Page last updated: 2024-12-07
bis(2-propylheptyl)phthalate
Description
Bis(2-propylheptyl) phthalate (BPHP) is a phthalate ester commonly used as a plasticizer in a variety of materials, including PVC, polyvinyl chloride. Its synthesis involves the reaction of phthalic anhydride with 2-propyl-1-heptanol, a type of alcohol. BPHP, like other phthalates, has been studied for its potential endocrine disrupting effects, specifically its ability to interfere with the hormonal system. This concern arises due to its potential to mimic or block hormones, potentially causing health issues. Consequently, its presence in consumer products and its potential environmental impact have led to research efforts focusing on its toxicity, environmental fate, and bioaccumulation. The study of BPHP aims to understand its potential hazards to human health and the environment. While BPHP is generally considered less toxic than other phthalates like DEHP, research continues to assess its safety and potential environmental effects.'
bis(2-propylheptyl)phthalate: a plasticizer with endocrine disrupting activity; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 92344 |
| SCHEMBL ID | 434343 |
| MeSH ID | M000602511 |
Synonyms (25)
| Synonym |
|---|
| 53306-54-0 |
| 1, bis(2-propylheptyl) ester |
| nsc-17071 |
| bis-(2-propylheptyl) phthalate |
| nsc17071 |
| bis(2-propylheptyl) phthalate |
| FT-0663385 |
| bis(2-propylheptyl) benzene-1,2-dicarboxylate |
| einecs 258-469-4 |
| 1,2-benzenedicarboxylic acid, bis(2-propylheptyl) ester |
| ec 258-469-4 |
| 1,2-benzenedicarboxylic acid, 1,2-bis(2-propylheptyl) ester |
| nsc 17071 |
| SCHEMBL434343 |
| DTXSID5052173 |
| AKOS028108536 |
| di(2-propylheptyl) phthalate |
| di(2-propylheptyl)phthalate |
| di-(2-propylheptyl) phthalate |
| bis(2-propylheptyl)phthalate |
| phthalic acid, bis-2-propylheptyl ester |
| MTYUOIVEVPTXFX-UHFFFAOYSA-N |
| phthalic acid, bis-2-propylheptyl ester 100 microg/ml in acetonitrile |
| di-(2-propyl heptyl) phthalate |
| F71197 |
Research Excerpts
Bioavailability
Dosage Studied
Research
Studies (14)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 12 (85.71) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 23.78
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 23.78 (24.57) | | Research Supply Index | 2.71 (2.92) | | Research Growth Index | 5.91 (4.65) | | Search Engine Demand Index | 21.17 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 2 (14.29%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 12 (85.71%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |