Assay ID | Title | Year | Journal | Article |
AID328971 | Inhibition of human recombinant SAHH at 1000 uM | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8
| Synthesis of 4'-modified noraristeromycins to clarify the effect of the 4'-hydroxyl groups for inhibitory activity against S-adenosyl-L-homocysteine hydrolase. |
AID199457 | Kinetic constant against bovine liver S-adenosyl-L-homocysteine hydrolase (AdoHcy). | 1992 | Journal of medicinal chemistry, May-15, Volume: 35, Issue:10
| 4'-modified analogues of aristeromycin and neplanocin A: synthesis and inhibitory activity toward S-adenosyl-L-homocysteine hydrolase. |
AID235642 | Selectivity index was evaluated [Selectivity = (CC50 / EC50) against Hepatitis B virus in human hepatoblastoma cell line] | 1998 | Journal of medicinal chemistry, Jun-04, Volume: 41, Issue:12
| Does the anti-hepatitis B virus activity of (+)-5'-noraristeromycin exist in its 4'-epimer and 4'-deoxygenated derivatives? |
AID1152851 | Genotoxicity in Salmonella typhi in presence of liver S9 fraction | 2014 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 24, Issue:12
| Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase. |
AID328969 | Inhibition of Plasmodium falciparum recombinant SAHH at 1000 uM | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8
| Synthesis of 4'-modified noraristeromycins to clarify the effect of the 4'-hydroxyl groups for inhibitory activity against S-adenosyl-L-homocysteine hydrolase. |
AID86873 | Effective concentration against Hepatitis B virus in human hepatoblastoma cell line | 1998 | Journal of medicinal chemistry, Jun-04, Volume: 41, Issue:12
| Does the anti-hepatitis B virus activity of (+)-5'-noraristeromycin exist in its 4'-epimer and 4'-deoxygenated derivatives? |
AID199453 | Inhibitory activity against bovine liver S-adenosyl-L-homocysteine hydrolase (AdoHcy). | 1992 | Journal of medicinal chemistry, May-15, Volume: 35, Issue:10
| 4'-modified analogues of aristeromycin and neplanocin A: synthesis and inhibitory activity toward S-adenosyl-L-homocysteine hydrolase. |
AID233173 | Ratio of kinetic constant to inhibitory activity against bovine liver S-adenosyl-L-homocysteine hydrolase(AdoHcy). | 1992 | Journal of medicinal chemistry, May-15, Volume: 35, Issue:10
| 4'-modified analogues of aristeromycin and neplanocin A: synthesis and inhibitory activity toward S-adenosyl-L-homocysteine hydrolase. |
AID1152852 | Genotoxicity in Salmonella typhi in absence of liver S9 fraction | 2014 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 24, Issue:12
| Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase. |
AID328972 | Selectivity ratio of human recombinant SAHH to Plasmodium falciparum recombinant SAHH | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8
| Synthesis of 4'-modified noraristeromycins to clarify the effect of the 4'-hydroxyl groups for inhibitory activity against S-adenosyl-L-homocysteine hydrolase. |
AID86871 | Cytotoxic concentration against Hepatitis B virus in human hepatoblastoma cell line | 1998 | Journal of medicinal chemistry, Jun-04, Volume: 41, Issue:12
| Does the anti-hepatitis B virus activity of (+)-5'-noraristeromycin exist in its 4'-epimer and 4'-deoxygenated derivatives? |
AID1152850 | Inhibition of AHCY in human SH-SY5Y cells assessed as formation of homocysteine after 48 hrs by HPLC analysis | 2014 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 24, Issue:12
| Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase. |
AID86872 | Effective concentration against Hepatitis B virus in human hepatoblastoma cell line | 1998 | Journal of medicinal chemistry, Jun-04, Volume: 41, Issue:12
| Does the anti-hepatitis B virus activity of (+)-5'-noraristeromycin exist in its 4'-epimer and 4'-deoxygenated derivatives? |
AID1152849 | Inhibition of recombinant human AHCY using SAH as substrate assessed as formation of homocysteine after 10 mins | 2014 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 24, Issue:12
| Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |