A cytochrome P450 11B that is a translation product of the Cyp11b2 gene in rat. [PRO:DAN]
Aldosterone synthase;
ALDOS;
Aldosterone-synthesizing enzyme;
CYPXIB2;
Corticosterone 18-monooxygenase, CYP11B2;
1.14.15.5;
Cytochrome P-450Aldo;
Cytochrome P-450C18;
Cytochrome P450-Aldo-1;
Steroid 11-beta-hydroxylase
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| aminoglutethimide | Rattus norvegicus (Norway rat) | IC50 | 70.0000 | 2 | 3 |
| fadrozole | Rattus norvegicus (Norway rat) | IC50 | 0.6000 | 1 | 1 |
| vorozole | Rattus norvegicus (Norway rat) | IC50 | 12.0000 | 1 | 1 |
| osilodrostat | Rattus norvegicus (Norway rat) | IC50 | 0.1110 | 1 | 1 |