Compounds > tiletamine
Page last updated: 2024-09-22

tiletamine

Description

Tiletamine: Proposed anesthetic with possible anticonvulsant and sedative properties. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID26533
CHEMBL ID2110703
CHEBI ID94356
SCHEMBL ID115212
MeSH IDM0021530

Synonyms (48)

Synonym
tiletamine
cyclohexanone, 2-(ethylamino)-2-(2-thienyl)-
BSPBIO_001203
NCGC00179264-01
BPBIO1_001325
AB00514642
PRESTWICK3_001022
2-(ethylamino)-2-(2-thienyl)cyclohexanone
tiletamina [inn-spanish]
tiletaminum [inn-latin]
tiletamine [inn:ban]
einecs 238-031-9
SPBIO_003064
PRESTWICK1_001022
PRESTWICK0_001022
PRESTWICK2_001022
D08596
tiletamine (inn)
14176-49-9
AKOS005066229
2-(ethylamino)-2-thiophen-2-ylcyclohexan-1-one
2-(ethylamino)-2-thiophen-2-yl-1-cyclohexanone
2-(ethylamino)-2-thiophen-2-yl-cyclohexan-1-one
A807808
tiletamina
2yfc543249 ,
unii-2yfc543249
tiletaminum
hsdb 7638
BRD-A30582499-003-01-0
tiletamine [who-dd]
tiletamine [hsdb]
tiletamine [mi]
tiletamine [inn]
SCHEMBL115212
DTXSID5048552
CHEMBL2110703
2-(ethylamino)-2-(2-thienyl)cyclohexanone #
QAXBVGVYDCAVLV-UHFFFAOYSA-N
AC-23715
AB00514642_02
J-524970
CHEBI:94356
FT-0756967
14176-49-9 (free base)
DB11549
Q2083144
NCGC00179264-03

Research Excerpts

Overview

ExcerptReference
"Tiletamine/zolazepam is a dissociative anesthetic combination commonly used in small animals but information is limited in rats. "( Durongphongtorn, S; Jampachaisri, K; Limprasutr, V; Pacharinsak, C; Sharp, P, 2021)
"Tiletamine-zolazepam is a widely used as an alternative chemical immobilization method in non-human primates, with a safe application pathway and necessary relaxation. "( Andrade, JK; Carreiro, ADN; Costa, TSF; de La Salles, AYF; de Menezes, DJA; de Souza, AP; de Souza, JG; Lemos, KKA; Reinaldo, MPOS, 2019)
"Tiletamine is a disassociative anesthetic similar to ketamine and phencyclidine, and zolazepam is a diazepine derivative tranquilizer used to minimize the muscle hypertonicity and seizures associated with tiletamine."( Camporese, T; Cording, CJ; DeLuca, R; Spratt, E, 1999)
"Tiletamine hydrochloride is a lipophilic and potent veterinary anesthetic."( Bohacek, R; ffRench-Mullen, JM; Fisher, RS; Lehmann, J, 1987)

Treatment

ExcerptReference
"Treatment with tiletamine had a slight, but insignificant, effect on CYP-mediated enzyme activities."( Bandiera, SM; Wong, A, 1998)
"Pretreatment with tiletamine did not attenuate the MK-801-induced increases in rat pyriform cortical DA metabolism, a result suggesting that tiletamine is not a partial agonist of the NMDA-uncoupled PCP recognition sites in this region."( Cler, JA; Contreras, PC; Dilworth, VM; Iyengar, S; Mick, SJ; Monahan, JB; Rao, TS; Wood, PL, 1991)

Drug Classes (1)

ClassDescription
aralkylamineAn alkylamine in which the alkyl group is substituted by an aromatic group.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (340)

TimeframeStudies, This Drug (%)All Drugs %
pre-199035 (10.29)18.7374
1990's96 (28.24)18.2507
2000's89 (26.18)29.6817
2010's88 (25.88)24.3611
2020's32 (9.41)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials64 (18.08%)5.53%
Reviews8 (2.26%)6.00%
Case Studies13 (3.67%)4.05%
Observational1 (0.28%)0.25%
Other268 (75.71%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
medetomidine[no description available]medium6115imidazoles
zolazepam[no description available]medium31958
l 659066[no description available]medium22
xylazine[no description available]medium104231,3-thiazine;
methylbenzene;
secondary amino compound		alpha-adrenergic agonist;
analgesic;
emetic;
muscle relaxant;
sedative
ketamine[no description available]medium10821cyclohexanones;
monochlorobenzenes;
secondary amino compound		analgesic;
environmental contaminant;
intravenous anaesthetic;
neurotoxin;
NMDA receptor antagonist;
xenobiotic
methadone[no description available]medium33benzenes;
diarylmethane;
ketone;
tertiary amino compound
isoflurane[no description available]medium195organofluorine compoundinhalation anaesthetic
alphaxalone[no description available]medium32corticosteroid hormone
acepromazine[no description available]medium185aromatic ketone;
methyl ketone;
phenothiazines;
tertiary amino compound		phenothiazine antipsychotic drug
midazolam[no description available]medium141imidazobenzodiazepine;
monofluorobenzenes;
organochlorine compound		anticonvulsant;
antineoplastic agent;
anxiolytic drug;
apoptosis inducer;
central nervous system depressant;
GABAA receptor agonist;
general anaesthetic;
muscle relaxant;
sedative
sufentanil[no description available]medium10anilide;
ether;
piperidines;
thiophenes		anaesthesia adjuvant;
intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic
tramadol[no description available]medium412-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanoladrenergic uptake inhibitor;
antitussive;
capsaicin receptor antagonist;
delta-opioid receptor agonist;
kappa-opioid receptor agonist;
metabolite;
mu-opioid receptor agonist;
muscarinic antagonist;
nicotinic antagonist;
NMDA receptor antagonist;
opioid analgesic;
serotonergic antagonist;
serotonin uptake inhibitor
azaperone[no description available]medium52aminopyridine;
aromatic ketone;
monofluorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
tertiary amino compound		antipsychotic agent;
dopaminergic antagonist
nad[no description available]medium10organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
c-peptide[no description available]medium10
glucagon[no description available]medium10peptide hormone
propofol[no description available]medium93phenolsanticonvulsant;
antiemetic;
intravenous anaesthetic;
radical scavenger;
sedative
glycerol[no description available]medium10alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
dexmedetomidine[no description available]medium128medetomidinealpha-adrenergic agonist;
analgesic;
non-narcotic analgesic;
sedative
haloperidol[no description available]medium10aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
butorphanol[no description available]medium2311morphinane alkaloidantitussive;
kappa-opioid receptor agonist;
mu-opioid receptor agonist;
opioid analgesic
detomidine[no description available]medium174
adenosine monophosphate[no description available]medium11adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
hyaluronoglucosaminidase[no description available]medium20
flunitrazepam[no description available]medium101,4-benzodiazepinone;
C-nitro compound;
monofluorobenzenes		anxiolytic drug;
GABAA receptor agonist;
sedative
hydrogen carbonate[no description available]medium20carbon oxoanioncofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
atipamezole[no description available]medium205
chloral hydrate[no description available]medium10aldehyde hydrate;
ethanediol;
organochlorine compound		general anaesthetic;
mouse metabolite;
sedative;
xenobiotic
nitrous acid[no description available]medium10nitrogen oxoacid
hydrogen sulfide[no description available]medium10gas molecular entity;
hydracid;
mononuclear parent hydride;
sulfur hydride		Escherichia coli metabolite;
genotoxin;
metabolite;
signalling molecule;
toxin;
vasodilator agent
pentobarbital[no description available]medium122barbituratesGABAA receptor agonist
trilostane[no description available]medium1017beta-hydroxy steroid;
3-hydroxy steroid;
androstanoid;
epoxy steroid;
nitrile		abortifacient;
antineoplastic agent;
EC 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitor
dihydrotestosterone[no description available]medium1017beta-hydroxy steroid;
17beta-hydroxyandrostan-3-one;
3-oxo-5alpha-steroid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
corticosterone[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
nalbuphine[no description available]medium11organic heteropentacyclic compoundmu-opioid receptor antagonist;
opioid analgesic
diazepam[no description available]medium821,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic
romifidine[no description available]medium41
nicotine[no description available]medium103-(1-methylpyrrolidin-2-yl)pyridineanxiolytic drug;
biomarker;
immunomodulator;
mitogen;
neurotoxin;
nicotinic acetylcholine receptor agonist;
peripheral nervous system drug;
phytogenic insecticide;
plant metabolite;
psychotropic drug;
teratogenic agent;
xenobiotic
caffeine[no description available]medium10purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic
morphine[no description available]medium32morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic
sorbitol[no description available]medium10glucitolcathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent
arginine[no description available]medium10arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
arginine methyl ester[no description available]medium10alpha-amino acid ester
atropine[no description available]medium52
urethane[no description available]medium20carbamate esterfungal metabolite;
mutagen
sevoflurane[no description available]medium10ether;
organofluorine compound		central nervous system depressant;
inhalation anaesthetic;
platelet aggregation inhibitor
fentanyl[no description available]medium81anilide;
monocarboxylic acid amide;
piperidines		adjuvant;
anaesthesia adjuvant;
anaesthetic;
intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic
sulfobromophthalein[no description available]medium102-benzofurans;
organobromine compound;
organosulfonic acid;
phenols		dye
fluorodeoxyglucose f18[no description available]medium202-deoxy-2-((18)F)fluoro-D-glucose;
2-deoxy-2-fluoro-aldehydo-D-glucose
naloxone[no description available]medium11morphinane alkaloid;
organic heteropentacyclic compound;
tertiary alcohol		antidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist
flumazenil[no description available]medium82ethyl ester;
imidazobenzodiazepine;
organofluorine compound		antidote to benzodiazepine poisoning;
GABA antagonist
lactic acid[no description available]medium212-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
a3080[no description available]medium11
yohimbine[no description available]medium121methyl 17-hydroxy-20xi-yohimban-16-carboxylatealpha-adrenergic antagonist;
dopamine receptor D2 antagonist;
serotonergic antagonist
citalopram[no description available]medium102-benzofurans;
cyclic ether;
nitrile;
organofluorine compound;
tertiary amino compound
halothane[no description available]medium70haloalkane;
organobromine compound;
organochlorine compound;
organofluorine compound		inhalation anaesthetic
carfentanil[no description available]medium40methyl ester;
piperidines;
tertiary amino compound;
tertiary carboxamide		mu-opioid receptor agonist;
opioid analgesic;
tranquilizing drug
naltrexone[no description available]medium30cyclopropanes;
morphinane-like compound;
organic heteropentacyclic compound		antidote to opioid poisoning;
central nervous system depressant;
environmental contaminant;
mu-opioid receptor antagonist;
xenobiotic
tolazoline[no description available]medium10imidazolesalpha-adrenergic antagonist;
antihypertensive agent;
vasodilator agent
malondialdehyde[no description available]medium10dialdehydebiomarker
glycopyrrolate[no description available]medium22organic bromide salt;
quaternary ammonium salt
angiotensin ii[no description available]medium10amino acid zwitterion;
angiotensin II		human metabolite
buprenorphine[no description available]medium11morphinane alkaloiddelta-opioid receptor antagonist;
kappa-opioid receptor antagonist;
mu-opioid receptor agonist;
opioid analgesic
thiopental[no description available]medium32barbituratesanticonvulsant;
drug allergen;
environmental contaminant;
intravenous anaesthetic;
sedative;
xenobiotic
piperidines[no description available]medium10
phencyclidine[no description available]medium80benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
adenosine[no description available]medium10adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
dioxadrol[no description available]medium10diarylmethane
histamine[no description available]medium10aralkylamino compound;
imidazoles		human metabolite;
mouse metabolite;
neurotransmitter
promazine[no description available]medium30phenothiazines;
tertiary amine		antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
serotonergic antagonist
doxapram[no description available]medium10morpholines;
pyrrolidin-2-ones		central nervous system stimulant
4-aminopyridine[no description available]medium10aminopyridine;
aromatic amine		avicide;
orphan drug;
potassium channel blocker
droperidol[no description available]medium20aromatic ketone;
benzimidazoles;
organofluorine compound		anaesthesia adjuvant;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic
oxymorphone[no description available]medium10morphinane alkaloid
guaifenesin[no description available]medium51methoxybenzenes
thiamylal[no description available]medium10barbiturates;
organosulfur compound		sedative
metomidate[no description available]medium11imidazoles
etomidate[no description available]medium21ethyl ester;
imidazoles		intravenous anaesthetic;
sedative
methoxyflurane[no description available]medium20ether;
organochlorine compound;
organofluorine compound		hepatotoxic agent;
inhalation anaesthetic;
nephrotoxic agent;
non-narcotic analgesic
lidocaine[no description available]medium10benzenes;
monocarboxylic acid amide;
tertiary amino compound		anti-arrhythmia drug;
drug allergen;
environmental contaminant;
local anaesthetic;
xenobiotic
phenobarbital[no description available]medium10barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
squalene[no description available]medium10triterpenehuman metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
phenytoin[no description available]medium10imidazolidine-2,4-dioneanticonvulsant;
drug allergen;
sodium channel blocker;
teratogenic agent
naltrexazone[no description available]medium10
sarmazenil[no description available]medium20
urea[no description available]medium10isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
etorphine[no description available]medium20
diprenorphine[no description available]medium10morphinane alkaloid
succinylcholine[no description available]medium10quaternary ammonium ion;
succinate ester		drug allergen;
muscle relaxant;
neuromuscular agent
methohexital[no description available]medium10acetylenic compound;
barbiturates		drug allergen;
intravenous anaesthetic
pilocarpine[no description available]medium10pilocarpineantiglaucoma drug
gallamine triethiodide[no description available]medium10
chloramphenicol[no description available]medium20C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor
fluorobenzenes[no description available]medium10monofluorobenzenesNMR chemical shift reference compound
dimethylphenylpiperazinium iodide[no description available]medium10N-arylpiperazine;
organic iodide salt;
piperazinium salt;
quaternary ammonium salt		nicotinic acetylcholine receptor agonist
tyramine[no description available]medium10monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter
isoproterenol[no description available]medium10catechols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent
2-amino-7-phosphonoheptanoic acid[no description available]medium20
baclofen[no description available]medium10amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid;
monochlorobenzenes;
primary amino compound		central nervous system depressant;
GABA agonist;
muscle relaxant
2-amino-5-phosphonovalerate[no description available]medium20non-proteinogenic alpha-amino acidNMDA receptor antagonist
bicuculline[no description available]medium10benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines		agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin
gentamicin[no description available]medium10
n-methylaspartate[no description available]medium30amino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound		neurotransmitter agent
dizocilpine maleate[no description available]medium30maleate salt;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
cyclic gmp[no description available]medium103',5'-cyclic purine nucleotide;
guanyl ribonucleotide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
aspartic acid[no description available]medium20aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
quinolinic acid[no description available]medium10pyridinedicarboxylic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite;
NMDA receptor agonist
3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid[no description available]medium10
homocysteine[no description available]medium10amino acid zwitterion;
homocysteine;
serine family amino acid		fundamental metabolite;
mouse metabolite
choline[no description available]medium10cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
homocysteic acid[no description available]medium10homocysteic acidNMDA receptor agonist
tetrodotoxin[no description available]medium10azatetracycloalkane;
oxatetracycloalkane;
quinazoline alkaloid		animal metabolite;
bacterial metabolite;
marine metabolite;
neurotoxin;
voltage-gated sodium channel blocker
thiophenes[no description available]medium10mancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound		non-polar solvent
borneo[no description available]medium10organofluorine acaricide
foxes[no description available]medium40
tebuconazole[no description available]medium10monochlorobenzenes;
tertiary alcohol;
triazoles
s,n,n'-tripropylthiocarbamate[no description available]medium20tertiary amine
apnea[no description available]medium20purine nucleoside
cetylpyridinium chloride anhydrous[no description available]medium10chloride salt;
organic chloride salt		antiseptic drug;
surfactant
fomesafen[no description available]medium40aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-sulfonylcarboxamide;
organofluorine compound;
phenols		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
exudates[no description available]medium10
2-propanol[no description available]medium10secondary alcohol;
secondary fatty alcohol		protic solvent
n-methylhistamine[no description available]low00aralkylamine
phenethylamine[no description available]low00alkaloid;
aralkylamine;
phenylethylamine		Escherichia coli metabolite;
human metabolite;
mouse metabolite
n-(3-(aminomethyl)benzyl)acetamidine[no description available]low00aralkylamine;
carboxamidine;
primary amino compound		angiogenesis inhibitor;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
geroprotector
5-methylfurtrethonium[no description available]low00aralkylamine
ranitidine[no description available]low00aralkylamine
benzylamine[no description available]low00aralkylamine;
primary amine		allergen;
EC 3.5.5.1 (nitrilase) inhibitor;
plant metabolite
furtrethonium[no description available]low00aralkylamine
2-morpholino-1-phenyl-1-ethanol[no description available]low00aralkylamine
n-phenylethanolamine[no description available]low00aralkylamine
trihexyphenidyl hydrochloride[no description available]low00aralkylamine
fepradinol[no description available]low00aralkylamine
perisoxal[no description available]low00aralkylamine
tiemonium iodide[no description available]low00aralkylamine
N-methyl-N-(3-pyridylmethyl)amine[no description available]low00aralkylamine
6-amino-2-methyl-8-phenyl-1,6,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile[no description available]low00aralkylamine
5-[(4-chlorophenyl)methylamino]-6-methyl-2H-1,2,4-triazin-3-one[no description available]low00aralkylamine
N-(4,6-dimethyl-2-pyrimidinyl)-1,3-bis(phenylmethyl)-2,4-dihydro-1,3,5-triazin-6-amine[no description available]low00aralkylamine
1-ethyl-5-(phenylmethyl)-1,3,5-triazinane-2-thione[no description available]low00aralkylamine
N4-(3-chlorophenyl)-6-methyl-N2-(phenylmethyl)pyrimidine-2,4-diamine[no description available]low00aralkylamine
2-[[3-[(2-hydroxyphenyl)methyl]-1,3-diazinan-1-yl]methyl]phenol[no description available]low00aralkylamine
N-(phenylmethyl)-4-(3-pyridinyl)-2-thiazolamine[no description available]low00aralkylamine
[3-(phenylmethyl)-2,4-dihydro-1H-1,3,5-triazin-6-yl]cyanamide[no description available]low00aralkylamine
N-[(4-chlorophenyl)methyl]-6-(3,5-dimethyl-1-pyrazolyl)-1,2,4,5-tetrazin-3-amine[no description available]low00aralkylamine
5-[(4-methyl-1-piperidinyl)methyl]-1-[4-(1-pyrrolyl)-1,2,5-oxadiazol-3-yl]-4-triazolecarboxylic acid ethyl ester[no description available]low00aralkylamine
3-amino-5-[3-(methylamino)propyl]-1H-pyrazole-4-carbonitrile[no description available]low00aralkylamine
3-(3-bromoanilino)-1-(5-methyl-2-furanyl)-1-propanone[no description available]low00aralkylamine
4-phenyl-N-(pyridin-4-ylmethyl)-2-butanamine[no description available]low00aralkylamine
5-(4-piperidinyl)-1,2-dihydropyrazol-3-one[no description available]low00aralkylamine
N-[(4-chlorophenyl)methyl]-4-(2-furanyl)-6-(trifluoromethyl)-2-pyrimidinamine[no description available]low00aralkylamine
4-[[anilino-(4-methylphenyl)methyl]-propoxyphosphoryl]-N,N-dimethylaniline[no description available]low00aralkylamine
(2S)-1-(1H-imidazol-5-yl)-2-propanamine[no description available]low00aralkylamine
4-[3-(1H-imidazol-5-yl)propyl]piperidine[no description available]low00aralkylamine
(2R)-3-[[(2S)-1-cyclohexyl-3-(methylamino)propan-2-yl]amino]-2-[(1-phenylcyclopropyl)methylamino]-1-propanol[no description available]low00aralkylamine
ConditionIndicatedRelationship StrengthStudiesTrials
Abdominal Cryptorchidism0medium11
Absence Seizure0low20
Absence Seizures0low20
Ache0medium33
Acid Aspiration Syndrome0low10
Acidosis0medium11
Action Tremor0low20
Acute Brain Injuries0low10
Aerophagy0low10
Aggression0low10
Aging0medium21
Agitation, Psychomotor0low10
Air Swallowing0low10
Akathisia0low10
Alkalosis0low10
Anaphylactic Reaction0low10
Anaphylactoid Reaction0low10
Anaphylactoid Shock0low10
Anaphylaxis0low10
Anemia, Fanconi0low10
Anesthesia0medium8716
Angel Dust Abuse0low10
Anoxemia0medium31
Anoxia0medium31
Anterior Cervical Pain0low10
Anterior Neck Pain0low10
Ape Diseases0low10
Apnea0low20
Apoplexy0low10
Arrhythmia0low30
Arrhythmia, Sinoatrial0low10
Arrhythmia, Sinus0low10
Arrhythmias, Cardiac0low30
Arrythmia0low30
Aspiration Pneumonia0low10
Ataxia0low10
Ataxia, Appendicular0low10
Ataxia, Limb0low10
Ataxia, Motor0low10
Ataxia, Sensory0low10
Ataxia, Truncal0low10
Ataxy0low10
Atonic Absence Seizure0low20
Atonic Absence Seizures0low20
Atonic Seizure0low20
Atonic Seizures0low20
Atopic Hypersensitivity0low10
Aura0low10
Autotomy Human0low10
Awakening Epilepsy0low10
Bilateral Cryptorchidism0medium11
Bilateral Headache0low10
Bites0low10
Bites and Stings0low10
Black Death0low10
Black Plague0low10
Blood Pressure, High0medium21
Body Weight0low50
Bradyarrhythmia0medium22
Bradyarrhythmias0medium22
Bradycardia0medium22
Brain Injuries0low10
Brain Injuries, Acute0low10
Brain Injuries, Focal0low10
Brain Ischemia0low10
Brain Lacerations0low10
Bubonic Plague0low10
Budd-Chiari Syndrome0low10
Canine Diseases0low50
Cardiac Arrhythmia0low30
Cardiac Arrhythmias0low30
Cardiac Dysrhythmia0low30
Cardiac Failure0low10
Cardiovascular Diseases0low20
Cat Diseases0low10
Cephalalgia0low10
Cephalgia0low10
Cephalodynia0low10
Cerebral Ischemia0low10
Cerebral Stroke0low10
Cerebrovascular Accident0low10
Cerebrovascular Accident, Acute0low10
Cerebrovascular Apoplexy0low10
Cerebrovascular Stroke0low10
Cervical Pain0low10
Cervicalgia0low10
Cervicodynia0low10
Chemical Dependence0low40
Chest Injuries0low10
Chiari's Syndrome0low10
Clonic Seizure0low20
Clonic Seizures0low20
Coarse Tremor0low20
Communicable Diseases0low10
Complex Partial Seizure0low20
Complex Partial Seizures0low20
Complication, Postoperative0low10
Congestive Heart Failure0low10
Continuous Tremor0low20
Convulsion0low20
Convulsion, Non-Epileptic0low20
Convulsions0low20
Convulsive Seizure0low20
Convulsive Seizures0low20
Coordination Impairment0low10
Coronary Disease0low10
Coronary Heart Disease0low10
Cranial Pain0low10
Cryptorchidism0medium11
Cryptorchidism, Unilateral Or Bilateral0medium11
Cryptorchism0medium11
CVA (Cerebrovascular Accident)0low10
Darkness Tremor0low20
Deficiency, Oxygen0medium31
Delirium0low10
Delirium of Mixed Origin0low10
Disease Models, Animal0low30
Dog Diseases0low50
Drug Abuse0low40
Drug Abuse, Intravenous0low10
Drug Abuse, Parenteral0low10
Drug Addiction0low40
Drug Dependence0low40
Drug Habituation0low40
Drug Use Disorders0low40
Dyscoordination0low10
Dyssynergia0low10
Encephalopathy, Ischemic0low10
Epilepsy0low10
Epilepsy, Cryptogenic0low10
Epileptic Seizure0low20
Epileptic Seizures0low20
Equine Diseases0medium11
Excitement, Psychomotor0low10
Experimental Lung Inflammation0low10
Extravascular Hemolysis0low10
Fanconi Anemia0low10
Fanconi Hypoplastic Anemia0low10
Fanconi Pancytopenia0low10
Fanconi Panmyelopathy0low10
Fanconi's Anemia0low10
Feline Diseases0low10
Fever0medium31
Fine Tremor0low20
Focal Brain Injuries0low10
Fractures, Closed0low10
Fractures, Occult0low10
Gastric Acid Aspiration Syndrome0low10
Gastric Dilatation0low10
Gastric Dilation0low10
Generalized Absence Seizure0low20
Generalized Absence Seizures0low20
Generalized Headache0low10
Generalized Tonic-Clonic Seizures0low20
Glaucoma0low10
Haemolysis0low10
Head Pain0low10
Headache0low10
Heart Decompensation0low10
Heart Failure0low10
Heart Failure, Congestive0low10
Heart Failure, Left-Sided0low10
Heart Failure, Right-Sided0low10
Hemicrania0low10
Hemolysis0low10
Hepatic Vein Thrombosis0low10
Hepatic Venous Outflow Obstruction0low10
Hepatitis, Viral, Animal0low10
Horse Diseases0medium11
Hypercapnia0low10
Hyperglycemia0low20
Hyperglycemia, Postprandial0low20
Hypersensitivity, Atopic0low10
Hypersensitivity, Immediate0low10
Hypersensitivity, Type I0low10
Hypertension0medium21
Hypothermia0low20
Hypothermia, Accidental0low20
Hypoxemia0medium31
Hypoxia0medium31
IgE-Mediated Hypersensitivity0low10
Incoordination0low10
Infections, Respiratory0low10
Infections, Respiratory Tract0low10
Infections, Upper Respiratory0low10
Infections, Upper Respiratory Tract0low10
Infectious Diseases0low10
Inguinal Cryptorchidism0medium11
Injuries, Acute Brain0low10
Injuries, Brain0low10
Injuries, Chest0low10
Injuries, Thoracic0low10
Intention Tremor0low20
Intermittent Tremor0low20
Intraocular Pressure0medium61
Intravascular Hemolysis0low10
Intravenous Drug Abuse0low10
Involuntary Quiver0low20
Ischemia, Cerebral0low10
Ischemic Encephalopathy0low10
Jacksonian Seizure0low20
Kidney Diseases0low10
Lack of Coordination0low10
Laryngeal Diseases0low10
Laryngeal Perichondritis0low10
Larynx Diseases0low10
Left-Sided Heart Failure0low10
Lobar Pneumonia0low10
Lung Inflammation0low10
Massive Tremor0low20
Mendelson Syndrome0low10
Mendelson's Syndrome0low10
Meningeal Plague0low10
Metabolic Acidosis0medium11
Muscle Disorders0low10
Muscle Relaxation0medium145
Muscular Diseases0low10
Myocardial Failure0low10
Myoclonic Seizure0low20
Myoclonic Seizures0low20
Myopathic Conditions0low10
Myopathies0low10
Neck Ache0low10
Neck Pain0low10
Neckache0low10
Nephrosis0low10
Non-Epileptic Seizure0low20
Non-Epileptic Seizures0low20
Nonepileptic Seizure0low20
Nonepileptic Seizures0low20
Ocular Headache0low10
Organic Mental Disorders, Substance-Induced0low40
Orthostatic Headache0low10
Ovine Diseases0low10
Oxygen Deficiency0medium31
Pain0medium33
Pain, Burning0medium33
Pain, Crushing0medium33
Pain, Migratory0medium33
Pain, Radiating0medium33
Pain, Splitting0medium33
Partial Seizure0low20
Partial Seizures0low20
Passive Tremor0low20
PCP Abuse0low10
Periorbital Headache0low10
Persistent Tremor0low20
Petit Mal Convulsion0low20
Phencyclidine Abuse0low10
Phencyclidine-Related Disorders0low10
Pill Rolling Tremor0low20
Plague0low10
Pneumonia0low10
Pneumonia, Aspiration0low10
Pneumonia, Lobar0low10
Pneumonic Plague0low10
Pneumonitis0low10
Pongidae Diseases0low10
Posterior Cervical Pain0low10
Posterior Neck Pain0low10
Postoperative Complications0low10
Postprandial Hyperglycemia0low20
Pregnancy0low50
Prescription Drug Abuse0low40
Psychomotor Agitation0low10
Psychomotor Hyperactivity0low10
Psychomotor Restlessness0low10
Psychoses, Drug0low10
Psychoses, Substance-Induced0low10
Psychoses, Toxic0low10
Pulmonary Inflammation0low10
Pulmonic Plague0low10
Pyrexia0medium31
Radius Fractures0low10
Respiratory Infections0low10
Respiratory Tract Infections0low10
Rest Tremor0low20
Resting Tremor0low20
Restlessness0low10
Retro-Ocular Headache0low10
Right-Sided Heart Failure0low10
Rodent Diseases0low10
Saturnine Tremor0low20
Seizure0low20
Seizure Disorder0low10
Seizures0low20
Seizures, Auditory0low20
Seizures, Clonic0low20
Seizures, Convulsive0low20
Seizures, Epileptic0low20
Seizures, Focal0low20
Seizures, Generalized0low20
Seizures, Gustatory0low20
Seizures, Motor0low20
Seizures, Olfactory0low20
Seizures, Sensory0low20
Seizures, Somatosensory0low20
Seizures, Tonic0low20
Seizures, Tonic-Clonic0low20
Seizures, Vertiginous0low20
Seizures, Vestibular0low20
Seizures, Visual0low20
Self Mutilating Behavior0low10
Self Mutilation0low10
Senile Tremor0low20
Sensitivity and Specificity0low20
Septicemic Plague0low10
Sharp Headache0low10
Sheep Diseases0low10
Shock, Anaphylactic0low10
Single Seizure0low20
Sinoatrial Arrhythmia0low10
Sinus Arrhythmia0low10
Static Tremor0low20
Stings0low10
Stings and Bites0low10
Stomach Dilatation0low10
Stomach Dilation0low10
Stroke0low10
Stroke, Acute0low10
Subacute Delirium0low10
Substance Abuse0low40
Substance Abuse, Intravenous0low10
Substance Addiction0low40
Substance Dependence0low40
Substance Use0low40
Substance Use Disorders0low40
Substance-Induced Psychoses0low10
Substance-Related Disorders0low40
Suffering, Physical0medium33
Surgical Incision0low10
Surgical Wound0low10
Swine Diseases0low10
Testes, Undescended0medium11
Testis, Undescended0medium11
Thoracic Injuries0low10
Throbbing Headache0low10
Tonic Clonic Seizure0low20
Tonic Seizure0low20
Tonic Seizures0low20
Tonic-Clonic Seizure0low20
Tonic-Clonic Seizures0low20
Toxic Psychoses0low10
Tremor0low20
Tremor, Limb0low20
Tremor, Muscle0low20
Tremor, Neonatal0low20
Tremor, Nerve0low20
Tremor, Perioral0low20
Tremor, Rubral0low10
Tremor, Semirhythmic0low20
Type I Hypersensitivity0low10
Ulna Fractures0low10
Undescended Testis0medium11
Unilateral Cryptorchidism0medium11
Unilateral Headache0low10
Upper Respiratory Infections0low10
Upper Respiratory Tract Infection0low10
Upper Respiratory Tract Infections0low10
Uremia0low10
Vascular Accident, Brain0low10
Ventricular Fibrillation0low20
Vertex Headache0low10
Viral Hepatitis, Animal0low10
Wounds, Gunshot0low10
Yersinia pestis Infection0low10

Research Highlights

Safety/Toxicity (2)

ArticleYear
Optimization of intraperitoneal injection anesthesia in mice: drugs, dosages, adverse effects, and anesthesia depth.
Comparative medicine, Volume: 51, Issue: 5		2001
Nephrotoxicity of tiletamine in New Zealand white rabbits.
Laboratory animal science, Volume: 42, Issue: 3		1992
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (5)

ArticleYear
Comparison of tiletamine and zolazepam pharmacokinetics in tigers (Panthera tigris) and leopards (Panthera pardus): do species differences account for adverse effects in tigers?
Veterinary journal (London, England : 1997), Volume: 201, Issue: 3		2014
Pharmacokinetic study in pigs and in vitro metabolic characterization in pig- and human-liver microsomes reveal marked differences in disposition and metabolism of tiletamine and zolazepam (Telazol).
Xenobiotica; the fate of foreign compounds in biological systems, Volume: 44, Issue: 4		2014
Biliary clearance of bromosulfophthalein in anesthetized and freely moving conscious rat.
Biopharmaceutics & drug disposition, Volume: 30, Issue: 2		2009
Pharmacokinetics and tissue residues of Telazol in free-ranging polar bears.
Journal of wildlife diseases, Volume: 36, Issue: 4		2000
Steady-state minute volume determination by body-only plethysmography in juvenile rhesus monkeys.
Laboratory animal science, Volume: 46, Issue: 5		1996
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (1)

ArticleYear
Validation of an HPLC assay for determination of Telazol in pregnant pigs: application to placental transfer study.
The Journal of veterinary medical science, Apr-20, Volume: 79, Issue: 4		2017
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (61)

ArticleYear
EVALUATION OF A COMBINATION OF TILETAMINE-ZOLAZEPAM, MEDETOMIDINE, AND AZAPERONE WITH NASAL OXYGEN SUPPLEMENTATION FOR THE IMMOBILIZATION OF CAPTIVE CHACOAN PECCARIES (CATAGONUS WAGNERI) IN THE CHACO REGION OF PARAGUAY.
Journal of wildlife diseases, 04-01, Volume: 59, Issue: 2		2023
Comparison of Alfaxalone-Midazolam, Tiletamine-Zolazepam, and KetamineAcepromazine Anesthesia during Plethysmography in Cynomolgus Macaques (
Comparative medicine, 08-01, Volume: 72, Issue: 4		2022
Determination of the effective dosage of tiletamine-zolazepam-ketamine-xylazine, with or without methadone, in dogs.
Veterinary anaesthesia and analgesia, Volume: 49, Issue: 3		2022
Comparison of anesthetic effects of tiletamine-zolazepam-medetomidine or ketamine-medetomidine in captive Amur leopard cats (Prionailurus bengalensis euptailurus).
Veterinary anaesthesia and analgesia, Volume: 48, Issue: 3		2021
Immobilization of Asiatic Black Bears ( Ursus thibetanus ) with Medetomidine-Zolazepam-Tiletamine in South Korea.
Journal of wildlife diseases, Volume: 53, Issue: 3		2017
Validation of an HPLC assay for determination of Telazol in pregnant pigs: application to placental transfer study.
The Journal of veterinary medical science, Apr-20, Volume: 79, Issue: 4		2017
Influence of Ambient Temperature and Confinement on the Chemical Immobilization of Fallow Deer ( Dama dama ).
Journal of wildlife diseases, Volume: 53, Issue: 2		2017
Chemical Restraint of Free-ranging South American Coatis ( Nasua nasua ) with a Combination of Tiletamine and Zolazepam.
Journal of wildlife diseases, Volume: 53, Issue: 1		2017
Propofol pretreatment induced place preference and self-administration of the tiletamine-zolazepam combination: implication on drug of abuse substitution.
The American journal of drug and alcohol abuse, Volume: 40, Issue: 4		2014
Romifidine and low doses of tiletamine-zolazepam in dogs.
Veterinary anaesthesia and analgesia, Volume: 40, Issue: 6		2013
Repetitive TASER X26 discharge resulted in adverse physiologic events with a dose-response relationship related to the duration of discharge in anesthetized swine model.
Journal of forensic sciences, Volume: 58, Issue: 1		2013
Field anesthesia of wild ring-tailed lemurs (Lemur catta) using tiletamine-zolazepam, medetomidine, and butorphanol.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, Volume: 42, Issue: 1		2011
Use of hyaluronidase to improve chemical immobilization of free-ranging polar bears (Ursus maritimus).
Journal of wildlife diseases, Volume: 46, Issue: 1		2010
Reversible immobilization of asiatic black bear (Ursus thibetanus) with detomidine-tiletamine-zolazepam and atipamezole.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, Volume: 39, Issue: 4		2008
Tiletamine-zolazepam-xylazine immobilization of fishers (Martes pennanti).
Journal of wildlife diseases, Volume: 43, Issue: 2		2007
Immobilization of Japanese black bears (Ursus thibetanus japonicus) with tiletamine hydrochloride and zolazepam hydrochloride.
The Journal of veterinary medical science, Volume: 69, Issue: 4		2007
Immobilization of free-ranging maned wolf (Chrysocyon brachyurus) with tiletamine and zolazepam in central Brazil.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, Volume: 37, Issue: 1		2006
Tiletamine-zolazepam-xylazine immobilization of American marten (Martes americana).
Journal of wildlife diseases, Volume: 41, Issue: 3		2005
[Immobilization of cattle and bison with a combination of xylazine, zolazepam-tiletamine and ketamine].
Tijdschrift voor diergeneeskunde, May-01, Volume: 130, Issue: 9		2005
Chemical immobilization of crested porcupines with tiletamine HCl and zolazepam HCl (Zoletil) under field conditions.
Journal of wildlife diseases, Volume: 39, Issue: 3		2003
Anesthesia of polar bears using xylazine-zolazepam-tiletamine or zolazepam-tiletamine.
Journal of wildlife diseases, Volume: 39, Issue: 3		2003
Tiletamine-zolazepam, ketamine, and xylazine anesthesia of captive cheetah (Acinonyx jubatus).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, Volume: 33, Issue: 4		2002
Response of wild subantarctic fur seal (Arctocephalus tropicalis) females to ketamine and tiletamine-zolazepam anesthesia.
Journal of wildlife diseases, Volume: 38, Issue: 4		2002
Use of the anesthetic combination of tiletamine, zolazepam, ketamine, and xylazine for neutering feral cats.
Journal of the American Veterinary Medical Association, May-15, Volume: 220, Issue: 10		2002
Optimization of intraperitoneal injection anesthesia in mice: drugs, dosages, adverse effects, and anesthesia depth.
Comparative medicine, Volume: 51, Issue: 5		2001
A novel anaesthetic regimen for surgical procedures in guineapigs.
Laboratory animals, Volume: 35, Issue: 3		2001
Anesthesia in female white-tailed deer using Telazol and xylazine.
Journal of wildlife diseases, Volume: 36, Issue: 4		2000
A Zoletil-Rompun mixture as an alternative to the use of opioids for immobilization of feral red deer.
Journal of wildlife diseases, Volume: 36, Issue: 4		2000
Pharmacokinetics and tissue residues of Telazol in free-ranging polar bears.
Journal of wildlife diseases, Volume: 36, Issue: 4		2000
Immobilization of wild ocelots with tiletamine and zolazepam in southern Texas.
Journal of wildlife diseases, Volume: 36, Issue: 3		2000
Field anesthesia of free-living mountain gorillas (Gorilla gorilla beringei) from the Virunga Volcano region, Central Africa.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, Volume: 31, Issue: 1		2000
Comparison of five regimens for oral administration of medication to induce sedation in dogs prior to euthanasia.
Journal of the American Veterinary Medical Association, Jul-15, Volume: 213, Issue: 2		1998
Induction of hepatic cytochrome P450 2B and P450 3A isozymes in rats by zolazepam, a constituent of Telazol.
Biochemical pharmacology, Jan-15, Volume: 55, Issue: 2		1998
Immobilization of collared peccaries (Tayassu tajacu) and feral hogs (Sus scrofa) with Telazol and xylazine.
Journal of wildlife diseases, Volume: 33, Issue: 1		1997
Evaluation of anaesthetic regimens in guineapigs.
Laboratory animals, Volume: 30, Issue: 3		1996
Immobilization of Rocky Mountain elk with Telazol and xylazine hydrochloride, and antagonism by yohimbine hydrochloride.
Journal of wildlife diseases, Volume: 31, Issue: 2		1995
Immobilization of guanacos by use of tiletamine/zolazepam.
Journal of the American Veterinary Medical Association, Feb-01, Volume: 208, Issue: 3		1996
Use of tiletamine and zolazepam to immobilize captive Iberian wolves (Canis lupus).
Journal of wildlife diseases, Volume: 30, Issue: 1		1994
Field application of Telazol (tiletamine hydrochloride and zolazepam hydrochloride) to immobilize wild red howler monkeys (Alouatta seniculus) in Venezuela.
Journal of wildlife diseases, Volume: 30, Issue: 3		1994
Evaluation of use of tiletamine/zolazepam for anesthesia of bullfrogs and leopard frogs.
Journal of the American Veterinary Medical Association, Jul-01, Volume: 207, Issue: 1		1995
Evaluation of a combination of tiletamine and zolazepam as an anesthetic for laboratory rodents.
Laboratory animal science, Volume: 33, Issue: 5		1983
A new anesthetic agent for use in the gerbil.
Laboratory animal science, Volume: 39, Issue: 4		1989
Use of Telazol to immobilize female northern sea lions (Eumetopias jubatus) in Alaska.
Journal of wildlife diseases, Volume: 25, Issue: 3		1989
Xylazine and tiletamine-zolazepam anesthesia in horses.
American journal of veterinary research, Volume: 50, Issue: 5		1989
Evaluation of a combination of tiletamine and zolazepam as an anesthetic for ferrets.
Laboratory animal science, Volume: 39, Issue: 3		1989
Immobilization of polar bears (Ursus maritimus) with Telazol in the Canadian Arctic.
Journal of wildlife diseases, Volume: 25, Issue: 2		1989
Dissociative anaesthesia in free-ranging male koalas and selected marsupials in captivity.
Australian veterinary journal, Volume: 67, Issue: 12		1990
Immobilization of wild dogs (Lycaon pictus) with a tiletamine hydrochloride/zolazepam hydrochloride combination and subsequent evaluation of selected blood chemistry parameters.
Journal of wildlife diseases, Volume: 27, Issue: 2		1991
[Anesthesia in dogs with the combination preparation Tilest 500].
Tierarztliche Praxis, Volume: 19, Issue: 1		1991
An evaluation of medetomidine/ketamine and other drug combinations for anaesthesia in cats.
The Veterinary record, Jan-12, Volume: 128, Issue: 2		1991
Cardiopulmonary effects of a tiletamine-zolazepam combination in sheep.
American journal of veterinary research, Volume: 52, Issue: 9		1991
Contrasting neurochemical interactions of tiletamine, a potent phencyclidine (PCP) receptor ligand, with the N-methyl-D-aspartate-coupled and -uncoupled PCP recognition sites.
Journal of neurochemistry, Volume: 56, Issue: 3		1991
A preliminary investigation into the immobilising potential of a tiletamine/zolazepam mixture, metomidate, a metomidate and azaperone combination and medetomidine in ostriches (Struthio camelus).
Journal of the South African Veterinary Association, Volume: 62, Issue: 3		1991
Immobilization of giant Chacoan peccaries (Catagonus wagneri) with a tiletamine hydrochloride/zolazepam hydrochloride combination.
Journal of wildlife diseases, Volume: 28, Issue: 3		1992
Influence of various anesthetic drugs on the intraocular pressure of cats.
Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, Apr-14, Volume: 199, Issue: 2		1976
Visual evoked response (VER) changes during maturation in the Weddell seal.
Developmental psychobiology, Volume: 9, Issue: 5		1976
Tiletamine and zolazepam for immobilization of wild lions and leopards.
Journal of the American Veterinary Medical Association, Nov-01, Volume: 171, Issue: 9		1977
Influence of cataleptoid anaesthetic agents on the intraocular pressure in monkeys (Macaca fascicularis).
Acta ophthalmologica, Volume: 54, Issue: 4		1976
CI-744 anesthesia for ophthalmological examination and surgery in monkeys.
Investigative ophthalmology, Volume: 14, Issue: 10		1975
Comparison of anesthetic agents in the sea otter.
Journal of the American Veterinary Medical Association, Nov-01, Volume: 173, Issue: 9		1978
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Interactions (10)

ArticleYear
Comparison of the Cardiovascular Effects of Two Medetomidine Doses Combined with Tiletamine-Zolazepam for the Immobilization of Red Deer Hinds (Cervus elaphus).
Journal of wildlife diseases, 01-01, Volume: 58, Issue: 1		2022
Use of nalbuphine as a substitute for butorphanol in combination with dexmedetomidine and tiletamine/zolazepam: a randomized non-inferiority trial.
Journal of feline medicine and surgery, Volume: 22, Issue: 2		2020
A comparison of low dose tiletamine-zolazepam or acepromazine combined with methadone for pre-anaesthetic medication in cats.
Veterinary anaesthesia and analgesia, Volume: 41, Issue: 6		2014
Physiologic and antinociceptive effects following intramuscular administration of xylazine hydrochloride in combination with tiletamine-zolazepam in llamas.
American journal of veterinary research, Volume: 74, Issue: 4		2013
Comparison of the anesthetic effects of oral transmucosal versus injectable medetomidine in combination with tiletamine-zolazepam for immobilization of chimpanzees (Pan troglodytes).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, Volume: 41, Issue: 1		2010
Comparison of anaesthetic and cardiorespiratory effects of xylazine or medetomidine in combination with tiletamine/zolazepam in pigs.
The Veterinary record, Aug-14, Volume: 167, Issue: 7		2010
Comparison of four drug combinations for total intravenous anesthesia of horses undergoing surgical removal of an abdominal testis.
Journal of the American Veterinary Medical Association, Sep-15, Volume: 217, Issue: 6		2000
Anesthetic effects of tiletamine-zolazepam, alone or in combination with butorphanol, in goats.
Journal of the American Veterinary Medical Association, Sep-01, Volume: 211, Issue: 5		1997
Ketamine, Telazol, xylazine and detomidine. A comparative anesthetic drug combinations study in ponies.
Acta veterinaria Scandinavica, Volume: 33, Issue: 2		1992
The acid-base status of lions, Panthera leo, immobilized with four drug combinations.
Journal of wildlife diseases, Volume: 14, Issue: 1		1978
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]