quinapyramine: RN given refers to hydride; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 122993 |
| CHEMBL ID | 1398609 |
| SCHEMBL ID | 291197 |
| SCHEMBL ID | 14286196 |
| MeSH ID | M0047436 |
| Synonym |
|---|
| nsc-48223 |
| NCI60_004145 |
| n6-(2-imino-1,6-dimethyl-1,2-dihydro-4-pyrimidinyl)-1,2-dimethyl-15-quinoline-4,6-diamine |
| antrycide |
| quinolinium, 4-amino-6-[(2-amino-1,6-dimethyl-4(1h)-pyrimidinylidene)amino]-1,2-dimethyl- |
| 23609-65-6 |
| 6-[(e)-(2-amino-1,6-dimethyl-pyrimidin-4-ylidene)amino]-1,2-dimethyl-quinolin-1-ium-4-amine |
| quinapyramine |
| NSC48223 , |
| NCGC00013591 |
| NCI48223 |
| 4-amino-6-((2-amino-1,6-dimethyl-4-pyrimidinyl)amino)-1-methylquinaldinium ion |
| quinolinium, 4-amino-6-((2-amino-1,6-dimethyl-4(1h)-pyrimidinylidene)amino)-1,2-dimethyl-, conjugate monoacid |
| NCISTRUC2_001482 |
| NCISTRUC1_001223 |
| NCGC00096704-01 |
| CCG-36923 |
| NCGC00013591-02 |
| quinapyramine cation |
| 20493-41-8 |
| quinapyramine ion |
| b2nt1100wr , |
| unii-b2nt1100wr |
| quinolinium, 4-amino-6-((1,2-dihydro-2-imino-1,6-dimethyl-4-pyrimidinyl)amino)-1,2-dimethyl- |
| quinapyramine [mi] |
| 1082114-38-2 |
| SCHEMBL291197 |
| SCHEMBL14286196 |
| CHEMBL1398609 |
| 6-[(2-amino-1,6-dimethylpyrimidin-4-ylidene)amino]-1,2-dimethylquinolin-1-ium-4-amine |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 7.9433 | 0.0126 | 10.6917 | 88.5700 | AID887 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 0.7943 | 0.2818 | 9.7212 | 35.4813 | AID2326 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 50 (62.50) | 18.7374 |
| 1990's | 13 (16.25) | 18.2507 |
| 2000's | 5 (6.25) | 29.6817 |
| 2010's | 10 (12.50) | 24.3611 |
| 2020's | 2 (2.50) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 3 (3.70%) | 6.00% |
| Case Studies | 1 (1.23%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 77 (95.06%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Article | Year |
|---|---|
| Cytotoxicity and genotoxicity of a trypanocidal drug quinapyramine sulfate loaded-sodium alginate nanoparticles in mammalian cells. International journal of biological macromolecules, Volume: 88 | 2016 |
| In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi. Veterinary parasitology, May-11, Volume: 169, Issue: 3-4 | 2010 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |
| Article | Year |
|---|---|
| In vivo and in vitro sensitivity of Trypanosoma evansi and T. equiperdum to diminazene, suramin, MelCy, quinapyramine and isometamidium. Acta tropica, Volume: 50, Issue: 2 | 1991 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |
| Article | Year |
|---|---|
| Studies of quinapyramine-resistance of Trypanosoma brucei evansi in China. Acta tropica, Volume: 116, Issue: 3 | 2010 |
| Development and application of an antibody-ELISA to follow up a Trypanosoma evansi outbreak in a dromedary camel herd in France. Veterinary parasitology, Jun-10, Volume: 162, Issue: 3-4 | 2009 |
| Resistance to drug by different isolates Trypanosoma evansi in China. Acta tropica, Volume: 90, Issue: 3 | 2004 |
| Drug resistance in Sudanese Trypanosoma evansi. Veterinary parasitology, Jan-28, Volume: 80, Issue: 4 | 1999 |
| In vivo and in vitro sensitivity of Trypanosoma evansi and T. equiperdum to diminazene, suramin, MelCy, quinapyramine and isometamidium. Acta tropica, Volume: 50, Issue: 2 | 1991 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |