phenobarbital has been researched along with Sensitivity and Specificity in 52 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to re-evaluate the accuracy of phenobarbital-enhanced hepatobiliary scintigraphy in differentiating biliary atresia from other causes of neonatal cholestasis." | 7.79 | Phenobarbital-enhanced hepatobiliary scintigraphy in the diagnosis of biliary atresia: two decades of experience at a tertiary center. ( Ghelani, S; Kwatra, N; Majd, M; Mohan, P; Narayanan, S; Shalaby-Rana, E, 2013) |
| "The purpose of this study was to re-evaluate the accuracy of phenobarbital-enhanced hepatobiliary scintigraphy in differentiating biliary atresia from other causes of neonatal cholestasis." | 3.79 | Phenobarbital-enhanced hepatobiliary scintigraphy in the diagnosis of biliary atresia: two decades of experience at a tertiary center. ( Ghelani, S; Kwatra, N; Majd, M; Mohan, P; Narayanan, S; Shalaby-Rana, E, 2013) |
| " Phenobarbital caused follicular cell hypertrophy and hyperplasia in the thyroid and centrilobular hypertrophy in the liver, without effects on serum triiodotyronine (T(3)), thyroxine (T(4)) levels." | 3.74 | Standardization of the perchlorate discharge assay for thyroid toxicity testing in rats. ( Coelho-Palermo Cunha, G; van Ravenzwaay, B, 2007) |
| " the LTA by using trypan blue exclusion and to determine the utility of the assay to confirm drug hypersensitivity syndrome (DHS) to sulphonamides (SMX) and aromatic anticonvulsants." | 3.70 | A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes. ( Malkiewicz, IM; Neuman, MG; Shear, NH, 2000) |
| "The ability of diethylnitrosamine (DENA) to initiate and phenobarbital to promote altered-hepatocyte foci and hepatocellular carcinomas in C3H and C3B6F1 (C3H x C57BL/6) mice was compared to the extent of cell proliferation." | 3.68 | Comparison in C3H and C3B6F1 mice of the sensitivity to diethylnitrosamine-initiation and phenobarbital-promotion to the extent of cell proliferation. ( Pereira, MA, 1993) |
| "Phenobarbital was chosen because its value had been demonstrated as a marker of compliance in long-course therapies, any significant departure from steady-state concentrations (achieved with full compliance) indicating one or more missed doses." | 2.69 | Initial evaluation of low-dose phenobarbital as an indicator of compliance with antimalarial drug treatment. ( Feely, M; Fungladda, W; Hay, A; Karbwang, J; Pickard, CE; Shires, S, 1998) |
| " The method has been successfully used to study the pharmacokinetics of levodopa in vivo; the values of the pharmacokinetics parameters Cmax, AUC(0-t) and Tmax were 16." | 1.33 | Microdialysis sampling and high-performance liquid chromatography with chemiluminescence detection for in-vivo on-line determination and study of the pharmacokinetics of levodopa in blood. ( Deyong, H; Funan, C; Yingxue, Z; Zhujun, Z, 2005) |
| "Phenytoin assays were evaluated using an additional set of samples from patients with abnormal renal function." | 1.31 | Performance characteristics of four immunoassays for antiepileptic drugs on the IMMULITE 2000 automated analyzer. ( Annesley, TM; Frank, EL; Juenke, J; Roberts, WL; Schwarz, EL, 2002) |
| " At extremely long half-lives, relative to the period of dosing being monitored, sensitivity approaches 100% if measurement error is in the 1-2% range." | 1.30 | A computer model for the measurement of compliance using a dual tracer technique. ( McDonald, J; Shine, D, 1997) |
| "Phenobarbital was administered orally to five male subjects and urine was collected for a period of 96-108 h." | 1.30 | High-performance liquid chromatographic analysis of phenobarbital and phenobarbital metabolites in human urine. ( Paibir, SG; Soine, WH, 1997) |
| " Male and female Sprague-Dawley (CD) rats were dosed with either pregnenolone-16alpha-carbonitrile (PCN; 50 mg/kg per day for 5 days), phenobarbital (PB; 100 mg/kg per day for 4 days), beta-naphthoflavone (betaNF; 100 mg/kg per day for 3 days), clofibrate (CF; 300 mg/kg per day for 14 days), isoniazid (ISO; 100 mg/kg per day for 3 days), or dexamethasone (DEX; 50 mg/kg per day for 4 days)." | 1.30 | Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP3A activity in rat hepatic microsomes. ( Amacher, DE; Schomaker, SJ, 1998) |
| "Bilirubin interference was less than 10." | 1.30 | Comparison of the serum barbiturate fluorescence polarization immunoassay by the COBAS INTEGRA to a GC/MS method. ( Cannon, RD; Gock, SB; Jentzen, JJ; Wong, SH, 1999) |
| "A capillary electrophoresis method was developed to separate and quantitate ephedrine (ED), theophylline (TP) and phenobarbital (PB) in a tablet dosage form." | 1.30 | Determination of ephedrine, theophylline and phenobarbital in a tablet dosage form by capillary electrophoresis. ( Haque, A; Stewart, JT; Xu, X, 1999) |
| "Attacks of sustained dystonia of the limbs and trunk can be initiated by handling or mild environmental stimuli (e." | 1.29 | Alterations in pharmacological sensitivity of GABAergic but not dopaminergic and glutamatergic systems during ontogenesis in dystonic mutant hamsters. ( Löscher, W; Richter, A, 1993) |
| "Phenobarbital pretreatment of the rats did not affect any of these kinetic parameters." | 1.28 | Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol. ( Dunbar, D; Fraser, JM; Kaminsky, LS; Seaman, M, 1992) |
| "Mefenamic acid (MA) is a nonsteroidal antiinflammatory analgesic agent widely used clinically." | 1.28 | Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma. ( Cheymol, G; Lebot, M; Poirier, JM, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 24 (46.15) | 18.2507 |
| 2000's | 23 (44.23) | 29.6817 |
| 2010's | 5 (9.62) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ji, Z | 1 |
| Settivari, RS | 1 |
| LeBaron, MJ | 1 |
| Kwatra, N | 1 |
| Shalaby-Rana, E | 1 |
| Narayanan, S | 1 |
| Mohan, P | 1 |
| Ghelani, S | 1 |
| Majd, M | 1 |
| Alagandula, R | 1 |
| Zhou, X | 1 |
| Guo, B | 1 |
| la Marca, G | 1 |
| Malvagia, S | 1 |
| Filippi, L | 1 |
| Luceri, F | 1 |
| Moneti, G | 1 |
| Guerrini, R | 1 |
| Tai, SS | 1 |
| Yeh, CY | 1 |
| Phinney, KW | 1 |
| Rani, S | 1 |
| Malik, AK | 1 |
| Singh, B | 1 |
| Frank, EL | 1 |
| Schwarz, EL | 1 |
| Juenke, J | 1 |
| Annesley, TM | 1 |
| Roberts, WL | 1 |
| Li, Y | 1 |
| Zhao, D | 1 |
| Zhu, C | 1 |
| Wang, L | 1 |
| Xu, J | 2 |
| Bushel, PR | 1 |
| Hamadeh, HK | 1 |
| Bennett, L | 1 |
| Green, J | 1 |
| Ableson, A | 1 |
| Misener, S | 1 |
| Afshari, CA | 1 |
| Paules, RS | 1 |
| El-Gindy, A | 2 |
| Emara, S | 1 |
| Hadad, GM | 1 |
| Tutor-Crespo, MJ | 1 |
| Hermida, J | 1 |
| Tutor, JC | 1 |
| Hoh, BL | 1 |
| Rabinov, JD | 1 |
| Pryor, JC | 1 |
| Hirsch, JA | 1 |
| Dooling, EC | 1 |
| Ogilvy, CS | 1 |
| Ringel, M | 1 |
| von Mach, MA | 1 |
| Santos, R | 1 |
| Feilen, PJ | 1 |
| Brulport, M | 1 |
| Hermes, M | 1 |
| Bauer, AW | 1 |
| Schormann, W | 1 |
| Tanner, B | 1 |
| Schön, MR | 1 |
| Oesch, F | 1 |
| Hengstler, JG | 1 |
| Funan, C | 1 |
| Zhujun, Z | 1 |
| Yingxue, Z | 1 |
| Deyong, H | 1 |
| Patil, KM | 1 |
| Bodhankar, SL | 1 |
| Amacher, DE | 2 |
| Adler, R | 1 |
| Herath, A | 1 |
| Townsend, RR | 1 |
| Zhao, Y | 1 |
| Rui, JZ | 1 |
| Li, JH | 1 |
| Xiang, BR | 1 |
| Cantú, MD | 1 |
| Toso, DR | 1 |
| Lacerda, CA | 1 |
| Lanças, FM | 1 |
| Carrilho, E | 1 |
| Queiroz, ME | 2 |
| Sevilla, A | 1 |
| Howman-Giles, R | 1 |
| Saleh, H | 1 |
| Trpezanovski, J | 1 |
| Concannon, R | 1 |
| Williams, K | 1 |
| Chung, D | 1 |
| Uren, R | 1 |
| Coelho-Palermo Cunha, G | 1 |
| van Ravenzwaay, B | 1 |
| Vermeij, TA | 1 |
| Edelbroek, PM | 1 |
| Queiroz, RH | 1 |
| Bertucci, C | 1 |
| Malfará, WR | 1 |
| Dreossi, SA | 1 |
| Chaves, AR | 1 |
| Valério, DA | 1 |
| Naranjo, CA | 1 |
| Kwok, MC | 1 |
| Lanctôt, KL | 1 |
| Zhao, HP | 1 |
| Spielberg, SP | 1 |
| Shear, NH | 2 |
| Knickle, LC | 1 |
| Philpot, RM | 1 |
| Bend, JR | 1 |
| Pereira, MA | 1 |
| Richter, A | 1 |
| Löscher, W | 1 |
| Aoki, K | 1 |
| Yoshida, T | 1 |
| Kuroiwa, Y | 1 |
| Lin, WY | 1 |
| Lin, CC | 1 |
| Changlai, SP | 1 |
| Shen, YY | 1 |
| Wang, SJ | 1 |
| Shine, D | 1 |
| McDonald, J | 1 |
| Paibir, SG | 1 |
| Soine, WH | 1 |
| Schomaker, SJ | 1 |
| Thacker, DL | 1 |
| Abernethy, DR | 1 |
| Raines, A | 1 |
| Flockhart, DA | 1 |
| Runge-Morris, M | 1 |
| Rose, K | 1 |
| Falany, CN | 1 |
| Kocarek, TA | 1 |
| Karbwang, J | 1 |
| Fungladda, W | 1 |
| Pickard, CE | 1 |
| Shires, S | 1 |
| Hay, A | 1 |
| Feely, M | 1 |
| Ceccato, A | 1 |
| Boulanger, B | 1 |
| Chiap, P | 1 |
| Hubert, P | 1 |
| Crommen, J | 1 |
| Sakuma, T | 1 |
| Ohtake, M | 1 |
| Katsurayama, Y | 1 |
| Jarukamjorn, K | 1 |
| Nemoto, N | 1 |
| Moriyama, M | 1 |
| Yamashita, S | 1 |
| Domoto, H | 1 |
| Furuno, K | 1 |
| Araki, H | 1 |
| Gomita, Y | 1 |
| Cannon, RD | 1 |
| Wong, SH | 1 |
| Gock, SB | 1 |
| Jentzen, JJ | 1 |
| Martín-Biosca, Y | 1 |
| Sagrado, S | 1 |
| Villanueva-Camãnas, RM | 1 |
| Medina-Hernández, MJ | 1 |
| Haque, A | 1 |
| Xu, X | 1 |
| Stewart, JT | 1 |
| Tang, C | 1 |
| Kassahun, K | 1 |
| McIntosh, IS | 1 |
| Brunner, J | 1 |
| Rodrigues, AD | 1 |
| Neuman, MG | 1 |
| Malkiewicz, IM | 1 |
| Gerhold, D | 1 |
| Lu, M | 1 |
| Austin, C | 1 |
| Caskey, CT | 1 |
| Rushmore, T | 1 |
| Gupta, DK | 1 |
| Charles, AR | 1 |
| Srinivas, M | 1 |
| Dave, S | 1 |
| Bal, CS | 1 |
| Danilova, NP | 1 |
| Beckman, NI | 1 |
| Yazynin, SA | 1 |
| Vasilov, RG | 1 |
| Kaminsky, LS | 1 |
| Fraser, JM | 1 |
| Seaman, M | 1 |
| Dunbar, D | 1 |
| Poirier, JM | 1 |
| Lebot, M | 1 |
| Cheymol, G | 1 |
| Salmain, M | 1 |
| Vessières, A | 1 |
| Brossier, P | 1 |
| Butler, IS | 1 |
| Jaouen, G | 1 |
| Fukui, Y | 1 |
| Yamamoto, A | 1 |
| Masaki, R | 1 |
| Miyauchi, K | 1 |
| Tashiro, Y | 1 |
| Jandreski, MA | 1 |
| Shah, JC | 1 |
| Garbincius, J | 1 |
| Bermes, EW | 1 |
| Fairchild, L | 1 |
| Wong, E | 1 |
| Li, TM | 1 |
| Litman, DJ | 1 |
1 trial available for phenobarbital and Sensitivity and Specificity
| Article | Year |
|---|---|
Initial evaluation of low-dose phenobarbital as an indicator of compliance with antimalarial drug treatment.
Topics: Adolescent; Adult; Antimalarials; Biomarkers; Female; Humans; Malaria, Falciparum; Male; Middle Aged | 1998 |
51 other studies available for phenobarbital and Sensitivity and Specificity
| Article | Year |
|---|---|
Pilot studies evaluating the nongenotoxic rodent carcinogens phenobarbital and clofibrate in the rat Pig-a assay.
Topics: Animals; Biological Assay; Carcinogens; Clofibrate; Glycosylphosphatidylinositols; Liver; Liver Neop | 2019 |
Phenobarbital-enhanced hepatobiliary scintigraphy in the diagnosis of biliary atresia: two decades of experience at a tertiary center.
Topics: Biliary Atresia; Causality; Cholestasis; District of Columbia; Female; Humans; Image Enhancement; In | 2013 |
A dilute-and-shoot flow-injection tandem mass spectrometry method for quantification of phenobarbital in urine.
Topics: Chromatography, Liquid; Humans; Linear Models; Phenobarbital; Reproducibility of Results; Sensitivit | 2017 |
A new rapid micromethod for the assay of phenobarbital from dried blood spots by LC-tandem mass spectrometry.
Topics: Anticonvulsants; Biological Assay; Blood Chemical Analysis; Blood Specimen Collection; Calibration; | 2009 |
Development and validation of a reference measurement procedure for certification of phenytoin, phenobarbital, lamotrigine, and topiramate in human serum using isotope-dilution liquid chromatography/tandem mass spectrometry.
Topics: Anticonvulsants; Chromatography, Reverse-Phase; Fructose; Humans; Indicator Dilution Techniques; Lam | 2011 |
Novel micro-extraction by packed sorbent procedure for the liquid chromatographic analysis of antiepileptic drugs in human plasma and urine.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Humans; Oxcarbazepine; Phenobarbital; Phenyt | 2012 |
Performance characteristics of four immunoassays for antiepileptic drugs on the IMMULITE 2000 automated analyzer.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Cross Reactions; Drug Monitori | 2002 |
Determination of proteins at nanogram levels by their quenching effect on the chemiluminescence reaction between luminol and hydrogen peroxide with manganese-tetrasulfonatophthalocyanine as a new catalyst.
Topics: Animals; Blood Proteins; Cattle; Humans; Hydrogen Peroxide; Immunoglobulin gamma-Chains; Indoles; Lu | 2002 |
Computational selection of distinct class- and subclass-specific gene expression signatures.
Topics: Algorithms; Animals; Base Sequence; Cluster Analysis; DNA Mutational Analysis; Feasibility Studies; | 2002 |
Determination of two ternary mixtures containing phenobarbitone by second derivative of the ratio spectrum-zero-crossing and HPLC methods.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Mephobarbital; Papaverine; Phenobarbital; Phe | 2003 |
Activation of serum aminotransferases by pyridoxal-5' -phosphate in epileptic patients treated with anticonvulsant drugs.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Carbamazepine; Drug Therapy, Combination; | 2004 |
Persistent nonfused segments of the basilar artery: longitudinal versus axial nonfusion.
Topics: Adult; Angiography, Digital Subtraction; Anticonvulsants; Basilar Artery; Cerebellum; Cerebral Angio | 2004 |
Hepatocytes cultured in alginate microspheres: an optimized technique to study enzyme induction.
Topics: Alginates; Animals; Cell Culture Techniques; Cells, Cultured; Coculture Techniques; Cytochrome P-450 | 2005 |
Microdialysis sampling and high-performance liquid chromatography with chemiluminescence detection for in-vivo on-line determination and study of the pharmacokinetics of levodopa in blood.
Topics: Chromatography, High Pressure Liquid; Ferricyanides; Levodopa; Luminescence; Microdialysis; Phenobar | 2005 |
Simultaneous determination of lamotrigine, phenobarbitone, carbamazepine and phenytoin in human serum by high-performance liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; | 2005 |
HPLC and chemometric assisted spectrophotometric methods for simultaneous determination of diprophylline, phenobarbitone and papaverine hydrochloride.
Topics: Bronchodilator Agents; Chromatography, High Pressure Liquid; Dyphylline; Papaverine; Pharmaceutical | 2005 |
Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy.
Topics: 1-Naphthylisothiocyanate; Acetaminophen; Animals; Biomarkers; Chemical and Drug Induced Liver Injury | 2005 |
[Rapid analysis of antiepileptic drugs in human plasma by micellar electrokinetic capillary chromatography].
Topics: Anticonvulsants; Buffers; Carbamazepine; Chromatography, Micellar Electrokinetic Capillary; Clonazep | 2006 |
Optimization of solid-phase microextraction procedures for the determination of tricyclic antidepressants and anticonvulsants in plasma samples by liquid chromatography.
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Chromatography, Liq | 2006 |
Hepatobiliary scintigraphy with SPECT in infancy.
Topics: Biliary Atresia; Female; Humans; Infant; Infant, Newborn; Liver Diseases; Male; Phenobarbital; Retro | 2007 |
Standardization of the perchlorate discharge assay for thyroid toxicity testing in rats.
Topics: Animals; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Hyperplasia; Hypertrophy; Iodine Radioi | 2007 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure | 2007 |
Quantification of carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbital in plasma samples by stir bar-sorptive extraction and liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Phenobarbital; Phenyto | 2008 |
Enhanced differential diagnosis of anticonvulsant hypersensitivity reactions by an integrated Bayesian and biochemical approach.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Bayes Theorem; Carbamazepine; Cell Death; Child; Diagnosis | 1994 |
N-aralkylated derivatives of 1-aminobenzotriazole are potent isozyme- and lung-selective mechanism-based inhibitors of guinea pig cytochrome P-450 in vivo.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; | 1994 |
Comparison in C3H and C3B6F1 mice of the sensitivity to diethylnitrosamine-initiation and phenobarbital-promotion to the extent of cell proliferation.
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Cell Division; Diethylnitrosamine; Female; Liver; Liver | 1993 |
Alterations in pharmacological sensitivity of GABAergic but not dopaminergic and glutamatergic systems during ontogenesis in dystonic mutant hamsters.
Topics: Aging; Aminooxyacetic Acid; Animals; Cricetinae; Diazepam; Dopamine Antagonists; Dystonia; Mesocrice | 1993 |
Forensic immunochemistry.
Topics: Central Nervous System Agents; Cocaine; Enzyme-Linked Immunosorbent Assay; Forensic Medicine; Humans | 1996 |
Comparison technetium of Tc-99m disofenin cholescintigraphy with ultrasonography in the differentiation of biliary atresia from other forms of neonatal jaundice.
Topics: Biliary Atresia; Cholestyramine Resin; Diagnosis, Differential; Female; Humans; Imino Acids; Infant; | 1997 |
A computer model for the measurement of compliance using a dual tracer technique.
Topics: Anti-Arrhythmia Agents; Anticonvulsants; Computer Simulation; Digitoxin; Drug Monitoring; Half-Life; | 1997 |
High-performance liquid chromatographic analysis of phenobarbital and phenobarbital metabolites in human urine.
Topics: Adult; Chromatography, High Pressure Liquid; Glucuronates; Humans; Male; Middle Aged; Phenobarbital; | 1997 |
Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP3A activity in rat hepatic microsomes.
Topics: Animals; Antibodies; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Biomarkers; Clofibrate; Cyt | 1998 |
Method for the determination of 5,5-diphenylbarbituric acid and its separation from 1,3-dimethoxymethyl-5,5-diphenylbarbituric acid in plasma by high-performance liquid chromatography.
Topics: Animals; Anticonvulsants; Barbiturates; Chromatography, High Pressure Liquid; Dogs; Evaluation Studi | 1998 |
Differential regulation of individual sulfotransferase isoforms by phenobarbital in male rat liver.
Topics: Animals; Blotting, Northern; Enzyme Induction; Gene Expression Regulation, Enzymologic; Isoenzymes; | 1998 |
Simultaneous determination of methylphenobarbital enantiomers and phenobarbital in human plasma by on-line coupling of an achiral precolumn to a chiral liquid chromatographic column.
Topics: Chromatography, Liquid; Humans; Mephobarbital; Phenobarbital; Reproducibility of Results; Sensitivit | 1998 |
Induction of CYP1A2 by phenobarbital in the livers of aryl hydrocarbon-responsive and -nonresponsive mice.
Topics: Animals; Carcinogens; Cytochrome P-450 CYP1A2; Enzyme Induction; Female; Male; Mice; Mice, Inbred AK | 1999 |
Determination of plasma phenobarbital concentration by high-performance liquid chromatography in rat offspring.
Topics: Animals; Animals, Newborn; Calibration; Chromatography, High Pressure Liquid; Female; Milk; Phenobar | 1999 |
Comparison of the serum barbiturate fluorescence polarization immunoassay by the COBAS INTEGRA to a GC/MS method.
Topics: Barbiturates; Bilirubin; Fluorescence Polarization Immunoassay; Gas Chromatography-Mass Spectrometry | 1999 |
Determination of phenobarbital in plasma by micellar liquid chromatography.
Topics: Chromatography, Liquid; Humans; Micelles; Phenobarbital; Reference Standards; Sensitivity and Specif | 2000 |
Determination of ephedrine, theophylline and phenobarbital in a tablet dosage form by capillary electrophoresis.
Topics: Calibration; Drug Combinations; Electrophoresis, Capillary; Ephedrine; Hydrogen-Ion Concentration; P | 1999 |
Simultaneous determination of urinary free cortisol and 6beta-hydroxycortisol by liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry and its application for estimating hepatic CYP3A induction.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Atmospheric Pressure; Chromatography, High Pressure Liquid; | 2000 |
A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes.
Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Case-Control Studies; Cell Surviva | 2000 |
Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays.
Topics: Animals; Clofibrate; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Evaluation, Preclinical; En | 2001 |
Betamethasone in plus phenobarbitone prior to hepatobiliary scintigraphy increases diagnostic accuracy in infants with jaundice.
Topics: Betamethasone; Cholestasis, Extrahepatic; Diagnosis, Differential; Female; Humans; Infant; Infant, N | 2001 |
Fast filtration enzyme immunoassay for haptens.
Topics: Animals; Antibodies, Monoclonal; Digoxin; Filtration; Haptens; Horseradish Peroxidase; Humans; Immun | 1992 |
Rat liver metabolism and toxicity of 2,2,2-trifluoroethanol.
Topics: Acetaldehyde; Animals; Antibodies, Monoclonal; Biotransformation; Chemical and Drug Induced Liver In | 1992 |
Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma.
Topics: Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Hydrogen-Ion Concentration; Indomethacin; | 1992 |
Carbonylmetalloimmunoassay (CMIA) a new type of non-radioisotopic immunoassay. Principles and application to phenobarbital assay.
Topics: Cross Reactions; Fourier Analysis; Organometallic Compounds; Phenobarbital; Radioimmunoassay; Refere | 1992 |
Quantitative immunocytochemical analysis of the induction of cytochrome P450IIB in rat hepatocytes.
Topics: Acrylic Resins; Animals; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Enzyme Induction; Fr | 1992 |
Clinical evaluation of five therapeutic drugs using dry film multilayer technology on the OPUS immunoassay system.
Topics: Carbamazepine; Evaluation Studies as Topic; Humans; Immunoassay; Pharmaceutical Preparations; Phenob | 1991 |
Phenobarbital monitoring in whole blood with a quantitative noninstrumented test.
Topics: Drug Monitoring; Humans; Immunoenzyme Techniques; Phenobarbital; Reference Values; Reproducibility o | 1991 |