An ATP-binding cassette sub-family C member 3 that is encoded in the genome of human. [PRO:DNx, UniProtKB:O15438]
EC 7.6.2.-;
EC 7.6.2.2;
EC 7.6.2.3;
Canalicular multispecific organic anion transporter 2;
Multi-specific organic anion transporter D;
MOAT-D;
Multidrug resistance-associated protein 3
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| melatonin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pyrazinamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| 1-(3-chlorophenyl)piperazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tacrine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| acetaminophen | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| acetazolamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| albendazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| albuterol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| alprenolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| diatrizoic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| aminoglutethimide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| theophylline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amiodarone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dan 2163 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amitriptyline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amlexanox | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amlodipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amoxapine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amsacrine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| anastrozole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| anthralin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| antipyrine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| aspirin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| astemizole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| atenolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| azathioprine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| baclofen | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| benzbromarone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| benzocaine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bicalutamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bay h 4502 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bisacodyl | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bromopride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bronopol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bumetanide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| busulfan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| caffeine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| verapamil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| carbamazepine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| carmustine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| carprofen | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| carvedilol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| celecoxib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlorambucil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlordiazepoxide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chloroquine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlorpheniramine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlorpromazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlorpropamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlorthalidone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chlorzoxazone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cifenline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ciclopirox | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ciglitazone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cilostazol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cimetidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ciprofibrate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ciprofloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| citalopram | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clioquinol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clobazam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clofazimine | Homo sapiens (human) | IC50 | 21.0000 | 1 | 1 |
| clofibrate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clomiphene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clomipramine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| 4-chloro-N-(2,6-dimethyl-1-piperidinyl)-3-sulfamoylbenzamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dapsone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| desipramine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| diazepam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| diazoxide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dipyridamole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| disopyramide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| disulfiram | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| domperidone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| donepezil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| doxepin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ebastine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| enoxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ethacrynic acid | Homo sapiens (human) | IC50 | 95.9000 | 1 | 1 |
| ethosuximide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| brl 42810 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| 4-biphenylylacetic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| felodipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fenofibrate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fleroxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fluconazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| flucytosine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| flumazenil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fluorescite | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fluorouracil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fluoxetine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| flutamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| furosemide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gemfibrozil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gliclazide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| glimepiride | Homo sapiens (human) | IC50 | 6.3900 | 1 | 1 |
| glipizide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| glyburide | Homo sapiens (human) | IC50 | 33.0000 | 1 | 1 |
| guanfacine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| haloperidol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hydrochlorothiazide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hydroflumethiazide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hydroxyurea | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lidocaine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ifosfamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| imipramine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amrinone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| indapamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| indomethacin | Homo sapiens (human) | IC50 | 66.0000 | 1 | 1 |
| iohexol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| iproniazid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| avapro | Homo sapiens (human) | IC50 | 21.1000 | 1 | 1 |
| isoniazid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| isradipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| itraconazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ketamine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ketanserin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ketoconazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lansoprazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| leflunomide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lofepramine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lomustine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| loratadine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| maprotiline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mebendazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mefenamic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| metformin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| metoclopramide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| metoprolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| metronidazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mexiletine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| minoxidil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mirtazapine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| moclobemide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| acecainide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nadolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nalidixic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nefazodone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nefopam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| neostigmine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nevirapine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nicardipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nifedipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nimesulide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nimodipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nisoldipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nitrazepam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nitrendipine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| norfloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nortriptyline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ofloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| omeprazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ondansetron | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| oxaprozin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| oxybutynin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| papaverine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pemoline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pentamidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pentoxifylline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| perphenazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| phenacetin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pindolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pioglitazone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| piracetam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| piribedil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ono 1078 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pyranoprofen | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| praziquantel | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| prazosin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| primaquine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| primidone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| probenecid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| procainamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| prochlorperazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| procyclidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| promethazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| propafenone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| propranolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ranitidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| riluzole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| risperidone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rofecoxib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sulfadiazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sotalol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| imatinib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vorinostat | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sulfamethoxazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sulfanitran | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sulfasalazine | Homo sapiens (human) | IC50 | 14.6000 | 1 | 1 |
| sulfisoxazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sumatriptan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gatifloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tazarotene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| temozolomide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| terazosin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| terbutaline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| terfenadine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| thiotepa | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tiapride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tilorone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tinidazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tizanidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nikethamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tolbutamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tolnaftate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| trazodone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| triamterene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| trimethoprim | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| troglitazone | Homo sapiens (human) | IC50 | 31.0000 | 1 | 1 |
| thenoyltrifluoroacetone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| undecylenic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| urapidil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| venlafaxine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vigabatrin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pirinixic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ici 204,219 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zaleplon | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zonisamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zopiclone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| prednisolone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| reserpine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| carbon tetrachloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| chloramphenicol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ethinyl estradiol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tubocurarine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| apomorphine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| kanamycin a | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| levodopa | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| colchicine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| triamcinolone diacetate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cytarabine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| medroxyprogesterone acetate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| triamcinolone acetonide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| methylprednisolone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rotenone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| phenformin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| aminophylline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| galantamine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| procarbazine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| betamethasone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| emetine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dimenhydrinate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| 1-naphthylisothiocyanate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| megestrol acetate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| erythromycin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hydroxychloroquine sulfate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| levonorgestrel | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ethambutol hydrochloride | Homo sapiens (human) | IC50 | 88.2000 | 1 | 1 |
| antimycin a | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pregnenolone carbonitrile | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| metylperon | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| stavudine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dicloxacillin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cladribine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| metocurine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| etidronate disodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zalcitabine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| camptothecin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mafenide acetate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| diacerein | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| selegiline hydrochloride, (r)-isomer | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| thiamphenicol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pancuronium bromide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ornidazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| danazol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fludarabine phosphate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| benzonidazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amoxicillin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| timolol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| indoramin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| oxcarbazepine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| carbidopa | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zidovudine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| feprazone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tobramycin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| paclitaxel | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| etoposide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ribavirin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amikacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| diltiazem | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vecuronium bromide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nitazoxanide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| acarbose | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lorcainide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| captopril | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| staurosporine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| foscarnet sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| atracurium besylate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nicorandil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pergolide mesylate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cefadroxil anhydrous | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| talniflumate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fenoldopam mesylate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cefaclor anhydrous | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pefloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cefotetan | Homo sapiens (human) | IC50 | 79.0000 | 1 | 1 |
| lovastatin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| flupirtine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| enoximone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| stepronin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| simvastatin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| idazoxan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| remoxipride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cabergoline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| atomoxetine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| quinapril | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mifepristone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| salmeterol xinafoate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| finasteride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| imiquimod | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sertindole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| adapalene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| aromasil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sparfloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zileuton | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cidofovir anhydrous | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bromfenac | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gemcitabine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| aripiprazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| atorvastatin calcium anhydrous | Homo sapiens (human) | IC50 | 14.2000 | 1 | 1 |
| lamivudine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| duloxetine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| valsartan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zolmitriptan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| adefovir dipivoxil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| emtricitabine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| paroxetine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bupropion hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| trazodone hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| doxazosin mesylate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| efavirenz | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nelfinavir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mevastatin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bupivacaine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| plerixafor | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amprenavir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ticlopidine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| epirubicin hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pazufloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| repaglinide | Homo sapiens (human) | IC50 | 16.7000 | 1 | 1 |
| telmisartan | Homo sapiens (human) | IC50 | 60.0000 | 1 | 1 |
| miconazole nitrate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zoledronic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| artemisinin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| brinzolamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| drospirenone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| artemether | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| uk 68798 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hp 873 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| loxapine succinate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| voriconazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| betamipron | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| aceclofenac | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| doripenem | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rosiglitazone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tamiflu | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bexarotene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| s20098 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| flunisolide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ketorolac tromethamine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clarithromycin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nicotine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gliquidone | Homo sapiens (human) | IC50 | 23.8500 | 1 | 1 |
| lopinavir | Homo sapiens (human) | IC50 | 21.0000 | 1 | 1 |
| moxifloxacin hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fulvestrant | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mizoribine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sr141716 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bosentan anhydrous | Homo sapiens (human) | IC50 | 42.0000 | 1 | 1 |
| racecadotril | Homo sapiens (human) | IC50 | 99.0000 | 1 | 1 |
| tadalafil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| plavix | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| clofarabine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pramipexole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| valdecoxib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mk 0663 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gefitinib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| desloratadine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| methotrexate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sulbactam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| olmesartan medoxomil | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| abiraterone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| febuxostat | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lexapro | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| docetaxel anhydrous | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| levofloxacin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ezetimibe | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cox 189 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| xamoterol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| naproxen | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| telbivudine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| atropine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| etravirine | Homo sapiens (human) | IC50 | 5.1000 | 1 | 1 |
| ramelteon | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| deferasirox | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bms204352 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tbc-11251 | Homo sapiens (human) | IC50 | 45.4000 | 1 | 1 |
| tolvaptan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lenalidomide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lacosamide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vincaleukoblastine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vincristine sulfate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| wortmannin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bortezomib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ritonavir | Homo sapiens (human) | IC50 | 11.1000 | 1 | 1 |
| quinidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| meropenem | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| digitoxin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| saquinavir | Homo sapiens (human) | IC50 | 42.0000 | 1 | 1 |
| perindopril erbumine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| miglitol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rocuronium bromide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| linezolid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pemirolast potassium salt | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| eplerenone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ao 128 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| loteprednol etabonate | Homo sapiens (human) | IC50 | 15.5200 | 1 | 1 |
| fluticasone propionate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tretinoin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tacrolimus | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mupirocin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| zithromax | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| decitabine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| teniposide | Homo sapiens (human) | IC50 | 20.6000 | 1 | 1 |
| valrubicin | Homo sapiens (human) | IC50 | 76.3000 | 1 | 1 |
| melphalan | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| posaconazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rubitecan | Homo sapiens (human) | IC50 | 10.2000 | 1 | 1 |
| arginine vasopressin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| trilostane | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| leuprolide acetate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| propylthiouracil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| levosulpiride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| eszopiclone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| methimazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cinnarizine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sulindac | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| epalrestat | Homo sapiens (human) | IC50 | 45.8000 | 1 | 1 |
| drotaverin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tamoxifen | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fusidic acid | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| valinomycin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hmr 3647 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| latoconazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| maraviroc | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| toremifene citrate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nelarabine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gestodene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| orlistat | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| quinine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| azilect | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dasatinib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sitagliptin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tolcapone | Homo sapiens (human) | IC50 | 85.0000 | 1 | 1 |
| quercetin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| calcitriol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| alprostadil | Homo sapiens (human) | IC50 | 26.9000 | 1 | 1 |
| vitamin d 2 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pulmicort | Homo sapiens (human) | IC50 | 54.5000 | 1 | 1 |
| oxymetholone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| eprosartan | Homo sapiens (human) | IC50 | 6.6500 | 1 | 1 |
| brompheniramine maleate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dexchlorpheniramine maleate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mycophenolate mofetil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| entacapone | Homo sapiens (human) | IC50 | 35.1000 | 1 | 1 |
| l 660,711 | Homo sapiens (human) | IC50 | 9.3000 | 1 | 1 |
| travoprost | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tranilast | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| etretinate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| isotretinoin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ketotifen fumarate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dinoprost tromethamine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rosuvastatin calcium | Homo sapiens (human) | IC50 | 58.3000 | 1 | 1 |
| terbinafine hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cyclosporine | Homo sapiens (human) | IC50 | 11.8158 | 2 | 2 |
| natamycin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| acitretin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| levetiracetam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nalmefene | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| naloxone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| topiramate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| demycarosylturimycin h | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| acipimox | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| atosiban | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bimatoprost | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| latanoprost | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nateglinide | Homo sapiens (human) | IC50 | 104.0000 | 1 | 1 |
| (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid | Homo sapiens (human) | IC50 | 57.0000 | 1 | 1 |
| molsidomine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| butorphanol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cefixime | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lisinopril | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ramipril | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| indinavir sulfate | Homo sapiens (human) | IC50 | 83.0000 | 1 | 1 |
| enalapril maleate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| enalaprilat anhydrous | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| trandolapril | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pregabalin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| alvimopan anhydrous | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| famotidine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cci 15641 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tenofovir disoproxil fumarate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dexbrompheniramine maleate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rifaximin | Homo sapiens (human) | IC50 | 65.0000 | 1 | 1 |
| everolimus | Homo sapiens (human) | IC50 | 84.0000 | 1 | 1 |
| cefpodoxime proxetil | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fluphenazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| nitrofurantoin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| roxithromycin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cefdinir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bisoprolol, fumarate (1:1) salt | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| artesunate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| etoposide phosphate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ciclesonide | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| temsirolimus | Homo sapiens (human) | IC50 | 71.9000 | 1 | 1 |
| dutasteride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| vildagliptin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sgd 301-76 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| fluvoxamine maleate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| thioacetazone | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dexlansoprazole | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| gemifloxacin mesylate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rivaroxaban | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| hki 272 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tofacitinib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pazopanib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| amg 009 | Homo sapiens (human) | IC50 | 1.1000 | 1 | 1 |
| cefotaxime sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| losartan potassium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dactolisib | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rabeprazole sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| bivalirudin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| somatostatin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ly-146032 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| warfarin sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| pravastatin sodium | Homo sapiens (human) | IC50 | 125.0000 | 1 | 1 |
| alendronate sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| sl 80.0750 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mesna | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| piperacillin sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| oxacillin sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| cefazolin sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| azlocillin sodium | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tetracycline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| piroxicam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| roquinimex | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mobic | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| mobiflex | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| isoxicam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| minocycline hydrochloride | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tigecycline | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| lornoxicam | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| entecavir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| acyclovir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rifampin | Homo sapiens (human) | IC50 | 69.0000 | 1 | 1 |
| clozapine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| dacarbazine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| didanosine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ganciclovir | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| valtrex | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| olanzapine | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| raltitrexed | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| allopurinol | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| citrovorum factor | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rifapentine | Homo sapiens (human) | IC50 | 80.9000 | 1 | 1 |
| sildenafil citrate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| aprepitant | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| tegaserod maleate | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| rifabutin | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| cefadroxil anhydrous | Homo sapiens (human) | Km | 2,500.0000 | 1 | 1 |
| 7-hydroxycoumarin glucuronide | Homo sapiens (human) | Km | 187.0000 | 1 | 1 |
This protein enables 11 target(s):
| Target | Category | Definition |
|---|---|---|
| ATP binding | molecular function | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732] |
| ABC-type xenobiotic transporter activity | molecular function | Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out). [EC:7.6.2.2] |
| glucuronoside transmembrane transporter activity | molecular function | Enables the transfer of a glucuronosides from one side of a membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate. [GOC:ai, GOC:mtg_transport, ISBN:0815340729] |
| ABC-type glutathione S-conjugate transporter activity | molecular function | Catalysis of the reaction: ATP + H2O + glutathione S-conjugate(in) -> ADP + phosphate + glutathione S-conjugate(out). [GOC:jl, PMID:1455517, RHEA:19121] |
| ABC-type bile acid transporter activity | molecular function | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O -> bile acid(out) + ADP + phosphate. [RHEA:50048] |
| ATP hydrolysis activity | molecular function | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. [RHEA:13065] |
| ATPase-coupled transmembrane transporter activity | molecular function | Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. [GOC:mtg_transport, ISBN:0815340729] |
| xenobiotic transmembrane transporter activity | molecular function | Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:go_curators, GOC:krc] |
| ATPase-coupled inorganic anion transmembrane transporter activity | molecular function | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + inorganic anion(out) = ADP + phosphate + inorganic anion(in). [GOC:mlg] |
| icosanoid transmembrane transporter activity | molecular function | Enables the transfer of icosanoids from one side of a membrane to the other. [GOC:sl] |
| ABC-type transporter activity | molecular function | Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane. [PMID:26517899] |
This protein is located in 3 target(s):
| Target | Category | Definition |
|---|---|---|
| plasma membrane | cellular component | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363] |
| basal plasma membrane | cellular component | The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. [GOC:go_curators] |
| basolateral plasma membrane | cellular component | The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis. [GOC:go_curators] |
This protein is active in 1 target(s):
| Target | Category | Definition |
|---|---|---|
| membrane | cellular component | A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. [GOC:dos, GOC:mah, ISBN:0815316194] |
This protein is involved in 9 target(s):
| Target | Category | Definition |
|---|---|---|
| xenobiotic metabolic process | biological process | The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:cab2, GOC:krc] |
| xenobiotic transmembrane transport | biological process | The process in which a xenobiotic, a compound foreign to the organim exposed to it, is transported across a membrane. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:ai, GOC:bf, GOC:krc] |
| bile acid and bile salt transport | biological process | The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:dph, GOC:krc, PMID:12663868, PMID:14699511] |
| glucuronoside transport | biological process | The directed movement of glucuronosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate. [GOC:ai] |
| xenobiotic transport | biological process | The directed movement of a xenobiotic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. [GOC:go_curators, GOC:krc] |
| transmembrane transport | biological process | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. [GOC:dph, GOC:jid] |
| leukotriene transport | biological process | The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups. [GOC:mah] |
| monoatomic anion transmembrane transport | biological process | The process in which a monoatomic anion is transported across a membrane. Monatomic anions (also called simple anions) are negatively charged ions consisting of exactly one atom. [GOC:dos, GOC:vw] |
| transport across blood-brain barrier | biological process | The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier. [GOC:aruk, GOC:bc, PMID:29377008] |