Page last updated: 2024-08-07 22:37:03
RNA-directed RNA polymerase catalytic subunit
An RNA-directed RNA polymerase catalytic subunit (Influenza A virus) that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934. [PMID:18660801, PMID:19461581, PRO:CNA, UniProtKB:P03431]
Synonyms
EC 2.7.7.48;
Polymerase basic protein 1;
PB1;
RNA-directed RNA polymerase subunit P1
Research
Bioassay Publications (3)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| N-(7-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)benzamide | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | IC50 | 200.0000 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| ribavirin | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | EC50 | 21.2667 | 3 | 3 |