Page last updated: 2024-11-02

phenoxybenzamine and Sensitivity and Specificity

phenoxybenzamine has been researched along with Sensitivity and Specificity in 7 studies

Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"We assessed the sensitivity and specificity of glucagon stimulation and clonidine suppression tests in the diagnosis of pheochromocytoma in 113 hypertensive patients, 39 with and 74 without the tumor."7.68Glucagon and clonidine testing in the diagnosis of pheochromocytoma. ( Goldstein, DS; Grossman, E; Hoffman, A; Keiser, HR, 1991)
"We assessed the sensitivity and specificity of glucagon stimulation and clonidine suppression tests in the diagnosis of pheochromocytoma in 113 hypertensive patients, 39 with and 74 without the tumor."3.68Glucagon and clonidine testing in the diagnosis of pheochromocytoma. ( Goldstein, DS; Grossman, E; Hoffman, A; Keiser, HR, 1991)
"Phenoxybenzamine is a beta-haloalkylamine which alkylates chemically active radicals such as hydroxy, sulfhydryl, and amino groups."1.28Phenoxybenzamine selectively and irreversibly inactivates dopaminergic D2 receptors on primary cultured rat lactotrophs. ( Heisler, RL; McAssey, K; Shin, SH; Szabo, MS, 1992)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chung, FH1
Chiang, YR1
Tseng, AL1
Sung, YC1
Lu, J1
Huang, MC1
Ma, N1
Lee, HC1
Pai, RK1
Conant, AR1
Dihmis, WC1
Yau, JS1
Li, JK1
Tam, VH1
Fung, LM1
Yeung, CK1
Chan, KW1
Lee, KM1
Lee, KF1
Cheung, WS1
Yeung, VT1
Yuen, YP1
Kwan, WK1
Corvera, JS1
Morris, CD1
Budde, JM1
Velez, DA1
Puskas, JD1
Lattouf, OM1
Cooper, WA1
Guyton, RA1
Vinten-Johansen, J1
Chung, AW1
Rauniyar, P1
Luo, H1
Hsiang, YN1
van Breemen, C1
Okon, EB1
Shin, SH1
McAssey, K1
Heisler, RL1
Szabo, MS1
Grossman, E1
Goldstein, DS1
Hoffman, A1
Keiser, HR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Diagnosis and Treatment of Pheochromocytoma[NCT00001229]240 participants Observational1988-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for phenoxybenzamine and Sensitivity and Specificity

ArticleYear
Functional Module Connectivity Map (FMCM): a framework for searching repurposed drug compounds for systems treatment of cancer and an application to colorectal adenocarcinoma.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Algorithms; Colorectal Neoplasms; Drug Repositioning; Epistasis, Genetic; Ethacrynic

2014
Treatment with phenoxybenzamine may lead to loss of endothelial viability in radial artery.
    The Annals of thoracic surgery, 2008, Volume: 86, Issue:1

    Topics: Coronary Artery Bypass; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Follow-Up S

2008
Phaeochromocytoma in the Hong Kong Chinese population.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2010, Volume: 16, Issue:4

    Topics: 3-Iodobenzylguanidine; Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Catecholamines; Female; Fol

2010
Pretreatment with phenoxybenzamine attenuates the radial artery's vasoconstrictor response to alpha-adrenergic stimuli.
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 126, Issue:5

    Topics: Adrenergic alpha-Antagonists; Case-Control Studies; Coronary Artery Bypass; Coronary Disease; Female

2003
Pressure distention compared with pharmacologic relaxation in vein grafting upregulates matrix metalloproteinase-2 and -9.
    Journal of vascular surgery, 2005, Volume: 42, Issue:4

    Topics: Animals; Biomarkers; Biopsy, Needle; Blotting, Western; Carotid Stenosis; Dilatation, Pathologic; Di

2005
Phenoxybenzamine selectively and irreversibly inactivates dopaminergic D2 receptors on primary cultured rat lactotrophs.
    Neuroendocrinology, 1992, Volume: 56, Issue:3

    Topics: Animals; Cells, Cultured; Male; Phenoxybenzamine; Pituitary Gland, Anterior; Prolactin; Rats; Rats,

1992
Glucagon and clonidine testing in the diagnosis of pheochromocytoma.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:6 Pt 1

    Topics: Adrenal Gland Neoplasms; Catechols; Clonidine; Drug Therapy, Combination; Glucagon; Humans; Hyperten

1991