Liquid; Cross-Over Studies; Deoxycytidine; D | 2010 |
New sensitive method for the detection of the A3243G mutation of human mitochondrial deoxyribonucleic acid in diabetes mellitus patients by ligation-mediated polymerase chain reaction.
Topics: Adenine; Adult; Aged; Aged, 80 and over; Cell Line; Diabetes Mellitus; DNA, Mitochondrial; Female; G | 1998 |
141 other studies available for adenine and Sensitivity and Specificity
| Article | Year |
|---|---|
Characterizing the Impact of Primer-Template Mismatches on Recombinase Polymerase Amplification.
Topics: Adenine; Cytosine; DNA Primers; Humans; Nucleic Acid Amplification Techniques; Nucleic Acids; Recomb | 2022 |
Development and validation of a rapid LC-MS/MS method for determination of methylated nucleosides and nucleobases in urine.
Topics: Adenine; Adult; Animals; Child; Chromatography, Liquid; Guanine; Humans; Linear Models; Nucleosides; | 2019 |
Simulated NIR spectra as sensitive markers of the structure and interactions in nucleobases.
Topics: Adenine; Binding Sites; Biophysical Phenomena; Computer Simulation; Crystallization; Cytosine; Guani | 2019 |
Multiplexed Functional Assessment of Genetic Variants in CARD11.
Topics: Adenine; B-Cell CLL-Lymphoma 10 Protein; B-Lymphocytes; CARD Signaling Adaptor Proteins; Cell Line; | 2020 |
Bioanalysis of ibrutinib, and its dihydrodiol- and glutathione cycle metabolites by liquid chromatography-tandem mass spectrometry.
Topics: Adenine; Aged; Chromatography, Liquid; Drug Stability; Glutathione; Humans; Linear Models; Male; Nap | 2018 |
Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing.
Topics: Adenine; Animals; Animals, Newborn; Cell Line, Tumor; Disease Models, Animal; Female; Genome, Human; | 2018 |
Targeting fidelity of adenine and cytosine base editors in mouse embryos.
Topics: Adenine; Alleles; Animals; Animals, Genetically Modified; CRISPR-Associated Protein 9; CRISPR-Cas Sy | 2018 |
Genome-wide profiling of adenine base editor specificity by EndoV-seq.
Topics: Adenine; Animals; Bacterial Proteins; Base Sequence; CRISPR-Associated Proteins; Deamination; Deoxyr | 2019 |
Development and validation of an assay for the simultaneous determination of zidovudine, abacavir, emtricitabine, lamivudine, tenofovir and ribavirin in human plasma using liquid chromatography-tandem mass spectrometry.
Topics: Adenine; Antiviral Agents; Chromatography, Liquid; Deoxyribonucleosides; Drug Stability; Humans; Lin | 2013 |
Urinary beta-2 microglobulin and alpha-1 microglobulin are useful screening markers for tenofovir-induced kidney tubulopathy in patients with HIV-1 infection: a diagnostic accuracy study.
Topics: Adenine; Adult; Alpha-Globulins; Anti-Retroviral Agents; beta 2-Microglobulin; Biomarkers; Chi-Squar | 2013 |
Urine processing impacts uric acid level in HIV-infected adults: implications for diagnosing tenofovir-associated proximal tubulopathy.
Topics: Adenine; Adult; AIDS-Associated Nephropathy; Anti-HIV Agents; HIV Infections; Humans; Organophosphon | 2013 |
Cost-effectiveness of pre-exposure prophylaxis (PrEP) in preventing HIV-1 infections in rural Zambia: a modeling study.
Topics: Adenine; Anti-HIV Agents; Cost-Benefit Analysis; Deoxycytidine; Emtricitabine; HIV Infections; HIV-1 | 2013 |
High throughput LC-MS/MS method for simultaneous determination of tenofovir, lamivudine and nevirapine in human plasma.
Topics: Adenine; Chromatography, High Pressure Liquid; Humans; Lamivudine; Linear Models; Male; Nevirapine; | 2013 |
Direct analysis of tobacco-specific nitrosamine NNK and its metabolite NNAL in human urine by LC-MS/MS: evidence of linkage to methylated DNA lesions.
Topics: Adenine; Adult; Biomarkers; Chromatography, Liquid; Cotinine; DNA Methylation; Guanine; Humans; Limi | 2014 |
Rapid detection of hepatitis B virus variants associated with lamivudine and adefovir resistance by multiplex ligation-dependent probe amplification combined with real-time PCR.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; | 2014 |
Dynamic comparison between Daan real-time PCR and Cobas TaqMan for quantification of HBV DNA levels in patients with CHB.
Topics: Adenine; Adolescent; Adult; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B virus; Hepati | 2014 |
Use of hepatitis B surface and "e" antigen quantification during extensive treatment with tenofovir in patients co-infected with HIV-HBV.
Topics: Adenine; Adult; Anti-HIV Agents; Coinfection; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis | 2015 |
Metal-organic frameworks and β-cyclodextrin-based composite electrode for simultaneous quantification of guanine and adenine in a lab-on-valve manifold.
Topics: Adenine; Animals; Beer; beta-Cyclodextrins; Blood; Cattle; Electrochemical Techniques; Electrodes; F | 2014 |
Electrocatalytic activity of molybdenum disulfide nanosheets enhanced by self-doped polyaniline for highly sensitive and synergistic determination of adenine and guanine.
Topics: Adenine; Aniline Compounds; Catalysis; Disulfides; Electrochemical Techniques; Guanine; Molybdenum; | 2015 |
Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy-treated macaques.
Topics: Adenine; Animals; Anti-Retroviral Agents; Copper Radioisotopes; Deoxycytidine; Emtricitabine; Immuno | 2015 |
A new microplatform based on titanium dioxide nanofibers/graphene oxide nanosheets nanocomposite modified screen printed carbon electrode for electrochemical determination of adenine in the presence of guanine.
Topics: Adenine; Carbon; Complex Mixtures; Conductometry; Equipment Design; Equipment Failure Analysis; Grap | 2016 |
In situ analysis of intrahepatic virological events in chronic hepatitis B virus infection.
Topics: Adenine; Case-Control Studies; DNA Probes; DNA, Viral; Hep G2 Cells; Hepatitis B Core Antigens; Hepa | 2016 |
Using high-sensitivity sequencing for the detection of mutations in BTK and PLCγ2 genes in cellular and cell-free DNA and correlation with progression in patients treated with BTK inhibitors.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Agents; DNA; Drug Resistance, Neoplasm; | 2017 |
The effects of alternate polypurine tracts (PPTs) and mutations of sequences adjacent to the PPT on viral replication and cleavage specificity of the Rous sarcoma virus reverse transcriptase.
Topics: Adenine; Animals; Base Sequence; Cell Line; Cells, Cultured; Chick Embryo; Consensus Sequence; Embry | 2008 |
Paramagnetic nanoparticle-based detection of hepatitis B virus using cathodic stripping voltammetry.
Topics: Adenine; DNA Primers; DNA, Viral; Electrochemical Techniques; Hepatitis B virus; Humans; Magnetics; | 2009 |
Lack of evidence for an effect of lopinavir/ritonavir on tenofovir renal clearance.
Topics: Adenine; Creatinine; Drug Interactions; Drug Therapy, Combination; Female; Glomerular Filtration Rat | 2008 |
Electrochemical determination of antioxidant capacities in flavored waters by guanine and adenine biosensors.
Topics: Adenine; Antioxidants; Beverages; Biosensing Techniques; Electrochemistry; Equipment Design; Equipme | 2008 |
A new assay based on solid-phase extraction procedure with LC-MS to measure plasmatic concentrations of tenofovir and emtricitabine in HIV infected patients.
Topics: Adenine; Anti-HIV Agents; Calibration; Chromatography, Liquid; Deoxycytidine; Emtricitabine; HIV Inf | 2008 |
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for simultaneous determination of tenofovir and emtricitabine in human plasma and its application to a bioequivalence study.
Topics: Adenine; Calibration; Chromatography, Liquid; Deoxycytidine; Drug Combinations; Drug Stability; Emtr | 2008 |
The cost-effectiveness of HLA-B*5701 genetic screening to guide initial antiretroviral therapy for HIV.
Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cost-Benefit Analysis; Dideo | 2008 |
Direct electrocatalytic oxidation of adenine and guanine on carbon ionic liquid electrode and the simultaneous determination.
Topics: Adenine; Biosensing Techniques; Catalysis; Complex Mixtures; Electrochemistry; Electrodes; Equipment | 2008 |
Sensitivity and accuracy of an updated line probe assay (HBV DR v.3) in detecting mutations associated with hepatitis B antiviral resistance.
Topics: Adenine; Adult; Antiviral Agents; DNA Probes; DNA, Viral; Drug Resistance, Viral; Female; Guanine; H | 2009 |
Assessment of selective real-time PCR for quantitation of lamivudine and adefovir hepatitis B virus-resistant strains and comparison with direct sequencing and line probe assays.
Topics: Adenine; Antiviral Agents; DNA Mutational Analysis; DNA, Viral; Drug Resistance, Viral; Genotype; He | 2009 |
Estimation of copy number using SYBR Green: confounding by AT-rich DNA and by variation in amplicon length.
Topics: Adenine; Animals; Anopheles; Base Sequence; Benzothiazoles; Diamines; DNA; DNA, Protozoan; Female; F | 2008 |
Urinary cystatin C can improve the renal safety follow-up of tenofovir-treated patients.
Topics: Adenine; Anti-HIV Agents; Biomarkers; Creatinine; Cystatin C; Fanconi Syndrome; HIV Infections; Huma | 2009 |
Detecting ricin: sensitive luminescent assay for ricin A-chain ribosome depurination kinetics.
Topics: Adenine; Adenosine Monophosphate; Animals; Inverted Repeat Sequences; Kinetics; Luciferases, Firefly | 2009 |
BSAlign: a rapid graph-based algorithm for detecting ligand-binding sites in protein structures.
Topics: Adenine; Algorithms; Binding Sites; Computational Biology; Computer Graphics; Enzymes; Ligands; Mode | 2008 |
The simultaneous assay of tenofovir and emtricitabine in plasma using LC/MS/MS and isotopically labeled internal standards.
Topics: Adenine; Anti-HIV Agents; Chromatography, High Pressure Liquid; Deoxycytidine; Drug Stability; Emtri | 2009 |
Chiral analysis of anti-acquired immunodeficiency syndrome drug, 9-(R)-[2-(phosphonomethoxy)propyl]adenine (tenofovir), and related antiviral acyclic nucleoside phosphonates by CE using beta-CD as chiral selector.
Topics: Adenine; Anti-HIV Agents; beta-Cyclodextrins; Cidofovir; Cytosine; Electrolytes; Electrophoresis, Ca | 2009 |
Subclinical tubular injury in HIV-infected individuals on antiretroviral therapy: a cross-sectional analysis.
Topics: Acetylglucosaminidase; Adenine; Adult; Aged; Albuminuria; Anti-Retroviral Agents; Creatinine; Cross- | 2009 |
Label-free and highly sensitive biomolecular detection using SERS and electrokinetic preconcentration.
Topics: Adenine; Electrophoresis; Sensitivity and Specificity; Spectrum Analysis, Raman; Surface Properties | 2009 |
On-line combination of single-drop liquid-liquid-liquid microextraction with capillary electrophoresis for sample cleanup and preconcentration: a simple and efficient approach to determining trace analyte in real matrices.
Topics: Acetates; Adenine; Chemical Fractionation; Electrophoresis, Capillary; Hydrochloric Acid; Hydrogen-I | 2010 |
Establishment of a new quantitative detection approach to adefovir-resistant HBV and its clinical application.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Hepatitis B virus; Hep | 2010 |
Molecularly imprinted polymer (MIP) based piezoelectric microgravimetry chemosensor for selective determination of adenine.
Topics: Acoustics; Adenine; Equipment Design; Equipment Failure Analysis; Micro-Electrical-Mechanical System | 2010 |
Peptide nucleic acid array for detection of point mutations in hepatitis B virus associated with antiviral resistance.
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B vir | 2010 |
Real-time nucleic acid sequence-based amplification (NASBA) using an adenine-induced quenching probe and an intercalator dye.
Topics: Adenine; DNA, Bacterial; Intercalating Agents; RNA, Bacterial; Self-Sustained Sequence Replication; | 2010 |
Selective and sensitive detection and quantification of arylamine N-acetyltransferase 2 by a ratiometric fluorescence probe.
Topics: Acetylation; Adenine; Arylamine N-Acetyltransferase; Fluorescent Dyes; Hep G2 Cells; Humans; Microsc | 2010 |
Genomic N(6)-methyladenine determination by MEKC with LIF.
Topics: Adenine; Animals; Boron Compounds; Cattle; Chromatography, Micellar Electrokinetic Capillary; DNA; D | 2010 |
Simultaneous detection of guanine, adenine, thymine and cytosine at choline monolayer supported multiwalled carbon nanotubes film.
Topics: Adenine; Animals; Choline; Cytosine; DNA; Electrochemical Techniques; Fishes; Guanine; Nanotubes, Ca | 2011 |
Determination of the antiretroviral drug tenofovir in plasma from HIV-infected adults by ultrafast isotope dilution MALDI-triple quadrupole tandem mass spectrometry.
Topics: Adenine; Adult; Anti-HIV Agents; HIV Infections; Humans; Isotope Labeling; Linear Models; Organophos | 2011 |
Determination of nucleoside analog mono-, di-, and tri-phosphates in cellular matrix by solid phase extraction and ultra-sensitive LC-MS/MS detection.
Topics: Adenine; Anion Exchange Resins; Antiviral Agents; Calibration; Chromatography, Liquid; Deoxycytidine | 2011 |
Determination of nucleoside analog mono-, di-, and tri-phosphates in cellular matrix by solid phase extraction and ultra-sensitive LC-MS/MS detection.
Topics: Adenine; Anion Exchange Resins; Antiviral Agents; Calibration; Chromatography, Liquid; Deoxycytidine | 2011 |
Determination of nucleoside analog mono-, di-, and tri-phosphates in cellular matrix by solid phase extraction and ultra-sensitive LC-MS/MS detection.
Topics: Adenine; Anion Exchange Resins; Antiviral Agents; Calibration; Chromatography, Liquid; Deoxycytidine | 2011 |
Determination of nucleoside analog mono-, di-, and tri-phosphates in cellular matrix by solid phase extraction and ultra-sensitive LC-MS/MS detection.
Topics: Adenine; Anion Exchange Resins; Antiviral Agents; Calibration; Chromatography, Liquid; Deoxycytidine | 2011 |
Development of a robust and sensitive LC-MS/MS method for the determination of adenine in plasma of different species and its application to in vivo studies.
Topics: Adenine; Animals; Cats; Chromatography, Liquid; Haplorhini; Humans; Linear Models; Mice; Rats; Repro | 2011 |
A novel LC-MS/MS method for simultaneous quantification of tenofovir and lamivudine in human plasma and its application to a pharmacokinetic study.
Topics: Adenine; Chromatography, High Pressure Liquid; Drug Stability; Humans; Lamivudine; Linear Models; Ma | 2012 |
Stress studies of tenofovir disoproxil fumarate by HPTLC in bulk drug and pharmaceutical formulation.
Topics: Adenine; Chloroform; Chromatography, High Pressure Liquid; Drug Stability; Hydrolysis; Methanol; Org | 2012 |
Simultaneous quantitative analysis of N3-ethyladenine and N7-ethylguanine in human leukocyte deoxyribonucleic acid by stable isotope dilution capillary liquid chromatography-nanospray ionization tandem mass spectrometry.
Topics: Adenine; Adolescent; Adult; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Female; Guanine; | 2013 |
Simultaneous quantitation of IC87114, roflumilast and its active metabolite roflumilast N-oxide in plasma by LC-MS/MS: application for a pharmacokinetic study.
Topics: Adenine; Aminopyridines; Animals; Benzamides; Chromatography, High Pressure Liquid; Cyclopropanes; D | 2012 |
Quantification of hepatitis B e antigen between Elecsys HBeAg and Architect HBeAg assays among patients infected with hepatitis B virus.
Topics: Adenine; Adult; CD4 Lymphocyte Count; Cohort Studies; Coinfection; Female; Genotype; Hepatitis B e A | 2013 |
Spectrophotometric determination of biologically active thiols with eosin, silver(I) and adenine.
Topics: Adenine; Calibration; Coloring Agents; Disulfides; Eosine Yellowish-(YS); Injections; Ligands; Ophth | 2002 |
In situ hybridization AT-tailing with catalyzed signal amplification for sensitive and specific in situ detection of human immunodeficiency virus-1 mRNA in formalin-fixed and paraffin-embedded tissues.
Topics: Adenine; Adult; Antigens, Viral; Base Sequence; Child; Child, Preschool; DNA Probes; Female; HIV-1; | 2003 |
Tracer adenosine: a novel myocardial flow marker.
Topics: Adenine; Adenosine; Alprostadil; Animals; Carbon Radioisotopes; Coronary Circulation; Dogs; Isotope | 2003 |
Direct electrochemistry of DNA, guanine and adenine at a nanostructured film-modified electrode.
Topics: Adenine; Adsorption; Animals; Cattle; DNA; Electrochemistry; Electrodes; Guanine; Hydrogen-Ion Conce | 2003 |
Liquid chromatographic assay for the antiviral nucleotide analogue tenofovir in plasma using derivatization with chloroacetaldehyde.
Topics: Acetaldehyde; Adenine; Chromatography, Liquid; HIV Infections; Humans; Organophosphonates; Organopho | 2003 |
Cyclin-dependent kinase inhibitor, roscovitine, in combination with exogenous cytokinin, N6-benzyladenine, causes increase of cis-cytokinins in immobilized tobacco cells.
Topics: Adenine; Alginates; Benzyl Compounds; Cell Survival; Cells, Cultured; Cells, Immobilized; Cyclin-Dep | 2003 |
Sensitive determination of tenofovir in human plasma samples using reversed-phase liquid chromatography.
Topics: Adenine; Chromatography, High Pressure Liquid; Drug Monitoring; HIV Infections; Humans; Organophosph | 2003 |
Ultra sensitive method for the determination of 9-(2-phosphonylmethoxyethyl)adenine in human serum by liquid chromatography-tandem mass spectrometry.
Topics: Adenine; Antiviral Agents; Chromatography, Liquid; Humans; Mass Spectrometry; Organophosphonates; Re | 2004 |
The fidelity of replication of the three-base-pair set adenine/thymine, hypoxanthine/cytosine and 6-thiopurine/5-methyl-2-pyrimidinone with T7 DNA polymerase.
Topics: Adenine; Base Pairing; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Hypoxanthine; Kinetic | 2004 |
Critical study of preanalytical and analytical phases of adenine and pyridine nucleotide assay in human whole blood.
Topics: Adenine; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Humans; Nucleotides; Oxidati | 2004 |
High-performance liquid chromatography-mass selective detection assay for adenine released from a synthetic RNA substrate by ricin A chain.
Topics: Adenine; Chromatography, High Pressure Liquid; Mass Spectrometry; Reproducibility of Results; Ricin; | 2004 |
Quantification of urinary excretion of 1,N6-ethenoadenine, a potential biomarker of lipid peroxidation, in humans by stable isotope dilution liquid chromatography-electrospray ionization-tandem mass spectrometry: comparison with gas chromatography-mass sp
Topics: Adenine; Biomarkers; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Hum | 2004 |
Specific chemical effects on surface-enhanced Raman spectroscopy for ultra-sensitive detection of biological molecules.
Topics: Adenine; Biopolymers; Lithium Chloride; Microchemistry; Reproducibility of Results; Sensitivity and | 2004 |
Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs.
Topics: Adenine; Bacillus subtilis; Crystallography, X-Ray; Gene Expression Regulation, Bacterial; Guanine; | 2004 |
The experts speak. Studying the potential of tenofovir to prevent sexual transmission of HIV: first steps. Interview by Vicki Glaser.
Topics: Adenine; Communicable Disease Control; Female; HIV Infections; Humans; Male; Organophosphonates; Pri | 2005 |
Aggregation behaviors of gemini nucleotide at the air-water interface and in solutions induced by adenine-uracil interaction.
Topics: Adenine; Air; Cations; Molecular Structure; Nucleotides; Particle Size; Sensitivity and Specificity; | 2005 |
Accurate measurement of 15N-13C residual dipolar couplings in nucleic acids.
Topics: Adenine; Bacteriophage Pf1; Base Pairing; Base Sequence; Carbon Isotopes; Cytidine; Deuterium; Esche | 2005 |
Summaries for patients. Antiviral regimens for chronic hepatitis B virus infection.
Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; Decision Support Techniques; Hepatitis B e Antigen | 2005 |
Treatment alternatives for chronic hepatitis B virus infection: a cost-effectiveness analysis.
Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; Decision Support Techniques; Hepatitis B e Antigen | 2005 |
Isotope edited internal standard method for quantitative surface-enhanced Raman spectroscopy.
Topics: Adenine; Deuterium; Molecular Structure; Optics and Photonics; Reference Standards; Reproducibility | 2005 |
Simultaneous quantification of emtricitabine and tenofovir in human plasma using high-performance liquid chromatography after solid phase extraction.
Topics: Adenine; Chromatography, High Pressure Liquid; Deoxycytidine; Drug Stability; Emtricitabine; Humans; | 2005 |
Polymerase chain reaction inhibition assay documenting the amotosalen-based photochemical pathogen inactivation process of platelet concentrates.
Topics: Adenine; Bacterial Infections; Blood Banking; Blood Preservation; DNA Primers; DNA, Mitochondrial; E | 2005 |
Determination of adefovir in human plasma by liquid chromatography/tandem mass spectrometry: application to a pharmacokinetic study.
Topics: Adenine; Administration, Oral; Adult; Blood Chemical Analysis; Chromatography, High Pressure Liquid; | 2005 |
Spontaneous self-association of adenine and uracil in polycrystals from low temperature FTIR spectra in the range below 1000 cm(-1).
Topics: Adenine; Crystallography; Models, Molecular; Sensitivity and Specificity; Spectroscopy, Fourier Tran | 2005 |
Detection of chlorinated DNA and RNA nucleosides by HPLC coupled to tandem mass spectrometry as potential biomarkers of inflammation.
Topics: Adenine; Biomarkers; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cytosine; Deoxyadenosin | 2005 |
Sensitive assay for determining plasma tenofovir concentrations by LC/MS/MS.
Topics: Adenine; Calibration; Chromatography, High Pressure Liquid; HIV Infections; Humans; Mass Spectrometr | 2006 |
Sensitive line probe assay that simultaneously detects mutations conveying resistance to lamivudine and adefovir.
Topics: Adenine; Antiviral Agents; Base Sequence; DNA Probes; DNA, Viral; Drug Resistance, Viral; Genes, Vir | 2006 |
UV excitation thermal lens microscope for sensitive and nonlabeled detection of nonfluorescent molecules.
Topics: Adenine; Fluorenes; Lasers; Lenses; Microchip Analytical Procedures; Microscopy, Fluorescence; Pyren | 2006 |
A novel electrochemical biosensor for the detection of uric acid and adenine.
Topics: Adenine; Biosensing Techniques; Carbon; Electrochemistry; Electrodes; Nanotechnology; Sensitivity an | 2006 |
Detection of rtN236T and rtA181V/T mutations associated with resistance to adefovir dipivoxil in samples from patients with chronic hepatitis B virus infection by the INNO-LiPA HBV DR line probe assay (version 2).
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Genotype; Hepatitis B virus; Hepatiti | 2006 |
Development and validation of a sensitive LC-MS/MS method for the determination of adefovir in human serum and urine.
Topics: Adenine; Adult; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Humans; Male; Mas | 2006 |
Binding of adenine to Stx2, the protein toxin from Escherichia coli O157:H7.
Topics: Adenine; Binding Sites; Crystallography, X-Ray; Escherichia coli; Protein Subunits; Sensitivity and | 2006 |
Liquid chromatography-tandem mass spectrometric determination of tenofovir-diphosphate in human peripheral blood mononuclear cells.
Topics: Adenine; Chromatography, Liquid; Drug Stability; Humans; Leukocytes, Mononuclear; Organophosphonates | 2006 |
A rapid and sensitive real-time PCR assay for the K65R drug resistance mutation in SIV reverse transcriptase.
Topics: Adenine; Animals; Disease Models, Animal; Drug Resistance, Viral; Macaca; Microbial Sensitivity Test | 2006 |
In vitro evaluation of the anti-orf virus activity of alkoxyalkyl esters of CDV, cCDV and (S)-HPMPA.
Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Ecthyma, Contagious; Fibroblasts | 2007 |
Detection of functional ricin by immunoaffinity and liquid chromatography-tandem mass spectrometry.
Topics: Adenine; Bioterrorism; Chromatography, Affinity; Chromatography, Liquid; Peptide-N4-(N-acetyl-beta-g | 2007 |
COBAS AmpliPrep-COBAS TaqMan hepatitis B virus (HBV) test: a novel automated real-time PCR assay for quantification of HBV DNA in plasma.
Topics: Adenine; Antiviral Agents; Automation; Biopsy; DNA, Viral; Drug Resistance, Viral; Hepatitis B Surfa | 2007 |
Cyclin D1 guanine/adenine 870 polymorphism with altered protein expression is associated with genomic instability and aggressive clinical biology of esophageal adenocarcinoma.
Topics: Adenine; Adenocarcinoma; Adult; Aged; Biomarkers, Tumor; Biopsy, Needle; Cohort Studies; Cyclin D1; | 2007 |
Synthesis and antiviral evaluation of alkoxyalkyl-phosphate conjugates of cidofovir and adefovir.
Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cowpox; Cytomegalovirus Infections; Cytosine; Herpe | 2007 |
Relevance of a combined UV and single mass spectrometry detection for the determination of tenofovir in human plasma by HPLC in therapeutic drug monitoring.
Topics: Adenine; Calibration; Drug Monitoring; HIV Infections; Humans; Mass Spectrometry; Organophosphonates | 2007 |
Development of a sensitive and specific liquid chromatography/mass spectrometry method for the determination of tenofovir in human plasma.
Topics: Adenine; Calibration; Chromatography, Liquid; Drug Stability; Freezing; Humans; Molecular Structure; | 2007 |
Detection of picomole amounts of biological substrates by para-hydrogen-enhanced NMR methods in conjunction with a suitable receptor complex.
Topics: Adenine; DNA; Ligands; Magnetic Resonance Spectroscopy; Molecular Structure; Organic Chemicals; Puri | 2007 |
Room temperature ionic liquid as matrix medium for the determination of residual solvents in pharmaceuticals by static headspace gas chromatography.
Topics: Adenine; Analytic Sample Preparation Methods; Borates; Chromatography, Gas; Drug Contamination; Imid | 2007 |
Ultrasensitive electrochemical detection of proteins by amplification of aptamer-nanoparticle bio bar codes.
Topics: Adenine; Animals; Antibodies; Antigen-Antibody Reactions; Aptamers, Nucleotide; Cattle; Electrochemi | 2007 |
On the position of the potential wall in DFT temporary anion calculations.
Topics: Adenine; Anions; Guanine; Models, Chemical; Models, Molecular; Molecular Structure; Quantum Theory; | 2007 |
Electrochemical determination of HIV drug Abacavir based on its reduction.
Topics: Adenine; Adenosine Triphosphate; Anti-HIV Agents; Dideoxynucleosides; Electrochemistry; Electrodes; | 2008 |
Combined analysis of galectin-3 and BRAFV600E improves the accuracy of fine-needle aspiration biopsy with cytological findings suspicious for papillary thyroid carcinoma.
Topics: Adenine; Adenocarcinoma, Papillary; Amino Acid Substitution; Biopsy, Fine-Needle; Galectin 3; Humans | 2007 |
Monitoring of dimethyl sulphate-induced N3-methyladenine, N7-methylguanine and O(6)-methylguanine DNA adducts using reversed-phase high performance liquid chromatography and mass spectrometry.
Topics: Adenine; Animals; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Guanine; Male; Reference S | 2008 |
Evidence of complete cellular repair of 1,N6-ethenoadenine, a mutagenic and potential damage for human cancer, revealed by a novel method.
Topics: Adenine; Animals; Biological Assay; Cell Cycle; Cell Extracts; DNA; DNA Damage; DNA Repair; HCT116 C | 2008 |
Some properties of new DNA-specific bisbenzimidazole fluorochromes without a piperazine ring.
Topics: Adenine; Animals; Benzimidazoles; Bisbenzimidazole; Bromodeoxyuridine; DNA; Flow Cytometry; Fluoresc | 1993 |
Alkylation of purine bases with 3,4-epoxy-1-butene, a reactive metabolite of 1,3-butadiene.
Topics: Adenine; Alkylation; Butadienes; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Electrochem | 1994 |
Development of methods for measuring biological markers of formaldehyde exposure.
Topics: Adenine; Animals; Biomarkers; Cell Nucleus; Cells, Cultured; Chromatography, Gas; DNA; DNA Adducts; | 1994 |
Substitution of 2-aminoadenine and 5-methylcytosine for adenine and cytosine in hybridization probes increases the sensitivity of DNA fingerprinting.
Topics: 2-Aminopurine; 5-Methylcytosine; Adenine; Base Sequence; Blotting, Southern; Cytosine; DNA; DNA Fing | 1994 |
Base specificity and binding of anti-ss/dsDNA monoclonal antibody. Application to the determination of ssDNA.
Topics: Adenine; Animals; Antibodies, Antinuclear; Antibodies, Monoclonal; Antibody Specificity; Base Sequen | 1993 |
SARs are cis DNA elements of chromosome dynamics: synthesis of a SAR repressor protein.
Topics: Adenine; Amino Acid Sequence; Animals; Base Sequence; Cell Nucleus; Chromatin; Chromosomes; DNA; DNA | 1995 |
Pharmacological selectivity of the cloned human P2U-purinoceptor: potent activation by diadenosine tetraphosphate.
Topics: Adenine; Adenine Nucleotides; Astrocytoma; Cloning, Molecular; Dinucleoside Phosphates; Humans; Inos | 1995 |
Observation and prevention of an artefactual formation of oxidized DNA bases and nucleosides in the GC-EIMS method.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Artifacts; Chromatography, High Pressure Liquid; Cytosine; Deo | 1996 |
Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T cell antigen receptor on thymocytes: analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine (EHNA) and rolipram.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Animals; Antibodies, Monoclonal; Binding, Competitive; | 1996 |
Validation and steady-state analysis of a power-law model of purine metabolism in man.
Topics: Adenine; Adenine Phosphoribosyltransferase; Guanine; Humans; Hypoxanthine; Hypoxanthine Phosphoribos | 1997 |
Nonselective URA3 colony-color assay in yeast ade1 or ade2 mutants.
Topics: Adenine; Color; Fungal Proteins; Genes, Fungal; Mutation; Phenotype; Saccharomyces cerevisiae; Sensi | 1997 |
Regulation of CCR2 chemokine receptor mRNA stability.
Topics: Adenine; Cell Line; Dactinomycin; Drug Stability; Humans; Lipopolysaccharides; Monocytes; Protein Sy | 1997 |
Specific interaction of cytokinins and their analogs with rotenone-sensitive internal NADH dehydrogenase in potato tuber mitochondria.
Topics: Adenine; Cytokinins; Electron Transport; Insecticides; Mitochondria; NADH Dehydrogenase; Rotenone; S | 1997 |
Hybridization-AT-tailing (HybrAT) method for sensitive and strand-specific detection of DNA and RNA.
Topics: Adenine; Base Sequence; DNA; DNA-Directed DNA Polymerase; Hepatitis C; Hepatitis C Antibodies; Human | 1998 |
A rapid and sensitive method to measure the enzymatic activity of ribosome-inactivating proteins.
Topics: Adenine; Bacterial Toxins; Base Sequence; DNA; DNA Primers; Kinetics; N-Glycosyl Hydrolases; Plant L | 1998 |
Determination of ATP and its metabolites released from rat caudal artery by isocratic ion-pair reversed-phase high-performance liquid chromatography.
Topics: Acetaldehyde; Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arteries; Calibration | 1998 |
Enhanced 9-(2-phosphonylmethoxyethyl)adenine secretion by a specific, indomethacin-sensitive efflux pump in a mutant 9-(2-phosphonylmethoxyethyl)adenine-resistant human erythroleukemia K562 cell line.
Topics: Adenine; Adenine Nucleotides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Ant | 1998 |
Pattern of localization of primitive hematopoietic cells in vivo using a novel mouse model.
Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Autoradiography; Carbon Radioisotopes; Cell Sur | 1999 |
Detection and quantification of 1,N(6)-ethenoadenine in human placental DNA by mass spectrometry.
Topics: Adenine; Adult; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Female; Fluorescence; Gas Ch | 1999 |
Evaluation of the alkaline comet assay and urinary 3-methyladenine excretion for monitoring DNA damage in melanoma patients treated with dacarbazine and tamoxifen.
Topics: Adenine; Adult; Aged; Antineoplastic Agents, Alkylating; Comet Assay; Dacarbazine; DNA Damage; Femal | 2000 |
Improved and simplified liquid chromatographic assay for adefovir, a novel antiviral drug, in human plasma using derivatization with chloroacetaldehyde.
Topics: Acetaldehyde; Adenine; Antiviral Agents; Chemical Precipitation; Chromatography, Liquid; Drug Stabil | 1999 |
Sensitivity of human type II topoisomerases to DNA damage: stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesions.
Topics: Adenine; Alkylation; Apurinic Acid; Base Sequence; DNA; DNA Adducts; DNA Damage; DNA Repair; DNA Top | 2000 |
Determination of purines including 2,8-dihydroxyadenine in urine using capillary electrophoresis.
Topics: Adenine; Electrophoresis, Capillary; Humans; Purines; Reproducibility of Results; Sensitivity and Sp | 2000 |
Application of magdala red as a fluorescence probe in the determination of nucleic acids.
Topics: Adenine; Animals; Cattle; Cytosine; DNA; Fluorescent Dyes; Guanine; Indicators and Reagents; Naphtha | 2000 |
Identification of 1-adenine DNA adducts in workers occupationally exposed to styrene.
Topics: Adenine; Adult; Air Pollutants, Occupational; Animals; Biomarkers; DNA Adducts; Environmental Monito | 2001 |
Elimination voltammetry of adenine and cytosine mixtures.
Topics: Adenine; Calibration; Cytosine; Electrochemistry; Electrodes; Hydrogen-Ion Concentration; Mercury; M | 2001 |
A colorimetric assay for the quantitation of free adenine applied to determine the enzymatic activity of ribosome-inactivating proteins.
Topics: Adenine; Biological Assay; Colorimetry; Immunotoxins; Kinetics; N-Glycosyl Hydrolases; Plant Protein | 2002 |
Direct electrochemistry of cytochrome c at a glassy carbon electrode modified with single-wall carbon nanotubes.
Topics: Adenine; Animals; Cytochrome c Group; Electrochemistry; Electrodes; Horses; Hydrogen-Ion Concentrati | 2002 |
An integrated computational and laboratory approach for selective amplification of mRNAs containing the adenylate uridylate-rich element consensus sequence.
Topics: 3' Untranslated Regions; Adenine; Cell Line; Cloning, Molecular; Computational Biology; Consensus Se | 2002 |
Occurrence of H-ras codon 61 CAA to AAA mutation during mouse liver tumor progression.
Topics: Adenine; Animals; Benzo(a)pyrene; Carcinogens; Coal Tar; Codon; Cytosine; Disease Progression; Genes | 2002 |
Specificity and affinity of binding of phosphate-containing compounds to CheY protein.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Bacteria | 1992 |
Measurement of thyroid-stimulating immunoglobulins by incorporation of tritiated-adenine into intact FRTL-5 cells: a viable alternative to radioimmunoassay for the measurement of cAMP.
Topics: Adenine; Animals; Autoantibodies; Biological Assay; Cells, Cultured; Cyclic AMP; Epithelium; Graves | 1992 |
HPLC determination of adenine compounds as fluorescent derivatives in canine red blood cells.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine T | 1992 |
The precise radioimmunoassay of adenosine: minimization of sample collection artifacts and immunocrossreactivity.
Topics: Adenine; Adenosine; Artifacts; Automation; Chromatography, High Pressure Liquid; Cross Reactions; Hu | 1992 |
Specific diagnosis of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency in dried blood spots by a polymerase chain reaction (PCR) assay detecting a point-mutation (G985) in the MCAD gene.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Adenine; Base Sequence; DNA; Guanine; Humans; Lipid | 1991 |