diazoxide has been researched along with Sensitivity and Specificity in 7 studies
Diazoxide: A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
diazoxide : A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We examined KATP channel modulation in renal ischemia-reperfusion injury (IRI), using an isolated perfused rat kidney (IPRK) model, in control, IRI, IRI+200 microM diazoxide (a KATP opener), IRI + 10 microM glibenclamide (a KATP blocker) and IRI + 200 microM diazoxide + 10 microM glibenclamide groups." | 3.72 | ATP-dependent K+ channels in renal ischemia reperfusion injury. ( Endre, ZH; Gobé, GC; Rahgozar, M; Willgoss, DA, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Anastacio, MM | 1 |
| Kanter, EM | 1 |
| Makepeace, C | 1 |
| Keith, AD | 1 |
| Zhang, H | 1 |
| Schuessler, RB | 1 |
| Nichols, CG | 1 |
| Lawton, JS | 1 |
| Griesemer, D | 1 |
| Zawar, C | 1 |
| Neumcke, B | 1 |
| Rahgozar, M | 1 |
| Willgoss, DA | 1 |
| Gobé, GC | 1 |
| Endre, ZH | 1 |
| Hsieh, YJ | 1 |
| Wakiyama, H | 1 |
| Levitsky, S | 2 |
| McCully, JD | 2 |
| Lorrain, J | 1 |
| Angel, I | 1 |
| Eon, MT | 1 |
| Oblin, A | 1 |
| Langer, SZ | 1 |
| Toyoda, Y | 1 |
7 other studies available for diazoxide and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Cardioprotective mechanism of diazoxide involves the inhibition of succinate dehydrogenase.
Topics: Animals; Cardiotonic Agents; Cell Size; Cells, Cultured; Diazoxide; Mice; Mice, Inbred C57BL; Mitoch | 2013 |
Cell-type specific depression of neuronal excitability in rat hippocampus by activation of ATP-sensitive potassium channels.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Diazoxide; Hippocampus; In Vitro Techniques; Int | 2002 |
ATP-dependent K+ channels in renal ischemia reperfusion injury.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Cromakalim; Diazoxide; Disease Models, Animal; | 2003 |
Cardioplegia and diazoxide modulate STAT3 activation and DNA binding.
Topics: Animals; Apoptosis; Binding Sites; Blotting, Western; Cardioplegic Solutions; Diazoxide; Disease Mod | 2007 |
Inhibition of insulin release induced by galanin in the dog is not exclusively mediated by activation of ATP-sensitive K+ channels.
Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Diazoxide; Dioxa | 1993 |
Opening of mitochondrial ATP-sensitive potassium channels enhances cardioplegic protection.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Cardioplegic Solutions; Diazoxide; Disease Mo | 2001 |