Page last updated: 2024-08-07 15:56:14
Liver carboxylesterase 1
A protein that is a translation product of the LOC100009551 gene in rabbit. [PRO:DNx, UniProtKB:P12337]
Synonyms
EC 3.1.1.1;
Acyl-coenzyme A:cholesterol acyltransferase
Research
Bioassay Publications (3)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (32)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| diacetyl | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 3 | 8 |
| 6,7-dichloroquinoxaline-2,3-dione | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 2 | 6 |
| benzophenone | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 2 | 6 |
| quinone | Oryctolagus cuniculus (rabbit) | Ki | 71.8579 | 2 | 7 |
| 5-bromoisatin | Oryctolagus cuniculus (rabbit) | Ki | 43.2700 | 1 | 6 |
| isatin | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 1 | 5 |
| chloranil | Oryctolagus cuniculus (rabbit) | Ki | 0.1137 | 2 | 6 |
| benzoin | Oryctolagus cuniculus (rabbit) | Ki | 68.2450 | 2 | 6 |
| dibenzoylmethane | Oryctolagus cuniculus (rabbit) | Ki | 55.6500 | 2 | 6 |
| benzil | Oryctolagus cuniculus (rabbit) | Ki | 20.0670 | 6 | 10 |
| 1,3-cyclohexanedione | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 2 | 7 |
| dibromsalicil | Oryctolagus cuniculus (rabbit) | Ki | 50.0300 | 2 | 6 |
| 1-acetylisatin | Oryctolagus cuniculus (rabbit) | Ki | 87.2000 | 1 | 5 |
| 1-phenyl-1,2-propanedione | Oryctolagus cuniculus (rabbit) | Ki | 31.7000 | 3 | 7 |
| 2,3-pentanedione | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 2 | 6 |
| 5-methylisatin | Oryctolagus cuniculus (rabbit) | Ki | 85.2400 | 1 | 5 |
| 1,2-cyclohexanedione | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 1 | 1 |
| n-methylisatin | Oryctolagus cuniculus (rabbit) | Ki | 68.7160 | 1 | 5 |
| acetylacetone | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 2 | 6 |
| 5-Methoxyisatin | Oryctolagus cuniculus (rabbit) | Ki | 85.3400 | 1 | 5 |
| 3-methyl-1,2-cyclopentanedione | Oryctolagus cuniculus (rabbit) | Ki | 71.9000 | 2 | 6 |
| 4-benzoylbenzoic acid | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 2 | 6 |
| 2-chloranil | Oryctolagus cuniculus (rabbit) | Ki | 2.2092 | 2 | 6 |
| 3,5-di-tert-butyl-1,2-benzoquinone | Oryctolagus cuniculus (rabbit) | Ki | 33.8184 | 2 | 6 |
| 5-Chloro-1H-indole-2,3-dione | Oryctolagus cuniculus (rabbit) | Ki | 44.0980 | 1 | 5 |
| 5-iodoisatin | Oryctolagus cuniculus (rabbit) | Ki | 50.1720 | 1 | 5 |
| 2,2-dimethoxy-2-phenylacetophenone | Oryctolagus cuniculus (rabbit) | Ki | 85.8833 | 2 | 6 |
| anisoin | Oryctolagus cuniculus (rabbit) | Ki | 71.3000 | 2 | 6 |
| hydrobenzoin | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 2 | 6 |
| 5-Fluoroisatin | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 1 | 6 |
| 1-[(3,4-dichlorophenyl)methyl]indole-2,3-dione | Oryctolagus cuniculus (rabbit) | Ki | 12.1926 | 1 | 5 |
| 5-Nitroisatin | Oryctolagus cuniculus (rabbit) | Ki | 81.2860 | 1 | 5 |