mefenamic acid has been researched along with Sensitivity and Specificity in 10 studies
Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The applicability of this method for pharmacokinetic studies has been established after successful application during a 12-subject bioavailabity study." | 1.38 | A high performance liquid chromatography-tandem mass spectrometric method for the determination of mefenamic acid in human plasma: application to pharmacokinetic study. ( Bhavsar, R; Dhaneshwar, S; Mahadik, M, 2012) |
| "Naproxen was used as internal standard." | 1.34 | Determination of non-steroidal anti-inflammatory drugs in pharmaceuticals and human serum by dual-mode gradient HPLC and fluorescence detection. ( Bouajila, J; Boyer, A; Couderc, F; Ibrahim, H; Nepveu, F, 2007) |
| "Mefenamic acid (MA) is a nonsteroidal antiinflammatory analgesic agent widely used clinically." | 1.28 | Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma. ( Cheymol, G; Lebot, M; Poirier, JM, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhavesh, D | 1 |
| Shah, S | 1 |
| Madrakian, T | 1 |
| Afkhami, A | 1 |
| Mohammadnejad, M | 1 |
| Cooper, SA | 1 |
| Desjardins, PJ | 1 |
| Mahadik, M | 1 |
| Dhaneshwar, S | 1 |
| Bhavsar, R | 1 |
| Zhang, X | 1 |
| Gong, Z | 1 |
| Espinosa-Mansilla, A | 1 |
| Muñoz de la Peña, A | 1 |
| Cañada-Cañada, F | 1 |
| González Gómez, D | 1 |
| Liu, L | 1 |
| Song, J | 1 |
| Lin, PC | 1 |
| Tseng, MC | 1 |
| Su, AK | 1 |
| Chen, YJ | 1 |
| Lin, CC | 1 |
| Ibrahim, H | 1 |
| Boyer, A | 1 |
| Bouajila, J | 1 |
| Couderc, F | 1 |
| Nepveu, F | 1 |
| Poirier, JM | 1 |
| Lebot, M | 1 |
| Cheymol, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Analgesic Efficacy of Preoperative Oral Administration of Dexketoprofen Trometamol in Third Molar Surgery, Compared to Postoperative Administration[NCT02380001] | Phase 4 | 60 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| A Full-Factorial, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Single-Dose Efficacy and Safety Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen, and Naproxen Sodium in Postoperative Dental Pain[NCT05761574] | Phase 3 | 440 participants (Anticipated) | Interventional | 2023-05-22 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 other studies available for mefenamic acid and Sensitivity and Specificity
| Article | Year |
|---|---|
Determination of fenofibric acid in human plasma by ultra performance liquid chromatography-electrospray ionization mass spectrometry: application to a bioequivalence study.
Topics: Calibration; Chromatography, High Pressure Liquid; Drug Stability; Fenofibrate; Humans; Least-Square | 2009 |
Second-order advantage applied to simultaneous spectrofluorimetric determination of paracetamol and mefenamic acid in urine samples.
Topics: Acetaminophen; Humans; Hydrogen-Ion Concentration; Least-Squares Analysis; Mefenamic Acid; Multivari | 2009 |
The value of the dental impaction pain model in drug development.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human | 2010 |
The value of the dental impaction pain model in drug development.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human | 2010 |
The value of the dental impaction pain model in drug development.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human | 2010 |
The value of the dental impaction pain model in drug development.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human | 2010 |
A high performance liquid chromatography-tandem mass spectrometric method for the determination of mefenamic acid in human plasma: application to pharmacokinetic study.
Topics: Acetates; Anticoagulants; Area Under Curve; Chromatography, High Pressure Liquid; Diclofenac; Drug S | 2012 |
Fluorescent transgenic zebrafish Tg(nkx2.2a:mEGFP) provides a highly sensitive monitoring tool for neurotoxins.
Topics: Acetaminophen; Animals; Animals, Genetically Modified; Atenolol; Atrazine; Axons; Central Nervous Sy | 2013 |
Determinations of fluoroquinolones and nonsteroidal anti-inflammatory drugs in urine by extractive spectrophotometry and photoinduced spectrofluorimetry using multivariate calibration.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry Techniques, Analytical; Ciprofloxacin; Diclofenac | 2005 |
Voltammetric determination of mefenamic acid at lanthanum hydroxide nanowires modified carbon paste electrodes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calibration; Carbon; Electrochemistry; Electrodes; Electrol | 2006 |
Functionalized magnetic nanoparticles for small-molecule isolation, identification, and quantification.
Topics: Flufenamic Acid; Humans; Ketoprofen; Macrolides; Magnetics; Mannose; Mefenamic Acid; Molecular Struc | 2007 |
Determination of non-steroidal anti-inflammatory drugs in pharmaceuticals and human serum by dual-mode gradient HPLC and fluorescence detection.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromatography, High Pressure Liquid; Drug Combina | 2007 |
Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma.
Topics: Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Hydrogen-Ion Concentration; Indomethacin; | 1992 |