Proteins > DNA polymerase catalytic subunit
Page last updated: 2024-08-07 19:27:22
DNA polymerase catalytic subunit
[no definition available]
Synonyms
EC 2.7.7.7
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (4)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| foscarnet | Human herpesvirus 5 strain AD169 | IC50 | 2.5000 | 2 | 2 |
| zidovudine triphosphate | Human herpesvirus 5 strain AD169 | IC50 | 22.1000 | 2 | 2 |
| aphidicolin | Human herpesvirus 5 strain AD169 | IC50 | 0.4435 | 2 | 2 |
| pnu183792 | Human herpesvirus 5 strain AD169 | IC50 | 0.7000 | 1 | 1 |
2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.Bioorganic & medicinal chemistry letters, , Jun-15, Volume: 17, Issue:12, 2007
4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases.Journal of medicinal chemistry, , Sep-08, Volume: 48, Issue:18, 2005
2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.Bioorganic & medicinal chemistry letters, , Jun-15, Volume: 17, Issue:12, 2007
4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases.Journal of medicinal chemistry, , Sep-08, Volume: 48, Issue:18, 2005
2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.Bioorganic & medicinal chemistry letters, , Jun-15, Volume: 17, Issue:12, 2007
4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases.Journal of medicinal chemistry, , Sep-08, Volume: 48, Issue:18, 2005