Galectin-8

A galectin-8 that is encoded in the genome of human. [PRO:DNx, UniProtKB:O00214]

Gal-8;
Po66 carbohydrate-binding protein;
Po66-CBP;
Prostate carcinoma tumor antigen 1;
PCTA-1

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
lactose	Homo sapiens (human)	Kd	63.6400	3	3
methyl alpha-d-galactopyranoside	Homo sapiens (human)	Kd	6,300.0000	1	1
methyl beta-galactoside	Homo sapiens (human)	Kd	12,785.7143	7	7
thiodigalactoside	Homo sapiens (human)	Kd	61.0000	4	4
methyl lactoside	Homo sapiens (human)	Kd	62.0000	1	1
n-acetyllactosamine	Homo sapiens (human)	Kd	1,000.0000	1	1
galactal	Homo sapiens (human)	Kd	2,700.0000	2	2
N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucose	Homo sapiens (human)	Kd	2.3000	1	1

This protein enables 3 target(s):

Target	Category	Definition
integrin binding	molecular function	Binding to an integrin. [GOC:ceb]
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
carbohydrate binding	molecular function	Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. [GOC:mah]

This protein is located in 5 target(s):

Target	Category	Definition
extracellular space	cellular component	That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684]
cytoplasm	cellular component	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
cytosol	cellular component	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
membrane	cellular component	A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
cytoplasmic vesicle	cellular component	A vesicle found in the cytoplasm of a cell. [GOC:ai, GOC:mah, GOC:vesicles]

This protein is active in 1 target(s):

Target	Category	Definition
cytoplasm	cellular component	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]

This protein is involved in 3 target(s):

Target	Category	Definition
cellular response to virus	biological process	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. [GOC:dos]
xenophagy	biological process	The selective degradation of intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) by macroautophagy. [GOC:autophagy, GOC:pad, GOC:PARL, PMID:19802565, PMID:20159618, PMID:25497060]
lymphatic endothelial cell migration	biological process	The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel. [GO_REF:0000091, GOC:TermGenie, PMID:25745057]