Imidacloprid is a neonicotinoid insecticide that is widely used to control a variety of insect pests. It is a synthetic analogue of nicotine, and it works by acting as an agonist at nicotinic acetylcholine receptors in the insect nervous system. Imidacloprid is synthesized from nicotinic acid and 6-chloropyridine-3-carbonitrile through a series of steps. It is a highly effective insecticide, and it has been shown to be effective against a wide range of insect pests, including aphids, whiteflies, and leafhoppers. Imidacloprid has also been shown to be effective in controlling insect pests in crops such as cotton, soybeans, corn, and wheat. Imidacloprid is a highly effective insecticide. It is also very persistent in the environment, and it has been detected in water, soil, and wildlife. Imidacloprid has been linked to adverse effects on bees, birds, and other wildlife. It has also been implicated in the decline of honeybee populations. Imidacloprid is studied because it is a widely used insecticide, and because of its potential to harm wildlife and the environment. Studies are conducted to better understand its fate in the environment, and its effects on non-target organisms.'
(E)-imidacloprid : The E-isomer of imidacloprid. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
imidacloprid: systemic & contact insecticide exhibiting low mammalian toxicity; structure given in first source; it is one of the neonicotinoid insecticides, which acts as an antagonist by binding to postsynaptic nicotinic receptors in the insect central nervous system [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
imidacloprid : An imidazolidine that is N-nitroimidazolidin-2-imine bearing a (6-chloro-3-pyridinyl)methyl substituent at position 1. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 86287518 |
| CHEBI ID | 39168 |
| CHEBI ID | 5870 |
| SCHEMBL ID | 22278 |
| MeSH ID | M0219479 |
| PubMed CID | 86418 |
| MeSH ID | M0219479 |
| PubMed CID | 135527764 |
| MeSH ID | M0219479 |
| Synonym |
|---|
| imidacloprid (old rn) |
| premise 75 |
| 2-imidazolidinimine, 1-((6-chloro-3-pyridinyl)methyl)-n-nitro- |
| merit |
| 1-(6-chloro-3-pyridylmethyl)-n-nitroimidazolidin-2-ylideneamine |
| confidor |
| provado |
| epa pesticide chemical code 129099 |
| admire |
| ntn 33893-240fs |
| hsdb 7373 |
| merit (insecticide) |
| cp 1 |
| bay-ntn 33893 |
| ntn 33893 |
| advantage flea adulticide |
| confidor sl |
| 1h-imidazol-2-amine, 1-((6-chloro-3-pyridinyl)methyl)-4,5-dihydro-n-nitro- |
| imidacloprid [iso] |
| gaucho |
| 1h-imidazol-2-amine, 4,5-dihydro-1-((6-chloro-3-pyridinyl)methyl)-n-nitro- |
| confidor 200 sl |
| (e)-imidacloprid |
| CHEBI:39168 |
| 1-((6-chloro-3-pyridyl)methyl)-n-nitro-2-imidazolidinimine |
| 1-((6-chloro-3-pyridinyl)methyl)-n-nitro-2-imidazolidinimine |
| (2e)-1-[(6-chloropyridin-3-yl)methyl]-n-nitroimidazolidin-2-imine |
| CHEBI:5870 , |
| NCGC00163736-01 |
| NCGC00163736-02 |
| inchi=1/c9h10cln5o2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5h,3-4,6h2,(h,11,13) |
| ywtyjopnnqfbpc-uhfffaoysa- |
| AKOS005622077 |
| NCGC00163736-03 |
| admire 2f |
| bayer advanced season-long grub control |
| confidor 240 o-teq |
| baimieshi |
| trimax pro |
| alias 2f |
| kohinor |
| agst 03001 |
| macho max |
| preventol tm |
| imicide |
| alias |
| grubex |
| hachikusan |
| coretect |
| confidate |
| premise (insecticide) |
| couraze |
| admire pro |
| confidor 200 o-teq |
| ec 428-040-8 |
| meritgreen |
| senator (neonicotinoid) |
| gaucho grande |
| 1-(6-chloropyridin-3-ylmethyl)-n-nitroimidazolidin-2-ylidenamine |
| gaucho 600fs |
| ae-f 106464-00gr01b0 |
| advise |
| ccris 9318 |
| 3bn7m937v8 , |
| proagro |
| confidor 200sl |
| couraze max |
| aef 106464 |
| confidor 70wg |
| mallet 2f |
| unii-3bn7m937v8 |
| marathon ii |
| tox21_113358 |
| NCGC00254930-01 |
| tox21_301028 |
| cas-138261-41-3 |
| dtxcid3012442 |
| dtxsid5032442 , |
| tox21_111298 |
| genesis |
| SCHEMBL22278 |
| NCGC00163736-04 |
| tox21_111298_1 |
| LD-0259 |
| imidaclopride |
| 2-{1-[(6-chloro-3-pyridyl)methyl]tetrahydro-2h-imidazol-2-yliden}-1-oxo-1-hydraziniumolate |
| bayer brand of imidacloprid |
| 1-[(6-chloro-3-pyridinyl)methyl]-4,5-dihydro-n-nitro-1h-imidazol-2-amine, 9ci |
| HY-B0838 |
| CS-6904 |
| DB11421 |
| (2e)-1-[(6-chloropyridin-3-yl)methyl]-n-nitroimidazolidin-2-imine (imidachloprid) |
| imidachloprid |
| AMY8616 |
| (2e)-1-[(6-chloro-3-pyridinyl)methyl]-n-nitro-2- imidazolidinimine |
| (ne)-n-[1-[(6-chloropyridin-3-yl)methyl]imidazolidin-2-ylidene]nitramide |
| EN300-26486241 |
| 2-chloro-5-{[2-(nitroimino)imidazolidin-1-yl]methyl}pyridine |
| Z2859045865 |
| imidacloprid technical grade |
| 1-(6-chloro-3-pyridyl methyl)-n-nitroimidazolidin-3-ylideneamine |
| 2-imidazolidinimine, 1-((6-chloro-3-pyridinyl) methyl)-n-nitro- |
| 1-((6-chloropyridin-3-yl)methyl)-n-nitroimidazolidin-2-imine |
| 1-(6-chloro-3-pyridylmethyl)-n-nitroimidazolidin-3-ylideneamine |
| 1h-imidazol-2-amine, 1-((6-chloro-3-pyridinyl)methyl)-4,5-dihydro-n-nitro |
| 1-(6-chloro-3-pyridylmethyl)-n-nitroimidazolidine-2-ylideneamine |
| 1-(6-chloro-3-pyridin-3-ylmethyl)-n-nitroimidazolidin-2-ylidenamine |
| 1-(6-chloro-3-pyridinylmethyl)-n-nitroimidazolidin-2-ylideneamine |
| epa pesticide chemical code: 129099 |
| advantus |
| 105827-78-9 |
| smr000718777 |
| MLS001304087 |
| FT-0656073 |
| bdbm50212288 |
| n-[1-[(6-chloropyridin-3-yl)methyl]-4,5-dihydroimidazol-2-yl]nitramide |
| A801327 |
| n-[1-[(6-chloranylpyridin-3-yl)methyl]-4,5-dihydroimidazol-2-yl]nitramide |
| n-[1-[(6-chloro-3-pyridinyl)methyl]-4,5-dihydroimidazol-2-yl]nitramide |
| HMS2231F05 |
| AKOS015994761 |
| FT-0631157 |
| AKOS015895351 |
| HMS3373H06 |
| imidacloprid [green book] |
| imidacloprid [mi] |
| 1-((6-chloro-3-pyridinyl)methyl)-4,5-dihydro-n-nitro-1h-imidazol-2-amine |
| imidacloprid [hsdb] |
| AB00876233-04 |
| 1-((6-chloro-3-pyridinyl)methyl)-4,5-dihydro-n-nitro-imidazol-2-amine |
| J-007111 |
| n-(1-((6-chloropyridin-3-yl)methyl)-4,5-dihydro-1h-imidazol-2-yl)nitramide |
| 1-((6-chloro-3-pyridinyl)methyl)-n-nitro-4,5-dihydro-1h-imidazol-2-amine |
| E79264 |
| n-{1-[(6-chloro-3-pyridyl)methyl]-4,5-dihydroimidazol-2-yl}nitramide |
| 2-chloro-5-{[2-(nitroamino)-4,5-dihydro-1h-imidazol-1-yl]methyl}pyridine |
| 138261-41-3 |
| imidacloprid |
| 1-[(6-chloropyridin-3-yl)methyl]-n-nitroimidazolidin-2-imine |
| 1-(2-chloro-5-pyridylmethyl)-2-(nitroimino)imidazolidine |
| 1-(2-chloro-5-pyridyl-methyl)-2-(nitroimino)imidazolidine |
| 1-(2-chloro-5-pyridylmethyl)-2-nitroiminoimidazolidine |
| 1-(6-chloro-3-pyridyl)methyl-2-nitroiminoimidazolidine |
| 1-(6-chloronicotinyl)-2-nitroiminoimidazolidine |
| AKOS028109228 |
| 2-chloro-5-{[(2z)-2-(nitroimino)imidazolidin-1-yl]methyl}pyridine |
| (2e)-1-[(6-chloro-3-pyridinyl)methyl]-n-nitro-2-imidazolidinimine |
| (ez)-1-(6-chloro-3-pyridylmethyl)-n-nitroimidazolidin-2-ylideneamine |
| (e)-n-(1-((6-chloropyridin-3-yl)methyl)imidazolidin-2-ylidene)nitramide |
| BCP10193 |
Imidacloprid had genetic toxic effect on the loach erythrocytes. An average weight dove of 127g would obtain a dose equivalent to the LD50 of imidaclobrid by consuming 1. Imidaclubrid and triflumuron were very toxic to third instar larvae inhibiting adult emergence.
Experiments were carried out in the laboratory to assess the insecticidal effect on Myzus persicae Sulzer. It is known that adult mosquitoes are attracted to dark surfaces. Black cotton cloths impregnated with Metarhizium anisopliae alone or in combination with the insecticide imidacloprid were tested.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Experiments were carried out in the laboratory to assess the insecticidal effect on Myzus persicae Sulzer of different oils applied alone or combined with imidacloprid or pirimicarb." | ( Use of oils combined with low doses of insecticide for the control of Myzus persicae and PVY epidemics. Cabaleiro, C; Marnotes, S; Martín-López, B; Varela, I, 2006) | 0.33 |
| " It is known that adult mosquitoes are attracted to dark surfaces, and therefore, black cotton cloths impregnated with Metarhizium anisopliae alone or in combination with the insecticide imidacloprid (IMI) were tested under laboratory conditions." | ( Efficiency of fungus-impregnated black cloths combined with imidacloprid for the control of adult Aedes aegypti (Diptera: Culicidae). Carolino, AT; Paula, AR; Samuels, RI; Silva, CP, 2013) | 0.39 |
| "The objective of this study was to develop analytical method based on optimized dispersive liquid-liquid microextraction (DLLME) as a pretreatment procedure combined with reversed phase liquid chromatographic separation on C18 column and isocratic elution for simultaneous MS/MS determination of selected neonicotinoid insecticides in honey." | ( Multi-residue method for determination of selected neonicotinoid insecticides in honey using optimized dispersive liquid-liquid microextraction combined with liquid chromatography-tandem mass spectrometry. Banjac, V; Franko, M; Guzsvány, V; Jovanov, P; Lazić, S; Sakač, M; Šarić, B, 2013) | 0.39 |
| " In this work, our aim was to investigate side effects of imidacloprid treatment, either applied alone or in combination with organosilicone compounds, against Chrysoperla nipponensis, an important predator of aphids." | ( Effects of Imidacloprid Applied Alone or in Combination With Organosilicone Surfactants on Biological Traits and Predatory Feeding of Chrysoperla nipponensis (Neuroptera: Chrysopidae). Fan, J; Fan, R; Gao, Y; Liu, Z; Yang, J; Zhang, P, 2021) | 0.62 |
Imidacloprid sorption capacity on clay minerals and HA was reduced in the presence of the metabolite. Soil properties such as organic matter content, silt and clay proportions, pH, and cation exchange capacity were suggested to affect the bioavailability of imidaclobrid.
| Excerpt | Reference | Relevance |
|---|---|---|
| " To show the importance of physicochemical properties, the classic QSAR and CoMFA of neonicotinoids and prediction of bioavailability of pesticides in terms of membrane permeability in comparison with drugs are described." | ( Importance of physicochemical properties for the design of new pesticides. Akamatsu, M, 2011) | 0.37 |
| "The ATP-binding cassette transporter P-glycoprotein (P-gp) is known to limit both brain penetration and oral bioavailability of many chemotherapy drugs." | ( A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Ambudkar, SV; Brimacombe, KR; Chen, L; Gottesman, MM; Guha, R; Hall, MD; Klumpp-Thomas, C; Lee, OW; Lee, TD; Lusvarghi, S; Robey, RW; Shen, M; Tebase, BG, 2019) | 0.51 |
| " Soil properties such as organic matter content, silt and clay proportions, pH, and cation exchange capacity were suggested to affect the bioavailability of imidacloprid." | ( Feeding inhibition and mortality in Reticulitermes flavipes (Isoptera: Rhinotermitidae) after exposure to imidacloprid-treated soils. Bennett, GW; Nakatsu, CH; Ramakrishnan, R; Suiter, DR, 2000) | 0.31 |
| " The results showed that the sorption capacity of imidacloprid on clay minerals and HA was reduced in the presence of the metabolite, implying that imidacloprid-urea could occupy or block adsorption sites of imidacloprid on soil, potentially affecting the fate, transport, and bioavailability of imidacloprid in the environment." | ( Competitive sorption between imidacloprid and imidacloprid-urea on soil clay minerals and humic acids. Gan, J; Liu, W; Zheng, W, 2002) | 0.31 |
| " A laboratory study was undertaken to investigate its systemic properties and translaminar bioavailability in hop leaves." | ( Uptake, translocation and bioavailability of imidacloprid in several hop varieties. Nauen, R; Weichel, L, 2004) | 0.32 |
| " New formulations have been developed to optimize the bioavailability of neonicotinoids through improved rain fastness, better retention and spreading of the spray deposit on the leaf surface, combined with higher leaf penetration." | ( Applied aspects of neonicotinoid uses in crop protection. Elbert, A; Haas, M; Nauen, R; Springer, B; Thielert, W, 2008) | 0.35 |
| "Degradation and bioavailability of imidacloprid, fipronil, and bifenthrin applied at label rates ([AI], wt:wt in soil) in the loamy soil of Nebraska were determined over a 6-mo duration." | ( Concentration-dependent degradation of three termiticides in soil under laboratory conditions and their bioavailability to eastern subterranean termites (Isoptera: Rhinotermitidae). Kamble, ST; Saran, RK, 2008) | 0.35 |
| " Commercially, it is co-formulated with dimethyl sulfoxide, methylpyrrolidone, propylene carbonate and mineral oil, which can modify its bioavailability and toxicological profile for humans following occupational exposure." | ( Genotoxicity of imidacloprid in relation to metabolic activation and composition of the commercial product. Catania, S; Costa, C; De Pasquale, R; Heffron, JJ; Melchini, A; Silvari, V; Trovato, A, 2009) | 0.35 |
| " To show the importance of physicochemical properties, the classic QSAR and CoMFA of neonicotinoids and prediction of bioavailability of pesticides in terms of membrane permeability in comparison with drugs are described." | ( Importance of physicochemical properties for the design of new pesticides. Akamatsu, M, 2011) | 0.37 |
On dosed syrup, honey bees maintained much lower bodily levels of imidacloprid than bumblebees. Exposure groups had 12 to 313 times more imidcloprid in the brain relative to the control and breakdown products showed a dose-response relationship. Results of dietary exposure assessment showed that the RQ values were much lower than 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Numbers of live whiteflies were well correlated with the dosage of active ingredients." | ( Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton. Greenberg, SM; Liu, TX; Zhang, L; Zhang, Y, 2011) | 0.37 |
| " Dose-response and activities of detoxication enzymes of the fenvalerate-resistant strain (R-fenvalerate), the imidacloprid-resistant strain (R-imidacloprid), and a susceptible strain (S) were determined." | ( Resistance of aphis gossypii (Homoptera: Aphididae) to fenvalerate and imidacloprid and activities of detoxification enzymes on cotton and cucumber. Jiang, XY; Liu, TX; Wang, KY; Yi, MQ; Yu, CH, 2002) | 0.31 |
| " Unit-dose applicators and the dosing schedule used in these studies were designed to provide a minimum of 10mg imidacloprid and 1mg moxidectin/kg." | ( Imidacloprid/moxidectin topical solution for the prevention of heartworm disease and the treatment and control of flea and intestinal nematodes of cats. Arther, RG; Charles, S; Ciszewski, DK; Davis, WL; Settje, TS, 2005) | 0.33 |
| " All Sarcoptes-infested dogs were topically treated twice (days 0 and 28) with the dosage recommended by the respective manufacturer (27 dogs with imidacloprid/moxidectin, 26 with selamectin)." | ( Efficacy and safety of imidacloprid 10% plus moxidectin 2.5% spot-on in the treatment of sarcoptic mange and otoacariosis in dogs: results af a European field study. Dumont, P; Heine, J; Hellmann, K; Krieger, K, 2005) | 0.33 |
| " Dose-response data yield an EC(50) value for ACh of 19 microm." | ( Neonicotinoid insecticides display partial and super agonist actions on native insect nicotinic acetylcholine receptors. Brown, LA; Buckingham, SD; Ihara, M; Matsuda, K; Sattelle, DB, 2006) | 0.33 |
| " Using dose-response assays, the presence of resistant individuals was disclosed in both these strains; some individuals were unaffected at doses high enough to induce phytotoxic effects." | ( Report of resistance to the neonicotinoid insecticide imidacloprid in Trialeurodes vaporariorum (Hemiptera: Aleyrodidae). Bennison, J; Coussons, P; Denholm, I; Devine, G; Gorman, K; Punchard, N, 2007) | 0.34 |
| " To assess post-treatment persistent efficacy, flea infestations were repeated at regular post-treatment intervals, beginning on Day 5 through Day 89 in the dose selection study and Day 58 in the impact of food type and dosing study." | ( Preliminary studies on the effectiveness of the novel pulicide, spinosad, for the treatment and control of fleas on dogs. Cruthers, LR; Gissendanner, SJ; Meyer, J; Qiao, M; Slone, RL; Snyder, DE; Young, DR; Zimmermann, AG, 2007) | 0.34 |
| " Aloperine, which possesses a unique structure and showed a distinctive dose-response curve, was found to act as an antagonist." | ( Actions of quinolizidine alkaloids on Periplaneta americana nicotinic acetylcholine receptors. Alam, MS; Hirata, K; Liu, L; Matsuda, K; Ozoe, Y, 2008) | 0.35 |
| " Introduction of the insect-specific loops D, E and F, singly or together, into rat beta2 subunit resulted in a leftward shift of the imidacloprid dose-response curves for nAChRs Nlalpha1-beta2 chimeras, reflecting decreases in EC(50), compared to wildtype nAChRs Nlalpha1-beta2." | ( Amino acids within loops D, E and F of insect nicotinic acetylcholine receptor beta subunits influence neonicotinoid selectivity. Chen, F; Gu, J; Liu, S; Liu, Z; Song, F; Yao, X; Zhang, Y, 2008) | 0.35 |
| " Dose-response lines showed resistance in one of the most resistant field strains to be approximately 100-fold compared with the susceptible standard." | ( Neonicotinoid resistance in rice brown planthopper, Nilaparvata lugens. Brüggen, KU; Denholm, I; Gorman, K; Liu, Z; Nauen, R, 2008) | 0.35 |
| "Film coating enabled superior pesticide dosage as well as higher biological efficacy to be achieved." | ( An analysis of the persistence and potency of film-coated seed protectant as influenced by various storage parameters. Arunkumar, MB; Gopal, M; Jacob, SR; Sinha, SN; Srivastava, C, 2009) | 0.35 |
| " When these chimeras were co-expressed with insect Nlalpha1, it was found that the replacement of loops D, E and F of beta2(Mpbeta1) by that of Ppbeta1 resulted in a right-ward shift of the imidacloprid dose-response curves, reflecting increases in EC(50), compared to Nlalpha1/beta2(Mpbeta1)." | ( Specific loops D, E and F of nicotinic acetylcholine receptor beta1 subunit may confer imidacloprid selectivity between Myzus persicae and its predatory enemy Pardosa pseudoannulata. Cheng, J; Lin, K; Liu, Z; Song, F; Yao, X; You, Z, 2009) | 0.35 |
| " Dose-response bioassays were conducted to determine relative tolerances to the insecticides pirimicarb, dimethoate, and imidacloprid; these results have been reported previously." | ( Relationship of insecticide tolerance to esterase enzyme activity in Aphis pomi and Aphis spiraecola (Hemiptera: Aphididae). Foottit, RG; Lowery, DT; Smirle, MJ; Zurowski, CL, 2010) | 0.36 |
| " Recently, similar dose-response characteristics have been established for the toxicity of the neonicotinoid insecticides imidacloprid and thiacloprid to arthropods." | ( The significance of the Druckrey-Küpfmüller equation for risk assessment--the toxicity of neonicotinoid insecticides to arthropods is reinforced by exposure time. Tennekes, HA, 2010) | 0.36 |
| " Numbers of live whiteflies were well correlated with the dosage of active ingredients." | ( Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton. Greenberg, SM; Liu, TX; Zhang, L; Zhang, Y, 2011) | 0.37 |
| " In a meta-analysis of fourteen published studies of the effects of imidacloprid on honey bees under laboratory and semi-field conditions that comprised measurements on 7073 adult individuals and 36 colonies, fitted dose-response relationships estimate that trace dietary imidacloprid at field-realistic levels in nectar will have no lethal effects, but will reduce expected performance in honey bees by between 6 and 20%." | ( A meta-analysis of experiments testing the effects of a neonicotinoid insecticide (imidacloprid) on honey bees. Cresswell, JE, 2011) | 0.37 |
| " Complete dose-response bioassays were performed on three of the isolates that had triggered a second test and produced slopes, intercepts and LC(50) values similar to those for existing susceptible laboratory strains." | ( Large-scale monitoring of imidacloprid susceptibility in the cat flea, Ctenocephalides felis. Blagburn, BL; Bond, R; Coleman, G; Denholm, I; Dryden, MW; Jacobs, DE; Kopp, S; Mencke, N; Payne, P; Rust, MK; Schroeder, I; Vaughn, M; Weston, S, 2011) | 0.37 |
| " In the larvicide experiments, both sand fly species demonstrated a typical dose-response curve with the strongest lethal effect for the 250 ppm samples." | ( Imidacloprid as a potential agent for the systemic control of sand flies. Chenault, M; Miller, D; Poché, R; Rowton, ED; Wasserberg, G; Zollner, G, 2011) | 0.37 |
| "1 x dosage had sufficient adelgids to possibly sustain predators over extended periods." | ( Effects of fertilizer and low rates of imidacloprid on Adelges tsugae (Hemiptera: Adelgidae). Braman, SK; Byrne, FJ; Hanula, JL; Joseph, SV, 2011) | 0.37 |
| " Beetles exposed repeatedly to 50 ppm imidacloprid died in < 2-3 wk, whether dosed orally each day, or through contact exposure." | ( The effect of exposure to imidacloprid on Asian longhorned beetle (Coleoptera: Cerambycidae) survival and reproduction. Gardescu, S; Hajek, AE; Ugine, TA, 2011) | 0.37 |
| "The optimal dosage level of the combination for hedgehogs was determined by assigning 20 hedgehogs into three treatment groups (0." | ( Efficacy of a combination of 10% imidacloprid and 1% moxidectin against Caparinia tripilis in African pygmy hedgehog (Atelerix albiventris). Ahn, KS; Kim, KR; Oh, DS; Shin, SS, 2012) | 0.38 |
| " Dose-response regression lines from the mortality data established LC50 and LC99 values by both techniques." | ( Baseline susceptibility of Planococcus ficus (Hemiptera: Pseudococcidae) from California to select insecticides. Castle, SJ; Gispert, C; Prabhaker, N, 2012) | 0.38 |
| " Xenopus oocytes voltage clamp experiments as hybrids with the chicken β2 nAChR (Ggβ2) subunit resulted in ACh-gated ion channels with distinct dose-response curves for Lcα1/Ggβ2 (effective concentration 50% [EC50 ] = 80 nM; nH = 1." | ( Structure-activity relationships of acetylcholine derivatives with Lucilia cuprina nicotinic acetylcholine receptor α1 and α2 subunits in chicken β2 subunit hybrid receptors in comparison with chicken nicotinic acetylcholine receptor α4/β2. Berger, M; Dederer, H; Ilg, T; Meyer, T; Werr, M, 2013) | 0.39 |
| " In the laboratory, the authors therefore fed adult worker bees on dosed syrup (125 μg L(-1) of imidacloprid, or 98 μg kg(-1)) either continuously or as a pulsed exposure and measured their behaviour (feeding and locomotory activity) and whole-body residues." | ( Clearance of ingested neonicotinoid pesticide (imidacloprid) in honey bees (Apis mellifera) and bumblebees (Bombus terrestris). Cresswell, JE; Florance, H; Robert, FX; Smirnoff, N, 2014) | 0.4 |
| "On dosed syrup, honey bees maintained much lower bodily levels of imidacloprid than bumblebees (<0." | ( Clearance of ingested neonicotinoid pesticide (imidacloprid) in honey bees (Apis mellifera) and bumblebees (Bombus terrestris). Cresswell, JE; Florance, H; Robert, FX; Smirnoff, N, 2014) | 0.4 |
| " The dosage for all treatments was the licensed dose of 10–25 mg imidacloprid/2." | ( The efficacy of a topically applied imidacloprid 10 % / moxidectin 2.5 % formulation (Advocate®, Advantage® Multi, Bayer) against Immature and Adult Spirocerca lupi worms in experimentally infected dogs. Austin, CM; Crafford, D; Kok, DJ; Schaper, R, 2013) | 0.39 |
| " Estimates of response parameters for each mixture component applied to each species were compared with dose-response data for each mixture in statistical tests of the hypothesis of independent joint action." | ( Comparative toxicities and synergism of apple orchard pesticides to Apis mellifera (L.) and Osmia cornifrons (Radoszkowski). Ashcraft, SA; Biddinger, DJ; Frazier, J; Joshi, NK; Mullin, C; Rajotte, EG; Robertson, JL; Vaughn, M, 2013) | 0.39 |
| " To address questions related to the nature of the dose-response and potential consequences on biological fitness, we examined transgenerational hormesis in the green peach aphid, Myzus persicae, when exposed to sublethal concentrations of the insecticide imidacloprid." | ( Transgenerational shifts in reproduction hormesis in green peach aphid exposed to low concentrations of imidacloprid. Ayyanath, MM; Cutler, GC; Scott-Dupree, CD; Sibley, PK, 2013) | 0.39 |
| " During the initial 'on dose' period we observed a dose-dependent repression of brood production in colonies, with productivity decreasing as dosage increased up to 98 µg kg(-1) dietary imidacloprid." | ( Repression and recuperation of brood production in Bombus terrestris bumble bees exposed to a pulse of the neonicotinoid pesticide imidacloprid. Cresswell, JE; Laycock, I, 2013) | 0.39 |
| " Results showed that bumble bee workers survived fewer days when presented with syrup dosed at 98 μg thiamethoxamkg(-1), while production of brood (eggs and larvae) and consumption of syrup and pollen in microcolonies were significantly reduced by thiamethoxam only at the two highest concentrations (39, 98 μgkg(-1))." | ( Effects of the neonicotinoid pesticide thiamethoxam at field-realistic levels on microcolonies of Bombus terrestris worker bumble bees. Cotterell, KC; Cresswell, JE; Laycock, I; O'Shea-Wheller, TA, 2014) | 0.4 |
| " Treatments were 25, 50, and 100% of the highest labeled dosage rates for both stem and soil injection." | ( Impacts of trunk and soil injections of low rates of imidacloprid on hemlock woolly adelgid (Hemiptera: Adelgidae) and eastern hemlock (Pinales: Pinaceae) health. Eisenback, BM; Kok, LT; Lagalante, AF; Salom, SM, 2014) | 0.4 |
| " The parametric indices selected give a quantitative dose-response relationship of both insecticides and indicate that ACE is more toxic than IMI due to their difference in molecular structures." | ( Influence of short-time imidacloprid and acetamiprid application on soil microbial metabolic activity and enzymatic activity. Chen, H; Choi, MM; Wang, F; Yao, J; Yi, Z, 2014) | 0.4 |
| " Although the adult bioassays permitted a more precise dosage applied, the larval bioassays allowed for testing isolates without the need to maintain on synthetic or natural hosts." | ( Susceptibility of cat fleas (Siphonaptera: Pulicidae) to fipronil and imidacloprid using adult and larval bioassays. Blagburn, B; Coleman, G; Davis, W; Denholm, I; Foit, S; Hostetler, J; Kopp, S; Mencke, N; Rees, R; Rust, MK; Tetzner, K; Vetter, R; Williamson, MS, 2014) | 0.4 |
| " Results of bioassays on the model insect showed that by using the nanoform of imidacloprid, essential dosage of pesticide and environmental risk decreased significantly and indicated good performance for this formulation." | ( Preparation, characterization and efficiency of nanoencapsulated imidacloprid under laboratory conditions. Adeli, M; Ghadamyari, M; Memarizadeh, N; Talebi, K, 2014) | 0.4 |
| " indica CGMCC 6648 rapidly degrades IMI and forms olefin IMI, which may enhance its potential for biodegradation of IMI and increase its insecticidal activity, which can decrease the IMI dosage required." | ( Co-metabolic transformation of the neonicotinoid insecticide imidacloprid by the new soil isolate Pseudoxanthomonas indica CGMCC 6648. Dai, YJ; Liu, ZH; Ma, Y; Mao, SY; Sun, SL; Wang, Y; Yuan, S; Zhai, S, 2014) | 0.4 |
| " This blinded, randomized three-phase clinical trial compared its efficacy employing different dosing regimens with that of ivermectin." | ( Canine generalized demodicosis treated with varying doses of a 2.5% moxidectin+10% imidacloprid spot-on and oral ivermectin: parasiticidal effects and long-term treatment outcomes. Ball, G; Fields, PJ; Halliwell, RE; Louw, J; Louw, ML; Paterson, TE; Pinckney, R, 2014) | 0.4 |
| " 15-days subchronic test, in which lizards were orally dosed on alternate days at 0, 10, 50, 100 mg/kg bw, showed a dose-dependent changes of testicular architecture and an increase of apoptotic processes." | ( Imidacloprid induces morphological and molecular damages on testis of lizard (Podarcis sicula). Cardone, A, 2015) | 0.42 |
| " The obtained data showed a negative effect by imidacloprid applied at the FR dosage for substrate-induced respiration (SIR), the number of total bacteria, dehydrogenase (DHA), both phosphatases (PHOS-H and PHOS-OH), and urease (URE) at the beginning of the experiment." | ( Biochemical and microbial soil functioning after application of the insecticide imidacloprid. Cycoń, M; Piotrowska-Seget, Z, 2015) | 0.42 |
| " However, the calculation of the richness (S) and the Shannon-Wiener index (H) values for soil treated with the field rate (FR) dosage of imidacloprid (1 mg/kg soil) showed no changes in measured indices for the AOA and AOB community members." | ( Community structure of ammonia-oxidizing archaea and ammonia-oxidizing bacteria in soil treated with the insecticide imidacloprid. Cycoń, M; Piotrowska-Seget, Z, 2015) | 0.42 |
| " Results of dietary exposure assessment showed that the RQ values were much lower than 1, indicating that the risk of imidacloprid and chlorfenapyr applied in chieh-qua was negligible to human health under recommended dosage and good agricultural practices." | ( Residue behavior and risk assessment of mixed formulation of imidacloprid and chlorfenapyr in chieh-qua under field conditions. Chen, JJ; Deng, YC; Huang, JX; Liu, CY; Lu, DH; Wang, FH, 2015) | 0.42 |
| " When dogs receive consecutive doses of Advantage Multi for Dogs as prescribed, heartworm infections will be prevented throughout the monthly dosing interval after administration of several monthly doses." | ( Protection of dogs against canine heartworm infection 28 days after four monthly treatments with Advantage Multi® for Dogs. Basel, C; Bowman, DD; Grazette, AR; Hostetler, JA; Wang, Y, 2016) | 0.43 |
| " Group 4 was dosed once on Day 0 with Bravecto™." | ( Comparative efficacy of oral administrated afoxolaner (NexGard™) and fluralaner (Bravecto™) with topically applied permethrin/imidacloprid (Advantix(®)) against transmission of Ehrlichia canis by infected Rhipicephalus sanguineus ticks to dogs. Crafford, D; Erasmus, H; Fourie, JJ; Jongejan, F; Schunack, B, 2016) | 0.43 |
| "A total of 122 aphid samples/clones from central and northern Greece were examined in dose-response bioassays with imidacloprid." | ( Evolution of imidacloprid resistance in Myzus persicae in Greece and susceptibility data for spirotetramat. Kati, AN; Margaritopoulos, JT; Sahinoglou, AJ; Skouras, PJ; Voudouris, CC; Williamson, MS, 2017) | 0.46 |
| " Some impacts were more pronounced in specific dosing periods, implying that there may be critical windows of development when embryos are more susceptible to neonicotinoid exposure." | ( The effects of neonicotinoid exposure on embryonic development and organ mass in northern bobwhite quail (Colinus virginianus). Crossley, D; Gobeli, A; Johnson, J; Reyna, K, 2017) | 0.46 |
| " Evaluations are based on a dose-response or concentration-response curve, where mortality increases as the dose or concentration of an insecticide is increased." | ( A Method for Evaluating Insecticide Efficacy against Bed Bug, Cimex lectularius, Eggs and First Instars. Campbell, BE; Miller, DM, 2017) | 0.46 |
| " The treatment regimen of monthly IMD + MOX topically (per labeled dosage and administration) for 10 months and 10 mg/kg doxycycline BID orally for 30 days was initiated 30 days post-surgical transplant." | ( Assessment of parasitological findings in heartworm-infected beagles treated with Advantage Multi® for dogs (10% imidacloprid + 2.5% moxidectin) and doxycycline. Dzimianski, MT; Hostetler, JA; Moorhead, AR; Ohmes, CM; Savadelis, MD; Settje, TL; Zolynas, R, 2017) | 0.46 |
| " During spring migration, sparrows were captured, held and dosed by gavage daily for 3 days with either the vehicle control, low (10% LD50) or high (25% LD50) doses of imidacloprid or chlorpyrifos and tested in migratory orientation trials pre-exposure, post-exposure and during recovery." | ( Imidacloprid and chlorpyrifos insecticides impair migratory ability in a seed-eating songbird. Eng, ML; Morrissey, CA; Stutchbury, BJM, 2017) | 0.46 |
| " As previously found in honey bees, the dose-response relationship for imidacloprid exhibited a biphasic hormesis with low-dose stimulation and high-dose inhibition, for which we propose a mechanism." | ( The effect of dietary neonicotinoid pesticides on non-flight thermogenesis in worker bumble bees (Bombus terrestris). Clarke, RM; Cresswell, JE; Hempel de Ibarra, N; Oldfield, SE; Potts, R; Wood, LK, 2018) | 0.48 |
| " In this context, gene duplication performs an adaptive function as a result of its effects on gene dosage and not as a source of functional novelty [3, 6-8]." | ( Neofunctionalization of Duplicated P450 Genes Drives the Evolution of Insecticide Resistance in the Brown Planthopper. Bass, C; Davies, TGE; Garrood, WT; Gutbrod, O; Kohler, M; Lueke, B; Matthiesen, S; Nauen, R; Randall, E; Singh, KS; Zimmer, CT, 2018) | 0.48 |
| "5, 55, 550, and 5,500 ppm) administered in artificial diet to approximate the dosage required to reduce feeding activity and prevent salivation/ingestion activity." | ( Evaluating the Effect of Imidacloprid Administered in Artificial Diet on Feeding Behavior of Diaphorina citri (Hemiptera: Liviidae) Using Electropenetrography. Ebert, TA; Langdon, KW; Rogers, ME, 2019) | 0.51 |
| " We tracked the migratory movements of imidacloprid-exposed songbirds at a landscape scale using a combination of experimental dosing and automated radio telemetry." | ( A neonicotinoid insecticide reduces fueling and delays migration in songbirds. Eng, ML; Morrissey, CA; Stutchbury, BJM, 2019) | 0.51 |
| " Twenty-two dogs with HWI whose owners declined melarsomine were treated with M/I at the preventive dosage twice monthly for 90 days then monthly thereafter and doxycycline (median [interquartile range; IQR] dosage 12." | ( Non-Arsenical heartworm adulticidal therapy using topical moxidectin-imidacloprid and doxycycline: A prospective case series. Ames, MK; Atkins, CE; Evans, C; VanVranken, P, 2020) | 0.56 |
| "5 times more imidacloprid into shoot tissues when compared to the root pathway at the same dosage rate." | ( Uptake and translocation of imidacloprid via seed pathway and root pathway during early seedling growth of corn. Hao, F; Tang, X; Taylor, AG; Yan, X; Yang, D; Yuan, H, 2020) | 0.56 |
| " Considering that in the field it is common to find extrapolated concentrations, our work suggested that water may allow avoidance of high dosed food and minimize mortality." | ( Is the Water Supply a Key Factor in Stingless Bees' Intoxication? Dorigo, AS; Malaspina, O; Nocelli, RCF; Rosa-Fontana, AS; Soares-Lima, HM, 2020) | 0.56 |
| " Following the dosing of Japanese quail (Coturnix japonica) with imidacloprid-treated wheat seeds, plasma, liver, and fecal matter samples were analyzed by ELISA and compared to previous analyses that employed liquid chromatography-tandem mass spectrometry (LC-MS/MS)." | ( Evaluation of ELISA for the analysis of imidacloprid in biological matrices: Cross-reactivities, matrix interferences, and comparison to LC-MS/MS. Gross, MS; Hladik, ML; Woodward, EE, 2022) | 0.72 |
| " Exposure groups had 12 to 313 times more imidacloprid in the brain relative to the control and breakdown products showed a dose-response relationship." | ( Detection of imidacloprid and metabolites in Northern Leopard frog (Rana pipiens) brains. Campbell, KS; Golovko, MY; Golovko, SA; Heinzel, LM; Keller, PG; Kerby, JL; Seeger, DR, 2022) | 0.72 |
| " The degradation efficiencies of IMI were in the range of 82-97% with the PS dosage of 10 mM, when the initial concentrations of IMI were 5-50 mg/kg in the soil." | ( Efficient degradation of imidacloprid in soil by thermally activated persulfate process: Performance, kinetics, and mechanisms. Guo, X; Huang, X; Jia, C; Li, B; Wu, J; Zhao, E; Zou, Z, 2022) | 0.72 |
| " In addition, the adverse effects did not show a dose-response relationship with increased imidacloprid concentrations, where no significant difference was observed among the treatment groups." | ( The neonicotinoid insecticide imidacloprid has unexpected effects on the growth and development of soil amoebae. He, Z; Huang, W; Liu, Z; Shu, L; Wang, Z; Zeng, J, 2023) | 0.91 |
| " Also, TML oral dosing markedly reduced the release of inflammatory elements, including nitric oxide and myeloperoxidase, resulting from IMID exposure." | ( Thymol abates the detrimental impacts of imidacloprid on rat brains by lessening oxidative damage and apoptotic and inflammatory reactions. Abd-Allah, NA; Abd-Elhakim, YM; Ahmed, GA; Metwally, MMM; Mohamed, RMSM; Saber, TM, 2023) | 0.91 |
| Role | Description |
|---|---|
| nicotinic acetylcholine receptor agonist | An agonist that selectively binds to and activates a nicotinic acetylcholine receptor. |
| neonicotinoid insectide | A class of neuro-active insecticides that act at the nicotinic acetylcholine receptor. |
| xenobiotic | A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. |
| environmental contaminant | Any minor or unwanted substance introduced into the environment that can have undesired effects. |
| genotoxin | A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells. |
| nicotinic acetylcholine receptor agonist | An agonist that selectively binds to and activates a nicotinic acetylcholine receptor. |
| neonicotinoid insectide | A class of neuro-active insecticides that act at the nicotinic acetylcholine receptor. |
| xenobiotic | A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. |
| environmental contaminant | Any minor or unwanted substance introduced into the environment that can have undesired effects. |
| genotoxin | A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells. |
| nicotinic acetylcholine receptor agonist | An agonist that selectively binds to and activates a nicotinic acetylcholine receptor. |
| neonicotinoid insectide | A class of neuro-active insecticides that act at the nicotinic acetylcholine receptor. |
| xenobiotic | A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. |
| environmental contaminant | Any minor or unwanted substance introduced into the environment that can have undesired effects. |
| genotoxin | A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| imidacloprid | An imidazolidine that is N-nitroimidazolidin-2-imine bearing a (6-chloro-3-pyridinyl)methyl substituent at position 1. |
| imidazolidines | |
| monochloropyridine | A chloropyridine in which only one chlorine is attached to the pyridine ring. |
| imidacloprid | An imidazolidine that is N-nitroimidazolidin-2-imine bearing a (6-chloro-3-pyridinyl)methyl substituent at position 1. |
| imidacloprid | An imidazolidine that is N-nitroimidazolidin-2-imine bearing a (6-chloro-3-pyridinyl)methyl substituent at position 1. |
| imidazolidines | |
| monochloropyridine | A chloropyridine in which only one chlorine is attached to the pyridine ring. |
| imidacloprid | An imidazolidine that is N-nitroimidazolidin-2-imine bearing a (6-chloro-3-pyridinyl)methyl substituent at position 1. |
| imidacloprid | An imidazolidine that is N-nitroimidazolidin-2-imine bearing a (6-chloro-3-pyridinyl)methyl substituent at position 1. |
| imidazolidines | |
| monochloropyridine | A chloropyridine in which only one chlorine is attached to the pyridine ring. |
| imidacloprid | An imidazolidine that is N-nitroimidazolidin-2-imine bearing a (6-chloro-3-pyridinyl)methyl substituent at position 1. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 13.3332 | 0.0060 | 38.0041 | 19,952.5996 | AID1159521 |
| GALC protein | Homo sapiens (human) | Potency | 0.7079 | 28.1838 | 28.1838 | 28.1838 | AID1159614 |
| TDP1 protein | Homo sapiens (human) | Potency | 7.2038 | 0.0008 | 11.3822 | 44.6684 | AID686978; AID686979 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 23.7101 | 0.0007 | 14.5928 | 83.7951 | AID1259369 |
| AR protein | Homo sapiens (human) | Potency | 1.9484 | 0.0002 | 21.2231 | 8,912.5098 | AID743036 |
| progesterone receptor | Homo sapiens (human) | Potency | 33.4915 | 0.0004 | 17.9460 | 75.1148 | AID1346784 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 6.0070 | 0.0002 | 14.3764 | 60.0339 | AID720691 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 13.3993 | 0.0002 | 29.3054 | 16,493.5996 | AID743069; AID743080 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 10.0000 | 0.0237 | 23.2282 | 63.5986 | AID588543 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 79.4328 | 0.0040 | 23.8416 | 100.0000 | AID485290 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 2.8184 | 0.0447 | 17.8581 | 100.0000 | AID485294 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 44.6684 | 0.6310 | 35.7641 | 100.0000 | AID504339 |
| TDP1 protein | Homo sapiens (human) | Potency | 9.4765 | 0.0008 | 11.3822 | 44.6684 | AID686978; AID686979 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 50.1187 | 0.5318 | 15.4358 | 37.6858 | AID504845 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 89.1251 | 0.3548 | 28.0659 | 89.1251 | AID504847 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 26.6795 | 0.1683 | 16.4040 | 67.0158 | AID720504 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 1.1220 | 0.1585 | 5.2879 | 12.5893 | AID540303 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 1.1220 | 0.1585 | 5.2879 | 12.5893 | AID540303 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 1.1220 | 0.1585 | 5.2879 | 12.5893 | AID540303 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Nicotinic acetylcholine receptor Dalpha7 | Drosophila melanogaster (fruit fly) | Ki | 0.0021 | 0.0021 | 0.0021 | 0.0021 | AID147717 |
| Nicotinic acetylcholine receptor alpha 5 subunit | Musca domestica (house fly) | Ki | 0.0046 | 0.0046 | 0.0046 | 0.0046 | AID1091970 |
| Nicotinic acetylcholine receptor | Drosophila melanogaster (fruit fly) | Ki | 0.0021 | 0.0021 | 0.0021 | 0.0021 | AID147717 |
| Nicotinic acetylcholine receptor alpha4, isoform D | Drosophila melanogaster (fruit fly) | Ki | 0.0021 | 0.0021 | 0.0021 | 0.0021 | AID147717 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 (µMol) | 1,000.0000 | 0.0340 | 3.9871 | 10.0000 | AID1082239 |
| Neuronal acetylcholine receptor subunit alpha-4 | Mus musculus (house mouse) | IC50 (µMol) | 2.6000 | 0.0000 | 0.5799 | 2.6000 | AID1101291 |
| Acetylcholine receptor subunit alpha | Homo sapiens (human) | IC50 (µMol) | 300.0000 | 0.0079 | 4.7136 | 7.9000 | AID1101295 |
| Acetylcholine receptor subunit beta-like 1 | Drosophila melanogaster (fruit fly) | Ki | 0.0021 | 0.0021 | 0.0021 | 0.0021 | AID147717 |
| Acetylcholine receptor subunit alpha-like 1 | Drosophila melanogaster (fruit fly) | Ki | 0.0021 | 0.0021 | 0.0021 | 0.0021 | AID147717 |
| Neuronal acetylcholine receptor subunit alpha-4 | Gallus gallus (chicken) | IC50 (µMol) | 2.6000 | 0.8600 | 1.7300 | 2.6000 | AID344087 |
| Neuronal acetylcholine receptor subunit alpha-4 | Gallus gallus (chicken) | Ki | 0.9700 | 0.0000 | 0.3157 | 0.9700 | AID1092036 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 0.0500 | 0.0000 | 0.1234 | 5.5000 | AID145520 |
| Muscarinic acetylcholine receptor DM1 | Drosophila melanogaster (fruit fly) | Ki | 100.0000 | 0.0005 | 1.4249 | 5.2000 | AID1090601; AID1090602 |
| Acetylcholine receptor subunit alpha-like 2 | Drosophila melanogaster (fruit fly) | Ki | 0.0021 | 0.0021 | 0.0021 | 0.0021 | AID147717 |
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | Ki | 0.7200 | 0.0000 | 0.1117 | 3.5400 | AID146171 |
| Acetylcholine receptor subunit beta-like 2 | Drosophila melanogaster (fruit fly) | IC50 (µMol) | 0.0035 | 0.0023 | 0.8531 | 4.0000 | AID1101022; AID1101298 |
| Acetylcholine receptor subunit beta-like 2 | Drosophila melanogaster (fruit fly) | Ki | 0.0025 | 0.0012 | 0.5719 | 2.7000 | AID1092037; AID147717 |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | IC50 (µMol) | 14.0000 | 0.0018 | 1.3132 | 6.5000 | AID1101292 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | IC50 (µMol) | 270.0000 | 0.0020 | 4.1527 | 9.9000 | AID1101293 |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | Ki | 0.7200 | 0.0000 | 0.1157 | 3.5400 | AID146171 |
| Acetylcholine-binding protein | Lymnaea stagnalis (great pond snail) | Ki | 0.9700 | 0.0001 | 1.8811 | 28.0000 | AID1092034 |
| Nicotinic acetyl choline receptor alpha-subunit | Myzus persicae (green peach aphid) | Ki | 0.0019 | 0.0019 | 0.0019 | 0.0019 | AID147718 |
| Nicotinic acetylcholine receptor, alpha7-2 subunit | Myzus persicae (green peach aphid) | Ki | 0.0019 | 0.0019 | 0.0019 | 0.0019 | AID147718 |
| Nicotinic acetylcholine receptor, alpha7-1 subunit | Myzus persicae (green peach aphid) | Ki | 0.0019 | 0.0019 | 0.0019 | 0.0019 | AID147718 |
| Nicotinic acetylcholine receptor, alpha5 subunit | Myzus persicae (green peach aphid) | Ki | 0.0019 | 0.0019 | 0.0019 | 0.0019 | AID147718 |
| Liver carboxylesterase B-1 | Rattus norvegicus (Norway rat) | IC50 (µMol) | 14.0000 | 0.0140 | 0.0295 | 0.0450 | AID1101292 |
| Nicotinic acetylcholine receptor alpha5, isoform B | Drosophila melanogaster (fruit fly) | Ki | 0.0021 | 0.0021 | 0.0021 | 0.0021 | AID147717 |
| Nicotinic acetylcholine receptor alpha6, isoform E | Drosophila melanogaster (fruit fly) | Ki | 0.0021 | 0.0021 | 0.0021 | 0.0021 | AID147717 |
| Soluble acetylcholine receptor | Aplysia californica (California sea hare) | Ki | 0.0190 | 0.0010 | 1.2276 | 6.3096 | AID1092035 |
| Forkhead box protein A2-A | Xenopus laevis (African clawed frog) | Ki | 0.0019 | 0.0019 | 0.0019 | 0.0019 | AID147718 |
| Putative nicotinic acetylcholine receptor subunit | Myzus persicae (green peach aphid) | Ki | 0.0019 | 0.0019 | 0.0019 | 0.0019 | AID147718 |
| Nicotinic acetylcholine receptor alpha 4 subunit | Myzus persicae (green peach aphid) | Ki | 0.0019 | 0.0019 | 0.0019 | 0.0019 | AID147718 |
| Nicotinic acetylcholine receptor alpha 3 subunit | Myzus persicae (green peach aphid) | Ki | 0.0019 | 0.0019 | 0.0019 | 0.0019 | AID147718 |
| Nicotinic acetylcholine receptor beta 3 | Drosophila melanogaster (fruit fly) | Ki | 0.0021 | 0.0021 | 0.0021 | 0.0021 | AID147717 |
| Nicotinic acetylcholine receptor alpha3, isoform B | Drosophila melanogaster (fruit fly) | Ki | 0.0021 | 0.0021 | 0.0021 | 0.0021 | AID147717 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1347424 | RapidFire Mass Spectrometry qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46 | Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
| AID1347407 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Pharmaceutical Collection | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7 | High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID1347092 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1 | Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347090 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347097 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347093 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347103 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347108 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347104 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347425 | Rhodamine-PBP qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46 | Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
| AID1347091 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347095 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347100 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4 | A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347098 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347106 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347096 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
| AID1347089 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347105 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347102 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347107 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347099 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347094 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347101 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1081822 | Insecticidal activity against Myzus persicae (green peach aphid) infested UV irradiated leaves of pepper plant exposed to compound at 124 ppm assessed as insect control efficacy post 0 day UV exposure relative to untreated control | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1104194 | Resistance factor, ratio of LC50 for female B-biotype Bemisia tabaci NJ-Imi F1' (sweet potato whitefly) progeny to LC50 for adult female B-type Bemisia tabaci NJ | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1111986 | Insecticidal activity against cotton aphid Aphis gossypii F6 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1104221 | Inhibition of Ceutorhynchus obstrictus preimaginal development in Brassica napus L. Ryder pods of plant developed from compound treated seeds assessed as decrease in number of second-instar larvae at 800 g/L FS by microscopic analysis | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1112902 | Displacement of [3H]IMD from nAChR in Myzus persicae 4106A (green peach aphid) membrane after 70 min | 2013 | Pest management science, May, Volume: 69, Issue:5 | Investigating the mode of action of sulfoxaflor: a fourth-generation neonicotinoid. |
| AID1104694 | Contact toxicity against Rhopalosiphum padi infested wheat plant applied as spray measured after 24 hr | 2010 | Pest management science, Jul, Volume: 66, Issue:7 | Systemic action of novel neonicotinoid insecticide IPP-10 and its effect on the feeding behaviour of Rhopalosiphum padi on wheat. |
| AID1082842 | Insecticidal activity against Myzus persicae (green peach aphid) at 25 degC | 2012 | Journal of agricultural and food chemistry, May-23, Volume: 60, Issue:20 | N'-Nitro-2-hydrocarbylidenehydrazinecarboximidamides: design, synthesis, crystal structure, insecticidal activity, and structure-activity relationships. |
| AID1090572 | Insecticidal activity against Aphis craccivora (cowpea aphid) assessed as mortality at 500 mg/l measured after 24 hr | 2007 | Journal of agricultural and food chemistry, Mar-21, Volume: 55, Issue:6 | Synthesis, insecticidal activity, and QSAR of novel nitromethylene neonicotinoids with tetrahydropyridine fixed cis configuration and exo-ring ether modification. |
| AID1104202 | Insecticidal activity against adult female imidacloprid-resistant Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioa | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1082710 | Insecticidal activity against adult Aphis craccivora (cowpea aphid) assessed as larvicidal activity at 500 mg/l after 24 hr | 2012 | Journal of agricultural and food chemistry, Jan-11, Volume: 60, Issue:1 | Design, synthesis, and particular biological behaviors of chain-opening nitromethylene neonicotinoids with cis configuration. |
| AID323217 | Insecticidal activity against Myzus persicae Sulzer in raddish plant by systemic plant assay | 2008 | Bioorganic & medicinal chemistry, Mar-15, Volume: 16, Issue:6 | Synthesis of insecticidal fluorinated anthranilic diamides. |
| AID1104745 | Insecticidal activity against Bemisia tabaci biotype-B B1 (sweet potato whitefly) after 48 hr by leaf-dip bioassay | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1111084 | Insecticidal activity against Amphimallon majalis (European chafer) assessed as mortality after 30 days | 2010 | Pest management science, Jan, Volume: 66, Issue:1 | Variation in the laboratory susceptibility of turf-infesting white grubs (Coleoptera: Scarabaeidae) to biological, biorational and chemical control products. |
| AID1104185 | Insecticidal activity against adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay in presence of 100 | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1091958 | Hydrophobicity, log P of the compound in octanol-water by shaking-flask method | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Importance of physicochemical properties for the design of new pesticides. |
| AID1091959 | Toxic effect in Periplaneta americana (American cockroach) assessed as paralyzed insects after 24 hr of abdomen compound injection by insecticidal assay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Importance of physicochemical properties for the design of new pesticides. |
| AID1112865 | Insecticidal activity against second generation Blissus occiduus in buffalograss under field condition assessed as reduction in number at 9.6 kg/ha measured 3 days after treatment | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Effect of distribution and concentration of topically applied neonicotinoid insecticides in buffalograss, Buchloe dactyloides, leaf tissues on the differential mortality of Blissus occiduus under field conditions. |
| AID1112903 | Displacement of [3H]-methyl-SFX from nAChR in Myzus persicae 4106A (green peach aphid) membrane after 70 min | 2013 | Pest management science, May, Volume: 69, Issue:5 | Investigating the mode of action of sulfoxaflor: a fourth-generation neonicotinoid. |
| AID1104715 | Selectivity ratio of LC50 for pymetrozine-selected Bemisia tabaci B2 (sweet potato whitefly) to LC50 for Bemisia tabaci B2 | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1098937 | Insecticidal activity against Nephotettix cincticeps (green rice leafhopper) in compound treated germinated rice seedlings assessed as mortality measured after 5 days | 1993 | Bioscience, biotechnology, and biochemistry, Jan, Volume: 57, Issue:1 | Structural Modification of the 6-Chloropyridyl Moiety in the Imidacloprid, Skeleton: Introduction of a Five-membered Heteroaromatic Ring and the Resulting Insecticidal Activity. |
| AID1104197 | Insecticidal activity against female F1' progeny generated from reciprocal cross between male B-biotype Bemisia tabaci NJ-Imi (sweet potato whitefly) with female B-biotype Bemisia tabaci NJ in cotton leaf discs assessed as mortality treated for 10 secs pr | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1104862 | Insecticidal activity against Diaphorina citri assessed as mortality after 48 hr | 2011 | Pest management science, Jan, Volume: 67, Issue:1 | Effect of Candidatus Liberibacter asiaticus infection on susceptibility of Asian citrus psyllid, Diaphorina citri, to selected insecticides. |
| AID1111082 | Insecticidal activity against Anomala orientalis assessed as mortality after 20 days | 2010 | Pest management science, Jan, Volume: 66, Issue:1 | Variation in the laboratory susceptibility of turf-infesting white grubs (Coleoptera: Scarabaeidae) to biological, biorational and chemical control products. |
| AID1081196 | Insecticidal activity against Aphis craccivora (cowpea aphid) in tender shoots of soybean assessed as mortality at 500 mg/L measured after 1 days (Rvb = 4.3%) | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Design, multicomponent synthesis, and bioactivities of novel neonicotinoid analogues with 1,4-dihydropyridine scaffold. |
| AID1112898 | Resistance index, ratio of LC50 for neonicotinoid-resistant Myzus persicae FRC-P (green peach aphid) to LC50 for Myzus persicae 4106A | 2013 | Pest management science, May, Volume: 69, Issue:5 | Investigating the mode of action of sulfoxaflor: a fourth-generation neonicotinoid. |
| AID1080506 | Insecticidal activity against Mythimna separata (Oriental armyworm) second-instar larvae infested on compound pre-treated corn leaves assessed as insect mortality at 500 mg/L measured 48 hr post compound treatment by leaf-dip method | 2009 | Journal of agricultural and food chemistry, Feb-11, Volume: 57, Issue:3 | Design, synthesis, and insecticidal activities of novel analogues of neonicotinoids: replacement of nitromethylene with nitroconjugated system. |
| AID344089 | Ratio of IC50 for Drosophila nAChR to chick alpha4beta2 nAChR | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14 | Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche. |
| AID1082244 | Phytotoxicity against Glycine max (soybean) seedlings assessed as lesions in unfoliolate leaves at 100 ppm after 9 days | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition. |
| AID1111977 | Insecticidal activity against cotton aphid Aphis gossypii F39 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1112856 | Insecticidal activity against second generation Blissus occiduus in buffalograss under field condition assessed as reduction in number at 9.6 kg/ha measured 55 days after treatment | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Effect of distribution and concentration of topically applied neonicotinoid insecticides in buffalograss, Buchloe dactyloides, leaf tissues on the differential mortality of Blissus occiduus under field conditions. |
| AID146171 | Potency to displace [3H]nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 immuno-isolated from M10 cells | 2002 | Journal of medicinal chemistry, Jun-20, Volume: 45, Issue:13 | Structural features of azidopyridinyl neonicotinoid probes conferring high affinity and selectivity for mammalian alpha4beta2 and Drosophila nicotinic receptors. |
| AID1091953 | Insecticidal activity against Nephotettix cincticeps (green rice leafhopper) in rice plant assessed as mortality at 100 mg/L insects released after 7 days of compound treatment measured after 72 hr of insect release (Rvb = 0%) | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery of imidacloprid and further developments from strategic molecular designs. |
| AID1081282 | Insecticidal activity against apterous adult stage of Aphis fabae (black bean aphids) in soybean tender shoots assessed as mortality at 200 mg/l treated for 5 secs measured after 2 hr by modified FAO dip test | 2010 | Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3 | Synthesis and insecticidal evaluation of N-tert-butyl-N'-thio[1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine]-N,N'-diacylhydrazines. |
| AID1104203 | Insecticidal activity against adult female imidacloprid-resistant Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G15) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioa | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1091949 | Insecticidal activity against Nephotettix cincticeps (green rice leafhopper) in rice plant assessed as mortality at 100 mg/L insects released after 3 days of compound treatment measured after 48 hr of insect release | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery of imidacloprid and further developments from strategic molecular designs. |
| AID1081789 | Insecticidal activity against imidacloprid-resistant Nilaparvata lugens (brown planthopper) assessed as mortality | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | cis-Configuration: a new tactic/rationale for neonicotinoid molecular design. |
| AID1112848 | Drug level in Urochloa mutica (buffalo grass) measured per gram of fresh weight at 89.7 kg/ha measured 14 days after treatment | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Effect of distribution and concentration of topically applied neonicotinoid insecticides in buffalograss, Buchloe dactyloides, leaf tissues on the differential mortality of Blissus occiduus under field conditions. |
| AID1104690 | Toxicity against Rhopalosiphum padi infested wheat plant assessed as mortality at 1000 mg/l applied to upper plant for 1 min followed by basipetal transportation for 24 hr measured 48 hr after removal of upper plant parts relative to control | 2010 | Pest management science, Jul, Volume: 66, Issue:7 | Systemic action of novel neonicotinoid insecticide IPP-10 and its effect on the feeding behaviour of Rhopalosiphum padi on wheat. |
| AID1112207 | Insecticidal activity against Paralobesia viteana infested grapevine assessed as reduction in clusters infested with moth by early-season irrigation injection method (Rvb = 34.3 +/- 4.4 %) | 2012 | Pest management science, Apr, Volume: 68, Issue:4 | Soil application of neonicotinoid insecticides for control of insect pests in wine grape vineyards. |
| AID1111958 | Resistance ratio, LC50 for Aphis gossypii F45 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1104883 | Insecticidal activity against adult Bemisia tabaci (sweet potato whitefly) infested cotton leaves assessed as increase in mortality at 0.375 mg ai/seed measured 10 to 40 days post germination under laboratory conditions relative to untreated control | 2011 | Pest management science, Feb, Volume: 67, Issue:2 | Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton. |
| AID1110827 | Insecticidal activity against drug-susceptible Bemisia tabaci SUD-S (sweet potato whitefly) in cotton plant leaf assessed as mortality after 48 hr | 2009 | Pest management science, Feb, Volume: 65, Issue:2 | An analogue of piperonyl butoxide facilitates the characterisation of metabolic resistance. |
| AID288185 | Permeability coefficient through artificial membrane in presence of stirred water layer | 2007 | Bioorganic & medicinal chemistry, Jun-01, Volume: 15, Issue:11 | QSAR study on permeability of hydrophobic compounds with artificial membranes. |
| AID1081197 | Insecticidal activity against Aphis craccivora (cowpea aphid) in tender shoots of soybean assessed as mortality measured after 1 days | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Design, multicomponent synthesis, and bioactivities of novel neonicotinoid analogues with 1,4-dihydropyridine scaffold. |
| AID1090557 | Hydrophobicity, log P of the compound in octanol-water by shaking-flask method | 2007 | Journal of agricultural and food chemistry, Feb-07, Volume: 55, Issue:3 | Insecticidal and neuroblocking potencies of variants of the imidazolidine moiety of imidacloprid-related neonicotinoids and the relationship to partition coefficient and charge density on the pharmacophore. |
| AID1082841 | Insecticidal activity against Myzus persicae (green peach aphid) measured in field test | 2012 | Journal of agricultural and food chemistry, May-23, Volume: 60, Issue:20 | N'-Nitro-2-hydrocarbylidenehydrazinecarboximidamides: design, synthesis, crystal structure, insecticidal activity, and structure-activity relationships. |
| AID1111956 | Insecticidal activity against Aphis gossypii SS (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1081791 | Insecticidal activity against Aphis craccivora (cowpea aphid) assessed as mortality | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | cis-Configuration: a new tactic/rationale for neonicotinoid molecular design. |
| AID1104861 | Selectivity ratio of LC50 for Diaphorina citri to LC50 for Diaphorina citri infected with Candidatus Liberibacter asiaticus | 2011 | Pest management science, Jan, Volume: 67, Issue:1 | Effect of Candidatus Liberibacter asiaticus infection on susceptibility of Asian citrus psyllid, Diaphorina citri, to selected insecticides. |
| AID1632164 | Acaricidal activity against Tetranychus cinnabarinus assessed as mortality at 200 ug/ml pre-incubated with mite-infested Sieva bean plants for 3 secs and measured 48 hrs post dose | 2016 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18 | Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety. |
| AID1104208 | Inhibition of Ceutorhynchus obstrictus development in canola pods of plant developed from compound treated seeds assessed as decrease in number of exit holes formed by larvae at 0.45 kg AI per 45.36 kg seeds relative to untreated control | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1632166 | Acaricidal activity against Tetranychus cinnabarinus assessed as mortality at 50 ug/ml pre-incubated with mite-infested Sieva bean plants for 3 secs and measured 48 hrs post dose | 2016 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18 | Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety. |
| AID1082840 | Insecticidal activity against Brevicoryne brassicae (cabbage aphids) measured in field test | 2012 | Journal of agricultural and food chemistry, May-23, Volume: 60, Issue:20 | N'-Nitro-2-hydrocarbylidenehydrazinecarboximidamides: design, synthesis, crystal structure, insecticidal activity, and structure-activity relationships. |
| AID1101293 | Inhibition of [3H]alpha-BGT binding to alpha7 nicotinic acetylcholine receptor in Homo sapiens (human) SH-SY5Y cells | 2000 | Journal of agricultural and food chemistry, Dec, Volume: 48, Issue:12 | Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors. |
| AID1102410 | Displacement of [3HIMI from nicotinic acetylcholine receptor in Musca domestica (house fly) head membranes incubated for 60 min by liquid scintillation counting method | 2003 | Bioscience, biotechnology, and biochemistry, May, Volume: 67, Issue:5 | Asymmetric chloronicotinyl insecticide, 1-[1-(6-chloro-3-pyridyl)ethyl]-2-nitroiminoimidazolidine: preparation, resolution and biological activities toward insects and their nerve preparations. |
| AID1632161 | Insecticidal activity against Aphis craccivora assessed as mortality at 200 ug/ml pre-incubated with horsebean shoot with aphids for 2 secs and measured 48 hrs post dose by foliar application method | 2016 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18 | Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety. |
| AID1110826 | Insecticidal activity against drug-resistant Bemisia tabaci GUAMIX (sweet potato whitefly) in cotton plant leaf assessed as mortality after 48 hr | 2009 | Pest management science, Feb, Volume: 65, Issue:2 | An analogue of piperonyl butoxide facilitates the characterisation of metabolic resistance. |
| AID1101021 | Displacement of [3H]IMI from nicotinic acetylcholine receptor in Musca domestica (house fly) head membrane after 90 min by filter binding assay | 2000 | Journal of neurochemistry, Sep, Volume: 75, Issue:3 | Insect nicotinic acetylcholine receptor: conserved neonicotinoid specificity of [(3)H]imidacloprid binding site. |
| AID1081740 | Binding affinity to Nephotettix cincticeps (green rice leafhopper) nicotinic acetylcholine receptor | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Molecular design of dinotefuran with unique insecticidal properties. |
| AID1091947 | Photolysis of the compound assessed as half life at 30 degC by 250 W sun lamp | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery of imidacloprid and further developments from strategic molecular designs. |
| AID1104193 | Insecticidal activity against adult female Bemisia tabaci B-biotype NJ (sweet potato whitefly) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay in presence of 100 mg/L cyto | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1103847 | Insecticidal activity against Nilaparvata lugens (brown planthopper) offspring obtained after 23 selected generations in rice stem assessed as mortality treated for 30 secs prior to nymph infestation measured at 96 hr post-drug treatment by rice-stem dipp | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Inheritance mode and realized heritability of resistance to imidacloprid in the brown planthopper, Nilaparvata lugens (Stål) (Homoptera: Delphacidae). |
| AID1081067 | Insecticidal activity against Aphis craccivora (cowpea aphid) in compound treated horsebean plant leaves assessed as mortality at 500 mg/L measured after 24 hr by leaf-dip method | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Synthesis, crystal structure, and insecticidal activities of highly congested hexahydroimidazo[1,2-a]pyridine derivatives: effect of conformation on activities. |
| AID1112917 | Insecticidal activity against orange/yellow Diaphorina citri in citrus leaf assessed as mortality after 48 hr by leaf-dip petridish bioassay method | 2013 | Pest management science, Apr, Volume: 69, Issue:4 | Abdominal color of the Asian citrus psyllid, Diaphorina citri, is associated with susceptibility to various insecticides. |
| AID1103849 | Insecticidal activity against Nilaparvata lugens (brown planthopper) F1' progeny generated from reciprocal cross between male imidacloprid-susceptible strain and female imidaclporid-resistant strain in rice stem assessed as mortality treated for 30 secs p | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Inheritance mode and realized heritability of resistance to imidacloprid in the brown planthopper, Nilaparvata lugens (Stål) (Homoptera: Delphacidae). |
| AID1111080 | Insecticidal activity against Maladera castanea assessed as mortality after 10 days | 2010 | Pest management science, Jan, Volume: 66, Issue:1 | Variation in the laboratory susceptibility of turf-infesting white grubs (Coleoptera: Scarabaeidae) to biological, biorational and chemical control products. |
| AID1091952 | Insecticidal activity against Nephotettix cincticeps (green rice leafhopper) in rice plant assessed as mortality at 100 mg/L insects released after 7 days of compound treatment measured after 48 hr of insect release | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery of imidacloprid and further developments from strategic molecular designs. |
| AID1081834 | Insecticidal activity against DAS insecticide-resistant Bemisia tabaci B-biotype R-PBI (sweet potato whitefly) by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1081289 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 200 mg/l after 4 days | 2010 | Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3 | Synthesis and insecticidal evaluation of N-tert-butyl-N'-thio[1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine]-N,N'-diacylhydrazines. |
| AID1101291 | Inhibition of [3H]nicotine binding to alpha4 nicotinic acetylcholine receptor in Mus musculus (mouse) M10 cells co-expressing beta2 nicotinic acetylcholine receptor subunits | 2000 | Journal of agricultural and food chemistry, Dec, Volume: 48, Issue:12 | Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors. |
| AID1082239 | Inhibition of Agaricus bisporus (mushroom) tyrosinase | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition. |
| AID1112859 | Insecticidal activity against second generation Blissus occiduus in buffalograss under field condition assessed as reduction in number at 9.6 kg/ha measured 28 days after treatment | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Effect of distribution and concentration of topically applied neonicotinoid insecticides in buffalograss, Buchloe dactyloides, leaf tissues on the differential mortality of Blissus occiduus under field conditions. |
| AID1103884 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as average number of eggs laid (fecundity) at 0.1600 g AI/L treated using worst-case laboratory exposure procedure measured after 48 hr (Rvb | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1111954 | Resistance ratio, LC50 for Aphis gossypii RF45 (cotton aphid) to LC50 for Aphis gossypii SS | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1112838 | Insecticidal activity against first generation Blissus occiduus in buffalograss under field condition assessed as reduction in number at 9.6 kg/ha measured 8 days after treatment | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Effect of distribution and concentration of topically applied neonicotinoid insecticides in buffalograss, Buchloe dactyloides, leaf tissues on the differential mortality of Blissus occiduus under field conditions. |
| AID371215 | Insecticidal activity against imidacloprid-resistant Nilaparvata lugens | 2008 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 18, Issue:24 | cis-Nitromethylene neonicotinoids as new nicotinic family: synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-alpha]pyridine. |
| AID1104188 | Insecticidal activity against adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G15) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay in presence of 100 | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1111949 | Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as inhibition of honeydew excretion at LC20 concentration measured after 72 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1104182 | Synergistic ratio of LC50 for adult female Bemisia tabaci B-biotype NJ (sweet potato whitefly) to LC50 for adult female Bemisia tabaci B-biotype NJ in presence of 100 mg/L esterase inhibitor, DEF | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1081287 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 50 mg/l after 4 days | 2010 | Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3 | Synthesis and insecticidal evaluation of N-tert-butyl-N'-thio[1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine]-N,N'-diacylhydrazines. |
| AID1081832 | Insecticidal activity against rothamsted-resistant Bemisia tabaci R-4991BT1 (sweet potato whitefly) by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1091986 | Insecticidal activity against Aphis medicaginis assessed as insect mortality at 10 mg/L measured after 72 hr post compound treatment | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Chiral 1,5-disubstituted 1,3,5-hexahydrotriazine-2-N-nitroimine analogues as novel potent neonicotinoids: Synthesis, insecticidal evaluation and molecular docking studies. |
| AID1111181 | Cross resistant, ratio of LC50 for B-biotype thiamethoxam-resistant Bemisia tabaci (sweet potato whitefly) to LC50 for B-biotype thiamethoxam-sensitive Bemisia tabaci (sweet potato whitefly) | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Cross-resistance study and biochemical mechanisms of thiamethoxam resistance in B-biotype Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1111081 | Insecticidal activity against Anomala orientalis assessed as mortality after 30 days | 2010 | Pest management science, Jan, Volume: 66, Issue:1 | Variation in the laboratory susceptibility of turf-infesting white grubs (Coleoptera: Scarabaeidae) to biological, biorational and chemical control products. |
| AID1104731 | Resistance ratio of LC50 for Bemisia tabaci biotype-Q Q2 (sweet potato whitefly) to LC50 for Bemisia tabaci LABS | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID371213 | Insecticidal activity against Aphis craccivora | 2008 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 18, Issue:24 | cis-Nitromethylene neonicotinoids as new nicotinic family: synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-alpha]pyridine. |
| AID1081837 | Insecticidal activity against Latrodectus hesperus DAS lab strain by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1081148 | Toxicity ratio of imidacloprid LC50 to compound LC50 for macropterous adult stage of imidaclopride-sensitive Nilaparvata lugens (brown planthopper) after 48 hr by microtopical application technique | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Divalent and oxabridged neonicotinoids constructed by dialdehydes and nitromethylene analogues of imidacloprid: design, synthesis, crystal structure, and insecticidal activities. |
| AID1111979 | Insecticidal activity against cotton aphid Aphis gossypii F33 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1104196 | Resistance factor, ratio of LC50 for female Bemisia tabaci B-biotype NJ-Imi F1 (sweet potato whitefly) progeny to LC50 for adult female B-type Bemisia tabaci NJ | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1111973 | Insecticidal activity against cotton aphid Aphis gossypii F3 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1111957 | Resistance ratio, LC50 for Aphis gossypii F42 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1102412 | Insecticidal activity against female Musca domestica (house fly) administered through injection into dorsal side of thorax pre-treated with 0.2% w/v NIA and 0.2% w/v PB before compound injection measured 1 hr post dose | 2003 | Bioscience, biotechnology, and biochemistry, May, Volume: 67, Issue:5 | Asymmetric chloronicotinyl insecticide, 1-[1-(6-chloro-3-pyridyl)ethyl]-2-nitroiminoimidazolidine: preparation, resolution and biological activities toward insects and their nerve preparations. |
| AID1111967 | Resistance ratio, LC50 for Aphis gossypii F15 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1101294 | Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta1 nicotinic acetylcholine receptor at >300 uM | 2000 | Journal of agricultural and food chemistry, Dec, Volume: 48, Issue:12 | Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors. |
| AID1632162 | Insecticidal activity against Aphis craccivora assessed as mortality at 100 ug/ml pre-incubated with horsebean shoot with aphids for 2 secs and measured 48 hrs post dose by foliar application method | 2016 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18 | Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety. |
| AID1111971 | Resistance ratio, LC50 for Aphis gossypii F3 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1112015 | Termiticidal activity against Reticulitermes flavipes after 3 days by forced exposure test | 2012 | Pest management science, Jan, Volume: 68, Issue:1 | Bifenthrin longevity at the termiticidal application rate. |
| AID1081840 | Insecticidal activity against Myzus persicae S-USIL (green peach aphid) by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1101292 | Inhibition of [3H]nicotine binding to alpha3 nicotinic acetylcholine receptor in Homo sapiens (human) SH-SY5Y cells co-expressing beta2beta4alpha5 Nicotinic acetylcholine receptor subunits | 2000 | Journal of agricultural and food chemistry, Dec, Volume: 48, Issue:12 | Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors. |
| AID1104181 | Synergistic ratio of LC50 for adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G15) to LC50 for adult female Bemisia tabaci B-biotype NJ in presence of 100 mg/L cytochrome P450 monoxygenase inhibitor, PBO | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1104870 | Drug uptake in Gossypium hirsutum (cotton) leaf at 0.375 mg ai/seed measured 10 days post germination under green house conditions | 2011 | Pest management science, Feb, Volume: 67, Issue:2 | Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton. |
| AID1111963 | Resistance ratio, LC50 for Aphis gossypii F27 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID147717 | Binding affinity for nAChR with [3H]imidacloprid in Drosophila | 2000 | Journal of medicinal chemistry, Dec-28, Volume: 43, Issue:26 | 5-Azidoimidacloprid and an acyclic analogue as candidate photoaffinity probes for mammalian and insect nicotinic acetylcholine receptors. |
| AID344082 | Displacement of [3H]IMI from nAChR in Drosophila brain | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14 | Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche. |
| AID1081829 | Insecticidal activity against rothamsted-resistant Bemisia tabaci Q-biotype R-CHLORAKA (sweet potato whitefly) by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1111980 | Insecticidal activity against cotton aphid Aphis gossypii F27 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1081819 | Drug metabolism in Drosophila melanogaster D.mel-2 cells deficient in CYP6G1 assessed as drug recovery measured 24 hr post dose by HPLC method | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1082230 | Insecticidal activity against Nilaparvata lugens (brown planthopper) assessed as mortality at 500 mg/l after 72 hr | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Synthesis, insecticidal activity, and molecular docking studies of nitenpyram analogues with a flexible ester arm anchored on tetrahydropyrimidine ring. |
| AID1111078 | Insecticidal activity against Maladera castanea assessed as mortality after 20 days | 2010 | Pest management science, Jan, Volume: 66, Issue:1 | Variation in the laboratory susceptibility of turf-infesting white grubs (Coleoptera: Scarabaeidae) to biological, biorational and chemical control products. |
| AID323215 | Insecticidal activity against Aphis gossypii glover in cotton/melon plant by systemic plant assay | 2008 | Bioorganic & medicinal chemistry, Mar-15, Volume: 16, Issue:6 | Synthesis of insecticidal fluorinated anthranilic diamides. |
| AID1112918 | Insecticidal activity against gray/brown Diaphorina citri in citrus leaf assessed as mortality after 48 hr by leaf-dip petridish bioassay method | 2013 | Pest management science, Apr, Volume: 69, Issue:4 | Abdominal color of the Asian citrus psyllid, Diaphorina citri, is associated with susceptibility to various insecticides. |
| AID1112853 | Drug level in Urochloa mutica (buffalo grass) measured per gram of fresh weight at 89.7 kg/ha measured 7 days after treatment | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Effect of distribution and concentration of topically applied neonicotinoid insecticides in buffalograss, Buchloe dactyloides, leaf tissues on the differential mortality of Blissus occiduus under field conditions. |
| AID1082424 | Insecticidal activity against Aphis craccivora (cowpea aphid) assessed as mortality at 500 mg/L after 24 hr by leaf-dip method | 2011 | Journal of agricultural and food chemistry, Oct-12, Volume: 59, Issue:19 | Design, synthesis, crystal structure analysis, and insecticidal evaluation of phenylazoneonicotinoids. |
| AID1081154 | Insecticidal activity against second instar larval stage of Mythimna separata (Oriental armyworm) in compound pretreated corn leaves assessed as mortality at 25 +/-1degC after 48 hr | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Divalent and oxabridged neonicotinoids constructed by dialdehydes and nitromethylene analogues of imidacloprid: design, synthesis, crystal structure, and insecticidal activities. |
| AID1082232 | Inhibition of xanthine oxidase at IC50 concentration | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition. |
| AID1112900 | Insecticidal activity against neonicotinoid-resistant Myzus persicae FRC-P (green peach aphid) fed on compound treated chinese cabbage discs after 72 hr | 2013 | Pest management science, May, Volume: 69, Issue:5 | Investigating the mode of action of sulfoxaflor: a fourth-generation neonicotinoid. |
| AID1111978 | Insecticidal activity against cotton aphid Aphis gossypii F30 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1103867 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as repellency at 0.1600 g AI/L treated using worst-case laboratory exposure procedure measured after 48 hr (Rvb = 13.6%) | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1103890 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as average number of eggs laid (fecundity) at 0.1600 g AI/L treated using worst-case laboratory exposure procedure measured after 24 hr (Rvb | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID352725 | Insecticidal activity against Musca domestica Takatsuki assessed as mortality injected into thorax measured after 24 hrs | 2009 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 19, Issue:11 | Crown-capped imidacloprid: a novel design and insecticidal activity. |
| AID977599 | Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6 | Structure-based identification of OATP1B1/3 inhibitors. |
| AID1104866 | Insecticidal activity against adult Bemisia tabaci (sweet potato whitefly) infested cotton leaves assessed as increase in mortality at 0.375 mg ai/seed measured 2 weeks post sowing to 9 weeks under field conditions relative to untreated control | 2011 | Pest management science, Feb, Volume: 67, Issue:2 | Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton. |
| AID1103861 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as repellency at 0.1600 g AI/L treated using worst-case laboratory exposure procedure measured after 72 hr (Rvb = 16.1%) | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1081529 | Insecticidal activity against Aphis craccivora (cowpea aphid) infested tender soybean shoots exposed to compound solution assessed as insect mortality measured 24 hr post compound treatment (Rvb = 4.1%) | 2010 | Journal of agricultural and food chemistry, May-26, Volume: 58, Issue:10 | Designing Tetrahydroimidazo[1,2-a]pyridine derivatives via catalyst-free Aza-Diels-Alder reaction (ADAR) and their insecticidal evaluation. |
| AID1111985 | Insecticidal activity against cotton aphid Aphis gossypii F12 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1112802 | Insecticidal activity against Frankliniella occidentalis R1 (western flower thrips) in compound treated sweet pepper leaf assessed as mortality at 150 mg/l at 25 +/- 2 degC by leaf dip method | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Thiamethoxam acts as a target-site synergist of spinosad in resistant strains of Frankliniella occidentalis. |
| AID1110822 | Resistant factor, ratio of LC50 for drug-susceptible Bemisia tabaci SUD-S (sweet potato whitefly) to LC50 for drug-resistant Bemisia tabaci GUAMIX (sweet potato whitefly) in presence of EN 16/5-1 | 2009 | Pest management science, Feb, Volume: 65, Issue:2 | An analogue of piperonyl butoxide facilitates the characterisation of metabolic resistance. |
| AID1092036 | Binding affinity to recombinant Gallus gallus (chicken) alpha4beta2 nicotinic acetylcholine receptor assessed as [3H]NIC binding by radioligand binding assay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Unique neonicotinoid binding conformations conferring selective receptor interactions. |
| AID1111085 | Insecticidal activity against Amphimallon majalis (European chafer) assessed as mortality after 20 days | 2010 | Pest management science, Jan, Volume: 66, Issue:1 | Variation in the laboratory susceptibility of turf-infesting white grubs (Coleoptera: Scarabaeidae) to biological, biorational and chemical control products. |
| AID1082240 | Phytotoxicity against Vitis vinifera seedlings assessed as lesions at 50 to 100 ppm after 9 days | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition. |
| AID1081741 | Binding affinity to Laodelphax striatella (small brown planthopper) nicotinic acetylcholine receptor | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Molecular design of dinotefuran with unique insecticidal properties. |
| AID371212 | Insecticidal activity against Aphis craccivora assessed as mortality at 500 mg/L | 2008 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 18, Issue:24 | cis-Nitromethylene neonicotinoids as new nicotinic family: synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-alpha]pyridine. |
| AID344086 | Displacement of [3H]IMI from peach-potato aphid alpha2/rat beta2 nAChR hybrid recombinant receptor | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14 | Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche. |
| AID1104186 | Insecticidal activity against adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay in presence of 100 | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1080503 | Insecticidal activity against Laodelphax striatella (small brown planthopper) grown on booting stage rice plant stems assessed as insect mortality measured 48 hr post compound treatment by leaf-dip method | 2009 | Journal of agricultural and food chemistry, Feb-11, Volume: 57, Issue:3 | Design, synthesis, and insecticidal activities of novel analogues of neonicotinoids: replacement of nitromethylene with nitroconjugated system. |
| AID1104747 | Insecticidal activity against Bemisia tabaci LABS (sweet potato whitefly) after 48 hr by leaf-dip bioassay | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1091504 | Insecticidal activity against Aphis medicaginis in soybean tender shoots assessed as mortality at 0.2 mg/ml treated for 5 secs measured after 48 hr | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22 | Synthesis and biological activities of novel pyrazole oxime derivatives containing a 2-chloro-5-thiazolyl moiety. |
| AID1092035 | Binding affinity to salt water mollusc Aplysia californica AChBP Y55W mutant assessed as [3H]acetamiprid binding by radioligand binding assay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Unique neonicotinoid binding conformations conferring selective receptor interactions. |
| AID1082321 | Biotype susceptibility ratio, ratio of LC50 for female adult Bemisia tabaci biotype Q (sweet potato whitefly) to LC50 for female adult Bemisia tabaci biotype B | 2011 | Journal of agricultural and food chemistry, Aug-10, Volume: 59, Issue:15 | Adulticidal activity of phthalides identified in Cnidium officinale rhizome to B- and Q-biotypes of Bemisia tabaci. |
| AID1103854 | Toxicity against Metaseiulus occidentalis in hop fields assessed as mortality | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1104192 | Insecticidal activity against adult female Bemisia tabaci B-biotype NJ (sweet potato whitefly) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay in presence of 100 mg/L GSH | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1104206 | Inhibition of Ceutorhynchus obstrictus development in canola pods of plant developed from compound treated seeds assessed as decrease in number of exit holes formed by larvae at 0.28 kg AI per 45.36 kg seeds relative to untreated control | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1104220 | Inhibition of Ceutorhynchus obstrictus preimaginal development in Brassica napus L. Ryder pods of plant developed from compound treated seeds assessed as decrease in number of third-instar larvae at 800 g/L FS by microscopic analysis | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1112899 | Insecticidal activity against Myzus persicae 4106A (green peach aphid) fed on compound treated chinese cabbage discs after 72 hr | 2013 | Pest management science, May, Volume: 69, Issue:5 | Investigating the mode of action of sulfoxaflor: a fourth-generation neonicotinoid. |
| AID1112012 | Termiticidal activity against Reticulitermes flavipes assessed as mortality at 6.9 ug/g after 7 days by forced exposure test | 2012 | Pest management science, Jan, Volume: 68, Issue:1 | Bifenthrin longevity at the termiticidal application rate. |
| AID1104743 | Insecticidal activity against Bemisia tabaci biotype-B B2 (sweet potato whitefly) after 48 hr by leaf-dip bioassay | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1091944 | Insecticidal activity against Nephotettix cincticeps (green rice leafhopper) in rice plant assessed as mortality at 100 mg/L insects released after 14 days of compound treatment measured after 48 hr of insect release | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery of imidacloprid and further developments from strategic molecular designs. |
| AID1111964 | Resistance ratio, LC50 for Aphis gossypii F21 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1112800 | Insecticidal activity against Frankliniella occidentalis SPI5 (western flower thrips) in compound treated sweet pepper leaf assessed as mortality at 150 mg/l at 25 +/- 2 degC by leaf dip method | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Thiamethoxam acts as a target-site synergist of spinosad in resistant strains of Frankliniella occidentalis. |
| AID1080507 | Insecticidal activity against Aphis craccivora (cowpea aphid) infested horsebean plant leaves assessed as insect mortality measured 24 hr post compound treatment by leaf-dip method | 2009 | Journal of agricultural and food chemistry, Feb-11, Volume: 57, Issue:3 | Design, synthesis, and insecticidal activities of novel analogues of neonicotinoids: replacement of nitromethylene with nitroconjugated system. |
| AID1082227 | Insecticidal activity against Nilaparvata lugens (brown planthopper) assessed as mortality after 72 hr | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Synthesis, insecticidal activity, and molecular docking studies of nitenpyram analogues with a flexible ester arm anchored on tetrahydropyrimidine ring. |
| AID1104729 | Resistance ratio of LC50 for Bemisia tabaci biotype-B B1 (sweet potato whitefly) to LC50 for Bemisia tabaci LABS | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1081288 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 100 mg/l after 4 days | 2010 | Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3 | Synthesis and insecticidal evaluation of N-tert-butyl-N'-thio[1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine]-N,N'-diacylhydrazines. |
| AID288184 | Permeability coefficient through artificial membrane in presence of unstirred water layer by PAMPA | 2007 | Bioorganic & medicinal chemistry, Jun-01, Volume: 15, Issue:11 | QSAR study on permeability of hydrophobic compounds with artificial membranes. |
| AID1081839 | Insecticidal activity against drug resistant Myzus persicae R-4013A (green peach aphid) by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1110824 | Resistant factor, ratio of LC50 for drug-susceptible Bemisia tabaci SUD-S (sweet potato whitefly) to LC50 for drug-resistant Bemisia tabaci GUAMIX (sweet potato whitefly) | 2009 | Pest management science, Feb, Volume: 65, Issue:2 | An analogue of piperonyl butoxide facilitates the characterisation of metabolic resistance. |
| AID1081286 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 25 mg/l after 4 days | 2010 | Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3 | Synthesis and insecticidal evaluation of N-tert-butyl-N'-thio[1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine]-N,N'-diacylhydrazines. |
| AID1111976 | Insecticidal activity against cotton aphid Aphis gossypii F36 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1103873 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as repellency at 0.1600 g AI/L treated using worst-case laboratory exposure procedure measured after 24 hr (Rvb = 3.6%) | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1112222 | Insecticidal activity against Popillia japonica at 552 g/kg SC measured after 24 days by irrigation injection method | 2012 | Pest management science, Apr, Volume: 68, Issue:4 | Soil application of neonicotinoid insecticides for control of insect pests in wine grape vineyards. |
| AID977602 | Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6 | Structure-based identification of OATP1B1/3 inhibitors. |
| AID1082231 | Inhibition of Oryctolagus cuniculus (rabbit) AOX in liver cytosol at IC50 concentration | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition. |
| AID323216 | Insecticidal activity against Myzus persicae Sulzer in raddish plant by contact plant assay | 2008 | Bioorganic & medicinal chemistry, Mar-15, Volume: 16, Issue:6 | Synthesis of insecticidal fluorinated anthranilic diamides. |
| AID1080504 | Insecticidal activity against Nephotettix cincticeps (green rice leafhopper) grown on booting stage rice plant stems assessed as insect mortality measured 48 hr post compound treatment by leaf-dip method | 2009 | Journal of agricultural and food chemistry, Feb-11, Volume: 57, Issue:3 | Design, synthesis, and insecticidal activities of novel analogues of neonicotinoids: replacement of nitromethylene with nitroconjugated system. |
| AID344090 | Lipophilicity, log P of the compound | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14 | Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche. |
| AID1081831 | Insecticidal activity against rothamsted-resistant Bemisia tabaci Q-biotype R-4971BT9 (sweet potato whitefly) by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1081823 | Stability assessed as half life for photolysis in UV chamber at 1000 ppm by HPLC method | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1111952 | Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as mortality measured after 72 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1091502 | Insecticidal activity against Aphis medicaginis in soybean tender shoots assessed as mortality treated for 5 secs measured after 48 hr | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22 | Synthesis and biological activities of novel pyrazole oxime derivatives containing a 2-chloro-5-thiazolyl moiety. |
| AID1104864 | Insecticidal activity against nymph stage of Bemisia tabaci (sweet potato whitefly) infested cotton leaves assessed as increase in mortality at 0.375 mg ai/seed measured 2 weeks post sowing to 9 weeks under field conditions relative to untreated control | 2011 | Pest management science, Feb, Volume: 67, Issue:2 | Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton. |
| AID1091955 | Dissociation constant, pKa of the compound at pH 7.3 | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Importance of physicochemical properties for the design of new pesticides. |
| AID1104874 | Insecticidal activity against nymph stage of Bemisia tabaci (sweet potato whitefly) infested cotton leaves assessed as increase in mortality at 0.375 mg ai/seed measured 10 to 40 days post germination under green house conditions relative to untreated con | 2011 | Pest management science, Feb, Volume: 67, Issue:2 | Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton. |
| AID1103846 | Resistance ratio of LC50 for imidacloprid-resistance Nilaparvata lugens (brown planthopper) to LC50 for imidacloprid-susceptible brown planthopper | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Inheritance mode and realized heritability of resistance to imidacloprid in the brown planthopper, Nilaparvata lugens (Stål) (Homoptera: Delphacidae). |
| AID1632160 | Insecticidal activity against Plutella xylostella assessed as mortality at 50 ug/ml pre-incubated with cabbage leaves for 2 to 3 secs and measured 48 hrs post dose by leaf disc assay | 2016 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18 | Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety. |
| AID1104728 | Resistance ratio of LC50 for Bemisia tabaci biotype-B B2 (sweet potato whitefly) to LC50 for Bemisia tabaci LABS | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1081820 | Insecticidal activity against Myzus persicae (green peach aphid) infested UV irradiated leaves of pepper plant exposed to compound at 124 ppm assessed as insect control efficacy post 7 days UV exposure relative to untreated control | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1112208 | Insecticidal activity against Paralobesia viteana infested grapevine assessed as reduction in clusters infested with moth by mid-season irrigation injection method (Rvb = 11 +/- 1.9 %) | 2012 | Pest management science, Apr, Volume: 68, Issue:4 | Soil application of neonicotinoid insecticides for control of insect pests in wine grape vineyards. |
| AID1104748 | Insecticidal activity against Bemisia tabaci biotype-Q Q1 (sweet potato whitefly) after 48 hr by leaf-dip bioassay | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1080508 | Insecticidal activity against Aphis craccivora (cowpea aphid) infested horsebean plant leaves assessed as insect mortality at 500 mg/L measured 24 hr post compound treatment by leaf-dip method | 2009 | Journal of agricultural and food chemistry, Feb-11, Volume: 57, Issue:3 | Design, synthesis, and insecticidal activities of novel analogues of neonicotinoids: replacement of nitromethylene with nitroconjugated system. |
| AID1112937 | Insecticidal activity against Aphis craccivora (cowpea aphid) assessed as mortality | 2013 | Journal of agricultural and food chemistry, Jan-16, Volume: 61, Issue:2 | Pyrrole- and dihydropyrrole-fused neonicotinoids: design, synthesis, and insecticidal evaluation. |
| AID1082242 | Phytotoxicity against Gossypium hirsutum (cotton) seedlings assessed as lesions at 50 to 100 ppm after 9 days | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition. |
| AID1080614 | Displacement of [3H]IMI from nicotinic acetylcholine receptor in Drosophila melanogaster brain | 2009 | Journal of agricultural and food chemistry, Mar-25, Volume: 57, Issue:6 | Neonicotinoid substituents forming a water bridge at the nicotinic acetylcholine receptor. |
| AID1112919 | Insecticidal activity against blue/green Diaphorina citri in citrus leaf assessed as mortality after 48 hr by leaf-dip petridish bioassay method | 2013 | Pest management science, Apr, Volume: 69, Issue:4 | Abdominal color of the Asian citrus psyllid, Diaphorina citri, is associated with susceptibility to various insecticides. |
| AID1103844 | Resistance ratio of LC50 for Nilaparvata lugens (brown planthopper) F1' progeny to LC50 for imidacloprid-susceptible brown planthopper | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Inheritance mode and realized heritability of resistance to imidacloprid in the brown planthopper, Nilaparvata lugens (Stål) (Homoptera: Delphacidae). |
| AID1081836 | Insecticidal activity against Bemisia tabaci DAS (sweet potato whitefly) lab strain by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1081061 | Insecticidal activity against compound sensitive second-instar larvae Nilaparvata lugens (brown planthopper) in compound rice seedlings assessed as toxicity at 25 degC measured after 6 days relative to control | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Synthesis, crystal structure, and insecticidal activities of highly congested hexahydroimidazo[1,2-a]pyridine derivatives: effect of conformation on activities. |
| AID344083 | Insecticidal activity against houseflies | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14 | Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche. |
| AID1081826 | Resistance index, ratio of LC50 for drug resistant rothamsted-resistant Bemisia tabaci R-4991BT1 (sweet potato whitefly) to LC50 for DAS-susceptible Bemisia tabaci S-4971BT1 | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1082233 | Inhibition of Agaricus bisporus (mushroom) tyrosinase at IC50 concentration | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition. |
| AID1103895 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as corrected mortality at 0.1600/16 g AI/L treated using worst-case laboratory exposure procedure measured after 72 hr | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1081065 | Insecticidal activity against second-instar larvae Mythimna separata (Oriental armyworm) in compound treated corn leaves assessed as mortality at 500 mg/L measured after 48 hr | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Synthesis, crystal structure, and insecticidal activities of highly congested hexahydroimidazo[1,2-a]pyridine derivatives: effect of conformation on activities. |
| AID1104210 | Inhibition of Ceutorhynchus obstrictus development in canola pods of plant developed from compound treated seeds assessed as decrease in number of exit holes formed by larvae at 0.30 kg AI per 45.36 kg seeds relative to untreated control | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1104222 | Inhibition of Ceutorhynchus obstrictus preimaginal development in Brassica napus L. Ryder pods of plant developed from compound treated seeds assessed as effect on number of first-instar larvae at 800 g/L FS by microscopic analysis | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1104223 | Effect on Ceutorhynchus obstrictus oviposition in Brassica napus L. Ryder pods of plant developed from compound treated seeds assessed as number of eggs deposited at 800 g/L FS by microscopic analysis | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1103878 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as average number of eggs laid (fecundity) at 0.1600 g AI/L treated using worst-case laboratory exposure procedure measured after 72 hr (Rvb | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID288192 | Partition coefficient, log P of the compound | 2007 | Bioorganic & medicinal chemistry, Jun-01, Volume: 15, Issue:11 | QSAR study on permeability of hydrophobic compounds with artificial membranes. |
| AID1091987 | Insecticidal activity against Aphis medicaginis assessed as insect mortality at 100 mg/L measured after 72 hr post compound treatment | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Chiral 1,5-disubstituted 1,3,5-hexahydrotriazine-2-N-nitroimine analogues as novel potent neonicotinoids: Synthesis, insecticidal evaluation and molecular docking studies. |
| AID1104195 | Resistance factor, ratio of LC50 for adult male Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) to LC50 for adult female B-type Bemisia tabaci NJ | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID323212 | Insecticidal activity against Myzus persicae Sulzer in raddish plant | 2008 | Bioorganic & medicinal chemistry, Mar-15, Volume: 16, Issue:6 | Synthesis of insecticidal fluorinated anthranilic diamides. |
| AID1104216 | Inhibition of emergence of new-generation Ceutorhynchus obstrictus adults from soil harboring Brassica napus L. Ryder plant developed from compound treated seeds at 800 g/L FS measured for 5 weeks relative to lindane | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1091943 | Insecticidal activity against Nephotettix cincticeps (green rice leafhopper) in rice plant assessed as mortality at 100 mg/L insects released after 14 days of compound treatment measured after 72 hr of insect release (Rvb = 0%) | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery of imidacloprid and further developments from strategic molecular designs. |
| AID1090759 | Insecticidal activity against Aphis gossypii (cotton aphid) infested one week old Crookneck squash plants assessed as insect mortality measured after 3 days post compound application under green house conditions | 2007 | Journal of agricultural and food chemistry, Sep-05, Volume: 55, Issue:18 | Structure-activity relationship development of dihaloaryl triazole compounds as insecticides and acaricides. 1. Phenyl thiophen-2-yl triazoles. |
| AID1111974 | Insecticidal activity against cotton aphid Aphis gossypii F45 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1104213 | Inhibition of Ceutorhynchus obstrictus development in canola pods of plant developed from compound treated seeds assessed as decrease in number of exit holes formed by larvae at 0.38 kg AI per 45.36 kg seeds | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1102413 | Insecticidal activity against female Musca domestica (house fly) administered through injection into dorsal side of thorax measured 1 hr post dose | 2003 | Bioscience, biotechnology, and biochemistry, May, Volume: 67, Issue:5 | Asymmetric chloronicotinyl insecticide, 1-[1-(6-chloro-3-pyridyl)ethyl]-2-nitroiminoimidazolidine: preparation, resolution and biological activities toward insects and their nerve preparations. |
| AID1104214 | Inhibition of Ceutorhynchus obstrictus development in canola pods of plant developed from compound treated seeds assessed as decrease in number of exit holes formed by larvae at 0.30 kg AI per 45.36 kg seeds | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID145850 | Selectivity ratio of Ki of Nicotinic acetylcholine receptor of Drosophila to Nicotinic acetylcholine receptor alpha4-beta2 | 2002 | Journal of medicinal chemistry, Jun-20, Volume: 45, Issue:13 | Structural features of azidopyridinyl neonicotinoid probes conferring high affinity and selectivity for mammalian alpha4beta2 and Drosophila nicotinic receptors. |
| AID1104716 | Insecticidal activity against pymetrozine-selected Bemisia tabaci B2 (sweet potato whitefly) after 48 hr by leaf-dip bioassay | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1111086 | Insecticidal activity against Amphimallon majalis (European chafer) assessed as mortality after 10 days | 2010 | Pest management science, Jan, Volume: 66, Issue:1 | Variation in the laboratory susceptibility of turf-infesting white grubs (Coleoptera: Scarabaeidae) to biological, biorational and chemical control products. |
| AID1111961 | Resistance ratio, LC50 for Aphis gossypii F30 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1081818 | Drug metabolism in Drosophila melanogaster D.mel-2 cells over-expressing in CYP6G1 assessed as drug recovery measured 24 hr post dose by HPLC method | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1103855 | Toxicity against Neoseiulus fallacis in hop fields assessed as mortality | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1103851 | Insecticidal activity against 23 generation selection pressure-induced imidacloprid-resistance Nilaparvata lugens (brown planthopper) at third instar nymph stage in rice stem assessed as mortality treated for 30 secs prior to nymph infestation measured at | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Inheritance mode and realized heritability of resistance to imidacloprid in the brown planthopper, Nilaparvata lugens (Stål) (Homoptera: Delphacidae). |
| AID1632159 | Insecticidal activity against Plutella xylostella assessed as mortality at 100 ug/ml pre-incubated with cabbage leaves for 2 to 3 secs and measured 48 hrs post dose by leaf disc assay | 2016 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18 | Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety. |
| AID1104211 | Inhibition of Ceutorhynchus obstrictus development in canola pods of plant developed from compound treated seeds assessed as decrease in number of exit holes formed by larvae at 0.23 kg AI per 45.36 kg seeds relative to untreated control | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1112846 | Drug level in Urochloa mutica (buffalo grass) measured per gram of fresh weight at 89.7 kg/ha measured 28 days after treatment | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Effect of distribution and concentration of topically applied neonicotinoid insecticides in buffalograss, Buchloe dactyloides, leaf tissues on the differential mortality of Blissus occiduus under field conditions. |
| AID1081742 | Insecticidal activity against Nephotettix cincticeps (green rice leafhopper) assessed as lethality at 0.1 to 1 ppm | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Molecular design of dinotefuran with unique insecticidal properties. |
| AID1101290 | Retention time under neutral conditions using H20/MeOH (1:1) mobile phase by HPLC method | 2000 | Journal of agricultural and food chemistry, Dec, Volume: 48, Issue:12 | Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors. |
| AID1104183 | Synergistic ratio of LC50 for adult female Bemisia tabaci B-biotype NJ (sweet potato whitefly) to LC50 for adult female Bemisia tabaci B-biotype NJ in presence of 100 mg/L GSH depleter, DEM | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1111182 | Insecticidal activity against B-biotype thiamethoxam-resistant Bemisia tabaci (sweet potato whitefly) in cabbage leaf assessed as mortality after 48 hr by leaf disk assay | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Cross-resistance study and biochemical mechanisms of thiamethoxam resistance in B-biotype Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1101298 | Inhibition of [3H]IMI binding to Drosophila melanogaster neuronal acetylcholine receptor | 2000 | Journal of agricultural and food chemistry, Dec, Volume: 48, Issue:12 | Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors. |
| AID1081149 | Insecticidal activity against macropterous adult stage of imidaclopride-resistant Nilaparvata lugens (brown planthopper) assessed as concentration required to induce mortality per pest at 25 +/-1 degC applied topically to the prothorax notum of insect pri | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Divalent and oxabridged neonicotinoids constructed by dialdehydes and nitromethylene analogues of imidacloprid: design, synthesis, crystal structure, and insecticidal activities. |
| AID1112212 | Insecticidal activity against Popillia japonica at 552 g/kg SC assessed as reduction in leaf damage measured after 35 days by irrigation injection method (Rvb = 50.97 +/- 7.2 %) | 2012 | Pest management science, Apr, Volume: 68, Issue:4 | Soil application of neonicotinoid insecticides for control of insect pests in wine grape vineyards. |
| AID1090599 | Displacement of [3H]QNB from Drosophila melanogaster mAChR at 100000 nM by scintillation counting | 2007 | Journal of agricultural and food chemistry, Mar-21, Volume: 55, Issue:6 | Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists. |
| AID1081150 | Insecticidal activity against macropterous adult stage of imidaclopride-sensitive Nilaparvata lugens (brown planthopper) assessed as concentration required to induce mortality per pest at 25 +/-1 degC applied topically to the prothorax notum of insect pri | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Divalent and oxabridged neonicotinoids constructed by dialdehydes and nitromethylene analogues of imidacloprid: design, synthesis, crystal structure, and insecticidal activities. |
| AID1092037 | Binding affinity to Drosophila brain nicotinic acetylcholine receptor assessed as [3H]IMI binding by radioligand binding assay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Unique neonicotinoid binding conformations conferring selective receptor interactions. |
| AID1112225 | Insecticidal activity against Popillia japonica at 552 g/kg SC measured after 1 to 24 days by irrigation injection method | 2012 | Pest management science, Apr, Volume: 68, Issue:4 | Soil application of neonicotinoid insecticides for control of insect pests in wine grape vineyards. |
| AID1104209 | Inhibition of Ceutorhynchus obstrictus development in canola pods of plant developed from compound treated seeds assessed as decrease in number of exit holes formed by larvae at 0.38 kg AI per 45.36 kg seeds relative to untreated control | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1104732 | Resistance ratio of LC50 for Bemisia tabaci biotype-Q Q1 (sweet potato whitefly) to LC50 for Bemisia tabaci LABS | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID344087 | Displacement of [3H]nicotine from chick alpha4beta2 nAChR | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14 | Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche. |
| AID1103910 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as mortality treated using worst-case laboratory exposure procedure measured after 72 hr | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1082709 | Insecticidal activity against adult Aphis craccivora (cowpea aphid) assessed as larvicidal activity after 24 hr | 2012 | Journal of agricultural and food chemistry, Jan-11, Volume: 60, Issue:1 | Design, synthesis, and particular biological behaviors of chain-opening nitromethylene neonicotinoids with cis configuration. |
| AID1081793 | Insecticidal activity against imidacloprid-resistant Nilaparvata lugens (brown planthopper) assessed as drug concentration required to induce mortality per pest | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | cis-Configuration: a new tactic/rationale for neonicotinoid molecular design. |
| AID1091957 | Apparent permeability of the compound by PAMPA | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Importance of physicochemical properties for the design of new pesticides. |
| AID1081060 | Insecticidal activity against compound resistant second-instar larvae Nilaparvata lugens (brown planthopper) in compound rice seedlings assessed as toxicity at 25 degC measured after 6 days relative to control | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Synthesis, crystal structure, and insecticidal activities of highly congested hexahydroimidazo[1,2-a]pyridine derivatives: effect of conformation on activities. |
| AID1111987 | Insecticidal activity against cotton aphid Aphis gossypii F0 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1112938 | Insecticidal activity against Aphis craccivora (cowpea aphid) assessed as mortality at 500 mg/l | 2013 | Journal of agricultural and food chemistry, Jan-16, Volume: 61, Issue:2 | Pyrrole- and dihydropyrrole-fused neonicotinoids: design, synthesis, and insecticidal evaluation. |
| AID1110829 | Insecticidal activity against drug-resistant Bemisia tabaci GUAMIX (sweet potato whitefly) in cotton plant leaf assessed as mortality after 48 hr in presence of PBO pretreated 5 hr before compound challenge | 2009 | Pest management science, Feb, Volume: 65, Issue:2 | An analogue of piperonyl butoxide facilitates the characterisation of metabolic resistance. |
| AID1104689 | Toxicity against Rhopalosiphum padi infested wheat plant assessed as mortality at 1000 mg/l applied to upper plant for 1 min followed by basipetal transportation for 48 hr measured 24 hr after removal of upper plant parts relative to control | 2010 | Pest management science, Jul, Volume: 66, Issue:7 | Systemic action of novel neonicotinoid insecticide IPP-10 and its effect on the feeding behaviour of Rhopalosiphum padi on wheat. |
| AID1082238 | Inhibition of Oryctolagus cuniculus (rabbit) AOX in liver cytosol | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition. |
| AID1111077 | Insecticidal activity against Popillia japonica assessed as mortality after 10 days | 2010 | Pest management science, Jan, Volume: 66, Issue:1 | Variation in the laboratory susceptibility of turf-infesting white grubs (Coleoptera: Scarabaeidae) to biological, biorational and chemical control products. |
| AID1111960 | Resistance ratio, LC50 for Aphis gossypii F36 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1111959 | Resistance ratio, LC50 for Aphis gossypii F39 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1111984 | Insecticidal activity against cotton aphid Aphis gossypii F18 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1081817 | Activation of Drosophila melanogaster nicotinic acetylcholine receptor alpha2 expressed in Xenopus laevis co-expressing chicken nicotinic acetylcholine receptor beta2 subunit by electrophysiology method | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1112801 | Insecticidal activity against Frankliniella occidentalis TFA (western flower thrips) in compound treated sweet pepper leaf assessed as mortality at 150 mg/l at 25 +/- 2 degC by leaf dip method | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Thiamethoxam acts as a target-site synergist of spinosad in resistant strains of Frankliniella occidentalis. |
| AID1091971 | Insecticidal activity against Musca domestica (house fly) measured after intrathoracic compound injection in presence of cytochrome P450 inhibitor O-propyl O-(2-propynyl) phenylphosphonate | 2010 | Journal of agricultural and food chemistry, Nov-24, Volume: 58, Issue:22 | Furan-2,5-dimethylene-tethered bis-imidacloprid insecticide conferring high potency. |
| AID1111947 | Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as fecundity at LC20 concentration | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1104881 | Insecticidal activity against nymph stage of Bemisia tabaci (sweet potato whitefly) infested cotton leaves assessed as mortality at 0.375 mg ai/seed measured 10 to 40 days post germination under laboratory conditions relative to untreated control | 2011 | Pest management science, Feb, Volume: 67, Issue:2 | Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton. |
| AID1104691 | Toxicity against Rhopalosiphum padi infested wheat plant assessed as mortality at 1000 mg/l applied to upper plant for 1 min followed by basipetal transportation for 24 hr measured 24 hr after removal of upper plant parts relative to control | 2010 | Pest management science, Jul, Volume: 66, Issue:7 | Systemic action of novel neonicotinoid insecticide IPP-10 and its effect on the feeding behaviour of Rhopalosiphum padi on wheat. |
| AID1082237 | Inhibition of xanthine oxidase | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition. |
| AID1082423 | Insecticidal activity against Aphis craccivora (cowpea aphid) assessed as mortality at 250 mg/L after 24 hr by leaf-dip method | 2011 | Journal of agricultural and food chemistry, Oct-12, Volume: 59, Issue:19 | Design, synthesis, crystal structure analysis, and insecticidal evaluation of phenylazoneonicotinoids. |
| AID1091951 | Insecticidal activity against Nephotettix cincticeps (green rice leafhopper) in rice plant assessed as mortality at 100 mg/L insects released after 7 days of compound treatment measured after 24 hr of insect release | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery of imidacloprid and further developments from strategic molecular designs. |
| AID1081838 | Insecticidal activity against Aphis gossypii (cotton aphid) DAS lab strain by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1104201 | Resistance factor, ratio of LC50 for adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G15) to LC50 for adult female B-type Bemisia tabaci NJ | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID318725 | Displacement of [3H]ACE from Aplysia AChBP expressed in HEK293S cells by scintillation proximity assay | 2007 | Proceedings of the National Academy of Sciences of the United States of America, May-22, Volume: 104, Issue:21 | Mapping the elusive neonicotinoid binding site. |
| AID1101288 | Retention time under basic conditions using 20 mM Na2HPO4 (pH9.9)/MeOH (1:1) mobile phase by HPLC method | 2000 | Journal of agricultural and food chemistry, Dec, Volume: 48, Issue:12 | Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors. |
| AID1103897 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as corrected mortality at 0.1600/8 g AI/L treated using worst-case laboratory exposure procedure measured after 72 hr | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1082320 | Adulticidal activity against female Bemisia tabaci biotype B (sweet potato whitefly) in cucumber leaves assessed as residual contact toxicity treated for 30 secs before adult insect infestation measured after 24 hr by leaf dip bioassay | 2011 | Journal of agricultural and food chemistry, Aug-10, Volume: 59, Issue:15 | Adulticidal activity of phthalides identified in Cnidium officinale rhizome to B- and Q-biotypes of Bemisia tabaci. |
| AID1632165 | Acaricidal activity against Tetranychus cinnabarinus assessed as mortality at 100 ug/ml pre-incubated with mite-infested Sieva bean plants for 3 secs and measured 48 hrs post dose | 2016 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18 | Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety. |
| AID1104872 | Insecticidal activity against adult Bemisia tabaci (sweet potato whitefly) infested cotton leaves assessed as decrease in egg production at 0.375 mg ai/seed measured 10 to 40 days post germination under green house conditions relative to untreated control | 2011 | Pest management science, Feb, Volume: 67, Issue:2 | Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton. |
| AID1091960 | Neuroblocking activity in Periplaneta americana (American cockroach) nicotinic acetylcholine receptor in abdominal fifth and sixth ganglia nerve assessed as neuroblocking concentration by neurophysiological test | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Importance of physicochemical properties for the design of new pesticides. |
| AID1111948 | Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as longevity at LC20 concentration | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1104200 | Resistance factor, ratio of LC50 for adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) to LC50 for adult female B-type Bemisia tabaci NJ | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID145345 | Potency to displace [3H]IMI binding to Nicotinic acetylcholine receptor from Drosophila head membranes | 2002 | Journal of medicinal chemistry, Jun-20, Volume: 45, Issue:13 | Structural features of azidopyridinyl neonicotinoid probes conferring high affinity and selectivity for mammalian alpha4beta2 and Drosophila nicotinic receptors. |
| AID1101289 | Retention time under acidic conditions using H20/MeOH mobile phase containing 0.1% TFA (1:1) by HPLC method | 2000 | Journal of agricultural and food chemistry, Dec, Volume: 48, Issue:12 | Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors. |
| AID1103894 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as corrected mortality at 0.1600/32 g AI/L treated using worst-case laboratory exposure procedure measured after 72 hr | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1090602 | Displacement of [3H]AF-DX 384 from Drosophila melanogaster mAChR by scintillation counting | 2007 | Journal of agricultural and food chemistry, Mar-21, Volume: 55, Issue:6 | Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists. |
| AID1104205 | Inhibition of Contarinia nasturtii larval development in Brassica oleracea L. var italica plant developed from compound pretreated seeds at 4.5 g AI per 100 g seed measured at 4-5 weeks after planting | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1112220 | Insecticidal activity against Popillia japonica at 552 g/kg SC assessed as moribund behaviour measured after 3 days by irrigation injection method | 2012 | Pest management science, Apr, Volume: 68, Issue:4 | Soil application of neonicotinoid insecticides for control of insect pests in wine grape vineyards. |
| AID1103913 | Ovicidal activity against Metaseiulus occidentalis eggs in bean leaf disk infested with two-spotted spider mites assessed as corrected cumulative mortality at 240 g/L SC formulation treated using worst-case laboratory exposure procedure measured after 144 | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1460875 | Insecticidal activity against Rhodobium porosum adults placed on 5 secs compound pre-treated bean leaves after 1 day by leaf dipping protocol based method | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | Indole Alkaloids from Hunteria zeylanica. |
| AID1111970 | Resistance ratio, LC50 for Aphis gossypii F6 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID147718 | Binding affinity for nAChR with [3H]imidacloprid in Myzus persicae | 2000 | Journal of medicinal chemistry, Dec-28, Volume: 43, Issue:26 | 5-Azidoimidacloprid and an acyclic analogue as candidate photoaffinity probes for mammalian and insect nicotinic acetylcholine receptors. |
| AID1091945 | Insecticidal activity against Nephotettix cincticeps (green rice leafhopper) assessed as mortality measured after 4 days | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery of imidacloprid and further developments from strategic molecular designs. |
| AID1082241 | Phytotoxicity against Zea mays (maize) seedlings assessed as lesions at 50 to 100 ppm after 9 days | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition. |
| AID1111076 | Insecticidal activity against Popillia japonica assessed as mortality after 20 days | 2010 | Pest management science, Jan, Volume: 66, Issue:1 | Variation in the laboratory susceptibility of turf-infesting white grubs (Coleoptera: Scarabaeidae) to biological, biorational and chemical control products. |
| AID1112868 | Insecticidal activity against first generation Blissus occiduus in buffalograss under field condition assessed as reduction in number at 9.6 kg/ha measured 106 days after treatment | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Effect of distribution and concentration of topically applied neonicotinoid insecticides in buffalograss, Buchloe dactyloides, leaf tissues on the differential mortality of Blissus occiduus under field conditions. |
| AID1090558 | Toxic effect in Periplaneta americana (American cockroach) assessed as paralyzed insects after 24 hr of abdomen compound injection by insecticidal assay | 2007 | Journal of agricultural and food chemistry, Feb-07, Volume: 55, Issue:3 | Insecticidal and neuroblocking potencies of variants of the imidazolidine moiety of imidacloprid-related neonicotinoids and the relationship to partition coefficient and charge density on the pharmacophore. |
| AID1111966 | Resistance ratio, LC50 for Aphis gossypii F18 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1092034 | Binding affinity to freshwater snail Lymnaea stagnalis AChBP assessed as [3H]EPI binding by radioligand binding assay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Unique neonicotinoid binding conformations conferring selective receptor interactions. |
| AID1103900 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as corrected mortality at 0.1600 g AI/L treated using worst-case laboratory exposure procedure measured after 72 hr | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1104189 | Insecticidal activity against adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G15) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay in presence of 100 | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1111953 | Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as reduction in body weight at LC20 concentration measured after 24 hr by dipping method (Rvb = 0.33 +/- 0.0004 mg/aphid) | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1080612 | Insecticidal activity against adult Aphis gossypii (cotton aphid) in cucumber cotyledons assessed as mortality at 500 ppm treated for 5 secs before adult infestation measured after 72 hr | 2009 | Journal of agricultural and food chemistry, Mar-25, Volume: 57, Issue:6 | Neonicotinoid substituents forming a water bridge at the nicotinic acetylcholine receptor. |
| AID1104746 | Insecticidal activity against Bemisia tabaci biotype-Q Q2 (sweet potato whitefly) after 48 hr by leaf-dip bioassay | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1112209 | Insecticidal activity against Popillia japonica assessed as reduction in leaf damage measured up to 63 days post treatment by laboratory bioassay | 2012 | Pest management science, Apr, Volume: 68, Issue:4 | Soil application of neonicotinoid insecticides for control of insect pests in wine grape vineyards. |
| AID1082228 | Insecticidal activity against Nilaparvata lugens (brown planthopper) assessed as mortality at 20 mg/l after 72 hr | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Synthesis, insecticidal activity, and molecular docking studies of nitenpyram analogues with a flexible ester arm anchored on tetrahydropyrimidine ring. |
| AID1081063 | Insecticidal activity against compound sensitive second-instar larvae Nilaparvata lugens (brown planthopper) in compound rice seedlings assessed as mortality at 25 degC measured after 6 days | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Synthesis, crystal structure, and insecticidal activities of highly congested hexahydroimidazo[1,2-a]pyridine derivatives: effect of conformation on activities. |
| AID1081062 | Insecticidal activity against compound resistant second-instar larvae Nilaparvata lugens (brown planthopper) in compound rice seedlings assessed as mortality at 25 degC measured after 6 days | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Synthesis, crystal structure, and insecticidal activities of highly congested hexahydroimidazo[1,2-a]pyridine derivatives: effect of conformation on activities. |
| AID1104876 | Insecticidal activity against adult Bemisia tabaci (sweet potato whitefly) infested cotton leaves assessed as increase in mortality at 0.375 mg ai/seed measured 10 to 40 days post germination under green house conditions relative to untreated control | 2011 | Pest management science, Feb, Volume: 67, Issue:2 | Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton. |
| AID1091948 | Insecticidal activity against Nephotettix cincticeps (green rice leafhopper) in rice plant assessed as mortality at 100 mg/L insects released after 3 days of compound treatment measured after 24 hr of insect release | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery of imidacloprid and further developments from strategic molecular designs. |
| AID1091505 | Insecticidal activity against Tetranychus cinnabarinus (carmine spider mite) in soybean tender shoots assessed as mortality at 0.2 mg/ml treated for 5 secs measured after 48 hr | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22 | Synthesis and biological activities of novel pyrazole oxime derivatives containing a 2-chloro-5-thiazolyl moiety. |
| AID1101295 | Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta1 nicotinic acetylcholine receptor subunits | 2000 | Journal of agricultural and food chemistry, Dec, Volume: 48, Issue:12 | Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors. |
| AID1081841 | Insecticidal activity against Myzus persicae (green peach aphid) DAS lab strain by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1112841 | Insecticidal activity against first generation Blissus occiduus in buffalograss under field condition assessed as reduction in number at 9.6 kg/ha measured 3 days after treatment | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Effect of distribution and concentration of topically applied neonicotinoid insecticides in buffalograss, Buchloe dactyloides, leaf tissues on the differential mortality of Blissus occiduus under field conditions. |
| AID1081747 | Insecticidal activity against Laodelphax striatella (small brown planthopper) assessed as lethality at 0.1 to 1 ppm | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Molecular design of dinotefuran with unique insecticidal properties. |
| AID1091988 | Insecticidal activity against Aphis medicaginis assessed as insect mortality at 500 mg/L measured after 72 hr post compound treatment | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Chiral 1,5-disubstituted 1,3,5-hexahydrotriazine-2-N-nitroimine analogues as novel potent neonicotinoids: Synthesis, insecticidal evaluation and molecular docking studies. |
| AID1111951 | Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as reduction in body weight at LC20 concentration measured after 48 hr by dipping method (Rvb = 0.36 +/- 0.0006 mg/aphid) | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1112855 | Drug level in Urochloa mutica (buffalo grass) measured per gram of fresh weight at 89.7 kg/ha measured 3 days after treatment | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Effect of distribution and concentration of topically applied neonicotinoid insecticides in buffalograss, Buchloe dactyloides, leaf tissues on the differential mortality of Blissus occiduus under field conditions. |
| AID1104879 | Insecticidal activity against adult Bemisia tabaci (sweet potato whitefly) infested cotton leaves assessed as decrease in egg deposition at 0.375 mg ai/seed measured 10 to 40 days post germination under laboratory conditions relative to untreated control | 2011 | Pest management science, Feb, Volume: 67, Issue:2 | Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton. |
| AID1081828 | Resistance index, ratio of LC50 for drug resistant Myzus persicae R-4013A (green peach aphid) to LC50 for Myzus persicae S-USIL | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1082422 | Insecticidal activity against Aphis craccivora (cowpea aphid) assessed as mortality at 125 mg/L after 24 hr by leaf-dip method | 2011 | Journal of agricultural and food chemistry, Oct-12, Volume: 59, Issue:19 | Design, synthesis, crystal structure analysis, and insecticidal evaluation of phenylazoneonicotinoids. |
| AID1110825 | Insecticidal activity against drug-resistant Bemisia tabaci GUAMIX (sweet potato whitefly) in cotton plant leaf assessed as mortality after 48 hr in presence of EN 16/5-1 pretreated 5 hr before compound challenge | 2009 | Pest management science, Feb, Volume: 65, Issue:2 | An analogue of piperonyl butoxide facilitates the characterisation of metabolic resistance. |
| AID1111962 | Resistance ratio, LC50 for Aphis gossypii F33 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1104868 | Drug uptake in Gossypium hirsutum (cotton) cotyledon at 0.375 mg ai/seed measured 10 days post germination under green house conditions | 2011 | Pest management science, Feb, Volume: 67, Issue:2 | Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton. |
| AID1110828 | Insecticidal activity against drug-susceptible Bemisia tabaci SUD-S (sweet potato whitefly) in cotton plant leaf assessed as mortality after 48 hr in presence of PBO pretreated 5 hr before compound challenge | 2009 | Pest management science, Feb, Volume: 65, Issue:2 | An analogue of piperonyl butoxide facilitates the characterisation of metabolic resistance. |
| AID1103852 | Insecticidal activity against third instar nymph stage of imidacloprid-susceptible Nilaparvata lugens (brown planthopper) in rice stem assessed as mortality treated for 30 secs prior to nymph infestation measured at 96 hr post-drug treatment by rice-stem | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Inheritance mode and realized heritability of resistance to imidacloprid in the brown planthopper, Nilaparvata lugens (Stål) (Homoptera: Delphacidae). |
| AID227700 | Anticonvulsant activity | 2003 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 13, Issue:16 | Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity. |
| AID1104184 | Synergistic ratio of LC50 for adult female Bemisia tabaci B-biotype NJ (sweet potato whitefly) to LC50 for adult female Bemisia tabaci B-biotype NJ in presence of 100 mg/L cytochrome P450 monoxygenase inhibitor, PBO | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1111975 | Insecticidal activity against cotton aphid Aphis gossypii F42 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1091503 | Insecticidal activity against Aphis medicaginis in soybean tender shoots assessed as mortality at 0.5 mg/ml treated for 5 secs measured after 48 hr | 2008 | Journal of agricultural and food chemistry, Nov-26, Volume: 56, Issue:22 | Synthesis and biological activities of novel pyrazole oxime derivatives containing a 2-chloro-5-thiazolyl moiety. |
| AID1111968 | Resistance ratio, LC50 for Aphis gossypii F12 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1103853 | Toxicity against Amblyseius andersoni in hop fields assessed as mortality | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID1104187 | Insecticidal activity against adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay in presence of 100 | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1104730 | Resistance ratio of LC50 for Bemisia tabaci biotype-Q Q3 (sweet potato whitefly) to LC50 for Bemisia tabaci LABS | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1081825 | Resistance index, ratio of LC50 for rothamsted-resistant Bemisia tabaci Q-biotype R-4971BT9 (sweet potato whitefly) to LC50 for Bemisia tabaci S-4971BT1 | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1101020 | Displacement of [3H]IMI from nicotinic acetylcholine receptor in Drosophila melanogaster head membrane after 90 min by filter binding assay | 2000 | Journal of neurochemistry, Sep, Volume: 75, Issue:3 | Insect nicotinic acetylcholine receptor: conserved neonicotinoid specificity of [(3)H]imidacloprid binding site. |
| AID1104191 | Insecticidal activity against adult female Bemisia tabaci B-biotype NJ (sweet potato whitefly) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay in presence of 100 mg/L este | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1104177 | Synergistic ratio of LC50 for adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) to LC50 for adult female Bemisia tabaci B-biotype NJ in presence of 100 mg/L GSH depleter, DEM | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1112013 | Termiticidal activity against Reticulitermes flavipes at 0.69 ug/g after 7 days by forced exposure test | 2012 | Pest management science, Jan, Volume: 68, Issue:1 | Bifenthrin longevity at the termiticidal application rate. |
| AID1081151 | Insecticidal activity against apterous adult stage of Aphis craccivora (cowpea aphid) in horsebean leaves assessed as mortality at 500 mg/l at 25 +/-1 degC treated for 5 secs measured after 24 hr by leaf-dip method | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Divalent and oxabridged neonicotinoids constructed by dialdehydes and nitromethylene analogues of imidacloprid: design, synthesis, crystal structure, and insecticidal activities. |
| AID1081283 | Insecticidal activity against apterous adult stage of Aphis fabae ( black bean aphids) in soybean tender shoots assessed as death rate at 200 mg/l treated for 5 secs measured after 48 hr by modified FAO dip test | 2010 | Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3 | Synthesis and insecticidal evaluation of N-tert-butyl-N'-thio[1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine]-N,N'-diacylhydrazines. |
| AID1082322 | Adulticidal activity against female Bemisia tabaci biotype Q (sweet potato whitefly) in cucumber leaves assessed as residual contact toxicity treated for 30 secs before adult insect infestation measured after 24 hr by leaf dip bioassay | 2011 | Journal of agricultural and food chemistry, Aug-10, Volume: 59, Issue:15 | Adulticidal activity of phthalides identified in Cnidium officinale rhizome to B- and Q-biotypes of Bemisia tabaci. |
| AID1632163 | Insecticidal activity against Aphis craccivora assessed as mortality at 50 ug/ml pre-incubated with horsebean shoot with aphids for 2 secs and measured 48 hrs post dose by foliar application method | 2016 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18 | Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety. |
| AID1104740 | Insecticidal activity against Bemisia tabaci biotype-B B4 (sweet potato whitefly) after 48 hr by leaf-dip bioassay | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1104204 | Insecticidal activity against adult female imidacloprid-susceptible Bemisia tabaci B-biotype NJ (sweet potato whitefly) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1104199 | Insecticidal activity against adult male Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1081827 | Resistance index, ratio of LC50 for DAS insecticide-resistant Bemisia tabaci B-biotype R-PB (sweet potato whitefly) to LC50 for drug sensitive Bemisia tabaci DAS lab strain | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID288191 | Membrane retention in permeability experiment with artificial membrane | 2007 | Bioorganic & medicinal chemistry, Jun-01, Volume: 15, Issue:11 | QSAR study on permeability of hydrophobic compounds with artificial membranes. |
| AID1091954 | Insecticidal activity against Nephotettix cincticeps (green rice leafhopper) in rice plant assessed as mortality at 100 mg/L insects released after 14 days of compound treatment measured after 24 hr of insect release | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery of imidacloprid and further developments from strategic molecular designs. |
| AID1101297 | Toxicity in ip dosed Mus musculus (mouse) | 2000 | Journal of agricultural and food chemistry, Dec, Volume: 48, Issue:12 | Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors. |
| AID344091 | Insecticidal activity against intrathoracically dosed houseflies at >10 um/g | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14 | Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche. |
| AID1091956 | Apparent hydrophobicity, log D of the compound in Octanol-buffer | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Importance of physicochemical properties for the design of new pesticides. |
| AID1104207 | Inhibition of Ceutorhynchus obstrictus development in canola pods of plant developed from compound treated seeds assessed as decrease in number of exit holes formed by larvae at 0.28 kg AI per 45.36 kg seeds | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1112223 | Insecticidal activity against Popillia japonica at 552 g/kg SC measured after 14 days by irrigation injection method | 2012 | Pest management science, Apr, Volume: 68, Issue:4 | Soil application of neonicotinoid insecticides for control of insect pests in wine grape vineyards. |
| AID1081152 | Insecticidal activity against apterous adult stage of Aphis craccivora (cowpea aphid) in horsebean leaves assessed as mortality at 25 +/-1 degC treated for 5 secs measured after 24 hr by leaf-dip method | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Divalent and oxabridged neonicotinoids constructed by dialdehydes and nitromethylene analogues of imidacloprid: design, synthesis, crystal structure, and insecticidal activities. |
| AID1112803 | Insecticidal activity against Frankliniella occidentalis TFB (western flower thrips) in compound treated sweet pepper leaf assessed as mortality at 150 mg/l at 25 +/- 2 degC by leaf dip method | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Thiamethoxam acts as a target-site synergist of spinosad in resistant strains of Frankliniella occidentalis. |
| AID1083116 | Pesticidal activity against Aphis gossypii (cotton aphid) third-instar nymphae grown on tender Hibiscus syriacus leaves assessed as pest mortality at 2 mg/L measured 24 hr post compound exposure | 2012 | Journal of agricultural and food chemistry, Nov-07, Volume: 60, Issue:44 | Synthesis and bioactivity study of 2-acylamino-substituted N'-benzylbenzohydrazide derivatives. |
| AID145517 | Binding affinity for nAChR with [3H]nicotine in rat brain | 2000 | Journal of medicinal chemistry, Dec-28, Volume: 43, Issue:26 | 5-Azidoimidacloprid and an acyclic analogue as candidate photoaffinity probes for mammalian and insect nicotinic acetylcholine receptors. |
| AID1110830 | Insecticidal activity against drug-susceptible Bemisia tabaci SUD-S (sweet potato whitefly) in cotton plant leaf assessed as mortality after 48 hr in presence of EN 16/5-1 pretreated 5 hr before compound challenge | 2009 | Pest management science, Feb, Volume: 65, Issue:2 | An analogue of piperonyl butoxide facilitates the characterisation of metabolic resistance. |
| AID1104178 | Synergistic ratio of LC50 for adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30) to LC50 for adult female Bemisia tabaci B-biotype NJ in presence of 100 mg/L cytochrome P450 monoxygenase inhibitor, PBO | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1104742 | Insecticidal activity against Bemisia tabaci biotype-B B3 (sweet potato whitefly) after 48 hr by leaf-dip bioassay | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1081285 | Larvicidal activity against fourth-instar larval stage of Mythimna separata (Oriental armyworm) in compound-pretreated corn leaves assessed as mortality at 10 mg/l after 4 days | 2010 | Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3 | Synthesis and insecticidal evaluation of N-tert-butyl-N'-thio[1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine]-N,N'-diacylhydrazines. |
| AID1080505 | Insecticidal activity against Mythimna separata(Oriental armyworm) second-instar larvae infested on compound pre-treated corn leaves assessed as insect mortality measured 48 hr post compound treatment by leaf-dip method | 2009 | Journal of agricultural and food chemistry, Feb-11, Volume: 57, Issue:3 | Design, synthesis, and insecticidal activities of novel analogues of neonicotinoids: replacement of nitromethylene with nitroconjugated system. |
| AID1111950 | Insecticidal activity against imidacloprid-resistant Aphis gossypii (cotton aphid) in cotton leaves assessed as reduction in body weight at LC20 concentration measured after 72 hr by dipping method (Rvb = 0.40 +/- 0.0002 mg/aphid) | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1112219 | Insecticidal activity against Popillia japonica at 552 g/kg SC assessed as moribund behaviour measured after 10 to 19 days by irrigation injection method | 2012 | Pest management science, Apr, Volume: 68, Issue:4 | Soil application of neonicotinoid insecticides for control of insect pests in wine grape vineyards. |
| AID1112221 | Insecticidal activity against Popillia japonica at 552 g/kg SC assessed as moribund behaviour measured after 24 to 56 days by irrigation injection method | 2012 | Pest management science, Apr, Volume: 68, Issue:4 | Soil application of neonicotinoid insecticides for control of insect pests in wine grape vineyards. |
| AID1103850 | Insecticidal activity against Nilaparvata lugens (brown planthopper) F1 progeny generated from reciprocal cross between female imidacloprid-susceptible strain and male imidaclporid-resistant strain in rice stem assessed as mortality treated for 30 secs pr | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Inheritance mode and realized heritability of resistance to imidacloprid in the brown planthopper, Nilaparvata lugens (Stål) (Homoptera: Delphacidae). |
| AID1104688 | Toxicity against Rhopalosiphum padi infested wheat plant assessed as mortality at 1000 mg/l applied to upper plant for 1 min followed by basipetal transportation for 48 hr measured 48 hr after removal of upper plant parts relative to control | 2010 | Pest management science, Jul, Volume: 66, Issue:7 | Systemic action of novel neonicotinoid insecticide IPP-10 and its effect on the feeding behaviour of Rhopalosiphum padi on wheat. |
| AID1112862 | Insecticidal activity against second generation Blissus occiduus in buffalograss under field condition assessed as reduction in number at 9.6 kg/ha measured 7 days after treatment | 2013 | Pest management science, Feb, Volume: 69, Issue:2 | Effect of distribution and concentration of topically applied neonicotinoid insecticides in buffalograss, Buchloe dactyloides, leaf tissues on the differential mortality of Blissus occiduus under field conditions. |
| AID1111983 | Insecticidal activity against cotton aphid Aphis gossypii F15 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1091950 | Insecticidal activity against Nephotettix cincticeps (green rice leafhopper) in rice plant assessed as mortality at 100 mg/L insects released after 3 days of compound treatment measured after 72 hr of insect release (Rvb = 0%) | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery of imidacloprid and further developments from strategic molecular designs. |
| AID1104179 | Synergistic ratio of LC50 for adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G15)to LC50 for adult female Bemisia tabaci B-biotype NJ in presence of 100 mg/L esterase inhibitor, DEF | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1111982 | Insecticidal activity against cotton aphid Aphis gossypii F21 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1111075 | Insecticidal activity against Popillia japonica assessed as mortality after 30 days | 2010 | Pest management science, Jan, Volume: 66, Issue:1 | Variation in the laboratory susceptibility of turf-infesting white grubs (Coleoptera: Scarabaeidae) to biological, biorational and chemical control products. |
| AID323211 | Insecticidal activity against Aphis gossypii glover in cotton/melon plant | 2008 | Bioorganic & medicinal chemistry, Mar-15, Volume: 16, Issue:6 | Synthesis of insecticidal fluorinated anthranilic diamides. |
| AID371214 | Insecticidal activity against imidacloprid-sensitive Nilaparvata lugens | 2008 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 18, Issue:24 | cis-Nitromethylene neonicotinoids as new nicotinic family: synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-alpha]pyridine. |
| AID1110823 | Resistant factor, ratio of LC50 for drug-susceptible Bemisia tabaci SUD-S (sweet potato whitefly) to LC50 for drug-resistant Bemisia tabaci GUAMIX (sweet potato whitefly) in presence of PBO | 2009 | Pest management science, Feb, Volume: 65, Issue:2 | An analogue of piperonyl butoxide facilitates the characterisation of metabolic resistance. |
| AID1090571 | Insecticidal activity against Aphis craccivora (cowpea aphid) assessed as mortality measured after 24 hr | 2007 | Journal of agricultural and food chemistry, Mar-21, Volume: 55, Issue:6 | Synthesis, insecticidal activity, and QSAR of novel nitromethylene neonicotinoids with tetrahydropyridine fixed cis configuration and exo-ring ether modification. |
| AID1111183 | Insecticidal activity against B-biotype thiamethoxam-sensitive Bemisia tabaci (sweet potato whitefly) in cabbage leaf assessed as mortality after 48 hr by leaf disk assay | 2010 | Pest management science, Mar, Volume: 66, Issue:3 | Cross-resistance study and biochemical mechanisms of thiamethoxam resistance in B-biotype Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID318726 | Displacement of [3H]EPI from Aplysia AChBP expressed in HEK293S cells by scintillation proximity assay | 2007 | Proceedings of the National Academy of Sciences of the United States of America, May-22, Volume: 104, Issue:21 | Mapping the elusive neonicotinoid binding site. |
| AID318727 | Inhibition of [3H]1-((5-azido-6-chloropyridin-3-yl)methyl)-3-methyl-2-nitroguanidine incorporation into AchBP assessed as protection of photoaffinity labeling at 500 pmol | 2007 | Proceedings of the National Academy of Sciences of the United States of America, May-22, Volume: 104, Issue:21 | Mapping the elusive neonicotinoid binding site. |
| AID1104212 | Inhibition of Ceutorhynchus obstrictus development in canola pods of plant developed from compound treated seeds assessed as decrease in number of exit holes formed by larvae at 0.45 kg AI per 45.36 kg seeds | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1081842 | Insecticidal activity against Bemisia tabaci S-4971BT1 (sweet potato whitefly) by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1111981 | Insecticidal activity against cotton aphid Aphis gossypii F24 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1111079 | Insecticidal activity against Maladera castanea assessed as mortality after 30 days | 2010 | Pest management science, Jan, Volume: 66, Issue:1 | Variation in the laboratory susceptibility of turf-infesting white grubs (Coleoptera: Scarabaeidae) to biological, biorational and chemical control products. |
| AID1081833 | Insecticidal activity against DAS-susceptible Bemisia tabaci S-4971BT1 (sweet potato whitefly) by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID344080 | Toxicity in ip dosed Swiss Webster mouse | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14 | Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche. |
| AID1081147 | Toxicity ratio of imidacloprid LC50 to compound LC50 for macropterous adult stage of imidaclopride-resistant Nilaparvata lugens (brown planthopper) after 48 hr by microtopical application technique | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Divalent and oxabridged neonicotinoids constructed by dialdehydes and nitromethylene analogues of imidacloprid: design, synthesis, crystal structure, and insecticidal activities. |
| AID1101022 | Displacement of [3H]IMI from nicotinic acetylcholine receptor in Aphis craccivora (cowpea aphid) whole body membrane after 90 min by filter binding assay | 2000 | Journal of neurochemistry, Sep, Volume: 75, Issue:3 | Insect nicotinic acetylcholine receptor: conserved neonicotinoid specificity of [(3)H]imidacloprid binding site. |
| AID1081835 | Insecticidal activity against drug sensitive Bemisia tabaci DAS (sweet potato whitefly) lab strain by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1104863 | Insecticidal activity against Diaphorina citri infected with Candidatus Liberibacter asiaticus assessed as mortality after 48 hr | 2011 | Pest management science, Jan, Volume: 67, Issue:1 | Effect of Candidatus Liberibacter asiaticus infection on susceptibility of Asian citrus psyllid, Diaphorina citri, to selected insecticides. |
| AID1081821 | Insecticidal activity against Myzus persicae (green peach aphid) infested UV irradiated leaves of pepper plant exposed to compound at 124 ppm assessed as insect control efficacy post 3 days UV exposure relative to untreated control | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1081064 | Insecticidal activity against second-instar larvae Mythimna separata (Oriental armyworm) in compound treated corn leaves assessed as mortality measured after 48 hr | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Synthesis, crystal structure, and insecticidal activities of highly congested hexahydroimidazo[1,2-a]pyridine derivatives: effect of conformation on activities. |
| AID1104190 | Insecticidal activity against adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G15) in cotton leaf discs assessed as mortality treated for 10 secs prior to adult infestation measured after 72 hr by leaf-dip bioassay in presence of 100 | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1104180 | Synergistic ratio of LC50 for adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G15) to LC50 for adult female Bemisia tabaci B-biotype NJ in presence of 100 mg/L GSH depleter, DEM | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1104878 | Insecticidal activity against adult Bemisia tabaci (sweet potato whitefly) infested cotton leaves assessed as effect on laid eggs at 0.375 mg ai/seed measured 10 to 40 days post germination under laboratory conditions relative to untreated control | 2011 | Pest management science, Feb, Volume: 67, Issue:2 | Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton. |
| AID352729 | Octanol-water partition coefficient, log P of the compound | 2009 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 19, Issue:11 | Crown-capped imidacloprid: a novel design and insecticidal activity. |
| AID323214 | Insecticidal activity against Aphis gossypii glover in cotton/melon plant by contact plant assay | 2008 | Bioorganic & medicinal chemistry, Mar-15, Volume: 16, Issue:6 | Synthesis of insecticidal fluorinated anthranilic diamides. |
| AID1111965 | Resistance ratio, LC50 for Aphis gossypii F24 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1632158 | Insecticidal activity against Plutella xylostella assessed as mortality at 200 ug/ml pre-incubated with cabbage leaves for 2 to 3 secs and measured 48 hrs post dose by leaf disc assay | 2016 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 26, Issue:18 | Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety. |
| AID1104198 | Insecticidal activity against female F1 progeny generated from reciprocal cross between female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) with male Bemisia tabaci B-biotype NJ in cotton leaf discs assessed as mortality treated for 10 secs pri | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1090600 | Displacement of [3H]AF-DX 384 from Drosophila melanogaster mAChR at 100000 nM by scintillation counting | 2007 | Journal of agricultural and food chemistry, Mar-21, Volume: 55, Issue:6 | Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists. |
| AID1104744 | Insecticidal activity against Bemisia tabaci biotype-Q Q3 (sweet potato whitefly) after 48 hr by leaf-dip bioassay | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1104727 | Resistance ratio of LC50 for Bemisia tabaci biotype-B B3 (sweet potato whitefly) to LC50 for Bemisia tabaci LABS | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID1104219 | Inhibition of Ceutorhynchus obstrictus preimaginal development in Brassica napus L. Ryder pods of plant developed from compound treated seeds assessed as decrease in number of exit holes formed per pod by larvae at 800 g/L FS | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1090758 | Insecticidal activity against Myzus persicae (green peach aphid) assessed as insect mortality at 50 ppm | 2007 | Journal of agricultural and food chemistry, Sep-05, Volume: 55, Issue:18 | Structure-activity relationship development of dihaloaryl triazole compounds as insecticides and acaricides. 1. Phenyl thiophen-2-yl triazoles. |
| AID1103848 | Insecticidal activity against Nilaparvata lugens (brown planthopper) parental generation in rice stem assessed as mortality treated for 30 secs prior to nymph infestation measured at 96 hr post-drug treatment by rice-stem dipping method | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Inheritance mode and realized heritability of resistance to imidacloprid in the brown planthopper, Nilaparvata lugens (Stål) (Homoptera: Delphacidae). |
| AID1090601 | Displacement of [3H]QNB from Drosophila melanogaster mAChR by scintillation counting | 2007 | Journal of agricultural and food chemistry, Mar-21, Volume: 55, Issue:6 | Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists. |
| AID1102411 | Neuroblocking potency against Periplaneta americana (American cockroach) abdominal central nerve cord assessed as compound concentration at which the frequency first reduced below 10 counts/30 secs within 30 min after compound treatment initiation by elec | 2003 | Bioscience, biotechnology, and biochemistry, May, Volume: 67, Issue:5 | Asymmetric chloronicotinyl insecticide, 1-[1-(6-chloro-3-pyridyl)ethyl]-2-nitroiminoimidazolidine: preparation, resolution and biological activities toward insects and their nerve preparations. |
| AID1082229 | Insecticidal activity against Nilaparvata lugens (brown planthopper) assessed as mortality at 100 mg/l after 72 hr | 2011 | Journal of agricultural and food chemistry, May-11, Volume: 59, Issue:9 | Synthesis, insecticidal activity, and molecular docking studies of nitenpyram analogues with a flexible ester arm anchored on tetrahydropyrimidine ring. |
| AID1101296 | Toxicity against Musca domestica (house fly) dosed with compound through intra-thoracic injection pre-treated with 100 ug/g metabolic detoxification inhibitor O-propyl O-(2-propynyl)phenylphosphonate | 2000 | Journal of agricultural and food chemistry, Dec, Volume: 48, Issue:12 | Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors. |
| AID1111083 | Insecticidal activity against Anomala orientalis assessed as mortality after 10 days | 2010 | Pest management science, Jan, Volume: 66, Issue:1 | Variation in the laboratory susceptibility of turf-infesting white grubs (Coleoptera: Scarabaeidae) to biological, biorational and chemical control products. |
| AID1082421 | Insecticidal activity against Aphis craccivora (cowpea aphid) assessed as mortality after 24 hr by leaf-dip method | 2011 | Journal of agricultural and food chemistry, Oct-12, Volume: 59, Issue:19 | Design, synthesis, crystal structure analysis, and insecticidal evaluation of phenylazoneonicotinoids. |
| AID1091970 | Displacement of [3H]IMI from Musca domestica (house fly) brain nicotinic acetylcholine receptor | 2010 | Journal of agricultural and food chemistry, Nov-24, Volume: 58, Issue:22 | Furan-2,5-dimethylene-tethered bis-imidacloprid insecticide conferring high potency. |
| AID1081066 | Insecticidal activity against Aphis craccivora (cowpea aphid) in compound treated horsebean plant leaves assessed as mortality measured after 24 hr by leaf-dip method | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Synthesis, crystal structure, and insecticidal activities of highly congested hexahydroimidazo[1,2-a]pyridine derivatives: effect of conformation on activities. |
| AID1111969 | Resistance ratio, LC50 for Aphis gossypii F9 (cotton aphid) to LC50 for Aphis gossypii F0 | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1111955 | Insecticidal activity against imidacloprid-resistant Aphis gossypii RF45 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1090559 | Neuroblocking activity in Periplaneta americana (American cockroach) nicotinic acetylcholine receptor in abdominal fifth and sixth ganglia nerve assessed as neuroblocking concentration by neurophysiological test | 2007 | Journal of agricultural and food chemistry, Feb-07, Volume: 55, Issue:3 | Insecticidal and neuroblocking potencies of variants of the imidazolidine moiety of imidacloprid-related neonicotinoids and the relationship to partition coefficient and charge density on the pharmacophore. |
| AID1081153 | Insecticidal activity against second instar larval stage of Mythimna separata (Oriental armyworm) in compound pretreated corn leaves assessed as mortality at 500 mg/l at 25 +/-1 degC after 48 hr | 2010 | Journal of agricultural and food chemistry, Mar-10, Volume: 58, Issue:5 | Divalent and oxabridged neonicotinoids constructed by dialdehydes and nitromethylene analogues of imidacloprid: design, synthesis, crystal structure, and insecticidal activities. |
| AID1101023 | Displacement of [3H]IMI from nicotinic acetylcholine receptor in Myzus persicae (green peach aphid) whole body membrane after 90 min by filter binding assay | 2000 | Journal of neurochemistry, Sep, Volume: 75, Issue:3 | Insect nicotinic acetylcholine receptor: conserved neonicotinoid specificity of [(3)H]imidacloprid binding site. |
| AID1104176 | Synergistic ratio of LC50 for adult female Bemisia tabaci B-biotype NJ-Imi (sweet potato whitefly) (G30)to LC50 for adult female Bemisia tabaci B-biotype NJ in presence of 100 mg/L esterase inhibitor, DEF | 2009 | Pest management science, Nov, Volume: 65, Issue:11 | Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. |
| AID1081824 | Resistance index, ratio of LC50 for rothamsted-resistant Bemisia tabaci Q-biotype R-CHLORAKA (sweet potato whitefly) to LC50 for Bemisia tabaci SUD-S | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1104215 | Inhibition of Ceutorhynchus obstrictus development in canola pods of plant developed from compound treated seeds assessed as decrease in number of exit holes formed by larvae at 0.23 kg AI per 45.36 kg seeds | 2009 | Pest management science, Dec, Volume: 65, Issue:12 | Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid. |
| AID1103845 | Resistance ratio of LC50 for Nilaparvata lugens (brown planthopper) F1 progeny to LC50 for imidacloprid-susceptible brown planthopper | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Inheritance mode and realized heritability of resistance to imidacloprid in the brown planthopper, Nilaparvata lugens (Stål) (Homoptera: Delphacidae). |
| AID1104725 | Resistance ratio of LC50 for Bemisia tabaci biotype-B B4 (sweet potato whitefly) to LC50 for Bemisia tabaci LABS | 2010 | Pest management science, Nov, Volume: 66, Issue:11 | Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae). |
| AID145520 | Binding affinity for nAChR with [3H]-nicotine in rat alpha4 beta2 membranes | 2000 | Journal of medicinal chemistry, Dec-28, Volume: 43, Issue:26 | 5-Azidoimidacloprid and an acyclic analogue as candidate photoaffinity probes for mammalian and insect nicotinic acetylcholine receptors. |
| AID1111972 | Insecticidal activity against cotton aphid Aphis gossypii F9 (cotton aphid) in cotton leaves assessed as mortality measured after 48 hr by dipping method | 2011 | Pest management science, Dec, Volume: 67, Issue:12 | Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii. |
| AID1081830 | Insecticidal activity against Bemisia tabaci SUD-S (sweet potato whitefly) by leaf disk bioassay | 2011 | Journal of agricultural and food chemistry, Apr-13, Volume: 59, Issue:7 | Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests. |
| AID1103898 | Toxicity against Metaseiulus occidentalis adults in bean leaf disk infested with two-spotted spider mites assessed as corrected mortality at 0.1600/2 g AI/L treated using worst-case laboratory exposure procedure measured after 72 hr | 2009 | Pest management science, Jun, Volume: 65, Issue:6 | Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1159550 | Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening | 2015 | Nature cell biology, Nov, Volume: 17, Issue:11 | 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 32 (1.43) | 18.2507 |
| 2000's | 503 (22.42) | 29.6817 |
| 2010's | 1168 (52.05) | 24.3611 |
| 2020's | 541 (24.11) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.
| This Compound (55.54) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Trials | 0 (0.00%) | 5.53% |
| Trials | 102 (4.59%) | 5.53% |
| Reviews | 1 (1.41%) | 6.00% |
| Reviews | 1 (16.67%) | 6.00% |
| Reviews | 28 (1.26%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Case Studies | 0 (0.00%) | 4.05% |
| Case Studies | 41 (1.84%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Observational | 0 (0.00%) | 0.25% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 70 (98.59%) | 84.16% |
| Other | 5 (83.33%) | 84.16% |
| Other | 2,052 (92.31%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| ADVANTAGE Prosthetic Heart Valve Long Term Follow Up [NCT01264484] | 212 participants (Actual) | Observational | 2010-12-31 | Terminated(stopped due to The primary objective was considered sufficient for follow-up.) | |||
| Zimmer Biomet Patient Outcome and Experience After Chest Wall Repair With RibFix Advantage™ [NCT05179005] | 50 participants (Anticipated) | Observational | 2023-04-20 | Recruiting | |||
| Hepatic Glucose Metabolism Measured by FDG PET/CT in Patients With Liver Disease and Healthy Subjects [NCT01369979] | 13 participants (Actual) | Observational | 2011-05-31 | Completed | |||
| Longitudinal Tracking and Intervention Platform for Medicare Advantage Patients: A Prospective RCT [NCT04658160] | 1,000 participants (Anticipated) | Interventional | 2024-12-31 | Not yet recruiting | |||
| Implantation of the HiRes90K™ Advantage Cochlear Implant With HiFocus™ Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults With Partial Deafness [NCT02189798] | 40 participants (Actual) | Interventional | 2014-10-21 | Terminated(stopped due to Thirty-six subjects wore the EAS processor for as long as 84 months without any significant safety issues. Sufficient data gained to support EAS technology development for safe use in subjects with residual low-frequency acoustic hearing sensitivity.) | |||
| Comparison of N-of-1 Trials of Light Therapy for Depressive Symptoms in Cancer Survivors [NCT03167372] | 15 participants (Actual) | Interventional | 2017-09-06 | Completed | |||
| A Prospective, Single-Arm, Post Market Clinical Study to Evaluate a Mid-Urethral Vaginal Tape Procedure With a Pre-Pubic Delivery Approach, for the Treatment of Stress Urinary Incontinence [NCT00688298] | 100 participants (Actual) | Interventional | 2004-05-31 | Completed | |||
| Effectiveness and Costs of Albuterol Delivered by MDI With Spacer Versus Nebulizer in Children Hospitalized With Moderate and Severe Asthma Exacerbations [NCT00623688] | 11 participants (Actual) | Interventional | 2008-02-29 | Completed | |||
| Functional Outcome and Complications After Global Unite ® Prostheses in Osteoarthritis and Displaced Fractures of the Proximal Humerus. [NCT03097406] | 88 participants (Anticipated) | Observational | 2017-01-01 | Active, not recruiting | |||
| Clinical Validation of Suntech Advantage MX With Suntech Neonate and Children Cuff Line Against Invasive Intra-arterial Reference According to the ANSI/AAMI/ISO 810602-2019 Protocol for Neonates, Infants, Children [NCT06172829] | 18 participants (Anticipated) | Observational | 2023-11-07 | Recruiting | |||
| Employing a Single Step Media Can Improve the Clinical Outcomes in Those Patient Who Usually Show an High Cycle Cancellation Rate? [NCT02575924] | Phase 1 | 24 participants (Anticipated) | Interventional | 2015-06-30 | Recruiting | ||
| Clinical Effectiveness of Quiropodiatry and Orthesis on Heel and Plantar Pain: Randomized Control Trial [NCT00888394] | Phase 4 | 312 participants (Actual) | Interventional | 2009-09-30 | Completed | ||
| Minimal Invasive Approach for Surgical Repair of Rib Fractures With a Novel Intrathoracic Device. Case Series [NCT04163224] | 0 participants (Actual) | Observational | 2020-04-01 | Withdrawn(stopped due to Sponsor strategy change) | |||
| Addis Ababa University [NCT04521517] | 346 participants (Anticipated) | Interventional | 2020-09-15 | Not yet recruiting | |||
| Evaluation of Hearing Preservation in Adults With Partial Low-Frequency Hearing Implanted With the HiFocus™ Mid-Scala Electrode [NCT01959152] | 1 participants (Actual) | Interventional | 2013-10-31 | Terminated | |||
| Dynamic Vision Testing and Concussion Management Dream Team 65 [NCT05326555] | 100 participants (Anticipated) | Observational | 2021-10-01 | Recruiting | |||
| A Randomized Study of the Treatment of Urodynamic Stress Incontinence: the Tension Free Vaginal Tape (TVT) Versus the Miniarc Sling. [NCT00843908] | 70 participants (Anticipated) | Interventional | 2008-02-29 | Completed | |||
| Clinical Evaluation of the Effectiveness of Different Methods in Reducing Pain During Debonding of Orthodontic Fixed Appliance: a Randomized Clinical Trial [NCT05904587] | 128 participants (Anticipated) | Interventional | 2023-03-19 | Recruiting | |||
| Coherence Training for Military Personnel [NCT01599598] | 192 participants (Actual) | Interventional | 2012-04-30 | Completed | |||
| Phase 1 Safety Evaluation of Advantage Anti-Caries Varnish [NCT02645617] | Phase 1 | 12 participants (Actual) | Interventional | 2016-03-30 | Completed | ||
| Dynamic Vision Testing and Concussion Management [NCT04837066] | 100 participants (Anticipated) | Observational | 2021-08-31 | Recruiting | |||
| SASS: Randomized Trial of Single-incision Versus Retropubic Mid-Urethral Sling (Solyx) for Concomitant Management of Stress Urinary Incontinence During Minimally Invasive Sacrocolpopexy [NCT04586166] | 180 participants (Anticipated) | Interventional | 2020-12-23 | Recruiting | |||
| Assessment of the Effect of B. Braun Peripheral Advantage Program on Complications, Indwell Time and First Stick Success of PIVC Therapy [NCT04048863] | 44 participants (Actual) | Interventional | 2020-01-24 | Terminated(stopped due to This study was terminated due to recruitment futility resulting from the significant impact of the COVID-19 pandemic to our intended study population and facility personnel.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||