Page last updated: 2024-08-07 16:42:31

Histamine H2 receptor

[no definition available]

Synonyms

H2R;
HH2R;
Gastric receptor I

Research

Bioassay Publications (20)

TimeframeStudies on this Protein(%)All Drugs %
pre-19902 (10.00)18.7374
1990's5 (25.00)18.2507
2000's6 (30.00)29.6817
2010's5 (25.00)24.3611
2020's2 (10.00)2.80

Compounds (1313)

Drugs with Potency Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
catecholCavia porcellus (domestic guinea pig)Potency12.589310
chlordeconeCavia porcellus (domestic guinea pig)Potency31.622810
spermidineCavia porcellus (domestic guinea pig)Potency10.905420
spermineCavia porcellus (domestic guinea pig)Potency15.714210
2,4-methanoglutamateCavia porcellus (domestic guinea pig)Potency39.810710
1,5-dihydroxyisoquinolineCavia porcellus (domestic guinea pig)Potency25.118910
my 5445Cavia porcellus (domestic guinea pig)Potency3.981110
1-(3-chlorophenyl)biguanideCavia porcellus (domestic guinea pig)Potency39.810710
1-(3-chlorophenyl)piperazineCavia porcellus (domestic guinea pig)Potency11.035720
1-(2-trifluoromethylphenyl)imidazoleCavia porcellus (domestic guinea pig)Potency15.848910
1-aminocyclohexanecarboxylic acidCavia porcellus (domestic guinea pig)Potency12.589310
1-(1,3-benzodioxol-5-ylcarbonyl)piperidineCavia porcellus (domestic guinea pig)Potency7.943310
17-octadecynoic acidCavia porcellus (domestic guinea pig)Potency12.589310
1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-oneCavia porcellus (domestic guinea pig)Potency39.810710
2-methyl-5-htCavia porcellus (domestic guinea pig)Potency39.810710
2-aminoethoxydiphenyl borateCavia porcellus (domestic guinea pig)Potency19.952610
3,4-dichloroisocoumarinCavia porcellus (domestic guinea pig)Potency15.848910
3-aminobenzamideCavia porcellus (domestic guinea pig)Potency12.589310
4-amino-1,8-naphthalimideCavia porcellus (domestic guinea pig)Potency39.810710
p-chloromercuribenzoic acidCavia porcellus (domestic guinea pig)Potency2.772120
4-diphenylacetoxy-1,1-dimethylpiperidiniumCavia porcellus (domestic guinea pig)Potency39.810710
phenytoinCavia porcellus (domestic guinea pig)Potency39.810710
5,7-dichlorokynurenic acidCavia porcellus (domestic guinea pig)Potency39.810710
5-(n,n-hexamethylene)amilorideCavia porcellus (domestic guinea pig)Potency15.848910
ethylisopropylamilorideCavia porcellus (domestic guinea pig)Potency15.848910
5-(nonyloxy)tryptamineCavia porcellus (domestic guinea pig)Potency20.107120
hydroxyindoleacetic acidCavia porcellus (domestic guinea pig)Potency39.810710
methylbufoteninCavia porcellus (domestic guinea pig)Potency39.810710
6-chloromelatoninCavia porcellus (domestic guinea pig)Potency14.976310
6-hydroxymelatoninCavia porcellus (domestic guinea pig)Potency12.589310
6-nitroso-1,2-benzopyroneCavia porcellus (domestic guinea pig)Potency15.848910
7,8-dihydroxyflavoneCavia porcellus (domestic guinea pig)Potency15.848910
7-chlorokynurenic acidCavia porcellus (domestic guinea pig)Potency31.622810
tacrineCavia porcellus (domestic guinea pig)Potency3.162310
N-(2-aminoethyl)-5-chloro-1-naphthalenesulfonamideCavia porcellus (domestic guinea pig)Potency21.410920
aa 861Cavia porcellus (domestic guinea pig)Potency5.011910
ag 127Cavia porcellus (domestic guinea pig)Potency31.622810
rtki cpdCavia porcellus (domestic guinea pig)Potency15.848910
tyrphostin a23Cavia porcellus (domestic guinea pig)Potency17.984620
tyrphostin 25Cavia porcellus (domestic guinea pig)Potency11.514120
am 251Cavia porcellus (domestic guinea pig)Potency1.995310
am 580Cavia porcellus (domestic guinea pig)Potency15.848910
amiodaroneCavia porcellus (domestic guinea pig)Potency2.012420
amitriptylineCavia porcellus (domestic guinea pig)Potency20.483910
amoxapineCavia porcellus (domestic guinea pig)Potency19.952610
amsacrineCavia porcellus (domestic guinea pig)Potency12.589310
aniracetamCavia porcellus (domestic guinea pig)Potency6.309610
arcaineCavia porcellus (domestic guinea pig)Potency3.981110
astemizoleCavia porcellus (domestic guinea pig)Potency5.745710
aurintricarboxylic acidCavia porcellus (domestic guinea pig)Potency14.762620
benzbromaroneCavia porcellus (domestic guinea pig)Potency0.023810
benzethoniumCavia porcellus (domestic guinea pig)Potency12.589310
benzothiazideCavia porcellus (domestic guinea pig)Potency3.981110
5-methoxypsoralenCavia porcellus (domestic guinea pig)Potency5.011910
bifemelaneCavia porcellus (domestic guinea pig)Potency27.886420
bisacodylCavia porcellus (domestic guinea pig)Potency15.848910
bisbenzimidazoleCavia porcellus (domestic guinea pig)Potency3.981110
bisindolylmaleimide iCavia porcellus (domestic guinea pig)Potency15.848910
bithionolCavia porcellus (domestic guinea pig)Potency5.011910
bml 190Cavia porcellus (domestic guinea pig)Potency39.810710
3-(1-methyl-4-piperidinyl)-1H-indol-5-olCavia porcellus (domestic guinea pig)Potency31.622810
bromperidolCavia porcellus (domestic guinea pig)Potency12.589310
bu 224Cavia porcellus (domestic guinea pig)Potency25.118910
bufexamacCavia porcellus (domestic guinea pig)Potency9.505610
buspironeCavia porcellus (domestic guinea pig)Potency7.943310
butacaineCavia porcellus (domestic guinea pig)Potency19.952610
butambenCavia porcellus (domestic guinea pig)Potency12.589310
candesartan cilexetilCavia porcellus (domestic guinea pig)Potency25.118910
carbetapentaneCavia porcellus (domestic guinea pig)Potency10.000010
carbonyl cyanide m-chlorophenyl hydrazoneCavia porcellus (domestic guinea pig)Potency19.952610
cgs 12066Cavia porcellus (domestic guinea pig)Potency17.559410
cgs 15943Cavia porcellus (domestic guinea pig)Potency31.622810
chelerythrineCavia porcellus (domestic guinea pig)Potency25.186920
chloroxineCavia porcellus (domestic guinea pig)Potency25.118910
chlorpromazineCavia porcellus (domestic guinea pig)Potency11.294710
cilostazolCavia porcellus (domestic guinea pig)Potency39.810710
ciprofloxacinCavia porcellus (domestic guinea pig)Potency12.589310
cleboprideCavia porcellus (domestic guinea pig)Potency7.943310
clemizoleCavia porcellus (domestic guinea pig)Potency13.334720
clobenpropitCavia porcellus (domestic guinea pig)Potency9.146020
clomipramineCavia porcellus (domestic guinea pig)Potency8.856810
clonidineCavia porcellus (domestic guinea pig)Potency7.943310
clotrimazoleCavia porcellus (domestic guinea pig)Potency3.442420
cyclobenzaprineCavia porcellus (domestic guinea pig)Potency18.854110
cyproheptadineCavia porcellus (domestic guinea pig)Potency11.942010
dapsoneCavia porcellus (domestic guinea pig)Potency0.794310
deferiproneCavia porcellus (domestic guinea pig)Potency2.511910
dephostatinCavia porcellus (domestic guinea pig)Potency10.000010
dequaliniumCavia porcellus (domestic guinea pig)Potency4.155210
desipramineCavia porcellus (domestic guinea pig)Potency12.589310
nonivamideCavia porcellus (domestic guinea pig)Potency3.162310
r 59022Cavia porcellus (domestic guinea pig)Potency24.009420
dibucaineCavia porcellus (domestic guinea pig)Potency19.952610
dichlorphenamideCavia porcellus (domestic guinea pig)Potency0.631010
dicyclomineCavia porcellus (domestic guinea pig)Potency17.415120
pentetic acidCavia porcellus (domestic guinea pig)Potency4.152410
dilazepCavia porcellus (domestic guinea pig)Potency13.023820
diphenyleneiodoniumCavia porcellus (domestic guinea pig)Potency4.374720
dipyridamoleCavia porcellus (domestic guinea pig)Potency9.846320
disulfiramCavia porcellus (domestic guinea pig)Potency5.701420
2,3-dimethoxy-1,4-naphthoquinoneCavia porcellus (domestic guinea pig)Potency39.810710
domperidoneCavia porcellus (domestic guinea pig)Potency2.783010
droperidolCavia porcellus (domestic guinea pig)Potency10.000010
dup 697Cavia porcellus (domestic guinea pig)Potency0.794310
dyclonineCavia porcellus (domestic guinea pig)Potency2.511910
ebselenCavia porcellus (domestic guinea pig)Potency0.550320
ellipticineCavia porcellus (domestic guinea pig)Potency19.631220
embelinCavia porcellus (domestic guinea pig)Potency27.720520
emodinCavia porcellus (domestic guinea pig)Potency5.962210
enoxacinCavia porcellus (domestic guinea pig)Potency15.848910
etazolateCavia porcellus (domestic guinea pig)Potency31.622810
ethacrynic acidCavia porcellus (domestic guinea pig)Potency0.631010
ethaverineCavia porcellus (domestic guinea pig)Potency3.981110
ethoxyquinCavia porcellus (domestic guinea pig)Potency7.309220
carbonyl cyanide p-trifluoromethoxyphenylhydrazoneCavia porcellus (domestic guinea pig)Potency15.848910
fenofibrateCavia porcellus (domestic guinea pig)Potency5.011910
flufenamic acidCavia porcellus (domestic guinea pig)Potency18.649120
fluoresciteCavia porcellus (domestic guinea pig)Potency28.183810
fluspirileneCavia porcellus (domestic guinea pig)Potency28.922120
flutamideCavia porcellus (domestic guinea pig)Potency26.200010
fpl 64176Cavia porcellus (domestic guinea pig)Potency2.511910
fusaric acidCavia porcellus (domestic guinea pig)Potency19.952610
gabexateCavia porcellus (domestic guinea pig)Potency12.589310
vanoxerineCavia porcellus (domestic guinea pig)Potency19.990520
gbr 12935Cavia porcellus (domestic guinea pig)Potency21.097520
gemfibrozilCavia porcellus (domestic guinea pig)Potency6.309610
glimepirideCavia porcellus (domestic guinea pig)Potency0.316210
glipizideCavia porcellus (domestic guinea pig)Potency19.783010
glyburideCavia porcellus (domestic guinea pig)Potency4.150210
gossypolCavia porcellus (domestic guinea pig)Potency14.961320
guanfacineCavia porcellus (domestic guinea pig)Potency25.138210
gyki 52466Cavia porcellus (domestic guinea pig)Potency1.258910
haloperidolCavia porcellus (domestic guinea pig)Potency22.609120
hexachloropheneCavia porcellus (domestic guinea pig)Potency10.000010
hexestrolCavia porcellus (domestic guinea pig)Potency19.952610
beta-thujaplicinCavia porcellus (domestic guinea pig)Potency12.589310
tele-methylhistamineCavia porcellus (domestic guinea pig)Potency39.810710
hydrochlorothiazideCavia porcellus (domestic guinea pig)Potency19.783010
hydroflumethiazideCavia porcellus (domestic guinea pig)Potency12.589310
hypericinCavia porcellus (domestic guinea pig)Potency2.511910
ibudilastCavia porcellus (domestic guinea pig)Potency0.631010
phenelzineCavia porcellus (domestic guinea pig)Potency5.079210
imetitCavia porcellus (domestic guinea pig)Potency15.848910
imipramineCavia porcellus (domestic guinea pig)Potency7.943310
amrinoneCavia porcellus (domestic guinea pig)Potency12.589310
indirubin-3'-monoximeCavia porcellus (domestic guinea pig)Potency26.200010
indomethacinCavia porcellus (domestic guinea pig)Potency29.881610
iodoacetamideCavia porcellus (domestic guinea pig)Potency39.810720
isradipineCavia porcellus (domestic guinea pig)Potency19.952610
itraconazoleCavia porcellus (domestic guinea pig)Potency4.466810
1-(2-naphthalenyl)-3-[(phenylmethyl)-propan-2-ylamino]-1-propanoneCavia porcellus (domestic guinea pig)Potency10.424320
1-(2-naphthalenyl)-2-propen-1-oneCavia porcellus (domestic guinea pig)Potency1.995310
jugloneCavia porcellus (domestic guinea pig)Potency3.162310
nsc 664704Cavia porcellus (domestic guinea pig)Potency10.000010
ketanserinCavia porcellus (domestic guinea pig)Potency3.981110
ketotifenCavia porcellus (domestic guinea pig)Potency31.622810
lansoprazoleCavia porcellus (domestic guinea pig)Potency33.934020
beta-lapachoneCavia porcellus (domestic guinea pig)Potency34.898020
leflunomideCavia porcellus (domestic guinea pig)Potency31.622810
qx-314Cavia porcellus (domestic guinea pig)Potency39.810710
lidoflazineCavia porcellus (domestic guinea pig)Potency14.545120
linopirdineCavia porcellus (domestic guinea pig)Potency5.962210
loperamideCavia porcellus (domestic guinea pig)Potency16.765810
loratadineCavia porcellus (domestic guinea pig)Potency9.802320
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-oneCavia porcellus (domestic guinea pig)Potency33.934020
maprotilineCavia porcellus (domestic guinea pig)Potency10.316710
mebendazoleCavia porcellus (domestic guinea pig)Potency1.584910
meclofenamate sodium anhydrousCavia porcellus (domestic guinea pig)Potency7.943310
mefenamic acidCavia porcellus (domestic guinea pig)Potency7.943310
mefloquine hydrochlorideCavia porcellus (domestic guinea pig)Potency25.118910
vitamin k 3Cavia porcellus (domestic guinea pig)Potency6.309610
mesalamineCavia porcellus (domestic guinea pig)Potency12.589310
methapyrileneCavia porcellus (domestic guinea pig)Potency39.810710
methazolamideCavia porcellus (domestic guinea pig)Potency12.589310
methoctramineCavia porcellus (domestic guinea pig)Potency3.162310
nocodazoleCavia porcellus (domestic guinea pig)Potency4.601110
5-methylfurtrethoniumCavia porcellus (domestic guinea pig)Potency31.622810
MeticraneCavia porcellus (domestic guinea pig)Potency12.589310
miconazoleCavia porcellus (domestic guinea pig)Potency2.713620
mirtazapineCavia porcellus (domestic guinea pig)Potency0.050110
mitoxantroneCavia porcellus (domestic guinea pig)Potency7.875810
ml 9Cavia porcellus (domestic guinea pig)Potency18.348020
n(1),n(11)-diethylnorspermineCavia porcellus (domestic guinea pig)Potency19.952610
n(1), n(12)-diethylspermineCavia porcellus (domestic guinea pig)Potency15.848910
n-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamideCavia porcellus (domestic guinea pig)Potency3.201920
n-(6-aminohexyl)-1-naphthalenesulfonamideCavia porcellus (domestic guinea pig)Potency0.199510
fg 7142Cavia porcellus (domestic guinea pig)Potency31.622810
fenamic acidCavia porcellus (domestic guinea pig)Potency15.848910
nialamideCavia porcellus (domestic guinea pig)Potency17.559410
niclosamideCavia porcellus (domestic guinea pig)Potency1.218220
nifedipineCavia porcellus (domestic guinea pig)Potency20.301920
niflumic acidCavia porcellus (domestic guinea pig)Potency31.622810
nilutamideCavia porcellus (domestic guinea pig)Potency28.370810
nimesulideCavia porcellus (domestic guinea pig)Potency6.581210
no 711Cavia porcellus (domestic guinea pig)Potency35.716810
masoprocolCavia porcellus (domestic guinea pig)Potency1.584910
nortriptylineCavia porcellus (domestic guinea pig)Potency18.854110
5-nitro-2-(3-phenylpropylamino)benzoic acidCavia porcellus (domestic guinea pig)Potency12.414520
ns 1619Cavia porcellus (domestic guinea pig)Potency0.794310
o(6)-benzylguanineCavia porcellus (domestic guinea pig)Potency39.810710
omeprazoleCavia porcellus (domestic guinea pig)Potency25.118910
oxatomideCavia porcellus (domestic guinea pig)Potency11.105520
oxethazaineCavia porcellus (domestic guinea pig)Potency3.981110
oxotremorineCavia porcellus (domestic guinea pig)Potency1.497710
papaverineCavia porcellus (domestic guinea pig)Potency26.200010
pd 153035Cavia porcellus (domestic guinea pig)Potency10.286420
pd 169316Cavia porcellus (domestic guinea pig)Potency31.622810
pd 98059Cavia porcellus (domestic guinea pig)Potency31.622810
periciazineCavia porcellus (domestic guinea pig)Potency15.848910
perphenazineCavia porcellus (domestic guinea pig)Potency10.863110
phenazopyridineCavia porcellus (domestic guinea pig)Potency15.848910
phenolsulfonphthaleinCavia porcellus (domestic guinea pig)Potency6.309610
phenylbutazoneCavia porcellus (domestic guinea pig)Potency31.622810
phloretinCavia porcellus (domestic guinea pig)Potency9.566120
phosaloneCavia porcellus (domestic guinea pig)Potency19.952610
phthalylsulfathiazoleCavia porcellus (domestic guinea pig)Potency15.848910
pomiferinCavia porcellus (domestic guinea pig)Potency3.162310
prazosinCavia porcellus (domestic guinea pig)Potency29.021220
proadifenCavia porcellus (domestic guinea pig)Potency11.849520
prochlorperazineCavia porcellus (domestic guinea pig)Potency15.848910
propidiumCavia porcellus (domestic guinea pig)Potency12.589310
protoporphyrin ixCavia porcellus (domestic guinea pig)Potency12.933120
protriptylineCavia porcellus (domestic guinea pig)Potency16.271010
1,2,5,8-tetrahydroxy anthraquinoneCavia porcellus (domestic guinea pig)Potency0.631010
qx-222Cavia porcellus (domestic guinea pig)Potency39.810710
raloxifeneCavia porcellus (domestic guinea pig)Potency12.567410
hydrochlorothiazideCavia porcellus (domestic guinea pig)Potency7.943310
riluzoleCavia porcellus (domestic guinea pig)Potency3.981110
ritanserinCavia porcellus (domestic guinea pig)Potency21.410920
ropiniroleCavia porcellus (domestic guinea pig)Potency39.810710
aurinCavia porcellus (domestic guinea pig)Potency31.622810
sanguinarineCavia porcellus (domestic guinea pig)Potency9.067320
sb 239063Cavia porcellus (domestic guinea pig)Potency7.943310
sb 202190Cavia porcellus (domestic guinea pig)Potency10.907920
scriptaidCavia porcellus (domestic guinea pig)Potency31.622810
sdz 205-557Cavia porcellus (domestic guinea pig)Potency39.810710
sobuzoxaneCavia porcellus (domestic guinea pig)Potency39.810710
spiperoneCavia porcellus (domestic guinea pig)Potency8.971610
fenofibrateCavia porcellus (domestic guinea pig)Potency7.943310
ponalrestatCavia porcellus (domestic guinea pig)Potency15.848910
sulfadimethoxineCavia porcellus (domestic guinea pig)Potency31.622810
sulfamerazineCavia porcellus (domestic guinea pig)Potency0.005010
sulfaphenazoleCavia porcellus (domestic guinea pig)Potency0.224110
sulfaquinoxalineCavia porcellus (domestic guinea pig)Potency3.981110
sulfasalazineCavia porcellus (domestic guinea pig)Potency7.943310
sulfathiazoleCavia porcellus (domestic guinea pig)Potency10.000010
sulfinpyrazoneCavia porcellus (domestic guinea pig)Potency9.020120
sulfisoxazoleCavia porcellus (domestic guinea pig)Potency39.810710
2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]-1-propanolCavia porcellus (domestic guinea pig)Potency3.981110
t0156Cavia porcellus (domestic guinea pig)Potency18.854110
1,4-bis(2-(3,5-dichloropyridyloxy))benzeneCavia porcellus (domestic guinea pig)Potency12.589310
telenzepineCavia porcellus (domestic guinea pig)Potency2.511910
tiaprideCavia porcellus (domestic guinea pig)Potency12.589310
tinoridineCavia porcellus (domestic guinea pig)Potency14.125410
tolnaftateCavia porcellus (domestic guinea pig)Potency1.258910
ici 136,753Cavia porcellus (domestic guinea pig)Potency35.716810
trequinsinCavia porcellus (domestic guinea pig)Potency1.258910
triamtereneCavia porcellus (domestic guinea pig)Potency25.118910
trifluoperazineCavia porcellus (domestic guinea pig)Potency12.589310
trifluperidolCavia porcellus (domestic guinea pig)Potency15.848910
triflupromazineCavia porcellus (domestic guinea pig)Potency8.154810
troglitazoneCavia porcellus (domestic guinea pig)Potency10.000010
tyrphostin a9Cavia porcellus (domestic guinea pig)Potency0.031610
u 99194Cavia porcellus (domestic guinea pig)Potency39.810710
urapidilCavia porcellus (domestic guinea pig)Potency10.730920
6,18,30-trimethyl-3,9,12,15,21,24,27,33,36-nona(propan-2-yl)-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodeconeCavia porcellus (domestic guinea pig)Potency39.810710
w 7Cavia porcellus (domestic guinea pig)Potency9.243320
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazoleCavia porcellus (domestic guinea pig)Potency29.021220
zardaverineCavia porcellus (domestic guinea pig)Potency1.000010
zm 336372Cavia porcellus (domestic guinea pig)Potency15.848910
3,3',5-triiodothyroacetic acidCavia porcellus (domestic guinea pig)Potency5.011910
promazine hydrochlorideCavia porcellus (domestic guinea pig)Potency25.118910
pilocarpineCavia porcellus (domestic guinea pig)Potency15.848910
testosterone propionateCavia porcellus (domestic guinea pig)Potency12.589310
apomorphineCavia porcellus (domestic guinea pig)Potency19.174220
promethazine hydrochlorideCavia porcellus (domestic guinea pig)Potency31.622810
edetic acidCavia porcellus (domestic guinea pig)Potency3.548110
colchicineCavia porcellus (domestic guinea pig)Potency3.162310
ficusinCavia porcellus (domestic guinea pig)Potency7.943310
cycloserineCavia porcellus (domestic guinea pig)Potency39.810710
chlorpromazine hydrochlorideCavia porcellus (domestic guinea pig)Potency15.848910
alizarinCavia porcellus (domestic guinea pig)Potency15.848910
n,n'-diphenyl-4-phenylenediamineCavia porcellus (domestic guinea pig)Potency12.589310
azovioletCavia porcellus (domestic guinea pig)Potency15.848910
iodoformCavia porcellus (domestic guinea pig)Potency31.622810
tetrabromobisphenol aCavia porcellus (domestic guinea pig)Potency20.483910
cyclizineCavia porcellus (domestic guinea pig)Potency7.943310
rotenoneCavia porcellus (domestic guinea pig)Potency31.622810
santowhite powderCavia porcellus (domestic guinea pig)Potency3.162310
dimethisoquinCavia porcellus (domestic guinea pig)Potency12.589310
pseudoephedrineCavia porcellus (domestic guinea pig)Potency0.729020
phenothiazineCavia porcellus (domestic guinea pig)Potency5.011910
thiohexamCavia porcellus (domestic guinea pig)Potency35.481310
fentichlorCavia porcellus (domestic guinea pig)Potency6.578420
1,3-ditolylguanidineCavia porcellus (domestic guinea pig)Potency2.511910
p-tert-butyl catecholCavia porcellus (domestic guinea pig)Potency5.011910
dimethyl-4-phenylenediamineCavia porcellus (domestic guinea pig)Potency12.589310
4-aminodiphenylamineCavia porcellus (domestic guinea pig)Potency2.511910
n-isopropyl-n-phenyl-4-phenylenediamineCavia porcellus (domestic guinea pig)Potency1.000010
n-oxydiethylene-2-benzothiazole sulfenamideCavia porcellus (domestic guinea pig)Potency19.952610
imipramine hydrochlorideCavia porcellus (domestic guinea pig)Potency19.952610
n(1)-acetylphenylhydrazineCavia porcellus (domestic guinea pig)Potency19.952610
chloranilCavia porcellus (domestic guinea pig)Potency12.589310
dianisidineCavia porcellus (domestic guinea pig)Potency19.952610
2-tolidineCavia porcellus (domestic guinea pig)Potency15.848910
cloropheneCavia porcellus (domestic guinea pig)Potency15.848910
dibenzothiazyl disulfideCavia porcellus (domestic guinea pig)Potency10.000010
2-amino-5-nitrothiazoleCavia porcellus (domestic guinea pig)Potency25.118910
suramin sodiumCavia porcellus (domestic guinea pig)Potency3.162310
pyrazolanthroneCavia porcellus (domestic guinea pig)Potency28.370810
3-amino-9-ethylcarbazoleCavia porcellus (domestic guinea pig)Potency15.848910
tetrracaine hydrochlorideCavia porcellus (domestic guinea pig)Potency12.589310
ziramCavia porcellus (domestic guinea pig)Potency10.000010
dextrothyroxineCavia porcellus (domestic guinea pig)Potency6.309610
pentamidine isethionateCavia porcellus (domestic guinea pig)Potency12.589310
norchlorcyclizineCavia porcellus (domestic guinea pig)Potency15.848910
N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamineCavia porcellus (domestic guinea pig)Potency2.760120
lithocholic acidCavia porcellus (domestic guinea pig)Potency22.387210
isocorydineCavia porcellus (domestic guinea pig)Potency12.589310
boldineCavia porcellus (domestic guinea pig)Potency31.622810
rheinCavia porcellus (domestic guinea pig)Potency25.118910
dihydralazineCavia porcellus (domestic guinea pig)Potency39.810710
ninhydrinCavia porcellus (domestic guinea pig)Potency25.118910
hematoxylinCavia porcellus (domestic guinea pig)Potency0.398110
ricinineCavia porcellus (domestic guinea pig)Potency12.589310
acetylsalicylsalicylic acidCavia porcellus (domestic guinea pig)Potency15.848910
chlormethiazoleCavia porcellus (domestic guinea pig)Potency2.511910
myristic acidCavia porcellus (domestic guinea pig)Potency31.622810
gentian violetCavia porcellus (domestic guinea pig)Potency39.810710
eriodictyolCavia porcellus (domestic guinea pig)Potency15.848910
3-hydroxyflavoneCavia porcellus (domestic guinea pig)Potency10.000010
alpha-naphthoflavoneCavia porcellus (domestic guinea pig)Potency7.943310
2-anthramineCavia porcellus (domestic guinea pig)Potency3.981110
benzydamineCavia porcellus (domestic guinea pig)Potency12.589310
n-(1,3-dimethylbutyl)-n'-phenyl-1,4-phenylenediamineCavia porcellus (domestic guinea pig)Potency1.584910
3-methoxycatecholCavia porcellus (domestic guinea pig)Potency1.258910
benzopurpurine 4bCavia porcellus (domestic guinea pig)Potency3.162310
1,1'-methylenedi-2-naphtholCavia porcellus (domestic guinea pig)Potency1.995310
monotributyltin trichlorideCavia porcellus (domestic guinea pig)Potency7.943310
2-amino-4-phenylphenolCavia porcellus (domestic guinea pig)Potency12.589310
sapropterinCavia porcellus (domestic guinea pig)Potency19.952610
fluanisoneCavia porcellus (domestic guinea pig)Potency31.622810
diethylcarbamazine citrateCavia porcellus (domestic guinea pig)Potency10.000010
azaperoneCavia porcellus (domestic guinea pig)Potency13.893120
tetrachloroisophthalonitrileCavia porcellus (domestic guinea pig)Potency31.622810
2-tert-butylhydroquinoneCavia porcellus (domestic guinea pig)Potency7.943310
pimozideCavia porcellus (domestic guinea pig)Potency8.154810
benperidolCavia porcellus (domestic guinea pig)Potency12.589310
1,5-naphthalenediamineCavia porcellus (domestic guinea pig)Potency15.848910
4-(octyloxy)benzoic acidCavia porcellus (domestic guinea pig)Potency3.981110
pontamine sky blueCavia porcellus (domestic guinea pig)Potency12.339620
tranylcypromineCavia porcellus (domestic guinea pig)Potency39.810710
piperacetazineCavia porcellus (domestic guinea pig)Potency12.589310
dexpropranololCavia porcellus (domestic guinea pig)Potency12.780820
alverine citrateCavia porcellus (domestic guinea pig)Potency7.550610
c.i. acid red 114, disodium saltCavia porcellus (domestic guinea pig)Potency3.162310
chloropyramineCavia porcellus (domestic guinea pig)Potency15.848910
pyrithione zincCavia porcellus (domestic guinea pig)Potency15.848910
clemastineCavia porcellus (domestic guinea pig)Potency24.326420
metergolineCavia porcellus (domestic guinea pig)Potency12.924410
n-(cyclohexylthio)phthalimideCavia porcellus (domestic guinea pig)Potency10.000010
daunorubicinCavia porcellus (domestic guinea pig)Potency15.186010
thymolphthaleinCavia porcellus (domestic guinea pig)Potency1.454620
(3R)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-oneCavia porcellus (domestic guinea pig)Potency2.591910
1-(3-chloro-5-benzo[b][1]benzoxepinyl)-4-methylpiperazineCavia porcellus (domestic guinea pig)Potency12.589310
2-n-octyl-4-isothiazolin-3-oneCavia porcellus (domestic guinea pig)Potency2.511910
carbidopaCavia porcellus (domestic guinea pig)Potency22.387210
etofenamateCavia porcellus (domestic guinea pig)Potency12.589310
hc blue no. 2Cavia porcellus (domestic guinea pig)Potency19.952610
propafenone hydrochlorideCavia porcellus (domestic guinea pig)Potency15.848910
ciclopirox olamineCavia porcellus (domestic guinea pig)Potency9.505610
diltiazemCavia porcellus (domestic guinea pig)Potency12.589310
lonidamineCavia porcellus (domestic guinea pig)Potency39.810710
dexibuprofenCavia porcellus (domestic guinea pig)Potency29.094110
nicardipine hydrochlorideCavia porcellus (domestic guinea pig)Potency12.589310
3,3',5,5'-tetramethylbenzidineCavia porcellus (domestic guinea pig)Potency19.952610
torsemideCavia porcellus (domestic guinea pig)Potency12.589310
propiconazoleCavia porcellus (domestic guinea pig)Potency31.622810
ArbaclofenCavia porcellus (domestic guinea pig)Potency15.848910
nicorandilCavia porcellus (domestic guinea pig)Potency1.995310
mitoxantrone hydrochlorideCavia porcellus (domestic guinea pig)Potency3.981110
flupirtineCavia porcellus (domestic guinea pig)Potency20.107120
rimcazoleCavia porcellus (domestic guinea pig)Potency12.589310
enoximoneCavia porcellus (domestic guinea pig)Potency39.810710
azelastine hydrochlorideCavia porcellus (domestic guinea pig)Potency12.589310
atomoxetineCavia porcellus (domestic guinea pig)Potency7.943310
raloxifene hydrochlorideCavia porcellus (domestic guinea pig)Potency10.000010
imazodanCavia porcellus (domestic guinea pig)Potency31.622810
salmeterol xinafoateCavia porcellus (domestic guinea pig)Potency19.952610
eticloprideCavia porcellus (domestic guinea pig)Potency25.118910
ecadotrilCavia porcellus (domestic guinea pig)Potency3.981110
niguldipineCavia porcellus (domestic guinea pig)Potency6.139620
mibefradilCavia porcellus (domestic guinea pig)Potency2.614110
eliprodilCavia porcellus (domestic guinea pig)Potency9.505610
5-AminoacenaphtheneCavia porcellus (domestic guinea pig)Potency15.848910
trichloropheneCavia porcellus (domestic guinea pig)Potency2.511910
ici 63197Cavia porcellus (domestic guinea pig)Potency7.943310
paroxetine hydrochlorideCavia porcellus (domestic guinea pig)Potency25.118910
propranolol hydrochlorideCavia porcellus (domestic guinea pig)Potency15.848910
amodiaquine hydrochlorideCavia porcellus (domestic guinea pig)Potency12.589310
meclizine monohydrochlorideCavia porcellus (domestic guinea pig)Potency12.589310
bts 54 524Cavia porcellus (domestic guinea pig)Potency10.000010
arctigeninCavia porcellus (domestic guinea pig)Potency15.848910
salvinCavia porcellus (domestic guinea pig)Potency0.354810
ginkgolide bCavia porcellus (domestic guinea pig)Potency31.622810
sulconazole, mononitrate, (+-)-isomerCavia porcellus (domestic guinea pig)Potency1.000010
esreboxetineCavia porcellus (domestic guinea pig)Potency22.973720
cgs 9343bCavia porcellus (domestic guinea pig)Potency31.622810
trifluoperazine hydrochlorideCavia porcellus (domestic guinea pig)Potency10.000010
siquilCavia porcellus (domestic guinea pig)Potency10.000010
caramiphenCavia porcellus (domestic guinea pig)Potency31.622810
fluphenazine hydrochlorideCavia porcellus (domestic guinea pig)Potency5.011910
iodophthaleinCavia porcellus (domestic guinea pig)Potency8.912510
harmolCavia porcellus (domestic guinea pig)Potency15.848910
spiramideCavia porcellus (domestic guinea pig)Potency5.011910
1,2-dithiol-3-thioneCavia porcellus (domestic guinea pig)Potency19.952610
2-aminodiphenylamineCavia porcellus (domestic guinea pig)Potency15.848910
clomipramine hydrochlorideCavia porcellus (domestic guinea pig)Potency6.309610
prazosin hydrochlorideCavia porcellus (domestic guinea pig)Potency15.848910
miconazole nitrateCavia porcellus (domestic guinea pig)Potency3.162310
econazole nitrateCavia porcellus (domestic guinea pig)Potency0.794310
rilmenidineCavia porcellus (domestic guinea pig)Potency10.000010
2-chloro-1,4-benzoquinoneCavia porcellus (domestic guinea pig)Potency11.220210
2,2',2''-terpyridineCavia porcellus (domestic guinea pig)Potency2.511910
2-amino-4-tert-butylphenolCavia porcellus (domestic guinea pig)Potency6.309610
aminoquinurideCavia porcellus (domestic guinea pig)Potency5.011910
cromakalimCavia porcellus (domestic guinea pig)Potency39.810710
masoprocolCavia porcellus (domestic guinea pig)Potency6.105920
loxapine succinateCavia porcellus (domestic guinea pig)Potency20.202720
maprotiline hydrochlorideCavia porcellus (domestic guinea pig)Potency11.294710
opipramol hydrochlorideCavia porcellus (domestic guinea pig)Potency12.589310
aceclofenacCavia porcellus (domestic guinea pig)Potency1.584910
hesperetinCavia porcellus (domestic guinea pig)Potency12.924410
magnololCavia porcellus (domestic guinea pig)Potency31.622810
carbobenzoxyvalylphenylalanine aldehydeCavia porcellus (domestic guinea pig)Potency39.810710
paceinCavia porcellus (domestic guinea pig)Potency3.489820
methyl fluorone blackCavia porcellus (domestic guinea pig)Potency12.589310
2-aminobenzenesulfonamideCavia porcellus (domestic guinea pig)Potency3.981110
tetrandrineCavia porcellus (domestic guinea pig)Potency12.589310
5-(n-methyl-n-isobutyl)amilorideCavia porcellus (domestic guinea pig)Potency15.848910
amperozideCavia porcellus (domestic guinea pig)Potency19.952610
pramoxine hydrochlorideCavia porcellus (domestic guinea pig)Potency12.589310
1,2,3,4,5,6-hexabromocyclohexaneCavia porcellus (domestic guinea pig)Potency19.952610
atovaquoneCavia porcellus (domestic guinea pig)Potency1.995310
8-(4-tolylsulfonylamino)quinolineCavia porcellus (domestic guinea pig)Potency12.589310
orphenadrine citrateCavia porcellus (domestic guinea pig)Potency19.952610
6,6'-dithiodinicotinic acidCavia porcellus (domestic guinea pig)Potency1.584910
carbetapentane citrateCavia porcellus (domestic guinea pig)Potency25.118910
mephentermineCavia porcellus (domestic guinea pig)Potency3.162310
prochlorperazine edisylate saltCavia porcellus (domestic guinea pig)Potency3.981110
salsolinolCavia porcellus (domestic guinea pig)Potency15.848910
gliquidoneCavia porcellus (domestic guinea pig)Potency12.589310
sk&f 95282Cavia porcellus (domestic guinea pig)Potency12.924410
thioproperazine mesylateCavia porcellus (domestic guinea pig)Potency12.589310
lekoptinCavia porcellus (domestic guinea pig)Potency8.130620
tarenflurbilCavia porcellus (domestic guinea pig)Potency8.971610
nsc-87877Cavia porcellus (domestic guinea pig)Potency3.162310
azomethine hCavia porcellus (domestic guinea pig)Potency5.074720
oxoglaucineCavia porcellus (domestic guinea pig)Potency39.810710
4-hydroxyantipyrineCavia porcellus (domestic guinea pig)Potency10.000010
s-2-aminoethyl cysteineCavia porcellus (domestic guinea pig)Potency1.258910
zpckCavia porcellus (domestic guinea pig)Potency12.589310
4-methoxydalbergioneCavia porcellus (domestic guinea pig)Potency19.952610
diphyllinCavia porcellus (domestic guinea pig)Potency12.589310
karanjinCavia porcellus (domestic guinea pig)Potency1.000010
episesaminCavia porcellus (domestic guinea pig)Potency3.981110
lobelineCavia porcellus (domestic guinea pig)Potency35.481310
cp-55,940Cavia porcellus (domestic guinea pig)Potency25.118910
vinpocetineCavia porcellus (domestic guinea pig)Potency5.011910
7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-oneCavia porcellus (domestic guinea pig)Potency15.848910
gr 127935Cavia porcellus (domestic guinea pig)Potency6.577320
fr 139317Cavia porcellus (domestic guinea pig)Potency6.309610
sr 95531Cavia porcellus (domestic guinea pig)Potency3.162310
fk 888Cavia porcellus (domestic guinea pig)Potency22.387210
dihydrocapsaicinCavia porcellus (domestic guinea pig)Potency6.256010
6-chloro-2-(1-piperazinyl)pyrazineCavia porcellus (domestic guinea pig)Potency1.995310
lasolvanCavia porcellus (domestic guinea pig)Potency12.589310
5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indoleCavia porcellus (domestic guinea pig)Potency25.118910
tesmilifeneCavia porcellus (domestic guinea pig)Potency13.509320
benzamilCavia porcellus (domestic guinea pig)Potency17.900810
carboxyamido-triazoleCavia porcellus (domestic guinea pig)Potency0.501210
3',4'-dichlorobenzamilCavia porcellus (domestic guinea pig)Potency15.848910
1-(carboxymethylthio)tetradecaneCavia porcellus (domestic guinea pig)Potency36.535520
selenocystamineCavia porcellus (domestic guinea pig)Potency0.823720
zk 93426Cavia porcellus (domestic guinea pig)Potency35.481310
2-iodomelatoninCavia porcellus (domestic guinea pig)Potency39.810710
n-(phenylthio)-epsilon-caprolactamCavia porcellus (domestic guinea pig)Potency19.952610
bw 373u86Cavia porcellus (domestic guinea pig)Potency3.981110
gr 113808Cavia porcellus (domestic guinea pig)Potency12.339620
ah 6809Cavia porcellus (domestic guinea pig)Potency31.622810
sb 204070aCavia porcellus (domestic guinea pig)Potency39.810710
l 655240Cavia porcellus (domestic guinea pig)Potency16.225020
luzindoleCavia porcellus (domestic guinea pig)Potency15.848910
5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamideCavia porcellus (domestic guinea pig)Potency0.631010
a 68930Cavia porcellus (domestic guinea pig)Potency6.309610
profenamine hydrochlorideCavia porcellus (domestic guinea pig)Potency12.589310
2-palmitoylglycerolCavia porcellus (domestic guinea pig)Potency15.848910
gefitinibCavia porcellus (domestic guinea pig)Potency19.952610
1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidineCavia porcellus (domestic guinea pig)Potency31.622810
cp 93129Cavia porcellus (domestic guinea pig)Potency7.943310
glabraninCavia porcellus (domestic guinea pig)Potency3.162310
desloratadineCavia porcellus (domestic guinea pig)Potency25.118910
n-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamideCavia porcellus (domestic guinea pig)Potency5.011910
2,2'-pyridylisatogen tosylateCavia porcellus (domestic guinea pig)Potency31.622810
w 7Cavia porcellus (domestic guinea pig)Potency15.848910
indatralineCavia porcellus (domestic guinea pig)Potency12.589310
bd 1008Cavia porcellus (domestic guinea pig)Potency12.589310
pre 084Cavia porcellus (domestic guinea pig)Potency12.924410
ro 19-4603Cavia porcellus (domestic guinea pig)Potency5.011910
4-iodo-n-piperidinoethylbenzamideCavia porcellus (domestic guinea pig)Potency29.021220
vb 20b7Cavia porcellus (domestic guinea pig)Potency7.943310
gr 55562Cavia porcellus (domestic guinea pig)Potency10.000010
sr 2640Cavia porcellus (domestic guinea pig)Potency19.783010
n-butyl beta-carboline-3-carboxylateCavia porcellus (domestic guinea pig)Potency7.943310
1,3-dipropyl-8-phenylxanthineCavia porcellus (domestic guinea pig)Potency1.584910
2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazoleCavia porcellus (domestic guinea pig)Potency3.981110
l 694247Cavia porcellus (domestic guinea pig)Potency31.622810
n,n-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamideCavia porcellus (domestic guinea pig)Potency5.011910
4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazineCavia porcellus (domestic guinea pig)Potency31.622810
3,5-bis(trifluoromethyl)benzyl n-acetyltryptophanCavia porcellus (domestic guinea pig)Potency12.589310
l 733060Cavia porcellus (domestic guinea pig)Potency4.009520
n-(n-benzylpiperidin-4-yl)-4-iodobenzamideCavia porcellus (domestic guinea pig)Potency39.810710
l 741742Cavia porcellus (domestic guinea pig)Potency15.848910
8-cyclopentyl-3-(3-((4-(fluorosulfonyl)benzoyl)oxy)propyl)-1-propylxanthineCavia porcellus (domestic guinea pig)Potency3.162310
isoteolinCavia porcellus (domestic guinea pig)Potency25.118910
l 741626Cavia porcellus (domestic guinea pig)Potency27.886420
bp 554Cavia porcellus (domestic guinea pig)Potency12.589320
bts 54 505Cavia porcellus (domestic guinea pig)Potency10.000010
cd 437Cavia porcellus (domestic guinea pig)Potency7.943310
5,5,7,12,12,14-hexamethyl-1,4,8,11-tetrazacyclotetradecaneCavia porcellus (domestic guinea pig)Potency7.943310
3',4'-dihydroxyflavoneCavia porcellus (domestic guinea pig)Potency10.000010
3,3',4'-trihydroxyflavoneCavia porcellus (domestic guinea pig)Potency24.009420
escitalopramCavia porcellus (domestic guinea pig)Potency10.411820
8-(methylsulfonylamino)quinolineCavia porcellus (domestic guinea pig)Potency15.848910
n,n-dipropylcarboxamidotryptamineCavia porcellus (domestic guinea pig)Potency39.810710
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acidCavia porcellus (domestic guinea pig)Potency10.000010
isradipine, (s)-isomerCavia porcellus (domestic guinea pig)Potency0.794310
ag 3-5Cavia porcellus (domestic guinea pig)Potency1.000010
corbadrineCavia porcellus (domestic guinea pig)Potency19.952610
2-phenyl-1,2-benzisothiazol-3-(2h)-oneCavia porcellus (domestic guinea pig)Potency1.258910
2-[carboxymethyl-[2-(2,6-diethylanilino)-2-oxoethyl]amino]acetic acidCavia porcellus (domestic guinea pig)Potency1.995310
sb 203580Cavia porcellus (domestic guinea pig)Potency11.244720
nbi 27914Cavia porcellus (domestic guinea pig)Potency31.622810
sb 216763Cavia porcellus (domestic guinea pig)Potency20.811410
zm 241385Cavia porcellus (domestic guinea pig)Potency39.810710
chrysene-1,4-dioneCavia porcellus (domestic guinea pig)Potency1.760120
rs 67333Cavia porcellus (domestic guinea pig)Potency25.118910
hexestrolCavia porcellus (domestic guinea pig)Potency7.007120
fr 122047Cavia porcellus (domestic guinea pig)Potency24.620720
hydrastineCavia porcellus (domestic guinea pig)Potency25.118910
benfluorex hydrochlorideCavia porcellus (domestic guinea pig)Potency3.981110
ci 966Cavia porcellus (domestic guinea pig)Potency2.511910
roxindoleCavia porcellus (domestic guinea pig)Potency19.749120
pimaric acidCavia porcellus (domestic guinea pig)Potency6.309610
brazilinCavia porcellus (domestic guinea pig)Potency1.995310
carbamothioic acid S-[2-(2-methoxyanilino)-2-oxoethyl] esterCavia porcellus (domestic guinea pig)Potency3.981110
colchiceineCavia porcellus (domestic guinea pig)Potency15.848910
gant58Cavia porcellus (domestic guinea pig)Potency1.995310
nsc 95397Cavia porcellus (domestic guinea pig)Potency7.099320
1-amino-9,10-dioxo-4-(3-sulfamoylanilino)anthracene-2-sulfonic acidCavia porcellus (domestic guinea pig)Potency3.162320
berbamineCavia porcellus (domestic guinea pig)Potency15.848910
noscapineCavia porcellus (domestic guinea pig)Potency0.125910
N-butyl-1H-benzimidazol-2-amineCavia porcellus (domestic guinea pig)Potency19.952610
hematoxylinCavia porcellus (domestic guinea pig)Potency3.761910
2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-oneCavia porcellus (domestic guinea pig)Potency0.063110
2-(1-adamantyl)imidazoleCavia porcellus (domestic guinea pig)Potency25.118910
5-(1,3-benzodioxol-5-yl)-N-(2,4-dimethylphenyl)-1,3,4-oxadiazol-2-amineCavia porcellus (domestic guinea pig)Potency7.943310
2,5-bis(5-hydroxymethyl-2-thienyl)furanCavia porcellus (domestic guinea pig)Potency17.782810
nsc668394Cavia porcellus (domestic guinea pig)Potency1.584910
nsc681152Cavia porcellus (domestic guinea pig)Potency7.943310
mrs 1220Cavia porcellus (domestic guinea pig)Potency3.162310
gant 61Cavia porcellus (domestic guinea pig)Potency3.162310
2H-pyrazolo[4,3-b]quinoxalin-3-amineCavia porcellus (domestic guinea pig)Potency1.995310
carnosineCavia porcellus (domestic guinea pig)Potency39.810710
naringeninCavia porcellus (domestic guinea pig)Potency12.589310
tosylphenylalanyl chloromethyl ketoneCavia porcellus (domestic guinea pig)Potency19.952610
amiodarone hydrochlorideCavia porcellus (domestic guinea pig)Potency15.848910
dicyclomine hydrochlorideCavia porcellus (domestic guinea pig)Potency15.848910
nortriptyline hydrochlorideCavia porcellus (domestic guinea pig)Potency12.589310
raubasineCavia porcellus (domestic guinea pig)Potency10.000010
hydrastine hydrochloride, (s-(r*,s*))-isomerCavia porcellus (domestic guinea pig)Potency6.610510
(-)-usnic acidCavia porcellus (domestic guinea pig)Potency0.006310
N-(3-Benzooxazol-2-yl-4-hydroxy-phenyl)-2-p-tolyloxyacetamideCavia porcellus (domestic guinea pig)Potency25.118910
L-isoprenalineCavia porcellus (domestic guinea pig)Potency19.952610
sb 221284Cavia porcellus (domestic guinea pig)Potency0.006310
sb 228357Cavia porcellus (domestic guinea pig)Potency5.397210
arachidonic acidCavia porcellus (domestic guinea pig)Potency31.622810
resveratrolCavia porcellus (domestic guinea pig)Potency19.952610
alpha-methyl-4-carboxyphenylglycineCavia porcellus (domestic guinea pig)Potency19.952610
5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diolCavia porcellus (domestic guinea pig)Potency4.638520
(S)-ATPACavia porcellus (domestic guinea pig)Potency31.622810
gw 3965Cavia porcellus (domestic guinea pig)Potency31.622810
rolipramCavia porcellus (domestic guinea pig)Potency39.810710
diethylstilbestrolCavia porcellus (domestic guinea pig)Potency15.848910
ketoconazoleCavia porcellus (domestic guinea pig)Potency10.077420
purvalanol aCavia porcellus (domestic guinea pig)Potency18.406620
isotetrandrineCavia porcellus (domestic guinea pig)Potency10.000010
6-methyl-2-[(4-nitrophenyl)methylthio]-1H-benzimidazoleCavia porcellus (domestic guinea pig)Potency31.622810
dipyroneCavia porcellus (domestic guinea pig)Potency18.854110
4-(4-chloro-2-methylphenoxy)-n-hydroxybutanamideCavia porcellus (domestic guinea pig)Potency15.848910
bd 1063Cavia porcellus (domestic guinea pig)Potency15.848910
2-[[(6-bromo-1H-benzimidazol-2-yl)thio]methyl]-1-methylbenzimidazoleCavia porcellus (domestic guinea pig)Potency1.995310
4-chloro-N-(4-chloro-2,5-dimethoxyphenyl)-5-dithiazolimineCavia porcellus (domestic guinea pig)Potency25.118910
tolfenamic acidCavia porcellus (domestic guinea pig)Potency3.162310
isoliquiritigeninCavia porcellus (domestic guinea pig)Potency7.943310
gw9662Cavia porcellus (domestic guinea pig)Potency6.309610
1-[4-[4-[(4-methylphenyl)methylamino]phenyl]-1-piperazinyl]ethanoneCavia porcellus (domestic guinea pig)Potency10.000010
2-[3-[3-[3-(1-imidazolyl)propyl]-4-oxo-2-quinazolinyl]propyl]isoindole-1,3-dioneCavia porcellus (domestic guinea pig)Potency25.118910
1-(1-benzimidazolyl)-3-(1-cyclohex-3-enylmethoxy)-2-propanolCavia porcellus (domestic guinea pig)Potency25.118910
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[[1-(3,4-dimethoxyphenyl)-5-tetrazolyl]thio]acetamideCavia porcellus (domestic guinea pig)Potency39.810710
N-[4-chloro-2-[(2,4-dimethoxyanilino)-oxomethyl]phenyl]-2-furancarboxamideCavia porcellus (domestic guinea pig)Potency31.622810
7-[2-hydroxy-3-(2-methylphenoxy)propyl]-3-methyl-8-(propan-2-ylthio)purine-2,6-dioneCavia porcellus (domestic guinea pig)Potency39.810710
2-(1,3-benzodioxol-5-ylamino)-N-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetamideCavia porcellus (domestic guinea pig)Potency39.810710
5-(4-propylcyclohexyl)-3-(3-pyridinyl)-1,2,4-oxadiazoleCavia porcellus (domestic guinea pig)Potency31.622810
4-[2-[1-(4-methoxyphenyl)sulfonyl-2-benzimidazolyl]ethyl]morpholineCavia porcellus (domestic guinea pig)Potency19.952610
2-(1-benzimidazolylmethyl)-5-[(4-chlorophenyl)methylthio]-1,3,4-oxadiazoleCavia porcellus (domestic guinea pig)Potency25.118910
N-[1-methyl-5-(4-methylphenyl)-2-imidazolyl]-4-oxo-4-(1-piperidinyl)butanamideCavia porcellus (domestic guinea pig)Potency39.810710
1-[(7,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-[(1-ethyl-2-pyrrolidinyl)methyl]-3-(2-methoxyphenyl)ureaCavia porcellus (domestic guinea pig)Potency15.848910
N-(1,3-benzodioxol-5-yl)-2-[2-(3-chloro-4-methylanilino)-2-oxoethyl]sulfinylacetamideCavia porcellus (domestic guinea pig)Potency19.952610
5-(1,3-benzodioxol-5-yl)-1-methyl-2-imidazolamineCavia porcellus (domestic guinea pig)Potency25.118910
haplamineCavia porcellus (domestic guinea pig)Potency25.118910
1-[4-[4-[(phenylmethyl)amino]phenyl]-1-piperazinyl]ethanoneCavia porcellus (domestic guinea pig)Potency15.848910
N-[1-(2-methoxyphenyl)-5-benzimidazolyl]benzenesulfonamideCavia porcellus (domestic guinea pig)Potency25.118910
N-[1-[4-(4-methylphenyl)-2-thiazolyl]-4-piperidinyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideCavia porcellus (domestic guinea pig)Potency39.810710
6-chloro-2-[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-piperidinyl]-1H-benzimidazoleCavia porcellus (domestic guinea pig)Potency19.952610
6-amino-4-(2,5-dimethoxyphenyl)-3-methyl-1-(4-methylphenyl)-4H-pyrano[2,3-c]pyrazole-5-carbonitrileCavia porcellus (domestic guinea pig)Potency1.995310
N4-(2-furanylmethyl)-N2-(3-methylphenyl)-6-(4-morpholinyl)-1,3,5-triazine-2,4-diamineCavia porcellus (domestic guinea pig)Potency25.118910
1-[3-(dimethylamino)propyl]-1-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-3-(phenylmethyl)ureaCavia porcellus (domestic guinea pig)Potency19.952610
2-[(4-fluorophenoxy)methyl]-5-[3-(1-imidazolyl)propylamino]-4-oxazolecarbonitrileCavia porcellus (domestic guinea pig)Potency19.952610
N-(5-methoxy-1,3-benzothiazol-2-yl)-3-methylbutanamideCavia porcellus (domestic guinea pig)Potency2.511910
N-[2-[2-[2-(4-methoxyanilino)-2-oxoethyl]-5-tetrazolyl]phenyl]-2-furancarboxamideCavia porcellus (domestic guinea pig)Potency19.952610
3-(4-methoxyphenyl)-8-(6-methyl-2-phenyl-4-pyrimidinyl)-8-azabicyclo[3.2.1]octan-3-olCavia porcellus (domestic guinea pig)Potency25.118910
xe 991, anthracenoneCavia porcellus (domestic guinea pig)Potency19.952610
1-cyclohexyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-amineCavia porcellus (domestic guinea pig)Potency25.118910
6,6,7-trimethyl-1-(4-morpholinyl)-3-(phenylmethylthio)-5,8-dihydro-2,7-naphthyridine-4-carbonitrileCavia porcellus (domestic guinea pig)Potency3.162310
LSM-16947Cavia porcellus (domestic guinea pig)Potency19.952610
5-ethyl-4,6-dimethyl-2-sulfanylidene-1H-pyridine-3-carbonitrileCavia porcellus (domestic guinea pig)Potency31.622810
3-(4-butyl-3,5-dimethyl-1-pyrazolyl)-5-methyl-[1,2,4]triazino[5,6-b]indoleCavia porcellus (domestic guinea pig)Potency7.943310
5-bromo-3-[[2-(4-cyclohexyl-1-piperazinyl)-1-oxoethyl]amino]-1H-indole-2-carboxylic acid methyl esterCavia porcellus (domestic guinea pig)Potency25.118910
(1-methyl-2-imidazolyl)-(4-phenylmethoxyphenyl)methanolCavia porcellus (domestic guinea pig)Potency19.952610
4-chlorobenzoic acid 2-(2-amino-3-cyano-1-pyrrolo[3,2-b]quinoxalinyl)ethyl esterCavia porcellus (domestic guinea pig)Potency39.810710
2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-(8-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)ethanoneCavia porcellus (domestic guinea pig)Potency3.162310
2-(2-oxo-3H-1,4-benzoxazin-4-yl)acetic acid [2-(3-bromo-4-methoxyphenyl)-2-oxoethyl] esterCavia porcellus (domestic guinea pig)Potency6.309610
4-[1-(4-hydroxyphenyl)ethenyl]phenolCavia porcellus (domestic guinea pig)Potency25.118910
2-(2,4-dioxo-3-phenyl-5-thiazolidinyl)-N-phenylacetamideCavia porcellus (domestic guinea pig)Potency6.309610
2-ethyl-1-[(2-methoxyphenyl)methyl]benzimidazoleCavia porcellus (domestic guinea pig)Potency15.848910
2-(butan-2-ylamino)-N-[4-[5-[[2-(butan-2-ylamino)-1-oxoethyl]amino]-1,3-benzoxazol-2-yl]phenyl]acetamideCavia porcellus (domestic guinea pig)Potency12.589310
2-[(2-fluorophenoxy)methyl]-5-[3-(1-imidazolyl)propylamino]-4-oxazolecarbonitrileCavia porcellus (domestic guinea pig)Potency39.810710
5-bromo-3-[[2-(4-methyl-1-piperazinyl)-1-oxoethyl]amino]-2-benzofurancarboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency15.848910
2-[2-[(1-phenyl-4-pyrazolo[3,4-d]pyrimidinyl)amino]ethoxy]ethanolCavia porcellus (domestic guinea pig)Potency15.848910
1-(3,5-dichlorophenyl)-3-(N-hydroxyanilino)pyrrolidine-2,5-dioneCavia porcellus (domestic guinea pig)Potency15.848910
4-(cyclohexylamino)-2-(3,5-dimethyl-1-pyrazolyl)-5-pyrimidinecarboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency6.309610
1-(3,4-dichlorophenyl)-2-[[4-(2-furanylmethyl)-5-(3-pyridinyl)-1,2,4-triazol-3-yl]thio]ethanoneCavia porcellus (domestic guinea pig)Potency15.848910
3-methyl-N-(1-propyl-3-pyrazolo[3,4-b]quinolinyl)butanamideCavia porcellus (domestic guinea pig)Potency39.810710
6-[(2,4-dichlorophenoxy)methyl]-3-(2-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoleCavia porcellus (domestic guinea pig)Potency19.952610
4-[4-(1H-benzimidazol-2-ylmethyl)-1-piperazinyl]benzofuro[3,2-d]pyrimidineCavia porcellus (domestic guinea pig)Potency15.848910
4-(1H-benzimidazol-2-ylmethylthio)-2-methylbenzofuro[3,2-d]pyrimidineCavia porcellus (domestic guinea pig)Potency25.118910
LSM-26505Cavia porcellus (domestic guinea pig)Potency25.118910
2-[4-[(4-chlorophenyl)methoxy]phenyl]-5-[3-(1-imidazolyl)propylamino]-4-oxazolecarbonitrileCavia porcellus (domestic guinea pig)Potency3.162310
3-[[2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-oxoethyl]amino]-1H-indole-2-carboxylic acid methyl esterCavia porcellus (domestic guinea pig)Potency19.952610
3-(3-benzoyl-6-chloro-4,5-dihydroxy-7-benzofuranyl)pentane-2,4-dioneCavia porcellus (domestic guinea pig)Potency1.000010
1-[(4-fluorophenyl)methyl]-3-(2-furanylmethyl)-4-imino-6,6-dimethyl-5,8-dihydropyrano[2,3]thieno[2,4-b]pyrimidin-2-oneCavia porcellus (domestic guinea pig)Potency31.622810
Glyceryl lactopalmitateCavia porcellus (domestic guinea pig)Potency31.622810
3-[[2-(3,5-dimethyl-1-pyrazolyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl]amino]-1-propanolCavia porcellus (domestic guinea pig)Potency3.981110
3-(4-methoxyphenyl)-6-[(4-methylphenoxy)methyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoleCavia porcellus (domestic guinea pig)Potency39.810710
N5,N5-dimethyl-2,1,3-benzoxadiazole-4,5-diamineCavia porcellus (domestic guinea pig)Potency15.848910
7-methyl-3-(3-methylbutylamino)-1-(1-pyrrolidinyl)-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrileCavia porcellus (domestic guinea pig)Potency7.943310
3-[(3aR,6aS)-6'-chloro-5-(4-chlorophenyl)-7'-methyl-2',4,6-trioxo-1-spiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]yl]propanamideCavia porcellus (domestic guinea pig)Potency31.622810
7-(3,4-dimethoxyphenyl)-4-methyl-2-[4-(phenylmethyl)-1-piperazinyl]-7,8-dihydro-6H-quinazolin-5-oneCavia porcellus (domestic guinea pig)Potency15.848910
N-[1-methyl-2-[2-(4-phenyl-1-piperazinyl)ethyl]-5-benzimidazolyl]-2-furancarboxamideCavia porcellus (domestic guinea pig)Potency12.589310
2-methyl-3-phenyl-5-propyl-7-[4-(2-pyridinyl)-1-piperazinyl]pyrazolo[1,5-a]pyrimidineCavia porcellus (domestic guinea pig)Potency25.118910
(3aR,6aS)-3-(3,4-dimethoxyphenyl)-5-(2,4-dimethylphenyl)-3a,6a-dihydropyrrolo[3,4-d]isoxazole-4,6-dioneCavia porcellus (domestic guinea pig)Potency12.589310
3-(1,3-benzodioxol-5-ylmethyl)-4,10-dihydro-2H-[1,3,5]triazino[1,2-a]benzimidazoleCavia porcellus (domestic guinea pig)Potency19.952610
N2-(4-fluorophenyl)-6-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-1,3,5-triazine-2,4-diamineCavia porcellus (domestic guinea pig)Potency3.981110
6-[[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]methyl]-N2-(3-methylphenyl)-1,3,5-triazine-2,4-diamineCavia porcellus (domestic guinea pig)Potency2.511910
2-methoxy-1-(1-methyl-2-benzimidazolyl)-1-phenylethanamineCavia porcellus (domestic guinea pig)Potency10.000010
2-[[[5-(3-chlorophenyl)-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]thio]methyl]-1H-benzimidazoleCavia porcellus (domestic guinea pig)Potency10.000010
3-(4-methoxyphenyl)-2-(4-methyl-1-piperazinyl)-6,7,8,9-tetrahydro-5H-cyclohepta[2,3]thieno[2,4-b]pyrimidin-4-oneCavia porcellus (domestic guinea pig)Potency3.162310
chlorprothixeneCavia porcellus (domestic guinea pig)Potency12.589310
dienestrolCavia porcellus (domestic guinea pig)Potency15.848910
doxepin hydrochlorideCavia porcellus (domestic guinea pig)Potency15.848910
ag-213Cavia porcellus (domestic guinea pig)Potency21.539020
3,3',4,5'-tetrahydroxystilbeneCavia porcellus (domestic guinea pig)Potency4.466810
7,8,3'-trihydroxyflavoneCavia porcellus (domestic guinea pig)Potency1.584910
sch-202676Cavia porcellus (domestic guinea pig)Potency1.597220
procaterolCavia porcellus (domestic guinea pig)Potency12.589310
5-(4-methoxyphenyl)-1,2-dihydro-1,2,4-triazole-3-thioneCavia porcellus (domestic guinea pig)Potency39.810710
N-[(2-phenylethylamino)-sulfanylidenemethyl]benzamideCavia porcellus (domestic guinea pig)Potency12.589310
captaxCavia porcellus (domestic guinea pig)Potency33.552010
2-[(3-methyl-6-oxo-7,8,9,10-tetrahydrobenzo[c][1]benzopyran-1-yl)oxy]acetic acid propan-2-yl esterCavia porcellus (domestic guinea pig)Potency0.199510
2-(1H-benzimidazol-2-ylthio)-1-(2,3-dimethyl-1-indolyl)ethanoneCavia porcellus (domestic guinea pig)Potency25.118910
4,6-dimethyl-2-[[2-oxo-2-(1-piperidinyl)ethyl]thio]-3-pyridinecarbonitrileCavia porcellus (domestic guinea pig)Potency39.810710
4-chloro-N-(3,4,5-trimethoxyphenyl)-5-dithiazolimineCavia porcellus (domestic guinea pig)Potency25.118910
dexchlorpheniramineCavia porcellus (domestic guinea pig)Potency19.917910
phenylthiazolylthioureaCavia porcellus (domestic guinea pig)Potency18.311120
1-ethyl-2-[[(1-methyl-2-benzimidazolyl)thio]methyl]benzimidazoleCavia porcellus (domestic guinea pig)Potency3.981110
2-amino-4-(2-furanyl)-3-thiophenecarboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency15.848910
2-(2,3-dihydroindol-1-yl)-N,N-dimethylethanamineCavia porcellus (domestic guinea pig)Potency25.118910
2-[[3-[(2-hydroxyphenyl)methyl]-1,3-diazinan-1-yl]methyl]phenolCavia porcellus (domestic guinea pig)Potency12.589310
N2,N4-ditert-butyl-6-hydrazinyl-1,3,5-triazine-2,4-diamineCavia porcellus (domestic guinea pig)Potency7.943310
4-(benzenesulfonyl)-5-(ethylthio)-2-phenyloxazoleCavia porcellus (domestic guinea pig)Potency31.622810
cid755673Cavia porcellus (domestic guinea pig)Potency1.000010
4-phenyl-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamineCavia porcellus (domestic guinea pig)Potency31.622810
1-[(4-phenyl-1-piperazinyl)methyl]-2-naphthalenolCavia porcellus (domestic guinea pig)Potency39.810710
2-[[2-(5,6-dimethyl-1-benzimidazolyl)-1-oxoethyl]amino]benzoic acid methyl esterCavia porcellus (domestic guinea pig)Potency10.000010
N-(1-ethyl-5-benzimidazolyl)-4-methylbenzenesulfonamideCavia porcellus (domestic guinea pig)Potency39.810710
4-methyl-N-[1-[2-(1-pyrrolidinyl)ethyl]-2-benzimidazolyl]benzamideCavia porcellus (domestic guinea pig)Potency7.943310
4-tert-butyl-N-[2-(2-methoxyphenyl)ethyl]-1-cyclohexanamineCavia porcellus (domestic guinea pig)Potency25.118910
2-methoxy-4-[[2-(methylthio)anilino]methyl]phenolCavia porcellus (domestic guinea pig)Potency31.622810
1-[[3-(4-chlorophenoxy)phenyl]methyl]-4-ethylpiperazineCavia porcellus (domestic guinea pig)Potency15.848910
9-ethyl-1,2,4,5-tetrazaspiro[5.5]undecane-3-thioneCavia porcellus (domestic guinea pig)Potency7.943310
1-(1,3-benzodioxol-5-ylmethyl)-3-(2,5-dimethylphenyl)thioureaCavia porcellus (domestic guinea pig)Potency25.118910
8-methyl-2-phenyl-1,2,4-triazaspiro[4.5]decane-3-thioneCavia porcellus (domestic guinea pig)Potency6.309610
N-[[(2,4-dimethyl-8-quinolinyl)amino]-sulfanylidenemethyl]-4-methylbenzamideCavia porcellus (domestic guinea pig)Potency25.118910
N-methyl-2-(4-methylphenyl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amineCavia porcellus (domestic guinea pig)Potency31.622810
6-[amino(methyl)amino]-N2,N4-diethyl-1,3,5-triazine-2,4-diamineCavia porcellus (domestic guinea pig)Potency3.162310
4-[(4-chlorophenyl)thio]-5-methyl-2-phenyl-1H-pyrazol-3-oneCavia porcellus (domestic guinea pig)Potency10.000010
N-(2-furanylmethyl)-1-(4-methoxyphenyl)-5-benzimidazolamineCavia porcellus (domestic guinea pig)Potency12.589310
N-[3,4-dihydro-2H-quinolin-1-yl(sulfanylidene)methyl]-2-(3-methylphenoxy)acetamideCavia porcellus (domestic guinea pig)Potency19.952610
3-(1,3-benzodioxol-5-yl)-4-(2,5-dimethylphenyl)-1H-1,2,4-triazole-5-thioneCavia porcellus (domestic guinea pig)Potency19.952610
4-(3-methylphenyl)-3-(5-propan-2-yl-3-thiophenyl)-1H-1,2,4-triazole-5-thioneCavia porcellus (domestic guinea pig)Potency7.943310
4-(phenylmethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thioneCavia porcellus (domestic guinea pig)Potency12.589310
1-[2-(2-chlorophenoxy)ethyl]benzimidazoleCavia porcellus (domestic guinea pig)Potency12.589310
5-[2-(6-hydroxy-3-methyl-2-benzofuranyl)-2-oxoethyl]-2-furancarboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency25.118910
1-ethyl-N-[(4-methoxyphenyl)methyl]-5-benzimidazolamineCavia porcellus (domestic guinea pig)Potency31.622810
4-methoxy-2-[3-(4-methoxyphenyl)-5-methyl-1H-pyrazol-4-yl]phenolCavia porcellus (domestic guinea pig)Potency12.589310
3-bromo-N-[(tert-butylamino)-sulfanylidenemethyl]-4-methoxybenzamideCavia porcellus (domestic guinea pig)Potency15.848910
1-[(3-methylphenyl)methyl]benzimidazoleCavia porcellus (domestic guinea pig)Potency31.622810
lupitidineCavia porcellus (domestic guinea pig)Potency31.622810
1-(cycloheptylideneamino)-3-(4-fluorophenyl)thioureaCavia porcellus (domestic guinea pig)Potency39.810710
4-methoxy-N-[[(phenylmethyl)amino]-sulfanylidenemethyl]benzamideCavia porcellus (domestic guinea pig)Potency10.000010
N-(2-ethoxyphenyl)-1H-benzimidazol-2-amineCavia porcellus (domestic guinea pig)Potency1.995310
2-(4-methyl-1-piperazinyl)-6-phenyl-4-pyrimidinecarbonitrileCavia porcellus (domestic guinea pig)Potency39.810710
thiothixeneCavia porcellus (domestic guinea pig)Potency17.488210
6-methoxy-3-[(3-methylanilino)methyl]-1H-quinolin-2-oneCavia porcellus (domestic guinea pig)Potency39.810710
curcuminCavia porcellus (domestic guinea pig)Potency7.943310
3-chloro-4-[(1-ethyl-2-benzimidazolyl)thio]anilineCavia porcellus (domestic guinea pig)Potency31.622810
1-[[(2-chlorophenyl)-oxomethyl]amino]-3-(2-methoxy-5-methylphenyl)thioureaCavia porcellus (domestic guinea pig)Potency15.848910
1-[[(5-bromo-2-furanyl)-oxomethyl]amino]-3-(2,5-dimethylphenyl)thioureaCavia porcellus (domestic guinea pig)Potency39.810710
9-hydroxy-4-[1-oxo-2-[4-(phenylmethyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-[1]benzopyrano[3,4-b]pyridin-5-oneCavia porcellus (domestic guinea pig)Potency31.622810
4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(2,6-dimethylphenyl)benzamideCavia porcellus (domestic guinea pig)Potency39.810710
N-(1-ethyl-2-benzimidazolyl)-5-[(4-methyl-2-nitrophenoxy)methyl]-2-furancarboxamideCavia porcellus (domestic guinea pig)Potency10.000010
[3-amino-6-(4-methoxyphenyl)-2-thieno[2,3-b]pyridinyl]-(3,4-dimethoxyphenyl)methanoneCavia porcellus (domestic guinea pig)Potency19.952610
1-[[2-(4-chlorophenyl)-1-oxoethyl]amino]-3-(1-naphthalenyl)ureaCavia porcellus (domestic guinea pig)Potency25.118910
5-bromo-N-[[4-[(3,5-dimethylphenyl)sulfamoyl]anilino]-sulfanylidenemethyl]-2-furancarboxamideCavia porcellus (domestic guinea pig)Potency12.589310
N-[[3-chloro-4-(4-morpholinyl)anilino]-sulfanylidenemethyl]-2-(4-methoxyphenoxy)acetamideCavia porcellus (domestic guinea pig)Potency15.848910
N-[[3-chloro-4-(1-piperidinyl)anilino]-sulfanylidenemethyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamideCavia porcellus (domestic guinea pig)Potency10.000010
1,2,3,4-tetrahydroacridine-9-carboxylic acid (2-oxo-2-thiophen-2-ylethyl) esterCavia porcellus (domestic guinea pig)Potency31.622810
N-[2-[2-[2-(4-ethoxyanilino)-2-oxoethyl]-5-tetrazolyl]phenyl]-2-thiophenecarboxamideCavia porcellus (domestic guinea pig)Potency15.848910
N-[2-(2-pyridinyl)-3H-benzimidazol-5-yl]cyclohexanecarboxamideCavia porcellus (domestic guinea pig)Potency5.011910
5-(3-chlorophenyl)-N-(2-propyl-5-tetrazolyl)-2-furancarboxamideCavia porcellus (domestic guinea pig)Potency0.251210
N-[4-[[2-furanyl(oxo)methyl]amino]phenyl]-1,3-benzodioxole-5-carboxamideCavia porcellus (domestic guinea pig)Potency19.952610
1-[4-[3-[5-(2-furanyl)-1H-pyrazol-3-yl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]phenyl]ethanoneCavia porcellus (domestic guinea pig)Potency19.952610
N-[3-[2-[(4-methyl-2-pyridinyl)amino]-4-thiazolyl]phenyl]acetamideCavia porcellus (domestic guinea pig)Potency31.622810
5-(4-bromophenyl)-1-methyl-N-(3-pyridinylmethyl)-2-imidazolamineCavia porcellus (domestic guinea pig)Potency19.952610
N'-methyl-N-[1-methyl-5-(4-methylphenyl)-2-imidazolyl]-N'-(phenylmethyl)butanediamideCavia porcellus (domestic guinea pig)Potency31.622810
4-chloro-3-(1-piperidinylsulfonyl)-N-(2-thiazolyl)benzamideCavia porcellus (domestic guinea pig)Potency25.118910
ym-90709Cavia porcellus (domestic guinea pig)Potency25.118910
2-(1,3-benzodioxol-5-yl)-N-[(2-ethoxyphenyl)methyl]-N-(2-pyridinylmethyl)ethanamineCavia porcellus (domestic guinea pig)Potency25.118910
2-[(7-methoxy-4-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)thio]-N-methyl-N-(4-phenyl-2-thiazolyl)acetamideCavia porcellus (domestic guinea pig)Potency25.118910
N-[2,5-diethoxy-4-[[(3-methoxyanilino)-sulfanylidenemethyl]amino]phenyl]-4-methylbenzamideCavia porcellus (domestic guinea pig)Potency19.952610
N-[4-[[anilino(sulfanylidene)methyl]amino]-2,5-diethoxyphenyl]-4-methoxybenzamideCavia porcellus (domestic guinea pig)Potency25.118910
N-[4-[[anilino(sulfanylidene)methyl]amino]-2,5-diethoxyphenyl]benzamideCavia porcellus (domestic guinea pig)Potency25.118910
N-(2-furanylmethyl)-2-(4-oxo-6-phenyl-3-thieno[2,3-d]pyrimidinyl)acetamideCavia porcellus (domestic guinea pig)Potency31.622810
4-(5,6-dimethyl-1-benzimidazolyl)-5-phenylthieno[2,3-d]pyrimidineCavia porcellus (domestic guinea pig)Potency25.118910
benztropineCavia porcellus (domestic guinea pig)Potency19.952610
1-(2-chloro-10-phenothiazinyl)-2-[(1-methyl-5-tetrazolyl)thio]ethanoneCavia porcellus (domestic guinea pig)Potency6.309610
N-[(1,2-dihydroacenaphthylen-5-ylamino)-sulfanylidenemethyl]-2-phenoxyacetamideCavia porcellus (domestic guinea pig)Potency15.848910
3-[[[2-(3-methylphenyl)-4-quinolinyl]-oxomethyl]amino]-2-thiophenecarboxylic acid methyl esterCavia porcellus (domestic guinea pig)Potency19.952610
1-[[2-(3-bromo-4-methoxyphenyl)-1-oxoethyl]amino]-3-phenylthioureaCavia porcellus (domestic guinea pig)Potency1.584910
3,5-dimethoxy-N-[(2-phenylethylamino)-sulfanylidenemethyl]benzamideCavia porcellus (domestic guinea pig)Potency7.943310
1,4-dioxa-8-azaspiro[4.5]decan-8-yl(4,5,6,7-tetrahydro-1-benzothiophen-2-yl)methanoneCavia porcellus (domestic guinea pig)Potency7.943310
N-[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]-3-pyridinecarboxamideCavia porcellus (domestic guinea pig)Potency39.810710
N-[(3-methoxyphenyl)methyl]-1-propyl-5-benzimidazolamineCavia porcellus (domestic guinea pig)Potency12.589310
LSM-33266Cavia porcellus (domestic guinea pig)Potency25.118910
N-[2-methoxy-5-(2-oxo-1-benzopyran-3-yl)phenyl]-5-nitro-2-furancarboxamideCavia porcellus (domestic guinea pig)Potency25.118910
N-[[3-chloro-2-(4-morpholinyl)anilino]-sulfanylidenemethyl]-4-methoxy-3-nitrobenzamideCavia porcellus (domestic guinea pig)Potency12.589310
N-[[3-chloro-2-(1-piperidinyl)anilino]-sulfanylidenemethyl]-2-thiophenecarboxamideCavia porcellus (domestic guinea pig)Potency19.952610
2-(1-imidazolyl)-4-phenyl-6-(4-phenyl-1-piperazinyl)-1,3,5-triazineCavia porcellus (domestic guinea pig)Potency10.000010
2-[[(3,4-dimethoxyphenyl)-oxomethyl]amino]-N-(2-furanylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamideCavia porcellus (domestic guinea pig)Potency31.622810
2-(1,3-benzodioxol-5-ylmethylthio)-5-(2-furanyl)-3-prop-2-enyl-4-thieno[2,3-d]pyrimidinoneCavia porcellus (domestic guinea pig)Potency1.000010
darunavir ethanolateCavia porcellus (domestic guinea pig)Potency25.118910
[1-(2-phenoxyethyl)-3-indolyl]-(1-pyrrolidinyl)methanethioneCavia porcellus (domestic guinea pig)Potency25.118910
3-[[[(1-oxo-2,2-diphenylethyl)amino]-sulfanylidenemethyl]amino]benzoic acidCavia porcellus (domestic guinea pig)Potency15.848910
2-chloro-5-[[[[(3,5-dimethoxyphenyl)-oxomethyl]amino]-sulfanylidenemethyl]amino]benzoic acidCavia porcellus (domestic guinea pig)Potency12.589310
2-[2,5-dimethyl-3-[(2,4,6-trioxo-1,3-diazinan-5-ylidene)methyl]-1-pyrrolyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency10.000010
1-[2,3-bis(2-furanyl)-6-quinoxalinyl]-3-[4-(4-morpholinyl)phenyl]thioureaCavia porcellus (domestic guinea pig)Potency25.118910
N-[[4-(4-chlorophenoxy)anilino]-sulfanylidenemethyl]benzamideCavia porcellus (domestic guinea pig)Potency12.589310
N-[[5-(5,7-dimethyl-1,3-benzoxazol-2-yl)-2-methylanilino]-sulfanylidenemethyl]-2-thiophenecarboxamideCavia porcellus (domestic guinea pig)Potency6.309610
3-(3-oxo-2-benzo[f][1]benzopyranyl)-1-phenyl-4-pyrazolecarboxaldehydeCavia porcellus (domestic guinea pig)Potency19.952610
N-(2,3-dimethylphenyl)-2-[[6-(1,3-dioxo-2-isoindolyl)-1,3-benzothiazol-2-yl]thio]acetamideCavia porcellus (domestic guinea pig)Potency19.952610
3-[(1,3-benzothiazol-2-ylthio)methyl]-4-cyclohexyl-1H-1,2,4-triazole-5-thioneCavia porcellus (domestic guinea pig)Potency15.848910
5-(3-nitrophenyl)-N-[[2-(1-pyrrolidinyl)anilino]-sulfanylidenemethyl]-2-furancarboxamideCavia porcellus (domestic guinea pig)Potency7.943310
5,6-dimethyl-2-[1-[[1-(phenylmethyl)-5-tetrazolyl]methyl]-4-piperidinyl]-1H-benzimidazoleCavia porcellus (domestic guinea pig)Potency25.118910
2-[(2-propyl-4-quinazolinyl)thio]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideCavia porcellus (domestic guinea pig)Potency31.622810
1-[2-(5,6-dimethyl-1H-benzimidazol-2-yl)ethyl]-3-(2-methoxyphenyl)-1-(3-pyridinylmethyl)thioureaCavia porcellus (domestic guinea pig)Potency3.162310
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-phenylethyl)acetamideCavia porcellus (domestic guinea pig)Potency0.316210
N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-[4-[5-(trifluoromethyl)-1-benzotriazolyl]-1-piperidinyl]acetamideCavia porcellus (domestic guinea pig)Potency25.118910
4-chloro-N-(4-chloro-2-methylphenyl)-5-dithiazolimineCavia porcellus (domestic guinea pig)Potency39.810710
7-(4-methoxyphenyl)-2-(1-pyrrolyl)-[1,2,4]triazolo[1,5-a]pyrimidineCavia porcellus (domestic guinea pig)Potency31.622810
4-[(4-chloro-1-naphthalenyl)oxy]-5-methoxy-2-(2-pyridinyl)pyrimidineCavia porcellus (domestic guinea pig)Potency3.981110
N-[(4-methylphenyl)methyl]-2-(2-pyridinyl)-4-(trifluoromethyl)-5-pyrimidinecarboxamideCavia porcellus (domestic guinea pig)Potency25.118910
3-[4-ethyl-5-[(4-methylphenyl)methylthio]-1,2,4-triazol-3-yl]-1-phenyl-4-pyridazinoneCavia porcellus (domestic guinea pig)Potency25.118910
1,1-bis(4-chlorophenyl)-2-[(3-methoxyphenyl)methylamino]ethanolCavia porcellus (domestic guinea pig)Potency19.952610
2-[(2,4-dichlorophenyl)methylthio]-6,7-dimethoxy-3-(thiophen-2-ylmethyl)-4-quinazolinimineCavia porcellus (domestic guinea pig)Potency15.848910
sulindacCavia porcellus (domestic guinea pig)Potency12.589310
cis-resveratrolCavia porcellus (domestic guinea pig)Potency22.247210
zucapsaicinCavia porcellus (domestic guinea pig)Potency1.887910
fluoxetineCavia porcellus (domestic guinea pig)Potency16.939720
terbinafineCavia porcellus (domestic guinea pig)Potency25.118910
npc 15199Cavia porcellus (domestic guinea pig)Potency7.943310
4-(4-methylphenyl)-2-[[oxo-(2-oxo-1-benzopyran-3-yl)methyl]amino]-3-thiophenecarboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency25.118910
3-propoxy-N-[sulfanylidene-[3-(trifluoromethyl)anilino]methyl]benzamideCavia porcellus (domestic guinea pig)Potency19.952610
N-[[3-chloro-4-(1-piperidinyl)anilino]-sulfanylidenemethyl]hexanamideCavia porcellus (domestic guinea pig)Potency15.848910
N-[3-(dimethylamino)propyl]-9H-carbazole-3-carboxamideCavia porcellus (domestic guinea pig)Potency25.118910
N-[[[2-(2-methoxyphenoxy)-1-oxoethyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamideCavia porcellus (domestic guinea pig)Potency3.162310
1-ethyl-3-[[[2-(2-methylpropyl)-4-quinolinyl]-oxomethyl]amino]thioureaCavia porcellus (domestic guinea pig)Potency15.848910
3-bromo-4-methoxy-N-[(propan-2-ylamino)-sulfanylidenemethyl]benzamideCavia porcellus (domestic guinea pig)Potency12.589310
2-(2-methoxyethylthio)-N-(2-thiazolyl)benzamideCavia porcellus (domestic guinea pig)Potency19.952610
1-[2-(2-methylphenoxy)ethyl]-3-phenylthioureaCavia porcellus (domestic guinea pig)Potency12.589310
N4-ethyl-6-[2-(4-methylphenoxy)ethylthio]-N2-propan-2-yl-1,3,5-triazine-2,4-diamineCavia porcellus (domestic guinea pig)Potency25.118910
2-[[2-(3,5-dimethyl-1-pyrazolyl)-6-methyl-4-pyrimidinyl]amino]ethanolCavia porcellus (domestic guinea pig)Potency25.118910
1-[(3,4-dichlorophenyl)methyl]indole-2,3-dioneCavia porcellus (domestic guinea pig)Potency7.943310
4-(phenylmethyl)-3-[2-(4-propoxyphenyl)ethyl]-1H-1,2,4-triazole-5-thioneCavia porcellus (domestic guinea pig)Potency12.589310
2-[[[2-amino-1-(3-methoxypropyl)-3-pyrrolo[3,2-b]quinoxalinyl]-oxomethyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency3.162310
2-[[4-amino-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]thio]-N-(9-ethyl-3-carbazolyl)acetamideCavia porcellus (domestic guinea pig)Potency15.848910
2-[(2-methyl-4-benzofuro[3,2-d]pyrimidinyl)thio]-N-(phenylmethyl)acetamideCavia porcellus (domestic guinea pig)Potency31.622810
N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-[methyl-(phenylmethyl)sulfamoyl]benzamideCavia porcellus (domestic guinea pig)Potency31.622810
3-[3-[[2-oxo-2-(1,2,5-trimethyl-3-pyrrolyl)ethyl]thio]propyl]-1H-benzimidazol-2-oneCavia porcellus (domestic guinea pig)Potency25.118910
4-(2,3-dihydroindol-1-ylmethyl)-7-ethyl-1-benzopyran-2-oneCavia porcellus (domestic guinea pig)Potency25.118910
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-ethyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanoneCavia porcellus (domestic guinea pig)Potency19.952610
3-[[4-(2-benzofuranyl)-2-thiazolyl]methyl]-2-[(dimethylamino)methyl]-4-quinazolinoneCavia porcellus (domestic guinea pig)Potency7.943310
N-(2-methyl-1,3-benzothiazol-6-yl)-2,3-dihydro-1,4-benzodioxin-6-sulfonamideCavia porcellus (domestic guinea pig)Potency39.810710
3-[(4-acetyl-1-piperazinyl)sulfonyl]-N-(1H-benzimidazol-2-yl)benzamideCavia porcellus (domestic guinea pig)Potency39.810710
N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-2-quinolinecarboxamideCavia porcellus (domestic guinea pig)Potency25.118910
2-(2-fluorophenoxy)-N-[4-(2-furanylmethylsulfamoyl)phenyl]acetamideCavia porcellus (domestic guinea pig)Potency3.981110
4-(4-tert-butylphenoxy)-N-(4,5-dihydrothiazol-2-yl)butanamideCavia porcellus (domestic guinea pig)Potency15.848910
4-[ethyl-(phenylmethyl)sulfamoyl]-N-[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamideCavia porcellus (domestic guinea pig)Potency3.162310
4-[bis(2-methylpropyl)sulfamoyl]-N-[5-(3-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamideCavia porcellus (domestic guinea pig)Potency5.011910
1-(2,5-dimethoxyphenyl)-3-[2-(trifluoromethyl)-1,3-benzodioxol-2-yl]ureaCavia porcellus (domestic guinea pig)Potency10.000010
N9-(4-butoxyphenyl)-6,8,10-triazaspiro[4.5]deca-6,9-diene-7,9-diamineCavia porcellus (domestic guinea pig)Potency25.118910
N-[4-(dibutylsulfamoyl)phenyl]-2-thiophen-2-ylacetamideCavia porcellus (domestic guinea pig)Potency25.118910
4-[(2,4-dichlorophenoxy)methyl]-N-[2-(dimethylamino)ethyl]benzamideCavia porcellus (domestic guinea pig)Potency7.943310
N-(2-furanylmethyl)-2-(6,7,8,9-tetrahydro-5H-cyclohepta[2,3]thieno[2,4-d]pyrimidin-4-ylthio)acetamideCavia porcellus (domestic guinea pig)Potency25.118910
2-(2-bromo-4-tert-butylphenoxy)-N-(2-furanylmethyl)acetamideCavia porcellus (domestic guinea pig)Potency15.848910
2-((3-(2,3-dichlorophenoxy)propyl)amino)ethanolCavia porcellus (domestic guinea pig)Potency12.589310
N-(2,1,3-benzothiadiazol-4-yl)-5-(3-chlorophenyl)-2-furancarboxamideCavia porcellus (domestic guinea pig)Potency12.589310
3,4-dimethyl-N-[sulfanylidene-[2-(trifluoromethyl)anilino]methyl]benzamideCavia porcellus (domestic guinea pig)Potency25.118910
8-[2-(4-chloro-3,5-dimethylphenoxy)ethoxy]quinolineCavia porcellus (domestic guinea pig)Potency15.848910
1-chloro-2-[2-(2-methoxy-4-methylphenoxy)ethoxy]-4-methylbenzeneCavia porcellus (domestic guinea pig)Potency15.848910
8-[3-(3,4-dimethylphenoxy)propoxy]quinolineCavia porcellus (domestic guinea pig)Potency31.622810
N-(3-dibenzofuranyl)-2-[2-oxo-2-(2,4,6-trimethylanilino)ethoxy]benzamideCavia porcellus (domestic guinea pig)Potency19.952610
2-(4,6-dimethyl-2-pyrimidinyl)-4-[(4-fluorophenyl)thio]-5-methyl-3-pyrazolamineCavia porcellus (domestic guinea pig)Potency7.943310
2-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-1,2-benzothiazol-3-oneCavia porcellus (domestic guinea pig)Potency0.631010
5-[(2-chlorophenyl)hydrazo]-3,3-bis(hydroxymethyl)-2H-1,4-oxazin-6-oneCavia porcellus (domestic guinea pig)Potency15.848910
N-(5-methyl-3-isoxazolyl)-2-(2-naphthalenylthio)acetamideCavia porcellus (domestic guinea pig)Potency15.848910
3-(1-azepanylsulfonyl)-4-chloro-N-(1H-1,2,4-triazol-5-yl)benzamideCavia porcellus (domestic guinea pig)Potency1.258910
5-(4-propylphenyl)-1H-pyrazol-3-amineCavia porcellus (domestic guinea pig)Potency25.118910
3-(4-tert-butylphenoxy)-N-(4,5-dihydrothiazol-2-yl)propanamideCavia porcellus (domestic guinea pig)Potency19.952610
2-(1-benzimidazolyl)acetic acid [2-[1-(4-methoxyphenyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] esterCavia porcellus (domestic guinea pig)Potency12.589310
N-(6-methoxy-1,3-benzothiazol-2-yl)-3-(4-morpholinylsulfonyl)benzamideCavia porcellus (domestic guinea pig)Potency39.810710
3-[2-(2-furanylmethylamino)-2-oxoethoxy]-N-(2-methoxy-5-methylphenyl)-2-naphthalenecarboxamideCavia porcellus (domestic guinea pig)Potency15.848910
4,6,8-trimethyl-1H-quinoline-2-thioneCavia porcellus (domestic guinea pig)Potency25.118910
N-[4-(4-methoxyphenyl)-2-thiazolyl]-5-methyl-2-phenyl-4-oxazolecarboxamideCavia porcellus (domestic guinea pig)Potency25.118910
5-[[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)thio]methyl]-2-furancarboxylic acid methyl esterCavia porcellus (domestic guinea pig)Potency25.118910
5-[2-[[2-[[2-furanyl(oxo)methyl]amino]phenyl]-oxomethoxy]-1-oxoethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency0.158510
2-[[[4-cyclohexyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-oneCavia porcellus (domestic guinea pig)Potency15.848910
2-[[4-amino-6-(2-methylanilino)-1,3,5-triazin-2-yl]methyl-methylamino]-N-(2-ethylphenyl)acetamideCavia porcellus (domestic guinea pig)Potency1.995310
4-chloro-N-[3-[(3,5-dimethyl-4-isoxazolyl)methylthio]-2-quinoxalinyl]benzenesulfonamideCavia porcellus (domestic guinea pig)Potency31.622810
N-[5-chloro-2-(4-methyl-1-piperazinyl)phenyl]-3-(dimethylsulfamoyl)benzamideCavia porcellus (domestic guinea pig)Potency10.000010
3-(diethylsulfamoyl)-N-(3,5-dimethylphenyl)benzamideCavia porcellus (domestic guinea pig)Potency0.158510
5-chloro-2-mercaptobenzothiazoleCavia porcellus (domestic guinea pig)Potency25.118910
malachite greenCavia porcellus (domestic guinea pig)Potency5.011910
capsazepineCavia porcellus (domestic guinea pig)Potency8.390220
tamoxifen citrateCavia porcellus (domestic guinea pig)Potency17.783020
tamoxifenCavia porcellus (domestic guinea pig)Potency6.309610
tetraoctylammonium bromideCavia porcellus (domestic guinea pig)Potency31.622810
4-(benzenesulfonyl)-1-[(4-chlorophenyl)methyl]-4-piperidinecarboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency39.810710
2-[[sulfanylidene-[[2,2,2-trichloro-1-[[(2-nitrophenyl)-oxomethyl]amino]ethyl]amino]methyl]amino]benzoic acidCavia porcellus (domestic guinea pig)Potency10.000010
2-[[sulfanylidene-[[2,2,2-trichloro-1-[(1-oxo-2-phenoxyethyl)amino]ethyl]amino]methyl]amino]benzoic acidCavia porcellus (domestic guinea pig)Potency10.000010
N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-2-adamantanamineCavia porcellus (domestic guinea pig)Potency25.118910
1-(5-bicyclo[2.2.1]hept-2-enylmethyl)-4-[3-(trifluoromethyl)phenyl]piperazineCavia porcellus (domestic guinea pig)Potency15.848910
3,5,7-trimethyl-N-[4-morpholinyl(sulfanylidene)methyl]-1-adamantanecarboxamideCavia porcellus (domestic guinea pig)Potency19.952610
3,7-dimethyl-2-[4-(2-pyridinyl)-1-piperazinyl]quinolineCavia porcellus (domestic guinea pig)Potency19.952610
1-(3,5-dichlorophenyl)-3-(4-morpholinyl)pyrrolidine-2,5-dioneCavia porcellus (domestic guinea pig)Potency25.118910
4-ethyl-2-methoxy-3-phenyl-3,3a,9,9a-tetrahydropyrrolo[2,3-b]quinoxalineCavia porcellus (domestic guinea pig)Potency15.848910
3-[2-[4-(2-chloro-4-nitrophenyl)-1-piperazinyl]ethoxy]-4-phenyl-1,2,5-oxadiazoleCavia porcellus (domestic guinea pig)Potency31.622810
N-[4-bromo-2-[[(2-hydrazinyl-2-oxoethyl)amino]-phenylmethyl]phenyl]-3-(4-morpholinyl)propanamideCavia porcellus (domestic guinea pig)Potency25.118910
N-[5-[(4-methylphenyl)methyl]-2-thiazolyl]-2-oxolanecarboxamideCavia porcellus (domestic guinea pig)Potency31.622810
N-cyclohexyl-4-(4-nitrophenyl)-1-piperazinecarbothioamideCavia porcellus (domestic guinea pig)Potency25.118910
2,2'-[3-(2-methoxyphenyl)-1,2-propanediyl]bis(1H-benzimidazole)Cavia porcellus (domestic guinea pig)Potency0.079410
N-(1-butyl-2-benzimidazolyl)cyclohexanecarboxamideCavia porcellus (domestic guinea pig)Potency10.000010
N-(3,3,5-trimethylcyclohexyl)-1H-1,2,4-triazole-5-carboxamideCavia porcellus (domestic guinea pig)Potency39.810710
4-methylbenzenesulfonic acid [4-[bis(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-2-methoxyphenyl] esterCavia porcellus (domestic guinea pig)Potency25.118910
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]-N-[2-(4-morpholinyl)ethyl]acetamideCavia porcellus (domestic guinea pig)Potency3.162310
1-[4-(3-ethoxyphenoxy)butyl]imidazoleCavia porcellus (domestic guinea pig)Potency15.848910
4-methylbenzenesulfonic acid [4-[bis(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-2-ethoxyphenyl] esterCavia porcellus (domestic guinea pig)Potency10.000010
1-(2-furanylmethyl)-3-[(4-methylphenyl)methyl]pyrrolidine-2,5-dioneCavia porcellus (domestic guinea pig)Potency25.118910
benzenesulfonic acid [4-[bis(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-2-methoxyphenyl] esterCavia porcellus (domestic guinea pig)Potency7.943310
benzenesulfonic acid [4-[bis(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-2-ethoxyphenyl] esterCavia porcellus (domestic guinea pig)Potency25.118910
2-[[1-(4-chlorophenyl)-2,5-dioxo-3-pyrrolidinyl]-methylamino]acetic acid methyl esterCavia porcellus (domestic guinea pig)Potency12.589310
1-(2,4-dimethoxyphenyl)-3-[4-(4-morpholinyl)anilino]pyrrolidine-2,5-dioneCavia porcellus (domestic guinea pig)Potency31.622810
N-(4,5-dihydrothiazol-2-yl)-3,5-dimethyl-1-adamantanecarboxamideCavia porcellus (domestic guinea pig)Potency15.848910
4-[[[4-(2-furanylmethyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]benzonitrileCavia porcellus (domestic guinea pig)Potency31.622810
4-[cyclohexyl(methyl)amino]-N-(6-methyl-2-pyridinyl)-3-nitrobenzamideCavia porcellus (domestic guinea pig)Potency19.952610
4-(2,5-dimethylphenyl)-6-[[(4-methylphenyl)methylamino]methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency12.589310
4-(1,3-benzodioxol-5-yl)-6-[[2-(4-chlorophenyl)ethylamino]methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency39.810710
monastrolCavia porcellus (domestic guinea pig)Potency19.952610
nsc 727447Cavia porcellus (domestic guinea pig)Potency31.622810
1-[(6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl)methoxy]-3-(1-methyl-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazin-2-yl)-2-propanolCavia porcellus (domestic guinea pig)Potency15.848910
2-(4-anilinophenoxy)acetic acid [2-(2-furanylmethylamino)-2-oxoethyl] esterCavia porcellus (domestic guinea pig)Potency15.848910
4-chloro-N-(1-propyl-2-benzimidazolyl)-3-(1-pyrrolidinylsulfonyl)benzamideCavia porcellus (domestic guinea pig)Potency31.622810
2-chloro-N-[5-chloro-2-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamideCavia porcellus (domestic guinea pig)Potency12.589310
3-(2,5-dimethyl-3-furanyl)-5,6-diphenyl-1,2,4-triazineCavia porcellus (domestic guinea pig)Potency10.000010
bis(1-ethenyl-2-imidazolyl)-(9-ethyl-3-carbazolyl)-sulfanylidenephosphoraneCavia porcellus (domestic guinea pig)Potency3.162310
N-[1-oxo-1-[[4-(2-pyridinyl)-2-thiazolyl]amino]propan-2-yl]-2-furancarboxamideCavia porcellus (domestic guinea pig)Potency25.118910
N-[2-(2,4-dichlorophenyl)ethyl]-2-[[5-[1-(dimethylamino)propyl]-1,3,4-oxadiazol-2-yl]thio]acetamideCavia porcellus (domestic guinea pig)Potency15.848910
2-(2-furanyl)-N-(2-oxolanylmethyl)-4-quinolinecarboxamideCavia porcellus (domestic guinea pig)Potency12.589310
N-(1-propyl-2-benzimidazolyl)-3-(1-pyrrolidinylsulfonyl)benzamideCavia porcellus (domestic guinea pig)Potency31.622810
1,4-dimethoxy-10H-acridine-9-thioneCavia porcellus (domestic guinea pig)Potency7.943320
l 783281Cavia porcellus (domestic guinea pig)Potency20.690320
6-methyl-2-(phenylethynyl)pyridineCavia porcellus (domestic guinea pig)Potency10.000010
altanserinCavia porcellus (domestic guinea pig)Potency27.720520
racloprideCavia porcellus (domestic guinea pig)Potency7.943310
zuclomifene citrateCavia porcellus (domestic guinea pig)Potency0.079410
1,3-dimethyl-8-[2-(1-pyrrolidinyl)ethylthio]-6-sulfanylidene-7H-purin-2-oneCavia porcellus (domestic guinea pig)Potency3.162310
4-phenyl-1-(4-phenylbutyl)piperidineCavia porcellus (domestic guinea pig)Potency10.000010
triptorelinCavia porcellus (domestic guinea pig)Potency2.511910
thioperamideCavia porcellus (domestic guinea pig)Potency2.233220
bp 897Cavia porcellus (domestic guinea pig)Potency6.309610
homoquinolinic acidCavia porcellus (domestic guinea pig)Potency19.952610
ici 199441Cavia porcellus (domestic guinea pig)Potency5.095720
2-(2,4-dioxo-3-phenyl-5-thiazolidinyl)-N-(3-methylphenyl)acetamideCavia porcellus (domestic guinea pig)Potency15.848910
3-(4-fluorophenyl)-5-(2-furanyl)-2-phenyl-3,4-dihydropyrazoleCavia porcellus (domestic guinea pig)Potency3.162310
2-[(prop-2-enylthio)-(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]propanedinitrileCavia porcellus (domestic guinea pig)Potency19.952610
2-chloro-N-[1-[oxo(10-phenothiazinyl)methyl]-4-piperidinyl]benzamideCavia porcellus (domestic guinea pig)Potency19.952610
N-(3-chlorophenyl)-4-[4-(3-methoxyphenyl)-2-thiazolyl]-1-piperazinecarbothioamideCavia porcellus (domestic guinea pig)Potency19.952610
3-(5-methyl-2-furanyl)-5-[1-(2-naphthalenylsulfonyl)-3-piperidinyl]-1,2,4-oxadiazoleCavia porcellus (domestic guinea pig)Potency12.589310
1-(2-methyl-2,3-dihydroindol-1-yl)-2-[4-[5-(trifluoromethyl)-1-benzotriazolyl]-1-piperidinyl]ethanoneCavia porcellus (domestic guinea pig)Potency12.589310
1-(1-tert-butyl-5-tetrazolyl)-N-(phenylmethyl)-1-(3-pyridinyl)-N-(thiophen-2-ylmethyl)methanamineCavia porcellus (domestic guinea pig)Potency25.118910
7-(2-ethyl-1-piperidinyl)-5-methyl-2-(3-methylphenyl)pyrazolo[1,5-a]pyrimidineCavia porcellus (domestic guinea pig)Potency39.810710
N-[4-[1-(benzenesulfonyl)-2,3-dihydroindol-5-yl]-5-methyl-2-thiazolyl]-2-(4-morpholinyl)acetamideCavia porcellus (domestic guinea pig)Potency19.952610
ml106Cavia porcellus (domestic guinea pig)Potency0.794310
6-(1,3-benzodioxol-5-yl)-N-(2-furanylmethyl)-N-methyl-4-quinazolinamineCavia porcellus (domestic guinea pig)Potency1.258910
N-(2-furanylmethyl)-6-(3-methoxyphenyl)-N-methyl-4-quinazolinamineCavia porcellus (domestic guinea pig)Potency1.258910
6-(1,3-benzodioxol-5-yl)-N-[(3-methylphenyl)methyl]-4-quinazolinamineCavia porcellus (domestic guinea pig)Potency2.713620
6-(2-chlorophenyl)-N-(3-pyridinylmethyl)-4-quinazolinamineCavia porcellus (domestic guinea pig)Potency8.457620
6-(3-furanyl)-N-[(3-methylphenyl)methyl]-4-quinazolinamineCavia porcellus (domestic guinea pig)Potency10.647620
6-(3-pyridinyl)-N-(3-pyridinylmethyl)-4-quinazolinamineCavia porcellus (domestic guinea pig)Potency25.118910
6-(3-methoxyphenyl)-N-(3-pyridinylmethyl)-4-quinazolinamineCavia porcellus (domestic guinea pig)Potency10.998520
6-(2-chlorophenyl)-N-(2-furanylmethyl)-N-methyl-4-quinazolinamineCavia porcellus (domestic guinea pig)Potency16.875220
6-(3-methoxyphenyl)-N-(thiophen-2-ylmethyl)-4-quinazolinamineCavia porcellus (domestic guinea pig)Potency0.631010
N-[(3-methylphenyl)methyl]-6-(3-pyridinyl)-4-quinazolinamineCavia porcellus (domestic guinea pig)Potency3.981110
N-(2,4-dimethoxyphenyl)-2-[1-(3,4-dimethylphenyl)-4-oxo-5-pyrazolo[3,4-d]pyrimidinyl]acetamideCavia porcellus (domestic guinea pig)Potency25.118910
N-[2-(1-cyclohexenyl)ethyl]-3-(1,3-dioxo-2-isoindolyl)propanamideCavia porcellus (domestic guinea pig)Potency12.589310
3-[4-[(2-hydroxy-5-phenylphenyl)methyl]-1-piperazinyl]propanenitrileCavia porcellus (domestic guinea pig)Potency19.952610
2-[(6-fluoro-1,3-benzothiazol-2-yl)amino]-4-thiazolecarboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency3.981110
N-[3-(1-azepanyl)propyl]-1-[(4-methoxyphenyl)methyl]-5-oxo-3-pyrrolidinecarboxamideCavia porcellus (domestic guinea pig)Potency25.118910
N-[3-(diethylamino)propyl]-6-(4-fluorophenyl)-3-methyl-2-imidazo[2,1-b]thiazolecarboxamideCavia porcellus (domestic guinea pig)Potency31.622810
1-(4-bromophenyl)sulfonyl-4-[(3-methoxyphenyl)methyl]-1,4-diazepaneCavia porcellus (domestic guinea pig)Potency25.118910
1-(4-methyl-2-prop-2-enylphenoxy)-3-(4-phenyl-1-piperazinyl)-2-propanolCavia porcellus (domestic guinea pig)Potency19.952610
5-(phenylmethoxymethyl)-7-(1-piperidinylmethyl)-8-quinolinolCavia porcellus (domestic guinea pig)Potency1.584910
4-(2,3-dihydroindol-1-yl)-N-[3-(N-ethyl-3-methylanilino)propyl]-3-(1-imidazolyl)-4-oxobutanamideCavia porcellus (domestic guinea pig)Potency2.511910
2-(6-benzimidazolo[1,2-c]quinazolinylthio)-N-(2-furanylmethyl)acetamideCavia porcellus (domestic guinea pig)Potency12.589310
N-[3-(1-imidazolyl)propyl]-7-methoxy-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamideCavia porcellus (domestic guinea pig)Potency7.943310
N-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-2-[[1-oxo-2-(1-oxo-2-isoquinolinyl)ethyl]amino]acetamideCavia porcellus (domestic guinea pig)Potency19.952610
1-[bis(prop-2-enyl)amino]-3-(9-carbazolyl)-2-propanolCavia porcellus (domestic guinea pig)Potency19.952610
LSM-18934Cavia porcellus (domestic guinea pig)Potency25.118910
2-(2,4-dimethoxyanilino)-N-[3-(4-methyl-1-piperazinyl)propyl]-4-quinolinecarboxamideCavia porcellus (domestic guinea pig)Potency25.118910
6-(1,3-benzodioxol-5-ylmethylamino)-3-(2-methylphenyl)-1H-pyrimidine-2,4-dioneCavia porcellus (domestic guinea pig)Potency6.309610
4-[[2-(3-ethylanilino)-3,4-dioxo-1-cyclobutenyl]amino]-1-piperidinecarboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency12.589310
N-[3-(1-azepanyl)propyl]-2-(4-morpholinyl)-3-oxo-4H-1,4-benzothiazine-6-carboxamideCavia porcellus (domestic guinea pig)Potency31.622810
3-(2-furanylmethyl)-5-(2-methoxyethyl)-1,3,5-thiadiazinane-2-thioneCavia porcellus (domestic guinea pig)Potency15.848910
[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-(7-methoxy-2-furo[2,3-b]quinolinyl)methanoneCavia porcellus (domestic guinea pig)Potency25.118910
7-[(4-methyl-1-piperazinyl)methyl]-5-(phenylmethoxymethyl)-8-quinolinolCavia porcellus (domestic guinea pig)Potency1.584910
3-methyl-N-[2-(4-morpholinyl)ethyl]-1-phenyl-5-thieno[2,3-c]pyrazolecarboxamideCavia porcellus (domestic guinea pig)Potency15.848910
N-(3,4-dimethylphenyl)-3-[(4-fluorophenyl)methyl]-1,3-diazinane-1-carboxamideCavia porcellus (domestic guinea pig)Potency31.622810
1-[3-[4-(2-fluorophenyl)-1-piperazinyl]propyl]-3-[4-(methylthio)phenyl]ureaCavia porcellus (domestic guinea pig)Potency25.118910
7-(5-chloro-2-methoxyanilino)-6-[(4-methoxyphenyl)methyl]-7H-pyrrolo[3,4-b]pyridin-5-oneCavia porcellus (domestic guinea pig)Potency25.118910
N-[2-[4-(3-chlorophenyl)-1-piperazinyl]ethyl]-[1,2,4]triazolo[4,3-a]quinoxalin-4-amineCavia porcellus (domestic guinea pig)Potency25.118910
LSM-16579Cavia porcellus (domestic guinea pig)Potency12.589310
N-(4-fluorophenyl)-6-methyl-1-propyl-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-2-carboxamideCavia porcellus (domestic guinea pig)Potency39.810710
N-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-2-[(1-ethyl-2-oxo-4-quinolinyl)oxy]acetamideCavia porcellus (domestic guinea pig)Potency25.118910
1-[[5-methyl-2-(2-methylphenyl)-4-oxazolyl]methyl]-N-(3-pyridinylmethyl)-4-piperidinecarboxamideCavia porcellus (domestic guinea pig)Potency25.118910
7-(2,4-dichlorophenyl)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidine-6-carbonitrileCavia porcellus (domestic guinea pig)Potency19.952610
N-[3-(3,5-dimethyl-1-piperidinyl)propyl]-1-[[5-methyl-2-(2-methylphenyl)-4-oxazolyl]methyl]-4-piperidinecarboxamideCavia porcellus (domestic guinea pig)Potency15.848910
5-(1,3-benzodioxol-5-yl)-3-[3-(methylthio)phenyl]-1H-imidazol-2-oneCavia porcellus (domestic guinea pig)Potency15.848910
2-[2,4-dioxo-3-(phenylmethyl)-1-quinazolinyl]-N-(5-methyl-3-isoxazolyl)acetamideCavia porcellus (domestic guinea pig)Potency19.952610
N-cyclopentyl-4-(3,4-dimethoxyphenyl)-6-(trifluoromethyl)-2-pyrimidinamineCavia porcellus (domestic guinea pig)Potency0.251210
2-[[3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]thio]-N-(2-oxolanylmethyl)acetamideCavia porcellus (domestic guinea pig)Potency39.810710
N-[3-(cyclohexylthio)propyl]-1-[(4-methyl-5-thieno[3,2-b]pyrrolyl)-oxomethyl]-3-piperidinecarboxamideCavia porcellus (domestic guinea pig)Potency25.118910
1-[3-[2-(dimethylamino)ethylamino]-3-oxopropyl]-2-methyl-5-(4-methylphenyl)-3-pyrrolecarboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency12.589310
cambinolCavia porcellus (domestic guinea pig)Potency6.030920
N-[(S)-[(1S,2R)-1-methyl-2-[(2R)-1-[(5-methyl-2-furanyl)methylamino]-1-oxopropan-2-yl]cyclopropyl]-phenylmethyl]carbamic acid (phenylmethyl) esterCavia porcellus (domestic guinea pig)Potency16.047620
N-[(S)-[(1S,2R)-1-methyl-2-[(2R)-1-oxo-1-[(phenylmethyl)amino]propan-2-yl]cyclopropyl]-phenylmethyl]carbamic acid (phenylmethyl) esterCavia porcellus (domestic guinea pig)Potency10.000010
(1R,2R)-2-[(R)-(diphenylphosphorylamino)-phenylmethyl]-N-(2-naphthalenyl)-1-cyclopropanecarboxamideCavia porcellus (domestic guinea pig)Potency7.943310
5-methyl-N-[(S)-[(1S,2R)-1-methyl-2-[(2R)-1-(2-naphthalenylamino)-1-oxopropan-2-yl]cyclopropyl]-phenylmethyl]-3-isoxazolecarboxamideCavia porcellus (domestic guinea pig)Potency3.981110
2,5-dimethyl-N-[(S)-[(1S,2R)-1-methyl-2-[(2R)-1-(2-naphthalenylamino)-1-oxopropan-2-yl]cyclopropyl]-phenylmethyl]-3-pyrazolecarboxamideCavia porcellus (domestic guinea pig)Potency7.943310
4-chlorobenzoic acid (5-methyl-2-pyridin-4-yl-4-thiazolyl) esterCavia porcellus (domestic guinea pig)Potency19.952610
5-amino-2-(3-nitrophenyl)-1-phenyl-2H-pyrrole-3,3,4-tricarbonitrileCavia porcellus (domestic guinea pig)Potency39.810710
sb 203186Cavia porcellus (domestic guinea pig)Potency1.995310
n-(1-methyl-5-indolyl)-n'-(3-methyl-5-isothiazolyl)ureaCavia porcellus (domestic guinea pig)Potency2.511910
2-amino-6-ethyl-4-(4-methoxyphenyl)-8-[(4-methoxyphenyl)methyl]-4,5-dihydropyrano[3,2-c]pyridine-3-carbonitrileCavia porcellus (domestic guinea pig)Potency25.118910
sb-224289Cavia porcellus (domestic guinea pig)Potency10.598220
5-methyl-2-(2-phenoxyethyl)-4-phenyl-1,2,4-triazol-3-oneCavia porcellus (domestic guinea pig)Potency25.118910
gw 7647Cavia porcellus (domestic guinea pig)Potency31.622820
4-butyl-3-(6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-3-yl)-1H-1,2,4-triazole-5-thioneCavia porcellus (domestic guinea pig)Potency12.589310
sto 609Cavia porcellus (domestic guinea pig)Potency0.158510
ro 41-0960Cavia porcellus (domestic guinea pig)Potency1.258910
rs 100329Cavia porcellus (domestic guinea pig)Potency31.622810
n-(2-(4-(4-chlorophenyl)piperazin-1-yl)ethyl)-3-methoxybenzamideCavia porcellus (domestic guinea pig)Potency19.952610
l 663536Cavia porcellus (domestic guinea pig)Potency12.589310
mrs 1523Cavia porcellus (domestic guinea pig)Potency7.943310
1-phenyl-2-[[4-(trifluoromethyl)phenyl]methylthio]imidazoleCavia porcellus (domestic guinea pig)Potency15.848910
2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)thio]propanoic acid methyl esterCavia porcellus (domestic guinea pig)Potency39.810710
4-[4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-piperidinyl]-3-nitrobenzoic acid methyl esterCavia porcellus (domestic guinea pig)Potency3.162310
2-hydroxy-2-pentyl-N'-phenylheptanehydrazideCavia porcellus (domestic guinea pig)Potency3.162310
5-tert-butyl-7-(4-ethyl-1-piperazinyl)-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidineCavia porcellus (domestic guinea pig)Potency15.848910
5,7-dimethyl-3-phenyldiazenyl-1H-pyrazolo[1,5-a]pyrimidin-2-oneCavia porcellus (domestic guinea pig)Potency15.848910
N-(4-phenylmethoxyphenyl)-3-[4-(phenylmethyl)-1-piperazinyl]propanamideCavia porcellus (domestic guinea pig)Potency25.118910
1-[4-(2-chlorophenoxy)butyl]imidazoleCavia porcellus (domestic guinea pig)Potency15.848910
4-(2-chlorophenoxy)-5-methoxy-2-(2-pyridinyl)pyrimidineCavia porcellus (domestic guinea pig)Potency1.000010
rose bengal(2-)Cavia porcellus (domestic guinea pig)Potency7.943310
or486Cavia porcellus (domestic guinea pig)Potency5.397210
1-(2,4-dichlorophenyl)-3-[3-(1-imidazolyl)propyl]ureaCavia porcellus (domestic guinea pig)Potency19.952610
rs 17053Cavia porcellus (domestic guinea pig)Potency6.309610
ro 106-9920Cavia porcellus (domestic guinea pig)Potency2.511910
1-(2-fluorophenyl)-3-(N-(phenylmethyl)anilino)thioureaCavia porcellus (domestic guinea pig)Potency19.952610
suramin sodiumCavia porcellus (domestic guinea pig)Potency12.589310
mm 77Cavia porcellus (domestic guinea pig)Potency3.981110
2-phenylmelatoninCavia porcellus (domestic guinea pig)Potency15.848910
4-[(3-methyl-5-nitro-4-imidazolyl)amino]phenolCavia porcellus (domestic guinea pig)Potency10.000010
cp 94253Cavia porcellus (domestic guinea pig)Potency11.035720
4-(1-phenylethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thioneCavia porcellus (domestic guinea pig)Potency15.848910
2-[[[[[5-[(4-chloro-1-pyrazolyl)methyl]-2-furanyl]-oxomethyl]amino]-sulfanylidenemethyl]amino]-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency15.848910
iik7Cavia porcellus (domestic guinea pig)Potency1.258910
2-[(3-fluorophenyl)-(2-pyridinylamino)methyl]-3-hydroxy-6-(hydroxymethyl)-4-pyranoneCavia porcellus (domestic guinea pig)Potency7.943310
2-[1-[4-(diethylamino)phenyl]-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-N-phenylacetamideCavia porcellus (domestic guinea pig)Potency25.118910
sb 415286Cavia porcellus (domestic guinea pig)Potency31.622810
2-[4-(9H-fluoren-9-yl)-1-piperazinyl]-N-(4-methoxyphenyl)acetamideCavia porcellus (domestic guinea pig)Potency39.810710
5-methyl-4-[(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)-[1-(1-naphthalenylmethyl)-3-indolyl]methyl]-1,2-dihydropyrazol-3-oneCavia porcellus (domestic guinea pig)Potency3.981110
LSM-26445Cavia porcellus (domestic guinea pig)Potency19.952610
LY-310762Cavia porcellus (domestic guinea pig)Potency8.932020
gr 103691Cavia porcellus (domestic guinea pig)Potency0.039810
am 281Cavia porcellus (domestic guinea pig)Potency6.309610
am 630Cavia porcellus (domestic guinea pig)Potency6.309610
sc 560Cavia porcellus (domestic guinea pig)Potency25.118910
sb 408124Cavia porcellus (domestic guinea pig)Potency6.309610
le 300Cavia porcellus (domestic guinea pig)Potency10.000010
2-methyl-2,6-diphenyl-7-oxa-1-azabicyclo[2.2.1]heptaneCavia porcellus (domestic guinea pig)Potency3.981110
cfm 2Cavia porcellus (domestic guinea pig)Potency39.810710
N-(1-dibutoxyphosphoryl-4-oxo-1-naphthalenyl)benzenesulfonamideCavia porcellus (domestic guinea pig)Potency6.309610
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamideCavia porcellus (domestic guinea pig)Potency1.258910
N-(1H-benzimidazol-2-yl)-3-phenylbutanamideCavia porcellus (domestic guinea pig)Potency10.000010
1-[(4-fluorophenyl)-oxomethyl]-3-[(5-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)thio]-2-azepanoneCavia porcellus (domestic guinea pig)Potency31.622810
4-(4-propan-2-ylphenyl)-3,4,5,6-tetrahydro-1H-benzo[h]quinazolin-2-oneCavia porcellus (domestic guinea pig)Potency15.848910
ly 367265Cavia porcellus (domestic guinea pig)Potency25.118910
rabeprazole(1-)Cavia porcellus (domestic guinea pig)Potency12.589310
4-(4-chlorophenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thioneCavia porcellus (domestic guinea pig)Potency12.589310
2-phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamineCavia porcellus (domestic guinea pig)Potency25.118910
N-(4-tert-butylphenyl)-2-[4-(1-imidazolyl)phenoxy]acetamideCavia porcellus (domestic guinea pig)Potency3.162310
3,7-dichloro-N-[3-(1-imidazolyl)propyl]-6-methoxy-1-benzothiophene-2-carboxamideCavia porcellus (domestic guinea pig)Potency6.309610
8-(4-methoxyphenyl)-7-methyl-3-(phenylmethyl)purine-2,6-dioneCavia porcellus (domestic guinea pig)Potency15.848910
4-amino-5-cyano-2-(1-naphthalenylmethylthio)-3-azaspiro[5.5]undeca-2,4-diene-1-carboxamideCavia porcellus (domestic guinea pig)Potency39.810710
3-methoxy-N-[2-(4-methoxyphenyl)-2-(1-pyrrolidinyl)ethyl]-2-naphthalenecarboxamideCavia porcellus (domestic guinea pig)Potency25.118910
N-(3,4-dimethylphenyl)-2-[[1-(phenylmethyl)-2-imidazolyl]thio]acetamideCavia porcellus (domestic guinea pig)Potency12.589310
N-[[[2-(2-naphthalenyloxy)-1-oxopropyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamideCavia porcellus (domestic guinea pig)Potency0.794310
N-[3-(2-methylcyclohexyl)-2,4-dihydro-1H-1,3,5-triazin-6-yl]-1,3-benzothiazol-2-amineCavia porcellus (domestic guinea pig)Potency12.589310
LSM-4833Cavia porcellus (domestic guinea pig)Potency15.848910
3-(3,4-dimethoxyphenyl)-2,5-dimethyl-7-[4-(phenylmethyl)-1-piperazinyl]pyrazolo[1,5-a]pyrimidineCavia porcellus (domestic guinea pig)Potency12.589310
N'-(4-nitrophenyl)-9-oxo-3-bicyclo[3.3.1]nonanecarbohydrazideCavia porcellus (domestic guinea pig)Potency12.589310
diclofenac sodiumCavia porcellus (domestic guinea pig)Potency4.764110
cgp 7930Cavia porcellus (domestic guinea pig)Potency0.007910
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acidCavia porcellus (domestic guinea pig)Potency31.622810
1,3,5-tris(4-hydroxyphenyl)-4-propyl-1h-pyrazoleCavia porcellus (domestic guinea pig)Potency3.162310
1-cyclohexyl-N-(3-methylbutyl)-5-benzimidazolecarboxamideCavia porcellus (domestic guinea pig)Potency10.000010
(3,5-dichloroanilino)thioureaCavia porcellus (domestic guinea pig)Potency2.511910
N-[[(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-sulfanylidenemethyl]-2-methylbenzamideCavia porcellus (domestic guinea pig)Potency25.118910
5,6-dimethyl-1-octyl-4-benzimidazolamineCavia porcellus (domestic guinea pig)Potency15.848910
sib 1757Cavia porcellus (domestic guinea pig)Potency20.202720
fraxetinCavia porcellus (domestic guinea pig)Potency25.118910
quercetinCavia porcellus (domestic guinea pig)Potency12.645720
biochanin aCavia porcellus (domestic guinea pig)Potency0.025110
formononetinCavia porcellus (domestic guinea pig)Potency0.010010
arachidonyltrifluoromethaneCavia porcellus (domestic guinea pig)Potency19.952610
acacetinCavia porcellus (domestic guinea pig)Potency1.258910
apigeninCavia porcellus (domestic guinea pig)Potency18.317410
luteolinCavia porcellus (domestic guinea pig)Potency20.938020
hymecromoneCavia porcellus (domestic guinea pig)Potency12.589310
daphnetinCavia porcellus (domestic guinea pig)Potency7.943310
kaempferolCavia porcellus (domestic guinea pig)Potency12.223620
alpha-linolenic acidCavia porcellus (domestic guinea pig)Potency14.125410
harmineCavia porcellus (domestic guinea pig)Potency15.848910
naringenin chalconeCavia porcellus (domestic guinea pig)Potency31.622810
genisteinCavia porcellus (domestic guinea pig)Potency1.000010
pyrantel pamoateCavia porcellus (domestic guinea pig)Potency25.118910
brompheniramine maleateCavia porcellus (domestic guinea pig)Potency15.848910
norbixinCavia porcellus (domestic guinea pig)Potency31.622810
harmanCavia porcellus (domestic guinea pig)Potency15.848910
baicaleinCavia porcellus (domestic guinea pig)Potency6.184520
chrysinCavia porcellus (domestic guinea pig)Potency5.011910
3,7,4'-trihydroxyflavoneCavia porcellus (domestic guinea pig)Potency10.000010
fisetinCavia porcellus (domestic guinea pig)Potency20.864020
galanginCavia porcellus (domestic guinea pig)Potency3.162310
mangostinCavia porcellus (domestic guinea pig)Potency5.011910
morinCavia porcellus (domestic guinea pig)Potency10.000010
myricetinCavia porcellus (domestic guinea pig)Potency7.119620
rhamnetinCavia porcellus (domestic guinea pig)Potency12.589310
tricetinCavia porcellus (domestic guinea pig)Potency12.589310
daidzeinCavia porcellus (domestic guinea pig)Potency6.309610
caffeic acid phenethyl esterCavia porcellus (domestic guinea pig)Potency10.000010
ellagic acidCavia porcellus (domestic guinea pig)Potency19.224220
ginkgolic acidCavia porcellus (domestic guinea pig)Potency25.118910
tectochrysinCavia porcellus (domestic guinea pig)Potency2.511910
anandamideCavia porcellus (domestic guinea pig)Potency0.141310
arachidonyl dopamineCavia porcellus (domestic guinea pig)Potency8.912510
n-oleoyldopamineCavia porcellus (domestic guinea pig)Potency2.102420
sofalconeCavia porcellus (domestic guinea pig)Potency35.481310
trimipramine maleateCavia porcellus (domestic guinea pig)Potency12.589310
flunarizine hydrochlorideCavia porcellus (domestic guinea pig)Potency10.000010
10-octadecenoic acid, (z)-isomerCavia porcellus (domestic guinea pig)Potency36.535520
n-arachidonylglycineCavia porcellus (domestic guinea pig)Potency5.561010
n-oleoylethanolamineCavia porcellus (domestic guinea pig)Potency31.622810
perhexiline maleateCavia porcellus (domestic guinea pig)Potency31.622810
quercetinCavia porcellus (domestic guinea pig)Potency4.600020
dothiepinCavia porcellus (domestic guinea pig)Potency15.848910
ic 261Cavia porcellus (domestic guinea pig)Potency25.118910
su 9516Cavia porcellus (domestic guinea pig)Potency15.848910
4-[[[1-[[2-(3-chlorophenyl)-5-methyl-4-oxazolyl]methyl]-3-piperidinyl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency19.952610
2-[2-oxo-6-(1-pyrrolidinylsulfonyl)-1,3-benzoxazol-3-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamideCavia porcellus (domestic guinea pig)Potency31.622810
3,4-dihydro-1H-isoquinolin-2-yl-(4-ethyl-5-thieno[3,2-b]pyrrolyl)methanoneCavia porcellus (domestic guinea pig)Potency25.118910
3-(4-chlorophenyl)-1-methyl-N-[3-(1-pyrrolidinyl)propyl]-5-thieno[2,3-c]pyrazolecarboxamideCavia porcellus (domestic guinea pig)Potency15.848910
[4-(3-methoxyphenyl)-1-piperazinyl]-[2-(1-piperidinyl)-1,3-benzothiazol-6-yl]methanoneCavia porcellus (domestic guinea pig)Potency15.848910
8-(2-chlorophenyl)-3-(4-ethoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrileCavia porcellus (domestic guinea pig)Potency10.000010
arachidonylcyclopropylamideCavia porcellus (domestic guinea pig)Potency0.891310
4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamideCavia porcellus (domestic guinea pig)Potency3.162310
dexmedetomidineCavia porcellus (domestic guinea pig)Potency0.199510
irl 2500Cavia porcellus (domestic guinea pig)Potency39.810710
k 185Cavia porcellus (domestic guinea pig)Potency3.981110
l 745870Cavia porcellus (domestic guinea pig)Potency10.266310
dl-threo-beta-benzyloxyaspartateCavia porcellus (domestic guinea pig)Potency10.000010
n-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl)benzamideCavia porcellus (domestic guinea pig)Potency12.589310
l803087Cavia porcellus (domestic guinea pig)Potency22.387210
ici 185282Cavia porcellus (domestic guinea pig)Potency19.952610
sr 59230aCavia porcellus (domestic guinea pig)Potency7.943310
4-carboxy-3-hydroxyphenylglycineCavia porcellus (domestic guinea pig)Potency15.848910
cgp 71683 aCavia porcellus (domestic guinea pig)Potency28.183810
su 6656Cavia porcellus (domestic guinea pig)Potency10.000010
ro 4-6790Cavia porcellus (domestic guinea pig)Potency1.995310
7,7-dimethyl-5,8-eicosadienoic acidCavia porcellus (domestic guinea pig)Potency15.848910
2',6'-dihydroxy-4'-methoxychalconeCavia porcellus (domestic guinea pig)Potency1.995310
5,7,2'-trihydroxyflavoneCavia porcellus (domestic guinea pig)Potency5.011910
tyrphostin ag 555Cavia porcellus (domestic guinea pig)Potency31.622810
tyrphostin ag-494Cavia porcellus (domestic guinea pig)Potency31.622810
tyrphostin b44Cavia porcellus (domestic guinea pig)Potency12.949820
ag 556Cavia porcellus (domestic guinea pig)Potency6.349020
ag-490Cavia porcellus (domestic guinea pig)Potency16.075020
2'-hydroxy-4-methoxychalconeCavia porcellus (domestic guinea pig)Potency3.981110
sulindac sulfideCavia porcellus (domestic guinea pig)Potency35.481310
6,7-dihydroxyflavoneCavia porcellus (domestic guinea pig)Potency25.118910
7,8-dihydroxy-4-methylcoumarinCavia porcellus (domestic guinea pig)Potency10.000010
fluvoxamineCavia porcellus (domestic guinea pig)Potency15.098320
5,6-dichloro-1H-imidazo[4,5-b]pyrazine-2-carboxylic acidCavia porcellus (domestic guinea pig)Potency0.631010
(5R)-3'-phenyl-1-(phenylmethyl)spiro[1,3-diazinane-5,5'-2,4,4a,6-tetrahydro-1H-pyrazino[1,2-a]quinoline]-2,4,6-trioneCavia porcellus (domestic guinea pig)Potency31.622810
3-(1-benzimidazolyl)-6-ethyl-7-hydroxy-1-benzopyran-4-oneCavia porcellus (domestic guinea pig)Potency3.981110
zimeldineCavia porcellus (domestic guinea pig)Potency8.479020
papaverolineCavia porcellus (domestic guinea pig)Potency5.011910
cisplatinCavia porcellus (domestic guinea pig)Potency3.162310
6-[4-methyl-6-(4-nitrophenyl)-2-oxo-5-phenylmethoxycarbonyl-1,6-dihydropyrimidin-3-yl]hexanoic acidCavia porcellus (domestic guinea pig)Potency15.848910
s-trans,trans-farnesylthiosalicylic acidCavia porcellus (domestic guinea pig)Potency20.202720
bergamottinCavia porcellus (domestic guinea pig)Potency0.031610
ici 118551Cavia porcellus (domestic guinea pig)Potency5.011910
ethaverine hydrochlorideCavia porcellus (domestic guinea pig)Potency25.118910
fendiline hydrochlorideCavia porcellus (domestic guinea pig)Potency12.589310
methylbenzethonium chlorideCavia porcellus (domestic guinea pig)Potency3.981110
N-(1,3-benzodioxol-5-yl)-2-[(8-methoxy-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]acetamideCavia porcellus (domestic guinea pig)Potency25.118910
gw-5074Cavia porcellus (domestic guinea pig)Potency14.703420
obtusaquinoneCavia porcellus (domestic guinea pig)Potency10.000010
nf023Cavia porcellus (domestic guinea pig)Potency12.589310
nf 449Cavia porcellus (domestic guinea pig)Potency0.398110
3,5-di-tert-butylchalcone 4'-carboxylic acidCavia porcellus (domestic guinea pig)Potency7.943310
3-[(1S)-1-phenylethyl]-4-imidazolecarboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency12.589310
N-(3,4-dichlorophenyl)-6-(1-imidazolyl)-3-pyridazinamineCavia porcellus (domestic guinea pig)Potency15.848910
mevalonolactoneCavia porcellus (domestic guinea pig)Potency12.589310
ubp 302Cavia porcellus (domestic guinea pig)Potency6.309610
cgp 43487Cavia porcellus (domestic guinea pig)Potency25.118910
gw 1929Cavia porcellus (domestic guinea pig)Potency20.811410
n-(3-(cyclohexylidene-(1h-imidazol-4-ylmethyl))phenyl)ethanesulfonamideCavia porcellus (domestic guinea pig)Potency6.718220
bay-k-8644, (-)-isomerCavia porcellus (domestic guinea pig)Potency8.922110
b 43Cavia porcellus (domestic guinea pig)Potency22.151020
(8R)-7-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triolCavia porcellus (domestic guinea pig)Potency39.810710
dilazep(2+)Cavia porcellus (domestic guinea pig)Potency10.730920
dihydrexidineCavia porcellus (domestic guinea pig)Potency27.063720
4-(2-(phenylsulfonylamino)ethylthio)-2,6-difluorophenoxyacetamideCavia porcellus (domestic guinea pig)Potency31.622810
gr 103545Cavia porcellus (domestic guinea pig)Potency12.589310
gw2974Cavia porcellus (domestic guinea pig)Potency12.589310
l 750667Cavia porcellus (domestic guinea pig)Potency6.309610
l 162313Cavia porcellus (domestic guinea pig)Potency12.589310
l-165041Cavia porcellus (domestic guinea pig)Potency10.000010
pd 404182Cavia porcellus (domestic guinea pig)Potency5.512320
5-(4-phenylbutoxy)psoralenCavia porcellus (domestic guinea pig)Potency0.100010
sb 222200Cavia porcellus (domestic guinea pig)Potency23.477920
suloctidilCavia porcellus (domestic guinea pig)Potency5.038720
dibenzheptropine citrateCavia porcellus (domestic guinea pig)Potency12.589310
gabexate methanesulfonateCavia porcellus (domestic guinea pig)Potency15.848910
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (trans)-(-)-isomerCavia porcellus (domestic guinea pig)Potency15.848910
1-aminocyclopentane-1,3,4-tricarboxylic acidCavia porcellus (domestic guinea pig)Potency6.309610
am 404Cavia porcellus (domestic guinea pig)Potency5.011910
5-ia-85380Cavia porcellus (domestic guinea pig)Potency29.021220
bay-k-8644Cavia porcellus (domestic guinea pig)Potency0.158510
ro 25-6981Cavia porcellus (domestic guinea pig)Potency15.848910
alx 5407Cavia porcellus (domestic guinea pig)Potency2.511910
omdm-2 cpdCavia porcellus (domestic guinea pig)Potency31.622810
ym 976Cavia porcellus (domestic guinea pig)Potency39.810710
n,n'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamineCavia porcellus (domestic guinea pig)Potency1.995310
aminopurvalanol aCavia porcellus (domestic guinea pig)Potency15.148920
bvt.948Cavia porcellus (domestic guinea pig)Potency25.118910
iem 1460Cavia porcellus (domestic guinea pig)Potency12.589310
Garcinolic acidCavia porcellus (domestic guinea pig)Potency25.118910
bibx 1382bsCavia porcellus (domestic guinea pig)Potency12.589310
3-(diphenylmethylene)-1-[4-(4-phenyl-1-piperazinyl)butyl]pyrrolidine-2,5-dioneCavia porcellus (domestic guinea pig)Potency19.952610
N-[2-(3-methoxyphenyl)-4-[(4-methoxyphenyl)methoxy]-6-quinolinyl]-3-pyridinecarboxamideCavia porcellus (domestic guinea pig)Potency28.183810
sl 327Cavia porcellus (domestic guinea pig)Potency1.584910
3-(1H-benzimidazol-2-yl)-1-[4-(2,4-dimethylphenyl)-1-piperazinyl]-1-propanoneCavia porcellus (domestic guinea pig)Potency19.952610
N-[3-(3,5-dimethyl-1-piperidinyl)propyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamideCavia porcellus (domestic guinea pig)Potency25.118910
LSM-34734Cavia porcellus (domestic guinea pig)Potency19.952610
chlorhexidineCavia porcellus (domestic guinea pig)Potency14.545120
sgd 301-76Cavia porcellus (domestic guinea pig)Potency3.981110
tabimorelinCavia porcellus (domestic guinea pig)Potency19.952610
biie 0246Cavia porcellus (domestic guinea pig)Potency10.000010
l 755507Cavia porcellus (domestic guinea pig)Potency3.162310
nnc 26-9100Cavia porcellus (domestic guinea pig)Potency39.810710
gw0742Cavia porcellus (domestic guinea pig)Potency19.952610
NNC 55-0396 (free base)Cavia porcellus (domestic guinea pig)Potency3.162310
sr 11302Cavia porcellus (domestic guinea pig)Potency28.183810
5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1h-indoleCavia porcellus (domestic guinea pig)Potency28.183810
le 135Cavia porcellus (domestic guinea pig)Potency31.622810
methyl arachidonylfluorophosphonateCavia porcellus (domestic guinea pig)Potency4.466810
2,2,6,6-tetramethylpiperidin-4-yl heptanoateCavia porcellus (domestic guinea pig)Potency31.622810
tetrabenazineCavia porcellus (domestic guinea pig)Potency39.810710
n,n'-dibenzhydrylethane-1,2-diamine dihydrochlorideCavia porcellus (domestic guinea pig)Potency1.000010
4-[[[2-(cyclohexylamino)-3,4-dioxo-1-cyclobutenyl]amino]methyl]-N-(4-ethoxyphenyl)benzamideCavia porcellus (domestic guinea pig)Potency31.622810
N-[5-[2-(5-chloro-2-methylanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]heptanamideCavia porcellus (domestic guinea pig)Potency39.810710
phenylmercuric acetateCavia porcellus (domestic guinea pig)Potency0.316210
thimerosalCavia porcellus (domestic guinea pig)Potency0.631010
nsc 23766Cavia porcellus (domestic guinea pig)Potency12.589310
ro 10-5824Cavia porcellus (domestic guinea pig)Potency25.118910
meclofenamate sodium anhydrousCavia porcellus (domestic guinea pig)Potency1.258910
sodium nitriteCavia porcellus (domestic guinea pig)Potency31.622810
phenytoin sodiumCavia porcellus (domestic guinea pig)Potency39.810710
naproxen sodiumCavia porcellus (domestic guinea pig)Potency39.810710
dicumarolCavia porcellus (domestic guinea pig)Potency0.025110
piroxicamCavia porcellus (domestic guinea pig)Potency16.064410
mobiflexCavia porcellus (domestic guinea pig)Potency2.511910
ethyl 1-benzyl-3-hydroxy-2(5h)-oxopyrrole-4-carboxylateCavia porcellus (domestic guinea pig)Potency8.728220
N-(1H-benzimidazol-2-yl)-1-ethyl-4-hydroxy-2-oxo-3-quinolinecarboxamideCavia porcellus (domestic guinea pig)Potency10.000010
lfm a13Cavia porcellus (domestic guinea pig)Potency7.943310
nu 1025Cavia porcellus (domestic guinea pig)Potency3.981110
rifampinCavia porcellus (domestic guinea pig)Potency31.622810
clozapineCavia porcellus (domestic guinea pig)Potency21.562220
suptopin 2Cavia porcellus (domestic guinea pig)Potency25.118910
2-[(2-oxo-3-indolyl)amino]-N-(2-phenylethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamideCavia porcellus (domestic guinea pig)Potency25.118910
hemateinCavia porcellus (domestic guinea pig)Potency31.622810
norclozapineCavia porcellus (domestic guinea pig)Potency12.589310
2-[(2-methyl-2,3-dihydroindol-1-yl)methyl]-4-oxo-1H-quinazoline-7-carboxylic acid methyl esterCavia porcellus (domestic guinea pig)Potency10.000010
N-(2-furanylmethyl)-3-(2-furanylmethylimino)-1-isoindolamineCavia porcellus (domestic guinea pig)Potency25.118910
ag-879Cavia porcellus (domestic guinea pig)Potency5.095720
1-[4-[[oxo-(7-oxo-4H-isothiazolo[4,3-d]pyrimidin-3-yl)methyl]amino]phenyl]-3-piperidinecarboxylic acid ethyl esterCavia porcellus (domestic guinea pig)Potency39.810710
2-[(dimethylamino)methyl]-4-spiro[1,6-dihydrobenzo[h]quinazoline-5,1'-cyclohexane]oneCavia porcellus (domestic guinea pig)Potency15.848910
2-(diethylaminomethyl)-4-spiro[1,6-dihydrobenzo[h]quinazoline-5,1'-cyclohexane]oneCavia porcellus (domestic guinea pig)Potency15.848910

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
amitriptylineCavia porcellus (domestic guinea pig)IC500.660011
cimetidineCavia porcellus (domestic guinea pig)IC501.020011
cimetidineCavia porcellus (domestic guinea pig)Ki0.302011
clomipramineCavia porcellus (domestic guinea pig)IC500.720011
desipramineCavia porcellus (domestic guinea pig)IC503.800011
doxepinCavia porcellus (domestic guinea pig)IC501.600011
imipramineCavia porcellus (domestic guinea pig)IC501.900011
4-(dimethylamino)-n-(7-(hydroxyamino)-7-oxoheptyl)benzamideCavia porcellus (domestic guinea pig)IC501.620012
mianserinCavia porcellus (domestic guinea pig)IC500.880011
nortriptylineCavia porcellus (domestic guinea pig)IC507.000011
pyroxamideCavia porcellus (domestic guinea pig)IC5010.000012
ranitidineCavia porcellus (domestic guinea pig)Ki0.053711
vorinostatCavia porcellus (domestic guinea pig)IC507.200012
tiotidineCavia porcellus (domestic guinea pig)Ki0.005611
mianserin hydrochlorideCavia porcellus (domestic guinea pig)IC503.800012
aminopotentidineCavia porcellus (domestic guinea pig)Ki0.009811
fr 7534Cavia porcellus (domestic guinea pig)IC500.045011
iodoaminopotentidineCavia porcellus (domestic guinea pig)Ki0.000711
trapoxin aCavia porcellus (domestic guinea pig)IC500.004012
trichostatin aCavia porcellus (domestic guinea pig)IC500.100012
sb-224289Cavia porcellus (domestic guinea pig)Ki1.000012
jnj 7777120Cavia porcellus (domestic guinea pig)Ki3.536919
pranidipineCavia porcellus (domestic guinea pig)IC500.037011
nms p937Cavia porcellus (domestic guinea pig)IC5010.000011

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
histamineCavia porcellus (domestic guinea pig)EC500.807455
cimetidineCavia porcellus (domestic guinea pig)Kd0.419046
formoterol fumarateCavia porcellus (domestic guinea pig)EC500.000511
isoproterenolCavia porcellus (domestic guinea pig)EC500.039811
ranitidineCavia porcellus (domestic guinea pig)Kd0.064611
salmeterol xinafoateCavia porcellus (domestic guinea pig)EC500.000311
histamine dihydrochlorideCavia porcellus (domestic guinea pig)EC501.202312
mifentidineCavia porcellus (domestic guinea pig)Kd0.020637
amthamineCavia porcellus (domestic guinea pig)EC500.190612
ku 1257Cavia porcellus (domestic guinea pig)Kd0.040713
famotidineCavia porcellus (domestic guinea pig)Kd0.100013
methylhistaprodifenCavia porcellus (domestic guinea pig)Kd12.589211
histaprodifenCavia porcellus (domestic guinea pig)Kd34.673711

Drugs with Other Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
7-hydroxy-2-n,n-dipropylaminotetralinCavia porcellus (domestic guinea pig)K0.51.500012
amitriptylineCavia porcellus (domestic guinea pig)K0.50.000512
desipramineCavia porcellus (domestic guinea pig)K0.50.045417
diphenhydramineCavia porcellus (domestic guinea pig)K0.50.004117
doxepinCavia porcellus (domestic guinea pig)K0.50.000117
vanoxerineCavia porcellus (domestic guinea pig)K0.50.009312
haloperidolCavia porcellus (domestic guinea pig)K0.50.215012
ketanserinCavia porcellus (domestic guinea pig)K0.50.001817
loperamideCavia porcellus (domestic guinea pig)K0.52.000017
mazindolCavia porcellus (domestic guinea pig)K0.50.600017
mianserinCavia porcellus (domestic guinea pig)K0.50.000312
nortriptylineCavia porcellus (domestic guinea pig)K0.50.015112
spiperoneCavia porcellus (domestic guinea pig)K0.50.272012
trimeprazineCavia porcellus (domestic guinea pig)K0.50.000212
3-aminofluorantheneCavia porcellus (domestic guinea pig)K0.54.800012
dexchlorpheniramineCavia porcellus (domestic guinea pig)K0.50.000317
butaclamolCavia porcellus (domestic guinea pig)K0.50.147012
rimcazoleCavia porcellus (domestic guinea pig)K0.55.000017
alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanolCavia porcellus (domestic guinea pig)K0.50.180017
atropineCavia porcellus (domestic guinea pig)K0.51.236012
dexchlorpheniramineCavia porcellus (domestic guinea pig)K0.50.020917
sch 23390Cavia porcellus (domestic guinea pig)K0.50.101012
flupenthixolCavia porcellus (domestic guinea pig)K0.50.000917
triprolidineCavia porcellus (domestic guinea pig)K0.50.000117
sk&f-38393Cavia porcellus (domestic guinea pig)K0.52.500012
men 11558Cavia porcellus (domestic guinea pig)KD/Ki0.080011
men 11420Cavia porcellus (domestic guinea pig)KD/Ki0.011511