nimesulide has been researched along with Sensitivity and Specificity in 19 studies
nimesulide: structure
nimesulide : An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "98 per patient depending on the dosage of diclofenac used." | 5.30 | Economic evaluation of nimesulide versus diclofenac in the treatment of osteoarthritis in Greece. ( Diamantopoulos, E; Ifandi, G; Ignatiades, T; Katostaras, F; Liaropoulos, L; Spinthouri, M, 1998) |
| "To investigate the effect of cervical application of nonselective and selective inhibitors of nitric oxide synthases--N-nitro-L-arginine methyl ester, L-N-iminoethyl-lysine, and aminoguanidine--as well as inhibitors of cyclooxygenases--indomethacin, and nimesulide--on timing of delivery and fetal death and disease in pregnant rats." | 3.71 | The effects of cervical application of inhibitors of inducible nitric oxide synthase, cyclooxygenase-1, and cyclooxygenase-2 on delivery in rats. ( Bukowski, R; Garfield, RE; McKay, L; Saade, GR; Shi, SQ, 2001) |
| " Its use for pharmacokinetic studies has been evaluated." | 2.68 | High-performance thin-layer chromatography for the determination of nimesulide in human plasma, and its use in pharmacokinetic studies. ( Chakravarthy, BK; Gandhi, TP; Modi, IA; Modi, RI; Pandya, KK; Satia, MC, 1997) |
| "Nimesulide is a selective COX-2 inhibitor that is as effective as the classical non-acidic nonsteroidal anti-inflammatory drugs in the relief of various pain and inflammatory conditions, but is better tolerated with lower incidences of adverse effects than other drugs." | 1.38 | Quantification of nimesulide in human plasma by high-performance liquid chromatography with ultraviolet detector (HPLC-UV): application to pharmacokinetic studies in 28 healthy Korean subjects. ( Kang, JS; Kim, DW; Kim, MS; Kim, SH; Kim, SY; Kim, YH; Lee, MH; Park, YS; Yang, SC, 2012) |
| " Results established selectivity and suitability of the method for pharmacokinetic studies of curcumin from C-SLNs." | 1.36 | Pharmacokinetic applicability of a validated liquid chromatography tandem mass spectroscopy method for orally administered curcumin loaded solid lipid nanoparticles to rats. ( Chauhan, AS; Kakkar, V; Kaur, IP; Sahwney, S; Singh, G; Singh, S; Singla, D, 2010) |
| " The method is suitable not only for the estimation of active ingredients in pharmaceutical dosage forms but also in vitro estimations in human plasma." | 1.33 | Development and validation of a reversed-phase liquid chromatographic method for separation and simultaneous determination of COX-2 inhibitors in pharmaceuticals and its application to biological fluids. ( Meena, S; Nagaraju, D; Rao, AR; Rao, RN, 2005) |
| "Two simple and accurate ultraviolet (UV) spectrophotometric methods with better detection range for estimation of nimesulide in pure form and in solid dosage form were developed in the present studies using 50% v/v and 100% v/v acetonitrile as the solvent system." | 1.31 | New Ultraviolet spectrophotometric method for the estimation of nimesulide. ( Chandran, S; Priya, KP; Saggar, S; Saha, RN, 2000) |
| "98 per patient depending on the dosage of diclofenac used." | 1.30 | Economic evaluation of nimesulide versus diclofenac in the treatment of osteoarthritis in Greece. ( Diamantopoulos, E; Ifandi, G; Ignatiades, T; Katostaras, F; Liaropoulos, L; Spinthouri, M, 1998) |
| "Nimesulide was extracted in a single step into dichloromethane." | 1.30 | Rapid and sensitive method for determination of nimesulide in human plasma by high-performance liquid chromatography. ( Khaksa, G; Udupa, N, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 13 (68.42) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Zacharis, CK | 1 |
| Tzanavaras, PD | 2 |
| Notou, M | 1 |
| Zotou, A | 1 |
| Themelis, DG | 2 |
| Kakkar, V | 1 |
| Singh, S | 1 |
| Singla, D | 1 |
| Sahwney, S | 1 |
| Chauhan, AS | 1 |
| Singh, G | 1 |
| Kaur, IP | 1 |
| Kim, MS | 1 |
| Park, YS | 1 |
| Kim, SH | 1 |
| Kim, SY | 1 |
| Lee, MH | 1 |
| Kim, YH | 1 |
| Kim, DW | 1 |
| Yang, SC | 1 |
| Kang, JS | 1 |
| Furlanetto, S | 1 |
| Orlandini, S | 1 |
| Mura, P | 1 |
| Sergent, M | 1 |
| Pinzauti, S | 1 |
| Maltese, A | 1 |
| Maugeri, F | 1 |
| Bucolo, C | 1 |
| Rao, RN | 1 |
| Meena, S | 1 |
| Nagaraju, D | 1 |
| Rao, AR | 1 |
| Majd, S | 1 |
| Mayer, M | 1 |
| Visky, D | 1 |
| Haghedooren, E | 1 |
| Dehouck, P | 1 |
| Kovács, Z | 1 |
| Kóczián, K | 1 |
| Noszál, B | 1 |
| Hoogmartens, J | 1 |
| Adams, E | 1 |
| Wang, C | 1 |
| Shao, X | 1 |
| Liu, Q | 1 |
| Qu, Q | 1 |
| Yang, G | 1 |
| Hu, X | 1 |
| Pandya, KK | 1 |
| Satia, MC | 1 |
| Modi, IA | 1 |
| Modi, RI | 1 |
| Chakravarthy, BK | 1 |
| Gandhi, TP | 1 |
| Carini, M | 1 |
| Aldini, G | 1 |
| Stefani, R | 1 |
| Marinello, C | 1 |
| Facino, RM | 1 |
| Liaropoulos, L | 1 |
| Spinthouri, M | 1 |
| Ignatiades, T | 1 |
| Ifandi, G | 1 |
| Katostaras, F | 1 |
| Diamantopoulos, E | 1 |
| Khaksa, G | 1 |
| Udupa, N | 1 |
| Chandran, S | 1 |
| Saggar, S | 1 |
| Priya, KP | 1 |
| Saha, RN | 1 |
| Ptácek, P | 1 |
| Macek, J | 1 |
| Klíma, J | 1 |
| Bukowski, R | 1 |
| McKay, L | 1 |
| Shi, SQ | 1 |
| Saade, GR | 1 |
| Garfield, RE | 1 |
| Barrientos-Astigarraga, RE | 1 |
| Vannuchi, YB | 1 |
| Sucupira, M | 1 |
| Moreno, RA | 1 |
| Muscará, MN | 1 |
| De Nucci, G | 1 |
2 trials available for nimesulide and Sensitivity and Specificity
| Article | Year |
|---|---|
High-performance thin-layer chromatography for the determination of nimesulide in human plasma, and its use in pharmacokinetic studies.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chrom | 1997 |
Quantification of nimesulide in human plasma by high-performance liquid chromatography/tandem mass spectrometry. Application to bioequivalence studies.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Drug Stability; Ether; Female; Humans; Male | 2001 |
17 other studies available for nimesulide and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Separation and determination of nimesulide related substances for quality control purposes by micellar electrokinetic chromatography.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Boric Acids; Buffers; Calibration; Chromatography, Micellar | 2009 |
Pharmacokinetic applicability of a validated liquid chromatography tandem mass spectroscopy method for orally administered curcumin loaded solid lipid nanoparticles to rats.
Topics: Administration, Oral; Animals; Chromatography, Liquid; Curcumin; Drug Delivery Systems; Least-Square | 2010 |
Quantification of nimesulide in human plasma by high-performance liquid chromatography with ultraviolet detector (HPLC-UV): application to pharmacokinetic studies in 28 healthy Korean subjects.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Asian People | 2012 |
How experimental design can improve the validation process. Studies in pharmaceutical analysis.
Topics: Adsorption; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Electrochemistry | 2003 |
Rapid determination of nimesulide in rabbit aqueous humor by liquid chromatography.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Calibration; Chromatography, High P | 2004 |
Development and validation of a reversed-phase liquid chromatographic method for separation and simultaneous determination of COX-2 inhibitors in pharmaceuticals and its application to biological fluids.
Topics: Butanones; Celecoxib; Chromatography, Liquid; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Lacto | 2005 |
Hydrogel stamping of arrays of supported lipid bilayers with various lipid compositions for the screening of drug-membrane and protein-membrane interactions.
Topics: Annexin A5; Biosensing Techniques; Hydrogel, Polyethylene Glycol Dimethacrylate; Lipid Bilayers; Lip | 2005 |
Facilitated column selection in pharmaceutical analyses using a simple column classification system.
Topics: Aspirin; Chloramphenicol; Chromatography, Liquid; Clindamycin; Dihydrostreptomycin Sulfate; Penicill | 2006 |
Differential pulse voltammetric determination of nimesulide in pharmaceutical formulation and human serum at glassy carbon electrode modified by cysteic acid/CNTs base on electrochemical oxidation of L-cysteine.
Topics: Carbon; Cyclooxygenase 2 Inhibitors; Cysteic Acid; Cysteine; Electrochemistry; Electrodes; Humans; I | 2006 |
Validated high-throughput HPLC assay for nimesulide using a short monolithic column.
Topics: Buffers; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Drug Contamination; Drug S | 2007 |
Mass spectrometric characterization and HPLC determination of the main urinary metabolites of nimesulide in man.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Calibration; Chromatography, High Pressure Liquid; F | 1998 |
Economic evaluation of nimesulide versus diclofenac in the treatment of osteoarthritis in Greece.
Topics: Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Cost-Benefit Analysis; Diclofenac; Greece; | 1998 |
Rapid and sensitive method for determination of nimesulide in human plasma by high-performance liquid chromatography.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liq | 1999 |
New Ultraviolet spectrophotometric method for the estimation of nimesulide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Regression Analysis; Sensitivity | 2000 |
Rapid and simple high-performance liquid chromatographic determination of nimesulide in human plasma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calibration; Chromatography, High Pressure Liquid; Humans; | 2001 |
The effects of cervical application of inhibitors of inducible nitric oxide synthase, cyclooxygenase-1, and cyclooxygenase-2 on delivery in rats.
Topics: Administration, Topical; Animals; Cervical Ripening; Cervix Uteri; Cyclooxygenase Inhibitors; Delive | 2001 |