phenoxybenzamine has been researched along with Sensitivity and Specificity in 7 studies
Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Excerpt | Relevance | Reference |
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"We assessed the sensitivity and specificity of glucagon stimulation and clonidine suppression tests in the diagnosis of pheochromocytoma in 113 hypertensive patients, 39 with and 74 without the tumor." | 7.68 | Glucagon and clonidine testing in the diagnosis of pheochromocytoma. ( Goldstein, DS; Grossman, E; Hoffman, A; Keiser, HR, 1991) |
"We assessed the sensitivity and specificity of glucagon stimulation and clonidine suppression tests in the diagnosis of pheochromocytoma in 113 hypertensive patients, 39 with and 74 without the tumor." | 3.68 | Glucagon and clonidine testing in the diagnosis of pheochromocytoma. ( Goldstein, DS; Grossman, E; Hoffman, A; Keiser, HR, 1991) |
"Phenoxybenzamine is a beta-haloalkylamine which alkylates chemically active radicals such as hydroxy, sulfhydryl, and amino groups." | 1.28 | Phenoxybenzamine selectively and irreversibly inactivates dopaminergic D2 receptors on primary cultured rat lactotrophs. ( Heisler, RL; McAssey, K; Shin, SH; Szabo, MS, 1992) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (28.57) | 18.2507 |
2000's | 3 (42.86) | 29.6817 |
2010's | 2 (28.57) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chung, FH | 1 |
Chiang, YR | 1 |
Tseng, AL | 1 |
Sung, YC | 1 |
Lu, J | 1 |
Huang, MC | 1 |
Ma, N | 1 |
Lee, HC | 1 |
Pai, RK | 1 |
Conant, AR | 1 |
Dihmis, WC | 1 |
Yau, JS | 1 |
Li, JK | 1 |
Tam, VH | 1 |
Fung, LM | 1 |
Yeung, CK | 1 |
Chan, KW | 1 |
Lee, KM | 1 |
Lee, KF | 1 |
Cheung, WS | 1 |
Yeung, VT | 1 |
Yuen, YP | 1 |
Kwan, WK | 1 |
Corvera, JS | 1 |
Morris, CD | 1 |
Budde, JM | 1 |
Velez, DA | 1 |
Puskas, JD | 1 |
Lattouf, OM | 1 |
Cooper, WA | 1 |
Guyton, RA | 1 |
Vinten-Johansen, J | 1 |
Chung, AW | 1 |
Rauniyar, P | 1 |
Luo, H | 1 |
Hsiang, YN | 1 |
van Breemen, C | 1 |
Okon, EB | 1 |
Shin, SH | 1 |
McAssey, K | 1 |
Heisler, RL | 1 |
Szabo, MS | 1 |
Grossman, E | 1 |
Goldstein, DS | 1 |
Hoffman, A | 1 |
Keiser, HR | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Diagnosis and Treatment of Pheochromocytoma[NCT00001229] | 240 participants | Observational | 1988-10-31 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
7 other studies available for phenoxybenzamine and Sensitivity and Specificity
Article | Year |
---|---|
Functional Module Connectivity Map (FMCM): a framework for searching repurposed drug compounds for systems treatment of cancer and an application to colorectal adenocarcinoma.
Topics: Adenocarcinoma; Algorithms; Colorectal Neoplasms; Drug Repositioning; Epistasis, Genetic; Ethacrynic | 2014 |
Treatment with phenoxybenzamine may lead to loss of endothelial viability in radial artery.
Topics: Coronary Artery Bypass; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Follow-Up S | 2008 |
Phaeochromocytoma in the Hong Kong Chinese population.
Topics: 3-Iodobenzylguanidine; Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Catecholamines; Female; Fol | 2010 |
Pretreatment with phenoxybenzamine attenuates the radial artery's vasoconstrictor response to alpha-adrenergic stimuli.
Topics: Adrenergic alpha-Antagonists; Case-Control Studies; Coronary Artery Bypass; Coronary Disease; Female | 2003 |
Pressure distention compared with pharmacologic relaxation in vein grafting upregulates matrix metalloproteinase-2 and -9.
Topics: Animals; Biomarkers; Biopsy, Needle; Blotting, Western; Carotid Stenosis; Dilatation, Pathologic; Di | 2005 |
Phenoxybenzamine selectively and irreversibly inactivates dopaminergic D2 receptors on primary cultured rat lactotrophs.
Topics: Animals; Cells, Cultured; Male; Phenoxybenzamine; Pituitary Gland, Anterior; Prolactin; Rats; Rats, | 1992 |
Glucagon and clonidine testing in the diagnosis of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Catechols; Clonidine; Drug Therapy, Combination; Glucagon; Humans; Hyperten | 1991 |