methotrexate has been researched along with Sensitivity and Specificity in 202 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.50) | 18.7374 |
| 1990's | 45 (22.28) | 18.2507 |
| 2000's | 89 (44.06) | 29.6817 |
| 2010's | 62 (30.69) | 24.3611 |
| 2020's | 5 (2.48) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Abdullah, Z; Bashir, S; Hussain, HR; Khan, DH; Khan, MH; Mahmood, A; Rashid, SA; Sarfraz, M; Shahzadi, I | 1 |
| Aletaha, D; Allaart, CF; Combe, B; Fautrel, B; Saevarsdottir, S; Smolen, JS; Van Vollenhoven, R; Vanier, A; Vastesaeger, N; Verschueren, P; Visser, K | 1 |
| Du, SP; Gan, L; Liu, XY; Zhang, J; Zhang, Y | 1 |
| Allan, C; Keating, P; O'Donnell, J; Spellerberg, M; van Voorthuizen, M | 1 |
| Cheng, R; Huang, X; Jiang, Z; Wu, W; Zhang, L | 1 |
| Hua, K; Wang, W; Xie, M; Zhang, X | 1 |
| Becerra-Alvarado, IN; Bonilla-Lara, D; Gamez-Nava, JI; Gonzalez-Lopez, L; Gonzalez-Ponce, F; Murillo-Vazquez, JD; Perez-Guerrero, EE; Ponce-Guarneros, JM; Rodriguez-Jimenez, NA; Saldaña-Cruz, AM; Vazquez-Villegas, ML; Vera-Navarrete, EY; Zuñiga-Mora, JA | 1 |
| Chambost, H; Devictor, B; Fabresse, N; Lacarelle, B; Michel, G; Pissier, C; Solas, C | 1 |
| de Roock, S; Swart, JF; van Dijkhuizen, EHP; Wulffraat, NM | 1 |
| Chorilli, M; Oliveira, AG; Scarpa, MV; Zuben, ESV | 1 |
| Cekmez, Y; Göçmen, A; Sanlιkan, F; Türkmen, SB | 1 |
| Cui, Y; Du, Y; Lin, S; Mei, S; Ren, X; Shi, X; Yu, K; Zeng, C; Zhao, Z | 1 |
| Beyan, E; Budak, A; Hamdi İnan, A; Kanmaz, AGK | 1 |
| Cloos, J; de Jonge, R; Hebing, RCF; Heydari, P; Jansen, G; Lems, WF; Lin, M; Muller, IB; Nurmohamed, MT; Struys, EA; van der Laken, C | 1 |
| van de Laar, MA; Vonkeman, HE | 1 |
| Ganti, V; Nagar, S; Walker, EA | 1 |
| Berglin, E; Dahlqvist, SR | 1 |
| Byun, BH; Cho, WH; Choi, CW; Jeon, DG; Koh, JS; Kong, CB; Lee, SY; Lim, I; Lim, SM; Song, WS | 1 |
| Boissinot, M; Burska, A; Conaghan, PG; El Jawhari, J; El-Sherbiny, Y; Emery, P; Goëb, V; Harrison, S; Hensor, E; Parmar, R; Ponchel, F; Vital, EM | 1 |
| Bari, SF; Khan, A; Lawson, T | 1 |
| Ikeda, K; Iwamoto, T; Kawashima, H; Nakagomi, D; Nakajima, H; Okubo, A; Sanayama, Y; Takahashi, K; Yamagata, M | 1 |
| Becker, I; Horneff, G | 1 |
| Cheng, MM; Shih, WC; Tan, X; Yang, J | 1 |
| Boechat, NL; Oliveira, SK; Ribeiro, SB; Sant'Anna, CC; Sztajnbok, DC; Sztajnbok, F | 1 |
| Almog, B; Bibi, G; Cohen, A; Levin, I; Tsafrir, Z | 1 |
| Atkinson, M; Gupta, S; Mcgee, T | 1 |
| Chen, JR; Feng, JJ; Huang, H; Lu, YC; Wang, AJ; Wang, W | 1 |
| Altay, M; Cırık, DA; Gelisen, O; Yıldırım, A | 1 |
| Akkurt, O; Akkuş, M; Altay, M; Gelisen, O; Karadeniz, RS; Tasci, Y | 1 |
| Bulatović Ćalasan, M; de Jonge, R; de Rotte, MC; Kamphuis, S; Pluijm, SM; van Dijkhuizen, EH; Vastert, SJ; Wulffraat, NM | 1 |
| Ceccarelli, F; Finucci, A; Iagnocco, A; Iorgoveanu, V; Perricone, C; Valesini, G | 1 |
| Bosello, SL; Di Gregorio, F; Di Molfetta, V; Ferraccioli, G; Gremese, E; Mirone, L; Peluso, G; Pirronti, T | 1 |
| Bang, SY; Jeong, WK; Kim, JY; Kim, MY; Kim, TY; Kim, Y; Lee, HS; Sohn, JH | 1 |
| Boyer, O; Cosette, P; Fardellone, P; Hardouin, J; Jarnier, F; Lequerré, T; Loët, XL; Marcelli, C; Obry, A; Philippe, P; Vittecoq, O | 1 |
| Alves, C; Barendregt, PJ; de Sonnaville, PB; Gerards, AH; Grillet, BA; Hazes, JM; Luime, JJ; van der Ven, M; van Schaeybroeck, B; van Zeben, D | 1 |
| Hong, YH; Kim, HJ; Kim, MJ; Lee, CK | 1 |
| Banno, S; Imai, H; Iwagaitsu, S; Maeda, S; Naniwa, T; Niimi, A; Nobata, H; Tamechika, S | 1 |
| Imura, S; Murata, M; Shiozawa, K; Shiozawa, S; Tsumiyama, K; Yamane, T; Yoshihara, R | 1 |
| Hattori, N; Hirata, K; Kikuchi, Y; Kobayashi, K; Manabe, O; Oyama-Manabe, N; Tamaki, N; Toyonaga, T; Watanabe, S | 1 |
| Abu Zaid, M; Antin, JH; Choi, SW; Cutler, C; Logan, BR; Paczesny, S; Wu, C; Wu, J; Yu, J | 1 |
| Machado de Campos, A; Pinheiro Cruz, A; Sartori, T; Seigi Murakami, F | 1 |
| Lee, YH; Lim, KT; Moon, MH; Park, SH; Yang, JH | 1 |
| Michalak, M; Nowak-Markwitz, E; Olejnik, M; Spaczynski, M | 1 |
| Hirakawa, K | 1 |
| Haid, A; Konstantiniuk, P; Kugler, F; Pöstlberger, S; Reitsamer, R; Roka, S; Tausch, C | 1 |
| Fujimoto, T; Hamada, K; Hashimoto, N; Hatazawa, J; Inoue, A; Myoui, A; Tomita, Y; Yoshikawa, H | 1 |
| Berbenetz, NM; Giaever, G; Nislow, C; Yan, Z | 1 |
| Aoshima, K; Kadowaki, T; Oda, Y; Tanaka, M; Tanaka, S; Uehara, T; Yokoi, A | 1 |
| Al-Refai, EA; Amjad D, AN; Khassawneh, MY; Sadiq, MF | 1 |
| Hashiguchi, M; Inoue, S; Kawai, S; Mochizuki, M | 1 |
| Butler, RN; Howarth, GS; Lymn, KA; Tooley, KL | 1 |
| Abramson, L; Arkachaisri, T; Benseler, S; Cabral, DA; Campillo, S; Chira, P; Dewitt, EM; Eberhard, A; Hashkes, PJ; Hersh, AO; Higgins, G; Huber, AM; Kim, S; Kingsbury, DJ; Klein-Gitelman, M; Levy, DM; Li, SC; Lovell, DJ; Mason, T; McCurdy, D; Muscal, E; Nassi, L; O'Neil, KM; Reiff, A; Schikler, K; Singer, NG; Stevens, A; Uribe, AG; Wahezi, D; Woodward, A; Zeft, AS | 1 |
| Becker, ML; Leeder, JS; Stobaugh, JF; van Haandel, L; Williams, TD | 1 |
| Avril, N; Avril-Sassen, S; Dose-Schwarz, J; Jänicke, F; Lebeau, A; Mahner, S; Schwaiger, M; Tiling, R; Untch, M; Weber, C | 1 |
| Yano, S; Yoshikawa, K | 1 |
| Allaart, CF; de Vries-Bouwstra, JK; Dijkmans, BA; Gerards, AH; Goekoop-Ruiterman, YP; Güler-Yüksel, M; Huizinga, TW; Klarenbeek, NB; Lems, WF; Ronday, HK; van der Kooij, SM | 1 |
| Bombardier, C; Faulkner, A; Feldman, B; Katchamart, W; Tomlinson, G | 1 |
| Huizinga, TW; Knevel, R; van der Helm-van Mil, AH; van der Linden, MP | 1 |
| Feldman, BM; Goia, C; Luthra, S; Manlhiot, C; Schmeling, H; Schneider, R; Stephens, S; Stringer, E | 1 |
| Armbrust, W; Bulatović, M; Egberts, TC; Heijstek, MW; Hoppenreijs, EP; Kamphuis, S; Kuis, W; Rademaker, CM; Sinnema, G; van Dijkhuizen, EH; Verkaaik, M; Wulffraat, NM | 1 |
| Bergman, MJ; Furer, V; Keystone, E; Luijtens, K; Pincus, T; Yazici, Y | 1 |
| Altshuler, A; Amir, P; Halperin, R; Maymon, R; Sadeh-Mefpechkin, D; Vaknin, Z | 1 |
| de Jonge, R; den Boer, E; Lindemans, J; Luider, TM; Mathot, RA; Meesters, RJ; van Klaveren, RJ | 1 |
| Barbero-Villares, A; Daudén, E; Gisbert, JP; Gonzalez-Alvaro, I; Mendoza, J; Moreno-Otero, R; Trapero-Marugan, M | 1 |
| de Jonge, R; den Boer, E; Lindemans, J; Luider, TM; Meesters, RJ | 1 |
| Derunes, C; Fang, S; LaBarre, MJ; Lollo, CP | 1 |
| Bracciolini, G; Consolaro, A; Davì, S; Magni-Manzoni, S; Malattia, C; Martini, A; Pederzoli, S; Pistorio, A; Ravelli, A; Ruperto, N | 1 |
| Choy, EH; Hassell, A; Ibrahim, F; Kiely, PD; Ma, MH; Scott, DL; Walker, D; Walsh, DA; Williams, R; Young, A | 1 |
| Ikeda, R; Kono, N; Nakashima, K; Sonemoto, E; Ueki, Y; Wada, M | 1 |
| André, C; Chosidow, O; Hue, S; Ingen-Housz-Oro, S; Le Saché-de Peufeilhoux, L; Ortonne, N; Roujeau, JC; Sbidian, E; Valeyrie-Allanore, L; Wolkenstein, P | 1 |
| de Heij, T; de Jong, DJ; de Vries, HS; Peters, WH; Roelofs, HM; te Morsche, RH | 1 |
| Chen, Z; Hu, Y; Jiang, Y; Tu, S; Wang, Y; Xia, Y | 1 |
| Felea, I; Rednic, S; Tamas, MM | 1 |
| Chen, J; Chen, X; Huang, M; Mo, X; Ren, B; Wang, X; Wen, Y; Xu, C | 1 |
| Ahmad, T; Jena, GB; Khan, S; Parekh, CV; Shekh, K; Vikram, A; Yadav, L | 1 |
| de Jonge, R; den Boer, E; Hazes, JM; Heil, SG; Luider, TM; Meesters, RJ; van Zelst, BD | 1 |
| Levasseur, SD; White, VA; Wittenberg, LA | 1 |
| Ikeda, K; Iwamoto, T; Nakagomi, D; Nakajima, H; Okubo, A; Sanayama, Y; Suzuki, K; Takabayashi, K; Takahashi, K; Takatori, H; Yamagata, M | 1 |
| Combe, B; Knevel, R; Lukas, C; Rincheval, N; van der Heijde, D; van der Helm-van Mil, AH | 1 |
| Durán Merás, I; Espinosa Mansilla, A; Rodríguez Gómez, MJ; Salinas López, F | 1 |
| Leśniewski-Kmak, K; Szczylik, C; Zieliński, KW | 1 |
| Minoia, C; Ronchi, A; Sottani, C; Turci, R | 1 |
| Choi, HK; Kim, DK; Kim, MY; Lee, SK; Lee, WK; Park, YB; Song, J | 1 |
| Becker, A; Bode, U; Jaehde, U; Scheuch, E | 1 |
| Fleischmann, RM | 1 |
| Bode-Böger, SM; Tröger, U | 1 |
| Bares, R; Bartusek, G; Dittmann, H; Dohmen, BM; Kehlbach, R; Pritzkow, M; Sarbia, M | 1 |
| Bangsgaard, N; Lund, CO; Nilas, L; Ottesen, B | 1 |
| Boers, M; Boonen, A; Christgau, S; Garnero, P; Geusens, P; Landewé, R; Van Der Heijde, D; Van Der Linden, S; Verhoeven, A | 1 |
| Aschele, C; Bandelloni, R; Barni, S; Cascinu, S; Catalano, V; Debernardis, D; Drudi, G; Gallo, L; Giordani, P; Lonardi, S; Maley, F; Monfardini, S; Turci, D | 1 |
| Annino, L; Casorelli, I; Chiusolo, P; Laurenti, L; Leone, G; Mele, L; Reddiconto, G; Sica, S; Sorà, F | 1 |
| Arakawa, H; Maeda, M; Suzuki, Y | 1 |
| Hirakawa, T; Kinukawa, N; Nakano, H; Shigematsu, T; Sonoda, T; Yahata, H | 1 |
| Istok, R; Rovensky, J; Stancíková, M; Svík, K | 1 |
| Dervieux, T; Marcelletti, J; Orentas Lein, D; Pischel, K; Richerson, R; Smith, K; Walsh, M | 1 |
| Chiou, SS; Kou, HS; Kuo, CY; Wu, DC; Wu, HL; Wu, SM | 1 |
| Aboul-Enein, HY; Bokretsion, RG; Stefan, RI; van Staden, JF | 1 |
| Anderson, JJ; Bolognese, JA; Felson, DT | 1 |
| Ahmed, I; el-Gaafary, M; el-Miedany, Y; Youssef, S | 1 |
| Bret, G; Kellenberger, E; Müller, P; Paul, N; Rognan, D | 1 |
| Eilola, K; Kola, H; Niemelä, M; Perämäki, P | 1 |
| Aarden, LA; de Groot, ER; de Lathouder, S; Dijkmans, BA; Gerards, AH; Valkhof, MG | 1 |
| Althoff, EA; Carter, BT; Cornish, VW; de Felipe, KS | 1 |
| Mahmood, U; Müller-Ladner, U; Tung, CH; Weissleder, R; Wunder, A | 1 |
| Adèr, HJ; Bibo, J; Boers, M; Boonen, A; Korthals-de Bos, I; Van Der Linden, S; Van Tulder, M; Verhoeven, AC | 1 |
| Andrisano, V; Bertucci, C; Cavrini, V; El-Hady, DA; El-Maali, NA; Gotti, R | 1 |
| Butler, RN; Davidson, GP; Howarth, GS; Pelton, NS; Tivey, DR | 1 |
| Bunescu, A; Egberg, N; Lenkei, R; Levin, K; Seideman, P | 1 |
| Ellingsen, T; Hornung, N; Poulsen, JH; Stengaard-Pedersen, K | 1 |
| Avery, G; Cabral, DA; Green, J; Malleson, PN; Morishita, K; Ortiz-Alvarez, O; Petty, RE; Tucker, LB | 1 |
| Albertioni, F; Fotoohi, K; Peterson, C; Skärby, T; Söderhäll, S | 1 |
| Cecchin, E; Toffoli, G | 1 |
| Barbieri, A; Sabatini, L; Tosi, M; Violante, FS | 1 |
| Klareskog, L; Lindblad, S; van Vollenhoven, RF; Weiss, RJ; Wick, MC | 1 |
| Gómez, MJ; Mansilla, AE; Peñalvo, GC; Rodríguez Flores, J | 1 |
| Andersson, J; Bergh, J; Carlsson, G; Gustavsson, B; Holmberg, L; Inganäs, M; Klaar, S; Larsson, L; Nilsson, J; Ohd, J; Rudenstam, CM | 1 |
| Berzas Nevado, JJ; Durán Merás, I; Rodríguez Flores, J; Rodríguez Gómez, MJ | 1 |
| Dardzinski, BJ; Graham, TB; Laor, T | 1 |
| Biber, D; Heins, S; Horneff, G; Schmeling, H | 1 |
| Batioglu, S; Gocmen, M; Kahyaoglu, S; Sut, N; Turgay, I | 1 |
| Avci, A; Cetin, R; Devrim, E; Durak, I; Ergüder, BI; Kiliçoğlu, B | 1 |
| Höök-Nikanne, J; Kärkkäinen, P; Niemelä, S; Nieminen, U | 1 |
| Barentsz, JO; Peters, M; Schrier, BP; Witjes, JA | 1 |
| Arai, K; Endo, N; Fujisawa, J; Hanyu, T; Kondo, N; Murai, T; Nakazono, K; Sugitani, H | 1 |
| Abdelmalek, E; Abulafia, O; Gabbur, N; Hellmann, M; Phillip, P; Sherer, DM | 1 |
| Ali, M; Chen, TS; Crues, JV; Troum, OM | 1 |
| Ellingsen, T; Hansen, IB; Hornung, N; Lottenburger, T; Poulsen, JH; Stengaard-Pedersen, K | 1 |
| Drummond, DC; Kirpotin, DB; Marks, JD; Nielsen, UB; Pickering, EM | 1 |
| Dietemann, JL; Koob, M | 1 |
| Brünner, N; Christensen, IJ; Foekens, JA; Holten-Andersen, MN; Look, MP; Meijer-van Gelder, ME; Mouridsen, HT; Schrohl, AS | 1 |
| Boudawara, T; Daoud, J; Frikha, M; Kallel, F; Khanfir, A; Meziou, M; Mnif, J; Trabelsi, K | 1 |
| Belinsky, MG; Gallo, JM; Guo, P; Kruh, GD; Liu, L; Wang, X | 1 |
| Agostini, A; Blanc, B; Blanc, K; Capelle, M; Romain, F; Ronda, I | 1 |
| Dias, EM; Fatenejad, S; Landewé, R; Lukas, C; van der Heijde, D | 1 |
| Chou, PP; Mendu, DR; Soldin, SJ | 1 |
| Guchelaar, HJ; Huizinga, TW; Wessels, JA | 1 |
| Bergman, MJ; Hines, P; Maclean, R; Pincus, T; Raghupathi, K; Yazici, Y | 1 |
| Furukawa, S; Handa, H; Inouye, S; Kabe, Y; Kuramori, C; Nakamura, M; Sakamoto, S; Sawa, C; Sawada, J; Suzuki, M; Yamaguchi, Y | 1 |
| Maclean, R; Massarotti, E; Oster, G; Shadick, N; Sofrygin, O; Vera-Llonch, M; Westhovens, R; Wolfe, F; Yuan, Y | 1 |
| Healy, PJ; Helliwell, PS | 1 |
| Cabanillas, F; Cortes, JE; Kurzrock, R; Seymour, JF; Talpaz, M | 1 |
| De Luca, LM; Jones, CS; Ross, SA | 1 |
| Danek, GM; Mangiarotti, MA; Tamaro, G; Tamaro, P; Zanazzo, GA | 1 |
| Meenan, RF; Prashker, MJ | 1 |
| Bergquist, SR; Felson, DT; Freedberg, KA; Prashker, MJ | 1 |
| Fernandez, H; Fournet, P; Frydman, R; Lelaidier, C | 1 |
| Baggiolini, M; Dewald, B; Loetscher, P; Seitz, M | 1 |
| Albro, JE; Arias, JM; Christian, PE; Datz, FL; Greenberg, HE; Morton, KA; Patch, GG; Valdivia, S | 1 |
| Bader, H; Eisenberger, F; Guhl, L; Jipp, P; Nunnensiek, C; Rassweiler, J; Ruether, U; Schmidt, A; Stilz, S | 1 |
| Adler, DD; Cody, RL; Helvie, MA; Joynt, LK; Merajver, SD; Pierce, LJ | 1 |
| Alric, C; Cociglio, M; Hillaire-Buys, D | 1 |
| Cush, J; Heudebert, G; Jain, R; Kavanaugh, A | 1 |
| Aboleneen, H; Backes, D; Simpson, J | 1 |
| Brégeon, C; Coste, J; Guillemin, F; Pouchot, J; Sany, J | 2 |
| Blotner, SD; Furst, DE; Kremer, JM; Weinblatt, ME | 1 |
| Goodyear, N; Kahan, BD; Murthy, JN; Napoli, KL; Soldin, SJ | 1 |
| Becagli, P; Messori, A; Tendi, E; Trippoli, S | 1 |
| Boffa, MJ; Chalmers, RJ; Haboubi, NY; Mitchell, DM; Rowan, B; Shomaf, M; Smith, A; Warnes, TW | 1 |
| Bregeon, C; Coste, J; Ghézail, M; Guillemin, F; Pouchot, J; Sany, J | 1 |
| Dibenedetto, SP; Lo Nigro, L; Mayer, SP; Rovera, G; Schilirò, G | 1 |
| Dees, EC; Shulman, LN; Smith, BL; Souba, WW | 1 |
| Breucq, C; Goes, E; Osteaux, M | 1 |
| Barentsz, JO; Berger-Hartog, O; Hulsbergen-van der Kaa, C; Kondacki, H; Oosterhof, GO; Ruijs, SH; VanderLaak, JA; Witjes, JA | 1 |
| Fradet, Y | 1 |
| Airoldi, M; Albanese, F; Di Costanzo, G; Fazio, M; Gariboldi, A; Mastromatteo, V; Pecchio, F | 1 |
| Chen, S; Garber, A; Shaheen, A | 1 |
| Boers, M; Buchbinder, R; Saurez-Almazor, M; Shea, B; Tugwell, P; Wells, G; Westhovens, R | 1 |
| Jansen, G; Kaspers, GJ; Mauritz, R; Noordhuis, P; Peters, GJ; Pieters, R; Rots, MG; van Zantwijk, CH; Veerman, AJ | 1 |
| Adamson, PC; Balis, FM; Widemann, BC | 1 |
| McCrudden, EA; Tett, SE | 1 |
| Boers, M; Boonen, A; Edmonds, J; Lassere, M; Saudan, A; van der Heijde, D; Verhoeven, AC | 1 |
| Bizri, AR; Kahwaji, S; Khalil, A; Medawar, W; Seoud, M; Shamseddine, A; Taher, A | 1 |
| Habbal, Z; Ibrahim, K; Kahwaji, S; Khalil, A; Medawar, W; Seoud, M; Shamseddine, A | 1 |
| Colombi, A; Floridia, L; Pietropaolo, AM; Rubino, FM; Tavazzani, M | 1 |
| Algara, P; Díaz, MA; Madero, L; Martínez, P; Tutor-Ureta, O | 1 |
| Breedveld, F; Emery, P; Feldmann, M; Furst, D; Harriman, G; Kalden, J; Lipsky, P; Maini, R; Smolen, J; St Clair, EW; Weisman, M | 1 |
| Loos, WJ; Nooter, K; Sparreboom, A; Stoter, G; Verweij, J | 1 |
| Fiorentino, ML; Minoia, C; Sottani, C; Turci, R | 1 |
| Handa, T; Kai, S; Kazami, A; Koizumi, K; Maruyama, M; Takemoto, N; Yamao, T | 1 |
| Choi, HK; Kuntz, KM; Seeger, JD | 2 |
| Bañares, A; Fernández-Gutiérrez, B; Hernández-García, C; Jover, JA; Morado, IC; Vargas, E | 1 |
| Bemelman, WA; Griffioen, G; Hermans, J; Ivenski, M; van Hogezand, RA; Veenendaal, RA | 1 |
| Fujimura, A; Kasahara, K; Kobayashi, E; Nagai, H; Sugimoto, K; To, H; Uchida, H; Xiu, D | 1 |
| Bessho, F; Hanada, R; Hoshi, Y; Ikuta, K; Ishimoto, K; Kaneko, T; Kinoshita, A; Koike, K; Maeda, M; Manabe, A; Nakazawa, S; Ohara, A; Okawa, H; Okimoto, Y; Saito, T; Sato, T; Sugita, K; Toyoda, Y; Tsuchida, M; Tsunematsu, Y | 1 |
| Curtin, NJ; Errington, J; Lu, X; Lunec, J; Newell, DR | 1 |
| Deng, Y; Unger, SE; Wu, JT; Zeng, H | 1 |
| Bertino, JR; Cordon-Cardo, C; Elisseyeff, Y; Faircloth, G; Jhanwar, S; Jimeno, J; Li, WW; Takahashi, N | 1 |
| Boers, M; Boonen, A; Dijkmans, BA; Jacobs, P; Landewé, RB; Markusse, HM; Peeters, AJ; van de Laar, MA; van Denderen, JC; van der Heijde, DM; van der Linden, S; Verhoeven, AC; Westedt, ML; Westhovens, R | 1 |
| Kleeberg, UR | 1 |
| Khokhar, NZ; Lam, AF; Rusch, VW; Sirotnak, FM | 1 |
| Ansoborlo, S; Babin-Boilletot, A; Baruchel, A; Pacquement, H; Patte, C; Plouvier, E; Sakiroglu, C | 1 |
| Durán Merás, I; Espinosa-Mansilla, A; Ferreyra, C; Pedano, L; Zamora Madera, A | 1 |
| Bingham, EA; Burrows, D; Callender, ME; Delvin, PB; Ferguson, WR; Laird, JD; McHenry, PM; O'Hara, MD | 1 |
| Bub, P; Eisenberger, F; Rüther, U; Schmidt, A | 1 |
| Carpentier, P; de Pauw, M; Jacqmin, D; Pavone-Macaluso, M; Roberts, JT; Splinter, TA; Sylvester, R | 1 |
| Hawley, DJ; Wolfe, F | 1 |
| McIvor, RS; Thompson, K; Vinh, DB | 1 |
| Cedard, L; Risquez, F; Zorn, JR | 1 |
| Couret, M; Cuchacovich, M; Gatica, H; Peray, P; Sany, J | 1 |
9 review(s) available for methotrexate and Sensitivity and Specificity
| Article | Year |
|---|---|
The new European League Against Rheumatism/American College of Rheumatology diagnostic criteria for rheumatoid arthritis: how are they performing?
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Methotrexate; Sensitivity and Specificity | 2013 |
C reactive protein may not be reliable as a marker of severe bacterial infection in patients receiving tocilizumab.
Topics: Aged; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Infectious; Arthritis, Rheumatoid; Biomarkers; C-Reactive Protein; Humans; Knee Joint; Male; Methotrexate; Prednisolone; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Staphylococcal Infections; Sulfasalazine; Treatment Outcome | 2013 |
Examining the efficacy of biologic therapy: are there real differences?
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Etanercept; Female; Follow-Up Studies; Humans; Immunoglobulin G; Infliximab; Interleukin 1 Receptor Antagonist Protein; Male; Methotrexate; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Sensitivity and Specificity; Sialoglycoproteins; Treatment Outcome | 2002 |
Uridine diphosphoglucuronosyl transferase and methylenetetrahydrofolate reductase polymorphisms as genomic predictors of toxicity and response to irinotecan-, antifolate- and fluoropyrimidine-based chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Fluorouracil; Glucuronosyltransferase; Humans; Irinotecan; Male; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Pharmacogenetics; Polymorphism, Genetic; Sensitivity and Specificity; Toxicogenetics | 2004 |
[Liver damage in methotrexate-treated patients. When liver biopsy is necessary in the follow-up?].
Topics: Arthritis, Rheumatoid; Biopsy, Needle; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Female; Follow-Up Studies; Humans; Immunohistochemistry; Inflammatory Bowel Diseases; Liver; Liver Diseases; Liver Function Tests; Male; Methotrexate; Psoriasis; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index | 2005 |
Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis.
Topics: Adenosine; Animals; Apoptosis; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Proliferation; Clinical Trials as Topic; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Folic Acid; Humans; Immunity, Cellular; Immunosuppression Therapy; Male; Methotrexate; Reactive Oxygen Species; Sensitivity and Specificity; Treatment Outcome | 2008 |
Ultrasound studies in ectopic pregnancies.
Topics: Adnexa Uteri; Fallopian Tubes; Female; Humans; Immunosuppressive Agents; Laparoscopy; Methotrexate; Microsurgery; Minimally Invasive Surgical Procedures; Pregnancy; Pregnancy Outcome; Pregnancy, Ectopic; Risk Factors; Rupture, Spontaneous; Sensitivity and Specificity; Survival Rate; Ultrasonography, Doppler, Color; Ultrasonography, Prenatal; Uterus; Vagina | 1998 |
Phenotypic characterization of bladder cancer.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Transitional Cell; Cisplatin; Disease Progression; Doxorubicin; Female; Humans; Immunotherapy; Lymphatic Metastasis; Male; Mass Screening; Methotrexate; Microscopy, Electron; Neoplasm Staging; Phenotype; Prognosis; Sensitivity and Specificity; Urinary Bladder Neoplasms; Vinblastine | 1998 |
Ectopic pregnancy.
Topics: Causality; Chorionic Gonadotropin; Female; Humans; Hysterosalpingography; Laparoscopy; Methotrexate; Pregnancy; Pregnancy, Ectopic; Renin; Salpingostomy; Sensitivity and Specificity; Ultrasonography | 1992 |
34 trial(s) available for methotrexate and Sensitivity and Specificity
| Article | Year |
|---|---|
Combination of 18F-FDG PET/CT and diffusion-weighted MR imaging as a predictor of histologic response to neoadjuvant chemotherapy: preliminary results in osteosarcoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Diffusion Magnetic Resonance Imaging; Doxorubicin; Female; Fluorodeoxyglucose F18; Humans; Male; Methotrexate; Middle Aged; Multimodal Imaging; Neoadjuvant Therapy; Osteosarcoma; Pilot Projects; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Subtraction Technique; Tomography, X-Ray Computed; Treatment Outcome; Young Adult | 2013 |
Correlation of radiographic progression with the cumulative activity of synovitis estimated by power Doppler ultrasound in rheumatoid arthritis: difference between patients treated with methotrexate and those treated with biological agents.
Topics: Adalimumab; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Arthrography; Disease Progression; Etanercept; Female; Humans; Immunoglobulin G; Infliximab; Male; Methotrexate; Middle Aged; Observer Variation; Prospective Studies; Receptors, Tumor Necrosis Factor; Sensitivity and Specificity; Synovitis; Tumor Necrosis Factor-alpha; Ultrasonography, Doppler | 2013 |
Assessment of Substantial Liver Fibrosis by Real-time Shear Wave Elastography in Methotrexate-Treated Patients With Rheumatoid Arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Causality; Chemical and Drug Induced Liver Injury; Comorbidity; Computer Systems; Elasticity Imaging Techniques; Female; Humans; Incidence; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Reproducibility of Results; Republic of Korea; Risk Factors; Sensitivity and Specificity | 2015 |
Effects of Methotrexate on Carotid Intima-media Thickness in Patients with Rheumatoid Arthritis.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Carotid Artery Diseases; Carotid Intima-Media Thickness; Causality; Comorbidity; Female; Humans; Incidence; Male; Methotrexate; Middle Aged; Reproducibility of Results; Republic of Korea; Risk Factors; Sensitivity and Specificity | 2015 |
Plasma biomarkers of risk for death in a multicenter phase 3 trial with uniform transplant characteristics post-allogeneic HCT.
Topics: Adolescent; Adult; Allografts; Area Under Curve; Biomarkers, Tumor; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes; ROC Curve; Sensitivity and Specificity; Sirolimus; Tacrolimus; Transplantation, Homologous; Young Adult | 2017 |
Evaluation of chemotherapy response in osteosarcoma with FDG-PET.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin; Doxorubicin; Female; Fluorodeoxyglucose F18; Humans; Ifosfamide; Male; Methotrexate; Middle Aged; Osteosarcoma; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome; Young Adult | 2009 |
Assessment of residual tumour by FDG-PET: conventional imaging and clinical examination following primary chemotherapy of large and locally advanced breast cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epirubicin; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Fluorouracil; Humans; Magnetic Resonance Imaging; Mammography; Mastectomy; Methotrexate; Middle Aged; Neoadjuvant Therapy; Neoplasm, Residual; Paclitaxel; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Ultrasonography, Mammary | 2010 |
Accelerated hand bone mineral density loss is associated with progressive joint damage in hands and feet in recent-onset rheumatoid arthritis.
Topics: Absorptiometry, Photon; Adult; Aged; Antibodies, Monoclonal; Arthritis, Rheumatoid; Bone Density; Disease Progression; Drug Therapy, Combination; Female; Foot; Hand; Humans; Infliximab; Logistic Models; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prednisone; Sensitivity and Specificity; Sulfasalazine | 2010 |
RAPID3 (Routine Assessment of Patient Index Data 3) severity categories and response criteria: Similar results to DAS28 (Disease Activity Score) and CDAI (Clinical Disease Activity Index) in the RAPID 1 (Rheumatoid Arthritis Prevention of Structural Damag
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Certolizumab Pegol; Disability Evaluation; Drug Combinations; Health Status Indicators; Humans; Immunoglobulin Fab Fragments; Immunosuppressive Agents; Longitudinal Studies; Methotrexate; Outcome Assessment, Health Care; Polyethylene Glycols; Sensitivity and Specificity | 2011 |
Evaluation of liver fibrosis by transient elastography in methotrexate treated patients.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Administration Schedule; Elasticity Imaging Techniques; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Liver Cirrhosis; Logistic Models; Male; Methotrexate; Middle Aged; Prospective Studies; Psoriasis; Sensitivity and Specificity; Single-Blind Method | 2011 |
Remission in early rheumatoid arthritis: predicting treatment response.
Topics: Age Factors; Antirheumatic Agents; Arthritis, Rheumatoid; Disability Evaluation; Drug Therapy, Combination; Female; Humans; Joints; Logistic Models; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Remission Induction; Sensitivity and Specificity; Sex Factors; Treatment Outcome; United Kingdom | 2012 |
Association of baseline levels of markers of bone and cartilage degradation with long-term progression of joint damage in patients with early rheumatoid arthritis: the COBRA study.
Topics: Arthritis, Rheumatoid; Biomarkers; Blood Sedimentation; Collagen Type I; Collagen Type II; Disease Progression; Female; Humans; Male; Methotrexate; Middle Aged; Peptide Fragments; Prednisolone; Prospective Studies; Radiography; Sensitivity and Specificity; Sulfasalazine | 2002 |
Bioassay for detection of methotrexate in serum.
Topics: Animals; Antirheumatic Agents; B-Lymphocytes; Biological Assay; Cell Culture Techniques; Cell Division; Humans; Hypoxanthine Phosphoribosyltransferase; Methotrexate; Mice; Sensitivity and Specificity | 2004 |
Indirect and total costs of early rheumatoid arthritis: a randomized comparison of combined step-down prednisolone, methotrexate, and sulfasalazine with sulfasalazine alone.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Cost-Benefit Analysis; Drug Therapy, Combination; Early Diagnosis; Female; Health Care Costs; Health Expenditures; Humans; Male; Methotrexate; Middle Aged; Prednisolone; Sensitivity and Specificity; Sulfasalazine | 2004 |
A new predictive scoring system including shock index for unruptured tubal pregnancy patients.
Topics: Abortifacient Agents, Nonsteroidal; Adolescent; Adult; Blood Pressure; Chorionic Gonadotropin, beta Subunit, Human; Cohort Studies; Female; Heart Rate; Humans; Methotrexate; Middle Aged; Predictive Value of Tests; Pregnancy; Pregnancy, Tubal; Prospective Studies; ROC Curve; Sensitivity and Specificity; Severity of Illness Index; Shock; Ultrasonography | 2006 |
Magnetic resonance imaging is more sensitive than radiographs in detecting change in size of erosions in rheumatoid arthritis.
Topics: Antirheumatic Agents; Disease Progression; Drug Therapy, Combination; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Metacarpophalangeal Joint; Methotrexate; Patient Compliance; Prognosis; Rheumatic Diseases; Sensitivity and Specificity; Tumor Necrosis Factor-alpha; Wrist | 2006 |
Plasma level of CXC-chemokine CXCL12 is increased in rheumatoid arthritis and is independent of disease activity and methotrexate treatment.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Chemokine CXCL12; Chemokines, CXC; Female; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Prognosis; Reproducibility of Results; Sensitivity and Specificity; Statistics as Topic | 2006 |
Reliability and sensitivity to change of the Simple Erosion Narrowing Score compared with the Sharp-van der Heijde method for scoring radiographs in rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Methotrexate; Observer Variation; Radiography; Receptors, Tumor Necrosis Factor; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome | 2008 |
Cost-effectiveness of abatacept in patients with moderately to severely active rheumatoid arthritis and inadequate response to methotrexate.
Topics: Abatacept; Adolescent; Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cost-Benefit Analysis; Disability Evaluation; Disease Progression; Drug Costs; Female; Health Care Costs; Humans; Immunoconjugates; Male; Methotrexate; Middle Aged; Models, Econometric; Quality-Adjusted Life Years; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha | 2008 |
[Must we still operate on ectopic pregnancies?].
Topics: Chorionic Gonadotropin; Decision Trees; Female; Gestational Age; Humans; Hysteroscopy; Laparoscopy; Methotrexate; Pregnancy; Pregnancy, Ectopic; Progesterone; Prospective Studies; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Ultrasonography, Prenatal | 1993 |
Significant changes in serum AST across hepatic histological biopsy grades: prospective analysis of 3 cohorts receiving methotrexate therapy for rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Aspartate Aminotransferases; Biopsy; Chemical and Drug Induced Liver Injury; Cohort Studies; Female; Humans; Liver Diseases; Male; Methotrexate; Middle Aged; Prospective Studies; Sensitivity and Specificity | 1996 |
Cost-effectiveness of adjuvant chemotherapy with cyclophosphamide+methotrexate+fluorouracil in patients with node-positive breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Cyclophosphamide; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Methotrexate; Sensitivity and Specificity; Survival Rate | 1996 |
Serum type III procollagen aminopeptide for assessing liver damage in methotrexate-treated psoriatic patients.
Topics: Adult; Aged; Biomarkers; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Follow-Up Studies; Humans; Laminin; Liver Diseases; Methotrexate; Middle Aged; Peptide Fragments; Procollagen; Psoriasis; Sensitivity and Specificity | 1996 |
Does information from axillary dissection change treatment in clinically node-negative patients with breast cancer? An algorithm for assessment of impact of axillary dissection.
Topics: Adult; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; False Negative Reactions; Female; Fluorouracil; Hematopoietic Stem Cell Transplantation; Humans; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Mastectomy, Radical; Mastectomy, Segmental; Methotrexate; Middle Aged; Neoplasm Staging; Neoplasms, Ductal, Lobular, and Medullary; Prognosis; Sensitivity and Specificity; Tamoxifen | 1997 |
Evaluation of chemotherapy in advanced urinary bladder cancer with fast dynamic contrast-enhanced MR imaging.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Contrast Media; Doxorubicin; Female; Gadolinium DTPA; Humans; Lymphatic Metastasis; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Prospective Studies; Sensitivity and Specificity; Treatment Failure; Urinary Bladder Neoplasms; Vinblastine | 1998 |
Sensitivity to change of generic quality of life instruments in patients with rheumatoid arthritis: preliminary findings in the generic health OMERACT study. OMERACT/ILAR Task Force on Generic Quality of Life. Life Outcome Measures in Rheumatology. Intern
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Disability Evaluation; Female; Humans; Male; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Quality of Life; Sensitivity and Specificity; Surveys and Questionnaires | 1999 |
Smallest detectable difference in radiological progression.
Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Joints; Male; Methotrexate; Middle Aged; Observer Variation; Prednisolone; Radiography; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Sulfasalazine; Treatment Outcome | 1999 |
The relation between erythropoietin, hematocrit and hemoglobin in breast cancer patients on non-nephrotoxic chemotherapy.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Enzyme-Linked Immunosorbent Assay; Erythropoietin; Female; Fluorouracil; Hematocrit; Hemoglobins; Humans; Methotrexate; Neoplasm Staging; Prognosis; Sensitivity and Specificity | 1998 |
The relationship between serum levels of erythropoietin (EPO) and insulin-like growth factor-1 (ILGF-1) and hematocrit (HCT) in breast cancer patients receiving non-nephrotoxic chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Confidence Intervals; Cyclophosphamide; Doxorubicin; Erythropoietin; Female; Fluorouracil; Hematocrit; Humans; Insulin-Like Growth Factor I; Methotrexate; Middle Aged; Neoplasm Staging; Prognosis; Sensitivity and Specificity | 1998 |
Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group.
Topics: Adult; Aged; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Chi-Square Distribution; Double-Blind Method; Female; Humans; Infliximab; Infusions, Intravenous; Male; Methotrexate; Middle Aged; Placebos; Remission Induction; Sensitivity and Specificity; Tumor Necrosis Factor-alpha | 1999 |
A cost-effectiveness analysis of treatment options for patients with methotrexate-resistant rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cost-Benefit Analysis; Drug Resistance; Humans; Methotrexate; Reference Values; Sensitivity and Specificity; Therapeutic Equivalency; Treatment Outcome | 2000 |
Combined treatment of giant-cell arteritis with methotrexate and prednisone. a randomized, double-blind, placebo-controlled trial.
Topics: Adrenal Cortex Hormones; Aged; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Giant Cell Arteritis; Humans; Immunosuppressive Agents; Male; Methotrexate; Placebos; Prednisone; Recurrence; Sensitivity and Specificity; Statistics, Nonparametric | 2001 |
COBRA combination therapy in patients with early rheumatoid arthritis: long-term structural benefits of a brief intervention.
Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prednisolone; Radiography; Sensitivity and Specificity; Severity of Illness Index; Sulfasalazine; Treatment Outcome | 2002 |
A European Organization for Research and Treatment of Cancer--Genitourinary Group phase 2 study of chemotherapy in stage T3-4N0-XM0 transitional cell cancer of the bladder: evaluation of clinical response.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Female; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Staging; Prospective Studies; Remission Induction; Sensitivity and Specificity; Urinary Bladder Neoplasms | 1992 |
159 other study(ies) available for methotrexate and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Optimization and validation of an analytical method for the estimation of methotrexate in rabbit plasma.
Topics: Animals; Antimetabolites, Antineoplastic; Female; Male; Methotrexate; Molecular Structure; Rabbits; Reproducibility of Results; Sensitivity and Specificity | 2022 |
An updated matrix to predict rapid radiographic progression of early rheumatoid arthritis patients: pooled analyses from several databases.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Databases, Factual; Disease Progression; Female; Humans; Male; Methotrexate; Middle Aged; Prognosis; Radiography; Risk Factors; Sensitivity and Specificity | 2020 |
Predictors and clinical features of methotrexate (MTX) therapy for ectopic pregnancy.
Topics: Adult; Asymptomatic Diseases; Chorionic Gonadotropin, beta Subunit, Human; Conservative Treatment; Drug Monitoring; Female; Humans; Methotrexate; Pregnancy; Pregnancy, Ectopic; Prognosis; Retrospective Studies; Sensitivity and Specificity; Treatment Outcome; Young Adult | 2020 |
A distinctive staining pattern with anti-3-hydroxy-3-methyl-glutaryl-coenzyme a reductase (HMGCR) antibodies on mouse kidney.
Topics: Aged; Animals; Autoantibodies; Female; Fluorescent Antibody Technique; Humans; Hydroxymethylglutaryl CoA Reductases; Immunosuppression Therapy; Kidney; Methotrexate; Mice; Muscular Diseases; Prednisone; Sensitivity and Specificity; Staining and Labeling | 2021 |
UPLC-MS/MS method for the simultaneous quantification of pravastatin, fexofenadine, rosuvastatin, and methotrexate in a hepatic uptake model and its application to the possible drug-drug interaction study of triptolide.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Diterpenes; Drug Interactions; Epoxy Compounds; Hepatocytes; Linear Models; Male; Methotrexate; Phenanthrenes; Pravastatin; Rats, Wistar; Reproducibility of Results; Rosuvastatin Calcium; Sensitivity and Specificity; Tandem Mass Spectrometry; Terfenadine | 2021 |
Evaluation of Tubal Pregnancy After Treatment With Methotrexate by Ultrasound Elastography.
Topics: Abortifacient Agents, Nonsteroidal; Adult; Chorionic Gonadotropin, beta Subunit, Human; Elasticity Imaging Techniques; Female; Humans; Methotrexate; Pregnancy; Pregnancy, Tubal; Retrospective Studies; Sensitivity and Specificity; Treatment Outcome | 2018 |
Utility of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) as biomarker to predict therapeutic response to methotrexate in rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers, Pharmacological; Cohort Studies; Disease Progression; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Prospective Studies; Sensitivity and Specificity; Surveys and Questionnaires; Triggering Receptor Expressed on Myeloid Cells-1; Young Adult | 2017 |
Plasma 7-Hydroxymethotrexate Levels Versus Methotrexate to Predict Delayed Elimination in Children Receiving High-Dose Methotrexate.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Creatinine; Female; Humans; Male; Methotrexate; Retrospective Studies; Sensitivity and Specificity; Time Factors | 2018 |
Clinical Juvenile Arthritis Disease Activity Score proves to be a useful tool in treat-to-target therapy in juvenile idiopathic arthritis.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Female; Humans; Infant; Male; Methotrexate; Retrospective Studies; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome; Tumor Necrosis Factor-alpha; Visual Analog Scale | 2018 |
Development and validation of a rapid reverse-phase HPLC method for the determination of methotrexate from nanostructured liquid crystalline systems.
Topics: Chromatography, High Pressure Liquid; Limit of Detection; Liquid Crystals; Methotrexate; Nanostructures; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2018 |
Role of mean platelet volume and neutrophil/lymphocyte ratio to predict single-dose methotrexate treatment success in tubal ectopic pregnancy.
Topics: Abortifacient Agents, Nonsteroidal; Adult; Biomarkers; Female; Humans; Lymphocyte Count; Lymphocytes; Mean Platelet Volume; Methotrexate; Neutrophils; Pregnancy; Pregnancy, Ectopic; Pregnancy, Tubal; Sensitivity and Specificity; Treatment Outcome | 2016 |
Simultaneous determination of plasma methotrexate and 7-hydroxy methotrexate by UHPLC-MS/MS in patients receiving high-dose methotrexate therapy.
Topics: Calibration; Central Nervous System Neoplasms; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Monitoring; Folic Acid Antagonists; Humans; Kidney; Liver; Lymphoma, Non-Hodgkin; Male; Methotrexate; Sensitivity and Specificity; Tandem Mass Spectrometry | 2018 |
Various BhCG monitoring protocols for predicting the success of single-dose methotrexate in the treatment of ectopic pregnancy.
Topics: Adult; Chorionic Gonadotropin, beta Subunit, Human; Female; Humans; Methotrexate; Pregnancy; Pregnancy, Ectopic; Retrospective Studies; ROC Curve; Sensitivity and Specificity; Time Factors; Treatment Outcome | 2019 |
Development and Validation of a Sensitive UHPLC-MS/MS-Based Method for the Analysis of Folylpolyglutamate Synthetase Enzymatic Activity in Peripheral Blood Mononuclear Cells: Application in Rheumatoid Arthritis and Leukemia Patients.
Topics: Arthritis, Rheumatoid; Cell Line, Tumor; Chromatography, High Pressure Liquid; Humans; Leukocytes, Mononuclear; Methotrexate; Peptide Synthases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2019 |
Pharmacokinetic application of a bio-analytical LC-MS method developed for 5-fluorouracil and methotrexate in mouse plasma, brain and urine.
Topics: Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Drug Stability; Fluorouracil; Linear Models; Male; Mass Spectrometry; Methotrexate; Mice; Reproducibility of Results; Sensitivity and Specificity | 2013 |
Comparison of the 1987 ACR and 2010 ACR/EULAR classification criteria for rheumatoid arthritis in clinical practice: a prospective cohort study.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Early Diagnosis; Female; Foot Joints; Hand Joints; Humans; Male; Methotrexate; Middle Aged; Practice Guidelines as Topic; Prospective Studies; Radiography; Rheumatology; Sensitivity and Specificity; Symptom Assessment; Synovitis | 2013 |
An immunological biomarker to predict MTX response in early RA.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Biomarkers; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Male; Methotrexate; Middle Aged; Pilot Projects; Prognosis; Remission Induction; Sensitivity and Specificity; T-Lymphocyte Subsets; Treatment Outcome; Tumor Necrosis Factor-alpha | 2014 |
Definition of improvement in juvenile idiopathic arthritis using the juvenile arthritis disease activity score.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Biological Products; Child; Disease Progression; Female; Germany; Humans; Male; Methotrexate; Outcome Assessment, Health Care; Registries; Retrospective Studies; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome | 2014 |
A sandwich substrate for ultrasensitive and label-free SERS spectroscopic detection of folic acid / methotrexate.
Topics: Copper; Folic Acid; Membranes, Artificial; Metal Nanoparticles; Methotrexate; Sensitivity and Specificity; Silver; Spectrum Analysis, Raman | 2014 |
Tuberculin skin test and ELISPOT/T. SPOT.TB in children and adolescents with juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Brazil; Child; Enzyme-Linked Immunospot Assay; Female; Humans; Immunocompromised Host; Immunosuppressive Agents; Latent Tuberculosis; Longitudinal Studies; Male; Methotrexate; Mycobacterium tuberculosis; Prevalence; Prospective Studies; Reproducibility of Results; Sensitivity and Specificity; Tuberculin Test | 2014 |
Second-dose methotrexate in ectopic pregnancies: the role of beta human chorionic gonadotropin.
Topics: Adult; Chorionic Gonadotropin, beta Subunit, Human; Cohort Studies; Female; Humans; Methotrexate; Pregnancy; Pregnancy, Ectopic; Retrospective Studies; Sensitivity and Specificity; Treatment Failure | 2014 |
βhCG monitoring after single-dose methotrexate treatment of tubal ectopic pregnancy: is the Day 4 βhCG necessary? A retrospective cohort study.
Topics: Abortifacient Agents, Nonsteroidal; Adult; Chorionic Gonadotropin, beta Subunit, Human; Female; Humans; Methotrexate; Pregnancy; Pregnancy, Tubal; Retrospective Studies; Sensitivity and Specificity; Treatment Outcome | 2014 |
Facile synthesis of N, S-codoped fluorescent carbon nanodots for fluorescent resonance energy transfer recognition of methotrexate with high sensitivity and selectivity.
Topics: Blood Chemical Analysis; Carbon; Crystallization; Fluorescence Resonance Energy Transfer; Humans; Methotrexate; Nanoparticles; Quantum Dots; Reproducibility of Results; Sensitivity and Specificity | 2015 |
Early prediction for the requirement of second or third dose methotrexate in women with ectopic pregnancy, treated with single-dose regimen.
Topics: Abortifacient Agents, Nonsteroidal; Adult; Biomarkers; Case-Control Studies; Chorionic Gonadotropin, beta Subunit, Human; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Methotrexate; Predictive Value of Tests; Pregnancy; Pregnancy, Ectopic; Probability; Regression Analysis; Retrospective Studies; Sensitivity and Specificity; Time Factors; Ultrasonography | 2015 |
Tubal rupture in ectopic pregnancy: is it predictable?
Topics: Adolescent; Chorionic Gonadotropin; Female; Humans; Methotrexate; Predictive Value of Tests; Pregnancy; Pregnancy, Tubal; Retrospective Studies; Rupture, Spontaneous; Sensitivity and Specificity; Young Adult | 2015 |
Prediction of methotrexate intolerance in juvenile idiopathic arthritis: a prospective, observational cohort study.
Topics: Adolescent; Alanine Transaminase; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cohort Studies; Creatinine; Dose-Response Relationship, Drug; Female; Gastrointestinal Diseases; Humans; Infant; Logistic Models; Male; Methotrexate; Models, Statistical; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prospective Studies; Risk Factors; Sensitivity and Specificity; Treatment Outcome | 2015 |
Power Doppler ultrasound monitoring of response to anti-tumour necrosis factor alpha treatment in patients with rheumatoid arthritis.
Topics: Adalimumab; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Blood Sedimentation; C-Reactive Protein; Drug Therapy, Combination; Etanercept; Female; Humans; Joints; Male; Methotrexate; Middle Aged; Sensitivity and Specificity; Treatment Outcome; Tumor Necrosis Factor-alpha; Ultrasonography, Doppler; Visual Analog Scale | 2015 |
Detection of bone erosions in early rheumatoid arthritis: 3D ultrasonography versus computed tomography.
Topics: Adult; Arthritis, Rheumatoid; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Hand; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prospective Studies; Sensitivity and Specificity; Synovitis; Tomography, X-Ray Computed; Ultrasonography; Wrist Joint | 2015 |
Identification of 7 Proteins in Sera of RA Patients with Potential to Predict ETA/MTX Treatment Response.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Blood Proteins; Drug Monitoring; Etanercept; Humans; Methotrexate; Sensitivity and Specificity | 2015 |
Do we need to lower the cut point of the 2010 ACR/EULAR classification criteria for diagnosing rheumatoid arthritis?
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Early Diagnosis; False Positive Reactions; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Sensitivity and Specificity; Severity of Illness Index | 2016 |
A comparative analysis of two interferon-γ releasing assays to detect past tuberculosis infections in Japanese rheumatoid arthritis patients.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Humans; Interferon-gamma; Interferon-gamma Release Tests; Male; Methotrexate; Middle Aged; Sensitivity and Specificity; Tuberculin Test; Tuberculosis | 2016 |
MMP-3 as a predictor for structural remission in RA patients treated with MTX monotherapy.
Topics: Aged; Antirheumatic Agents; Area Under Curve; Arthritis, Rheumatoid; Biomarkers; Disease Progression; Female; Humans; Male; Matrix Metalloproteinase 3; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Remission Induction; ROC Curve; Sensitivity and Specificity | 2016 |
The usefulness of (18)F-FDG PET/CT for assessing methotrexate-associated lymphoproliferative disorder (MTX-LPD).
Topics: Aged; Aged, 80 and over; Female; Fluorodeoxyglucose F18; Glycolysis; Humans; Lymphoproliferative Disorders; Male; Methotrexate; Middle Aged; Positron Emission Tomography Computed Tomography; Radiopharmaceuticals; Retrospective Studies; Sensitivity and Specificity; Tomography, X-Ray Computed; Tumor Burden | 2016 |
Development and validation of a fast RP-HPLC method for determination of methotrexate entrapment efficiency in polymeric nanocapsules.
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Methotrexate; Nanocapsules; Polymers; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2008 |
Outcome prediction for treatment of tubal pregnancy using an intramuscular methotrexate protocol.
Topics: Abortifacient Agents, Nonsteroidal; Adolescent; Adult; Female; Humans; Injections, Intramuscular; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Pregnancy; Pregnancy, Tubal; Prognosis; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; Treatment Outcome; Ultrasonography; Young Adult | 2008 |
Cutoff value of human chorionic gonadotropin in relation to the number of methotrexate cycles in the successful treatment of ectopic pregnancy.
Topics: Abortifacient Agents, Nonsteroidal; Adult; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Methotrexate; Pregnancy; Pregnancy, Ectopic; Prognosis; Reference Values; Retrospective Studies; Sensitivity and Specificity; Treatment Failure; Treatment Outcome | 2009 |
Fluorometry of singlet oxygen generated via a photosensitized reaction using folic acid and methotrexate.
Topics: Deuterium Oxide; Fluorometry; Folic Acid; Methotrexate; Molecular Structure; Photochemistry; Photosensitizing Agents; Quantum Theory; Reproducibility of Results; Sensitivity and Specificity; Singlet Oxygen; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stereoisomerism; Time Factors | 2009 |
Sentinel lymph node biopsy after preoperative chemotherapy for breast cancer: findings from the Austrian Sentinel Node Study Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Austria; Breast Neoplasms; Cyclophosphamide; Docetaxel; Doxorubicin; Female; Fluorouracil; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Methotrexate; Middle Aged; Neoadjuvant Therapy; Preoperative Care; Retrospective Studies; Sensitivity and Specificity; Sentinel Lymph Node Biopsy; Taxoids | 2008 |
Precise gene-dose alleles for chemical genetics.
Topics: Alleles; Gene Dosage; Gene Expression Regulation, Fungal; Methotrexate; Phenotype; RNA, Fungal; Saccharomyces cerevisiae; Sensitivity and Specificity | 2009 |
Quantitative phosphorus metabolomics using nanoflow liquid chromatography-tandem mass spectrometry and culture-derived comprehensive global internal standards.
Topics: Cell Line, Tumor; Chromatography, Liquid; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; Metabolomics; Methotrexate; Phosphorus; Reference Standards; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2009 |
Effect of methotrexate on the survival of human lymphocyte cultures carrying MTHFR 677 (C>T) and MTHFR 1298 (A>C) mutations.
Topics: Alleles; Antirheumatic Agents; Designer Drugs; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Therapy; Female; Genetic Predisposition to Disease; Genotype; Humans; Lymphocytes; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Pharmacogenetics; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Sensitivity and Specificity; Tumor Cells, Cultured | 2009 |
Erythrocyte methotrexate-polyglutamate assay using fluorescence polarization immunoassay technique: application to the monitoring of patients with rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Monitoring; Erythrocytes; Female; Fluorescence Polarization Immunoassay; Humans; Male; Methotrexate; Middle Aged; Polyglutamic Acid; Sensitivity and Specificity | 2009 |
Optimization of the non-invasive 13C-sucrose breath test in a rat model of methotrexate-induced mucositis.
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Breath Tests; Carbon Isotopes; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Female; Intestine, Small; Methotrexate; Mucositis; Organ Size; Rats; Sensitivity and Specificity; Sucrase; Sucrose | 2010 |
Classification, presentation, and initial treatment of Wegener's granulomatosis in childhood.
Topics: Adolescent; Adrenal Cortex Hormones; Child; Child, Preschool; Churg-Strauss Syndrome; Cohort Studies; Cyclophosphamide; Diagnosis, Differential; Europe; Female; Glomerulonephritis; Granulomatosis with Polyangiitis; Humans; Male; Methotrexate; Microscopic Polyangiitis; Pilot Projects; Reference Standards; Sensitivity and Specificity; Societies, Medical; United States; Vasculitis | 2009 |
A novel high-performance liquid chromatography/mass spectrometry method for improved selective and sensitive measurement of methotrexate polyglutamation status in human red blood cells.
Topics: Arthritis, Juvenile; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Mass Spectrometry; Methotrexate; Polyglutamic Acid; Reproducibility of Results; Sensitivity and Specificity; Time Factors | 2009 |
[Immunosuppressive therapy and tuberculosis].
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Antitubercular Agents; Arthritis, Rheumatoid; Enzyme-Linked Immunosorbent Assay; Humans; Immunocompromised Host; Immunosuppressive Agents; Infliximab; Interferon-gamma; Isoniazid; Japan; Methotrexate; Sensitivity and Specificity; Tuberculosis; Tumor Necrosis Factor-alpha | 2010 |
PubMed had a higher sensitivity than Ovid-MEDLINE in the search for systematic reviews.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Humans; MEDLINE; Methotrexate; PubMed; Randomized Controlled Trials as Topic; Sensitivity and Specificity; Treatment Outcome | 2011 |
Classification of rheumatoid arthritis: comparison of the 1987 American College of Rheumatology criteria and the 2010 American College of Rheumatology/European League Against Rheumatism criteria.
Topics: Adult; Aged; Antirheumatic Agents; Area Under Curve; Arthritis, Rheumatoid; Female; Humans; Joints; Male; Methotrexate; Middle Aged; Sensitivity and Specificity; Severity of Illness Index | 2011 |
Nailfold capillary density is importantly associated over time with muscle and skin disease activity in juvenile dermatomyositis.
Topics: Adrenal Cortex Hormones; Capillaries; Child; Dermatomyositis; Female; Humans; Longitudinal Studies; Male; Methotrexate; Muscle, Skeletal; Nails; Predictive Value of Tests; Prognosis; Prospective Studies; Quality of Life; Regression Analysis; Retrospective Studies; Sensitivity and Specificity; Severity of Illness Index; Skin | 2011 |
High prevalence of methotrexate intolerance in juvenile idiopathic arthritis: development and validation of a methotrexate intolerance severity score.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Cross-Sectional Studies; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Methotrexate; ROC Curve; Sensitivity and Specificity; Surveys and Questionnaires | 2011 |
Pregnancy-related uterine arteriovenous malformations: experience from a single medical center.
Topics: Abortion, Incomplete; Abortion, Induced; Abortion, Spontaneous; Abruptio Placentae; Adult; Angiography; Arteriovenous Malformations; Blood Flow Velocity; Dilatation and Curettage; Endosonography; Female; Humans; Hysteroscopy; Infant, Newborn; Methotrexate; Myometrium; Pregnancy; Pregnancy Complications, Cardiovascular; Retrospective Studies; Sensitivity and Specificity; Treatment Outcome; Ultrasonography, Doppler, Color; Uterine Artery Embolization; Uterus; Young Adult | 2011 |
Ultrafast selective quantification of methotrexate in human plasma by high-throughput MALDI-isotope dilution mass spectrometry.
Topics: Deuterium; Drug Stability; Fluorescence Polarization Immunoassay; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2011 |
Assessment of intracellular methotrexate and methotrexate-polyglutamate metabolite concentrations in erythrocytes by ultrafast matrix-assisted laser desorption/ionization triple quadrupole tandem mass spectrometry.
Topics: Arthritis, Rheumatoid; Erythrocytes; Humans; Linear Models; Methotrexate; Polyglutamic Acid; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Time Factors | 2011 |
Development and validation of a liquid chromatography method for simultaneous determination of three process-related impurities: yeastolates, triton X-100 and methotrexate.
Topics: Cell Adhesion Molecules; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Culture Media; Drug Contamination; Humans; Hyaluronoglucosaminidase; Methotrexate; Octoxynol; Recombinant Proteins; Reproducibility of Results; Sensitivity and Specificity; Yeasts | 2011 |
Remission, minimal disease activity, and acceptable symptom state in juvenile idiopathic arthritis: defining criteria based on the juvenile arthritis disease activity score.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Female; Humans; Joints; Male; Methotrexate; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2012 |
Practical determination of methotrexate in serum of rheumatic patients by LC-MS/MS.
Topics: Aged; Aged, 80 and over; Antirheumatic Agents; Chromatography, Liquid; Female; Humans; Male; Methotrexate; Middle Aged; Reproducibility of Results; Rheumatic Diseases; Sensitivity and Specificity; Tandem Mass Spectrometry | 2012 |
The value of BP230 enzyme-linked immunosorbent assay in the diagnosis and immunological follow-up of bullous pemphigoid.
Topics: Aged; Aged, 80 and over; Autoantibodies; Carrier Proteins; Clobetasol; Cytoskeletal Proteins; Dystonin; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Membrane Glycoproteins; Methotrexate; Mycophenolic Acid; Nerve Tissue Proteins; Pemphigoid, Bullous; Sensitivity and Specificity; Treatment Outcome | 2012 |
Infliximab exerts no direct hepatotoxic effect on HepG2 cells in vitro.
Topics: Analysis of Variance; Antibodies, Monoclonal; Azathioprine; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatoblastoma; Humans; In Vitro Techniques; Inflammatory Bowel Diseases; Infliximab; Liver Neoplasms; Mercaptopurine; Methotrexate; Sensitivity and Specificity; Thioguanine | 2012 |
Prediction of response of collagen-induced arthritis rats to methotrexate: an (1)H-NMR-based urine metabolomic analysis.
Topics: Animals; Antirheumatic Agents; Arthritis; Biomarkers; Collagen Type II; Dose-Response Relationship, Drug; Immunosuppressive Agents; Magnetic Resonance Spectroscopy; Male; Metabolome; Methotrexate; Proteome; Protons; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome | 2012 |
How much difference does the age at onset make in early arthritis patients? Comparison between the ACR 1987 and the ACR/EULAR 2010 classification criteria for rheumatoid arthritis at the time of diagnosis.
Topics: Adolescent; Adult; Age of Onset; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Disease Progression; Female; Humans; Male; Methotrexate; Middle Aged; Prognosis; Sensitivity and Specificity; Severity of Illness Index | 2013 |
Determination of erythrocyte methotrexate polyglutamates by liquid chromatography/tandem mass spectrometry after low-dose methotrexate therapy in Chinese patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; China; Chromatography, Liquid; Dose-Response Relationship, Drug; Drug Stability; Erythrocytes; Humans; Linear Models; Liquid-Liquid Extraction; Methotrexate; Polyglutamic Acid; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2012 |
Pretreatment with valproic acid, a histone deacetylase inhibitor, enhances the sensitivity of the peripheral blood micronucleus assay in rodents.
Topics: Animals; Cyclophosphamide; Erythrocytes; Histone Deacetylase Inhibitors; Male; Methotrexate; Mice; Micronucleus Tests; Mutagens; Rats; Rats, Sprague-Dawley; Reticulocytes; Sensitivity and Specificity; Valproic Acid; Zidovudine | 2013 |
Measuring methotrexate polyglutamates in red blood cells: a new LC-MS/MS-based method.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Drug Monitoring; Erythrocytes; Humans; Limit of Detection; Methotrexate; Polyglutamic Acid; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2013 |
Vitreoretinal lymphoma: a 20-year review of incidence, clinical and cytologic features, treatment, and outcomes.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; British Columbia; Combined Modality Therapy; Cytarabine; Eye Neoplasms; False Positive Reactions; Female; Humans; Incidence; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Radiotherapy; Retinal Neoplasms; Retrospective Studies; Sensitivity and Specificity; Survival Rate; Tomography, X-Ray Computed; Treatment Outcome; Vitrectomy; Vitreous Body | 2013 |
Ultrasound can improve the accuracy of the 2010 American College of Rheumatology/European League against rheumatism classification criteria for rheumatoid arthritis to predict the requirement for methotrexate treatment.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Sensitivity and Specificity; Synovitis; Ultrasonography | 2013 |
Defining erosive disease typical of RA in the light of the ACR/EULAR 2010 criteria for rheumatoid arthritis; results of the data driven phase.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Arthrography; Diagnosis-Related Groups; Disease Progression; Europe; Female; Humans; Joints; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Rheumatology; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome | 2013 |
Comparison of UV derivative-spectrophotometry and partial least-squares (PLS-1) calibration for determination of methotrexate and leucovorin in biological fluids.
Topics: Antimetabolites, Antineoplastic; Calibration; Drug Monitoring; Leucovorin; Methotrexate; Models, Statistical; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2002 |
Quantitative assessment of the clavicle radiostructure as a tool for estimation of the osteopathic effect of breast cancer chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Diseases; Breast Neoplasms; Clavicle; Cyclophosphamide; Female; Fluorouracil; Humans; Image Processing, Computer-Assisted; Methotrexate; Middle Aged; Osteoporosis; Premenopause; Radiography; Reproducibility of Results; Sensitivity and Specificity; Software | 2002 |
Biological monitoring of hospital personnel occupationally exposed to antineoplastic agents.
Topics: Adult; Antineoplastic Agents, Alkylating; Chromatography, High Pressure Liquid; Cyclophosphamide; Environmental Monitoring; Female; Humans; Ifosfamide; Male; Mass Spectrometry; Methotrexate; Occupational Exposure; Personnel, Hospital; Platinum; Sensitivity and Specificity | 2002 |
Effects of antirheumatic therapy on serum lipid levels in patients with rheumatoid arthritis: a prospective study.
Topics: Adult; Aged; Analysis of Variance; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Chi-Square Distribution; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lipids; Male; Methotrexate; Middle Aged; Probability; Prospective Studies; Sensitivity and Specificity; Severity of Illness Index; Triglycerides | 2002 |
Simultaneous analysis of sulfur-containing excitatory amino acids using micellar electrokinetic chromatography with diode array and laser-induced fluorescence detection.
Topics: Amino Acids, Sulfur; Antimetabolites, Antineoplastic; Central Nervous System; Chromatography, Micellar Electrokinetic Capillary; Drug Stability; Excitatory Amino Acids; Fluoresceins; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Lasers; Methotrexate; Sensitivity and Specificity; Spectrometry, Fluorescence; Succinimides | 2002 |
Methotrexate treatment and mortality in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cardiovascular Diseases; Drug Therapy, Combination; Humans; Methotrexate; Proportional Hazards Models; Research Design; Sensitivity and Specificity | 2002 |
Early changes in [18F]FLT uptake after chemotherapy: an experimental study.
Topics: Antineoplastic Agents; Artifacts; Carcinoma, Squamous Cell; Cell Survival; Cisplatin; Deoxycytidine; Dideoxynucleosides; Dose-Response Relationship, Drug; Esophageal Neoplasms; Fluorodeoxyglucose F18; Fluorouracil; Gemcitabine; Humans; Methotrexate; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Statistics as Topic; Tumor Cells, Cultured | 2002 |
Persistent ectopic pregnancy after linear salpingotomy: a non-predictable complication to conservative surgery for tubal gestation.
Topics: Abortifacient Agents; Administration, Oral; Adult; Chorionic Gonadotropin; Cohort Studies; Disease-Free Survival; Female; Humans; Injections, Intramuscular; Medical Records; Methotrexate; Postoperative Complications; Predictive Value of Tests; Pregnancy; Pregnancy, Ectopic; Retrospective Studies; ROC Curve; Salpingostomy; Sensitivity and Specificity | 2002 |
Thymidylate synthase protein expression in colorectal cancer metastases predicts for clinical outcome to leucovorin-modulated bolus or infusional 5-fluorouracil but not methotrexate-modulated bolus 5-fluorouracil.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy, Needle; Chi-Square Distribution; Cohort Studies; Colorectal Neoplasms; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Immunohistochemistry; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Predictive Value of Tests; Probability; Prognosis; Sensitivity and Specificity; Survival Rate; Thymidylate Synthase; Treatment Outcome | 2002 |
Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate.
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Female; Genetic Testing; Homozygote; Humans; Leukemia; Male; Maximum Tolerated Dose; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Pharmacogenetics; Polymorphism, Genetic; Predictive Value of Tests; Probability; Retrospective Studies; Risk Assessment; Sensitivity and Specificity | 2002 |
The immunoassay of methotrexate by capillary electrophoresis with laser-induced fluorescence detection.
Topics: Electrophoresis, Capillary; Hydrogen-Ion Concentration; Immunoassay; Lasers; Methotrexate; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Vancomycin | 2003 |
Identification of chemotherapeutic refractory cases based on human chorionic gonadotropin values among patients with low-risk persistent trophoblastic disease treated with 8-day methotrexate-folinic acid.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chorionic Gonadotropin; Female; Humans; Leucovorin; Lung Neoplasms; Methotrexate; Pregnancy; Reference Values; Sensitivity and Specificity; Treatment Outcome; Trophoblastic Neoplasms; Uterine Neoplasms | 2003 |
Effect of immunostimulatory ribomunyl on the preventive treatment of rat adjuvant arthritis with cyclosporine and methotrexate.
Topics: Administration, Oral; Animals; Antigens, Bacterial; Arthritis, Experimental; Cyclosporine; Disease Models, Animal; Drug Therapy, Combination; Immunosuppressive Agents; Inflammation Mediators; Male; Methotrexate; Random Allocation; Rats; Rats, Inbred Lew; Reference Values; Sensitivity and Specificity; Treatment Outcome | 2003 |
HPLC determination of erythrocyte methotrexate polyglutamates after low-dose methotrexate therapy in patients with rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Calibration; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Methotrexate; Monitoring, Physiologic; Polyglutamic Acid; Reproducibility of Results; Sensitivity and Specificity | 2003 |
Simultaneous determination of methotrexate and its eight metabolites in human whole blood by capillary zone electrophoresis.
Topics: Antimetabolites, Antineoplastic; Electrophoresis, Capillary; Folic Acid Antagonists; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reproducibility of Results; Sensitivity and Specificity | 2003 |
Simultaneous determination of L- and D-methotrexate using a sequential injection analysis/amperometric biosensors system.
Topics: Amino Acid Oxidoreductases; Biosensing Techniques; Complex Mixtures; Electrochemistry; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Flow Injection Analysis; Horseradish Peroxidase; Hydrogen Peroxide; L-Amino Acid Oxidase; Methotrexate; Microchemistry; Online Systems; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism | 2003 |
Comparison of rheumatoid arthritis clinical trial outcome measures: a simulation study.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Clinical Trials as Topic; Computer Simulation; Cyclooxygenase Inhibitors; Female; Humans; Lactones; Male; Methotrexate; Middle Aged; Models, Statistical; Sensitivity and Specificity; Severity of Illness Index; Sulfones; Treatment Outcome | 2003 |
Evaluating changes in health status: sensitivity to change of the modified Arabic Health Assessment Questionnaire in patients with rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cross-Cultural Comparison; Egypt; Female; Health Status; Health Status Indicators; Humans; Male; Methotrexate; Middle Aged; Prospective Studies; Recovery of Function; Sensitivity and Specificity; Surveys and Questionnaires; United States | 2003 |
Recovering the true targets of specific ligands by virtual screening of the protein data bank.
Topics: Algorithms; Amino Acid Sequence; Binding Sites; Biotin; Computational Biology; Computer Simulation; Crystallography, X-Ray; Databases, Protein; Drug Evaluation, Preclinical; Ligands; Methotrexate; Molecular Sequence Data; Molecular Weight; Proteins; Purine Nucleosides; Ribonucleosides; Sensitivity and Specificity; Software; Substrate Specificity; Tamoxifen | 2004 |
Development of analytical methods for the determination of sub-ppm concentrations of palladium and iron in methotrexate.
Topics: Drug Contamination; Iron; Methotrexate; Palladium; Particle Size; Sensitivity and Specificity; Technology, Pharmaceutical | 2004 |
Correlation between ligand-receptor affinity and the transcription readout in a yeast three-hybrid system.
Topics: Escherichia coli; Fluorescence; Genes, Reporter; Ligands; Methotrexate; Models, Molecular; Protein Conformation; Saccharomyces cerevisiae; Sensitivity and Specificity; Tacrolimus Binding Protein 1A; Tetrahydrofolate Dehydrogenase; Transcription, Genetic; Two-Hybrid System Techniques | 2004 |
In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Biomarkers; Collagen; Disease Models, Animal; Endopeptidases; Fluorescence; Histocytochemistry; Male; Methotrexate; Mice; Mice, Inbred DBA; Sensitivity and Specificity; Treatment Outcome | 2004 |
Determination of the chiral and achiral related substances of methotrexate by cyclodextrin-modified micellar electrokinetic chromatography.
Topics: beta-Cyclodextrins; Chromatography, Micellar Electrokinetic Capillary; Drug Contamination; Electrolytes; Methotrexate; Molecular Structure; Reproducibility of Results; Sensitivity and Specificity; Sodium Dodecyl Sulfate; Solvents; Stereoisomerism; Surface-Active Agents | 2004 |
A novel breath test for the non-invasive assessment of small intestinal mucosal injury following methotrexate administration in the rat.
Topics: Analysis of Variance; Animals; Breath Tests; Disease Models, Animal; Injections, Subcutaneous; Intestinal Mucosa; Intestine, Small; Male; Methotrexate; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Sucrose | 2004 |
Enhanced Fcgamma receptor I, alphaMbeta2 integrin receptor expression by monocytes and neutrophils in rheumatoid arthritis: interaction with platelets.
Topics: Adult; Aged; Antibodies, Monoclonal; Arthritis, Rheumatoid; Biomarkers; Blood Platelets; Case-Control Studies; Female; Flow Cytometry; Humans; Infliximab; Integrins; Male; Methotrexate; Middle Aged; Monocytes; Neutrophils; P-Selectin; Probability; Prognosis; Receptors, IgG; Reference Values; Sensitivity and Specificity; Severity of Illness Index; Statistics, Nonparametric | 2004 |
Folate, homocysteine, and cobalamin status in patients with rheumatoid arthritis treated with methotrexate, and the effect of low dose folic acid supplement.
Topics: Arthritis, Rheumatoid; Biomarkers; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methotrexate; Probability; Prospective Studies; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Single-Blind Method; Treatment Outcome; Vitamin B 12 | 2004 |
Guidelines for blood test monitoring of methotrexate toxicity in juvenile idiopathic arthritis.
Topics: Adolescent; Alanine Transaminase; Arthritis, Juvenile; Aspartate Aminotransferases; Blood Cell Count; Blood Chemical Analysis; Child; Child, Preschool; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Female; Guideline Adherence; Humans; Male; Maximum Tolerated Dose; Methotrexate; Practice Guidelines as Topic; Prospective Studies; Risk Assessment; Sensitivity and Specificity | 2004 |
Interference of 7-hydroxymethotrexate with the determination of methotrexate in plasma samples from children with acute lymphoblastic leukemia employing routine clinical assays.
Topics: Child; Chromatography, High Pressure Liquid; Humans; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2005 |
A new high-performance liquid chromatographic/electrospray ionization tandem mass spectrometric method for the simultaneous determination of cyclophosphamide, methotrexate and 5-fluorouracil as markers of surface contamination for occupational exposure mo
Topics: Air Pollutants, Occupational; Calibration; Chromatography, High Pressure Liquid; Cyclophosphamide; Fluorouracil; Methotrexate; Occupational Exposure; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2005 |
Clinical and radiological disease-course in a Swedish DMARD-treated early RA-inception cohort: an observational study.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gold Sodium Thiomalate; Humans; Male; Methotrexate; Middle Aged; Pain Measurement; Prognosis; Radiography; Registries; Sensitivity and Specificity; Severity of Illness Index; Sulfasalazine; Sweden; Treatment Outcome | 2004 |
Capillary electrophoretic determination of methotrexate, leucovorin and folic acid in human urine.
Topics: Biomarkers; Drug Stability; Electrophoresis, Capillary; Folic Acid; Humans; Hydrogen-Ion Concentration; Leucovorin; Methotrexate; Osmolar Concentration; Reproducibility of Results; Sensitivity and Specificity; Temperature | 2005 |
Worse survival for TP53 (p53)-mutated breast cancer patients receiving adjuvant CMF.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Cohort Studies; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; Genetic Markers; Humans; Methotrexate; Middle Aged; Mutation; Neoplasm Staging; Neoplasms, Hormone-Dependent; Polymerase Chain Reaction; Probability; Prognosis; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Survival Analysis; Tamoxifen | 2005 |
Capillary electrophoretic determination of triamterene, methotrexate, and creatinine in human urine.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Child; Child, Preschool; Creatinine; Diuretics; Electrophoresis, Capillary; Female; Humans; Hydrogen-Ion Concentration; Male; Methotrexate; Molecular Structure; Pregnancy; Reproducibility of Results; Sensitivity and Specificity; Temperature; Time Factors; Triamterene | 2005 |
Quantitative magnetic resonance imaging of the hands and wrists of children with juvenile rheumatoid arthritis.
Topics: Adolescent; Antirheumatic Agents; Arthritis, Juvenile; Child; Child, Preschool; Contrast Media; Drug Therapy, Combination; Etanercept; Feasibility Studies; Female; Hand; Humans; Immunoglobulin G; Magnetic Resonance Imaging; Male; Methotrexate; Pain Measurement; Physical Examination; Prognosis; Prospective Studies; Radiographic Image Enhancement; Receptors, Tumor Necrosis Factor; Sensitivity and Specificity; Severity of Illness Index; Wrist | 2005 |
Influence of methylenetetrahydrofolate reductase polymorphisms on efficacy and toxicity of methotrexate in patients with juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Chi-Square Distribution; Child; Child, Preschool; Cohort Studies; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Genetic Markers; Humans; Male; Maximum Tolerated Dose; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome | 2005 |
Methotrexate causes oxidative stress in rat kidney tissues.
Topics: Animals; Biomarkers; Disease Models, Animal; Female; Glutathione Peroxidase; Infusions, Intravenous; Kidney; Lipid Peroxidation; Malondialdehyde; Methotrexate; Oxidative Stress; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Statistics, Nonparametric; Superoxide Dismutase; Tissue Culture Techniques | 2005 |
Evaluation of chemotherapy with magnetic resonance imaging in patients with regionally metastatic or unresectable bladder cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Contrast Media; Doxorubicin; Female; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prospective Studies; Sensitivity and Specificity; Survival Analysis; Treatment Outcome; Urinary Bladder Neoplasms; Vinblastine | 2006 |
Risk factors for vertebral fracture in menopausal or postmenopausal Japanese women with rheumatoid arthritis: a cross-sectional and longitudinal study.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cross-Sectional Studies; Female; Humans; Incidence; Japan; Longitudinal Studies; Lumbar Vertebrae; Menopause; Methotrexate; Middle Aged; Osteoclasts; Osteoporosis; Postmenopause; Risk Factors; Sensitivity and Specificity; Spinal Fractures; Spine; Steroids; Time Factors | 2006 |
Do serum beta-human chorionic gonadotropin levels on day 4 following methotrexate treatment of patients with ectopic pregnancy predict successful single-dose therapy?
Topics: Abortifacient Agents, Nonsteroidal; Adolescent; Adult; Biomarkers; Chorionic Gonadotropin, beta Subunit, Human; Drug Administration Schedule; Female; Humans; Methotrexate; Predictive Value of Tests; Pregnancy; Pregnancy, Ectopic; Retrospective Studies; Sensitivity and Specificity | 2006 |
A novel assay for monitoring internalization of nanocarrier coupled antibodies.
Topics: Antibodies, Neoplasm; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Doxorubicin; Histidine; Humans; Immunoglobulin Variable Region; Immunologic Techniques; Ligands; Lipid Bilayers; Lipid Metabolism; Liposomes; Methotrexate; Nickel; Oligopeptides; Receptor, ErbB-2; Sensitivity and Specificity | 2006 |
[Meningeal carcinomatosis].
Topics: Adult; Antimetabolites, Antineoplastic; Brain; Brain Neoplasms; Carcinoma; Diagnosis, Differential; Female; Gadolinium; Humans; Hydrocephalus; Injections, Spinal; Magnetic Resonance Imaging; Meningeal Neoplasms; Methotrexate; Prognosis; Sensitivity and Specificity; Spinal Puncture; Tomography, X-Ray Computed | 2006 |
Primary tumor levels of tissue inhibitor of metalloproteinases-1 are predictive of resistance to chemotherapy in patients with metastatic breast cancer.
Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cyclophosphamide; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Sensitivity and Specificity; Tissue Inhibitor of Metalloproteinase-1; Treatment Outcome | 2006 |
[Breast cancer in young women in the south of Tunisia].
Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mammography; Mastectomy; Methotrexate; Middle Aged; Multivariate Analysis; Neoplasm Staging; Prognosis; Radiotherapy, Adjuvant; Retrospective Studies; Risk Factors; Sensitivity and Specificity; Survival Analysis; Time Factors; Treatment Outcome; Tunisia | 2006 |
Determination of methotrexate and its major metabolite 7-hydroxymethotrexate in mouse plasma and brain tissue by liquid chromatography-tandem mass spectrometry.
Topics: Animals; Antimetabolites, Antineoplastic; Brain; Brain Neoplasms; Chromatography, Liquid; Methotrexate; Mice; Mice, Inbred C57BL; Microdialysis; Molecular Structure; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2007 |
Prognostic value of human chorionic gonadotropin changes after methotrexate injection for ectopic pregnancy.
Topics: Abortifacient Agents, Nonsteroidal; Chorionic Gonadotropin; Female; Humans; Injections; Methotrexate; Predictive Value of Tests; Pregnancy; Pregnancy Tests; Pregnancy, Ectopic; Prognosis; Sensitivity and Specificity | 2007 |
An improved application for the enzyme multipled immunoassay technique for caffeine, amikacin, and methotrexate assays on the Dade-Behring Dimension RxL Max clinical chemistry system.
Topics: Amikacin; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Caffeine; Central Nervous System Stimulants; Drug Monitoring; Enzyme-Linked Immunosorbent Assay; Humans; Methotrexate; Sensitivity and Specificity | 2007 |
An index of only patient-reported outcome measures, routine assessment of patient index data 3 (RAPID3), in two abatacept clinical trials: similar results to disease activity score (DAS28) and other RAPID indices that include physician-reported measures.
Topics: Abatacept; Activities of Daily Living; Antirheumatic Agents; Arthritis, Rheumatoid; Evaluation Studies as Topic; Female; Health Status Indicators; Humans; Immunoconjugates; Inflammation; Male; Medical Records; Methotrexate; Multicenter Studies as Topic; Pain Measurement; Patient Participation; Patient Satisfaction; Physicians; Probability; Randomized Controlled Trials as Topic; Range of Motion, Articular; Sensitivity and Specificity; Severity of Illness Index; Statistics, Nonparametric; Treatment Outcome | 2008 |
Development of a chemical screening system using aqueorin-fused protein.
Topics: Aequorin; Drug Delivery Systems; Immunomagnetic Separation; Luminescent Measurements; Methotrexate; Protein Binding; Protein Interaction Mapping; Sensitivity and Specificity; Tetrahydrofolate Dehydrogenase | 2008 |
Measuring clinical enthesitis in psoriatic arthritis: assessment of existing measures and development of an instrument specific to psoriatic arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Psoriatic; Cohort Studies; Female; Humans; Male; Methotrexate; Middle Aged; Randomized Controlled Trials as Topic; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Treatment Outcome | 2008 |
Serum levels of interleukin-10 in patients with diffuse large cell lymphoma: lack of correlation with prognosis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Cisplatin; Cyclophosphamide; Cytarabine; Doxorubicin; Enzyme-Linked Immunosorbent Assay; Etoposide; Female; Follow-Up Studies; Humans; Ifosfamide; Interleukin-10; Life Tables; Lymphoma, Large B-Cell, Diffuse; Male; Mesna; Methotrexate; Methylprednisolone Hemisuccinate; Middle Aged; Mitoxantrone; Neoplasm Proteins; Prognosis; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Survival Analysis; Treatment Outcome; Vincristine | 1995 |
Retinoic acid and methotrexate specifically increase PHA-E-lectin binding to a 67-kDa glycoprotein in LA-N-1 human neuroblastoma cells.
Topics: Amidohydrolases; Antibodies; Cell Differentiation; Cell Division; Chromatography, Affinity; Humans; Lectins; Membrane Glycoproteins; Methotrexate; Neoplasm Proteins; Neuroblastoma; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Phytohemagglutinins; Protein Binding; Sensitivity and Specificity; Sepharose; Serum Albumin, Bovine; Staining and Labeling; Tretinoin; Tumor Cells, Cultured | 1995 |
Methotrexate therapy and liver fibrosis: are human prolyl hydroxylase and type IV collagen reliable and sensitive markers?
Topics: Biomarkers; Collagen; Humans; Liver Cirrhosis; Methotrexate; Procollagen-Proline Dioxygenase; Sensitivity and Specificity | 1995 |
The total costs of drug therapy for rheumatoid arthritis. A model based on costs of drug, monitoring, and toxicity.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Boston; Decision Trees; Diagnosis-Related Groups; Drug Costs; Drug Monitoring; Gold; Health Care Costs; Hospitals, University; Humans; Hydroxychloroquine; Massachusetts; Methotrexate; Models, Economic; New Hampshire; Penicillamine; Sensitivity and Specificity | 1995 |
The cost-effectiveness of liver biopsy in rheumatoid arthritis patients treated with methotrexate.
Topics: Arthritis, Rheumatoid; Biopsy; Cost-Benefit Analysis; Decision Support Techniques; Decision Trees; Female; Humans; Life Expectancy; Liver; Liver Cirrhosis; Methotrexate; Middle Aged; Quality of Life; Sensitivity and Specificity; Value of Life | 1995 |
Monocyte chemoattractant protein 1 and interleukin 8 production by rheumatoid synoviocytes. Effects of anti-rheumatic drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cells, Cultured; Chemokine CCL2; Chemotactic Factors; Cytokines; Dexamethasone; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gold Sodium Thiomalate; Humans; Interleukin-1; Interleukin-8; Kinetics; Methotrexate; Prostaglandins; Prostaglandins E; Sensitivity and Specificity; Synovial Membrane | 1994 |
Comparison of methods for identifying early methotrexate-induced hepatotoxicity in patients with rheumatoid arthritis.
Topics: Adult; Aged; Alanine Transaminase; Aminopyrine; Arthritis, Rheumatoid; Aspartate Aminotransferases; Biopsy; Breath Tests; Clinical Enzyme Tests; Humans; Imino Acids; Liver; Liver Cirrhosis; Methotrexate; Middle Aged; Organotechnetium Compounds; Predictive Value of Tests; Radionuclide Imaging; Sensitivity and Specificity; Technetium Tc 99m Disofenin | 1993 |
Intra- and perivesical tumor growth in preoperative staging of bladder cancer: the role of transrectal ultrasonography and high resolution magnetic resonance imaging.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Combined Modality Therapy; Epirubicin; Female; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Neoplasm Staging; Preoperative Care; Rectum; Sensitivity and Specificity; Ultrasonography; Urinary Bladder Neoplasms; Vinblastine | 1993 |
Locally advanced breast carcinoma: accuracy of mammography versus clinical examination in the prediction of residual disease after chemotherapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Cyclophosphamide; Doxorubicin; Estrogens, Conjugated (USP); Female; Fluorouracil; Humans; Mammography; Methotrexate; Middle Aged; Neoplasm, Residual; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity; Tamoxifen | 1996 |
Determination of methotrexate and 7-hydroxymethotrexate by liquid chromatography for routine monitoring of plasma levels.
Topics: Acetonitriles; Analysis of Variance; Calibration; Chromatography, High Pressure Liquid; Fluorescence Polarization Immunoassay; Humans; Linear Models; Methotrexate; Reproducibility of Results; Sensitivity and Specificity | 1995 |
Cost evaluation of novel therapeutics in rheumatoid arthritis (CENTRA): a decision analysis model.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cost-Benefit Analysis; Decision Support Techniques; Gold; Humans; Immunosuppressive Agents; Methotrexate; Sensitivity and Specificity | 1996 |
Determination of methotrexate in serum by high-performance liquid chromatography.
Topics: Acetonitriles; Antimetabolites, Antineoplastic; Chromatography, High Pressure Liquid; Humans; Methotrexate; Sensitivity and Specificity; Theophylline | 1996 |
Validation of the French version of the arthritis impact measurement scales 2 and comparison with the french version of the Nottingham Health Profile. "Quality of Life in Rheumatology" Task Force.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Disease Progression; England; Female; France; Health Status; Health Status Indicators; Humans; Male; Methotrexate; Middle Aged; Psychometrics; Quality of Life; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Surveys and Questionnaires | 1996 |
Validity, reliability, and sensitivity to change of a French version of the arthritis impact measurement scales 2 (AIMS2) in patients with rheumatoid arthritis treated with methotrexate.
Topics: Activities of Daily Living; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Demography; Factor Analysis, Statistical; Female; France; Humans; Male; Methotrexate; Middle Aged; Quality of Life; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Surveys and Questionnaires | 1996 |
Radioreceptor assay for sirolimus.
Topics: Carrier Proteins; Chromatography, High Pressure Liquid; Cyclosporine; DNA-Binding Proteins; Heat-Shock Proteins; Humans; Immunosuppressive Agents; Methanol; Methotrexate; Polyenes; Radioligand Assay; Reproducibility of Results; Sensitivity and Specificity; Sirolimus; Tacrolimus Binding Proteins | 1996 |
The AIMS2-SF: a short form of the Arthritis Impact Measurement Scales 2. French Quality of Life in Rheumatology Group.
Topics: Activities of Daily Living; Affect; Arthritis, Rheumatoid; Health Status; Humans; Interpersonal Relations; Methotrexate; Psychometrics; Sensitivity and Specificity; Surveys and Questionnaires | 1997 |
Detectable molecular residual disease at the beginning of maintenance therapy indicates poor outcome in children with T-cell acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biomarkers, Tumor; Blotting, Southern; Bone Marrow; Child; Child, Preschool; Cohort Studies; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; DNA, Neoplasm; Evaluation Studies as Topic; Female; Fluorometry; Gene Rearrangement, delta-Chain T-Cell Antigen Receptor; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Humans; Immunophenotyping; Infant; Italy; Leucovorin; Leukemia-Lymphoma, Adult T-Cell; Male; Mercaptopurine; Methotrexate; Neoplasm, Residual; Neoplastic Stem Cells; Nucleic Acid Hybridization; Polymerase Chain Reaction; Prednisone; Prognosis; Prospective Studies; Receptors, Antigen, T-Cell, gamma-delta; Remission Induction; Sensitivity and Specificity; Treatment Outcome; Vincristine | 1997 |
[Urinary lysozyme, beta-2-microglobulin, and alpha-glucosidase during cisplatin therapy].
Topics: alpha-Glucosidases; Antineoplastic Combined Chemotherapy Protocols; beta 2-Microglobulin; Betamethasone; Biomarkers; Bleomycin; Cisplatin; Diuresis; Fluid Therapy; Humans; Kidney Diseases; Kidney Function Tests; Kidney Tubules; Methotrexate; Mouth Neoplasms; Muramidase; Neoplasm Proteins; Predictive Value of Tests; Sensitivity and Specificity; Vincristine | 1983 |
Cost-effectiveness and cost-benefit analysis of using methotrexate vs Goeckerman therapy for psoriasis. A pilot study.
Topics: Cost-Benefit Analysis; Dermatologic Agents; Humans; Methotrexate; Pilot Projects; Psoriasis; Sensitivity and Specificity; Ultraviolet Therapy | 1998 |
Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Coloring Agents; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Folic Acid Antagonists; HL-60 Cells; Humans; Infant; Infant, Newborn; Leukemia-Lymphoma, Adult T-Cell; Male; Methotrexate; Neoplasm Proteins; Neoplastic Stem Cells; Polyglutamic Acid; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sensitivity and Specificity; Staining and Labeling; Tetrazolium Salts; Thiazoles; Thymidylate Synthase; U937 Cells | 1999 |
Dihydrofolate reductase enzyme inhibition assay for plasma methotrexate determination using a 96-well microplate reader.
Topics: Folic Acid Antagonists; Humans; Methotrexate; Reproducibility of Results; Sensitivity and Specificity; Temperature; Tetrahydrofolate Dehydrogenase | 1999 |
Improved high-performance liquid chromatography determination of methotrexate and its major metabolite in plasma using a poly(styrene-divinylbenzene) column.
Topics: Antimetabolites, Antineoplastic; Chromatography, High Pressure Liquid; Humans; Methotrexate; Polystyrenes; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 1999 |
High-performance liquid chromatography of methotrexate for environmental monitoring of surface contamination in hospital departments and assessment of occupational exposure.
Topics: Antimetabolites, Antineoplastic; Calibration; Chromatography, High Pressure Liquid; Environmental Monitoring; Hospital Departments; Humans; Hydrogen-Ion Concentration; Methotrexate; Occupational Exposure; Personnel, Hospital; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 1999 |
[The presence of minimal residual disease during induction therapy is a reliable factor for the prognosis of recurrence in children with standard-risk B-cell precursor acute lymphoblastic leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; DNA Primers; Genes, T-Cell Receptor delta; Humans; Mercaptopurine; Methotrexate; Molecular Sequence Data; Neoplasm, Residual; Polymerase Chain Reaction; Prednisone; Prognosis; Recurrence; Retrospective Studies; Risk Factors; Sensitivity and Specificity; Vincristine | 1999 |
Liquid chromatographic analysis and preliminary pharmacokinetics of methotrexate in cancer patients co-treated with docetaxel.
Topics: Acetone; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Chemical Precipitation; Chromatography, High Pressure Liquid; Docetaxel; Humans; Hydroxylation; Kinetics; Methanol; Methotrexate; Neoplasms; Paclitaxel; Rats; Rats, Wistar; Sensitivity and Specificity; Taxoids | 1999 |
Determination of methotrexate in human urine at trace levels by solid phase extraction and high-performance liquid chromatography/tandem mass spectrometry.
Topics: Antimetabolites, Antineoplastic; Calibration; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Methotrexate; Occupational Exposure; Personnel, Hospital; Reproducibility of Results; Sensitivity and Specificity | 2000 |
Tumor markers CEA, CA19-9 and CA125 in monitoring of response to systemic chemotherapy in patients with advanced gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; CA-125 Antigen; CA-19-9 Antigen; Camptothecin; Carcinoembryonic Antigen; Cisplatin; Female; Fluorouracil; Humans; Irinotecan; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Prognosis; Sensitivity and Specificity; Stomach Neoplasms; Survival Rate | 1999 |
How effective is extensive nonsurgical treatment of patients with clinically active Crohn's disease of the terminal ileum in preventing surgery?
Topics: Adult; Crohn Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Ileitis; Immunosuppressive Agents; Jejunoileal Bypass; Logistic Models; Male; Methotrexate; Middle Aged; Multivariate Analysis; Reference Values; Retrospective Studies; Secondary Prevention; Sensitivity and Specificity; Severity of Illness Index; Steroids; Treatment Outcome | 2001 |
Simplified method of heterotopic rat heart transplantation using the cuff technique: application to sublethal dose protocol of methotrexate on allograft survival.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Graft Rejection; Graft Survival; Heart Transplantation; Male; Methotrexate; Microsurgery; Rats; Rats, Inbred Lew; Sensitivity and Specificity; Survival Rate; Transplantation Immunology; Transplantation, Heterologous | 2001 |
Delay of the diagnostic lumbar puncture and intrathecal chemotherapy in children with acute lymphoblastic leukemia who undergo routine corticosteroid testing: Tokyo Children's Cancer Study Group study L89-12.
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Disease-Free Survival; Drug Screening Assays, Antitumor; Female; Follow-Up Studies; Glucocorticoids; Humans; Infant; Injections, Spinal; Japan; Life Tables; Male; Methotrexate; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Proportional Hazards Models; Risk; Sensitivity and Specificity; Spinal Puncture; Time Factors; Treatment Outcome | 2001 |
The impact of p53 status on cellular sensitivity to antifolate drugs.
Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Mutational Analysis; DNA, Neoplasm; Dose-Response Relationship, Drug; Folic Acid Antagonists; Gene Expression Regulation, Neoplastic; Genotype; Glutamates; Guanine; Humans; Methotrexate; Mutation; Pemetrexed; Quinazolines; Sensitivity and Specificity; Tetrahydrofolates; Thiophenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Multiple-sprayer tandem mass spectrometry with parallel high flow extraction and parallel separation for high-throughput quantitation in biological fluids.
Topics: Animals; Methotrexate; Rats; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2001 |
Sensitivity of soft tissue sarcoma cell lines to chemotherapeutic agents: identification of ecteinascidin-743 as a potent cytotoxic agent.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Cycle; Cell Survival; Dioxoles; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Humans; Inhibitory Concentration 50; Isoquinolines; Methotrexate; Proto-Oncogene Proteins c-bcl-2; Retinoblastoma Protein; Sarcoma; Sensitivity and Specificity; Tetrahydroisoquinolines; Trabectedin; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
[Prognostic factors in lymph node negative breast cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Female; Fluorouracil; Follow-Up Studies; Humans; Lymphatic Metastasis; Methotrexate; Multicenter Studies as Topic; Multivariate Analysis; Plasminogen Activator Inhibitor 1; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Sensitivity and Specificity; Serine Proteinase Inhibitors; Time Factors; Urokinase-Type Plasminogen Activator | 2002 |
Despite some expression of folate receptor alpha in human mesothelioma cells, internalization of methotrexate is predominantly carrier mediated.
Topics: Base Sequence; Biological Transport; Carrier Proteins; Folate Receptors, GPI-Anchored; Gene Expression; Humans; Membrane Transport Proteins; Mesothelioma; Methotrexate; Molecular Sequence Data; Polymerase Chain Reaction; Receptors, Cell Surface; Reduced Folate Carrier Protein; Reference Values; Sensitivity and Specificity; Tumor Cells, Cultured | 2002 |
A cost effectiveness analysis of treatment options for methotrexate-naive rheumatoid arthritis.
Topics: Analysis of Variance; Arthritis, Rheumatoid; Cohort Studies; Cost-Benefit Analysis; Decision Making; Etanercept; Female; Humans; Immunoglobulin G; Isoxazoles; Leflunomide; Male; Methotrexate; Pain Measurement; Probability; Prospective Studies; Receptors, Tumor Necrosis Factor; Sensitivity and Specificity; Sulfasalazine; Treatment Outcome; United States | 2002 |
Urate-oxidase in the prevention and treatment of metabolic complications in patients with B-cell lymphoma and leukemia, treated in the Société Française d'Oncologie Pédiatrique LMB89 protocol.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; France; Humans; Hydrocortisone; Leucovorin; Lymphoma, B-Cell; Male; Methotrexate; Neoplasm Staging; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Survival Rate; Treatment Outcome; Tumor Lysis Syndrome; Urate Oxidase; Vincristine | 2002 |
Kinetic fluorimetric determination of the antineoplastic methotrexate (MTX) in human serum.
Topics: Antimetabolites, Antineoplastic; Humans; Kinetics; Methotrexate; Sensitivity and Specificity; Spectrometry, Fluorescence | 2002 |
Dynamic hepatic scintigraphy in the screening of psoriatic patients for methotrexate-induced hepatotoxicity.
Topics: Adult; Aged; Aged, 80 and over; Biopsy, Needle; Female; Humans; Liver; Liver Cirrhosis; Male; Methotrexate; Middle Aged; Predictive Value of Tests; Psoriasis; Radionuclide Imaging; Sensitivity and Specificity | 1992 |
Tissue polypeptide antigen for monitoring of advanced bladder cancer after MVEC chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cisplatin; Epirubicin; Female; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Peptides; Sensitivity and Specificity; Tissue Polypeptide Antigen; Urinary Bladder Neoplasms; Vinblastine | 1992 |
Sensitivity to change of the health assessment questionnaire (HAQ) and other clinical and health status measures in rheumatoid arthritis: results of short-term clinical trials and observational studies versus long-term observational studies.
Topics: Arthritis, Rheumatoid; Effect Modifier, Epidemiologic; Evaluation Studies as Topic; Female; Health Status; Humans; Kansas; Male; Methotrexate; Middle Aged; Research Design; Sensitivity and Specificity; Surveys and Questionnaires | 1992 |
Assay for expression of methotrexate-resistant dihydrofolate reductase activity in the presence of drug-sensitive enzyme.
Topics: 3T3 Cells; Animals; CHO Cells; Cricetinae; Drug Resistance; Folic Acid Antagonists; Methotrexate; Mice; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase | 1992 |
Precision of the Larsen and the Sharp methods of assessing radiologic change in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Hand; Humans; Male; Methotrexate; Middle Aged; Observer Variation; Radiography; Sensitivity and Specificity; Wrist Joint | 1992 |