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coumarin and Sensitivity and Specificity

coumarin has been researched along with Sensitivity and Specificity in 47 studies

2H-chromen-2-one: coumarin derivative

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"A new complex between coumarin-based ligand (CL) and copper ion has been prepared and applied to be an ON-OFF-ON reversible fluorescence chemosensor for the detection of Cys with high sensitivity and specificity."3.81A highly selective and sensitive ON-OFF-ON fluorescence chemosensor for cysteine detection in endoplasmic reticulum. ( Duan, C; Jia, H; Meng, Q; Succar, P; Zhang, R; Zhang, Z; Zhao, L, 2015)
"By identifying VTE recurrence risk in cancer patients with VTE, we may be able to tailor treatment, improving clinical outcomes while minimizing costs."2.77Development of a clinical prediction rule for risk stratification of recurrent venous thromboembolism in patients with cancer-associated venous thromboembolism. ( Carrier, M; Dao, V; Kovacs, MJ; Lazo-Langner, A; Lee, AY; Louzada, ML; Meyer, G; Ramsay, TO; Rodger, MA; Wells, PS; Zhang, J, 2012)
"Hydroxyl radicals were detected by spin trapping EPR, and effects of OH radical quenchers on kinetics suggest that the reaction is initiated by these radicals or their equivalents."1.35Characterization of an LED based photoreactor to degrade 4-chlorophenol in an aqueous medium using coumarin (C-343) sensitized TiO2. ( Achari, G; Ghosh, JP; Langford, CH, 2008)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (19.15)18.2507
2000's17 (36.17)29.6817
2010's21 (44.68)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nair, RR1
Raju, M1
Bhai, S1
Raval, IH1
Haldar, S1
Ganguly, B1
Chatterjee, PB1
Kim, JH1
Qu, P1
Ma, X1
Chen, W1
Zhu, D1
Bai, H1
Wei, X1
Chen, S1
Xu, M1
Xie, X1
Huo, F1
Chao, J1
Zhang, Y2
Yin, C1
Peng, MJ1
Yang, XF1
Yin, B1
Guo, Y1
Suzenet, F1
En, D1
Li, J1
Li, CW1
Duan, YW1
Yeo, SJ1
Huong, DT1
Han, JH1
Kim, JY1
Lee, WJ1
Shin, HJ1
Han, ET1
Park, H1
Yap, AC1
Mahamad, UA1
Lim, SY1
Kim, HJ2
Choo, YM1
Meng, Q1
Jia, H1
Succar, P1
Zhao, L1
Zhang, R1
Duan, C1
Zhang, Z2
Qin, JC1
Yang, ZY1
Ren, Z1
Nie, B1
Liu, T1
Yuan, F1
Feng, F1
Zhou, W1
Xu, X1
Yao, M1
Zhang, F1
Ghosh, JP1
Langford, CH1
Achari, G1
Roussakis, E1
Pergantis, SA1
Katerinopoulos, HE1
Poller, L1
Christensen, TD1
Larsen, TB1
Jensen, C1
Maegaard, M1
Sørensen, B1
Gupta, R1
Mishra, P1
Mittal, A1
Avila, M1
Zougagh, M1
Escarpa, A1
Ríos, A1
Ma, W1
Xu, Q1
Du, J1
Song, B1
Peng, X1
Wang, Z1
Li, G1
Wang, X2
Kwon, H1
Lee, K1
Shiraishi, Y1
Sumiya, S1
Hirai, T1
Tsukamoto, K1
Shinohara, Y1
Iwasaki, S1
Maeda, H1
Oliveira, E1
Nuñez, C1
Rodríguez-González, B1
Capelo, JL1
Lodeiro, C1
Uehara, S1
Murayama, N1
Nakanishi, Y1
Zeldin, DC1
Yamazaki, H2
Uno, Y1
Maity, D2
Govindaraju, T2
Yang, Z1
Liu, Z1
Chen, Y1
He, W1
Lu, Y1
Louzada, ML1
Carrier, M1
Lazo-Langner, A1
Dao, V1
Kovacs, MJ1
Ramsay, TO1
Rodger, MA1
Zhang, J1
Lee, AY1
Meyer, G1
Wells, PS1
Hou, JT1
Li, K1
Yu, KK1
Wu, MY1
Yu, XQ1
Jiao, CX1
Niu, CG1
Chen, LX1
Shen, GL1
Yu, RQ1
Vassallo, JD1
Morrall, SW1
Fliter, KL1
Curry, SM1
Daston, GP1
Lehman-McKeeman, LD1
Pashkova, A1
Moskovets, E1
Karger, BL1
Frosch, PJ2
Pirker, C2
Rastogi, SC2
Andersen, KE2
Bruze, M2
Svedman, C2
Goossens, A2
White, IR2
Uter, W2
Arnau, EG2
Lepoittevin, JP2
Menné, T2
Johansen, JD2
Brinkmeier, T1
Zhou, L1
Zhao, S1
Deng, H1
Deng, Q1
Vasylevska, AS1
Karasyov, AA1
Borisov, SM1
Krause, C1
Zinovev, AV1
Veryovkin, IV1
Moore, JF1
Pellin, MJ1
Lesner, A1
Wysocka, M1
Guzow, K1
Wiczk, W1
Legowska, A1
Rolka, K1
Zacharis, CK1
Raikos, N1
Giouvalakis, N1
Tsoukali-Papadopoulou, H1
Theodoridis, GA1
Lamiable, D1
Vistelle, R1
Trenque, T1
Fay, R1
Millart, H1
Choisy, H1
Cunningham, MT1
Olson, JD1
Balestrieri, C1
Camussi, G1
Giovane, A1
Iorio, EL1
Quagliuolo, L1
Servillo, L1
Mischke, R1
Bogan, DP1
O'Kennedy, R1
Ng, VL1
Valdes-Camin, R1
Gottfried, EL1
Echaves, SA1
Stead, AG1
Ebert, RF1
Tanaka, M1
Shimada, T1
Soucek, P1
Wongpraparut, N1
Apiyasawat, S1
Jacobs, LE1
Kotler, MN1
Knight, CG1
Willenbrock, F1
Murphy, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Analysis of Pro-coagulant and Thrombin-generation Markers for the Prediction of Therapeutic Failure in Cancer Patients at Risk for Recurrence of Venous Thromboembolism: A Pilot Study[NCT01602445]700 participants (Anticipated)Observational2012-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for coumarin and Sensitivity and Specificity

ArticleYear
Development of a clinical prediction rule for risk stratification of recurrent venous thromboembolism in patients with cancer-associated venous thromboembolism.
    Circulation, 2012, Jul-24, Volume: 126, Issue:4

    Topics: Anticoagulants; Cohort Studies; Coumarins; Decision Support Techniques; Female; Heparin, Low-Molecul

2012

Other Studies

46 other studies available for coumarin and Sensitivity and Specificity

ArticleYear
Estimation of bisulfate in edible plant foods, dog urine, and drugs: picomolar level detection and bio-imaging in living organisms.
    The Analyst, 2019, Sep-23, Volume: 144, Issue:19

    Topics: Alanine; Animals; Artemia; Bacteria; Coumarins; Dogs; Fluorescent Dyes; Food Analysis; Glycine; Huma

2019
Extraction time and temperature affect the extraction efficiencies of coumarin and phenylpropanoids from Cinnamomum cassia bark using a microwave-assisted extraction method.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017, Sep-15, Volume: 1063

    Topics: Acrolein; Chemical Fractionation; Chromatography, High Pressure Liquid; Cinnamates; Cinnamomum aroma

2017
A coumarin-based fluorescent probe for ratiometric detection of hydrazine and its application in living cells.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2019, Mar-05, Volume: 210

    Topics: Acetates; Buffers; Chlorides; Coumarins; Fluorescent Dyes; Fluorometry; HeLa Cells; Humans; Hydrazin

2019
A dual electron-withdrawing enhanced selective/sensitive chemodosimeter for detection on bisulfate and its living cell imaging.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2019, Sep-05, Volume: 220

    Topics: Acetates; Coumarins; Electrons; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen-Ion Concentration; Li

2019
A hybrid coumarin-thiazole fluorescent sensor for selective detection of bisulfite anions in vivo and in real samples.
    Chemistry, an Asian journal, 2014, Volume: 9, Issue:7

    Topics: Anions; Biosensing Techniques; Color; Coumarins; Female; Fluorescent Dyes; Humans; MCF-7 Cells; Mole

2014
Performance of coumarin-derived dendrimer-based fluorescence-linked immunosorbent assay (FLISA) to detect malaria antigen.
    Malaria journal, 2014, Jul-10, Volume: 13

    Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antibodies, Protozoan; Antigens, Protozoan; Coumarins;

2014
A coumarin-based fluorescent probe as a central nervous system disease biomarker.
    Sensors (Basel, Switzerland), 2014, Nov-10, Volume: 14, Issue:11

    Topics: Biomarkers; Biosensing Techniques; Coumarins; Fluorescent Dyes; Homocysteine; Humans; Methylmalonic

2014
A highly selective and sensitive ON-OFF-ON fluorescence chemosensor for cysteine detection in endoplasmic reticulum.
    Biosensors & bioelectronics, 2015, Dec-15, Volume: 74

    Topics: Biosensing Techniques; Cell Line; Copper; Coumarins; Cysteine; Endoplasmic Reticulum; Equipment Desi

2015
Design of a novel coumarin-based multifunctional fluorescent probe for Zn²⁺/Cu²⁺/S²⁻ in aqueous solution.
    Materials science & engineering. C, Materials for biological applications, 2015, Dec-01, Volume: 57

    Topics: Copper; Coumarins; Environmental Monitoring; Fluorescent Dyes; Molecular Probe Techniques; Reproduci

2015
Simultaneous Determination of Coumarin and Its Derivatives in Tobacco Products by Liquid Chromatography-Tandem Mass Spectrometry.
    Molecules (Basel, Switzerland), 2016, Nov-10, Volume: 21, Issue:11

    Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Coumarins; Flavoring Agents; Molecular

2016
Characterization of an LED based photoreactor to degrade 4-chlorophenol in an aqueous medium using coumarin (C-343) sensitized TiO2.
    The journal of physical chemistry. A, 2008, Oct-16, Volume: 112, Issue:41

    Topics: Catalysis; Chlorophenols; Coloring Agents; Coumarins; Electron Spin Resonance Spectroscopy; Hydroxyl

2008
Coumarin-based ratiometric fluorescent indicators with high specificity for lead ions.
    Chemical communications (Cambridge, England), 2008, Dec-14, Issue:46

    Topics: Alkenes; Amines; Catalysis; Coumarins; Fluorescent Dyes; Gold; Hydrogen; Ions; Lead; Molecular Struc

2008
Precision and accuracy of CoaguChek S and XS monitors: the need for external quality assessment.
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:3

    Topics: Anticoagulants; Calibration; Coumarins; Drug Monitoring; Evaluation Studies as Topic; Humans; Intern

2009
International normalised ratio (INR) measured on the CoaguChek S and XS compared with the laboratory for determination of precision and accuracy.
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:3

    Topics: Aged; Anticoagulants; Coumarins; Drug Monitoring; Female; Humans; International Normalized Ratio; Ma

2009
Enhancing nucleic acid detection sensitivity of propidium iodide by a three nanometer interaction inside cells and in solutions.
    Journal of nanoscience and nanotechnology, 2009, Volume: 9, Issue:4

    Topics: Cell Membrane Permeability; Coumarins; Drug Delivery Systems; Fluorescence Resonance Energy Transfer

2009
Determination of alkenylbenzenes and related flavour compounds in food samples by on-column preconcentration-capillary liquid chromatography.
    Journal of chromatography. A, 2009, Oct-23, Volume: 1216, Issue:43

    Topics: Allylbenzene Derivatives; Anisoles; Benzene Derivatives; Benzyl Compounds; Chromatography, Liquid; C

2009
A Hg2+-selective chemodosimeter based on desulfurization of coumarin thiosemicarbazide in aqueous media.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2010, Volume: 76, Issue:2

    Topics: Coumarins; Mercury; Semicarbazides; Sensitivity and Specificity; Spectrometry, Fluorescence

2010
Coumarin-malonitrile conjugate as a fluorescence turn-on probe for biothiols and its cellular expression.
    Chemical communications (Cambridge, England), 2011, Feb-14, Volume: 47, Issue:6

    Topics: Coumarins; Cysteine; Fluorescence; Fluorescent Dyes; Glutathione; Homocysteine; Molecular Probes; Ni

2011
Highly sensitive cyanide anion detection with a coumarin-spiropyran conjugate as a fluorescent receptor.
    Chemical communications (Cambridge, England), 2011, May-07, Volume: 47, Issue:17

    Topics: Anions; Benzopyrans; Chemistry Techniques, Analytical; Coumarins; Cyanides; Fluorescence; Indoles; M

2011
A coumarin-based fluorescent probe for Hg2+ and Ag+ with an N'-acetylthioureido group as a fluorescence switch.
    Chemical communications (Cambridge, England), 2011, May-07, Volume: 47, Issue:17

    Topics: Acetylation; Acids; Buffers; Coumarins; Fluorescence; Fluorescent Dyes; Hydrogen Bonding; Hydrogen-I

2011
Novel small stable gold nanoparticles bearing fluorescent cysteine-coumarin probes as new metal-modulated chemosensors.
    Inorganic chemistry, 2011, Sep-19, Volume: 50, Issue:18

    Topics: Coumarins; Crystallography, X-Ray; Cysteine; Fluorescent Dyes; Gold; Mercury; Metals; Models, Molecu

2011
Immunochemical detection of cytochrome P450 enzymes in liver microsomes of 27 cynomolgus monkeys.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:2

    Topics: Animals; Anticoagulants; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP3A; Cytochrom

2011
Highly selective colorimetric chemosensor for Co2+.
    Inorganic chemistry, 2011, Nov-21, Volume: 50, Issue:22

    Topics: Biosensing Techniques; Cations, Divalent; Cobalt; Colorimetry; Coloring Agents; Coumarins; Escherich

2011
A differentially selective sensor with fluorescence turn-on response to Zn2+ and dual-mode ratiometric response to Al3+ in aqueous media.
    Chemical communications (Cambridge, England), 2012, Jan-25, Volume: 48, Issue:7

    Topics: Aluminum; Cations; Coumarins; Fluorescent Dyes; Quinolines; Sensitivity and Specificity; Spectrometr

2012
A new ratiometric and colorimetric chemosensor for cyanide anion based on coumarin-hemicyanine hybrid.
    Organic & biomolecular chemistry, 2012, Jul-14, Volume: 10, Issue:26

    Topics: Anions; Colorimetry; Coloring Agents; Coumarins; Cyanides; Models, Molecular; Sensitivity and Specif

2012
Coumarin-DPA-Cu(II) as a chemosensing ensemble towards histidine determination in urine and serum.
    Organic & biomolecular chemistry, 2013, Feb-07, Volume: 11, Issue:5

    Topics: Amines; Animals; Copper; Coumarins; Fluorescent Dyes; Histidine; Humans; Picolinic Acids; Sensitivit

2013
A coumarin derivative covalently immobilized on sensing membrane as a fluorescent carrier for nitrofurazone.
    Analytical and bioanalytical chemistry, 2003, Volume: 376, Issue:3

    Topics: Coumarins; Fluorescent Dyes; Hydrogen-Ion Concentration; Membranes, Artificial; Nitrofurazone; Repro

2003
Liquid chromatographic determination of the glutathione conjugate and ring-opened metabolites formed from coumarin epoxidation.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Sep-05, Volume: 794, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Coumarins; Epoxy Compounds; Glutathione; Magnetic Res

2003
Coumarin tags for improved analysis of peptides by MALDI-TOF MS and MS/MS. 1. Enhancement in MALDI MS signal intensities.
    Analytical chemistry, 2004, Aug-01, Volume: 76, Issue:15

    Topics: Amino Acid Sequence; Coumarins; Mass Spectrometry; Molecular Sequence Data; Peptides; Protein Bindin

2004
Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix.
    Contact dermatitis, 2005, Volume: 52, Issue:4

    Topics: Acrolein; Acyclic Monoterpenes; Adolescent; Adult; Aged; Aged, 80 and over; Aldehydes; Allergens; Co

2005
Patch testing with a new fragrance mix - reactivity to the individual constituents and chemical detection in relevant cosmetic products.
    Contact dermatitis, 2005, Volume: 52, Issue:4

    Topics: Acrolein; Acyclic Monoterpenes; Adolescent; Adult; Aged; Aged, 80 and over; Aldehydes; Allergens; Co

2005
3-Hydroxycoumarin as a new matrix for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of DNA.
    Journal of the American Society for Mass Spectrometry, 2006, Volume: 17, Issue:12

    Topics: Base Sequence; Coumarins; DNA; Molecular Sequence Data; Sensitivity and Specificity; Sequence Analys

2006
Novel coumarin-based fluorescent pH indicators, probes and membranes covering a broad pH range.
    Analytical and bioanalytical chemistry, 2007, Volume: 387, Issue:6

    Topics: Coumarins; Hydrogen-Ion Concentration; Molecular Structure; Photochemistry; Sensitivity and Specific

2007
Laser-driven acoustic desorption of organic molecules from back-irradiated solid foils.
    Analytical chemistry, 2007, Nov-01, Volume: 79, Issue:21

    Topics: Anthracenes; Coumarins; Fluorescein; Fluorescent Dyes; Lasers; Metals; Molecular Structure; Photons;

2007
Development of sensitive cathepsin G fluorogenic substrate using combinatorial chemistry methods.
    Analytical biochemistry, 2008, Apr-15, Volume: 375, Issue:2

    Topics: Absorption; Acetic Acid; Amino Acid Sequence; Cathepsin G; Cathepsins; Combinatorial Chemistry Techn

2008
A new method for the HPLC determination of gamma-hydroxybutyric acid (GHB) following derivatization with a coumarin analogue and fluorescence detection: application in the analysis of biological fluids.
    Talanta, 2008, Apr-15, Volume: 75, Issue:2

    Topics: Chromatography, High Pressure Liquid; Coumarins; Humans; Hydroxybutyrates; Saliva; Sensitivity and S

2008
Sensitive high-performance liquid chromatographic method for the determination of coumarin in plasma.
    Journal of chromatography, 1993, Oct-29, Volume: 620, Issue:2

    Topics: Calibration; Chromatography, High Pressure Liquid; Coumarins; Humans; Male; Reproducibility of Resul

1993
Low interinstrument variability of the international normalized ratio with the coagamate X2/Simplastin excel system.
    American journal of clinical pathology, 1996, Volume: 105, Issue:3

    Topics: Anticoagulants; Blood Coagulation Tests; Calibration; Coumarins; Humans; Prothrombin Time; Reference

1996
Measurement of platelet-activating factor acetylhydrolase activity by quantitative high-performance liquid chromatography determination of coumarin-derivatized 1-O-alkyl-2-sn-lysoglyceryl-3-phosphorylcholine.
    Analytical biochemistry, 1996, Jan-15, Volume: 233, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Chromatography, High Pressure Liquid; Coumarins; Fem

1996
Evaluation of a prothrombin time optimized for the dog on plasmas with defined coagulation factor deficiency due to coumarin intoxication.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1995, Volume: 42, Issue:9

    Topics: Animals; Blood Coagulation Disorders; Coumarins; Dog Diseases; Dogs; Female; Humans; Male; Pregnancy

1995
Simultaneous determination of coumarin, 7-hydroxycoumarin and 7-hydroxycoumarin glucuronide in human serum and plasma by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical applications, 1996, Nov-15, Volume: 686, Issue:2

    Topics: Chromatography, High Pressure Liquid; Coumarins; Humans; Sensitivity and Specificity; Spectrophotome

1996
Highly sensitive thromboplastins do not improve INR precision.
    American journal of clinical pathology, 1998, Volume: 109, Issue:3

    Topics: Anticoagulants; Coumarins; Humans; Indicators and Reagents; Multivariate Analysis; Prothrombin Time;

1998
Highly sensitive high-performance liquid chromatographic assay for coumarin 7-hydroxylation and 7-ethoxycoumarin O-deethylation by human liver cytochrome P450 enzymes.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Jan-08, Volume: 721, Issue:1

    Topics: Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 Enzyme System; Humans; Isoenzymes;

1999
Novel sensitive high-performance liquid chromatographic method for assay of coumarin 7-hydroxylation.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Oct-29, Volume: 734, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Coumarins; Cytochrome

1999
Biventricular thrombi.
    Echocardiography (Mount Kisco, N.Y.), 2001, Volume: 18, Issue:7

    Topics: Aged; Coumarins; Echocardiography; Female; Follow-Up Studies; Heart Diseases; Heparin; Humans; Sensi

2001
A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases.
    FEBS letters, 1992, Jan-27, Volume: 296, Issue:3

    Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Coumarins; Extracellular Matrix; Humans;

1992