Proteins > Acetylcholine-binding protein
Page last updated: 2024-08-07 18:38:48
Acetylcholine-binding protein
[no definition available]
Synonyms
ACh-binding protein;
AchBP
Research
Bioassay Publications (13)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 11 (84.62) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
Compounds (22)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
Exploration of the molecular architecture of the orthosteric binding site in the α4β2 nicotinic acetylcholine receptor with analogs of 3-(dimethylamino)butyl dimethylcarbamate (DMABC) and 1-(pyridin-3-yl)-1,4-diazepane.European journal of medicinal chemistry, , Sep-18, Volume: 102, 2015
Synthesis, pharmacology, and biostructural characterization of novel α4β2 nicotinic acetylcholine receptor agonists.Journal of medicinal chemistry, , Feb-14, Volume: 56, Issue:3, 2013
Structure-based design, synthesis and structure-activity relationships of dibenzosuberyl- and benzoate-substituted tropines as ligands for acetylcholine-binding protein.Bioorganic & medicinal chemistry letters, , Feb-01, Volume: 22, Issue:3, 2012
Insights into the structural determinants required for high-affinity binding of chiral cyclopropane-containing ligands to α4β2-nicotinic acetylcholine receptors: an integrated approach to behaviorally active nicotinic ligands.Journal of medicinal chemistry, , Sep-27, Volume: 55, Issue:18, 2012
Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors.Bioorganic & medicinal chemistry, , Oct-15, Volume: 19, Issue:20, 2011
Unique neonicotinoid binding conformations conferring selective receptor interactions.Journal of agricultural and food chemistry, , Apr-13, Volume: 59, Issue:7, 2011
Interaction kinetic and structural dynamic analysis of ligand binding to acetylcholine-binding protein.Biochemistry, , Sep-21, Volume: 49, Issue:37, 2010
Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptor α7 ligands.Journal of medicinal chemistry, , Oct-14, Volume: 53, Issue:19, 2010
Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis.Journal of medicinal chemistry, , Apr-23, Volume: 52, Issue:8, 2009
Structure-based design, synthesis and structure-activity relationships of dibenzosuberyl- and benzoate-substituted tropines as ligands for acetylcholine-binding protein.Bioorganic & medicinal chemistry letters, , Feb-01, Volume: 22, Issue:3, 2012
Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis.Journal of medicinal chemistry, , Apr-23, Volume: 52, Issue:8, 2009
Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine α4β2 receptors: unique role of halogen bonding revealed.The Journal of biological chemistry, , Feb-03, Volume: 287, Issue:6, 2012
Interaction kinetic and structural dynamic analysis of ligand binding to acetylcholine-binding protein.Biochemistry, , Sep-21, Volume: 49, Issue:37, 2010