Polyunsaturated fatty acid lipoxygenase ALOX15B

A polyunsaturated fatty acid lipoxygenase ALOX15B that is encoded in the genome of human. [PRO:DNx, UniProtKB:O15296]

Synonyms

15-lipoxygenase 2;
15-LOX-2;
Arachidonate 15-lipoxygenase B;
15-LOX-B;
1.13.11.33;
Arachidonate 15-lipoxygenase type II;
Linoleate 13-lipoxygenase 15-LOb;
1.13.11.-

Research

Bioassay Publications (9)

Timeframe	Studies on this Protein(%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (11.11)	29.6817
2010's	7 (77.78)	24.3611
2020's	1 (11.11)	2.80

Compounds (939)

Drugs with Potency Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)
catechol	Homo sapiens (human)	Potency	12.5893	1
chlordecone	Homo sapiens (human)	Potency	31.6228	1
spermidine	Homo sapiens (human)	Potency	10.0635	1
spermine	Homo sapiens (human)	Potency	15.7142	1
2,4-methanoglutamate	Homo sapiens (human)	Potency	39.8107	1
1-(3-chlorophenyl)piperazine	Homo sapiens (human)	Potency	12.5893	1
2-aminoethoxydiphenyl borate	Homo sapiens (human)	Potency	19.9526	1
p-chloromercuribenzoic acid	Homo sapiens (human)	Potency	3.1623	1
5-(n,n-hexamethylene)amiloride	Homo sapiens (human)	Potency	15.8489	1
ethylisopropylamiloride	Homo sapiens (human)	Potency	15.8489	1
5-(nonyloxy)tryptamine	Homo sapiens (human)	Potency	12.5893	1
6-hydroxymelatonin	Homo sapiens (human)	Potency	12.5893	1
6-nitroso-1,2-benzopyrone	Homo sapiens (human)	Potency	15.8489	1
7,8-dihydroxyflavone	Homo sapiens (human)	Potency	15.8489	1
tacrine	Homo sapiens (human)	Potency	3.1623	1
N-(2-aminoethyl)-5-chloro-1-naphthalenesulfonamide	Homo sapiens (human)	Potency	15.8489	1
rtki cpd	Homo sapiens (human)	Potency	15.8489	1
tyrphostin a23	Homo sapiens (human)	Potency	12.5893	1
tyrphostin 25	Homo sapiens (human)	Potency	5.0119	1
amiodarone	Homo sapiens (human)	Potency	7.9433	1
amitriptyline	Homo sapiens (human)	Potency	20.4839	1
amoxapine	Homo sapiens (human)	Potency	19.9526	1
astemizole	Homo sapiens (human)	Potency	5.7457	1
aurintricarboxylic acid	Homo sapiens (human)	Potency	13.9480	1
benzethonium	Homo sapiens (human)	Potency	12.5893	1
bifemelane	Homo sapiens (human)	Potency	10.0000	1
bisbenzimidazole	Homo sapiens (human)	Potency	3.9811	1
bithionol	Homo sapiens (human)	Potency	5.0119	1
bromperidol	Homo sapiens (human)	Potency	12.5893	1
bu 224	Homo sapiens (human)	Potency	25.1189	1
bufexamac	Homo sapiens (human)	Potency	9.5056	1
butacaine	Homo sapiens (human)	Potency	19.9526	1
candesartan cilexetil	Homo sapiens (human)	Potency	25.1189	1
carbetapentane	Homo sapiens (human)	Potency	10.0000	1
carbonyl cyanide m-chlorophenyl hydrazone	Homo sapiens (human)	Potency	19.9526	1
cgs 12066	Homo sapiens (human)	Potency	17.5594	1
chelerythrine	Homo sapiens (human)	Potency	14.2191	1
chloroxine	Homo sapiens (human)	Potency	25.1189	1
chlorpromazine	Homo sapiens (human)	Potency	11.2947	1
clemizole	Homo sapiens (human)	Potency	4.4965	1
clobenpropit	Homo sapiens (human)	Potency	3.9811	1
clomipramine	Homo sapiens (human)	Potency	8.8568	1
clotrimazole	Homo sapiens (human)	Potency	5.5307	1
cyclobenzaprine	Homo sapiens (human)	Potency	18.8541	1
cyproheptadine	Homo sapiens (human)	Potency	11.9420	1
dequalinium	Homo sapiens (human)	Potency	4.1552	1
desipramine	Homo sapiens (human)	Potency	12.5893	1
r 59022	Homo sapiens (human)	Potency	12.5893	1
dibucaine	Homo sapiens (human)	Potency	19.9526	1
dicyclomine	Homo sapiens (human)	Potency	31.6228	1
pentetic acid	Homo sapiens (human)	Potency	4.1524	1
dilazep	Homo sapiens (human)	Potency	17.5594	1
diphenyleneiodonium	Homo sapiens (human)	Potency	15.8489	1
dipyridamole	Homo sapiens (human)	Potency	19.9526	1
disulfiram	Homo sapiens (human)	Potency	8.8861	1
domperidone	Homo sapiens (human)	Potency	2.7830	1
ebselen	Homo sapiens (human)	Potency	0.5661	1
ellipticine	Homo sapiens (human)	Potency	4.4965	1
embelin	Homo sapiens (human)	Potency	31.6228	1
ethoxyquin	Homo sapiens (human)	Potency	11.2947	1
carbonyl cyanide p-trifluoromethoxyphenylhydrazone	Homo sapiens (human)	Potency	15.8489	1
flufenamic acid	Homo sapiens (human)	Potency	31.6228	1
fluorescite	Homo sapiens (human)	Potency	28.1838	1
fluspirilene	Homo sapiens (human)	Potency	12.5893	1
fusaric acid	Homo sapiens (human)	Potency	19.9526	1
gabexate	Homo sapiens (human)	Potency	12.5893	1
vanoxerine	Homo sapiens (human)	Potency	11.2947	1
gbr 12935	Homo sapiens (human)	Potency	15.0654	1
gossypol	Homo sapiens (human)	Potency	6.1867	1
haloperidol	Homo sapiens (human)	Potency	15.8489	1
hexachlorophene	Homo sapiens (human)	Potency	10.0000	1
hexestrol	Homo sapiens (human)	Potency	19.9526	1
beta-thujaplicin	Homo sapiens (human)	Potency	12.5893	1
hypericin	Homo sapiens (human)	Potency	2.5119	1
imetit	Homo sapiens (human)	Potency	15.8489	1
imipramine	Homo sapiens (human)	Potency	7.9433	1
iodoacetamide	Homo sapiens (human)	Potency	39.8107	1
itraconazole	Homo sapiens (human)	Potency	4.4668	1
1-(2-naphthalenyl)-3-[(phenylmethyl)-propan-2-ylamino]-1-propanone	Homo sapiens (human)	Potency	8.8006	1
1-(2-naphthalenyl)-2-propen-1-one	Homo sapiens (human)	Potency	1.9953	1
juglone	Homo sapiens (human)	Potency	3.1623	1
ketotifen	Homo sapiens (human)	Potency	31.6228	1
lansoprazole	Homo sapiens (human)	Potency	25.1189	1
beta-lapachone	Homo sapiens (human)	Potency	39.8107	1
lidoflazine	Homo sapiens (human)	Potency	12.5893	1
loperamide	Homo sapiens (human)	Potency	16.7658	1
loratadine	Homo sapiens (human)	Potency	12.5893	1
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one	Homo sapiens (human)	Potency	25.1189	1
maprotiline	Homo sapiens (human)	Potency	10.3167	1
mefloquine hydrochloride	Homo sapiens (human)	Potency	25.1189	1
methoctramine	Homo sapiens (human)	Potency	3.1623	1
miconazole	Homo sapiens (human)	Potency	6.3096	1
mitoxantrone	Homo sapiens (human)	Potency	7.8758	1
ml 9	Homo sapiens (human)	Potency	10.2663	1
n(1),n(11)-diethylnorspermine	Homo sapiens (human)	Potency	19.9526	1
n(1), n(12)-diethylspermine	Homo sapiens (human)	Potency	15.8489	1
n-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide	Homo sapiens (human)	Potency	5.0119	1
niclosamide	Homo sapiens (human)	Potency	0.1585	1
nifedipine	Homo sapiens (human)	Potency	10.0000	1
masoprocol	Homo sapiens (human)	Potency	1.5849	1
nortriptyline	Homo sapiens (human)	Potency	18.8541	1
5-nitro-2-(3-phenylpropylamino)benzoic acid	Homo sapiens (human)	Potency	24.7028	1
omeprazole	Homo sapiens (human)	Potency	25.1189	1
oxatomide	Homo sapiens (human)	Potency	15.8489	1
oxethazaine	Homo sapiens (human)	Potency	3.9811	1
pd 153035	Homo sapiens (human)	Potency	25.1189	1
pd 169316	Homo sapiens (human)	Potency	31.6228	1
periciazine	Homo sapiens (human)	Potency	15.8489	1
perphenazine	Homo sapiens (human)	Potency	10.8631	1
phloretin	Homo sapiens (human)	Potency	12.5893	1
phosalone	Homo sapiens (human)	Potency	19.9526	1
phthalylsulfathiazole	Homo sapiens (human)	Potency	15.8489	1
prazosin	Homo sapiens (human)	Potency	25.1189	1
proadifen	Homo sapiens (human)	Potency	11.2947	1
prochlorperazine	Homo sapiens (human)	Potency	15.8489	1
protoporphyrin ix	Homo sapiens (human)	Potency	17.9008	1
protriptyline	Homo sapiens (human)	Potency	16.2710	1
1,2,5,8-tetrahydroxy anthraquinone	Homo sapiens (human)	Potency	0.6310	1
hydrochlorothiazide	Homo sapiens (human)	Potency	7.9433	1
ritanserin	Homo sapiens (human)	Potency	15.8489	1
aurin	Homo sapiens (human)	Potency	31.6228	1
sanguinarine	Homo sapiens (human)	Potency	3.9811	1
sb 202190	Homo sapiens (human)	Potency	7.9433	1
scriptaid	Homo sapiens (human)	Potency	31.6228	1
spiperone	Homo sapiens (human)	Potency	8.9716	1
sulfadimethoxine	Homo sapiens (human)	Potency	31.6228	1
sulfinpyrazone	Homo sapiens (human)	Potency	8.2852	1
2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]-1-propanol	Homo sapiens (human)	Potency	3.9811	1
tinoridine	Homo sapiens (human)	Potency	14.1254	1
trifluoperazine	Homo sapiens (human)	Potency	12.5893	1
trifluperidol	Homo sapiens (human)	Potency	15.8489	1
triflupromazine	Homo sapiens (human)	Potency	8.1548	1
troglitazone	Homo sapiens (human)	Potency	10.0000	1
urapidil	Homo sapiens (human)	Potency	7.9433	1
6,18,30-trimethyl-3,9,12,15,21,24,27,33,36-nona(propan-2-yl)-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone	Homo sapiens (human)	Potency	39.8107	1
w 7	Homo sapiens (human)	Potency	11.2947	1
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole	Homo sapiens (human)	Potency	25.1189	1
promazine hydrochloride	Homo sapiens (human)	Potency	25.1189	1
apomorphine	Homo sapiens (human)	Potency	0.5012	1
promethazine hydrochloride	Homo sapiens (human)	Potency	31.6228	1
edetic acid	Homo sapiens (human)	Potency	3.5481	1
chlorpromazine hydrochloride	Homo sapiens (human)	Potency	15.8489	1
alizarin	Homo sapiens (human)	Potency	15.8489	1
n,n'-diphenyl-4-phenylenediamine	Homo sapiens (human)	Potency	12.5893	1
azoviolet	Homo sapiens (human)	Potency	15.8489	1
iodoform	Homo sapiens (human)	Potency	31.6228	1
tetrabromobisphenol a	Homo sapiens (human)	Potency	20.4839	1
cyclizine	Homo sapiens (human)	Potency	7.9433	1
dimethisoquin	Homo sapiens (human)	Potency	12.5893	1
pseudoephedrine	Homo sapiens (human)	Potency	0.6310	1
phenothiazine	Homo sapiens (human)	Potency	5.0119	1
thiohexam	Homo sapiens (human)	Potency	35.4813	1
fentichlor	Homo sapiens (human)	Potency	15.8489	1
1,3-ditolylguanidine	Homo sapiens (human)	Potency	2.5119	1
p-tert-butyl catechol	Homo sapiens (human)	Potency	5.0119	1
dimethyl-4-phenylenediamine	Homo sapiens (human)	Potency	12.5893	1
4-aminodiphenylamine	Homo sapiens (human)	Potency	2.5119	1
n-isopropyl-n-phenyl-4-phenylenediamine	Homo sapiens (human)	Potency	1.0000	1
n-oxydiethylene-2-benzothiazole sulfenamide	Homo sapiens (human)	Potency	19.9526	1
imipramine hydrochloride	Homo sapiens (human)	Potency	19.9526	1
n(1)-acetylphenylhydrazine	Homo sapiens (human)	Potency	19.9526	1
chloranil	Homo sapiens (human)	Potency	12.5893	1
dianisidine	Homo sapiens (human)	Potency	19.9526	1
2-tolidine	Homo sapiens (human)	Potency	15.8489	1
clorophene	Homo sapiens (human)	Potency	15.8489	1
dibenzothiazyl disulfide	Homo sapiens (human)	Potency	10.0000	1
2-amino-5-nitrothiazole	Homo sapiens (human)	Potency	25.1189	1
suramin sodium	Homo sapiens (human)	Potency	3.1623	1
3-amino-9-ethylcarbazole	Homo sapiens (human)	Potency	15.8489	1
tetrracaine hydrochloride	Homo sapiens (human)	Potency	12.5893	1
ziram	Homo sapiens (human)	Potency	10.0000	1
pentamidine isethionate	Homo sapiens (human)	Potency	12.5893	1
norchlorcyclizine	Homo sapiens (human)	Potency	15.8489	1
N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine	Homo sapiens (human)	Potency	5.0119	1
lithocholic acid	Homo sapiens (human)	Potency	22.3872	1
rhein	Homo sapiens (human)	Potency	25.1189	1
dihydralazine	Homo sapiens (human)	Potency	39.8107	1
ninhydrin	Homo sapiens (human)	Potency	25.1189	1
hematoxylin	Homo sapiens (human)	Potency	0.3981	1
myristic acid	Homo sapiens (human)	Potency	31.6228	1
gentian violet	Homo sapiens (human)	Potency	39.8107	1
eriodictyol	Homo sapiens (human)	Potency	15.8489	1
3-hydroxyflavone	Homo sapiens (human)	Potency	10.0000	1
2-anthramine	Homo sapiens (human)	Potency	3.9811	1
benzydamine	Homo sapiens (human)	Potency	12.5893	1
n-(1,3-dimethylbutyl)-n'-phenyl-1,4-phenylenediamine	Homo sapiens (human)	Potency	1.5849	1
3-methoxycatechol	Homo sapiens (human)	Potency	1.2589	1
benzopurpurine 4b	Homo sapiens (human)	Potency	3.1623	1
monotributyltin trichloride	Homo sapiens (human)	Potency	7.9433	1
2-amino-4-phenylphenol	Homo sapiens (human)	Potency	12.5893	1
sapropterin	Homo sapiens (human)	Potency	19.9526	1
fluanisone	Homo sapiens (human)	Potency	31.6228	1
diethylcarbamazine citrate	Homo sapiens (human)	Potency	10.0000	1
azaperone	Homo sapiens (human)	Potency	15.8489	1
tetrachloroisophthalonitrile	Homo sapiens (human)	Potency	31.6228	1
pimozide	Homo sapiens (human)	Potency	8.1548	1
benperidol	Homo sapiens (human)	Potency	12.5893	1
1,5-naphthalenediamine	Homo sapiens (human)	Potency	15.8489	1
4-(octyloxy)benzoic acid	Homo sapiens (human)	Potency	3.9811	1
pontamine sky blue	Homo sapiens (human)	Potency	15.8489	1
piperacetazine	Homo sapiens (human)	Potency	12.5893	1
dexpropranolol	Homo sapiens (human)	Potency	12.9244	1
alverine citrate	Homo sapiens (human)	Potency	7.5506	1
c.i. acid red 114, disodium salt	Homo sapiens (human)	Potency	3.1623	1
chloropyramine	Homo sapiens (human)	Potency	15.8489	1
pyrithione zinc	Homo sapiens (human)	Potency	15.8489	1
clemastine	Homo sapiens (human)	Potency	18.8541	1
metergoline	Homo sapiens (human)	Potency	12.9244	1
n-(cyclohexylthio)phthalimide	Homo sapiens (human)	Potency	10.0000	1
daunorubicin	Homo sapiens (human)	Potency	15.1861	1
thymolphthalein	Homo sapiens (human)	Potency	3.1623	1
1-(3-chloro-5-benzo[b][1]benzoxepinyl)-4-methylpiperazine	Homo sapiens (human)	Potency	12.5893	1
2-n-octyl-4-isothiazolin-3-one	Homo sapiens (human)	Potency	2.5119	1
carbidopa	Homo sapiens (human)	Potency	22.3872	1
hc blue no. 2	Homo sapiens (human)	Potency	19.9526	1
propafenone hydrochloride	Homo sapiens (human)	Potency	15.8489	1
ciclopirox olamine	Homo sapiens (human)	Potency	9.5056	1
diltiazem	Homo sapiens (human)	Potency	12.5893	1
nicardipine hydrochloride	Homo sapiens (human)	Potency	12.5893	1
3,3',5,5'-tetramethylbenzidine	Homo sapiens (human)	Potency	19.9526	1
propiconazole	Homo sapiens (human)	Potency	31.6228	1
mitoxantrone hydrochloride	Homo sapiens (human)	Potency	3.9811	1
flupirtine	Homo sapiens (human)	Potency	12.5893	1
azelastine hydrochloride	Homo sapiens (human)	Potency	12.5893	1
atomoxetine	Homo sapiens (human)	Potency	7.9433	1
raloxifene hydrochloride	Homo sapiens (human)	Potency	10.0000	1
salmeterol xinafoate	Homo sapiens (human)	Potency	19.9526	1
eticlopride	Homo sapiens (human)	Potency	25.1189	1
niguldipine	Homo sapiens (human)	Potency	15.8489	1
mibefradil	Homo sapiens (human)	Potency	2.6141	1
eliprodil	Homo sapiens (human)	Potency	9.5056	1
5-Aminoacenaphthene	Homo sapiens (human)	Potency	15.8489	1
paroxetine hydrochloride	Homo sapiens (human)	Potency	25.1189	1
propranolol hydrochloride	Homo sapiens (human)	Potency	15.8489	1
amodiaquine hydrochloride	Homo sapiens (human)	Potency	12.5893	1
meclizine monohydrochloride	Homo sapiens (human)	Potency	12.5893	1
bts 54 524	Homo sapiens (human)	Potency	10.0000	1
salvin	Homo sapiens (human)	Potency	0.3548	1
sulconazole, mononitrate, (+-)-isomer	Homo sapiens (human)	Potency	1.0000	1
esreboxetine	Homo sapiens (human)	Potency	10.0000	1
cgs 9343b	Homo sapiens (human)	Potency	31.6228	1
trifluoperazine hydrochloride	Homo sapiens (human)	Potency	10.0000	1
siquil	Homo sapiens (human)	Potency	10.0000	1
caramiphen	Homo sapiens (human)	Potency	31.6228	1
fluphenazine hydrochloride	Homo sapiens (human)	Potency	5.0119	1
iodophthalein	Homo sapiens (human)	Potency	8.9125	1
spiramide	Homo sapiens (human)	Potency	5.0119	1
1,2-dithiol-3-thione	Homo sapiens (human)	Potency	19.9526	1
2-aminodiphenylamine	Homo sapiens (human)	Potency	15.8489	1
clomipramine hydrochloride	Homo sapiens (human)	Potency	6.3096	1
prazosin hydrochloride	Homo sapiens (human)	Potency	15.8489	1
miconazole nitrate	Homo sapiens (human)	Potency	3.1623	1
econazole nitrate	Homo sapiens (human)	Potency	0.7943	1
2-chloro-1,4-benzoquinone	Homo sapiens (human)	Potency	11.2202	1
2,2',2''-terpyridine	Homo sapiens (human)	Potency	2.5119	1
2-amino-4-tert-butylphenol	Homo sapiens (human)	Potency	6.3096	1
aminoquinuride	Homo sapiens (human)	Potency	5.0119	1
masoprocol	Homo sapiens (human)	Potency	2.2106	2
loxapine succinate	Homo sapiens (human)	Potency	31.6228	1
maprotiline hydrochloride	Homo sapiens (human)	Potency	11.2947	1
opipramol hydrochloride	Homo sapiens (human)	Potency	12.5893	1
magnolol	Homo sapiens (human)	Potency	31.6228	1
pacein	Homo sapiens (human)	Potency	3.9811	1
methyl fluorone black	Homo sapiens (human)	Potency	12.5893	1
tetrandrine	Homo sapiens (human)	Potency	12.5893	1
5-(n-methyl-n-isobutyl)amiloride	Homo sapiens (human)	Potency	15.8489	1
amperozide	Homo sapiens (human)	Potency	19.9526	1
pramoxine hydrochloride	Homo sapiens (human)	Potency	12.5893	1
1,2,3,4,5,6-hexabromocyclohexane	Homo sapiens (human)	Potency	19.9526	1
8-(4-tolylsulfonylamino)quinoline	Homo sapiens (human)	Potency	12.5893	1
orphenadrine citrate	Homo sapiens (human)	Potency	19.9526	1
carbetapentane citrate	Homo sapiens (human)	Potency	25.1189	1
mephentermine	Homo sapiens (human)	Potency	3.1623	1
prochlorperazine edisylate salt	Homo sapiens (human)	Potency	3.9811	1
sk&f 95282	Homo sapiens (human)	Potency	12.9244	1
thioproperazine mesylate	Homo sapiens (human)	Potency	12.5893	1
lekoptin	Homo sapiens (human)	Potency	14.2191	1
nsc-87877	Homo sapiens (human)	Potency	3.1623	1
azomethine h	Homo sapiens (human)	Potency	7.9433	1
4-hydroxyantipyrine	Homo sapiens (human)	Potency	10.0000	1
4-methoxydalbergione	Homo sapiens (human)	Potency	19.9526	1
diphyllin	Homo sapiens (human)	Potency	12.5893	1
lobeline	Homo sapiens (human)	Potency	35.4813	1
vinpocetine	Homo sapiens (human)	Potency	5.0119	1
7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one	Homo sapiens (human)	Potency	15.8489	1
gr 127935	Homo sapiens (human)	Potency	5.5528	1
fk 888	Homo sapiens (human)	Potency	22.3872	1
lasolvan	Homo sapiens (human)	Potency	12.5893	1
5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1h indole	Homo sapiens (human)	Potency	25.1189	1
tesmilifene	Homo sapiens (human)	Potency	10.0000	1
benzamil	Homo sapiens (human)	Potency	17.9008	1
3',4'-dichlorobenzamil	Homo sapiens (human)	Potency	15.8489	1
1-(carboxymethylthio)tetradecane	Homo sapiens (human)	Potency	31.6228	1
selenocystamine	Homo sapiens (human)	Potency	1.5849	1
zk 93426	Homo sapiens (human)	Potency	35.4813	1
n-(phenylthio)-epsilon-caprolactam	Homo sapiens (human)	Potency	19.9526	1
gr 113808	Homo sapiens (human)	Potency	15.8489	1
l 655240	Homo sapiens (human)	Potency	39.8107	1
profenamine hydrochloride	Homo sapiens (human)	Potency	12.5893	1
2-palmitoylglycerol	Homo sapiens (human)	Potency	15.8489	1
gefitinib	Homo sapiens (human)	Potency	19.9526	1
1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine	Homo sapiens (human)	Potency	31.6228	1
desloratadine	Homo sapiens (human)	Potency	25.1189	1
w 7	Homo sapiens (human)	Potency	15.8489	1
indatraline	Homo sapiens (human)	Potency	12.5893	1
bd 1008	Homo sapiens (human)	Potency	12.5893	1
4-iodo-n-piperidinoethylbenzamide	Homo sapiens (human)	Potency	25.1189	1
gr 55562	Homo sapiens (human)	Potency	10.0000	1
2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazole	Homo sapiens (human)	Potency	3.9811	1
4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine	Homo sapiens (human)	Potency	31.6228	1
l 733060	Homo sapiens (human)	Potency	10.0000	1
l 741742	Homo sapiens (human)	Potency	15.8489	1
l 741626	Homo sapiens (human)	Potency	10.0000	1
bp 554	Homo sapiens (human)	Potency	12.5893	1
bts 54 505	Homo sapiens (human)	Potency	10.0000	1
cd 437	Homo sapiens (human)	Potency	7.9433	1
5,5,7,12,12,14-hexamethyl-1,4,8,11-tetrazacyclotetradecane	Homo sapiens (human)	Potency	7.9433	1
3',4'-dihydroxyflavone	Homo sapiens (human)	Potency	10.0000	1
3,3',4'-trihydroxyflavone	Homo sapiens (human)	Potency	12.5893	1
escitalopram	Homo sapiens (human)	Potency	15.8489	1
8-(methylsulfonylamino)quinoline	Homo sapiens (human)	Potency	15.8489	1
corbadrine	Homo sapiens (human)	Potency	19.9526	1
2-phenyl-1,2-benzisothiazol-3-(2h)-one	Homo sapiens (human)	Potency	1.2589	1
2-[carboxymethyl-[2-(2,6-diethylanilino)-2-oxoethyl]amino]acetic acid	Homo sapiens (human)	Potency	1.9953	1
sb 203580	Homo sapiens (human)	Potency	25.1189	1
chrysene-1,4-dione	Homo sapiens (human)	Potency	2.5119	1
hexestrol	Homo sapiens (human)	Potency	10.0000	1
fr 122047	Homo sapiens (human)	Potency	31.6228	1
benfluorex hydrochloride	Homo sapiens (human)	Potency	3.9811	1
roxindole	Homo sapiens (human)	Potency	25.1189	1
brazilin	Homo sapiens (human)	Potency	1.9953	1
carbamothioic acid S-[2-(2-methoxyanilino)-2-oxoethyl] ester	Homo sapiens (human)	Potency	3.9811	1
nsc 95397	Homo sapiens (human)	Potency	1.9953	1
1-amino-9,10-dioxo-4-(3-sulfamoylanilino)anthracene-2-sulfonic acid	Homo sapiens (human)	Potency	3.1623	1
berbamine	Homo sapiens (human)	Potency	15.8489	1
N-butyl-1H-benzimidazol-2-amine	Homo sapiens (human)	Potency	19.9526	1
hematoxylin	Homo sapiens (human)	Potency	3.7619	1
2-(1-adamantyl)imidazole	Homo sapiens (human)	Potency	25.1189	1
2,5-bis(5-hydroxymethyl-2-thienyl)furan	Homo sapiens (human)	Potency	17.7828	1
gant 61	Homo sapiens (human)	Potency	3.1623	1
amiodarone hydrochloride	Homo sapiens (human)	Potency	15.8489	1
dicyclomine hydrochloride	Homo sapiens (human)	Potency	15.8489	1
nortriptyline hydrochloride	Homo sapiens (human)	Potency	12.5893	1
N-(3-Benzooxazol-2-yl-4-hydroxy-phenyl)-2-p-tolyloxyacetamide	Homo sapiens (human)	Potency	25.1189	1
L-isoprenaline	Homo sapiens (human)	Potency	19.9526	1
arachidonic acid	Homo sapiens (human)	Potency	31.6228	1
resveratrol	Homo sapiens (human)	Potency	19.9526	1
5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol	Homo sapiens (human)	Potency	5.7457	1
gw 3965	Homo sapiens (human)	Potency	31.6228	1
diethylstilbestrol	Homo sapiens (human)	Potency	15.8489	1
ketoconazole	Homo sapiens (human)	Potency	6.3096	1
purvalanol a	Homo sapiens (human)	Potency	1.9953	1
isotetrandrine	Homo sapiens (human)	Potency	10.0000	1
6-methyl-2-[(4-nitrophenyl)methylthio]-1H-benzimidazole	Homo sapiens (human)	Potency	31.6228	1
dipyrone	Homo sapiens (human)	Potency	18.8541	1
4-(4-chloro-2-methylphenoxy)-n-hydroxybutanamide	Homo sapiens (human)	Potency	15.8489	1
bd 1063	Homo sapiens (human)	Potency	15.8489	1
2-[[(6-bromo-1H-benzimidazol-2-yl)thio]methyl]-1-methylbenzimidazole	Homo sapiens (human)	Potency	1.9953	1
4-chloro-N-(4-chloro-2,5-dimethoxyphenyl)-5-dithiazolimine	Homo sapiens (human)	Potency	25.1189	1
1-[4-[4-[(4-methylphenyl)methylamino]phenyl]-1-piperazinyl]ethanone	Homo sapiens (human)	Potency	10.0000	1
2-[3-[3-[3-(1-imidazolyl)propyl]-4-oxo-2-quinazolinyl]propyl]isoindole-1,3-dione	Homo sapiens (human)	Potency	25.1189	1
1-(1-benzimidazolyl)-3-(1-cyclohex-3-enylmethoxy)-2-propanol	Homo sapiens (human)	Potency	25.1189	1
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[[1-(3,4-dimethoxyphenyl)-5-tetrazolyl]thio]acetamide	Homo sapiens (human)	Potency	39.8107	1
N-[4-chloro-2-[(2,4-dimethoxyanilino)-oxomethyl]phenyl]-2-furancarboxamide	Homo sapiens (human)	Potency	31.6228	1
7-[2-hydroxy-3-(2-methylphenoxy)propyl]-3-methyl-8-(propan-2-ylthio)purine-2,6-dione	Homo sapiens (human)	Potency	39.8107	1
2-(1,3-benzodioxol-5-ylamino)-N-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetamide	Homo sapiens (human)	Potency	39.8107	1
5-(4-propylcyclohexyl)-3-(3-pyridinyl)-1,2,4-oxadiazole	Homo sapiens (human)	Potency	31.6228	1
4-[2-[1-(4-methoxyphenyl)sulfonyl-2-benzimidazolyl]ethyl]morpholine	Homo sapiens (human)	Potency	19.9526	1
2-(1-benzimidazolylmethyl)-5-[(4-chlorophenyl)methylthio]-1,3,4-oxadiazole	Homo sapiens (human)	Potency	25.1189	1
N-[1-methyl-5-(4-methylphenyl)-2-imidazolyl]-4-oxo-4-(1-piperidinyl)butanamide	Homo sapiens (human)	Potency	39.8107	1
1-[(7,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-[(1-ethyl-2-pyrrolidinyl)methyl]-3-(2-methoxyphenyl)urea	Homo sapiens (human)	Potency	15.8489	1
N-(1,3-benzodioxol-5-yl)-2-[2-(3-chloro-4-methylanilino)-2-oxoethyl]sulfinylacetamide	Homo sapiens (human)	Potency	19.9526	1
5-(1,3-benzodioxol-5-yl)-1-methyl-2-imidazolamine	Homo sapiens (human)	Potency	25.1189	1
1-[4-[4-[(phenylmethyl)amino]phenyl]-1-piperazinyl]ethanone	Homo sapiens (human)	Potency	15.8489	1
N-[1-(2-methoxyphenyl)-5-benzimidazolyl]benzenesulfonamide	Homo sapiens (human)	Potency	25.1189	1
N-[1-[4-(4-methylphenyl)-2-thiazolyl]-4-piperidinyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamide	Homo sapiens (human)	Potency	39.8107	1
6-chloro-2-[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-piperidinyl]-1H-benzimidazole	Homo sapiens (human)	Potency	19.9526	1
6-amino-4-(2,5-dimethoxyphenyl)-3-methyl-1-(4-methylphenyl)-4H-pyrano[2,3-c]pyrazole-5-carbonitrile	Homo sapiens (human)	Potency	1.9953	1
N4-(2-furanylmethyl)-N2-(3-methylphenyl)-6-(4-morpholinyl)-1,3,5-triazine-2,4-diamine	Homo sapiens (human)	Potency	25.1189	1
1-[3-(dimethylamino)propyl]-1-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-3-(phenylmethyl)urea	Homo sapiens (human)	Potency	19.9526	1
2-[(4-fluorophenoxy)methyl]-5-[3-(1-imidazolyl)propylamino]-4-oxazolecarbonitrile	Homo sapiens (human)	Potency	19.9526	1
N-(5-methoxy-1,3-benzothiazol-2-yl)-3-methylbutanamide	Homo sapiens (human)	Potency	2.5119	1
N-[2-[2-[2-(4-methoxyanilino)-2-oxoethyl]-5-tetrazolyl]phenyl]-2-furancarboxamide	Homo sapiens (human)	Potency	19.9526	1
3-(4-methoxyphenyl)-8-(6-methyl-2-phenyl-4-pyrimidinyl)-8-azabicyclo[3.2.1]octan-3-ol	Homo sapiens (human)	Potency	25.1189	1
1-cyclohexyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-amine	Homo sapiens (human)	Potency	25.1189	1
6,6,7-trimethyl-1-(4-morpholinyl)-3-(phenylmethylthio)-5,8-dihydro-2,7-naphthyridine-4-carbonitrile	Homo sapiens (human)	Potency	3.1623	1
LSM-16947	Homo sapiens (human)	Potency	19.9526	1
5-ethyl-4,6-dimethyl-2-sulfanylidene-1H-pyridine-3-carbonitrile	Homo sapiens (human)	Potency	31.6228	1
3-(4-butyl-3,5-dimethyl-1-pyrazolyl)-5-methyl-[1,2,4]triazino[5,6-b]indole	Homo sapiens (human)	Potency	7.9433	1
5-bromo-3-[[2-(4-cyclohexyl-1-piperazinyl)-1-oxoethyl]amino]-1H-indole-2-carboxylic acid methyl ester	Homo sapiens (human)	Potency	25.1189	1
(1-methyl-2-imidazolyl)-(4-phenylmethoxyphenyl)methanol	Homo sapiens (human)	Potency	19.9526	1
4-chlorobenzoic acid 2-(2-amino-3-cyano-1-pyrrolo[3,2-b]quinoxalinyl)ethyl ester	Homo sapiens (human)	Potency	39.8107	1
2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-(8-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)ethanone	Homo sapiens (human)	Potency	3.1623	1
2-(2-oxo-3H-1,4-benzoxazin-4-yl)acetic acid [2-(3-bromo-4-methoxyphenyl)-2-oxoethyl] ester	Homo sapiens (human)	Potency	6.3096	1
4-[1-(4-hydroxyphenyl)ethenyl]phenol	Homo sapiens (human)	Potency	25.1189	1
2-(2,4-dioxo-3-phenyl-5-thiazolidinyl)-N-phenylacetamide	Homo sapiens (human)	Potency	6.3096	1
2-ethyl-1-[(2-methoxyphenyl)methyl]benzimidazole	Homo sapiens (human)	Potency	15.8489	1
2-(butan-2-ylamino)-N-[4-[5-[[2-(butan-2-ylamino)-1-oxoethyl]amino]-1,3-benzoxazol-2-yl]phenyl]acetamide	Homo sapiens (human)	Potency	12.5893	1
2-[(2-fluorophenoxy)methyl]-5-[3-(1-imidazolyl)propylamino]-4-oxazolecarbonitrile	Homo sapiens (human)	Potency	39.8107	1
5-bromo-3-[[2-(4-methyl-1-piperazinyl)-1-oxoethyl]amino]-2-benzofurancarboxylic acid ethyl ester	Homo sapiens (human)	Potency	15.8489	1
2-[2-[(1-phenyl-4-pyrazolo[3,4-d]pyrimidinyl)amino]ethoxy]ethanol	Homo sapiens (human)	Potency	15.8489	1
1-(3,5-dichlorophenyl)-3-(N-hydroxyanilino)pyrrolidine-2,5-dione	Homo sapiens (human)	Potency	15.8489	1
4-(cyclohexylamino)-2-(3,5-dimethyl-1-pyrazolyl)-5-pyrimidinecarboxylic acid ethyl ester	Homo sapiens (human)	Potency	6.3096	1
1-(3,4-dichlorophenyl)-2-[[4-(2-furanylmethyl)-5-(3-pyridinyl)-1,2,4-triazol-3-yl]thio]ethanone	Homo sapiens (human)	Potency	15.8489	1
3-methyl-N-(1-propyl-3-pyrazolo[3,4-b]quinolinyl)butanamide	Homo sapiens (human)	Potency	39.8107	1
6-[(2,4-dichlorophenoxy)methyl]-3-(2-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole	Homo sapiens (human)	Potency	19.9526	1
4-[4-(1H-benzimidazol-2-ylmethyl)-1-piperazinyl]benzofuro[3,2-d]pyrimidine	Homo sapiens (human)	Potency	15.8489	1
4-(1H-benzimidazol-2-ylmethylthio)-2-methylbenzofuro[3,2-d]pyrimidine	Homo sapiens (human)	Potency	25.1189	1
LSM-26505	Homo sapiens (human)	Potency	25.1189	1
2-[4-[(4-chlorophenyl)methoxy]phenyl]-5-[3-(1-imidazolyl)propylamino]-4-oxazolecarbonitrile	Homo sapiens (human)	Potency	3.1623	1
3-[[2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-oxoethyl]amino]-1H-indole-2-carboxylic acid methyl ester	Homo sapiens (human)	Potency	19.9526	1
3-(3-benzoyl-6-chloro-4,5-dihydroxy-7-benzofuranyl)pentane-2,4-dione	Homo sapiens (human)	Potency	1.0000	1
1-[(4-fluorophenyl)methyl]-3-(2-furanylmethyl)-4-imino-6,6-dimethyl-5,8-dihydropyrano[2,3]thieno[2,4-b]pyrimidin-2-one	Homo sapiens (human)	Potency	31.6228	1
Glyceryl lactopalmitate	Homo sapiens (human)	Potency	31.6228	1
3-[[2-(3,5-dimethyl-1-pyrazolyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl]amino]-1-propanol	Homo sapiens (human)	Potency	3.9811	1
3-(4-methoxyphenyl)-6-[(4-methylphenoxy)methyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole	Homo sapiens (human)	Potency	39.8107	1
N5,N5-dimethyl-2,1,3-benzoxadiazole-4,5-diamine	Homo sapiens (human)	Potency	15.8489	1
7-methyl-3-(3-methylbutylamino)-1-(1-pyrrolidinyl)-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile	Homo sapiens (human)	Potency	7.9433	1
3-[(3aR,6aS)-6'-chloro-5-(4-chlorophenyl)-7'-methyl-2',4,6-trioxo-1-spiro[1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3,3'-1H-indole]yl]propanamide	Homo sapiens (human)	Potency	31.6228	1
7-(3,4-dimethoxyphenyl)-4-methyl-2-[4-(phenylmethyl)-1-piperazinyl]-7,8-dihydro-6H-quinazolin-5-one	Homo sapiens (human)	Potency	15.8489	1
N-[1-methyl-2-[2-(4-phenyl-1-piperazinyl)ethyl]-5-benzimidazolyl]-2-furancarboxamide	Homo sapiens (human)	Potency	12.5893	1
2-methyl-3-phenyl-5-propyl-7-[4-(2-pyridinyl)-1-piperazinyl]pyrazolo[1,5-a]pyrimidine	Homo sapiens (human)	Potency	25.1189	1
(3aR,6aS)-3-(3,4-dimethoxyphenyl)-5-(2,4-dimethylphenyl)-3a,6a-dihydropyrrolo[3,4-d]isoxazole-4,6-dione	Homo sapiens (human)	Potency	12.5893	1
3-(1,3-benzodioxol-5-ylmethyl)-4,10-dihydro-2H-[1,3,5]triazino[1,2-a]benzimidazole	Homo sapiens (human)	Potency	19.9526	1
N2-(4-fluorophenyl)-6-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-1,3,5-triazine-2,4-diamine	Homo sapiens (human)	Potency	3.9811	1
6-[[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]methyl]-N2-(3-methylphenyl)-1,3,5-triazine-2,4-diamine	Homo sapiens (human)	Potency	2.5119	1
2-methoxy-1-(1-methyl-2-benzimidazolyl)-1-phenylethanamine	Homo sapiens (human)	Potency	10.0000	1
2-[[[5-(3-chlorophenyl)-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]thio]methyl]-1H-benzimidazole	Homo sapiens (human)	Potency	10.0000	1
3-(4-methoxyphenyl)-2-(4-methyl-1-piperazinyl)-6,7,8,9-tetrahydro-5H-cyclohepta[2,3]thieno[2,4-b]pyrimidin-4-one	Homo sapiens (human)	Potency	3.1623	1
chlorprothixene	Homo sapiens (human)	Potency	12.5893	1
dienestrol	Homo sapiens (human)	Potency	15.8489	1
doxepin hydrochloride	Homo sapiens (human)	Potency	15.8489	1
ag-213	Homo sapiens (human)	Potency	18.8541	1
3,3',4,5'-tetrahydroxystilbene	Homo sapiens (human)	Potency	4.4668	1
sch-202676	Homo sapiens (human)	Potency	1.0000	1
5-(4-methoxyphenyl)-1,2-dihydro-1,2,4-triazole-3-thione	Homo sapiens (human)	Potency	39.8107	1
N-[(2-phenylethylamino)-sulfanylidenemethyl]benzamide	Homo sapiens (human)	Potency	12.5893	1
captax	Homo sapiens (human)	Potency	33.5520	1
2-[(3-methyl-6-oxo-7,8,9,10-tetrahydrobenzo[c][1]benzopyran-1-yl)oxy]acetic acid propan-2-yl ester	Homo sapiens (human)	Potency	0.1995	1
2-(1H-benzimidazol-2-ylthio)-1-(2,3-dimethyl-1-indolyl)ethanone	Homo sapiens (human)	Potency	25.1189	1
4,6-dimethyl-2-[[2-oxo-2-(1-piperidinyl)ethyl]thio]-3-pyridinecarbonitrile	Homo sapiens (human)	Potency	39.8107	1
4-chloro-N-(3,4,5-trimethoxyphenyl)-5-dithiazolimine	Homo sapiens (human)	Potency	25.1189	1
phenylthiazolylthiourea	Homo sapiens (human)	Potency	15.8489	1
1-ethyl-2-[[(1-methyl-2-benzimidazolyl)thio]methyl]benzimidazole	Homo sapiens (human)	Potency	3.9811	1
2-amino-4-(2-furanyl)-3-thiophenecarboxylic acid ethyl ester	Homo sapiens (human)	Potency	15.8489	1
2-(2,3-dihydroindol-1-yl)-N,N-dimethylethanamine	Homo sapiens (human)	Potency	25.1189	1
2-[[3-[(2-hydroxyphenyl)methyl]-1,3-diazinan-1-yl]methyl]phenol	Homo sapiens (human)	Potency	12.5893	1
N2,N4-ditert-butyl-6-hydrazinyl-1,3,5-triazine-2,4-diamine	Homo sapiens (human)	Potency	7.9433	1
4-(benzenesulfonyl)-5-(ethylthio)-2-phenyloxazole	Homo sapiens (human)	Potency	31.6228	1
cid755673	Homo sapiens (human)	Potency	1.0000	1
4-phenyl-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine	Homo sapiens (human)	Potency	31.6228	1
1-[(4-phenyl-1-piperazinyl)methyl]-2-naphthalenol	Homo sapiens (human)	Potency	39.8107	1
2-[[2-(5,6-dimethyl-1-benzimidazolyl)-1-oxoethyl]amino]benzoic acid methyl ester	Homo sapiens (human)	Potency	10.0000	1
N-(1-ethyl-5-benzimidazolyl)-4-methylbenzenesulfonamide	Homo sapiens (human)	Potency	39.8107	1
4-methyl-N-[1-[2-(1-pyrrolidinyl)ethyl]-2-benzimidazolyl]benzamide	Homo sapiens (human)	Potency	7.9433	1
4-tert-butyl-N-[2-(2-methoxyphenyl)ethyl]-1-cyclohexanamine	Homo sapiens (human)	Potency	25.1189	1
2-methoxy-4-[[2-(methylthio)anilino]methyl]phenol	Homo sapiens (human)	Potency	31.6228	1
1-[[3-(4-chlorophenoxy)phenyl]methyl]-4-ethylpiperazine	Homo sapiens (human)	Potency	15.8489	1
9-ethyl-1,2,4,5-tetrazaspiro[5.5]undecane-3-thione	Homo sapiens (human)	Potency	7.9433	1
1-(1,3-benzodioxol-5-ylmethyl)-3-(2,5-dimethylphenyl)thiourea	Homo sapiens (human)	Potency	25.1189	1
8-methyl-2-phenyl-1,2,4-triazaspiro[4.5]decane-3-thione	Homo sapiens (human)	Potency	6.3096	1
N-[[(2,4-dimethyl-8-quinolinyl)amino]-sulfanylidenemethyl]-4-methylbenzamide	Homo sapiens (human)	Potency	25.1189	1
N-methyl-2-(4-methylphenyl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine	Homo sapiens (human)	Potency	31.6228	1
6-[amino(methyl)amino]-N2,N4-diethyl-1,3,5-triazine-2,4-diamine	Homo sapiens (human)	Potency	3.1623	1
4-[(4-chlorophenyl)thio]-5-methyl-2-phenyl-1H-pyrazol-3-one	Homo sapiens (human)	Potency	10.0000	1
N-(2-furanylmethyl)-1-(4-methoxyphenyl)-5-benzimidazolamine	Homo sapiens (human)	Potency	12.5893	1
N-[3,4-dihydro-2H-quinolin-1-yl(sulfanylidene)methyl]-2-(3-methylphenoxy)acetamide	Homo sapiens (human)	Potency	19.9526	1
3-(1,3-benzodioxol-5-yl)-4-(2,5-dimethylphenyl)-1H-1,2,4-triazole-5-thione	Homo sapiens (human)	Potency	19.9526	1
4-(3-methylphenyl)-3-(5-propan-2-yl-3-thiophenyl)-1H-1,2,4-triazole-5-thione	Homo sapiens (human)	Potency	7.9433	1
4-(phenylmethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione	Homo sapiens (human)	Potency	12.5893	1
1-[2-(2-chlorophenoxy)ethyl]benzimidazole	Homo sapiens (human)	Potency	12.5893	1
5-[2-(6-hydroxy-3-methyl-2-benzofuranyl)-2-oxoethyl]-2-furancarboxylic acid ethyl ester	Homo sapiens (human)	Potency	25.1189	1
1-ethyl-N-[(4-methoxyphenyl)methyl]-5-benzimidazolamine	Homo sapiens (human)	Potency	31.6228	1
4-methoxy-2-[3-(4-methoxyphenyl)-5-methyl-1H-pyrazol-4-yl]phenol	Homo sapiens (human)	Potency	12.5893	1
3-bromo-N-[(tert-butylamino)-sulfanylidenemethyl]-4-methoxybenzamide	Homo sapiens (human)	Potency	15.8489	1
1-[(3-methylphenyl)methyl]benzimidazole	Homo sapiens (human)	Potency	31.6228	1
lupitidine	Homo sapiens (human)	Potency	31.6228	1
1-(cycloheptylideneamino)-3-(4-fluorophenyl)thiourea	Homo sapiens (human)	Potency	39.8107	1
4-methoxy-N-[[(phenylmethyl)amino]-sulfanylidenemethyl]benzamide	Homo sapiens (human)	Potency	10.0000	1
N-(2-ethoxyphenyl)-1H-benzimidazol-2-amine	Homo sapiens (human)	Potency	1.9953	1
2-(4-methyl-1-piperazinyl)-6-phenyl-4-pyrimidinecarbonitrile	Homo sapiens (human)	Potency	39.8107	1
thiothixene	Homo sapiens (human)	Potency	17.4882	1
6-methoxy-3-[(3-methylanilino)methyl]-1H-quinolin-2-one	Homo sapiens (human)	Potency	39.8107	1
curcumin	Homo sapiens (human)	Potency	7.9433	1
3-chloro-4-[(1-ethyl-2-benzimidazolyl)thio]aniline	Homo sapiens (human)	Potency	31.6228	1
1-[[(2-chlorophenyl)-oxomethyl]amino]-3-(2-methoxy-5-methylphenyl)thiourea	Homo sapiens (human)	Potency	15.8489	1
1-[[(5-bromo-2-furanyl)-oxomethyl]amino]-3-(2,5-dimethylphenyl)thiourea	Homo sapiens (human)	Potency	39.8107	1
9-hydroxy-4-[1-oxo-2-[4-(phenylmethyl)-1-piperazinyl]ethyl]-2,3-dihydro-1H-[1]benzopyrano[3,4-b]pyridin-5-one	Homo sapiens (human)	Potency	31.6228	1
4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(2,6-dimethylphenyl)benzamide	Homo sapiens (human)	Potency	39.8107	1
N-(1-ethyl-2-benzimidazolyl)-5-[(4-methyl-2-nitrophenoxy)methyl]-2-furancarboxamide	Homo sapiens (human)	Potency	10.0000	1
[3-amino-6-(4-methoxyphenyl)-2-thieno[2,3-b]pyridinyl]-(3,4-dimethoxyphenyl)methanone	Homo sapiens (human)	Potency	19.9526	1
1-[[2-(4-chlorophenyl)-1-oxoethyl]amino]-3-(1-naphthalenyl)urea	Homo sapiens (human)	Potency	25.1189	1
5-bromo-N-[[4-[(3,5-dimethylphenyl)sulfamoyl]anilino]-sulfanylidenemethyl]-2-furancarboxamide	Homo sapiens (human)	Potency	12.5893	1
N-[[3-chloro-4-(4-morpholinyl)anilino]-sulfanylidenemethyl]-2-(4-methoxyphenoxy)acetamide	Homo sapiens (human)	Potency	15.8489	1
N-[[3-chloro-4-(1-piperidinyl)anilino]-sulfanylidenemethyl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide	Homo sapiens (human)	Potency	10.0000	1
1,2,3,4-tetrahydroacridine-9-carboxylic acid (2-oxo-2-thiophen-2-ylethyl) ester	Homo sapiens (human)	Potency	31.6228	1
N-[2-[2-[2-(4-ethoxyanilino)-2-oxoethyl]-5-tetrazolyl]phenyl]-2-thiophenecarboxamide	Homo sapiens (human)	Potency	15.8489	1
N-[2-(2-pyridinyl)-3H-benzimidazol-5-yl]cyclohexanecarboxamide	Homo sapiens (human)	Potency	5.0119	1
5-(3-chlorophenyl)-N-(2-propyl-5-tetrazolyl)-2-furancarboxamide	Homo sapiens (human)	Potency	0.2512	1
N-[4-[[2-furanyl(oxo)methyl]amino]phenyl]-1,3-benzodioxole-5-carboxamide	Homo sapiens (human)	Potency	19.9526	1
1-[4-[3-[5-(2-furanyl)-1H-pyrazol-3-yl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]phenyl]ethanone	Homo sapiens (human)	Potency	19.9526	1
N-[3-[2-[(4-methyl-2-pyridinyl)amino]-4-thiazolyl]phenyl]acetamide	Homo sapiens (human)	Potency	31.6228	1
5-(4-bromophenyl)-1-methyl-N-(3-pyridinylmethyl)-2-imidazolamine	Homo sapiens (human)	Potency	19.9526	1
N'-methyl-N-[1-methyl-5-(4-methylphenyl)-2-imidazolyl]-N'-(phenylmethyl)butanediamide	Homo sapiens (human)	Potency	31.6228	1
4-chloro-3-(1-piperidinylsulfonyl)-N-(2-thiazolyl)benzamide	Homo sapiens (human)	Potency	25.1189	1
ym-90709	Homo sapiens (human)	Potency	25.1189	1
2-(1,3-benzodioxol-5-yl)-N-[(2-ethoxyphenyl)methyl]-N-(2-pyridinylmethyl)ethanamine	Homo sapiens (human)	Potency	25.1189	1
2-[(7-methoxy-4-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)thio]-N-methyl-N-(4-phenyl-2-thiazolyl)acetamide	Homo sapiens (human)	Potency	25.1189	1
N-[2,5-diethoxy-4-[[(3-methoxyanilino)-sulfanylidenemethyl]amino]phenyl]-4-methylbenzamide	Homo sapiens (human)	Potency	19.9526	1
N-[4-[[anilino(sulfanylidene)methyl]amino]-2,5-diethoxyphenyl]-4-methoxybenzamide	Homo sapiens (human)	Potency	25.1189	1
N-[4-[[anilino(sulfanylidene)methyl]amino]-2,5-diethoxyphenyl]benzamide	Homo sapiens (human)	Potency	25.1189	1
N-(2-furanylmethyl)-2-(4-oxo-6-phenyl-3-thieno[2,3-d]pyrimidinyl)acetamide	Homo sapiens (human)	Potency	31.6228	1
4-(5,6-dimethyl-1-benzimidazolyl)-5-phenylthieno[2,3-d]pyrimidine	Homo sapiens (human)	Potency	25.1189	1
benztropine	Homo sapiens (human)	Potency	19.9526	1
1-(2-chloro-10-phenothiazinyl)-2-[(1-methyl-5-tetrazolyl)thio]ethanone	Homo sapiens (human)	Potency	6.3096	1
N-[(1,2-dihydroacenaphthylen-5-ylamino)-sulfanylidenemethyl]-2-phenoxyacetamide	Homo sapiens (human)	Potency	15.8489	1
3-[[[2-(3-methylphenyl)-4-quinolinyl]-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester	Homo sapiens (human)	Potency	19.9526	1
1-[[2-(3-bromo-4-methoxyphenyl)-1-oxoethyl]amino]-3-phenylthiourea	Homo sapiens (human)	Potency	1.5849	1
3,5-dimethoxy-N-[(2-phenylethylamino)-sulfanylidenemethyl]benzamide	Homo sapiens (human)	Potency	7.9433	1
1,4-dioxa-8-azaspiro[4.5]decan-8-yl(4,5,6,7-tetrahydro-1-benzothiophen-2-yl)methanone	Homo sapiens (human)	Potency	7.9433	1
N-[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]-3-pyridinecarboxamide	Homo sapiens (human)	Potency	39.8107	1
N-[(3-methoxyphenyl)methyl]-1-propyl-5-benzimidazolamine	Homo sapiens (human)	Potency	12.5893	1
LSM-33266	Homo sapiens (human)	Potency	25.1189	1
N-[2-methoxy-5-(2-oxo-1-benzopyran-3-yl)phenyl]-5-nitro-2-furancarboxamide	Homo sapiens (human)	Potency	25.1189	1
N-[[3-chloro-2-(4-morpholinyl)anilino]-sulfanylidenemethyl]-4-methoxy-3-nitrobenzamide	Homo sapiens (human)	Potency	12.5893	1
N-[[3-chloro-2-(1-piperidinyl)anilino]-sulfanylidenemethyl]-2-thiophenecarboxamide	Homo sapiens (human)	Potency	19.9526	1
2-(1-imidazolyl)-4-phenyl-6-(4-phenyl-1-piperazinyl)-1,3,5-triazine	Homo sapiens (human)	Potency	10.0000	1
2-[[(3,4-dimethoxyphenyl)-oxomethyl]amino]-N-(2-furanylmethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide	Homo sapiens (human)	Potency	31.6228	1
2-(1,3-benzodioxol-5-ylmethylthio)-5-(2-furanyl)-3-prop-2-enyl-4-thieno[2,3-d]pyrimidinone	Homo sapiens (human)	Potency	1.0000	1
darunavir ethanolate	Homo sapiens (human)	Potency	25.1189	1
[1-(2-phenoxyethyl)-3-indolyl]-(1-pyrrolidinyl)methanethione	Homo sapiens (human)	Potency	25.1189	1
3-[[[(1-oxo-2,2-diphenylethyl)amino]-sulfanylidenemethyl]amino]benzoic acid	Homo sapiens (human)	Potency	15.8489	1
2-chloro-5-[[[[(3,5-dimethoxyphenyl)-oxomethyl]amino]-sulfanylidenemethyl]amino]benzoic acid	Homo sapiens (human)	Potency	12.5893	1
2-[2,5-dimethyl-3-[(2,4,6-trioxo-1,3-diazinan-5-ylidene)methyl]-1-pyrrolyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl ester	Homo sapiens (human)	Potency	10.0000	1
1-[2,3-bis(2-furanyl)-6-quinoxalinyl]-3-[4-(4-morpholinyl)phenyl]thiourea	Homo sapiens (human)	Potency	25.1189	1
N-[[4-(4-chlorophenoxy)anilino]-sulfanylidenemethyl]benzamide	Homo sapiens (human)	Potency	12.5893	1
N-[[5-(5,7-dimethyl-1,3-benzoxazol-2-yl)-2-methylanilino]-sulfanylidenemethyl]-2-thiophenecarboxamide	Homo sapiens (human)	Potency	6.3096	1
3-(3-oxo-2-benzo[f][1]benzopyranyl)-1-phenyl-4-pyrazolecarboxaldehyde	Homo sapiens (human)	Potency	19.9526	1
N-(2,3-dimethylphenyl)-2-[[6-(1,3-dioxo-2-isoindolyl)-1,3-benzothiazol-2-yl]thio]acetamide	Homo sapiens (human)	Potency	19.9526	1
3-[(1,3-benzothiazol-2-ylthio)methyl]-4-cyclohexyl-1H-1,2,4-triazole-5-thione	Homo sapiens (human)	Potency	15.8489	1
5-(3-nitrophenyl)-N-[[2-(1-pyrrolidinyl)anilino]-sulfanylidenemethyl]-2-furancarboxamide	Homo sapiens (human)	Potency	7.9433	1
5,6-dimethyl-2-[1-[[1-(phenylmethyl)-5-tetrazolyl]methyl]-4-piperidinyl]-1H-benzimidazole	Homo sapiens (human)	Potency	25.1189	1
2-[(2-propyl-4-quinazolinyl)thio]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide	Homo sapiens (human)	Potency	31.6228	1
1-[2-(5,6-dimethyl-1H-benzimidazol-2-yl)ethyl]-3-(2-methoxyphenyl)-1-(3-pyridinylmethyl)thiourea	Homo sapiens (human)	Potency	3.1623	1
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-phenylethyl)acetamide	Homo sapiens (human)	Potency	0.3162	1
N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-[4-[5-(trifluoromethyl)-1-benzotriazolyl]-1-piperidinyl]acetamide	Homo sapiens (human)	Potency	25.1189	1
4-chloro-N-(4-chloro-2-methylphenyl)-5-dithiazolimine	Homo sapiens (human)	Potency	39.8107	1
7-(4-methoxyphenyl)-2-(1-pyrrolyl)-[1,2,4]triazolo[1,5-a]pyrimidine	Homo sapiens (human)	Potency	31.6228	1
4-[(4-chloro-1-naphthalenyl)oxy]-5-methoxy-2-(2-pyridinyl)pyrimidine	Homo sapiens (human)	Potency	3.9811	1
N-[(4-methylphenyl)methyl]-2-(2-pyridinyl)-4-(trifluoromethyl)-5-pyrimidinecarboxamide	Homo sapiens (human)	Potency	25.1189	1
3-[4-ethyl-5-[(4-methylphenyl)methylthio]-1,2,4-triazol-3-yl]-1-phenyl-4-pyridazinone	Homo sapiens (human)	Potency	25.1189	1
1,1-bis(4-chlorophenyl)-2-[(3-methoxyphenyl)methylamino]ethanol	Homo sapiens (human)	Potency	19.9526	1
2-[(2,4-dichlorophenyl)methylthio]-6,7-dimethoxy-3-(thiophen-2-ylmethyl)-4-quinazolinimine	Homo sapiens (human)	Potency	15.8489	1
fluoxetine	Homo sapiens (human)	Potency	13.8725	1
terbinafine	Homo sapiens (human)	Potency	25.1189	1
4-(4-methylphenyl)-2-[[oxo-(2-oxo-1-benzopyran-3-yl)methyl]amino]-3-thiophenecarboxylic acid ethyl ester	Homo sapiens (human)	Potency	25.1189	1
3-propoxy-N-[sulfanylidene-[3-(trifluoromethyl)anilino]methyl]benzamide	Homo sapiens (human)	Potency	19.9526	1
N-[[3-chloro-4-(1-piperidinyl)anilino]-sulfanylidenemethyl]hexanamide	Homo sapiens (human)	Potency	15.8489	1
N-[3-(dimethylamino)propyl]-9H-carbazole-3-carboxamide	Homo sapiens (human)	Potency	25.1189	1
N-[[[2-(2-methoxyphenoxy)-1-oxoethyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamide	Homo sapiens (human)	Potency	3.1623	1
1-ethyl-3-[[[2-(2-methylpropyl)-4-quinolinyl]-oxomethyl]amino]thiourea	Homo sapiens (human)	Potency	15.8489	1
3-bromo-4-methoxy-N-[(propan-2-ylamino)-sulfanylidenemethyl]benzamide	Homo sapiens (human)	Potency	12.5893	1
2-(2-methoxyethylthio)-N-(2-thiazolyl)benzamide	Homo sapiens (human)	Potency	19.9526	1
1-[2-(2-methylphenoxy)ethyl]-3-phenylthiourea	Homo sapiens (human)	Potency	12.5893	1
N4-ethyl-6-[2-(4-methylphenoxy)ethylthio]-N2-propan-2-yl-1,3,5-triazine-2,4-diamine	Homo sapiens (human)	Potency	25.1189	1
2-[[2-(3,5-dimethyl-1-pyrazolyl)-6-methyl-4-pyrimidinyl]amino]ethanol	Homo sapiens (human)	Potency	25.1189	1
1-[(3,4-dichlorophenyl)methyl]indole-2,3-dione	Homo sapiens (human)	Potency	7.9433	1
4-(phenylmethyl)-3-[2-(4-propoxyphenyl)ethyl]-1H-1,2,4-triazole-5-thione	Homo sapiens (human)	Potency	12.5893	1
2-[[[2-amino-1-(3-methoxypropyl)-3-pyrrolo[3,2-b]quinoxalinyl]-oxomethyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl ester	Homo sapiens (human)	Potency	3.1623	1
2-[[4-amino-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]thio]-N-(9-ethyl-3-carbazolyl)acetamide	Homo sapiens (human)	Potency	15.8489	1
2-[(2-methyl-4-benzofuro[3,2-d]pyrimidinyl)thio]-N-(phenylmethyl)acetamide	Homo sapiens (human)	Potency	31.6228	1
N-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-4-[methyl-(phenylmethyl)sulfamoyl]benzamide	Homo sapiens (human)	Potency	31.6228	1
3-[3-[[2-oxo-2-(1,2,5-trimethyl-3-pyrrolyl)ethyl]thio]propyl]-1H-benzimidazol-2-one	Homo sapiens (human)	Potency	25.1189	1
4-(2,3-dihydroindol-1-ylmethyl)-7-ethyl-1-benzopyran-2-one	Homo sapiens (human)	Potency	25.1189	1
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-ethyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanone	Homo sapiens (human)	Potency	19.9526	1
3-[[4-(2-benzofuranyl)-2-thiazolyl]methyl]-2-[(dimethylamino)methyl]-4-quinazolinone	Homo sapiens (human)	Potency	7.9433	1
N-(2-methyl-1,3-benzothiazol-6-yl)-2,3-dihydro-1,4-benzodioxin-6-sulfonamide	Homo sapiens (human)	Potency	39.8107	1
3-[(4-acetyl-1-piperazinyl)sulfonyl]-N-(1H-benzimidazol-2-yl)benzamide	Homo sapiens (human)	Potency	39.8107	1
N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-2-quinolinecarboxamide	Homo sapiens (human)	Potency	25.1189	1
2-(2-fluorophenoxy)-N-[4-(2-furanylmethylsulfamoyl)phenyl]acetamide	Homo sapiens (human)	Potency	3.9811	1
4-(4-tert-butylphenoxy)-N-(4,5-dihydrothiazol-2-yl)butanamide	Homo sapiens (human)	Potency	15.8489	1
4-[ethyl-(phenylmethyl)sulfamoyl]-N-[5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamide	Homo sapiens (human)	Potency	3.1623	1
4-[bis(2-methylpropyl)sulfamoyl]-N-[5-(3-methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamide	Homo sapiens (human)	Potency	5.0119	1
1-(2,5-dimethoxyphenyl)-3-[2-(trifluoromethyl)-1,3-benzodioxol-2-yl]urea	Homo sapiens (human)	Potency	10.0000	1
N9-(4-butoxyphenyl)-6,8,10-triazaspiro[4.5]deca-6,9-diene-7,9-diamine	Homo sapiens (human)	Potency	25.1189	1
N-[4-(dibutylsulfamoyl)phenyl]-2-thiophen-2-ylacetamide	Homo sapiens (human)	Potency	25.1189	1
4-[(2,4-dichlorophenoxy)methyl]-N-[2-(dimethylamino)ethyl]benzamide	Homo sapiens (human)	Potency	7.9433	1
N-(2-furanylmethyl)-2-(6,7,8,9-tetrahydro-5H-cyclohepta[2,3]thieno[2,4-d]pyrimidin-4-ylthio)acetamide	Homo sapiens (human)	Potency	25.1189	1
2-(2-bromo-4-tert-butylphenoxy)-N-(2-furanylmethyl)acetamide	Homo sapiens (human)	Potency	15.8489	1
2-((3-(2,3-dichlorophenoxy)propyl)amino)ethanol	Homo sapiens (human)	Potency	12.5893	1
N-(2,1,3-benzothiadiazol-4-yl)-5-(3-chlorophenyl)-2-furancarboxamide	Homo sapiens (human)	Potency	12.5893	1
3,4-dimethyl-N-[sulfanylidene-[2-(trifluoromethyl)anilino]methyl]benzamide	Homo sapiens (human)	Potency	25.1189	1
8-[2-(4-chloro-3,5-dimethylphenoxy)ethoxy]quinoline	Homo sapiens (human)	Potency	15.8489	1
1-chloro-2-[2-(2-methoxy-4-methylphenoxy)ethoxy]-4-methylbenzene	Homo sapiens (human)	Potency	15.8489	1
8-[3-(3,4-dimethylphenoxy)propoxy]quinoline	Homo sapiens (human)	Potency	31.6228	1
N-(3-dibenzofuranyl)-2-[2-oxo-2-(2,4,6-trimethylanilino)ethoxy]benzamide	Homo sapiens (human)	Potency	19.9526	1
2-(4,6-dimethyl-2-pyrimidinyl)-4-[(4-fluorophenyl)thio]-5-methyl-3-pyrazolamine	Homo sapiens (human)	Potency	7.9433	1
2-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-1,2-benzothiazol-3-one	Homo sapiens (human)	Potency	0.6310	1
5-[(2-chlorophenyl)hydrazo]-3,3-bis(hydroxymethyl)-2H-1,4-oxazin-6-one	Homo sapiens (human)	Potency	15.8489	1
N-(5-methyl-3-isoxazolyl)-2-(2-naphthalenylthio)acetamide	Homo sapiens (human)	Potency	15.8489	1
3-(1-azepanylsulfonyl)-4-chloro-N-(1H-1,2,4-triazol-5-yl)benzamide	Homo sapiens (human)	Potency	1.2589	1
5-(4-propylphenyl)-1H-pyrazol-3-amine	Homo sapiens (human)	Potency	25.1189	1
3-(4-tert-butylphenoxy)-N-(4,5-dihydrothiazol-2-yl)propanamide	Homo sapiens (human)	Potency	19.9526	1
2-(1-benzimidazolyl)acetic acid [2-[1-(4-methoxyphenyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] ester	Homo sapiens (human)	Potency	12.5893	1
N-(6-methoxy-1,3-benzothiazol-2-yl)-3-(4-morpholinylsulfonyl)benzamide	Homo sapiens (human)	Potency	39.8107	1
3-[2-(2-furanylmethylamino)-2-oxoethoxy]-N-(2-methoxy-5-methylphenyl)-2-naphthalenecarboxamide	Homo sapiens (human)	Potency	15.8489	1
4,6,8-trimethyl-1H-quinoline-2-thione	Homo sapiens (human)	Potency	25.1189	1
N-[4-(4-methoxyphenyl)-2-thiazolyl]-5-methyl-2-phenyl-4-oxazolecarboxamide	Homo sapiens (human)	Potency	25.1189	1
5-[[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)thio]methyl]-2-furancarboxylic acid methyl ester	Homo sapiens (human)	Potency	25.1189	1
5-[2-[[2-[[2-furanyl(oxo)methyl]amino]phenyl]-oxomethoxy]-1-oxoethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester	Homo sapiens (human)	Potency	0.1585	1
2-[[[4-cyclohexyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one	Homo sapiens (human)	Potency	15.8489	1
2-[[4-amino-6-(2-methylanilino)-1,3,5-triazin-2-yl]methyl-methylamino]-N-(2-ethylphenyl)acetamide	Homo sapiens (human)	Potency	1.9953	1
4-chloro-N-[3-[(3,5-dimethyl-4-isoxazolyl)methylthio]-2-quinoxalinyl]benzenesulfonamide	Homo sapiens (human)	Potency	31.6228	1
N-[5-chloro-2-(4-methyl-1-piperazinyl)phenyl]-3-(dimethylsulfamoyl)benzamide	Homo sapiens (human)	Potency	10.0000	1
3-(diethylsulfamoyl)-N-(3,5-dimethylphenyl)benzamide	Homo sapiens (human)	Potency	0.1585	1
5-chloro-2-mercaptobenzothiazole	Homo sapiens (human)	Potency	25.1189	1
malachite green	Homo sapiens (human)	Potency	5.0119	1
capsazepine	Homo sapiens (human)	Potency	12.5893	1
tamoxifen citrate	Homo sapiens (human)	Potency	10.8631	1
tamoxifen	Homo sapiens (human)	Potency	6.3096	1
tetraoctylammonium bromide	Homo sapiens (human)	Potency	31.6228	1
4-(benzenesulfonyl)-1-[(4-chlorophenyl)methyl]-4-piperidinecarboxylic acid ethyl ester	Homo sapiens (human)	Potency	39.8107	1
2-[[sulfanylidene-[[2,2,2-trichloro-1-[[(2-nitrophenyl)-oxomethyl]amino]ethyl]amino]methyl]amino]benzoic acid	Homo sapiens (human)	Potency	10.0000	1
2-[[sulfanylidene-[[2,2,2-trichloro-1-[(1-oxo-2-phenoxyethyl)amino]ethyl]amino]methyl]amino]benzoic acid	Homo sapiens (human)	Potency	10.0000	1
N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-2-adamantanamine	Homo sapiens (human)	Potency	25.1189	1
1-(5-bicyclo[2.2.1]hept-2-enylmethyl)-4-[3-(trifluoromethyl)phenyl]piperazine	Homo sapiens (human)	Potency	15.8489	1
3,5,7-trimethyl-N-[4-morpholinyl(sulfanylidene)methyl]-1-adamantanecarboxamide	Homo sapiens (human)	Potency	19.9526	1
3,7-dimethyl-2-[4-(2-pyridinyl)-1-piperazinyl]quinoline	Homo sapiens (human)	Potency	19.9526	1
1-(3,5-dichlorophenyl)-3-(4-morpholinyl)pyrrolidine-2,5-dione	Homo sapiens (human)	Potency	25.1189	1
4-ethyl-2-methoxy-3-phenyl-3,3a,9,9a-tetrahydropyrrolo[2,3-b]quinoxaline	Homo sapiens (human)	Potency	15.8489	1
3-[2-[4-(2-chloro-4-nitrophenyl)-1-piperazinyl]ethoxy]-4-phenyl-1,2,5-oxadiazole	Homo sapiens (human)	Potency	31.6228	1
N-[4-bromo-2-[[(2-hydrazinyl-2-oxoethyl)amino]-phenylmethyl]phenyl]-3-(4-morpholinyl)propanamide	Homo sapiens (human)	Potency	25.1189	1
N-[5-[(4-methylphenyl)methyl]-2-thiazolyl]-2-oxolanecarboxamide	Homo sapiens (human)	Potency	31.6228	1
N-cyclohexyl-4-(4-nitrophenyl)-1-piperazinecarbothioamide	Homo sapiens (human)	Potency	25.1189	1
2,2'-[3-(2-methoxyphenyl)-1,2-propanediyl]bis(1H-benzimidazole)	Homo sapiens (human)	Potency	0.0794	1
N-(1-butyl-2-benzimidazolyl)cyclohexanecarboxamide	Homo sapiens (human)	Potency	10.0000	1
N-(3,3,5-trimethylcyclohexyl)-1H-1,2,4-triazole-5-carboxamide	Homo sapiens (human)	Potency	39.8107	1
4-methylbenzenesulfonic acid [4-[bis(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-2-methoxyphenyl] ester	Homo sapiens (human)	Potency	25.1189	1
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]-N-[2-(4-morpholinyl)ethyl]acetamide	Homo sapiens (human)	Potency	3.1623	1
1-[4-(3-ethoxyphenoxy)butyl]imidazole	Homo sapiens (human)	Potency	15.8489	1
4-methylbenzenesulfonic acid [4-[bis(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-2-ethoxyphenyl] ester	Homo sapiens (human)	Potency	10.0000	1
1-(2-furanylmethyl)-3-[(4-methylphenyl)methyl]pyrrolidine-2,5-dione	Homo sapiens (human)	Potency	25.1189	1
benzenesulfonic acid [4-[bis(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-2-methoxyphenyl] ester	Homo sapiens (human)	Potency	7.9433	1
benzenesulfonic acid [4-[bis(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-2-ethoxyphenyl] ester	Homo sapiens (human)	Potency	25.1189	1
2-[[1-(4-chlorophenyl)-2,5-dioxo-3-pyrrolidinyl]-methylamino]acetic acid methyl ester	Homo sapiens (human)	Potency	12.5893	1
1-(2,4-dimethoxyphenyl)-3-[4-(4-morpholinyl)anilino]pyrrolidine-2,5-dione	Homo sapiens (human)	Potency	31.6228	1
N-(4,5-dihydrothiazol-2-yl)-3,5-dimethyl-1-adamantanecarboxamide	Homo sapiens (human)	Potency	15.8489	1
4-[[[4-(2-furanylmethyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]benzonitrile	Homo sapiens (human)	Potency	31.6228	1
4-[cyclohexyl(methyl)amino]-N-(6-methyl-2-pyridinyl)-3-nitrobenzamide	Homo sapiens (human)	Potency	19.9526	1
4-(2,5-dimethylphenyl)-6-[[(4-methylphenyl)methylamino]methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylic acid ethyl ester	Homo sapiens (human)	Potency	12.5893	1
4-(1,3-benzodioxol-5-yl)-6-[[2-(4-chlorophenyl)ethylamino]methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylic acid ethyl ester	Homo sapiens (human)	Potency	39.8107	1
nsc 727447	Homo sapiens (human)	Potency	31.6228	1
1-[(6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl)methoxy]-3-(1-methyl-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazin-2-yl)-2-propanol	Homo sapiens (human)	Potency	15.8489	1
2-(4-anilinophenoxy)acetic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester	Homo sapiens (human)	Potency	15.8489	1
4-chloro-N-(1-propyl-2-benzimidazolyl)-3-(1-pyrrolidinylsulfonyl)benzamide	Homo sapiens (human)	Potency	31.6228	1
2-chloro-N-[5-chloro-2-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamide	Homo sapiens (human)	Potency	12.5893	1
3-(2,5-dimethyl-3-furanyl)-5,6-diphenyl-1,2,4-triazine	Homo sapiens (human)	Potency	10.0000	1
bis(1-ethenyl-2-imidazolyl)-(9-ethyl-3-carbazolyl)-sulfanylidenephosphorane	Homo sapiens (human)	Potency	3.1623	1
N-[1-oxo-1-[[4-(2-pyridinyl)-2-thiazolyl]amino]propan-2-yl]-2-furancarboxamide	Homo sapiens (human)	Potency	25.1189	1
N-[2-(2,4-dichlorophenyl)ethyl]-2-[[5-[1-(dimethylamino)propyl]-1,3,4-oxadiazol-2-yl]thio]acetamide	Homo sapiens (human)	Potency	15.8489	1
2-(2-furanyl)-N-(2-oxolanylmethyl)-4-quinolinecarboxamide	Homo sapiens (human)	Potency	12.5893	1
N-(1-propyl-2-benzimidazolyl)-3-(1-pyrrolidinylsulfonyl)benzamide	Homo sapiens (human)	Potency	31.6228	1
1,4-dimethoxy-10H-acridine-9-thione	Homo sapiens (human)	Potency	7.9433	1
l 783281	Homo sapiens (human)	Potency	39.8107	1
altanserin	Homo sapiens (human)	Potency	31.6228	1
4-phenyl-1-(4-phenylbutyl)piperidine	Homo sapiens (human)	Potency	10.0000	1
triptorelin	Homo sapiens (human)	Potency	2.5119	1
thioperamide	Homo sapiens (human)	Potency	7.9433	1
bp 897	Homo sapiens (human)	Potency	6.3096	1
homoquinolinic acid	Homo sapiens (human)	Potency	19.9526	1
ici 199441	Homo sapiens (human)	Potency	12.5893	1
2-(2,4-dioxo-3-phenyl-5-thiazolidinyl)-N-(3-methylphenyl)acetamide	Homo sapiens (human)	Potency	15.8489	1
3-(4-fluorophenyl)-5-(2-furanyl)-2-phenyl-3,4-dihydropyrazole	Homo sapiens (human)	Potency	3.1623	1
2-[(prop-2-enylthio)-(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]propanedinitrile	Homo sapiens (human)	Potency	19.9526	1
2-chloro-N-[1-[oxo(10-phenothiazinyl)methyl]-4-piperidinyl]benzamide	Homo sapiens (human)	Potency	19.9526	1
N-(3-chlorophenyl)-4-[4-(3-methoxyphenyl)-2-thiazolyl]-1-piperazinecarbothioamide	Homo sapiens (human)	Potency	19.9526	1
3-(5-methyl-2-furanyl)-5-[1-(2-naphthalenylsulfonyl)-3-piperidinyl]-1,2,4-oxadiazole	Homo sapiens (human)	Potency	12.5893	1
1-(2-methyl-2,3-dihydroindol-1-yl)-2-[4-[5-(trifluoromethyl)-1-benzotriazolyl]-1-piperidinyl]ethanone	Homo sapiens (human)	Potency	12.5893	1
1-(1-tert-butyl-5-tetrazolyl)-N-(phenylmethyl)-1-(3-pyridinyl)-N-(thiophen-2-ylmethyl)methanamine	Homo sapiens (human)	Potency	25.1189	1
7-(2-ethyl-1-piperidinyl)-5-methyl-2-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine	Homo sapiens (human)	Potency	39.8107	1
N-[4-[1-(benzenesulfonyl)-2,3-dihydroindol-5-yl]-5-methyl-2-thiazolyl]-2-(4-morpholinyl)acetamide	Homo sapiens (human)	Potency	19.9526	1
6-(1,3-benzodioxol-5-yl)-N-[(3-methylphenyl)methyl]-4-quinazolinamine	Homo sapiens (human)	Potency	6.3096	1
6-(2-chlorophenyl)-N-(3-pyridinylmethyl)-4-quinazolinamine	Homo sapiens (human)	Potency	19.9526	1
6-(3-furanyl)-N-[(3-methylphenyl)methyl]-4-quinazolinamine	Homo sapiens (human)	Potency	25.1189	1
6-(3-pyridinyl)-N-(3-pyridinylmethyl)-4-quinazolinamine	Homo sapiens (human)	Potency	25.1189	1
6-(3-methoxyphenyl)-N-(3-pyridinylmethyl)-4-quinazolinamine	Homo sapiens (human)	Potency	25.1189	1
6-(2-chlorophenyl)-N-(2-furanylmethyl)-N-methyl-4-quinazolinamine	Homo sapiens (human)	Potency	39.8107	1
N-[(3-methylphenyl)methyl]-6-(3-pyridinyl)-4-quinazolinamine	Homo sapiens (human)	Potency	3.9811	1
N-(2,4-dimethoxyphenyl)-2-[1-(3,4-dimethylphenyl)-4-oxo-5-pyrazolo[3,4-d]pyrimidinyl]acetamide	Homo sapiens (human)	Potency	25.1189	1
N-[2-(1-cyclohexenyl)ethyl]-3-(1,3-dioxo-2-isoindolyl)propanamide	Homo sapiens (human)	Potency	12.5893	1
3-[4-[(2-hydroxy-5-phenylphenyl)methyl]-1-piperazinyl]propanenitrile	Homo sapiens (human)	Potency	19.9526	1
2-[(6-fluoro-1,3-benzothiazol-2-yl)amino]-4-thiazolecarboxylic acid ethyl ester	Homo sapiens (human)	Potency	3.9811	1
N-[3-(1-azepanyl)propyl]-1-[(4-methoxyphenyl)methyl]-5-oxo-3-pyrrolidinecarboxamide	Homo sapiens (human)	Potency	25.1189	1
N-[3-(diethylamino)propyl]-6-(4-fluorophenyl)-3-methyl-2-imidazo[2,1-b]thiazolecarboxamide	Homo sapiens (human)	Potency	31.6228	1
1-(4-bromophenyl)sulfonyl-4-[(3-methoxyphenyl)methyl]-1,4-diazepane	Homo sapiens (human)	Potency	25.1189	1
1-(4-methyl-2-prop-2-enylphenoxy)-3-(4-phenyl-1-piperazinyl)-2-propanol	Homo sapiens (human)	Potency	19.9526	1
5-(phenylmethoxymethyl)-7-(1-piperidinylmethyl)-8-quinolinol	Homo sapiens (human)	Potency	1.5849	1
4-(2,3-dihydroindol-1-yl)-N-[3-(N-ethyl-3-methylanilino)propyl]-3-(1-imidazolyl)-4-oxobutanamide	Homo sapiens (human)	Potency	2.5119	1
2-(6-benzimidazolo[1,2-c]quinazolinylthio)-N-(2-furanylmethyl)acetamide	Homo sapiens (human)	Potency	12.5893	1
N-[3-(1-imidazolyl)propyl]-7-methoxy-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide	Homo sapiens (human)	Potency	7.9433	1
N-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-2-[[1-oxo-2-(1-oxo-2-isoquinolinyl)ethyl]amino]acetamide	Homo sapiens (human)	Potency	19.9526	1
1-[bis(prop-2-enyl)amino]-3-(9-carbazolyl)-2-propanol	Homo sapiens (human)	Potency	19.9526	1
LSM-18934	Homo sapiens (human)	Potency	25.1189	1
2-(2,4-dimethoxyanilino)-N-[3-(4-methyl-1-piperazinyl)propyl]-4-quinolinecarboxamide	Homo sapiens (human)	Potency	25.1189	1
6-(1,3-benzodioxol-5-ylmethylamino)-3-(2-methylphenyl)-1H-pyrimidine-2,4-dione	Homo sapiens (human)	Potency	6.3096	1
4-[[2-(3-ethylanilino)-3,4-dioxo-1-cyclobutenyl]amino]-1-piperidinecarboxylic acid ethyl ester	Homo sapiens (human)	Potency	12.5893	1
N-[3-(1-azepanyl)propyl]-2-(4-morpholinyl)-3-oxo-4H-1,4-benzothiazine-6-carboxamide	Homo sapiens (human)	Potency	31.6228	1
3-(2-furanylmethyl)-5-(2-methoxyethyl)-1,3,5-thiadiazinane-2-thione	Homo sapiens (human)	Potency	15.8489	1
[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-(7-methoxy-2-furo[2,3-b]quinolinyl)methanone	Homo sapiens (human)	Potency	25.1189	1
7-[(4-methyl-1-piperazinyl)methyl]-5-(phenylmethoxymethyl)-8-quinolinol	Homo sapiens (human)	Potency	1.5849	1
3-methyl-N-[2-(4-morpholinyl)ethyl]-1-phenyl-5-thieno[2,3-c]pyrazolecarboxamide	Homo sapiens (human)	Potency	15.8489	1
N-(3,4-dimethylphenyl)-3-[(4-fluorophenyl)methyl]-1,3-diazinane-1-carboxamide	Homo sapiens (human)	Potency	31.6228	1
1-[3-[4-(2-fluorophenyl)-1-piperazinyl]propyl]-3-[4-(methylthio)phenyl]urea	Homo sapiens (human)	Potency	25.1189	1
7-(5-chloro-2-methoxyanilino)-6-[(4-methoxyphenyl)methyl]-7H-pyrrolo[3,4-b]pyridin-5-one	Homo sapiens (human)	Potency	25.1189	1
N-[2-[4-(3-chlorophenyl)-1-piperazinyl]ethyl]-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine	Homo sapiens (human)	Potency	25.1189	1
LSM-16579	Homo sapiens (human)	Potency	12.5893	1
N-(4-fluorophenyl)-6-methyl-1-propyl-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazine-2-carboxamide	Homo sapiens (human)	Potency	39.8107	1
N-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-2-[(1-ethyl-2-oxo-4-quinolinyl)oxy]acetamide	Homo sapiens (human)	Potency	25.1189	1
1-[[5-methyl-2-(2-methylphenyl)-4-oxazolyl]methyl]-N-(3-pyridinylmethyl)-4-piperidinecarboxamide	Homo sapiens (human)	Potency	25.1189	1
7-(2,4-dichlorophenyl)-5-oxo-2,3-dihydrothiazolo[3,2-a]pyrimidine-6-carbonitrile	Homo sapiens (human)	Potency	19.9526	1
N-[3-(3,5-dimethyl-1-piperidinyl)propyl]-1-[[5-methyl-2-(2-methylphenyl)-4-oxazolyl]methyl]-4-piperidinecarboxamide	Homo sapiens (human)	Potency	15.8489	1
5-(1,3-benzodioxol-5-yl)-3-[3-(methylthio)phenyl]-1H-imidazol-2-one	Homo sapiens (human)	Potency	15.8489	1
2-[2,4-dioxo-3-(phenylmethyl)-1-quinazolinyl]-N-(5-methyl-3-isoxazolyl)acetamide	Homo sapiens (human)	Potency	19.9526	1
N-cyclopentyl-4-(3,4-dimethoxyphenyl)-6-(trifluoromethyl)-2-pyrimidinamine	Homo sapiens (human)	Potency	0.2512	1
2-[[3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]thio]-N-(2-oxolanylmethyl)acetamide	Homo sapiens (human)	Potency	39.8107	1
N-[3-(cyclohexylthio)propyl]-1-[(4-methyl-5-thieno[3,2-b]pyrrolyl)-oxomethyl]-3-piperidinecarboxamide	Homo sapiens (human)	Potency	25.1189	1
1-[3-[2-(dimethylamino)ethylamino]-3-oxopropyl]-2-methyl-5-(4-methylphenyl)-3-pyrrolecarboxylic acid ethyl ester	Homo sapiens (human)	Potency	12.5893	1
1-[(2-ethoxyphenyl)methyl]-3-thiophen-2-ylurea	Homo sapiens (human)	Potency	22.3872	1
cambinol	Homo sapiens (human)	Potency	3.1623	1
N-[(S)-[(1S,2R)-1-methyl-2-[(2R)-1-[(5-methyl-2-furanyl)methylamino]-1-oxopropan-2-yl]cyclopropyl]-phenylmethyl]carbamic acid (phenylmethyl) ester	Homo sapiens (human)	Potency	25.1189	1
4-chlorobenzoic acid (5-methyl-2-pyridin-4-yl-4-thiazolyl) ester	Homo sapiens (human)	Potency	19.9526	1
5-amino-2-(3-nitrophenyl)-1-phenyl-2H-pyrrole-3,3,4-tricarbonitrile	Homo sapiens (human)	Potency	39.8107	1
2-amino-6-ethyl-4-(4-methoxyphenyl)-8-[(4-methoxyphenyl)methyl]-4,5-dihydropyrano[3,2-c]pyridine-3-carbonitrile	Homo sapiens (human)	Potency	25.1189	1
sb-224289	Homo sapiens (human)	Potency	12.5893	1
5-methyl-2-(2-phenoxyethyl)-4-phenyl-1,2,4-triazol-3-one	Homo sapiens (human)	Potency	25.1189	1
gw 7647	Homo sapiens (human)	Potency	31.6228	1
4-butyl-3-(6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-3-yl)-1H-1,2,4-triazole-5-thione	Homo sapiens (human)	Potency	12.5893	1
n-(2-(4-(4-chlorophenyl)piperazin-1-yl)ethyl)-3-methoxybenzamide	Homo sapiens (human)	Potency	19.9526	1
1-phenyl-2-[[4-(trifluoromethyl)phenyl]methylthio]imidazole	Homo sapiens (human)	Potency	15.8489	1
2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)thio]propanoic acid methyl ester	Homo sapiens (human)	Potency	39.8107	1
4-[4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-piperidinyl]-3-nitrobenzoic acid methyl ester	Homo sapiens (human)	Potency	3.1623	1
2-hydroxy-2-pentyl-N'-phenylheptanehydrazide	Homo sapiens (human)	Potency	3.1623	1
5-tert-butyl-7-(4-ethyl-1-piperazinyl)-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidine	Homo sapiens (human)	Potency	15.8489	1
5,7-dimethyl-3-phenyldiazenyl-1H-pyrazolo[1,5-a]pyrimidin-2-one	Homo sapiens (human)	Potency	15.8489	1
N-(4-phenylmethoxyphenyl)-3-[4-(phenylmethyl)-1-piperazinyl]propanamide	Homo sapiens (human)	Potency	25.1189	1
1-[4-(2-chlorophenoxy)butyl]imidazole	Homo sapiens (human)	Potency	15.8489	1
4-(2-chlorophenoxy)-5-methoxy-2-(2-pyridinyl)pyrimidine	Homo sapiens (human)	Potency	1.0000	1
rose bengal(2-)	Homo sapiens (human)	Potency	7.9433	1
1-(2,4-dichlorophenyl)-3-[3-(1-imidazolyl)propyl]urea	Homo sapiens (human)	Potency	19.9526	1
rs 17053	Homo sapiens (human)	Potency	6.3096	1
ro 106-9920	Homo sapiens (human)	Potency	2.5119	1
1-(2-fluorophenyl)-3-(N-(phenylmethyl)anilino)thiourea	Homo sapiens (human)	Potency	19.9526	1
suramin sodium	Homo sapiens (human)	Potency	12.5893	1
4-[(3-methyl-5-nitro-4-imidazolyl)amino]phenol	Homo sapiens (human)	Potency	10.0000	1
cp 94253	Homo sapiens (human)	Potency	12.5893	1
4-(1-phenylethyl)-3-(5-propyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione	Homo sapiens (human)	Potency	15.8489	1
2-[[[[[5-[(4-chloro-1-pyrazolyl)methyl]-2-furanyl]-oxomethyl]amino]-sulfanylidenemethyl]amino]-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl ester	Homo sapiens (human)	Potency	15.8489	1
2-[(3-fluorophenyl)-(2-pyridinylamino)methyl]-3-hydroxy-6-(hydroxymethyl)-4-pyranone	Homo sapiens (human)	Potency	7.9433	1
2-[1-[4-(diethylamino)phenyl]-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-N-phenylacetamide	Homo sapiens (human)	Potency	25.1189	1
2-[4-(9H-fluoren-9-yl)-1-piperazinyl]-N-(4-methoxyphenyl)acetamide	Homo sapiens (human)	Potency	39.8107	1
5-methyl-4-[(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)-[1-(1-naphthalenylmethyl)-3-indolyl]methyl]-1,2-dihydropyrazol-3-one	Homo sapiens (human)	Potency	3.9811	1
LSM-26445	Homo sapiens (human)	Potency	19.9526	1
LY-310762	Homo sapiens (human)	Potency	19.9526	1
am 630	Homo sapiens (human)	Potency	6.3096	1
2-methyl-2,6-diphenyl-7-oxa-1-azabicyclo[2.2.1]heptane	Homo sapiens (human)	Potency	3.9811	1
N-(1-dibutoxyphosphoryl-4-oxo-1-naphthalenyl)benzenesulfonamide	Homo sapiens (human)	Potency	6.3096	1
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide	Homo sapiens (human)	Potency	1.2589	1
N-(1H-benzimidazol-2-yl)-3-phenylbutanamide	Homo sapiens (human)	Potency	10.0000	1
1-[(4-fluorophenyl)-oxomethyl]-3-[(5-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)thio]-2-azepanone	Homo sapiens (human)	Potency	31.6228	1
4-(4-propan-2-ylphenyl)-3,4,5,6-tetrahydro-1H-benzo[h]quinazolin-2-one	Homo sapiens (human)	Potency	15.8489	1
rabeprazole(1-)	Homo sapiens (human)	Potency	12.5893	1
4-(4-chlorophenyl)-3-[2-(4-methylphenyl)cyclopropyl]-1H-1,2,4-triazole-5-thione	Homo sapiens (human)	Potency	12.5893	1
2-phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine	Homo sapiens (human)	Potency	25.1189	1
N-(4-tert-butylphenyl)-2-[4-(1-imidazolyl)phenoxy]acetamide	Homo sapiens (human)	Potency	3.1623	1
3,7-dichloro-N-[3-(1-imidazolyl)propyl]-6-methoxy-1-benzothiophene-2-carboxamide	Homo sapiens (human)	Potency	6.3096	1
8-(4-methoxyphenyl)-7-methyl-3-(phenylmethyl)purine-2,6-dione	Homo sapiens (human)	Potency	15.8489	1
4-amino-5-cyano-2-(1-naphthalenylmethylthio)-3-azaspiro[5.5]undeca-2,4-diene-1-carboxamide	Homo sapiens (human)	Potency	39.8107	1
3-methoxy-N-[2-(4-methoxyphenyl)-2-(1-pyrrolidinyl)ethyl]-2-naphthalenecarboxamide	Homo sapiens (human)	Potency	25.1189	1
N-(3,4-dimethylphenyl)-2-[[1-(phenylmethyl)-2-imidazolyl]thio]acetamide	Homo sapiens (human)	Potency	12.5893	1
N-[[[2-(2-naphthalenyloxy)-1-oxopropyl]hydrazo]-sulfanylidenemethyl]-2-furancarboxamide	Homo sapiens (human)	Potency	0.7943	1
N-[3-(2-methylcyclohexyl)-2,4-dihydro-1H-1,3,5-triazin-6-yl]-1,3-benzothiazol-2-amine	Homo sapiens (human)	Potency	12.5893	1
LSM-4833	Homo sapiens (human)	Potency	15.8489	1
3-(3,4-dimethoxyphenyl)-2,5-dimethyl-7-[4-(phenylmethyl)-1-piperazinyl]pyrazolo[1,5-a]pyrimidine	Homo sapiens (human)	Potency	12.5893	1
N'-(4-nitrophenyl)-9-oxo-3-bicyclo[3.3.1]nonanecarbohydrazide	Homo sapiens (human)	Potency	12.5893	1
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid	Homo sapiens (human)	Potency	31.6228	1
1-cyclohexyl-N-(3-methylbutyl)-5-benzimidazolecarboxamide	Homo sapiens (human)	Potency	10.0000	1
(3,5-dichloroanilino)thiourea	Homo sapiens (human)	Potency	2.5119	1
N-[[(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-sulfanylidenemethyl]-2-methylbenzamide	Homo sapiens (human)	Potency	25.1189	1
5,6-dimethyl-1-octyl-4-benzimidazolamine	Homo sapiens (human)	Potency	15.8489	1
sib 1757	Homo sapiens (human)	Potency	31.6228	1
quercetin	Homo sapiens (human)	Potency	14.2191	1
arachidonyltrifluoromethane	Homo sapiens (human)	Potency	19.9526	1
luteolin	Homo sapiens (human)	Potency	12.9244	1
daphnetin	Homo sapiens (human)	Potency	7.9433	1
kaempferol	Homo sapiens (human)	Potency	25.1189	1
alpha-linolenic acid	Homo sapiens (human)	Potency	14.1254	1
harmine	Homo sapiens (human)	Potency	15.8489	1
naringenin chalcone	Homo sapiens (human)	Potency	31.6228	1
pyrantel pamoate	Homo sapiens (human)	Potency	25.1189	1
brompheniramine maleate	Homo sapiens (human)	Potency	15.8489	1
norbixin	Homo sapiens (human)	Potency	31.6228	1
harman	Homo sapiens (human)	Potency	15.8489	1
baicalein	Homo sapiens (human)	Potency	7.9433	1
fisetin	Homo sapiens (human)	Potency	15.8489	1
myricetin	Homo sapiens (human)	Potency	1.5044	1
rhamnetin	Homo sapiens (human)	Potency	12.5893	1
tricetin	Homo sapiens (human)	Potency	12.5893	1
caffeic acid phenethyl ester	Homo sapiens (human)	Potency	10.0000	1
ellagic acid	Homo sapiens (human)	Potency	3.7842	1
ginkgolic acid	Homo sapiens (human)	Potency	25.1189	1
anandamide	Homo sapiens (human)	Potency	0.1413	1
arachidonyl dopamine	Homo sapiens (human)	Potency	8.9125	1
n-oleoyldopamine	Homo sapiens (human)	Potency	2.4906	1
sofalcone	Homo sapiens (human)	Potency	35.4813	1
trimipramine maleate	Homo sapiens (human)	Potency	12.5893	1
flunarizine hydrochloride	Homo sapiens (human)	Potency	10.0000	1
10-octadecenoic acid, (z)-isomer	Homo sapiens (human)	Potency	31.6228	1
n-arachidonylglycine	Homo sapiens (human)	Potency	5.5610	1
perhexiline maleate	Homo sapiens (human)	Potency	31.6228	1
quercetin	Homo sapiens (human)	Potency	10.0000	1
dothiepin	Homo sapiens (human)	Potency	15.8489	1
su 9516	Homo sapiens (human)	Potency	15.8489	1
4-[[[1-[[2-(3-chlorophenyl)-5-methyl-4-oxazolyl]methyl]-3-piperidinyl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl ester	Homo sapiens (human)	Potency	19.9526	1
2-[2-oxo-6-(1-pyrrolidinylsulfonyl)-1,3-benzoxazol-3-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide	Homo sapiens (human)	Potency	31.6228	1
3,4-dihydro-1H-isoquinolin-2-yl-(4-ethyl-5-thieno[3,2-b]pyrrolyl)methanone	Homo sapiens (human)	Potency	25.1189	1
3-(4-chlorophenyl)-1-methyl-N-[3-(1-pyrrolidinyl)propyl]-5-thieno[2,3-c]pyrazolecarboxamide	Homo sapiens (human)	Potency	15.8489	1
[4-(3-methoxyphenyl)-1-piperazinyl]-[2-(1-piperidinyl)-1,3-benzothiazol-6-yl]methanone	Homo sapiens (human)	Potency	15.8489	1
8-(2-chlorophenyl)-3-(4-ethoxyphenyl)-6-oxo-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile	Homo sapiens (human)	Potency	10.0000	1
arachidonylcyclopropylamide	Homo sapiens (human)	Potency	0.8913	1
irl 2500	Homo sapiens (human)	Potency	39.8107	1
l 745870	Homo sapiens (human)	Potency	10.2663	1
n-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl)benzamide	Homo sapiens (human)	Potency	12.5893	1
l803087	Homo sapiens (human)	Potency	22.3872	1
sr 59230a	Homo sapiens (human)	Potency	7.9433	1
cgp 71683 a	Homo sapiens (human)	Potency	28.1838	1
tyrphostin ag 555	Homo sapiens (human)	Potency	31.6228	1
tyrphostin ag-494	Homo sapiens (human)	Potency	31.6228	1
tyrphostin b44	Homo sapiens (human)	Potency	31.6228	1
ag 556	Homo sapiens (human)	Potency	15.8489	1
ag-490	Homo sapiens (human)	Potency	39.8107	1
sulindac sulfide	Homo sapiens (human)	Potency	35.4813	1
6,7-dihydroxyflavone	Homo sapiens (human)	Potency	25.1189	1
7,8-dihydroxy-4-methylcoumarin	Homo sapiens (human)	Potency	10.0000	1
fluvoxamine	Homo sapiens (human)	Potency	12.9244	1
(5R)-3'-phenyl-1-(phenylmethyl)spiro[1,3-diazinane-5,5'-2,4,4a,6-tetrahydro-1H-pyrazino[1,2-a]quinoline]-2,4,6-trione	Homo sapiens (human)	Potency	31.6228	1
3-(1-benzimidazolyl)-6-ethyl-7-hydroxy-1-benzopyran-4-one	Homo sapiens (human)	Potency	3.9811	1
zimeldine	Homo sapiens (human)	Potency	11.0792	1
s-trans,trans-farnesylthiosalicylic acid	Homo sapiens (human)	Potency	31.6228	1
ici 118551	Homo sapiens (human)	Potency	5.0119	1
ethaverine hydrochloride	Homo sapiens (human)	Potency	25.1189	1
fendiline hydrochloride	Homo sapiens (human)	Potency	12.5893	1
methylbenzethonium chloride	Homo sapiens (human)	Potency	3.9811	1
N-(1,3-benzodioxol-5-yl)-2-[(8-methoxy-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]acetamide	Homo sapiens (human)	Potency	25.1189	1
gw-5074	Homo sapiens (human)	Potency	39.8107	1
obtusaquinone	Homo sapiens (human)	Potency	10.0000	1
nf023	Homo sapiens (human)	Potency	12.5893	1
nf 449	Homo sapiens (human)	Potency	0.3981	1
3,5-di-tert-butylchalcone 4'-carboxylic acid	Homo sapiens (human)	Potency	7.9433	1
N-(3,4-dichlorophenyl)-6-(1-imidazolyl)-3-pyridazinamine	Homo sapiens (human)	Potency	15.8489	1
n-(3-(cyclohexylidene-(1h-imidazol-4-ylmethyl))phenyl)ethanesulfonamide	Homo sapiens (human)	Potency	15.8489	1
b 43	Homo sapiens (human)	Potency	7.9433	1
dilazep(2+)	Homo sapiens (human)	Potency	7.9433	1
dihydrexidine	Homo sapiens (human)	Potency	7.9433	1
l 750667	Homo sapiens (human)	Potency	6.3096	1
pd 404182	Homo sapiens (human)	Potency	12.5893	1
sb 222200	Homo sapiens (human)	Potency	39.8107	1
suloctidil	Homo sapiens (human)	Potency	12.5893	1
dibenzheptropine citrate	Homo sapiens (human)	Potency	12.5893	1
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (trans)-(-)-isomer	Homo sapiens (human)	Potency	15.8489	1
5-ia-85380	Homo sapiens (human)	Potency	25.1189	1
ro 25-6981	Homo sapiens (human)	Potency	15.8489	1
aminopurvalanol a	Homo sapiens (human)	Potency	7.9433	1
iem 1460	Homo sapiens (human)	Potency	12.5893	1
Garcinolic acid	Homo sapiens (human)	Potency	25.1189	1
bibx 1382bs	Homo sapiens (human)	Potency	12.5893	1
3-(diphenylmethylene)-1-[4-(4-phenyl-1-piperazinyl)butyl]pyrrolidine-2,5-dione	Homo sapiens (human)	Potency	19.9526	1
N-[2-(3-methoxyphenyl)-4-[(4-methoxyphenyl)methoxy]-6-quinolinyl]-3-pyridinecarboxamide	Homo sapiens (human)	Potency	28.1838	1
sl 327	Homo sapiens (human)	Potency	1.5849	1
3-(1H-benzimidazol-2-yl)-1-[4-(2,4-dimethylphenyl)-1-piperazinyl]-1-propanone	Homo sapiens (human)	Potency	19.9526	1
N-[3-(3,5-dimethyl-1-piperidinyl)propyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide	Homo sapiens (human)	Potency	25.1189	1
LSM-34734	Homo sapiens (human)	Potency	19.9526	1
chlorhexidine	Homo sapiens (human)	Potency	12.5893	1
sgd 301-76	Homo sapiens (human)	Potency	3.9811	1
tabimorelin	Homo sapiens (human)	Potency	19.9526	1
biie 0246	Homo sapiens (human)	Potency	10.0000	1
l 755507	Homo sapiens (human)	Potency	3.1623	1
nnc 26-9100	Homo sapiens (human)	Potency	39.8107	1
gw0742	Homo sapiens (human)	Potency	19.9526	1
NNC 55-0396 (free base)	Homo sapiens (human)	Potency	3.1623	1
sr 11302	Homo sapiens (human)	Potency	28.1838	1
5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1h-indole	Homo sapiens (human)	Potency	28.1838	1
le 135	Homo sapiens (human)	Potency	31.6228	1
methyl arachidonylfluorophosphonate	Homo sapiens (human)	Potency	4.4668	1
2,2,6,6-tetramethylpiperidin-4-yl heptanoate	Homo sapiens (human)	Potency	31.6228	1
tetrabenazine	Homo sapiens (human)	Potency	39.8107	1
n,n'-dibenzhydrylethane-1,2-diamine dihydrochloride	Homo sapiens (human)	Potency	1.0000	1
4-[[[2-(cyclohexylamino)-3,4-dioxo-1-cyclobutenyl]amino]methyl]-N-(4-ethoxyphenyl)benzamide	Homo sapiens (human)	Potency	31.6228	1
N-[5-[2-(5-chloro-2-methylanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]heptanamide	Homo sapiens (human)	Potency	39.8107	1
phenylmercuric acetate	Homo sapiens (human)	Potency	0.3162	1
thimerosal	Homo sapiens (human)	Potency	0.6310	1
nsc 23766	Homo sapiens (human)	Potency	12.5893	1
ro 10-5824	Homo sapiens (human)	Potency	25.1189	1
sodium nitrite	Homo sapiens (human)	Potency	31.6228	1
ethyl 1-benzyl-3-hydroxy-2(5h)-oxopyrrole-4-carboxylate	Homo sapiens (human)	Potency	15.8489	1
N-(1H-benzimidazol-2-yl)-1-ethyl-4-hydroxy-2-oxo-3-quinolinecarboxamide	Homo sapiens (human)	Potency	10.0000	1
rifampin	Homo sapiens (human)	Potency	31.6228	1
clozapine	Homo sapiens (human)	Potency	7.8758	1
suptopin 2	Homo sapiens (human)	Potency	25.1189	1
2-[(2-oxo-3-indolyl)amino]-N-(2-phenylethyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide	Homo sapiens (human)	Potency	25.1189	1
hematein	Homo sapiens (human)	Potency	31.6228	1
norclozapine	Homo sapiens (human)	Potency	12.5893	1
2-[(2-methyl-2,3-dihydroindol-1-yl)methyl]-4-oxo-1H-quinazoline-7-carboxylic acid methyl ester	Homo sapiens (human)	Potency	10.0000	1
N-(2-furanylmethyl)-3-(2-furanylmethylimino)-1-isoindolamine	Homo sapiens (human)	Potency	25.1189	1
ag-879	Homo sapiens (human)	Potency	12.5893	1
1-[4-[[oxo-(7-oxo-4H-isothiazolo[4,3-d]pyrimidin-3-yl)methyl]amino]phenyl]-3-piperidinecarboxylic acid ethyl ester	Homo sapiens (human)	Potency	39.8107	1
2-[(dimethylamino)methyl]-4-spiro[1,6-dihydrobenzo[h]quinazoline-5,1'-cyclohexane]one	Homo sapiens (human)	Potency	15.8489	1
2-(diethylaminomethyl)-4-spiro[1,6-dihydrobenzo[h]quinazoline-5,1'-cyclohexane]one	Homo sapiens (human)	Potency	15.8489	1

Drugs with Inhibition Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
chloroxine	Homo sapiens (human)	IC50	28.0000	1	1
masoprocol	Homo sapiens (human)	IC50	12.3000	2	2
glycyrrhetinic acid	Homo sapiens (human)	IC50	40.0000	1	1
3-hydroxyflavone	Homo sapiens (human)	IC50	100.0000	1	1
ursolic acid	Homo sapiens (human)	IC50	40.0000	1	1
6-hydroxyflavone	Homo sapiens (human)	IC50	100.0000	1	1
beta-amyrin	Homo sapiens (human)	IC50	40.0000	1	1
hederagenin	Homo sapiens (human)	IC50	40.0000	1	1
uvaol	Homo sapiens (human)	IC50	40.0000	1	1
f 1394	Homo sapiens (human)	IC50	0.0320	1	2
3,6-dihydroxyflavone	Homo sapiens (human)	IC50	100.0000	1	1
1-phenyl-2-[[4-(trifluoromethyl)phenyl]methylthio]imidazole	Homo sapiens (human)	IC50	0.3400	1	1
quercetin	Homo sapiens (human)	IC50	100.0000	1	1
15-keto-5,8,11,13-eicosatetraenoic acid	Homo sapiens (human)	IC50	100.0000	1	1
baicalein	Homo sapiens (human)	IC50	51.0929	3	7
fisetin	Homo sapiens (human)	IC50	100.0000	1	1
daidzein	Homo sapiens (human)	IC50	100.0000	1	2
7-hydroxyflavone	Homo sapiens (human)	IC50	100.0000	1	1
5-oxo-6,8,11,14-eicosatetraenoic acid	Homo sapiens (human)	IC50	100.0000	1	1
6,7,4'-trihydroxyisoflavone	Homo sapiens (human)	IC50	80.0000	2	3
7-hydroxyisoflavone	Homo sapiens (human)	IC50	100.0000	1	2
3,7-dihydroxyflavone	Homo sapiens (human)	IC50	100.0000	1	1
4',7,8-trihydroxyisoflavone	Homo sapiens (human)	IC50	0.9000	1	1
13-oxo-9,11-octadecadienoic acid	Homo sapiens (human)	IC50	100.0000	1	1
manzamine a	Homo sapiens (human)	IC50	4.8000	1	1
acetyl-11-ketoboswellic acid	Homo sapiens (human)	IC50	40.0000	1	1
3-o-acetyl-beta-boswellic acid	Homo sapiens (human)	IC50	12.2000	1	1
N-[(5-bromo-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamide	Homo sapiens (human)	IC50	100.0000	1	1
ML355	Homo sapiens (human)	IC50	100.0000	1	1

Drugs with Activation Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
1-phenyl-2-[[4-(trifluoromethyl)phenyl]methylthio]imidazole	Homo sapiens (human)	EC50	0.7500	1	1

Drugs with Other Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
1-phenyl-2-[[4-(trifluoromethyl)phenyl]methylthio]imidazole	Homo sapiens (human)	Kic	0.7000	1	1
1-phenyl-2-[[4-(trifluoromethyl)phenyl]methylthio]imidazole	Homo sapiens (human)	Kiuc	1.2000	1	1

Enables

This protein enables 8 target(s):

Target	Category	Definition
iron ion binding	molecular function	Binding to an iron (Fe) ion. [GOC:ai]
calcium ion binding	molecular function	Binding to a calcium ion (Ca2+). [GOC:ai]
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
lipid binding	molecular function	Binding to a lipid. [GOC:ai]
linoleate 13S-lipoxygenase activity	molecular function	Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate. [EC:1.13.11.12, GOC:lb]
arachidonate 8(S)-lipoxygenase activity	molecular function	Catalysis of the reaction: arachidonate + O2 = (5Z,8S,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate. [GOC:lb, PMID:10625675, RHEA:38675]
arachidonate 15-lipoxygenase activity	molecular function	Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate. [EC:1.13.11.33]
linoleate 9S-lipoxygenase activity	molecular function	Catalysis of the reaction: linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate. [GOC:rph, RHEA:30291]

Located In

This protein is located in 8 target(s):

Target	Category	Definition
nucleus	cellular component	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
cytosol	cellular component	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
cytoskeleton	cellular component	A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. [GOC:mah, PMID:16959967, PMID:27419875]
plasma membrane	cellular component	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
adherens junction	cellular component	A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules. [GOC:aruk, GOC:bc, GOC:mah, ISBN:0198506732, PMID:17854762, PMID:20571587, PMID:21422226, PMID:28096264]
focal adhesion	cellular component	A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ). [GOC:aruk, GOC:bc, ISBN:0124325653, ISBN:0815316208, PMID:10419689, PMID:12191915, PMID:15246682, PMID:1643657, PMID:16805308, PMID:19197329, PMID:23033047, PMID:26923917, PMID:28796323, PMID:8314002]
membrane	cellular component	A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194]
extracellular exosome	cellular component	A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894]

Involved In

This protein is involved in 21 target(s):

Target	Category	Definition
lipid metabolic process	biological process	The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. [GOC:ma]
phospholipid metabolic process	biological process	The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester. [ISBN:0198506732]
apoptotic process	biological process	A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. [GOC:cjm, GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263]
negative regulation of cell population proliferation	biological process	Any process that stops, prevents or reduces the rate or extent of cell proliferation. [GOC:go_curators]
positive regulation of macrophage derived foam cell differentiation	biological process	Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions. [GOC:add, GOC:dph, GOC:tb]
arachidonic acid metabolic process	biological process	The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer. [ISBN:0198506732]
negative regulation of cell migration	biological process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration. [GOC:go_curators]
prostate gland development	biological process	The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. [PMID:11839751]
regulation of epithelial cell differentiation	biological process	Any process that modulates the frequency, rate or extent of epithelial cell differentiation. [GOC:mah]
positive regulation of chemokine production	biological process	Any process that activates or increases the frequency, rate, or extent of chemokine production. [GOC:mah]
positive regulation of peroxisome proliferator activated receptor signaling pathway	biological process	Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. [GOC:bf]
positive regulation of keratinocyte differentiation	biological process	Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation. [GOC:go_curators]
negative regulation of cell cycle	biological process	Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. [GOC:dph, GOC:go_curators, GOC:tb]
negative regulation of growth	biological process	Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism. [GOC:go_curators]
hepoxilin biosynthetic process	biological process	The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology. [GOC:ai]
endocannabinoid signaling pathway	biological process	The series of molecular signals generated as a consequence of an endocannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Endocannabinoids are small molecules derived from arachidonic acid, anandamide (arachidonoylethanolamide) and 2-arachidonoylglycerol. [GOC:bf, GOC:mah, PMID:15550444]
cannabinoid biosynthetic process	biological process	The chemical reactions and pathways resulting in the formation of cannabinoid. [GOC:TermGenie]
lipoxin A4 biosynthetic process	biological process	The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds. [GOC:mw]
linoleic acid metabolic process	biological process	The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. [Wikipedia:Linoleic_Acid]
lipid oxidation	biological process	The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen. [GOC:BHF, GOC:mah]
lipoxygenase pathway	biological process	The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase. [GOC:mah, PMID:17163881]

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