A galectin-8 that is encoded in the genome of human. [PRO:DNx, UniProtKB:O00214]
Gal-8;
Po66 carbohydrate-binding protein;
Po66-CBP;
Prostate carcinoma tumor antigen 1;
PCTA-1
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 5 (55.56) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| lactose | Homo sapiens (human) | Kd | 63.6400 | 3 | 3 |
| methyl alpha-d-galactopyranoside | Homo sapiens (human) | Kd | 6,300.0000 | 1 | 1 |
| methyl beta-galactoside | Homo sapiens (human) | Kd | 12,785.7143 | 7 | 7 |
| thiodigalactoside | Homo sapiens (human) | Kd | 61.0000 | 4 | 4 |
| methyl lactoside | Homo sapiens (human) | Kd | 62.0000 | 1 | 1 |
| n-acetyllactosamine | Homo sapiens (human) | Kd | 1,000.0000 | 1 | 1 |
| galactal | Homo sapiens (human) | Kd | 2,700.0000 | 2 | 2 |
| N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucose | Homo sapiens (human) | Kd | 2.3000 | 1 | 1 |
This protein enables 3 target(s):
| Target | Category | Definition |
|---|---|---|
| integrin binding | molecular function | Binding to an integrin. [GOC:ceb] |
| protein binding | molecular function | Binding to a protein. [GOC:go_curators] |
| carbohydrate binding | molecular function | Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. [GOC:mah] |
This protein is located in 5 target(s):
| Target | Category | Definition |
|---|---|---|
| extracellular space | cellular component | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684] |
| cytoplasm | cellular component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
| cytosol | cellular component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
| membrane | cellular component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
| cytoplasmic vesicle | cellular component | A vesicle found in the cytoplasm of a cell. [GOC:ai, GOC:mah, GOC:vesicles] |
This protein is active in 1 target(s):
| Target | Category | Definition |
|---|---|---|
| cytoplasm | cellular component | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684] |
This protein is involved in 3 target(s):
| Target | Category | Definition |
|---|---|---|
| cellular response to virus | biological process | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. [GOC:dos] |
| xenophagy | biological process | The selective degradation of intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) by macroautophagy. [GOC:autophagy, GOC:pad, GOC:PARL, PMID:19802565, PMID:20159618, PMID:25497060] |
| lymphatic endothelial cell migration | biological process | The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel. [GO_REF:0000091, GOC:TermGenie, PMID:25745057] |