isradipine has been researched along with Sensitivity and Specificity in 10 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A meta-analysis was performed to compare the risk of serious adverse events associated with the use of all formulations of isradipine, when used as monotherapy in hypertension, to active drug or placebo controls." | 4.79 | Risk of serious adverse events in hypertensive patients receiving isradipine: a meta-analysis. ( Allen, IE; Arellano, FM; Kumashiro, M; Kupelnick, B; Mohanty, N; Ross, SD, 1997) |
| " This method offered good precision and accuracy and was successfully applied for the pharmacokinetic and bioequivalence studies of 5 mg of sustained-release isradipine in 24 healthy Korean volunteers." | 1.35 | Quantification of isradipine in human plasma using LC-MS/MS for pharmacokinetic and bioequivalence study. ( Jhee, OH; Kang, JS; Kim, SH; Lee, MH; Park, JH; Park, YS; Rhim, SY; Shaw, LM; Yang, SC, 2009) |
| "Treatment with glyburide, pinacidil or hydralazine did not alter L-type calcium channels, assessed by [3H]PN 200 110 binding, in cardiac and brain membranes or small size Ca(2+)-activated K+ channels in brain assessed by [125I]apamin binding." | 1.28 | Regulation of ATP-sensitive K+ channels by chronic glyburide and pinacidil administration. ( Gopalakrishnan, M; Triggle, DJ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, JH | 1 |
| Park, YS | 1 |
| Rhim, SY | 1 |
| Jhee, OH | 1 |
| Kim, SH | 1 |
| Yang, SC | 1 |
| Lee, MH | 1 |
| Shaw, LM | 1 |
| Kang, JS | 1 |
| Aguiar, FA | 1 |
| de Gaitani, CM | 1 |
| Borges, KB | 1 |
| Belal, F | 1 |
| Al-Majed, A | 1 |
| Julkhuf, S | 1 |
| Canda, A | 1 |
| Yu, BH | 1 |
| Sze, PY | 1 |
| Damiani, E | 1 |
| Larsson, L | 1 |
| Margreth, A | 1 |
| Arsac, C | 1 |
| Raymond, C | 1 |
| Martin-Moutot, N | 1 |
| Dargent, B | 1 |
| Couraud, F | 1 |
| Pouget, J | 1 |
| Seagar, M | 1 |
| Bidouil, S | 1 |
| Dubois, J | 1 |
| Hanocq, M | 1 |
| Ross, SD | 1 |
| Kupelnick, B | 1 |
| Kumashiro, M | 1 |
| Arellano, FM | 1 |
| Mohanty, N | 1 |
| Allen, IE | 1 |
| Takamura, K | 1 |
| Kusu, F | 1 |
| Abdel-Wadood, H | 1 |
| El-Rabbat, N | 1 |
| Saleh, G | 1 |
| Refaat, I | 1 |
| Gopalakrishnan, M | 1 |
| Triggle, DJ | 1 |
1 review available for isradipine and Sensitivity and Specificity
| Article | Year |
|---|---|
Risk of serious adverse events in hypertensive patients receiving isradipine: a meta-analysis.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Isradipine; Male; Middle Aged; Randomized Con | 1997 |
9 other studies available for isradipine and Sensitivity and Specificity
| Article | Year |
|---|---|
Quantification of isradipine in human plasma using LC-MS/MS for pharmacokinetic and bioequivalence study.
Topics: Calcium Channel Blockers; Calibration; Chromatography, High Pressure Liquid; Humans; Isradipine; Ref | 2009 |
Capillary electrophoresis method for the determination of isradipine enantiomers: stability studies and pharmaceutical formulation analysis.
Topics: beta-Cyclodextrins; Drug Stability; Electrophoresis, Capillary; Isradipine; Linear Models; Osmolar C | 2011 |
Voltammetric determination of isradipine in dosage forms and spiked human plasma and urine.
Topics: Calcium Channel Blockers; Calibration; Capsules; Humans; Isradipine; Polarography; Reproducibility o | 2003 |
Biochemical characterization of ethanol actions on dihydropyridine-sensitive calcium channels in brain synaptosomes.
Topics: Adenosine Triphosphate; Alcoholism; Animals; Binding Sites; Brain; Calcium Channel Blockers; Calcium | 1995 |
Age-related abnormalities in regulation of the ryanodine receptor in rat fast-twitch muscle.
Topics: Aging; Animals; Antibiotics, Antineoplastic; Binding Sites; Caffeine; Calcium; Calcium Channel Block | 1996 |
Immunoassays fail to detect antibodies against neuronal calcium channels in amyotrophic lateral sclerosis serum.
Topics: Amyotrophic Lateral Sclerosis; Animals; Autoantibodies; Brain; Calcium Channel Blockers; Calcium Cha | 1996 |
Isocratic high-performance liquid chromatographic method for the separation of isradipine and its main metabolites. Application to in vitro metabolization by h3A4/OR cells.
Topics: Calcium Channel Blockers; Cell Line; Chromatography, High Pressure Liquid; Humans; Isradipine; Repro | 1997 |
Redox properties of isradipine and its electrochemical detection in the HPLC determination of the compound in human serum.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Electrochem | 2000 |
Regulation of ATP-sensitive K+ channels by chronic glyburide and pinacidil administration.
Topics: Adenosine Triphosphate; Animals; Apamin; Brain; Calcium; Calcium Channels; Glyburide; Guanidines; He | 1992 |