cetirizine has been researched along with Sensitivity and Specificity in 21 studies
Cetirizine: A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.
cetirizine : A member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The method described herein has been first used to reveal the pharmacokinetic characters in healthy Chinese volunteers treated with oral administration of different dosages of cetirizine dihydrochloride and controlled-released pseudoephedrine hydrochloride compound tablet, and approached the influence of a standard meal on the extent and rate of absorption of the combination tablet." | 2.73 | Development and evaluation of an efficient HPLC/MS/MS method for the simultaneous determination of pseudoephedrine and cetirizine in human plasma: application to phase-I pharmacokinetic study. ( Cui, S; Feng, F; Liu, H; Ma, M; Sheng, Y, 2007) |
| " Validation results on linearity, specificity, accuracy, precision and stability, as well as its application to the analysis of plasma samples taken up to 48h after oral administration of 5mg of levocetirizine dichloridrate in healthy volunteers demonstrate its applicability to bioavailability studies." | 2.73 | Determination of levocetirizine in human plasma by liquid chromatography-electrospray tandem mass spectrometry: application to a bioequivalence study. ( Abib, E; Amarante, AR; Barros, FA; Berton, D; Boldin, R; Calafatti, SA; Campos, DR; Meurer, EC; Morita, MR; Pedrazolli, J; Pereira, R, 2008) |
| "Carbamazepine is an anticonvulsant requiring routine therapeutic drug monitoring." | 1.36 | Analytical performance evaluation of ADVIA Chemistry Carbamazepine_2 assay: minimal cross-reactivity with carbamazepine 10, 11-epoxide and none with hydroxyzine or cetirizine. ( Dasgupta, A; Davis, BG; Johnson, M; Marlow, AM; Reyes, MA, 2010) |
| "Levocetirizine-D(8) was used as an internal standard (IS)." | 1.36 | Enantioselective determination of cetirizine in human plasma by normal-phase liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry. ( Han, SB; Jang, HJ; Kang, SW; Kim, KA; Moore, VS; Park, JY; Youm, JR, 2010) |
| "The objective of the current study was to develop a simple, accurate, precise and rapid reversed-phase HPLC method and subsequent validation using ICH suggested approach for the determination of antihistaminic-decongestant pharmaceutical dosage forms containing binary mixtures of pseudoephedrine hydrochloride (PSE) with fexofenadine hydrochloride (FEX) or cetirizine dihydrochloride (CET)." | 1.35 | Development and validation of a rapid RP-HPLC method for the determination of cetirizine or fexofenadine with pseudoephedrine in binary pharmaceutical dosage forms. ( Karakuş, S; Küçükgüzel, I; Küçükgüzel, SG, 2008) |
| "Isoniazid was extracted from animal plasma samples using a Waters Oasis HLB 96-well plate and then eluted with acetonitrile, while cetirizine was extracted from human plasma with a Waters MCX mu-Elute plate and then eluted with acetonitrile containing 5% concentrated ammonium hydroxide." | 1.32 | Direct injection of solid-phase extraction eluents onto silica columns for the analysis of polar compounds isoniazid and cetirizine in plasma using hydrophilic interaction chromatography with tandem mass spectrometry. ( Bryant, MS; Jiang, XY; Junga, H; Li, AC; Naidong, W; Shou, WZ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 13 (61.90) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wolanczyk-Medrala, A | 1 |
| Gogolewski, G | 1 |
| Liebhart, J | 1 |
| Gomulka, K | 1 |
| Litwa, M | 1 |
| Panaszek, B | 1 |
| Lindner, K | 1 |
| Medrala, W | 1 |
| Dasgupta, A | 1 |
| Reyes, MA | 1 |
| Davis, BG | 1 |
| Marlow, AM | 1 |
| Johnson, M | 1 |
| Kang, SW | 1 |
| Jang, HJ | 1 |
| Moore, VS | 1 |
| Park, JY | 1 |
| Kim, KA | 1 |
| Youm, JR | 1 |
| Han, SB | 1 |
| Nojavan, S | 1 |
| Fakhari, AR | 1 |
| Andrade, P | 1 |
| Brinca, A | 1 |
| Gonçalo, M | 1 |
| Flynn, CA | 1 |
| Alnouti, Y | 1 |
| Reed, GA | 1 |
| Dharuman, J | 1 |
| Vasudhevan, M | 1 |
| Ajithlal, T | 1 |
| Ryu, JK | 1 |
| Yoo, SD | 1 |
| Li, AC | 2 |
| Junga, H | 2 |
| Shou, WZ | 1 |
| Bryant, MS | 1 |
| Jiang, XY | 1 |
| Naidong, W | 2 |
| Song, Q | 1 |
| Tang, Y | 1 |
| Addison, T | 1 |
| McCort-Tipton, M | 1 |
| Beato, B | 1 |
| Likar, MD | 1 |
| Mansour, HL | 1 |
| Harwood, JW | 1 |
| Tan, ZR | 1 |
| Ouyang, DS | 1 |
| Zhou, G | 1 |
| Wang, LS | 1 |
| Li, Z | 1 |
| Wang, D | 1 |
| Zhou, HH | 1 |
| Ma, M | 1 |
| Feng, F | 1 |
| Sheng, Y | 1 |
| Cui, S | 1 |
| Liu, H | 1 |
| Kowalski, P | 1 |
| Plenis, A | 1 |
| Hammad, SF | 1 |
| Mabrouk, MM | 1 |
| Habib, A | 1 |
| Elfatatry, H | 1 |
| Kishikawa, N | 1 |
| Nakashima, K | 1 |
| Kuroda, N | 1 |
| Karakuş, S | 1 |
| Küçükgüzel, I | 1 |
| Küçükgüzel, SG | 1 |
| Morita, MR | 1 |
| Berton, D | 1 |
| Boldin, R | 1 |
| Barros, FA | 1 |
| Meurer, EC | 1 |
| Amarante, AR | 1 |
| Campos, DR | 1 |
| Calafatti, SA | 1 |
| Pereira, R | 1 |
| Abib, E | 1 |
| Pedrazolli, J | 1 |
| Macek, J | 1 |
| Ptácek, P | 1 |
| Klíma, J | 1 |
| Zaater, MF | 1 |
| Tahboub, YR | 1 |
| Najib, NM | 1 |
| Gowda, BG | 1 |
| Melwanki, MB | 1 |
| Seetharamappa, J | 1 |
| de Jager, AD | 1 |
| Hundt, HK | 1 |
| Swart, KJ | 1 |
| Hundt, AF | 1 |
| Els, J | 1 |
2 trials available for cetirizine and Sensitivity and Specificity
| Article | Year |
|---|---|
Development and evaluation of an efficient HPLC/MS/MS method for the simultaneous determination of pseudoephedrine and cetirizine in human plasma: application to phase-I pharmacokinetic study.
Topics: Adult; Calibration; Cetirizine; Chromatography, High Pressure Liquid; Ephedrine; Female; Humans; Mal | 2007 |
Determination of levocetirizine in human plasma by liquid chromatography-electrospray tandem mass spectrometry: application to a bioequivalence study.
Topics: Adolescent; Adult; Biological Availability; Cetirizine; Cross-Over Studies; Histamine H1 Antagonists | 2008 |
19 other studies available for cetirizine and Sensitivity and Specificity
| Article | Year |
|---|---|
A new variant of the basophil activation test for allergen-induced basophil CD63 upregulation. The effect of cetirizine.
Topics: Adult; Animals; Antigens, CD; Antigens, Dermatophagoides; Antigens, Plant; Basophil Degranulation Te | 2009 |
Analytical performance evaluation of ADVIA Chemistry Carbamazepine_2 assay: minimal cross-reactivity with carbamazepine 10, 11-epoxide and none with hydroxyzine or cetirizine.
Topics: Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Cetirizine; Drug Monitoring; Humans; Hydrox | 2010 |
Enantioselective determination of cetirizine in human plasma by normal-phase liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry.
Topics: Cetirizine; Chromatography, High Pressure Liquid; Drug Stability; Histamine H1 Antagonists, Non-Seda | 2010 |
Chiral separation and quantitation of cetirizine and hydroxyzine by maltodextrin-mediated CE in human plasma: effect of zwitterionic property of cetirizine on enantioseparation.
Topics: Cetirizine; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Hydroxyzine; Linear Mode | 2011 |
Patch testing in fixed drug eruptions--a 20-year review.
Topics: Acetaminophen; Adult; Aged; Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroi | 2011 |
Quantification of the transporter substrate fexofenadine in cell lysates by liquid chromatography/tandem mass spectrometry.
Topics: Cell Extracts; Cetirizine; Chromatography, Liquid; HEK293 Cells; Humans; Least-Squares Analysis; Rep | 2011 |
High performance liquid chromatographic method for the determination of cetirizine and ambroxol in human plasma and urine--a boxcar approach.
Topics: Adult; Ambroxol; Analysis of Variance; Cetirizine; Chromatography, High Pressure Liquid; Drug Stabil | 2011 |
Simultaneous determination of levocetirizine and pseudoephedrine in dog plasma by liquid chromatography-mass spectrometry in the presence of dextrocetirizine.
Topics: Administration, Oral; Animals; Calibration; Cetirizine; Chromatography, Liquid; Diazepam; Dogs; Male | 2012 |
Direct injection of solid-phase extraction eluents onto silica columns for the analysis of polar compounds isoniazid and cetirizine in plasma using hydrophilic interaction chromatography with tandem mass spectrometry.
Topics: Animals; Blood Chemical Analysis; Cetirizine; Chromatography, High Pressure Liquid; Dogs; Flow Injec | 2004 |
Automated 96-well solid phase extraction and hydrophilic interaction liquid chromatography-tandem mass spectrometric method for the analysis of cetirizine (ZYRTEC) in human plasma--with emphasis on method ruggedness.
Topics: Cetirizine; Chromatography, High Pressure Liquid; Histamine H1 Antagonists; Humans; Mass Spectrometr | 2005 |
Development and validation of a dissolution test for a once-a-day combination tablet of immediate-release cetirizine dihydrochloride and extended-release pseudoephedrine hydrochloride.
Topics: Biological Availability; Cetirizine; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid | 2005 |
Sensitive bioassay for the simultaneous determination of pseudoephedrine and cetirizine in human plasma by liquid-chromatography-ion trap spectrometry.
Topics: Adult; Anti-Allergic Agents; Cetirizine; Chromatography, Liquid; Drug Combinations; Ephedrine; Human | 2006 |
Comparison of HPLC and CE methods for the determination of cetirizine dihydrochloride in human plasma samples.
Topics: Calibration; Cetirizine; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Humans; R | 2007 |
Precolumn fluorescence labeling method for simultaneous determination of hydroxyzine and cetirizine in human serum.
Topics: Boronic Acids; Cetirizine; Chromatography, High Pressure Liquid; Drug Monitoring; Fluorescent Dyes; | 2007 |
Development and validation of a rapid RP-HPLC method for the determination of cetirizine or fexofenadine with pseudoephedrine in binary pharmaceutical dosage forms.
Topics: Cetirizine; Chromatography, High Pressure Liquid; Dosage Forms; Histamine H1 Antagonists; Pharmaceut | 2008 |
Determination of cetirizine in human plasma by high-performance liquid chromatography.
Topics: Cetirizine; Chromatography, High Pressure Liquid; Drug Stability; Freezing; Histamine H1 Antagonists | 1999 |
RP-LC method for the determination of cetirizine in serum.
Topics: Cetirizine; Chromatography, High Pressure Liquid; Histamine H1 Antagonists; Humans; Reproducibility | 2000 |
Extractive spectrophotometric determination of ceterizine HCl in pharmaceutical preparations.
Topics: Anti-Allergic Agents; Artifacts; Bromcresol Purple; Bromphenol Blue; Cetirizine; Pharmaceutical Prep | 2001 |
Extractionless and sensitive method for high-throughput quantitation of cetirizine in human plasma samples by liquid chromatography-tandem mass spectrometry.
Topics: Cetirizine; Chromatography, Liquid; Histamine H1 Antagonists; Humans; Mass Spectrometry; Reference S | 2002 |