Page last updated: 2024-11-06
6-hydroxychrysene
Description
6-hydroxychrysene is a polycyclic aromatic hydrocarbon (PAH) that has been identified as a potential environmental contaminant. It is a known mutagen and has been shown to be carcinogenic in animal studies. The compound has been detected in various environmental samples, including air, soil, and water, suggesting its widespread presence. 6-hydroxychrysene is of interest to researchers due to its potential health effects and its role in understanding the environmental fate and transport of PAHs. The synthesis of 6-hydroxychrysene typically involves a multi-step process, such as the reaction of chrysene with a hydroxylating agent. Studies on 6-hydroxychrysene focus on its environmental fate and transport, its biological activity, and its potential health risks to humans and other organisms.'
chrysen-6-ol : A hydroxychrysene that is chrysene in which the hydrogen at position 6 has been replaced by a hydroxy group. It is a metabolite of the polycyclic aromatic hydrocarbon chrysene. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 37766 |
| CHEBI ID | 132407 |
| SCHEMBL ID | 8288093 |
| MeSH ID | M0231031 |
Synonyms (17)
| Synonym |
|---|
| brn 1970026 |
| 6-chrysenol |
| ccris 2031 |
| 6-hydroxychrysene |
| 37515-51-8 |
| 6-hydroxy-chrysene |
| CHEBI:132407 |
| chrysen-6-ol |
| unii-9crj4nm6hv |
| 9crj4nm6hv , |
| SCHEMBL8288093 |
| VXFDOYXVHRYCGS-UHFFFAOYSA-N |
| j356.071f , |
| DTXSID6038324 |
| 2-benzothiazolamine,6-chloro-4-methyl-(9ci) |
| FT-0775055 |
| Q27225567 |
Roles (1)
| Role | Description |
|---|
| xenobiotic metabolite | Any metabolite produced by metabolism of a xenobiotic compound. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (1)
| Class | Description |
|---|
| hydroxychrysene | A member of the class of phenols that has a chrysene skeleton which is substituted by one of more hydroxy groups. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (7)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.76
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.76 (24.57) | | Research Supply Index | 2.20 (2.92) | | Research Growth Index | 4.96 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |