leucrose profile

leucrose: RN given refers to all (D)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

leucrose : A glycosylfructose consisting of an alpha-D-glucopyranosyl residue joined to D-fructopyranose via a (1->5)-linkage. An isomer of sucrose. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	165577
SCHEMBL ID	3832014
MeSH ID	M0168140

Synonym
leucrose
4B42CA92-416A-4C2C-BAAA-D31AD7F77B1F
d-glucopyranosyl-alpha(1-5)-d-fructopyranose
unii-yac4299isi
d-fructose, 5-o-alpha-d-glucopyranosyl-
yac4299isi ,
d-fructose, 5-o-.alpha.-d-glucopyranosyl-
470-16-6
5-o-.alpha.-d-glucopyranosyl-d-fructose
SCHEMBL3832014
n2-[n2-(1-l-threonyl-l-prolyl)-l-arginyl]-l-lysine diacetate salt
W-203595
(3s,4s,5r)-1,3,4,6-tetrahydroxy-5-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-hexan-2-one
(3s,4s,5r)-5-[(2r,3r,4s,5s,6r)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1,3,4,6-tetrakis(oxidanyl)hexan-2-one
Q3237106
DXALOGXSFLZLLN-WTZPKTTFSA-N
DTXSID40992132
5-o-hexopyranosylhex-2-ulose
(3s,4s,5r)-1,3,4,6-tetrahydroxy-5-(((2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)oxy)hexan-2-one
F81529
AKOS040752512

Excerpt	Reference	Relevance
"Leucrose is a novel noncariogenic disaccharide and thus represents a highly promising sugar substitute for caries prevention."	( Cariological assessment of leucrose [D-glucopyranosyl-alpha(1----5)-D-fructopyranose] as a sugar substitute. Imfeld, T; Siebert, G; Ziesenitz, SC, 1989)	1.3

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	3 (13.04)	18.7374
1990's	8 (34.78)	18.2507
2000's	10 (43.48)	29.6817
2010's	2 (8.70)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (4.17%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	23 (95.83%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
lactic acid Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed). 2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.	2	1	2-hydroxy monocarboxylic acid	algal metabolite; Daphnia magna metabolite
saccharin Saccharin: Flavoring agent and non-nutritive sweetener.. saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.	1.97	1	1,2-benzisothiazole; N-sulfonylcarboxamide	environmental contaminant; sweetening agent; xenobiotic
sorbitol D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).	1.97	1	glucitol	cathartic; Escherichia coli metabolite; food humectant; human metabolite; laxative; metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite; sweetening agent
sucrose Saccharum: A plant genus of the family POACEAE widely cultivated in the tropics for the sweet cane that is processed into sugar.	4.82	10	glycosyl glycoside	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; osmolyte; Saccharomyces cerevisiae metabolite; sweetening agent
trehalose alpha,alpha-trehalose : A trehalose in which both glucose residues have alpha-configuration at the anomeric carbon.	2.42	2	trehalose	Escherichia coli metabolite; geroprotector; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
isomaltose [no description available]	4.72	9
hydrofluoric acid Hydrofluoric Acid: Hydrofluoric acid. A solution of hydrogen fluoride in water. It is a colorless fuming liquid which can cause painful burns.. hydrogen fluoride : A diatomic molecule containing covalently bonded hydrogen and fluorine atoms.. organofluorine compound : An organofluorine compound is a compound containing at least one carbon-fluorine bond.	2.38	2	hydrogen halide; mononuclear parent hydride	NMR chemical shift reference compound
2,2-bis(bromomethyl)-1,3-propanediol 2,2-bis(bromomethyl)-1,3-propanediol: structure given in first source	2.43	2	primary alcohol
isomaltulose 6-O-alpha-D-glucopyranosyl-D-fructofuranose : A glycosylfructose that is D-fructofuranose attached to a alpha-D-glucopyranosyl unit at position 6 via a glycosidic linkage. It is found in honey and sugarcane.	4.62	8	glycosylfructose	animal metabolite; plant metabolite; sweetening agent
glycosides [no description available]	2.04	1
D-fructopyranose [no description available]	3.25	6	cyclic hemiketal; D-fructose; fructopyranose	sweetening agent
kojibiose [no description available]	2.04	1
aluminum Aluminum: A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.	2.01	1	boron group element atom; elemental aluminium; metal atom
turanose turanose : A glycosylfructose isolated from Daphnia magna.	4.21	5	glycosylfructose	Daphnia magna metabolite
silicon Silicon: A trace element that constitutes about 27.6% of the earth's crust in the form of SILICON DIOXIDE. It does not occur free in nature. Silicon has the atomic symbol Si, atomic number 14, and atomic weight [28.084; 28.086].	2.01	1	carbon group element atom; metalloid atom; nonmetal atom
acebutolol alpha-D-glucosyl-(1->4)-alpha-D-mannose : An alpha-D-glucosyl-(1->4)-D-mannopyranose in which the anomeric hydroxy group has alpha configuration.	2.93	4	alpha-D-glucosyl-(1->4)-D-mannopyranose
lactulose Lactulose: A synthetic disaccharide used in the treatment of constipation and hepatic encephalopathy. It has also been used in the diagnosis of gastrointestinal disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p887). lactulose : A synthetic galactosylfructose disaccharide used in the treatment of constipation and hepatic encephalopathy.	2.68	3
trehalulose trehalulose: alpha-(1-1) linked disaccharide. trehalulose : A glycosyl glycoside prepared from alpha-D-glucopyranosyl and beta-D-fructofuranose residues.	3.56	2

Condition	Relationship Strength	Studies
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	2.41	2
Caries, Dental [description not available]	2.39	2
Dental Caries Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.	2.39	2
Dental Plaque A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.	1.97	1
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	1.97	1

leucrose

Description

Cross-References

Synonyms (21)

Research Excerpts

Overview

Research

Studies (23)

Market Indicators

Research Demand Index: 28.61

Study Types