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Histone deacetylase 8
A histone deacetylase 8 that is encoded in the genome of mouse. [OMA:Q8VH37, PRO:DNx]
Synonyms
HD8;
EC 3.5.1.98
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (1)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| trichostatin a | Mus musculus (house mouse) | IC50 | 0.0207 | 2 | 2 |
Synthesis and histone deacetylase inhibitory activity of cyclic tetrapeptides containing a retrohydroxamate as zinc ligand.Bioorganic & medicinal chemistry letters, , May-17, Volume: 14, Issue:10, 2004
Histone deacetylase inhibitors.Journal of medicinal chemistry, , Nov-20, Volume: 46, Issue:24, 2003