Page last updated: 2024-11-10

3,7,12,24-tetrahydroxycholestanoic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID3080578
CHEBI ID48742
MeSH IDM0083306

Synonyms (14)

Synonym
3,7,12,24-tetrahydroxycholestanoic acid
tthca
cholestan-26-oic acid, 3,7,12,24-tetrahydroxy-, (3alpha,5beta,7alpha,12alpha)- (van)
1061-64-9
LMST04030067
3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oic acid
varanic acid
CHEBI:48742
3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoic acid
3alpha,7alpha,12alpha,24xi-tetrahydroxy-5beta-cholestan-26-oic acid
(3a,5b,7a,12a)-3,7,12,24-tetrahydroxy-cholestan-26-oic acid
Q27121366
(6r)-3-hydroxy-2-methyl-6-((3r,5s,7r,8r,9s,10s,12s,13r,14s,17r)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1h-cyclopenta[a]phenanthren-17-yl)heptanoic acid
DTXSID901318051
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
bile acid metaboliteMetabolites of bile acids, four-ringed steroid acids formed along the cholesterol degradation pathway.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (5)

ClassDescription
3alpha-hydroxy steroidA 3-hydroxy steroid in which the 3-hydroxy substituent is in the alpha-position.
7alpha-hydroxy steroidA 7-hydroxy steroid in which the hydroxy group at position 7 has an alpha-configuration.
12alpha-hydroxy steroid
24-hydroxy steroid
hydroxy monocarboxylic acidAny monocarboxylic acid which also contains a separate (alcoholic or phenolic) hydroxy substituent.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (54.55)18.7374
1990's4 (36.36)18.2507
2000's0 (0.00)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.77

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.77 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.25 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.77)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (9.09%)4.05%
Observational0 (0.00%)0.25%
Other10 (90.91%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]