A ceramide glucosyltransferase that is encoded in the genome of mouse. [OMA:O88693, PRO:DNx]
EC 2.4.1.80;
GLCT-1;
Glucosylceramide synthase;
GCS;
UDP-glucose ceramide glucosyltransferase;
UDP-glucose:N-acylsphingosine D-glucosyltransferase
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| miglustat | Mus musculus (house mouse) | IC50 | 40.9667 | 3 | 3 |
| fagomine | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| n-nonyl-1-deoxynojirimycin | Mus musculus (house mouse) | IC50 | 4.0000 | 1 | 1 |
| n-(5-adamantane-1-yl-methoxy-pentyl)deoxynojirimycin | Mus musculus (house mouse) | IC50 | 0.2000 | 2 | 2 |
| ogt2378 | Mus musculus (house mouse) | IC50 | 15.0000 | 1 | 1 |
| 3-epi-fagomine | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |