Compounds > carbenoxolone sodium
Page last updated: 2024-09-23

carbenoxolone sodium

Description

Carbenoxolone: An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID636402
CHEMBL ID1697717
CHEBI ID31351
SCHEMBL ID57233
MeSH IDM0003343

Synonyms (71)

Synonym
bioplex
yp-003
vampex
biogastrone
3-beta-hydroxy-11-oxoolean-12-en-30-oic acid hydrogen succinate, disodium salt
disodium glycyrrhetinyl succina
carbenoxolon-dinatrium
olean-12-en-29-oic acid, 3-(3-carboxy-1-oxopropoxy)-11-oxo-, disodium salt, (3-beta,20-beta)-
berkobiogastrone
18-beta-glycyrrhetinic acid hydrogen succinate, disodium salt
gastrausil
sodium 3-beta-hydroxy-11-oxo-12-oleanen-30-oate sodium succinate
einecs 231-044-0
bioral
ulcus-tablinen
terulcon tabletten
carbenoxolone sodium [usan:jan]
3-o-(beta-carboxypropionyl)-11-oxo-18-beta-olean-12-en-30-oic acid, disodium salt
sanodin
glycyrrhetinic acid hydrogen succinate, disodium salt
olean-12-en-29-oic acid, 3-(3-carboxy-1-oxopropoxy)-11-oxo, disodium salt, (3beta,20beta)-
sodium carbenoxolone
3beta-hydroxy-11-oxoolean-12-en-30-oic acid hydrogen succinate disodium salt
carbenoxolon dinatrium
carbenoxolone, disodium salt
neogel
duogastrone
olean-12-en-30-oic acid, 3-beta-hydroxy-11-oxo-, hydrogen succinate, disodium salt
PRESTWICK_19
carbenoxolone sodium
carbenoxolone disodium salt
carbenoxolone
carbenoxolone sodium (jan/usan)
D01899
HMS1570H15
bdbm50005105
CHEMBL1697717
disodium succinoyl glycyrrhetinate
nsc-758146
HMS2097H15
dtxsid7045572 ,
dtxcid5025572
tox21_110769
AKOS016036367
f1mp7242z5 ,
nsc 758146
unii-f1mp7242z5
3beta-hydroxy-11-oxoolean-12-en-30-oic acid 3-hemisuccinate
olean-12-en-29-oic acid, 3-(3-carboxy-1-oxopropoxy)-11-oxo, disodium salt, (3.beta.,20.beta.)-
carbenoxolone sodium [usan]
carbenoxolone disodium salt [mi]
disodium 3-succinyloxy-.beta.-glycyrrhetinate
olean-12-en-29-oic acid, 3-(3-carboxy-1-oxopropoxy)-11-oxo-, sodium salt (1:2), (3.beta.,20.beta.)-
carbenoxolone sodium [jan]
carbenoxolone sodium [who-dd]
disodium succinoyl glycyrrhetinate [inci]
20.beta.-olean-12-en-29-oic acid, 3(.beta.)-(3-carboxy-1-oxopropoxy)-11-oxo-, disodium salt
carbenoxolone sodium [mart.]
CCG-220837
SCHEMBL57233
NCGC00179431-03
tox21_110769_1
(3?,20?)-3-(3-carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic acid disodium
AKOS024457425
mfcd03840711
yp003
3ss-hydroxy-11-oxoolean-12-en-30-oic acid 3-hemisuccinate
CHEBI:31351
HMS3714H15
Q27277518
disodium;(2s,4as,6ar,6as,6br,8ar,10s,12as,14br)-10-(3-carboxylatopropanoyloxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1h-picene-2-carboxylate

Drug Classes (1)

ClassDescription
triterpenoidAny terpenoid derived from a triterpene. The term includes compounds in which the C30 skeleton of the parent triterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (14)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
RAR-related orphan receptor gammaMus musculus (house mouse)Potency31.67040.006038.004119,952.5996AID1159521; AID1159523
GLI family zinc finger 3Homo sapiens (human)Potency7.49780.000714.592883.7951AID1259369
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency38.90180.01237.983543.2770AID1645841
retinoid X nuclear receptor alphaHomo sapiens (human)Potency26.83250.000817.505159.3239AID1159527
farnesoid X nuclear receptorHomo sapiens (human)Potency18.59560.375827.485161.6524AID743217; AID743220
estrogen nuclear receptor alphaHomo sapiens (human)Potency11.45540.000229.305416,493.5996AID743075
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency29.84700.001024.504861.6448AID743212
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency18.83220.001019.414170.9645AID743191
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency19.39860.023723.228263.5986AID743222; AID743223
activating transcription factor 6Homo sapiens (human)Potency30.10650.143427.612159.8106AID1159516
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency24.62300.057821.109761.2679AID1159526; AID1159528
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency21.37670.000627.21521,122.0200AID743202; AID743219
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)IC50 (µMol)1.90550.10472.71957.0795AID977603
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)Ki1.48000.08002.46889.8000AID977604
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)IC50 (µMol)1.94980.05002.37979.7000AID977600
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)Ki1.07000.04401.36305.0000AID977601
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (9)

Processvia Protein(s)Taxonomy
xenobiotic metabolic processSolute carrier organic anion transporter family member 1B3Homo sapiens (human)
monoatomic ion transportSolute carrier organic anion transporter family member 1B3Homo sapiens (human)
organic anion transportSolute carrier organic anion transporter family member 1B3Homo sapiens (human)
bile acid and bile salt transportSolute carrier organic anion transporter family member 1B3Homo sapiens (human)
heme catabolic processSolute carrier organic anion transporter family member 1B3Homo sapiens (human)
sodium-independent organic anion transportSolute carrier organic anion transporter family member 1B3Homo sapiens (human)
transmembrane transportSolute carrier organic anion transporter family member 1B3Homo sapiens (human)
xenobiotic metabolic processSolute carrier organic anion transporter family member 1B1Homo sapiens (human)
monoatomic ion transportSolute carrier organic anion transporter family member 1B1Homo sapiens (human)
organic anion transportSolute carrier organic anion transporter family member 1B1Homo sapiens (human)
bile acid and bile salt transportSolute carrier organic anion transporter family member 1B1Homo sapiens (human)
prostaglandin transportSolute carrier organic anion transporter family member 1B1Homo sapiens (human)
heme catabolic processSolute carrier organic anion transporter family member 1B1Homo sapiens (human)
sodium-independent organic anion transportSolute carrier organic anion transporter family member 1B1Homo sapiens (human)
transmembrane transportSolute carrier organic anion transporter family member 1B1Homo sapiens (human)
thyroid hormone transportSolute carrier organic anion transporter family member 1B1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (6)

Processvia Protein(s)Taxonomy
serine-type endopeptidase inhibitor activitySolute carrier organic anion transporter family member 1B3Homo sapiens (human)
organic anion transmembrane transporter activitySolute carrier organic anion transporter family member 1B3Homo sapiens (human)
bile acid transmembrane transporter activitySolute carrier organic anion transporter family member 1B3Homo sapiens (human)
sodium-independent organic anion transmembrane transporter activitySolute carrier organic anion transporter family member 1B3Homo sapiens (human)
organic anion transmembrane transporter activitySolute carrier organic anion transporter family member 1B1Homo sapiens (human)
bile acid transmembrane transporter activitySolute carrier organic anion transporter family member 1B1Homo sapiens (human)
prostaglandin transmembrane transporter activitySolute carrier organic anion transporter family member 1B1Homo sapiens (human)
sodium-independent organic anion transmembrane transporter activitySolute carrier organic anion transporter family member 1B1Homo sapiens (human)
thyroid hormone transmembrane transporter activitySolute carrier organic anion transporter family member 1B1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (4)

Processvia Protein(s)Taxonomy
plasma membraneSolute carrier organic anion transporter family member 1B3Homo sapiens (human)
basal plasma membraneSolute carrier organic anion transporter family member 1B3Homo sapiens (human)
basolateral plasma membraneSolute carrier organic anion transporter family member 1B3Homo sapiens (human)
plasma membraneSolute carrier organic anion transporter family member 1B1Homo sapiens (human)
basal plasma membraneSolute carrier organic anion transporter family member 1B1Homo sapiens (human)
membraneSolute carrier organic anion transporter family member 1B1Homo sapiens (human)
basolateral plasma membraneSolute carrier organic anion transporter family member 1B1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (44)

Assay IDTitleYearJournalArticle
AID1347425Rhodamine-PBP qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1)2019The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
AID1296008Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening2020SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1347098qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347103qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347407qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Pharmaceutical Collection2020ACS chemical biology, 07-17, Volume: 15, Issue:7
High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID1347096qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID1347090qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1508630Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay2021Cell reports, 04-27, Volume: 35, Issue:4
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
AID1347106qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347094qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347108qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347093qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID1347104qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347097qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347089qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347100qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347091qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347101qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347105qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347424RapidFire Mass Spectrometry qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1)2019The Journal of biological chemistry, 11-15, Volume: 294, Issue:46
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
AID1347092qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347099qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347154Primary screen GU AMC qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347095qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347107qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347102qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells2018Oncotarget, Jan-12, Volume: 9, Issue:4
Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing.
AID1346986P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1346987P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID977604Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID588210Human drug-induced liver injury (DILI) modelling dataset from Ekins et al2010Drug metabolism and disposition: the biological fate of chemicals, Dec, Volume: 38, Issue:12
A predictive ligand-based Bayesian model for human drug-induced liver injury.
AID977603pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID977600pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID977602Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID625295Drug Induced Liver Injury Prediction System (DILIps) validation dataset; compound DILI positive/negative as observed in Pfizer data2011PLoS computational biology, Dec, Volume: 7, Issue:12
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
AID977599Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID977601Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells2013Molecular pharmacology, Jun, Volume: 83, Issue:6
Structure-based identification of OATP1B1/3 inhibitors.
AID588209Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset2010Chemical research in toxicology, Jul-19, Volume: 23, Issue:7
Developing structure-activity relationships for the prediction of hepatotoxicity.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (1,051)

TimeframeStudies, This Drug (%)All Drugs %
pre-1990313 (29.78)18.7374
1990's124 (11.80)18.2507
2000's269 (25.59)29.6817
2010's295 (28.07)24.3611
2020's50 (4.76)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials79 (7.29%)5.53%
Reviews62 (5.72%)6.00%
Case Studies31 (2.86%)4.05%
Observational0 (0.00%)0.25%
Other912 (84.13%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
ethylene dichloride[no description available]medium20chloroethaneshepatotoxic agent;
mutagen;
non-polar solvent
ethylene glycol[no description available]medium20ethanediol;
glycol		metabolite;
mouse metabolite;
solvent;
toxin
aminocaproic acid[no description available]medium20amino acid zwitterion;
epsilon-amino acid;
omega-amino fatty acid		antifibrinolytic drug;
hematologic agent;
metabolite
hexachlorocyclohexane[no description available]medium20chlorocyclohexane
inositol[no description available]medium20cyclitol;
hexol
melatonin[no description available]medium20acetamides;
tryptamines		anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger
niacin[no description available]medium20pyridine alkaloid;
pyridinemonocarboxylic acid;
vitamin B3		antidote;
antilipemic drug;
EC 3.5.1.19 (nicotinamidase) inhibitor;
Escherichia coli metabolite;
human urinary metabolite;
metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent
pyrazinamide[no description available]medium20monocarboxylic acid amide;
N-acylammonia;
pyrazines		antitubercular agent;
prodrug
pyridoxine[no description available]medium20hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6		cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
thiamine[no description available]medium20primary alcohol;
vitamin B1		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
2,4-dinitrophenol[no description available]medium20dinitrophenolallergen;
antiseptic drug;
bacterial xenobiotic metabolite;
geroprotector;
oxidative phosphorylation inhibitor
3-methylcholanthrene[no description available]medium10ortho- and peri-fused polycyclic arenearyl hydrocarbon receptor agonist;
carcinogenic agent
phenytoin[no description available]medium50imidazolidine-2,4-dioneanticonvulsant;
drug allergen;
sodium channel blocker;
teratogenic agent
tacrine[no description available]medium20acridines;
aromatic amine		EC 3.1.1.7 (acetylcholinesterase) inhibitor
acetaminophen[no description available]medium30acetamides;
phenols		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
cyclooxygenase 3 inhibitor;
environmental contaminant;
ferroptosis inducer;
geroprotector;
hepatotoxic agent;
human blood serum metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
acetazolamide[no description available]medium50monocarboxylic acid amide;
sulfonamide;
thiadiazoles		anticonvulsant;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
acetohexamide[no description available]medium20acetophenones;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue
albendazole[no description available]medium20aryl sulfide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		anthelminthic drug;
microtubule-destabilising agent;
tubulin modulator
aminoglutethimide[no description available]medium20dicarboximide;
piperidones;
substituted aniline		adrenergic agent;
anticonvulsant;
antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor
theophylline[no description available]medium20dimethylxanthineadenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent
amiodarone[no description available]medium201-benzofurans;
aromatic ketone;
organoiodine compound;
tertiary amino compound		cardiovascular drug
amoxapine[no description available]medium20dibenzooxazepineadrenergic uptake inhibitor;
antidepressant;
dopaminergic antagonist;
geroprotector;
serotonin uptake inhibitor
astemizole[no description available]medium20benzimidazoles;
piperidines		anti-allergic agent;
anticoronaviral agent;
H1-receptor antagonist
atenolol[no description available]medium20ethanolamines;
monocarboxylic acid amide;
propanolamine		anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
sympatholytic agent;
xenobiotic
azathioprine[no description available]medium20aryl sulfide;
C-nitro compound;
imidazoles;
thiopurine		antimetabolite;
antineoplastic agent;
carcinogenic agent;
DNA synthesis inhibitor;
hepatotoxic agent;
immunosuppressive agent;
prodrug
benzbromarone[no description available]medium201-benzofurans;
aromatic ketone		uricosuric drug
bicalutamide[no description available]medium20(trifluoromethyl)benzenes;
monocarboxylic acid amide;
monofluorobenzenes;
nitrile;
sulfone;
tertiary alcohol
bithionol[no description available]medium20aryl sulfide;
bridged diphenyl antifungal drug;
bridged diphenyl fungicide;
dichlorobenzene;
organochlorine pesticide;
polyphenol		antifungal agrochemical;
antiplatyhelmintic drug
bumetanide[no description available]medium30amino acid;
benzoic acids;
sulfonamide		diuretic;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor
bupivacaine[no description available]medium20aromatic amide;
piperidinecarboxamide;
tertiary amino compound
buspirone[no description available]medium20azaspiro compound;
N-alkylpiperazine;
N-arylpiperazine;
organic heteropolycyclic compound;
piperidones;
pyrimidines		anxiolytic drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
sedative;
serotonergic agonist
busulfan[no description available]medium20methanesulfonate esteralkylating agent;
antineoplastic agent;
carcinogenic agent;
insect sterilant;
teratogenic agent
caffeine[no description available]medium30purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic
candesartan[no description available]medium20benzimidazolecarboxylic acid;
biphenylyltetrazole		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
carbamazepine[no description available]medium40dibenzoazepine;
ureas		analgesic;
anticonvulsant;
antimanic drug;
drug allergen;
EC 3.5.1.98 (histone deacetylase) inhibitor;
environmental contaminant;
glutamate transporter activator;
mitogen;
non-narcotic analgesic;
sodium channel blocker;
xenobiotic
chlorpromazine[no description available]medium40organochlorine compound;
phenothiazines;
tertiary amine		anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug
chlorpropamide[no description available]medium40monochlorobenzenes;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue
chlorzoxazone[no description available]medium201,3-benzoxazoles;
heteroaryl hydroxy compound;
organochlorine compound		muscle relaxant;
sedative
ciclopirox[no description available]medium20cyclic hydroxamic acid;
hydroxypyridone antifungal drug;
pyridone		antibacterial agent;
antiseborrheic
ciglitazone[no description available]medium20aromatic ether;
thiazolidinone		antineoplastic agent;
insulin-sensitizing drug
cimetidine[no description available]medium910aliphatic sulfide;
guanidines;
imidazoles;
nitrile		adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
cimetidine[no description available]medium9117aliphatic sulfide;
guanidines;
imidazoles;
nitrile		adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
ciprofibrate[no description available]medium20cyclopropanes;
monocarboxylic acid;
organochlorine compound		antilipemic drug
cisapride[no description available]medium20benzamides
citalopram[no description available]medium202-benzofurans;
cyclic ether;
nitrile;
organofluorine compound;
tertiary amino compound
clofibrate[no description available]medium20aromatic ether;
ethyl ester;
monochlorobenzenes		anticholesteremic drug;
antilipemic drug;
geroprotector;
PPARalpha agonist
clomipramine[no description available]medium20dibenzoazepineanticoronaviral agent;
antidepressant;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
serotonergic antagonist;
serotonergic drug;
serotonin uptake inhibitor
clotrimazole[no description available]medium40conazole antifungal drug;
imidazole antifungal drug;
imidazoles;
monochlorobenzenes		antiinfective agent;
environmental contaminant;
xenobiotic
cromolyn[no description available]medium20chromones;
dicarboxylic acid		anti-asthmatic drug;
calcium channel blocker
dapsone[no description available]medium20substituted aniline;
sulfone		anti-inflammatory drug;
antiinfective agent;
antimalarial;
leprostatic drug
desipramine[no description available]medium20dibenzoazepine;
secondary amino compound		adrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
cholinergic antagonist;
drug allergen;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
serotonin uptake inhibitor
diclofenac[no description available]medium30amino acid;
aromatic amine;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
diethylcarbamazine[no description available]medium20N-carbamoylpiperazine;
N-methylpiperazine
diflunisal[no description available]medium20monohydroxybenzoic acid;
organofluorine compound		non-narcotic analgesic;
non-steroidal anti-inflammatory drug
dimercaprol[no description available]medium20dithiol;
primary alcohol		chelator
dipyridamole[no description available]medium20piperidines;
pyrimidopyrimidine;
tertiary amino compound;
tetrol		adenosine phosphodiesterase inhibitor;
EC 3.5.4.4 (adenosine deaminase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent
valproic acid[no description available]medium40branched-chain fatty acid;
branched-chain saturated fatty acid		anticonvulsant;
antimanic drug;
EC 3.5.1.98 (histone deacetylase) inhibitor;
GABA agent;
neuroprotective agent;
psychotropic drug;
teratogenic agent
donepezil[no description available]medium20aromatic ether;
indanones;
piperidines;
racemate		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
nootropic agent
ethosuximide[no description available]medium20dicarboximide;
pyrrolidinone		anticonvulsant;
geroprotector;
T-type calcium channel blocker
carbonyl cyanide p-trifluoromethoxyphenylhydrazone[no description available]medium20aromatic ether;
hydrazone;
nitrile;
organofluorine compound		ATP synthase inhibitor;
geroprotector;
ionophore
felbamate[no description available]medium20carbamate esteranticonvulsant;
neuroprotective agent
fenofibrate[no description available]medium20aromatic ether;
chlorobenzophenone;
isopropyl ester;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
fexofenadine[no description available]medium20piperidines;
tertiary amine		anti-allergic agent;
H1-receptor antagonist
fipexide[no description available]medium20benzodioxoles
fluconazole[no description available]medium20conazole antifungal drug;
difluorobenzene;
tertiary alcohol;
triazole antifungal drug		environmental contaminant;
P450 inhibitor;
xenobiotic
flucytosine[no description available]medium20aminopyrimidine;
nucleoside analogue;
organofluorine compound;
pyrimidine antifungal drug;
pyrimidone		prodrug
flufenamic acid[no description available]medium150aromatic amino acid;
organofluorine compound		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
flumazenil[no description available]medium20ethyl ester;
imidazobenzodiazepine;
organofluorine compound		antidote to benzodiazepine poisoning;
GABA antagonist
fluorouracil[no description available]medium20nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
fluoxetine[no description available]medium30(trifluoromethyl)benzenes;
aromatic ether;
secondary amino compound
flurbiprofen[no description available]medium20fluorobiphenyl;
monocarboxylic acid		antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
fluspirilene[no description available]medium20diarylmethane
flutamide[no description available]medium20(trifluoromethyl)benzenes;
monocarboxylic acid amide		androgen antagonist;
antineoplastic agent
foscarnet[no description available]medium20carboxylic acid;
one-carbon compound;
phosphonic acids		antiviral drug;
geroprotector;
HIV-1 reverse transcriptase inhibitor;
sodium-dependent Pi-transporter inhibitor
furosemide[no description available]medium40chlorobenzoic acid;
furans;
sulfonamide		environmental contaminant;
loop diuretic;
xenobiotic
gabapentin[no description available]medium40gamma-amino acidanticonvulsant;
calcium channel blocker;
environmental contaminant;
xenobiotic
gemfibrozil[no description available]medium20aromatic etherantilipemic drug
glafenine[no description available]medium20aminoquinoline;
carboxylic ester;
glycol;
organochlorine compound;
secondary amino compound		inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
gliclazide[no description available]medium20N-sulfonylureahypoglycemic agent;
insulin secretagogue;
radical scavenger
glimepiride[no description available]medium20sulfonamide
glutethimide[no description available]medium20piperidines
hexachlorophene[no description available]medium20bridged diphenyl fungicide;
polyphenol;
trichlorobenzene		acaricide;
antibacterial agent;
antifungal agrochemical;
antiseptic drug
hycanthone[no description available]medium20thioxanthenesmutagen;
schistosomicide drug
hydrochlorothiazide[no description available]medium30benzothiadiazine;
organochlorine compound;
sulfonamide		antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
hydroxyurea[no description available]medium20one-carbon compound;
ureas		antimetabolite;
antimitotic;
antineoplastic agent;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
genotoxin;
immunomodulator;
radical scavenger;
teratogenic agent
ibuprofen[no description available]medium30monocarboxylic acidantipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic
phenelzine[no description available]medium20primary amine
lidocaine[no description available]medium30benzenes;
monocarboxylic acid amide;
tertiary amino compound		anti-arrhythmia drug;
drug allergen;
environmental contaminant;
local anaesthetic;
xenobiotic
ifosfamide[no description available]medium20ifosfamidesalkylating agent;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
xenobiotic
amrinone[no description available]medium20bipyridinesEC 3.1.4.* (phosphoric diester hydrolase) inhibitor
indomethacin[no description available]medium250aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole		analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic
iproniazid[no description available]medium20carbohydrazide;
pyridines
avapro[no description available]medium20azaspiro compound;
biphenylyltetrazole		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
isocarboxazid[no description available]medium20benzenes
isoniazid[no description available]medium20carbohydrazideantitubercular agent;
drug allergen
ketoconazole[no description available]medium20dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine
ketoprofen[no description available]medium20benzophenones;
oxo monocarboxylic acid		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
ketotifen[no description available]medium20cyclic ketone;
olefinic compound;
organic heterotricyclic compound;
organosulfur heterocyclic compound;
piperidines;
tertiary amino compound		anti-asthmatic drug;
H1-receptor antagonist
labetalol[no description available]medium20benzamides;
benzenes;
phenols;
primary carboxamide;
salicylamides;
secondary alcohol;
secondary amino compound
leflunomide[no description available]medium20(trifluoromethyl)benzenes;
isoxazoles;
monocarboxylic acid amide		antineoplastic agent;
antiparasitic agent;
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
hepatotoxic agent;
immunosuppressive agent;
non-steroidal anti-inflammatory drug;
prodrug;
pyrimidine synthesis inhibitor;
tyrosine kinase inhibitor
losartan[no description available]medium30biphenylyltetrazole;
imidazoles		angiotensin receptor antagonist;
anti-arrhythmia drug;
antihypertensive agent;
endothelin receptor antagonist
maprotiline[no description available]medium20anthracenes
mebendazole[no description available]medium20aromatic ketone;
benzimidazoles;
carbamate ester		antinematodal drug;
microtubule-destabilising agent;
tubulin modulator
meclofenamate sodium anhydrous[no description available]medium20organic sodium salt
mefenamic acid[no description available]medium30aminobenzoic acid;
secondary amino compound		analgesic;
antipyretic;
antirheumatic drug;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic
memantine[no description available]medium20adamantanes;
primary aliphatic amine		antidepressant;
antiparkinson drug;
dopaminergic agent;
neuroprotective agent;
NMDA receptor antagonist
vitamin k 3[no description available]medium201,4-naphthoquinones;
vitamin K		angiogenesis inhibitor;
antineoplastic agent;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
human urinary metabolite;
nutraceutical
meprobamate[no description available]medium20organic molecular entity
metformin[no description available]medium20guanidinesenvironmental contaminant;
geroprotector;
hypoglycemic agent;
xenobiotic
methapyrilene[no description available]medium20ethylenediamine derivativeanti-allergic agent;
carcinogenic agent;
H1-receptor antagonist;
sedative
nocodazole[no description available]medium20aromatic ketone;
benzimidazoles;
carbamate ester;
thiophenes		antimitotic;
antineoplastic agent;
microtubule-destabilising agent;
tubulin modulator
methylphenidate[no description available]medium20beta-amino acid ester;
methyl ester;
piperidines
metolazone[no description available]medium20organochlorine compound;
quinazolines;
sulfonamide		antihypertensive agent;
diuretic;
ion transport inhibitor
metronidazole[no description available]medium20C-nitro compound;
imidazoles;
primary alcohol		antiamoebic agent;
antibacterial drug;
antimicrobial agent;
antiparasitic agent;
antitrichomonal drug;
environmental contaminant;
prodrug;
radiosensitizing agent;
xenobiotic
mianserin[no description available]medium20dibenzoazepineadrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
H1-receptor antagonist;
histamine agonist;
sedative;
serotonergic antagonist
miconazole[no description available]medium20dichlorobenzene;
ether;
imidazoles
nalidixic acid[no description available]medium201,8-naphthyridine derivative;
monocarboxylic acid;
quinolone antibiotic		antibacterial drug;
antimicrobial agent;
DNA synthesis inhibitor
nefazodone[no description available]medium20aromatic ether;
monochlorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
triazoles		alpha-adrenergic antagonist;
analgesic;
antidepressant;
serotonergic antagonist;
serotonin uptake inhibitor
nifedipine[no description available]medium40C-nitro compound;
dihydropyridine;
methyl ester		calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent
nimesulide[no description available]medium20aromatic ether;
C-nitro compound;
sulfonamide		cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
nimodipine[no description available]medium202-methoxyethyl ester;
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
isopropyl ester		antihypertensive agent;
calcium channel blocker;
cardiovascular drug;
vasodilator agent
nisoldipine[no description available]medium20C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
methyl ester
nomifensine[no description available]medium20isoquinolinesdopamine uptake inhibitor
oxaprozin[no description available]medium201,3-oxazoles;
monocarboxylic acid		analgesic;
non-steroidal anti-inflammatory drug
oxibendazole[no description available]medium20benzimidazoles;
carbamate ester
aminosalicylic acid[no description available]medium20aminobenzoic acid;
phenols		antitubercular agent
pamidronate[no description available]medium20phosphonoacetic acid
4-dichlorobenzene[no description available]medium20dichlorobenzeneinsecticide
pargyline[no description available]medium20aromatic amine
pemoline[no description available]medium201,3-oxazolescentral nervous system stimulant
perhexiline[no description available]medium20piperidinescardiovascular drug
phenacetin[no description available]medium30acetamides;
aromatic ether		cyclooxygenase 3 inhibitor;
non-narcotic analgesic;
peripheral nervous system drug
phenylbutazone[no description available]medium50pyrazolidinesantirheumatic drug;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug
pinacidil[no description available]medium30pyridines
pindolol[no description available]medium20indoles;
secondary amine		antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist;
serotonergic antagonist;
vasodilator agent
pioglitazone[no description available]medium40aromatic ether;
pyridines;
thiazolidinediones		antidepressant;
cardioprotective agent;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hypoglycemic agent;
insulin-sensitizing drug;
PPARgamma agonist;
xenobiotic
praziquantel[no description available]medium20isoquinolines
primidone[no description available]medium20pyrimidoneanticonvulsant;
environmental contaminant;
xenobiotic
probenecid[no description available]medium180benzoic acids;
sulfonamide		uricosuric drug
probucol[no description available]medium20dithioketal;
polyphenol		anti-inflammatory drug;
anticholesteremic drug;
antilipemic drug;
antioxidant;
cardiovascular drug
propofol[no description available]medium20phenolsanticonvulsant;
antiemetic;
intravenous anaesthetic;
radical scavenger;
sedative
propranolol[no description available]medium30naphthalenes;
propanolamine;
secondary amine		anti-arrhythmia drug;
antihypertensive agent;
anxiolytic drug;
beta-adrenergic antagonist;
environmental contaminant;
human blood serum metabolite;
vasodilator agent;
xenobiotic
pyrimethamine[no description available]medium20aminopyrimidine;
monochlorobenzenes		antimalarial;
antiprotozoal drug;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor
raloxifene[no description available]medium201-benzothiophenes;
aromatic ketone;
N-oxyethylpiperidine;
phenols		bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
ranitidine[no description available]medium20aralkylamine
riluzole[no description available]medium30benzothiazoles
risperidone[no description available]medium201,2-benzoxazoles;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
psychotropic drug;
second generation antipsychotic;
serotonergic antagonist
sulfabenzamide[no description available]medium20benzenes;
sulfonamide antibiotic;
sulfonamide		antibacterial drug;
antimicrobial drug
sulfamethizole[no description available]medium20sulfonamide antibiotic;
sulfonamide;
thiadiazoles		antiinfective agent;
antimicrobial agent;
drug allergen;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor
sulfanilamide[no description available]medium20substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial agent;
drug allergen;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
sulfasalazine[no description available]medium20
sulfinpyrazone[no description available]medium20pyrazolidines;
sulfoxide		uricosuric drug
sumatriptan[no description available]medium20sulfonamide;
tryptamines		serotonergic agonist;
vasoconstrictor agent
gatifloxacin[no description available]medium20N-arylpiperazine;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone		antiinfective agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
terfenadine[no description available]medium20diarylmethane
ticlopidine[no description available]medium20monochlorobenzenes;
thienopyridine		anticoagulant;
fibrin modulating drug;
hematologic agent;
P2Y12 receptor antagonist;
platelet aggregation inhibitor
tolazamide[no description available]medium20N-sulfonylureahypoglycemic agent;
potassium channel blocker
tolbutamide[no description available]medium60N-sulfonylureahuman metabolite;
hypoglycemic agent;
insulin secretagogue;
potassium channel blocker
tolmetin[no description available]medium20aromatic ketone;
monocarboxylic acid;
pyrroles		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
trifluoperazine[no description available]medium30N-alkylpiperazine;
N-methylpiperazine;
organofluorine compound;
phenothiazines		antiemetic;
calmodulin antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor;
phenothiazine antipsychotic drug
trimethadione[no description available]medium20oxazolidinoneanticonvulsant;
geroprotector
trimethoprim[no description available]medium20aminopyrimidine;
methoxybenzenes		antibacterial drug;
diuretic;
drug allergen;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
environmental contaminant;
xenobiotic
troglitazone[no description available]medium20chromanes;
thiazolidinone		anticoagulant;
anticonvulsant;
antineoplastic agent;
antioxidant;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
hypoglycemic agent;
platelet aggregation inhibitor;
vasodilator agent
pirinixic acid[no description available]medium10aryl sulfide;
organochlorine compound;
pyrimidines
ici 204,219[no description available]medium20carbamate ester;
indoles;
N-sulfonylcarboxamide		anti-asthmatic agent;
leukotriene antagonist
zolpidem[no description available]medium20imidazopyridinecentral nervous system depressant;
GABA agonist;
sedative
zomepirac[no description available]medium20aromatic ketone;
monocarboxylic acid;
monochlorobenzenes;
pyrroles		cardiovascular drug;
non-steroidal anti-inflammatory drug
oxyphenonium[no description available]medium20acylcholine
cephaloridine[no description available]medium20beta-lactam antibiotic allergen;
cephalosporin;
semisynthetic derivative		antibacterial drug
sorbitol[no description available]medium20glucitolcathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent
floxuridine[no description available]medium20nucleoside analogue;
organofluorine compound;
pyrimidine 2'-deoxyribonucleoside		antimetabolite;
antineoplastic agent;
antiviral drug;
radiosensitizing agent
isoproterenol hydrochloride[no description available]medium20catechols
spironolactone[no description available]medium2003-oxo-Delta(4) steroid;
oxaspiro compound;
steroid lactone;
thioester		aldosterone antagonist;
antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
spironolactone[no description available]medium2013-oxo-Delta(4) steroid;
oxaspiro compound;
steroid lactone;
thioester		aldosterone antagonist;
antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic
prednisone[no description available]medium3011-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
immunosuppressive agent;
prodrug
prednisone[no description available]medium3111-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
immunosuppressive agent;
prodrug
estrone[no description available]medium6017-oxo steroid;
3-hydroxy steroid;
phenolic steroid;
phenols		antineoplastic agent;
bone density conservation agent;
estrogen;
human metabolite;
mouse metabolite
promazine hydrochloride[no description available]medium20hydrochloride
2-acetylaminofluorene[no description available]medium102-acetamidofluorenesantimitotic;
carcinogenic agent;
epitope;
mutagen
idoxuridine[no description available]medium20organoiodine compound;
pyrimidine 2'-deoxyribonucleoside		antiviral drug;
DNA synthesis inhibitor
pilocarpine[no description available]medium30pilocarpineantiglaucoma drug
triiodothyronine[no description available]medium302-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine		human metabolite;
mouse metabolite;
thyroid hormone
isonicotinic acid[no description available]medium10pyridinemonocarboxylic acidalgal metabolite;
human metabolite
carbon tetrachloride[no description available]medium20chlorocarbon;
chloromethanes		hepatotoxic agent;
refrigerant
physostigmine[no description available]medium20carbamate ester;
indole alkaloid		antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic
ethinyl estradiol[no description available]medium2017-hydroxy steroid;
3-hydroxy steroid;
terminal acetylenic compound		xenoestrogen
promethazine hydrochloride[no description available]medium20hydrochlorideanti-allergic agent;
anticoronaviral agent;
antiemetic;
antipruritic drug;
geroprotector;
H1-receptor antagonist;
local anaesthetic;
sedative
levodopa[no description available]medium50amino acid zwitterion;
dopa;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		allelochemical;
antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
hapten;
human metabolite;
mouse metabolite;
neurotoxin;
plant growth retardant;
plant metabolite;
prodrug
acetylcholine chloride[no description available]medium20quaternary ammonium salt
methoxamine hydrochloride[no description available]medium20dimethoxybenzene
dimethylnitrosamine[no description available]medium20nitrosaminegeroprotector;
mutagen
lactose[no description available]medium20lactose
primaquine phosphate[no description available]medium20
colchicine[no description available]medium20alkaloid;
colchicine		anti-inflammatory agent;
gout suppressant;
mutagen
gallamine triethiodide[no description available]medium20
uracil mustard[no description available]medium20aminouracil;
nitrogen mustard
chloroform[no description available]medium20chloromethanes;
one-carbon compound		carcinogenic agent;
central nervous system drug;
inhalation anaesthetic;
non-polar solvent;
refrigerant
dimethylformamide[no description available]medium10formamides;
volatile organic compound		geroprotector;
hepatotoxic agent;
polar aprotic solvent
norethindrone[no description available]medium2017beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
terminal acetylenic compound;
tertiary alcohol		progestin;
synthetic oral contraceptive
medroxyprogesterone acetate[no description available]medium2020-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
corticosteroid;
steroid ester		adjuvant;
androgen;
antineoplastic agent;
antioxidant;
female contraceptive drug;
inhibitor;
progestin;
synthetic oral contraceptive
mestranol[no description available]medium2017beta-hydroxy steroid;
aromatic ether;
terminal acetylenic compound		prodrug;
xenoestrogen
arginine[no description available]medium30arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
tromethamine[no description available]medium20primary amino compound;
triol		buffer
trichloroethylene[no description available]medium20chloroethenesinhalation anaesthetic;
mouse metabolite
cyclizine[no description available]medium20N-alkylpiperazineantiemetic;
central nervous system depressant;
cholinergic antagonist;
H1-receptor antagonist;
local anaesthetic
rotenone[no description available]medium40organic heteropentacyclic compound;
rotenones		antineoplastic agent;
metabolite;
mitochondrial NADH:ubiquinone reductase inhibitor;
phytogenic insecticide;
piscicide;
toxin
isosorbide dinitrate[no description available]medium20glucitol derivative;
nitrate ester		nitric oxide donor;
vasodilator agent
hexachlorobutadiene[no description available]medium10organochlorine compound
phenothiazine[no description available]medium20phenothiazineferroptosis inhibitor;
plant metabolite;
radical scavenger
2-bromophenol[no description available]medium20bromophenolmarine metabolite
3-dinitrobenzene[no description available]medium10dinitrobenzeneneurotoxin
pyridostigmine bromide[no description available]medium30pyridinium salt
4,4'-diaminodiphenylmethane[no description available]medium20aromatic amineallergen;
carcinogenic agent
phenylisothiocyanate[no description available]medium20isothiocyanateallergen;
reagent
4-bromophenol[no description available]medium20bromophenolhuman urinary metabolite;
human xenobiotic metabolite;
marine metabolite;
mouse metabolite;
persistent organic pollutant;
rat metabolite
2-bromoethylamine[no description available]medium20
allyl alcohol[no description available]medium20primary allylic alcohol;
propenol		antibacterial agent;
fungicide;
herbicide;
insecticide;
plant metabolite
bromobenzene[no description available]medium20bromoarene;
bromobenzenes;
volatile organic compound		hepatotoxic agent;
mouse metabolite;
non-polar solvent
imipramine hydrochloride[no description available]medium20hydrochlorideantidepressant
mephobarbital[no description available]medium20barbituratesanticonvulsant
edrophonium chloride[no description available]medium20chloride salt;
quaternary ammonium salt		antidote;
diagnostic agent;
EC 3.1.1.8 (cholinesterase) inhibitor
di-n-pentyl phthalate[no description available]medium20diester;
phthalate ester		plasticiser
cinchophen[no description available]medium20quinolines
phenazopyridine hydrochloride[no description available]medium20hydrochloridecarcinogenic agent;
local anaesthetic;
non-narcotic analgesic
tetrracaine hydrochloride[no description available]medium20benzoate ester
diphenhydramine hydrochloride[no description available]medium20hydrochloride;
organoammonium salt		anti-allergic agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
sedative
tripelennamine hydrochloride[no description available]medium20
ethynodiol diacetate[no description available]medium20steroid ester;
terminal acetylenic compound		contraceptive drug;
estrogen receptor modulator;
synthetic oral contraceptive
hydrazine[no description available]medium20azane;
hydrazines		EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
monocrotaline[no description available]medium30pyrrolizidine alkaloid
azacitidine[no description available]medium20N-glycosyl-1,3,5-triazine;
nucleoside analogue		antineoplastic agent
pseudoephedrine hydrochloride[no description available]medium20hydrochlorideplant metabolite
procarbazine hydrochloride[no description available]medium20hydrochlorideantineoplastic agent
betamethasone[no description available]medium2011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		anti-asthmatic agent;
anti-inflammatory drug;
immunosuppressive agent
cyproterone acetate[no description available]medium2020-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
chlorinated steroid;
steroid ester		androgen antagonist;
geroprotector;
progestin
lithocholic acid[no description available]medium20bile acid;
C24-steroid;
monohydroxy-5beta-cholanic acid		geroprotector;
human metabolite;
mouse metabolite
chenodeoxycholic acid[no description available]medium40bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
amitriptyline hydrochloride[no description available]medium20organic tricyclic compound
1-naphthylisothiocyanate[no description available]medium20isothiocyanateinsecticide
isoxsuprine hydrochloride[no description available]medium20alkylbenzene
betaine hydrochloride[no description available]medium20
acetylcysteine[no description available]medium30acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary
3-hydroxyacetanilide[no description available]medium20acetamides;
phenols		non-narcotic analgesic
methoxyacetic acid[no description available]medium20ether;
monocarboxylic acid		antineoplastic agent;
apoptosis inducer;
human xenobiotic metabolite;
mutagen
erythromycin[no description available]medium20cyclic ketone;
erythromycin
cyproheptadine hydrochloride (anhydrous)[no description available]medium20hydrochloride
vancomycin[no description available]medium20glycopeptideantibacterial drug;
antimicrobial agent;
bacterial metabolite
pregnenolone carbonitrile[no description available]medium10aliphatic nitrile
ibufenac[no description available]medium20monocarboxylic acidEC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
hepatotoxic agent;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
2,3,7,8-tetrachlorodibenzodioxine[no description available]medium10polychlorinated dibenzodioxine
paraquat[no description available]medium20organic cationgeroprotector;
herbicide
pimozide[no description available]medium20benzimidazoles;
heteroarylpiperidine;
organofluorine compound		antidyskinesia agent;
dopaminergic antagonist;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist
stavudine[no description available]medium20dihydrofuran;
nucleoside analogue;
organic molecular entity		antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
streptomycin[no description available]medium20antibiotic antifungal drug;
antibiotic fungicide;
streptomycins		antibacterial drug;
antifungal agrochemical;
antimicrobial agent;
antimicrobial drug;
bacterial metabolite;
protein synthesis inhibitor
clonidine hydrochloride[no description available]medium20dichlorobenzene
cladribine[no description available]medium20organochlorine compound;
purine 2'-deoxyribonucleoside		antineoplastic agent;
immunosuppressive agent
ethylene dimethanesulfonate[no description available]medium20
mexiletine hydrochloride[no description available]medium20hydrochlorideanti-arrhythmia drug
beclomethasone dipropionate[no description available]medium2011beta-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
corticosteroid;
enone;
glucocorticoid;
propanoate ester;
steroid ester		anti-arrhythmia drug;
anti-asthmatic drug;
anti-inflammatory drug;
prodrug
vidarabine[no description available]medium20beta-D-arabinoside;
purine nucleoside		antineoplastic agent;
bacterial metabolite;
nucleoside antibiotic
metoclopramide hydrochloride[no description available]medium20
zalcitabine[no description available]medium20pyrimidine 2',3'-dideoxyribonucleosideantimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor
carbendazim[no description available]medium20benzimidazole fungicide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester		antifungal agrochemical;
antinematodal drug;
metabolite;
microtubule-destabilising agent
ethionine[no description available]medium20S-ethylhomocysteineantimetabolite;
carcinogenic agent
danazol[no description available]medium2017beta-hydroxy steroid;
terminal acetylenic compound		anti-estrogen;
estrogen antagonist;
geroprotector
disopyramide phosphate[no description available]medium20organoammonium phosphate
ursodeoxycholic acid[no description available]medium20bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid		human metabolite;
mouse metabolite
butylated hydroxytoluene[no description available]medium20phenolsantioxidant;
ferroptosis inhibitor;
food additive;
geroprotector
amoxicillin[no description available]medium20penicillin allergen;
penicillin		antibacterial drug
moricizine hydrochloride[no description available]medium20hydrochlorideanti-arrhythmia drug
zidovudine[no description available]medium20azide;
pyrimidine 2',3'-dideoxyribonucleoside		antimetabolite;
antiviral drug;
HIV-1 reverse transcriptase inhibitor
pirprofen[no description available]medium20pyrroline
serentil[no description available]medium20organosulfonate saltdopaminergic antagonist;
first generation antipsychotic
tobramycin[no description available]medium20amino cyclitol glycosideantibacterial agent;
antimicrobial agent;
toxin
paclitaxel[no description available]medium40taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
etoposide[no description available]medium20beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor
propafenone hydrochloride[no description available]medium20hydrochlorideanti-arrhythmia drug
ribavirin[no description available]medium201-ribosyltriazole;
aromatic amide;
monocarboxylic acid amide;
primary carboxamide		anticoronaviral agent;
antiinfective agent;
antimetabolite;
antiviral agent;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
carbidopa[no description available]medium20catechols;
hydrate;
hydrazines;
monocarboxylic acid		antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor
cephradine[no description available]medium20beta-lactam antibiotic allergen;
cephalosporin		antibacterial drug
ticrynafen[no description available]medium20aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid;
thiophenes		antihypertensive agent;
hepatotoxic agent;
loop diuretic
methyldopa[no description available]medium20L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid		alpha-adrenergic agonist;
antihypertensive agent;
hapten;
peripheral nervous system drug;
sympatholytic agent
bezafibrate[no description available]medium20aromatic ether;
monocarboxylic acid amide;
monocarboxylic acid;
monochlorobenzenes		antilipemic drug;
environmental contaminant;
geroprotector;
xenobiotic
sq-11725[no description available]medium20
nonachlazine[no description available]medium10
benoxaprofen[no description available]medium201,3-benzoxazoles;
monocarboxylic acid;
monochlorobenzenes		antipsoriatic;
antipyretic;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
hepatotoxic agent;
nephrotoxin;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
protein kinase C agonist
permethrin[no description available]medium20cyclopropanecarboxylate ester;
cyclopropanes		agrochemical;
ectoparasiticide;
pyrethroid ester acaricide;
pyrethroid ester insecticide;
scabicide
flecainide acetate[no description available]medium20acetate saltanti-arrhythmia drug
nicardipine hydrochloride[no description available]medium20dihydropyridinegeroprotector
epirubicin[no description available]medium20aminoglycoside;
anthracycline antibiotic;
anthracycline;
deoxy hexoside;
monosaccharide derivative;
p-quinones;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		antimicrobial agent;
antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
indacrinone[no description available]medium20
paroxetine[no description available]medium20aromatic ether;
benzodioxoles;
organofluorine compound;
piperidines		antidepressant;
anxiolytic drug;
hepatotoxic agent;
P450 inhibitor;
serotonin uptake inhibitor
captopril[no description available]medium20alkanethiol;
L-proline derivative;
N-acylpyrrolidine;
pyrrolidinemonocarboxylic acid		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
butoconazole nitrate[no description available]medium20aryl sulfide;
conazole antifungal drug;
imidazole antifungal drug;
imidazoles;
organic nitrate salt
cefadroxil anhydrous[no description available]medium20cephalosporinantibacterial drug
fialuridine[no description available]medium20
mitoxantrone hydrochloride[no description available]medium20hydrochlorideantineoplastic agent
cefotetan[no description available]medium20
bambuterol[no description available]medium20carbamate ester;
phenylethanolamines		anti-asthmatic drug;
beta-adrenergic agonist;
bronchodilator agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
prodrug;
sympathomimetic agent;
tocolytic agent
atomoxetine[no description available]medium20aromatic ether;
secondary amino compound;
toluenes		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
xenobiotic
quinapril[no description available]medium20dicarboxylic acid monoester;
ethyl ester;
isoquinolines;
tertiary carboxamide		antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug
alpidem[no description available]medium20imidazoles
temafloxacin[no description available]medium20amino acid;
monocarboxylic acid;
N-arylpiperazine;
organofluorine compound;
quinolone antibiotic;
quinolone;
secondary amino compound;
tertiary amino compound
clinafloxacin[no description available]medium20quinolines
zileuton[no description available]medium201-benzothiophenes;
ureas		anti-asthmatic drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
ferroptosis inhibitor;
leukotriene antagonist;
non-steroidal anti-inflammatory drug
mibefradil[no description available]medium20tetralinsT-type calcium channel blocker
bromfenac[no description available]medium20aromatic amino acid;
benzophenones;
organobromine compound;
substituted aniline		non-narcotic analgesic;
non-steroidal anti-inflammatory drug
lamivudine[no description available]medium20monothioacetal;
nucleoside analogue;
oxacycle;
primary alcohol		allergen;
anti-HBV agent;
antiviral drug;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor;
HIV-1 reverse transcriptase inhibitor;
prodrug
valsartan[no description available]medium20biphenylyltetrazole;
monocarboxylic acid amide;
monocarboxylic acid		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
tasosartan[no description available]medium20biphenyls
saquinavir monomethanesulfonate[no description available]medium20organic molecular entity
adenosine[no description available]medium60adenosines;
purines D-ribonucleoside		analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent
allyl formate[no description available]medium20
desferrioxamine b mesylate[no description available]medium20methanesulfonate saltantidote;
ferroptosis inhibitor;
iron chelator
bupropion hydrochloride[no description available]medium20aromatic ketone
trazodone hydrochloride[no description available]medium20hydrochlorideadrenergic antagonist;
antidepressant;
H1-receptor antagonist;
sedative;
serotonin uptake inhibitor
trovafloxacin[no description available]medium30
verapamil hydrochloride[no description available]medium20
ciprofloxacin hydrochloride anhydrous[no description available]medium20hydrochlorideantibacterial drug;
antiinfective agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor
amantadine hydrochloride[no description available]medium20hydrochlorideantiviral agent;
dopamine agonist;
NMDA receptor antagonist
dobutamine hydrochloride[no description available]medium20hydrochloridebeta-adrenergic agonist;
cardiotonic drug;
sympathomimetic agent
iopamidol[no description available]medium20benzenedicarboxamide;
organoiodine compound;
pentol		environmental contaminant;
radioopaque medium;
xenobiotic
sulconazole, mononitrate, (+-)-isomer[no description available]medium20conazole antifungal drug;
imidazole antifungal drug;
organic nitrate salt
telmisartan[no description available]medium20benzimidazoles;
biphenyls;
carboxybiphenyl		angiotensin receptor antagonist;
antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
environmental contaminant;
xenobiotic
trimethobenzamide monohydrochloride[no description available]medium20
amiloride hydrochloride[no description available]medium20hydratediuretic;
sodium channel blocker
econazole nitrate[no description available]medium20
sertraline[no description available]medium20dichlorobenzene;
secondary amino compound;
tetralins		antidepressant;
serotonin uptake inhibitor
lomefloxacin hydrochloride[no description available]medium20hydrochlorideantimicrobial agent;
antitubercular agent;
photosensitizing agent
flunoxaprofen[no description available]medium201,3-benzoxazoles;
monocarboxylic acid;
organofluorine compound		antirheumatic drug;
hepatotoxic agent;
non-steroidal anti-inflammatory drug;
protein kinase C agonist
tianeptine[no description available]medium20dibenzothiazepine;
monocarboxylic acid;
organochlorine compound
loperamide hydrochloride[no description available]medium20hydrochlorideanticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist
grepafloxacin[no description available]medium20fluoroquinolone antibiotic;
quinolines;
quinolone antibiotic
2-naphthylisothiocyanate[no description available]medium20
rosiglitazone[no description available]medium20aminopyridine;
thiazolidinediones		EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
insulin-sensitizing drug
chloroquine diphosphate[no description available]medium20
orphenadrine citrate[no description available]medium20citrate saltH1-receptor antagonist;
muscarinic antagonist;
muscle relaxant;
NMDA receptor antagonist;
parasympatholytic
ketorolac tromethamine[no description available]medium20organoammonium saltanalgesic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor
clarithromycin[no description available]medium20macrolide antibioticantibacterial drug;
environmental contaminant;
protein synthesis inhibitor;
xenobiotic
n-(3,5-dichlorophenyl)succinimide[no description available]medium20pyrrolidines
phentolamine mesylate[no description available]medium20
oxybutynin hydrochloride[no description available]medium20hydrochloride
1-cyano-2-hydroxy-3-butene[no description available]medium10secondary alcohol
cordium[no description available]medium20hydrate;
hydrochloride
bosentan anhydrous[no description available]medium20primary alcohol;
pyrimidines;
sulfonamide		antihypertensive agent;
endothelin receptor antagonist
methotrexate[no description available]medium20dicarboxylic acid;
monocarboxylic acid amide;
pteridines		abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent
dilevalol[no description available]medium102-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide
nsc-141549[no description available]medium20
levofloxacin[no description available]medium209-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid;
fluoroquinolone antibiotic;
quinolone antibiotic		antibacterial drug;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor
naproxen[no description available]medium20methoxynaphthalene;
monocarboxylic acid		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
gout suppressant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic
biotin[no description available]medium40biotins;
vitamin B7		coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite
aflatoxin b1[no description available]medium20aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human metabolite
troleandomycin[no description available]medium20acetate ester;
epoxide;
macrolide antibiotic;
monosaccharide derivative;
polyketide;
semisynthetic derivative		EC 1.14.13.97 (taurochenodeoxycholate 6alpha-hydroxylase) inhibitor;
xenobiotic
fludrocortisone acetate[no description available]medium2011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
fluorinated steroid;
mineralocorticoid;
tertiary alpha-hydroxy ketone
vincristine sulfate[no description available]medium20organic sulfate saltantineoplastic agent;
geroprotector
acivicin[no description available]medium20isoxazoles;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		antileishmanial agent;
antimetabolite;
antimicrobial agent;
antineoplastic agent;
EC 2.3.2.2 (gamma-glutamyltransferase) inhibitor;
glutamine antagonist;
metabolite
ritonavir[no description available]medium201,3-thiazoles;
carbamate ester;
carboxamide;
L-valine derivative;
ureas		antiviral drug;
environmental contaminant;
HIV protease inhibitor;
xenobiotic
glucosamine[no description available]medium30D-glucosamineEscherichia coli metabolite;
geroprotector;
mouse metabolite
puromycin[no description available]medium20puromycinsantiinfective agent;
antimicrobial agent;
antineoplastic agent;
EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor;
EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor;
nucleoside antibiotic;
protein synthesis inhibitor
(+)-limonene[no description available]medium20limoneneplant metabolite
quinidine[no description available]medium80cinchona alkaloidalpha-adrenergic antagonist;
anti-arrhythmia drug;
antimalarial;
drug allergen;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
muscarinic antagonist;
P450 inhibitor;
potassium channel blocker;
sodium channel blocker
griseofulvin[no description available]medium201-benzofurans;
antibiotic antifungal drug;
benzofuran antifungal drug;
organochlorine compound;
oxaspiro compound		antibacterial agent;
Penicillium metabolite
cefoxitin[no description available]medium20beta-lactam antibiotic allergen;
cephalosporin;
cephamycin;
semisynthetic derivative		antibacterial drug
moxalactam disodium[no description available]medium20
abacavir[no description available]medium202,6-diaminopurinesantiviral drug;
drug allergen;
HIV-1 reverse transcriptase inhibitor
mometasone furoate[no description available]medium2011beta-hydroxy steroid;
2-furoate ester;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
organochlorine compound;
steroid ester		anti-allergic agent;
anti-inflammatory drug
nortriptyline hydrochloride[no description available]medium20organic tricyclic compoundgeroprotector
erythromycin estolate[no description available]medium20aminoglycoside sulfate salt;
erythromycin derivative		enzyme inhibitor
kanamycin sulfate[no description available]medium20aminoglycoside sulfate saltantibacterial drug;
geroprotector
paromomycin sulfate[no description available]medium20
chloramphenicol palmitate[no description available]medium20hexadecanoate ester
calcium pantothenate[no description available]medium20polymer
doxorubicin hydrochloride[no description available]medium20anthracycline
maleic acid[no description available]medium20butenedioic acidalgal metabolite;
mouse metabolite;
plant metabolite
tretinoin[no description available]medium70retinoic acid;
vitamin A		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule
cyanoginosin lr[no description available]medium20microcystinbacterial metabolite;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
environmental contaminant;
xenobiotic
cerivastatin[no description available]medium20dihydroxy monocarboxylic acid;
pyridines;
statin (synthetic)
zithromax[no description available]medium20macrolide antibioticantibacterial drug;
environmental contaminant;
xenobiotic
drf 2725[no description available]medium20
dactinomycin[no description available]medium20actinomycinmutagen
azaserine[no description available]medium20carboxylic ester;
diazo compound;
L-serine derivative;
non-proteinogenic L-alpha-amino acid		antifungal agent;
antimetabolite;
antimicrobial agent;
antineoplastic agent;
glutamine antagonist;
immunosuppressive agent;
metabolite
sodium bicarbonate[no description available]medium30one-carbon compound;
organic sodium salt		antacid;
food anticaking agent
arsenic trioxide[no description available]medium20arsenic oxideantineoplastic agent;
insecticide
idarubicin hydrochloride[no description available]medium20anthracycline
mercaptopurine[no description available]medium20aryl thiol;
purines;
thiocarbonyl compound		anticoronaviral agent;
antimetabolite;
antineoplastic agent
thiothixene[no description available]medium20N-methylpiperazineanticoronaviral agent
methimazole[no description available]medium201,3-dihydroimidazole-2-thionesantithyroid drug
sulindac[no description available]medium20monocarboxylic acid;
organofluorine compound;
sulfoxide		analgesic;
antineoplastic agent;
antipyretic;
apoptosis inducer;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug;
tocolytic agent
capsaicin[no description available]medium40capsaicinoidnon-narcotic analgesic;
TRPV1 agonist;
voltage-gated sodium channel blocker
thioguanine anhydrous[no description available]medium202-aminopurinesanticoronaviral agent;
antimetabolite;
antineoplastic agent
(1R,2S)-tranylcypromine hydrochloride[no description available]medium20hydrochloride
thioacetamide[no description available]medium30thiocarboxamidehepatotoxic agent
digoxin[no description available]medium20cardenolide glycoside;
steroid saponin		anti-arrhythmia drug;
cardiotonic drug;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
epitope
streptozocin[no description available]medium20
tamoxifen[no description available]medium40stilbenoid;
tertiary amino compound		angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator
hmr 3647[no description available]medium20
quinine[no description available]medium200cinchona alkaloidantimalarial;
muscle relaxant;
non-narcotic analgesic
tolcapone[no description available]medium202-nitrophenols;
benzophenones;
catechols		antiparkinson drug;
EC 2.1.1.6 (catechol O-methyltransferase) inhibitor
retinol palmitate[no description available]medium20all-trans-retinyl ester;
retinyl palmitate		antioxidant;
Escherichia coli metabolite;
human xenobiotic metabolite
vitamin d 2[no description available]medium20hydroxy seco-steroid;
seco-ergostane;
vitamin D		bone density conservation agent;
nutraceutical;
plant metabolite;
rodenticide
amphotericin b[no description available]medium20antibiotic antifungal drug;
macrolide antibiotic;
polyene antibiotic		antiamoebic agent;
antiprotozoal drug;
bacterial metabolite
eprosartan[no description available]medium20dicarboxylic acid;
imidazoles;
thiophenes		angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic
montelukast[no description available]medium20aliphatic sulfide;
monocarboxylic acid;
quinolines		anti-arrhythmia drug;
anti-asthmatic drug;
leukotriene antagonist
timolol maleate[no description available]medium20maleate saltanti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist
brompheniramine maleate[no description available]medium20maleate saltanti-allergic agent
chlorpheniramine maleate[no description available]medium20organic molecular entity
clemastine fumarate[no description available]medium20fumarate saltanti-allergic agent;
antipruritic drug;
H1-receptor antagonist;
muscarinic antagonist
methylergonovine maleate[no description available]medium20ergoline alkaloidgeroprotector
entacapone[no description available]medium202-nitrophenols;
catechols;
monocarboxylic acid amide;
nitrile		antidyskinesia agent;
antiparkinson drug;
central nervous system drug;
EC 2.1.1.6 (catechol O-methyltransferase) inhibitor
estradiol-17 beta-glucuronide[no description available]medium203-hydroxy steroid;
steroid glucosiduronic acid
isotretinoin[no description available]medium20retinoic acidantineoplastic agent;
keratolytic drug;
teratogenic agent
cis-flupenthixol dihydrochloride[no description available]medium10hydrochloridegeroprotector
cyclosporine[no description available]medium20homodetic cyclic peptideanti-asthmatic drug;
anticoronaviral agent;
antifungal agent;
antirheumatic drug;
carcinogenic agent;
dermatologic drug;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
geroprotector;
immunosuppressive agent;
metabolite
phenoxybenzamine hydrochloride[no description available]medium20organic molecular entity
acitretin[no description available]medium20acitretin;
alpha,beta-unsaturated monocarboxylic acid;
retinoid		keratolytic drug
ly 163892[no description available]medium20carbacephem;
zwitterion		antibacterial drug;
antimicrobial agent
nalmefene[no description available]medium20morphinane alkaloid
furazolidone[no description available]medium20
fluvoxamine[no description available]medium20(trifluoromethyl)benzenes;
5-methoxyvalerophenone O-(2-aminoethyl)oxime		antidepressant;
anxiolytic drug;
serotonin uptake inhibitor
octylmethoxycinnamate[no description available]medium20cinnamate ester
naltrexone[no description available]medium20cyclopropanes;
morphinane-like compound;
organic heteropentacyclic compound		antidote to opioid poisoning;
central nervous system depressant;
environmental contaminant;
mu-opioid receptor antagonist;
xenobiotic
lisinopril[no description available]medium20dipeptideEC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
benazepril[no description available]medium20benzazepine;
dicarboxylic acid monoester;
ethyl ester;
lactam		EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug
vinblastine sulfate[no description available]medium20
trientine hydrochloride[no description available]medium20
dextromethorphan hydrobromide[no description available]medium20hydrate;
hydrobromide
ceftazidime[no description available]medium20cephalosporin;
oxime O-ether		antibacterial drug;
drug allergen;
EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor
famotidine[no description available]medium201,3-thiazoles;
guanidines;
sulfonamide		anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor
fenoterol[no description available]medium20hydrobromidebeta-adrenergic agonist;
bronchodilator agent;
sympathomimetic agent
aztreonam[no description available]medium20beta-lactam antibiotic allergen;
monobactam		antibacterial drug;
drug allergen;
EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor
enclomiphene citrate[no description available]medium10
diphenoxylate hydrochloride[no description available]medium20hydrochlorideantidiarrhoeal drug
ergonovine maleate[no description available]medium20maleate saltdiagnostic agent;
oxytocic
dantrolene sodium[no description available]medium20
nitrofurantoin[no description available]medium20imidazolidine-2,4-dione;
nitrofuran antibiotic;
organonitrogen heterocyclic antibiotic;
organooxygen heterocyclic antibiotic		antibacterial drug;
antiinfective agent;
hepatotoxic agent
ursodoxicoltaurine[no description available]medium10bile acid taurine conjugateanti-inflammatory agent;
apoptosis inhibitor;
bone density conservation agent;
cardioprotective agent;
human metabolite;
neuroprotective agent
molindone hydrochloride[no description available]medium20indoles
gentamicin sulfate[no description available]medium10
baci-im[no description available]medium20homodetic cyclic peptide;
polypeptide;
zwitterion		antibacterial agent;
antimicrobial agent
cytidine diphosphate choline[no description available]medium20nucleotide-(amino alcohol)s;
phosphocholines		human metabolite;
mouse metabolite;
neuroprotective agent;
psychotropic drug;
Saccharomyces cerevisiae metabolite
clindamycin hydrochloride[no description available]medium20S-glycosyl compound
quinine sulfate[no description available]medium20hydrate
cefotiam hydrochloride[no description available]medium20
potassium aminobenzoate[no description available]medium20
methicillin sodium[no description available]medium20organic sodium salt
nafcillin sodium[no description available]medium20organic sodium salt
penicillin g sodium[no description available]medium20organic sodium salt
cefamandole nafate[no description available]medium20organic sodium saltantibacterial drug
cephapirin sodium[no description available]medium20cephalosporin;
organic sodium salt		antibacterial drug
sodium cephalothin[no description available]medium20organic sodium salt
dicloxacillin sodium[no description available]medium20hydrate
azlocillin sodium[no description available]medium20organic sodium salt
ascorbic acid[no description available]medium50ascorbic acid;
vitamin C		coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent
novobiocin[no description available]medium20carbamate ester;
ether;
hexoside;
hydroxycoumarin;
monocarboxylic acid amide;
monosaccharide derivative;
phenols		antibacterial agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
Escherichia coli metabolite;
hepatoprotective agent
tetracycline[no description available]medium20
piroxicam[no description available]medium20benzothiazine;
monocarboxylic acid amide;
pyridines		analgesic;
antirheumatic drug;
cyclooxygenase 1 inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
acenocoumarol[no description available]medium20C-nitro compound;
hydroxycoumarin;
methyl ketone		anticoagulant;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
isoxicam[no description available]medium20benzothiazine;
isoxazoles;
monocarboxylic acid amide		antirheumatic drug;
non-steroidal anti-inflammatory drug
warfarin[no description available]medium40benzenes;
hydroxycoumarin;
methyl ketone
chlortetracycline hydrochloride[no description available]medium20
methacycline monohydrochloride[no description available]medium20
minocycline hydrochloride[no description available]medium20
demeclocycline hydrochloride[no description available]medium20
folic acid[no description available]medium20folic acids;
N-acyl-amino acid		human metabolite;
mouse metabolite;
nutrient
rifampin[no description available]medium20cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor
clozapine[no description available]medium20benzodiazepine;
N-arylpiperazine;
N-methylpiperazine;
organochlorine compound		adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
GABA antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
xenobiotic
dacarbazine[no description available]medium20dacarbazine
didanosine[no description available]medium20purine 2',3'-dideoxyribonucleosideantimetabolite;
antiviral drug;
EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor;
geroprotector;
HIV-1 reverse transcriptase inhibitor
allopurinol[no description available]medium20nucleobase analogue;
organic heterobicyclic compound		antimetabolite;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
gout suppressant;
radical scavenger
citrovorum factor[no description available]medium20tetrahydrofolic acid
rifabutin[no description available]medium20
4-aminophenol[no description available]medium10aminophenolallergen;
metabolite
aspirin[no description available]medium110benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent
celecoxib[no description available]medium10organofluorine compound;
pyrazoles;
sulfonamide;
toluenes		cyclooxygenase 2 inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug
clomiphene[no description available]medium10tertiary amineestrogen antagonist;
estrogen receptor modulator
disulfiram[no description available]medium20organic disulfide;
organosulfur acaricide		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
EC 3.1.1.1 (carboxylesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
ferroptosis inducer;
fungicide;
NF-kappaB inhibitor
sulfobromophthalein[no description available]medium102-benzofurans;
organobromine compound;
organosulfonic acid;
phenols		dye
telenzepine[no description available]medium10benzodiazepine
temozolomide[no description available]medium10imidazotetrazine;
monocarboxylic acid amide;
triazene derivative		alkylating agent;
antineoplastic agent;
prodrug
diquat[no description available]medium10organic cationdefoliant;
herbicide
n-pentanoic acid[no description available]medium10short-chain fatty acid;
straight-chain saturated fatty acid		plant metabolite
lovastatin[no description available]medium10delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		anticholesteremic drug;
antineoplastic agent;
Aspergillus metabolite;
prodrug
tolrestat[no description available]medium10naphthalenesEC 1.1.1.21 (aldehyde reductase) inhibitor
simvastatin[no description available]medium10delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
statin (semi-synthetic)		EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
ferroptosis inducer;
geroprotector;
prodrug
diltiazem hydrochloride[no description available]medium10hydrochlorideantihypertensive agent;
calcium channel blocker;
vasodilator agent
gefitinib[no description available]medium10aromatic ether;
monochlorobenzenes;
monofluorobenzenes;
morpholines;
quinazolines;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
epidermal growth factor receptor antagonist
cox 189[no description available]medium10amino acid;
monocarboxylic acid;
organochlorine compound;
organofluorine compound;
secondary amino compound		cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
olmesartan[no description available]medium10biphenylyltetrazoleangiotensin receptor antagonist;
antihypertensive agent
lapatinib[no description available]medium10furans;
organochlorine compound;
organofluorine compound;
quinazolines		antineoplastic agent;
tyrosine kinase inhibitor
taurolithocholic acid[no description available]medium10bile acid taurine conjugate;
monocarboxylic acid amide		human metabolite
flupenthixol[no description available]medium10flupenthixoldopaminergic antagonist
topiramate[no description available]medium10cyclic ketal;
ketohexose derivative;
sulfamate ester		anticonvulsant;
sodium channel blocker
(6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid[no description available]medium10dihydroxy monocarboxylic acid;
indoles;
organofluorine compound
indinavir sulfate[no description available]medium10azaheterocycle sulfate salt
ximelagatran[no description available]medium10amidoxime;
azetidines;
carboxamide;
ethyl ester;
hydroxylamines;
secondary amino compound;
secondary carboxamide;
tertiary carboxamide		anticoagulant;
EC 3.4.21.5 (thrombin) inhibitor;
prodrug;
serine protease inhibitor
ampicillin sodium[no description available]medium10organic sodium salt
mobic[no description available]medium101,3-thiazoles;
benzothiazine;
monocarboxylic acid amide		analgesic;
antirheumatic drug;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
sudoxicam[no description available]medium10
manganese[no description available]medium10elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
potassium iodide[no description available]medium10potassium saltexpectorant;
radical scavenger
iodine[no description available]medium20halide anion;
monoatomic iodine		human metabolite
interleukin-8[no description available]medium10
25-hydroxyvitamin d 2[no description available]medium10hydroxycalciol;
seco-ergostane;
vitamin D		bone density conservation agent;
human xenobiotic metabolite;
nutraceutical
bryostatin 1[no description available]medium10
glutamic acid[no description available]medium200glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical
cyclosporine[no description available]medium20
cholecalciferol[no description available]medium10D3 vitamins;
hydroxy seco-steroid;
seco-cholestane;
secondary alcohol;
steroid hormone		geroprotector;
human metabolite
4-aminopyridine[no description available]medium170aminopyridine;
aromatic amine		avicide;
orphan drug;
potassium channel blocker
ovalbumin[no description available]medium20
gentamicin[no description available]medium10
ethidium[no description available]medium40phenanthridinesfluorochrome;
intercalator
mefloquine[no description available]medium201
adamantane[no description available]medium20adamantanes;
polycyclic alkane
oxidopamine[no description available]medium10benzenetriol;
catecholamine;
primary amino compound		drug metabolite;
human metabolite;
neurotoxin
cytarabine[no description available]medium10beta-D-arabinoside;
monosaccharide derivative;
pyrimidine nucleoside		antimetabolite;
antineoplastic agent;
antiviral agent;
immunosuppressive agent
ginsenoside rg1[no description available]medium1012beta-hydroxy steroid;
3beta-hydroxy-4,4-dimethylsteroid;
beta-D-glucoside;
ginsenoside;
tetracyclic triterpenoid		neuroprotective agent;
pro-angiogenic agent
ginsenosides[no description available]medium10
hydrogen sulfide[no description available]medium10gas molecular entity;
hydracid;
mononuclear parent hydride;
sulfur hydride		Escherichia coli metabolite;
genotoxin;
metabolite;
signalling molecule;
toxin;
vasodilator agent
sodium bisulfide[no description available]medium10
cardiovascular agents[no description available]medium20
chitosan[no description available]medium10
chlorine[no description available]medium111halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
yo-pro 1[no description available]medium30
meclofenamic acid[no description available]medium80aminobenzoic acid;
organochlorine compound;
secondary amino compound		analgesic;
anticonvulsant;
antineoplastic agent;
antipyretic;
antirheumatic drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
benzoxazoles[no description available]medium301,3-benzoxazoles;
mancude organic heterobicyclic parent
gliclazide[no description available]medium160
inositol 1,4,5-trisphosphate[no description available]medium20myo-inositol trisphosphatemouse metabolite
1,2-bis(2-aminophenoxy)ethane-n,n,n',n'-tetraacetic acid[no description available]medium20polyamino carboxylic acid;
tetracarboxylic acid		chelator
egtazic acid[no description available]medium70diether;
tertiary amino compound;
tetracarboxylic acid		chelator
tetrodotoxin[no description available]medium160azatetracycloalkane;
oxatetracycloalkane;
quinazoline alkaloid		animal metabolite;
bacterial metabolite;
marine metabolite;
neurotoxin;
voltage-gated sodium channel blocker
propidium[no description available]medium50phenanthridines;
quaternary ammonium ion		fluorochrome;
intercalator
gamma-aminobutyric acid[no description available]medium110amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid		human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule
urethane[no description available]medium10carbamate esterfungal metabolite;
mutagen
2-aminoadipic acid[no description available]medium10amino dicarboxylic acid;
dicarboxylic fatty acid;
non-proteinogenic alpha-amino acid		Caenorhabditis elegans metabolite;
mammalian metabolite
minocycline[no description available]medium40
sb 225002[no description available]medium10nitrophenol
natriuretic peptide, c-type[no description available]medium20
pqq cofactor[no description available]medium10orthoquinones;
pyrroloquinoline cofactor;
tricarboxylic acid		anti-inflammatory agent;
antioxidant;
cofactor;
water-soluble vitamin (role)
nicotine[no description available]medium303-(1-methylpyrrolidin-2-yl)pyridineanxiolytic drug;
biomarker;
immunomodulator;
mitogen;
neurotoxin;
nicotinic acetylcholine receptor agonist;
peripheral nervous system drug;
phytogenic insecticide;
plant metabolite;
psychotropic drug;
teratogenic agent;
xenobiotic
iodoacetic acid[no description available]medium10haloacetic acid;
organoiodine compound		alkylating agent
cytochrome c-t[no description available]medium40
pentylenetetrazole[no description available]medium40organic heterobicyclic compound;
organonitrogen heterocyclic compound
corticosterone[no description available]medium51011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
5-methylpyrazole-3-carboxylic acid[no description available]medium10monocarboxylic acid;
pyrazoles		metabolite
phenyl-n-tert-butylnitrone[no description available]medium10
tert-butylhydroperoxide[no description available]medium10alkyl hydroperoxideantibacterial agent;
oxidising agent
a 967079[no description available]medium10
leptin[no description available]medium40
salvianolic acid B[no description available]medium101-benzofurans;
catechols;
dicarboxylic acid;
enoate ester;
polyphenol		anti-inflammatory agent;
antidepressant;
antineoplastic agent;
antioxidant;
apoptosis inducer;
autophagy inhibitor;
cardioprotective agent;
hepatoprotective agent;
hypoglycemic agent;
neuroprotective agent;
osteogenesis regulator;
plant metabolite
benzofurans[no description available]medium10
heptanol[no description available]medium130heptanol;
primary alcohol		flavouring agent;
fragrance;
gap junctional intercellular communication inhibitor;
plant metabolite
2-aminoethoxydiphenyl borate[no description available]medium30organoboron compound;
primary amino compound		calcium channel blocker;
IP3 receptor antagonist;
potassium channel opener
lucifer yellow[no description available]medium160organic lithium saltfluorochrome
carbachol[no description available]medium50ammonium salt;
carbamate ester		cardiotonic drug;
miotic;
muscarinic agonist;
nicotinic acetylcholine receptor agonist;
non-narcotic analgesic
y 27632[no description available]medium30aromatic amide
isoproterenol[no description available]medium30catechols;
secondary alcohol;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent
palmidrol[no description available]medium10endocannabinoid;
N-(long-chain-acyl)ethanolamine;
N-(saturated fatty acyl)ethanolamine		anti-inflammatory drug;
anticonvulsant;
antihypertensive agent;
neuroprotective agent
anandamide[no description available]medium10endocannabinoid;
N-acylethanolamine 20:4		human blood serum metabolite;
neurotransmitter;
vasodilator agent
trimethylamine[no description available]medium70methylamines;
tertiary amine		Escherichia coli metabolite;
human xenobiotic metabolite
1-octanol[no description available]medium80octanol;
primary alcohol		antifungal agent;
bacterial metabolite;
fuel additive;
kairomone;
plant metabolite
suramin[no description available]medium60naphthalenesulfonic acid;
phenylureas;
secondary carboxamide		angiogenesis inhibitor;
antinematodal drug;
antineoplastic agent;
apoptosis inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
GABA antagonist;
GABA-gated chloride channel antagonist;
purinergic receptor P2 antagonist;
ryanodine receptor agonist;
trypanocidal drug
brefeldin a[no description available]medium30macrolide antibioticPenicillium metabolite
adenosine diphosphate[no description available]medium10adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite;
human metabolite
pyridoxal phosphate[no description available]medium70methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6 phosphate		coenzyme;
cofactor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
mrs 2211[no description available]medium10
alpha-synuclein[no description available]medium20
fibric acid[no description available]medium10
verapamil[no description available]medium40aromatic ether;
nitrile;
polyether;
tertiary amino compound
ouabain[no description available]medium4011alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone		anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite
bethanechol[no description available]medium10carbamate ester;
quaternary ammonium ion		muscarinic agonist
glycyrrhizic acid[no description available]medium270enone;
glucosiduronic acid;
pentacyclic triterpenoid;
tricarboxylic acid;
triterpenoid saponin		EC 3.4.21.5 (thrombin) inhibitor;
plant metabolite
metyrapone[no description available]medium30aromatic ketoneantimetabolite;
diagnostic agent;
EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor
morphine[no description available]medium31morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic
glyburide[no description available]medium50monochlorobenzenes;
N-sulfonylurea		anti-arrhythmia drug;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor;
hypoglycemic agent
arachidonic acid[no description available]medium40icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid		Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite
spermine[no description available]medium20polyazaalkane;
tetramine		antioxidant;
fundamental metabolite;
immunosuppressive agent
uridine triphosphate[no description available]medium60pyrimidine ribonucleoside 5'-triphosphate;
uridine 5'-phosphate		Escherichia coli metabolite;
mouse metabolite
alpha,beta-methyleneadenosine 5'-triphosphate[no description available]medium10nucleoside triphosphate analogue
2',3'-dialdehyde atp[no description available]medium10
1,2-bis(2-aminophenoxy)ethane n,n,n',n'-tetraacetic acid acetoxymethyl ester[no description available]medium40
6-methyl-2-(phenylethynyl)pyridine[no description available]medium30acetylenic compound;
methylpyridines		anxiolytic drug;
metabotropic glutamate receptor antagonist
ng-nitroarginine methyl ester[no description available]medium100alpha-amino acid ester;
L-arginine derivative;
methyl ester;
N-nitro compound		EC 1.14.13.39 (nitric oxide synthase) inhibitor
bradykinin[no description available]medium80oligopeptidehuman blood serum metabolite;
vasodilator agent
15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid[no description available]medium40
tram 34[no description available]medium30organochlorine compound
etomidate[no description available]medium10ethyl ester;
imidazoles		intravenous anaesthetic;
sedative
fluorexon[no description available]medium50xanthene dyefluorochrome
loperamide[no description available]medium10monocarboxylic acid amide;
monochlorobenzenes;
piperidines;
tertiary alcohol		anticoronaviral agent;
antidiarrhoeal drug;
mu-opioid receptor agonist
erythrosine[no description available]medium70
tannins[no description available]medium10
hydrochloric acid[no description available]medium20chlorine molecular entity;
gas molecular entity;
hydrogen halide;
mononuclear parent hydride		mouse metabolite
11-ketotestosterone[no description available]medium1011-oxo steroid;
17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen;
human metabolite;
marine xenobiotic metabolite
citrulline[no description available]medium20amino acid zwitterion;
citrulline		Daphnia magna metabolite;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
protective agent;
Saccharomyces cerevisiae metabolite
lead[no description available]medium10carbon group element atom;
elemental lead;
metal atom		neurotoxin
protoporphyrin ix[no description available]medium10
pituitrin[no description available]medium20
Brilliant Blue[no description available]medium30organic molecular entity
gadolinium[no description available]medium40f-block element atom;
lanthanoid atom
triazoles[no description available]medium101,2,3-triazole
isoxazoles[no description available]medium10isoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid[no description available]medium60arenesulfonic acid;
azobenzenes;
methylpyridines;
monohydroxypyridine;
organic phosphate;
pyridinecarbaldehyde		purinergic receptor P2X antagonist
oleylamide[no description available]medium30primary fatty amidehuman metabolite;
plant metabolite
thromboplastin[no description available]medium10
angiotensin ii[no description available]medium70amino acid zwitterion;
angiotensin II		human metabolite
rotigaptide[no description available]medium30
colforsin[no description available]medium100acetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol		adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist
iberiotoxin[no description available]medium10
oxadiazoles[no description available]medium10
quinoxalines[no description available]medium20mancude organic heterobicyclic parent;
naphthyridine;
ortho-fused heteroarene
1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one[no description available]medium10oxadiazoloquinoxalineEC 4.6.1.2 (guanylate cyclase) inhibitor
sulforhodamine 101[no description available]medium30organic heteroheptacyclic compoundfluorochrome
bortezomib[no description available]medium10amino acid amide;
L-phenylalanine derivative;
pyrazines		antineoplastic agent;
antiprotozoal drug;
protease inhibitor;
proteasome inhibitor
ro13-9904[no description available]medium10
phenylephrine[no description available]medium70phenols;
phenylethanolamines;
secondary amino compound		alpha-adrenergic agonist;
cardiotonic drug;
mydriatic agent;
nasal decongestant;
protective agent;
sympathomimetic agent;
vasoconstrictor agent
niflumic acid[no description available]medium30aromatic carboxylic acid;
pyridines
5-nitro-2-(3-phenylpropylamino)benzoic acid[no description available]medium40nitrobenzoic acid
3,4-dihydroxyphenylglycol[no description available]medium20catechols;
tetrol		metabolite;
mouse metabolite
methoxyhydroxyphenylglycol[no description available]medium20methoxybenzenes;
phenols
arl-67156[no description available]medium20
sr 95531[no description available]medium60methoxybenzenes
methyllycaconitine[no description available]medium10
aconitine[no description available]medium10
oleic acid[no description available]medium10octadec-9-enoic acidantioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent
c.i. 42510[no description available]medium20
coomassie brilliant blue[no description available]medium20
cortisone[no description available]medium30511-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
gold[no description available]medium10copper group element atom;
elemental gold
1,3-dipropyl-8-cyclopentylxanthine[no description available]medium10oxopurineadenosine A1 receptor antagonist;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor
cyclic gmp[no description available]medium303',5'-cyclic purine nucleotide;
guanyl ribonucleotide		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one[no description available]medium10chromones;
morpholines;
organochlorine compound		autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector
ammonium hydroxide[no description available]medium10azane;
gas molecular entity;
mononuclear parent hydride		EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant
cobalt[no description available]medium50cobalt group element atom;
metal allergen		micronutrient
cobaltous chloride[no description available]medium10cobalt salt;
inorganic chloride		allergen;
calcium channel blocker;
sensitiser;
two-colour indicator
proline[no description available]medium10amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid		algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
buthionine sulfoximine[no description available]medium20diastereoisomeric mixture;
homocysteines;
non-proteinogenic alpha-amino acid;
sulfoximide		EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor;
ferroptosis inducer
1-methyl-3-isobutylxanthine[no description available]medium103-isobutyl-1-methylxanthine
kainic acid[no description available]medium40dicarboxylic acid;
L-proline derivative;
non-proteinogenic L-alpha-amino acid;
pyrrolidinecarboxylic acid		antinematodal drug;
excitatory amino acid agonist
bafilomycin a1[no description available]medium10cyclic hemiketal;
macrolide antibiotic;
oxanes		apoptosis inducer;
autophagy inhibitor;
bacterial metabolite;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor;
ferroptosis inhibitor;
fungicide;
potassium ionophore;
toxin
atropine[no description available]medium71
taurine[no description available]medium20amino sulfonic acid;
zwitterion		antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite
apyrase[no description available]medium50
trilostane[no description available]medium1017beta-hydroxy steroid;
3-hydroxy steroid;
androstanoid;
epoxy steroid;
nitrile		abortifacient;
antineoplastic agent;
EC 1.1.1.210 [3beta(or 20alpha)-hydroxysteroid dehydrogenase] inhibitor
dihydrotestosterone[no description available]medium1017beta-hydroxy steroid;
17beta-hydroxyandrostan-3-one;
3-oxo-5alpha-steroid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
acrolein[no description available]medium10enalherbicide;
human xenobiotic metabolite;
toxin
deoxyglucose[no description available]medium10
mifepristone[no description available]medium903-oxo-Delta(4) steroid;
acetylenic compound;
tertiary amino compound		abortifacient;
contraceptive drug;
hormone antagonist;
synthetic oral contraceptive
oxymatrine[no description available]medium20
1-(5-isoquinolinesulfonyl)-2-methylpiperazine[no description available]medium30isoquinolines;
N-sulfonylpiperazine		EC 2.7.11.13 (protein kinase C) inhibitor
3'-o-(4-benzoyl)benzoyladenosine 5'-triphosphate[no description available]medium50purine ribonucleoside triphosphate
kn 62[no description available]medium20piperazines
calcimycin[no description available]medium40benzoxazole
3,17-diacetoxyestra-1,3,5(10)-trien-2-carboxylic acid[no description available]medium10
endothelin-1[no description available]medium50
diazooxonorleucine[no description available]medium30amino acid zwitterion;
diazo compound;
ketone;
non-proteinogenic L-alpha-amino acid		analgesic;
antibacterial agent;
antimetabolite;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
bacterial metabolite;
EC 2.4.2.14 (amidophosphoribosyltransferase) inhibitor;
EC 3.5.1.2 (glutaminase) inhibitor;
EC 6.3.4.2 [CTP synthase (glutamine hydrolyzing)] inhibitor;
EC 6.3.5.1 [NAD(+) synthase (glutamine-hydrolysing)] inhibitor;
EC 6.3.5.2 [GMP synthase (glutamine-hydrolysing)] inhibitor;
EC 6.3.5.3 (phosphoribosylformylglycinamidine synthase) inhibitor;
EC 6.3.5.4 [asparagine synthase (glutamine-hydrolysing)] inhibitor;
EC 6.3.5.5 [carbamoyl-phosphate synthase (glutamine-hydrolysing)] inhibitor;
glutamine antagonist
oleanane[no description available]medium10terpenoid fundamental parent;
triterpene
ursane[no description available]medium10terpenoid fundamental parent;
triterpene
oleanolic acid[no description available]medium20hydroxy monocarboxylic acid;
pentacyclic triterpenoid		plant metabolite
modafinil[no description available]medium10monocarboxylic acid amide;
sulfoxide
gossypol[no description available]medium10
glutaminase[no description available]medium20
cesium[no description available]medium30alkali metal atom
cesium chloride[no description available]medium20inorganic caesium salt;
inorganic chloride		phase-transfer catalyst;
vasoconstrictor agent
halothane[no description available]medium80haloalkane;
organobromine compound;
organochlorine compound;
organofluorine compound		inhalation anaesthetic
naloxone[no description available]medium10morphinane alkaloid;
organic heteropentacyclic compound;
tertiary alcohol		antidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist
chlorhexidine[no description available]medium10biguanides;
monochlorobenzenes		antibacterial agent;
antiinfective agent
barium[no description available]medium40alkaline earth metal atom;
elemental barium
barium chloride[no description available]medium20barium salt;
inorganic chloride		potassium channel blocker
thiazolyl blue[no description available]medium20organic bromide saltcolorimetric reagent;
dye
thiazoles[no description available]medium301,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
ethylmaleimide[no description available]medium40maleimidesanticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor
2-amino-5-phosphonovalerate[no description available]medium60non-proteinogenic alpha-amino acidNMDA receptor antagonist
piperidines[no description available]medium50
6-cyano-7-nitroquinoxaline-2,3-dione[no description available]medium70quinoxaline derivative
tubocurarine[no description available]medium20bisbenzylisoquinoline alkaloiddrug allergen;
muscle relaxant;
nicotinic antagonist
2,2,6,6-tetramethylpiperidin-4-yl heptanoate[no description available]medium10fatty acid ester
acetic acid[no description available]medium20monocarboxylic acidantimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent
1,9-dideoxyforskolin[no description available]medium10acetate ester;
labdane diterpenoid;
organic heterotricyclic compound		plant metabolite
fluorocitrate[no description available]medium30carbonyl compound
aspartic acid[no description available]medium50aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
zd 7288[no description available]medium10
gastrins[no description available]medium115
sphingosine[no description available]medium10sphing-4-eninehuman metabolite;
mouse metabolite
sphingosine 1-phosphate[no description available]medium10sphingoid 1-phosphatemouse metabolite;
signalling molecule;
sphingosine-1-phosphate receptor agonist;
T-cell proliferation inhibitor;
vasodilator agent
bromodeoxyuridine[no description available]medium20pyrimidine 2'-deoxyribonucleosideantimetabolite;
antineoplastic agent
4,4'-diisothiocyanostilbene-2,2'-disulfonic acid[no description available]medium20
calcitriol[no description available]medium20D3 vitamins;
hydroxycalciol;
triol		antineoplastic agent;
antipsoriatic;
bone density conservation agent;
calcium channel agonist;
calcium channel modulator;
hormone;
human metabolite;
immunomodulator;
metabolite;
mouse metabolite;
nutraceutical
epidermal growth factor[no description available]medium30
tetradecanoylphorbol acetate[no description available]medium40acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester		antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator
pectins[no description available]medium10D-galactopyranuronic acid
hexamidine[no description available]medium10aromatic ether;
guanidines;
polyether		antimicrobial agent;
antiseptic drug
sodium glutamate[no description available]medium10monosodium glutamateflavouring agent
iloprost[no description available]medium30carbobicyclic compound;
monocarboxylic acid;
secondary alcohol		platelet aggregation inhibitor;
vasodilator agent
muscimol[no description available]medium10alkaloid;
isoxazoles;
primary amino compound		fungal metabolite;
GABA agonist;
oneirogen;
psychotropic drug
methacholine chloride[no description available]medium30quaternary ammonium salt
fasudil[no description available]medium10isoquinolines;
N-sulfonyldiazepane		antihypertensive agent;
calcium channel blocker;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
geroprotector;
neuroprotective agent;
nootropic agent;
vasodilator agent
ryanodine[no description available]medium10
chelerythrine[no description available]medium10benzophenanthridine alkaloid;
organic cation		antibacterial agent;
antineoplastic agent;
EC 2.7.11.13 (protein kinase C) inhibitor
tetraethylammonium[no description available]medium40quaternary ammonium ion
8-bromocyclic gmp[no description available]medium103',5'-cyclic purine nucleotide;
organobromine compound		muscle relaxant;
protein kinase G agonist
bay-k-8644[no description available]medium10(trifluoromethyl)benzenes;
C-nitro compound;
dihydropyridine;
methyl ester
8-bromo cyclic adenosine monophosphate[no description available]medium203',5'-cyclic purine nucleotide;
adenyl ribonucleotide;
organobromine compound		antidepressant;
protein kinase agonist
lysine[no description available]medium40aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid		algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
biocytin[no description available]medium40azabicycloalkane;
L-alpha-amino acid zwitterion;
L-lysine derivative;
monocarboxylic acid amide;
non-proteinogenic L-alpha-amino acid;
thiabicycloalkane;
ureas		mouse metabolite
pregnenolone sulfate[no description available]medium10steroid sulfateEC 2.7.1.33 (pantothenate kinase) inhibitor;
human metabolite
pregnenolone[no description available]medium2020-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
C21-steroid		human metabolite;
mouse metabolite
2-amino-7-phosphonoheptanoic acid[no description available]medium10
fg 9041[no description available]medium10quinoxaline derivative
glycine[no description available]medium40alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
piracetam[no description available]medium10organonitrogen compound;
organooxygen compound
levetiracetam[no description available]medium10pyrrolidin-2-onesanticonvulsant;
environmental contaminant;
xenobiotic
11-cis-retinal[no description available]medium10retinalchromophore;
human metabolite;
mouse metabolite
levamisole[no description available]medium106-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazoleantinematodal drug;
antirheumatic drug;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
immunological adjuvant;
immunomodulator
aldosterone[no description available]medium43311beta-hydroxy steroid;
18-oxo steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
mineralocorticoid;
primary alpha-hydroxy ketone;
steroid aldehyde		human metabolite;
mouse metabolite
atrial natriuretic factor[no description available]medium10polypeptide
natriuretic peptide, brain[no description available]medium10polypeptide
am 251[no description available]medium10amidopiperidine;
carbohydrazide;
dichlorobenzene;
organoiodine compound;
pyrazoles		antidepressant;
antineoplastic agent;
apoptosis inducer;
CB1 receptor antagonist
alpha-methyl-4-carboxyphenylglycine[no description available]medium10non-proteinogenic alpha-amino acidmetabotropic glutamate receptor antagonist
fura-2[no description available]medium10
papaverine[no description available]medium10benzylisoquinoline alkaloid;
dimethoxybenzene;
isoquinolines		antispasmodic drug;
vasodilator agent
mannitol[no description available]medium10mannitolallergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent
gadolinium chloride[no description available]medium20gadolinium coordination entityTRP channel blocker
histamine[no description available]medium60aralkylamino compound;
imidazoles		human metabolite;
mouse metabolite;
neurotransmitter
u 62840[no description available]medium10carbotricyclic compound;
carboxylic acid		antihypertensive agent;
cardiovascular drug;
human blood serum metabolite;
platelet aggregation inhibitor;
vasodilator agent;
vitamin K antagonist
ns 309[no description available]medium10
duloxetine hydrochloride[no description available]medium10duloxetine hydrochlorideantidepressant
sucrose[no description available]medium10glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
thiophenes[no description available]medium10mancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound		non-polar solvent
e 4031[no description available]medium10sulfonamide
histidine[no description available]medium10amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
quinacrine[no description available]medium10acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound		antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
cytidine triphosphate[no description available]medium10cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite
glycidyl nitrate[no description available]medium10
fenclonine[no description available]medium10phenylalanine derivative
spermidine[no description available]medium10polyazaalkane;
triamine		autophagy inducer;
fundamental metabolite;
geroprotector
omeprazole[no description available]medium70aromatic ether;
benzimidazoles;
pyridines;
sulfoxide
chlorogenic acid[no description available]medium10cinnamate ester;
tannin		food component;
plant metabolite
estrone sulfate[no description available]medium1017-oxo steroid;
steroid sulfate		human metabolite;
mouse metabolite
ucph 101[no description available]medium10
glycogen[no description available]medium20
cariporide[no description available]medium10
hydrogen carbonate[no description available]medium162carbon oxoanioncofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose[no description available]medium10gallate ester;
galloyl beta-D-glucose		anti-inflammatory agent;
antineoplastic agent;
geroprotector;
hepatoprotective agent;
plant metabolite;
radiation protective agent;
radical scavenger
sr141716[no description available]medium10amidopiperidine;
carbohydrazide;
dichlorobenzene;
monochlorobenzenes;
pyrazoles		anti-obesity agent;
appetite depressant;
CB1 receptor antagonist
palmitoleic acid[no description available]medium10hexadec-9-enoic acidalgal metabolite;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
human blood serum metabolite
sodium propionate[no description available]medium10organic sodium saltantifungal drug;
food preservative
ammonium chloride[no description available]medium10ammonium salt;
inorganic chloride		ferroptosis inhibitor
propionic acid[no description available]medium10saturated fatty acid;
short-chain fatty acid		antifungal drug
choline[no description available]medium10cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
hydroxocobalamin[no description available]medium10
apomorphine[no description available]medium20aporphine alkaloidalpha-adrenergic drug;
antidyskinesia agent;
antiparkinson drug;
dopamine agonist;
emetic;
serotonergic drug
furazolidone[no description available]medium10nitrofuran antibiotic;
oxazolidines		antibacterial drug;
antiinfective agent;
antitrichomonal drug;
EC 1.4.3.4 (monoamine oxidase) inhibitor
berberine[no description available]medium10alkaloid antibiotic;
berberine alkaloid;
botanical anti-fungal agent;
organic heteropentacyclic compound		antilipemic drug;
antineoplastic agent;
antioxidant;
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor;
EC 1.21.3.3 (reticuline oxidase) inhibitor;
EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
EC 3.1.1.4 (phospholipase A2) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
hypoglycemic agent;
metabolite;
potassium channel blocker
mercuric chloride[no description available]medium10mercury coordination entitysensitiser
desoxycorticosterone[no description available]medium6020-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
mineralocorticoid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
eplerenone[no description available]medium103-oxo-Delta(4) steroid;
epoxy steroid;
gamma-lactone;
methyl ester;
organic heteropentacyclic compound;
oxaspiro compound;
steroid acid ester		aldosterone antagonist;
antihypertensive agent
7-hydroxydehydroepiandrosterone[no description available]medium1017-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
7alpha-hydroxy steroid;
androstanoid		anti-inflammatory agent;
antioxidant;
estrogen;
human xenobiotic metabolite;
rat metabolite
dehydroepiandrosterone[no description available]medium2017-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
androstanoid		androgen;
human metabolite;
mouse metabolite
nad[no description available]medium80organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
nadp[no description available]medium70
7-oxodehydroepiandrosterone[no description available]medium1017-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
7-oxo steroid;
androstanoid		human blood serum metabolite;
nutraceutical;
prohormone
potassium chloride[no description available]medium40inorganic chloride;
inorganic potassium salt;
potassium salt		fertilizer
lanthanum[no description available]medium30f-block element atom;
lanthanoid atom;
scandium group element atom
fluorides[no description available]medium10halide anion;
monoatomic fluorine
bicuculline[no description available]medium70benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines		agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin
valine[no description available]medium10L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
cgp 55845a[no description available]medium20
tetramethylrhodamine[no description available]medium20xanthene dye
bicuculline methiodide[no description available]medium20
hydrogen[no description available]medium10elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
diethylstilbestrol[no description available]medium10olefinic compound;
polyphenol		antifungal agent;
antineoplastic agent;
autophagy inducer;
calcium channel blocker;
carcinogenic agent;
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
endocrine disruptor;
xenoestrogen
estriol[no description available]medium1016alpha-hydroxy steroid;
17beta-hydroxy steroid;
3-hydroxy steroid		estrogen;
human metabolite;
human xenobiotic metabolite;
mouse metabolite
pepstatin[no description available]medium10pentapeptide;
secondary carboxamide		bacterial metabolite;
EC 3.4.23.* (aspartic endopeptidase) inhibitor
dizocilpine maleate[no description available]medium40maleate salt;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
sevoflurane[no description available]medium10ether;
organofluorine compound		central nervous system depressant;
inhalation anaesthetic;
platelet aggregation inhibitor
xanthenes[no description available]medium20xanthene
picrotoxin[no description available]medium40
fluorescein-5-isothiocyanate[no description available]medium10fluorescein isothiocyanate
solochrome cyanine r[no description available]medium10
pamoic acid[no description available]medium10dicarboxylic acid
2-naphthol[no description available]medium10naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
nitroarginine[no description available]medium30guanidines;
L-arginine derivative;
N-nitro compound;
non-proteinogenic L-alpha-amino acid
baclofen[no description available]medium10amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid;
monochlorobenzenes;
primary amino compound		central nervous system depressant;
GABA agonist;
muscle relaxant
enkephalin, ala(2)-mephe(4)-gly(5)-[no description available]medium10
glycyrrhetyl 3-monoglucuronide[no description available]medium10beta-D-glucosiduronic acid;
enone;
monosaccharide derivative;
oxo dicarboxylic acid;
pentacyclic triterpenoid;
triterpenoid saponin		anti-allergic agent;
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor;
human xenobiotic metabolite;
plant metabolite;
sweetening agent
beta-escin[no description available]medium10
astragaloside a[no description available]medium10
caprylic aldehyde[no description available]medium10medium-chain fatty aldehyde;
n-alkanal;
saturated fatty aldehyde		plant metabolite
11-dehydrocorticosterone[no description available]medium19011-oxo steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
corticosteroid;
primary alpha-hydroxy ketone		human metabolite;
mouse metabolite
ru 28318[no description available]medium60
malondialdehyde[no description available]medium10dialdehydebiomarker
cyclin d1[no description available]medium10
trans-1,4-bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride[no description available]medium10
u 0126[no description available]medium10aryl sulfide;
dinitrile;
enamine;
substituted aniline		antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
osteogenesis regulator;
vasoconstrictor agent
prednisolone[no description available]medium3111beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
drug metabolite;
environmental contaminant;
immunosuppressive agent;
xenobiotic
minoxidil[no description available]medium10dialkylarylamine;
tertiary amino compound
tyrosine[no description available]medium20amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
dinoprostone[no description available]medium210prostaglandins Ehuman metabolite;
mouse metabolite;
oxytocic
osteoprotegerin[no description available]medium10long-chain fatty acid
lanthanum chloride[no description available]medium20
chloroquine[no description available]medium10aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
harmaline[no description available]medium10harmala alkaloidoneirogen
formaldehyde[no description available]medium10aldehyde;
one-carbon compound		allergen;
carcinogenic agent;
disinfectant;
EC 3.5.1.4 (amidase) inhibitor;
environmental contaminant;
Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
cysteine[no description available]medium10cysteiniumfundamental metabolite
eticlopride[no description available]medium10salicylamides
n-methylaspartate[no description available]medium20amino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound		neurotransmitter agent
substance p[no description available]medium10peptideneurokinin-1 receptor agonist;
neurotransmitter;
vasodilator agent
succinic acid[no description available]medium10alpha,omega-dicarboxylic acid;
C4-dicarboxylic acid		anti-ulcer drug;
fundamental metabolite;
micronutrient;
nutraceutical;
radiation protective agent
4-hydroxybutyric acid[no description available]medium104-hydroxy monocarboxylic acid;
hydroxybutyric acid		general anaesthetic;
GHB receptor agonist;
neurotoxin;
sedative
12-hydroxy-5,8,10,14-eicosatetraenoic acid[no description available]medium10
n-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide[no description available]medium10isoquinolines;
sulfonamide
trinitrobenzenesulfonic acid[no description available]medium10arenesulfonic acid;
C-nitro compound		epitope;
explosive;
reagent
mocetinostat[no description available]medium10aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent
pulmicort[no description available]medium1011beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
cyclic acetal;
glucocorticoid;
primary alpha-hydroxy ketone		anti-inflammatory drug;
bronchodilator agent;
drug allergen
bismuth[no description available]medium354metal atom;
pnictogen
aluminum[no description available]medium234boron group element atom;
elemental aluminium;
metal atom
ranitidine[no description available]medium121C-nitro compound;
furans;
organic sulfide;
tertiary amino compound		anti-ulcer drug;
drug allergen;
environmental contaminant;
H2-receptor antagonist;
xenobiotic
sulpiride[no description available]medium31benzamides;
N-alkylpyrrolidine;
sulfonamide		antidepressant;
antiemetic;
antipsychotic agent;
dopaminergic antagonist
trimipramine[no description available]medium72dibenzoazepine;
tertiary amino compound		antidepressant;
environmental contaminant;
xenobiotic
trithiozine[no description available]medium31methoxybenzenes
domperidone[no description available]medium30benzimidazoles;
heteroarylpiperidine		antiemetic;
dopaminergic antagonist
metoclopramide[no description available]medium200benzamides;
monochlorobenzenes;
substituted aniline;
tertiary amino compound		antiemetic;
dopaminergic antagonist;
environmental contaminant;
gastrointestinal drug;
xenobiotic
proglumide[no description available]medium53benzamides;
dicarboxylic acid monoamide;
glutamine derivative;
racemate		anti-ulcer drug;
cholecystokinin antagonist;
cholinergic antagonist;
delta-opioid receptor agonist;
drug metabolite;
gastrointestinal drug;
opioid analgesic;
xenobiotic metabolite
gefarnate[no description available]medium30organic molecular entity
pirenzepine[no description available]medium187pyridobenzodiazepineanti-ulcer drug;
antispasmodic drug;
muscarinic antagonist
albuterol[no description available]medium10phenols;
phenylethanolamines;
secondary amino compound		beta-adrenergic agonist;
bronchodilator agent;
environmental contaminant;
xenobiotic
metiamide[no description available]medium31imidazoles
pyrogastrone[no description available]medium82
benzimidazole[no description available]medium20benzimidazole;
polycyclic heteroarene
bismuth tripotassium dicitrate[no description available]medium131
16,16-dimethylprostaglandin e2[no description available]medium20cyclopentanones;
monocarboxylic acid;
prostanoid;
secondary allylic alcohol		anti-ulcer drug;
gastrointestinal drug;
radiation protective agent
fluprednisolone[no description available]medium20fluorinated steroid
isoflupredone acetate[no description available]medium10corticosteroid hormone
fludrocortisone[no description available]medium4011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
fluorinated steroid;
mineralocorticoid		adrenergic agent;
anti-inflammatory drug
pentagastrin[no description available]medium61organic molecular entity
technetium[no description available]medium10manganese group element atom
sodium pertechnetate tc 99m[no description available]medium10
thromboxane a2[no description available]medium30epoxy monocarboxylic acid;
thromboxanes A		mouse metabolite
thromboxane b2[no description available]medium40thromboxanes Bhuman metabolite;
mouse metabolite
thromboxanes[no description available]medium30
cicloxolone[no description available]medium81
arbaprostil[no description available]medium10prostanoid
1-benzylimidazole[no description available]medium10
triletide[no description available]medium21
sofalcone[no description available]medium20aromatic ether;
chalcones;
monocarboxylic acid		anti-ulcer drug;
antibacterial agent;
gastrointestinal drug;
plant metabolite
chalcone[no description available]medium20chalconeEC 3.2.1.1 (alpha-amylase) inhibitor
cysteamine[no description available]medium20amine;
thiol		geroprotector;
human metabolite;
mouse metabolite;
radiation protective agent
reserpine[no description available]medium10alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic
sch 28080[no description available]medium10imidazopyridine
cyproheptadine[no description available]medium11piperidines;
tertiary amine		anti-allergic agent;
antipruritic drug;
gastrointestinal drug;
H1-receptor antagonist;
serotonergic antagonist
taurocholic acid[no description available]medium10amino sulfonic acid;
bile acid taurine conjugate		human metabolite
phosphatidylcholines[no description available]medium201,2-diacyl-sn-glycero-3-phosphocholine
alginate, aluminium hydroxide, magnesium trisilicate, sodium bicarbonate drug combination[no description available]medium10
thiopropamine[no description available]medium22
amiloride[no description available]medium51aromatic amine;
guanidines;
organochlorine compound;
pyrazines		diuretic;
sodium channel blocker
pyrazines[no description available]medium11diazine;
pyrazines		Daphnia magna metabolite
geranylgeranylacetone[no description available]medium10
retinol[no description available]medium20retinol;
vitamin A		human metabolite;
mouse metabolite;
plant metabolite
glucagon[no description available]medium40peptide hormone
enkephalin, leucine[no description available]medium10pentapeptide;
peptide zwitterion		analgesic;
delta-opioid receptor agonist;
human metabolite;
mu-opioid receptor agonist;
neurotransmitter;
rat metabolite
mequinol[no description available]medium10methoxybenzenes;
phenols		metabolite
azoxymethane[no description available]medium10
6-o-palmitoylascorbic acid[no description available]medium10fatty acid ester
dimethyl fumarate[no description available]medium10diester;
enoate ester;
methyl ester		antipsoriatic;
immunomodulator
fumarates[no description available]medium10butenedioate;
C4-dicarboxylate		human metabolite;
metabolite;
Saccharomyces cerevisiae metabolite
cyanides[no description available]medium10pseudohalide anionEC 1.9.3.1 (cytochrome c oxidase) inhibitor
3,3'-dioctadecylindocarbocyanine[no description available]medium10Cy5 dye;
indolium ion		fluorochrome
carbocyanines[no description available]medium10cyanine dye;
organic iodide salt		fluorochrome
naringin[no description available]medium10(2S)-flavan-4-one;
4'-hydroxyflavanones;
dihydroxyflavanone;
disaccharide derivative;
neohesperidoside		anti-inflammatory agent;
antineoplastic agent;
metabolite
benzamil[no description available]medium10guanidines;
pyrazines
ru-28362[no description available]medium30
cortodoxone[no description available]medium20deoxycortisol;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
quercetin[no description available]medium207-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger
aluminum hydroxide, magnesium hydroxide, drug combination[no description available]medium10
methylnitrosourea[no description available]medium10N-nitrosoureasalkylating agent;
carcinogenic agent;
mutagen;
teratogenic agent
acetylglucosamine[no description available]medium20N-acetyl-D-glucosamineepitope
androstenedione[no description available]medium3017-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
glucuronic acid[no description available]medium10D-glucuronic acidalgal metabolite
prostaglandin a1[no description available]medium10prostaglandins A
bromochloroacetic acid[no description available]medium102-bromocarboxylic acid;
monocarboxylic acid;
organochlorine compound
epinastine[no description available]medium10corticosteroid hormone
androsterone[no description available]medium1017-oxo steroid;
3alpha-hydroxy steroid;
androstanoid;
C19-steroid		androgen;
anticonvulsant;
human blood serum metabolite;
human metabolite;
human urinary metabolite;
mouse metabolite;
pheromone
androstane-3,17-diol[no description available]medium1017-hydroxy steroid;
3-hydroxy steroid;
androstanoid
etiocholanolone[no description available]medium1017-oxo steroid;
3alpha-hydroxy steroid;
androstanoid		human metabolite;
mouse metabolite
androstane-3,17-dione, (5alpha)-isomer[no description available]medium103-oxo-5alpha-steroid;
androstane-3,17-dione		mouse metabolite
sesamol[no description available]medium10benzodioxoles
kynurenic acid[no description available]medium10monohydroxyquinoline;
quinolinemonocarboxylic acid		G-protein-coupled receptor agonist;
human metabolite;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist;
Saccharomyces cerevisiae metabolite
3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid[no description available]medium10
3,5-dihydroxyphenylglycine[no description available]medium10alpha-amino acid
deuterium[no description available]medium11dihydrogen
diacetylfluorescein[no description available]medium10
heparitin sulfate[no description available]medium10
pd 153035[no description available]medium10aromatic amine;
aromatic ether;
bromobenzenes;
quinazolines;
secondary amino compound		EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist
quinazolines[no description available]medium10azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinazolines
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid[no description available]medium10non-proteinogenic alpha-amino acid
deoxyartemisinin[no description available]medium10
artemisinin[no description available]medium10organic peroxide;
sesquiterpene lactone		antimalarial;
plant metabolite
sesquiterpenes[no description available]medium10
lithium[no description available]medium10alkali metal atom
carbodiimides[no description available]medium10carbodiimide
amylopectin[no description available]medium20
cholestyramine resin[no description available]medium40
bucladesine[no description available]medium203',5'-cyclic purine nucleotide
glutamine[no description available]medium21amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
clonidine[no description available]medium10clonidine;
imidazoline
salicylates[no description available]medium20monohydroxybenzoateplant metabolite
chlordiazepoxide[no description available]medium10benzodiazepine
pentobarbital[no description available]medium10barbituratesGABAA receptor agonist
ephedrine[no description available]medium10phenethylamine alkaloid;
phenylethanolamines		bacterial metabolite;
environmental contaminant;
nasal decongestant;
plant metabolite;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
amphetamine[no description available]medium10primary amine
acid phosphatase[no description available]medium10
limestone[no description available]medium10calcium salt;
carbonate salt;
inorganic calcium salt;
one-carbon compound		antacid;
fertilizer;
food colouring;
food firming agent
diazepam[no description available]medium101,4-benzodiazepinone;
organochlorine compound		anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic
propantheline[no description available]medium10xanthenes
carbonates[no description available]medium10carbon oxoanion
chlorthalidone[no description available]medium10isoindoles;
monochlorobenzenes;
sulfonamide
lactulose[no description available]medium10
cholecystokinin[no description available]medium10
vitamin b 12[no description available]medium10
chiniofon[no description available]medium10
bendroflumethiazide[no description available]medium10benzothiadiazine;
sulfonamide		antihypertensive agent;
diuretic
barium sulfate[no description available]medium10barium salt;
inorganic barium salt;
metal sulfate		radioopaque medium
6-ketoprostaglandin f1 alpha[no description available]medium20prostaglandins Falphahuman metabolite;
mouse metabolite
monensin[no description available]medium20cyclic hemiketal;
monocarboxylic acid;
polyether antibiotic;
spiroketal		antifungal agent;
coccidiostat;
ionophore
dinoprost[no description available]medium10monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite
calcium oxalate[no description available]medium10organic calcium salt
linsidomine[no description available]medium10morpholines
molsidomine[no description available]medium10ethyl ester;
morpholines;
oxadiazole;
zwitterion		antioxidant;
apoptosis inhibitor;
cardioprotective agent;
nitric oxide donor;
vasodilator agent
methylene blue[no description available]medium10organic chloride saltacid-base indicator;
antidepressant;
antimalarial;
antimicrobial agent;
antioxidant;
cardioprotective agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 4.6.1.2 (guanylate cyclase) inhibitor;
fluorochrome;
histological dye;
neuroprotective agent;
physical tracer
esculin[no description available]medium10beta-D-glucoside;
hydroxycoumarin		antioxidant;
metabolite
losartan potassium[no description available]medium10
pentacaine[no description available]medium10
carbamates[no description available]medium10amino-acid anion
phenyl acetate[no description available]medium10benzenes;
phenyl acetates
ecabet[no description available]medium20diterpenoid
sincalide[no description available]medium10oligopeptide
trichloroacetic acid[no description available]medium10monocarboxylic acid;
organochlorine compound		carcinogenic agent;
metabolite;
mouse metabolite
allotetrahydrocortisol[no description available]medium10corticosteroid hormone
tetrahydrocortisol[no description available]medium2011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3alpha-hydroxy steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone
tetrahydrocortisone[no description available]medium2021-hydroxy steroid
cycloheximide[no description available]medium10antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor
ru 26988[no description available]medium10
9-fluoroprednisolone[no description available]medium1021-hydroxy steroid
alcian blue[no description available]medium10
esaprazole[no description available]medium20
w 7[no description available]medium10
phosphonoacetic acid[no description available]medium10monocarboxylic acid;
phosphonic acids		antiviral agent;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor
acyclovir[no description available]medium102-aminopurines;
oxopurine		antimetabolite;
antiviral drug
urea[no description available]medium10isourea;
monocarboxylic acid amide;
one-carbon compound		Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
n-acetylneuraminic acid[no description available]medium11N-acetylneuraminic acidsantioxidant;
bacterial metabolite;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
human metabolite;
mouse metabolite
masoprocol[no description available]medium20nordihydroguaiaretic acidantineoplastic agent;
hypoglycemic agent;
lipoxygenase inhibitor;
metabolite
peoniflorin[no description available]medium10
glucose, (beta-d)-isomer[no description available]medium10D-glucopyranoseepitope;
mouse metabolite
glycosides[no description available]medium10
rubidium[no description available]medium10alkali metal atom
acetylglycyrrhetinic acid[no description available]medium10triterpenoid
iopanoic acid[no description available]medium10monocarboxylic acid
sulfadiazine[no description available]medium10pyrimidines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antiinfective agent;
antimicrobial agent;
antiprotozoal drug;
coccidiostat;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
xenobiotic
eye[no description available]medium20
guaifenesin[no description available]medium151methoxybenzenes
fomesafen[no description available]medium30aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-sulfonylcarboxamide;
organofluorine compound;
phenols		agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
s,n,n'-tripropylthiocarbamate[no description available]medium10tertiary amine
iodinated glycerol[no description available]medium4510dioxolane
ursolic acid[no description available]medium10hydroxy monocarboxylic acid;
pentacyclic triterpenoid		geroprotector;
plant metabolite
nociceptin[no description available]medium10organic molecular entity;
polypeptide		human metabolite;
rat metabolite
inositol 3-phosphate[no description available]medium10
digitoxin[no description available]medium10cardenolide glycosideEC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor
acetic acid (3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f][1]benzopyran-5-yl) ester[no description available]low00triterpenoid
medicagenic acid[no description available]low00triterpenoid
quassin[no description available]low00triterpenoid
neoquassin[no description available]low00triterpenoid
chaparrinone[no description available]low00triterpenoid
Tormentic acid[no description available]low00triterpenoidmetabolite
echinocystic acid[no description available]low00triterpenoid
brusatol[no description available]low00triterpenoid
betulinic acid methyl ester[no description available]low00triterpenoid
hecogenin[no description available]low00triterpenoid
beta-amyrin acetate[no description available]low00triterpenoid
lupenone[no description available]low00triterpenoidmetabolite
uvaol[no description available]low00triterpenoidmetabolite
isobrucein b[no description available]low00triterpenoid
Lup-20(29)-en-28-al, 3beta-hydroxy-[no description available]low00triterpenoid
hecogenin acetate[no description available]low00triterpenoid
betulonic acid[no description available]low00triterpenoidanticoronaviral agent
bruceine b[no description available]low00triterpenoid
boswellic acid[no description available]low00triterpenoid
maytenonic acid[no description available]low00triterpenoidmetabolite
cylindrin[no description available]low00triterpenoid
pomolic acid[no description available]low00triterpenoidmetabolite
euphol[no description available]low00triterpenoid
chaparrin[no description available]low00triterpenoid
glaucarubolone[no description available]low00triterpenoid
deltonin[no description available]low00triterpenoid
gitogenin[no description available]low00triterpenoid
ruscogenin[no description available]low00triterpenoid
yamogenin[no description available]low00triterpenoid
cyclamin[no description available]low00triterpenoid
beta-hederin[no description available]low00triterpenoid
absynthin[no description available]low00organic heteroheptacyclic compound;
sesquiterpene lactone;
triterpenoid		anti-inflammatory agent;
plant metabolite
ganoderic acid a[no description available]low00triterpenoid
ganoderiol f[no description available]low00triterpenoid
Ganodermanontriol[no description available]low00triterpenoidmetabolite
(4As,6aS,6bR,10S,12aR)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid[no description available]low00triterpenoid
betulafolientriol[no description available]low00triterpenoid
lupeol, (3alpha)-isomer[no description available]low00triterpenoid
bruceantin[no description available]low00triterpenoid
gamma-oryzanol[no description available]low00triterpenoid
pachymic acid[no description available]low00triterpenoid
masticadienonic acid[no description available]low00triterpenoid
pyracrenic acid[no description available]low00triterpenoidmetabolite
diatoxanthin[no description available]low00triterpenoid
diadinoxanthin[no description available]low00triterpenoid
3 beta-o-acetylursolic acid[no description available]low00triterpenoid
corosolic acid[no description available]low00triterpenoidmetabolite
3-oxo-12-ursen-28-oic acid[no description available]low00triterpenoid
actein[no description available]low00triterpenoidmetabolite
betulone[no description available]low00triterpenoidmetabolite
3-Epikatonic acid[no description available]low00triterpenoid
26-deoxyactein[no description available]low00triterpenoidmetabolite
allobetulinol[no description available]low00cyclic ether;
secondary alcohol;
triterpenoid
acetyl-11-ketoboswellic acid[no description available]low00triterpenoid
alpha-onocerin[no description available]low00diol;
olefinic compound;
secondary alcohol;
triterpenoid		plant metabolite
pulsatilla saponin d[no description available]low00triterpenoidmetabolite
3-epioleanolic acid[no description available]low00triterpenoidmetabolite
11-deoxy glycyrrhetinic acid[no description available]low00triterpenoid
trametenolic acid b[no description available]low00triterpenoid
okenone[no description available]low00carotenoid chi-end group;
triterpenoid
rutundic acid[no description available]low00triterpenoidmetabolite
cauloside c[no description available]low00triterpenoid
taraxasteryl acetate[no description available]low00triterpenoidmetabolite
ganodermic acid s[no description available]low00triterpenoid
Mangiferonic acid[no description available]low00triterpenoid
alisol b monoacetate[no description available]low00triterpenoid
lucidenic acid a[no description available]low00triterpenoid
alisol b[no description available]low00triterpenoid
(3S,4aR,6aR,6bR,8aS,11S,12aS,14bS)-11-(hydroxymethyl)-4,4,6a,6b,8a,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-3,14-diol[no description available]low00triterpenoid
arjunic acid[no description available]low00triterpenoid
methyl lucidenate f[no description available]low00triterpenoid
23-epi-26-deoxyactein[no description available]low00triterpenoidmetabolite
23-hydroxybetulinic acid[no description available]low00triterpenoidmetabolite
ganoderic acid f[no description available]low00triterpenoid
Bridgesigenin A[no description available]low00triterpenoid
jujuboside b[no description available]low00triterpenoid
beta-Elemonic acid[no description available]low00triterpenoid
marneral[no description available]low00aldehyde;
triterpenoid
jujuboside a[no description available]low00triterpenoid
shizukaol B[no description available]low00triterpenoidmetabolite
shizukaol f[no description available]low00triterpenoidmetabolite
ganoderic acid c2[no description available]low00triterpenoid
ganoderic acid y[no description available]low00triterpenoid
lancifodilactone g[no description available]low00cyclic ether;
diol;
enol;
gamma-lactone;
oxaspiro compound;
triterpenoid		anti-HIV agent;
metabolite
shizukaol d[no description available]low00triterpenoidmetabolite
ambrein[no description available]low00tertiary alcohol;
triterpenoid		hypoglycemic agent;
mammalian metabolite
bacoside a3[no description available]low00triterpenoid
ConditionIndicatedRelationship StrengthStudiesTrials
A-V Dissociation0low10
Abortion, Spontaneous0low10
Abortion, Tubal0low10
Absence Seizure0low130
Absence Seizure Disorder0low40
Absence Seizures0low130
Absence Status0low10
Ache0medium112
Achlorhydria0low10
Achylia Gastrica0low10
Acquired Immune Deficiency Syndrome0low20
Acquired Immuno-Deficiency Syndrome0low20
Acquired Immunodeficiency Syndrome0low20
Acquired-Immune Deficiency Syndrome Dementia Complex0low10
ACTH Syndrome, Ectopic0low10
ACTH-Producing Pituitary Adenoma0low10
ACTH-Secreting Pituitary Adenoma0low10
Active Hyperemia0low10
Acute Brain Injuries0low80
Acute Confusional Senile Dementia0low60
Acute Disease0low20
Acute Edematous Pancreatitis0low10
Acute Kidney Failure0low50
Acute Kidney Injury0low50
Acute Kidney Insufficiency0low50
Acute Kidney Tubular Necrosis0low10
Acute Liver Injury, Drug-Induced0low30
Acute Lung Injury0low10
Acute Membranous Gingivitis0low10
Acute Myelogenous Leukemia0low10
Acute Myeloid Leukemia0low10
Acute Myeloid Leukemia with Maturation0low10
Acute Myeloid Leukemia without Maturation0low10
Acute Necrotizing Ulcerative Gingivitis0low10
Acute Pain0low10
Acute Pancreatitis0low10
Acute Renal Failure0low50
Acute Renal Injury0low50
Acute Renal Insufficiency0low50
Acute Respiratory Distress Syndrome0low10
Adenocarcinoma0low10
Adenocarcinoma, Basal Cell0low10
Adenocarcinoma, Granular Cell0low10
Adenocarcinoma, Oxyphilic0low10
Adenocarcinoma, Tubular0low10
Adenoma0low10
Adenoma, Basal Cell0low10
Adenoma, Follicular0low10
Adenoma, Malignant0low10
Adenoma, Microcystic0low10
Adenoma, Monomorphic0low10
Adenoma, Papillary0low10
Adenoma, Prolactin-Secreting, Pituitary0low10
Adenoma, Trabecular0low10
Adjuvant Arthritis0low10
Adrenal Gland Hyperfunction0low10
Adrenal Hyperplasia, Congenital0low40
Adrenocortical Hyperfunction0low10
Adrenocorticotropic Hormone, Inappropriate Secretion0low30
Adult Respiratory Distress Syndrome0low10
Adverse Drug Event0low40
Adverse Drug Reaction0low40
Age-Related Memory Disorders0low10
Aging0low90
AIDS0low20
AIDS Dementia Complex0low10
AIDS Encephalopathy0low10
AIDS-Related Dementia Complex0low10
Akinetic Petit Mal0low40
Alcohol Abuse0low20
Alcohol Addiction0low20
Alcohol Dependence0low20
Alcohol Drinking0low20
Alcohol Use Disorder0low20
Alcoholic Intoxication, Chronic0low20
Alcoholism0low20
Aldosteronism0medium41
Alkalosis0low20
Allergic Encephalomyelitis0low40
Allergic Encephalomyelitis, Experimental0low40
Allodynia0low110
Allodynia, Mechanical0low110
Allodynia, Tactile0low110
Allodynia, Thermal0low110
Alloxan Diabetes0low40
ALS - Amyotrophic Lateral Sclerosis0low20
Alveolitis, Fibrosing0low10
Alzheimer Dementia0low60
Alzheimer Disease0low60
Alzheimer Disease, Early Onset0low60
Alzheimer Disease, Late Onset0low60
Alzheimer Sclerosis0low60
Alzheimer Syndrome0low60
Alzheimer Type Senile Dementia0low60
Alzheimer-Type Dementia (ATD)0low60
Alzheimer's Disease0low60
Alzheimer's Disease, Focal Onset0low60
Alzheimer's Diseases0low60
Amyotrophic Lateral Sclerosis0low20
Amyotrophic Lateral Sclerosis With Dementia0low20
Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Complex 10low20
Amyotrophic Lateral Sclerosis, Guam Form0low20
Amyotrophic Lateral Sclerosis, Parkinsonism-Dementia Complex of Guam0low20
Anaplastic Astrocytoma0low10
Anasarca0medium73
Anemia0low20
Angelman Syndrome0low10
Angiitis0low20
Angiospasm, Intracranial0low30
ANLL0low10
Anochlesia0low10
Anoxemia0low20
Anoxia0low20
Anoxia-Ischemia, Brain0low20
Anoxia-Ischemia, Cerebral0low20
Anoxic-Ischemic Encephalopathy0low20
Anterior Cerebral Circulation Infarction0low10
Anterior Choroidal Artery Infarction0low10
Anterior Circulation Brain Infarction0low10
Anterior Circulation Infarction, Brain0low10
Anterior Circulation Transient Ischemic Attack0low10
Anxiety0low20
Anxiety Disorders0low10
Anxiety Neuroses0low10
Anxiety States, Neurotic0low10
Aphthae0low40
Apoplexy0low20
Apparent Mineralocorticoid Excess Syndrome0low10
Arachnidism0low10
ARDS, Human0low10
Arrhythmia0low60
Arrhythmias, Cardiac0low60
Arrythmia0low60
Arterial Hyperemia0low10
Arthritis, Adjuvant0low10
Arthritis, Adjuvant-Induced0low10
Arthritis, Collagen-Induced0low10
Arthritis, Degenerative0low20
Arthritis, Experimental0low10
Arthroses0low20
Arthrosis0low20
Ascites0low10
Asthma0low50
Asthma, Bronchial0low50
Astrocytoma0low10
Astrocytoma, Grade I0low10
Astrocytoma, Grade II0low10
Astrocytoma, Grade III0low10
Astrocytoma, Grade IV0low20
Astrocytoma, Protoplasmic0low10
Astrocytoma, Subependymal Giant Cell0low10
Astrocytosis0low10
Astroglioma0low10
Astrogliosis0low10
Ataxia0low10
Ataxia, Appendicular0low10
Ataxia, Limb0low10
Ataxia, Motor0low10
Ataxia, Sensory0low10
Ataxia, Truncal0low10
Ataxy0low10
Atherogenesis0low10
Atherosclerosis0low10
Atonic Absence Seizure0low130
Atonic Absence Seizures0low130
Atonic Seizure0low130
Atonic Seizures0low130
Atrial Fibrillation0low30
Atrioventricular Dissociation0low10
Atrioventricular Nodal Re-Entrant Tachycardia0low10
Atrioventricular Reentrant Tachycardia0low10
Atypical Lipoma0low10
Audiogenic Epilepsy0low10
Aura0low230
Auricular Fibrillation0low30
Auriculo-Ventricular Dissociation0low10
Autoimmune Diabetes0low10
Autoimmune Encephalomyelitis, Experimental0low40
Autoimmune Experimental Encephalomyelitis0low40
Autosomal Dominant Juvenile Parkinson Disease0low20
Autosomal Dominant Juvenile Parkinsonism0low20
Autosomal Dominant Parkinsonism0low20
Autosomal Recessive Juvenile Parkinson Disease0low20
Autosomal Recessive Juvenile Parkinsonism0low20
Autosomal Recessive Parkinsonism0low20
Awakening Epilepsy0low230
B Virus Infection0low10
B-Cell Chronic Lymphocytic Leukemia0low10
B-Cell Leukemia, Chronic0low10
B-Cell Malignancy, Low-Grade0low10
B-Lymphocytic Leukemia, Chronic0low10
B. burgdorferi Infection0low10
Barrett Epithelium0low10
Barrett Esophagus0low10
Barrett Metaplasia0low10
Barrett Syndrome0low10
Barrett's Esophagus0low10
Barrett's Syndrome0low10
Benign Essential Tremor0low10
Benign Frontal Childhood Epilepsy0low10
Benign Neoplasms0low20
Benign Neoplasms, Brain0low40
Benign Psychomotor Epilepsy, Childhood0low20
Binge Alcohol Consumption0low10
Binge Drinking0low10
Birth Weight0low40
Bladder Calculi0low10
Bladder Stones0low10
Bladder, Overactive0low10
Blood Clot0low10
Blood Poisoning0low20
Blood Pressure, High0medium244
Bloodstream Infection0low20
Body Weight0medium164
Body Weight, Fetal0low10
Bone Cancer0low10
Bone Loss, Osteoclastic0low10
Bone Neoplasms0low10
Bone Resorption0low10
Borrelia burgdorferi Infection0low10
Brain Anoxia-Ischemia0low20
Brain Cancer0low40
Brain Diseases0low10
Brain Disorders0low10
Brain Edema0low20
Brain Hemorrhage, Cerebral0low30
Brain Hypoxia-Ischemia0low20
Brain Infarct0low10
Brain Infarction0low10
Brain Infarction, Anterior Circulation0low10
Brain Infarction, Posterior Circulation0low10
Brain Infarction, Venous0low10
Brain Inflammation0low10
Brain Injuries0low80
Brain Injuries, Acute0low80
Brain Injuries, Focal0low80
Brain Ischemia0low100
Brain Ischemia-Anoxia0low20
Brain Ischemia-Hypoxia0low20
Brain Lacerations0low80
Brain Metastases0low40
Brain Neoplasm, Primary0low40
Brain Neoplasms0low40
Brain Neoplasms, Benign0low40
Brain Neoplasms, Malignant0low40
Brain Neoplasms, Malignant, Primary0low40
Brain Neoplasms, Primary Malignant0low40
Brain Stem Ischemia, Transient0low10
Brain Stem Transient Ischemic Attack0low10
Brain Swelling0low20
Brain TIA0low10
Brain Tumor, Primary0low40
Brain Tumor, Recurrent0low40
Brain Tumors0low40
Brainstem Ischemia, Transient0low10
Brainstem Transient Ischemic Attack0low10
Breathing Sounds0low10
Bronchial Asthma0low50
Bronchial Hyperreactivity0low10
Cadaver0low10
Calculi of Urinary Bladder0low10
Cancer0low20
Cancer of Bone0low10
Cancer of Brain0low40
Cancer of Colon0low30
Cancer of Duodenum0low10
Cancer of Liver0low10
Cancer of Lung0low10
Cancer of Pancreas0low10
Cancer of Pituitary0low20
Cancer of Prostate0low20
Cancer of Skin0low10
Cancer of Stomach0low70
Cancer of Testis0low20
Cancer of the Bone0low10
Cancer of the Brain0low40
Cancer of the Colon0low30
Cancer of the Duodenum0low10
Cancer of the Liver0low10
Cancer of the Lung0low10
Cancer of the Pancreas0low10
Cancer of the Pituitary0low20
Cancer of the Prostate0low20
Cancer of the Skin0low10
Cancer of the Stomach0low70
Cancer of the Testes0low20
Cancer of the Testis0low20
Cancer of the Thyroid0low10
Cancer of Thyroid0low10
Cancer Pain0low10
Cancer-Associated Pain0low10
Cancer-Related Pain0low10
Cancer, Embryonal0low10
Cancer, Embryonal and Mixed0low10
Cancer, Hepatocellular0low10
Candida Infection0medium21
Candidiasis0medium21
Canine Diseases0low10
Canker Sore0low40
Carcinoma0low10
Carcinoma, Anaplastic0low10
Carcinoma, Cribriform0low10
Carcinoma, Embryonal0low10
Carcinoma, Epidermoid0low10
Carcinoma, Granular Cell0low10
Carcinoma, Hepatocellular0low10
Carcinoma, Papillary, Follicular0low10
Carcinoma, Planocellular0low10
Carcinoma, Spindle-Cell0low10
Carcinoma, Squamous0low10
Carcinoma, Squamous Cell0low10
Carcinoma, Tubular0low10
Carcinoma, Undifferentiated0low10
Carcinomatosis0low10
Cardiac Arrhythmia0low60
Cardiac Arrhythmias0low60
Cardiac Dysrhythmia0low60
Cardiac Edema0low10
Cardiac Failure0medium31
Cardiac Hypertrophy0low20
Cardiomegaly0low20
Cardiometabolic Syndrome0low60
Cardiovascular Stroke0low10
Carditis0low10
Carotid Arteriopathies, Traumatic0low10
Carotid Artery Injuries0low10
Carotid Circulation Transient Ischemic Attack0low10
Carotid False Aneurysm0low10
Carotid Pseudoaneurysm0low10
Catalepsy0low10
Celiac Disease0low10
Celiac Sprue0low10
Cell Transformation, Neoplastic0low20
Central Nervous System Disorders, Intracranial0low10
Central Nervous System Intracranial Disorders0low10
Cerea Flexibilitas0low10
Cerebral Angiospasm0low30
Cerebral Anoxia-Ischemia0low20
Cerebral Artery Spasm0low30
Cerebral Astrocytoma0low10
Cerebral Edema0low20
Cerebral Edema, Cytotoxic0low20
Cerebral Edema, Vasogenic0low20
Cerebral Hemorrhage0low30
Cerebral Hypoxia-Ischemia0low20
Cerebral Infarct0low10
Cerebral Infarction0low10
Cerebral Infarction, Left Hemisphere0low10
Cerebral Infarction, Middle Cerebral Artery0low50
Cerebral Infarction, Right Hemisphere0low10
Cerebral Ischemia0low100
Cerebral Ischemia-Anoxia0low20
Cerebral Ischemia-Hypoxia0low20
Cerebral Ischemia, Transient0low10
Cerebral Parenchymal Hemorrhage0low30
Cerebral Stroke0low20
Cerebral Vasospasm0low30
Cerebral, Left Hemisphere, Infarction0low10
Cerebral, Right Hemisphere, Infarction0low10
Cerebrovascular Accident0low20
Cerebrovascular Accident, Acute0low20
Cerebrovascular Apoplexy0low20
Cerebrovascular Spasm0low30
Cerebrovascular Stroke0low20
Charcot Disease0low20
Chemical and Drug Induced Liver Injury0low30
Chemical Dependence0medium11
Chemically-Induced Liver Toxicity0low30
Childhood Absence Epilepsy0low40
Childhood Benign Frontal Epilepsy0low10
Childhood Benign Psychomotor Epilepsy0low20
Childhood Cerebral Astrocytoma0low10
Cholecystoduodenal Fistula0low10
Cholera Infantum0low10
Chromosome 6-Linked Autosomal Recessive Parkinsonism0low20
Chronic Disease0medium164
Chronic Hepatitis0low10
Chronic Illness0medium164
Chronic Kidney Diseases0low10
Chronic Kidney Insufficiency0low10
Chronic Lymphocytic Leukemia0low10
Chronic Pain0low20
Chronic Pancreatitis0low10
Chronic Renal Diseases0low10
Chronic Renal Insufficiency0low10
Chronically Ill0medium164
Cirrhosis0low40
Cirrhosis, Liver0low10
Clonic Seizure0low130
Clonic Seizures0low130
CNS Disorders, Intracranial0low10
Cochlear Hearing Loss0low20
Cognition Disorders0low10
Cognitive Decline0low10
Cognitive Dysfunction0low10
Cognitive Impairments0low10
Cold Sore0low10
Colitis0low30
Colitis Gravis0low10
Colitis, Ulcerative0low10
Collagen Arthritis0low10
Colon Cancer0low30
Colon Neoplasms0low30
Colonic Cancer0low30
Colonic Diseases0low10
Colonic Diseases, Functional0low10
Colonic Neoplasms0low30
Colovesical Fistula0low10
Compensatory Hyperinsulinemia0low20
Complex Partial Seizure0low130
Complex Partial Seizures0low130
Complex Partial Status Epilepticus0low10
Complications of Diabetes Mellitus0low10
Complications, Hematologic Pregnancy0low10
Congenital Adrenal Hyperplasia0low40
Congenital Zika Syndrome0low10
Congenital Zika Virus Infection0low10
Congestive Heart Failure0medium31
Conn Syndrome0medium41
Conn's Syndrome0medium41
Constriction, Pathologic0low10
Constriction, Pathological0low10
Contracture, Volkmann0low10
Conus Medullaris Syndrome0low10
Convulsion0low130
Convulsion, Non-Epileptic0low130
Convulsions0low130
Convulsive Seizure0low130
Convulsive Seizures0low130
Coordination Impairment0low10
Coronary Disease0low10
Coronary Heart Disease0low10
Corpse0low10
Corticotroph Adenoma0low10
Crackles0low10
Craniofacial Pain0low10
Crescendo Transient Ischemic Attacks0low10
Cryptogenic Chronic Hepatitis0low10
Curling Ulcer0medium6324
Curling's Ulcer0medium6324
Cursive Epilepsy0low10
Cushing Disease0low30
Cushing Disease, Pituitary0low30
Cushing Syndrome0low10
Cushing's Disease0low30
Cushing's Syndrome0low10
CVA (Cerebrovascular Accident)0low20
Cystitis0low10
Cystoliths0low10
Cytotoxic Brain Edema0low20
Cytotoxic Cerebral Edema0low20
Deaf Mutism0low10
Deaf-Mutism0low10
Deafness0low10
Deafness Neurosensory0low20
Deafness Permanent0low10
Deafness, Acquired0low10
Decision Making Reflex Epilepsy0low10
Deficiency, Magnesium0low10
Deficiency, Oxygen0low20
Deglutition Disorders0low10
Delayed Effects, Prenatal Exposure0low90
Delayed Puberty0low10
Dementia Complex, Acquired Immune Deficiency Syndrome0low10
Dementia Complex, AIDS-Related0low10
Dementia With Amyotrophic Lateral Sclerosis0low20
Dementia, Alzheimer Type0low60
Dementia, Presenile0low60
Dementia, Primary Senile Degenerative0low60
Dementia, Senile0low60
Depression0low30
Depression, Endogenous0low10
Depression, Neurotic0low10
Depression, Unipolar0low10
Depressive Disorder0low10
Depressive Syndrome0low10
Dermatitis Medicamentosa0low10
Dermatitis, Adverse Drug Reaction0low10
Dermatoses0low10
Dermatosis0low10
Diabetes Complications0low10
Diabetes Mellitus0low10
Diabetes Mellitus, Adult-Onset0medium51
Diabetes Mellitus, Brittle0low10
Diabetes Mellitus, Experimental0low40
Diabetes Mellitus, Insulin-Dependent0low10
Diabetes Mellitus, Insulin-Dependent, 10low10
Diabetes Mellitus, Juvenile-Onset0low10
Diabetes Mellitus, Ketosis-Prone0low10
Diabetes Mellitus, Ketosis-Resistant0medium51
Diabetes Mellitus, Maturity-Onset0medium51
Diabetes Mellitus, Non Insulin Dependent0medium51
Diabetes Mellitus, Non-Insulin-Dependent0medium51
Diabetes Mellitus, Noninsulin Dependent0medium51
Diabetes Mellitus, Noninsulin-Dependent0medium51
Diabetes Mellitus, Slow-Onset0medium51
Diabetes Mellitus, Stable0medium51
Diabetes Mellitus, Sudden-Onset0low10
Diabetes Mellitus, Type 10low10
Diabetes Mellitus, Type 20medium51
Diabetes Mellitus, Type I0low10
Diabetes Mellitus, Type II0medium51
Diabetes-Related Complications0low10
Diabetes, Autoimmune0low10
Diabetic Angiopathies0low10
Diabetic Cardiomyopathies0low10
Diabetic Complications0low10
Diabetic Vascular Complications0low10
Diabetic Vascular Diseases0low10
Diarrhea0low10
Diathesis0low40
Diffuse Well-Differentiated Lymphocytic Lymphoma0low10
Disease Exacerbation0low30
Disease Models, Animal0low680
Disease Progression0low30
Disease Susceptibility0low40
Disease, Pulmonary0low10
Diseases of Pharynx0low10
Diseases, Metabolic0low10
Diseases, Pulmonary0low10
Disrupted In B-Cell Malignancy0low10
Dog Diseases0low10
Dropsy0medium73
Drug Abuse0medium11
Drug Addiction0medium11
Drug Dependence0medium11
Drug Eruptions0low10
Drug Habituation0medium11
Drug Side Effects0low40
Drug Toxicity0low40
Drug Use Disorders0medium11
Drug Withdrawal Symptoms0medium11
Drug-Induced Acute Liver Injury0low30
Drug-Induced Liver Disease0low30
Drug-Induced Liver Injury0low30
Drug-Related Side Effects and Adverse Reactions0low40
Dry Eye0low10
Dry Eye Disease0low10
Dry Eye Syndromes0low10
Dumping Syndrome0low10
Duodenal Cancer0low10
Duodenal Diseases0low20
Duodenal Neoplasms0low10
Duodenal Reflux0low10
Duodenal Ulcer0medium6324
Duodenitis0medium22
Duodeno-Gastric Reflux0low10
Duodenogastric Reflux0low10
Dyscoordination0low10
Dyskinesia, Drug-Induced0low10
Dyskinesia, Medication-Induced0low10
Dysmetabolic Syndrome X0low60
Dyspepsia0low20
Dysphagia0low10
Dyssynergia0low10
E coli Infections0low10
E. coli Infection0low10
Early Onset Alzheimer Disease0low60
Early Pregnancy Loss0low10
Eating-Induced Epilepsy0low10
Ectopic ACTH Syndrome0low10
Edema0medium73
Edema, Cardiac0low10
Edema, Pulmonary0low10
Edemas, Pulmonary0low10
Electrolytes0medium61
Embolic Infarction, Middle Cerebral Artery0low50
Embolus, Middle Cerebral Artery0low50
Embryonal Neoplasms0low10
Encephalitis0low10
Encephalitis, Polio0low10
Encephalitis, Rasmussen0low10
Encephalomyelitis, Allergic0low40
Encephalomyelitis, Autoimmune, Experimental0low40
Encephalomyelitis, Experimental Autoimmune0low40
Encephalon Diseases0low10
Encephalopathy0low10
Encephalopathy, AIDS0low10
Encephalopathy, Anoxic-Ischemic0low20
Encephalopathy, HIV0low10
Encephalopathy, Hypoxic-Ischemic0low20
Encephalopathy, Ischemic0low100
Endogenous Hyperinsulinism0low20
Enlarged Heart0low20
Enterocutaneous Fistula0low10
Entrapment Neuropathies0low10
Epidemic Acute Poliomyelitis0low10
Epilepsy0low230
Epilepsy Juvenile Absence0low40
Epilepsy, Absence0low40
Epilepsy, Absence, Atypical0low40
Epilepsy, Anterior Fronto-Polar0low10
Epilepsy, Benign Frontal, Childhood0low10
Epilepsy, Benign Psychomotor, Childhood0low20
Epilepsy, Cingulate0low10
Epilepsy, Cryptogenic0low230
Epilepsy, Frontal Lobe0low10
Epilepsy, Lateral Temporal0low20
Epilepsy, Minor0low40
Epilepsy, Opercular0low10
Epilepsy, Orbito-Frontal0low10
Epilepsy, Petit Mal0low40
Epilepsy, Photogenic0low10
Epilepsy, Reading0low10
Epilepsy, Reflex0low10
Epilepsy, Supplementary Motor0low10
Epilepsy, Temporal Lobe0low20
Epilepsy, Uncinate0low20
Epileptic Seizure0low130
Epileptic Seizures0low130
Epileptiform Neuralgia0low20
Epithelial Neoplasms, Malignant0low10
Epithelial Tumors, Malignant0low10
Epithelioma0low10
Erosive Duodenitis0medium22
Erythema Multiforme0low10
Escherichia coli Infections0low10
Esophageal Diseases0medium22
Esophageal Dysphagia0low10
Esophageal Reflux0medium41
Esophagitis0medium21
Esophagitis, Peptic0medium114
Esophagitis, Reflux0medium114
Esophagus, Barrett0low10
Essential Tremor0low10
Ethanol Abuse0low20
Evaporative Dry Eye0low10
Evaporative Dry Eye Disease0low10
Evaporative Dry Eye Syndrome0low10
Exanthem0low10
Exanthema0low10
Exogenous Hyperinsulinism0low20
Experimental Allergic Encephalomyelitis0low40
Experimental Autoimmune Encephalomyelitis0low40
Experimental Diabetes Mellitus0low40
Experimental Lung Inflammation0low20
Experimental Mammary Neoplasms0low10
Experimental Parkinson Disease0low20
Experimental Parkinsonism0low20
Experimental Parkinsonism, MPTP-Induced0low20
External Nerve Compression Syndromes0low10
Extramedullary Spinal Cord Compression0low10
Extravasation of Contrast Media0low10
Extravasation of Diagnostic and Therapeutic Materials0low10
Extravasation of Diagnostic, Therapeutic Materials0low10
Extravascular Hemolysis0low30
Eye Injuries0low10
Face Pain0low10
Facial Pain0low10
False Aneurysm, Carotid0low10
Familial Alzheimer Disease (FAD)0low60
Familial Atrial Fibrillation0low30
Familial Hyperpotassemia and Hypertension0medium41
Familial Hypertensive Hyperkalemia0medium41
Familial Juvenile Parkinsonism0low20
Familial Parkinson Disease, Autosomal Recessive0low20
Familial Tremor0low10
Fatty Liver0low20
Fatty Liver, Nonalcoholic0low10
Fatty Tumor0low10
Fetal Growth Restriction0low40
Fetal Growth Retardation0low40
Fetal Malnutrition0low10
Fetal Nutrition Disorders0low10
Fetal Weight0low10
Fever Blister0low10
Fever, Zika0low10
Fibrillary Astrocytoma0low10
Fibroses, Pulmonary0low10
Fibrosis0low40
Fibrosis, Liver0low10
Fibrosis, Pulmonary0low10
Flexibility, Waxy0low10
Focal Brain Injuries0low80
Focal Onset Alzheimer's Disease0low60
Fothergill Disease0low20
Froehlich's Syndrome0low10
Frontal Epilepsy, Benign, Childhood0low10
Frontal Lobe Epilepsy0low10
Functional Colonic Diseases0low10
Functional Gastrointestinal Disorders0low10
Fusospirillary Gingivitis0low10
Fusospirillosis0low10
Gastric Acid Reflux0medium41
Gastric Acid Reflux Disease0medium41
Gastric Cancer0low70
Gastric Cancer, Familial Diffuse0low70
Gastric Diseases0low20
Gastric Fistula0low10
Gastric Neoplasms0low70
Gastric Ulcer0medium12031
Gastritis0medium103
Gastritis, Atrophic0medium21
Gastro-Esophageal Reflux0medium41
Gastro-Esophageal Reflux Disease0medium41
Gastro-oesophageal Reflux0medium41
Gastroduodenal Ulcer0medium7812
Gastroenteritis0low10
Gastroesophageal Reflux0medium41
Gastroesophageal Reflux Disease0medium41
Gastrointestinal Diseases0low10
Gastrointestinal Disorders0low10
Gastrointestinal Disorders, Functional0low10
Gastrointestinal Hemorrhage0medium41
Gehrig's Disease0low20
Gemistocytic Astrocytoma0low10
Generalized Absence Seizure0low130
Generalized Absence Seizures0low130
Generalized Convulsive Status Epilepticus0low10
Generalized Tonic-Clonic Seizures0low130
Genetic Skin Diseases0low10
Genital Herpes0medium11
GERD0medium41
Germ Cell and Embryonal Neoplasms0low10
Germ Cell and Embryonic Neoplasms0low10
Germ Cell Cancer0low10
Germ Cell Neoplasms0low10
Germ Cell Tumor0low10
Giant Cell Glioblastoma0low20
Gingivitis, Necrotizing Ulcerative0low10
Gingivostomatitis, Herpetic0low20
Glaucoma0low10
Glaucoma, Suspect0medium11
Glial Cell Tumors0low40
Glial Scar0low10
Glioblastoma0low20
Glioblastoma Multiforme0low20
Glioblastoma with Sarcomatous Component0low10
Glioma0low40
Glioma, Astrocytic0low10
Gliosarcoma0low10
Gliosis0low10
Glucose Intolerance0low20
Gluten Enteropathy0low10
Gluten-Sensitive Enteropathy0low10
Gordon Hyperkalemia-Hypertension Syndrome0medium41
Grand Mal Status Epilepticus0low10
Great Pox0low10
Growth Retardation, Intrauterine0low40
Guam Disease0low20
Guam Form of Amyotrophic Lateral Sclerosis0low20
Haemolysis0low30
Hamartoma0low10
Happy Puppet Syndrome0low10
Hearing Loss Permanent0low10
Hearing Loss, Cochlear0low20
Hearing Loss, Complete0low10
Hearing Loss, Extreme0low10
Hearing Loss, Sensorineural0low20
Heart Attack0low10
Heart Block0low10
Heart Decompensation0medium31
Heart Disease, Ischemic0low50
Heart Enlargement0low20
Heart Failure0medium31
Heart Failure, Congestive0medium31
Heart Failure, Left-Sided0medium31
Heart Failure, Right-Sided0medium31
Heart Hypertrophy0low20
Hematochezia0medium41
Hematologic Pregnancy Complications0low10
Hemolysis0low30
Hemorrhage, Cerebral0low30
Hemorrhage, Cerebrum0low30
Hemorrhage, Gastrointestinal0medium41
Hemorrhage, Peptic Ulcer0low40
Hemorrhage, Subarachnoid0low30
Hepatic Cancer0low10
Hepatic Cirrhosis0low10
Hepatic Neoplasms0low10
Hepatitis0low10
Hepatitis, Chronic0low10
Hepatitis, Chronic Active0low10
Hepatitis, Chronic Persistent0low10
Hepatitis, Chronic, Cryptogenic0low10
Hepatitis, Drug-Induced0low30
Hepatitis, Toxic0low30
Hepatocellular Cancer0low10
Hepatocellular Carcinoma0low10
Hepatoma0low10
Hereditary Essential Tremor0low10
Herpes Genitalis0medium11
Herpes Labialis0low10
Herpes Simplex Virus Genital Infection0medium11
Herpes Simplex, Genital0medium11
Herpes Simplex, Labial0low10
Herpes Simplex, Oral0low20
Herpesviridae Infections0low10
Herpesvirus Infections0low10
Hibernoma0low10
HIV Dementia0low10
HIV Encephalopathy0low10
HIV-1 Cognitive and Motor Complex0low10
HIV-1-Associated Cognitive Motor Complex0low10
HIV-Associated Cognitive Motor Complex0low10
Hydrops0medium73
Hyperadrenalism0low10
Hyperadrenocorticism0low10
Hyperaldosteronism0medium41
Hyperalgesia0low110
Hyperalgesia, Mechanical0low110
Hyperalgesia, Primary0low110
Hyperalgesia, Secondary0low110
Hyperalgesia, Tactile0low110
Hyperalgesia, Thermal0low110
Hyperalgesic Sensations0low110
Hyperalgia0low110
Hyperalgia, Mechanical0low110
Hyperalgia, Primary0low110
Hyperalgia, Secondary0low110
Hyperandrogenism0low10
Hypercapnia0low30
Hypercorticism0low10
Hypercortisolism0low10
Hyperemia0low10
Hyperinsulinemia0low20
Hyperinsulinism0low20
Hyperkalemia0low10
Hyperlipemia0low10
Hyperlipidemia0low10
Hyperlipidemias0low10
Hyperplasia, Congenital Adrenal0low40
Hyperpotassemia0low10
Hyperpotassemia and Hypertension, Familial0medium41
Hypertension0medium244
Hypertension, Ocular0medium11
Hypertensive Hyperkalemia, Familial0medium41
Hypertriglyceridemia0low10
Hypertrophy0low10
Hypocalcemia0low10
Hypocapnia0low10
Hypochlorhydria0low10
Hypokalemia0medium195
Hypopotassemia0medium195
Hypospermatogenesis0low10
Hypothalamic Diseases0low10
Hypothalamic Dysfunction Syndromes0low10
Hypothalamic Dysinhibition Syndrome0low10
Hypothalamic Overactivity Syndrome0low10
Hypothalamic Pseudopuberty0low10
Hypothalamic-Adenohypophyseal Disorders0low10
Hypothalamic-Neurohypophyseal Disorders0low10
Hypoxemia0low20
Hypoxia0low20
Hypoxia-Ischemia, Brain0low20
Hypoxia-Ischemia, Cerebral0low20
Hypoxic-Ischemic Encephalopathy0low20
Ichthyosis0low10
IDDM0low10
Idiopathic Diffuse Interstitial Pulmonary Fibrosis0low10
Idiopathic Parkinson Disease0low10
Idiopathic Parkinson's Disease0low10
Idiopathic Proctocolitis0low10
Idiopathic Ventricular Tachycardia0low10
Immersion Related Epilepsy0low10
Immunodeficiency Syndrome, Acquired0low20
Immunologic Deficiency Syndrome, Acquired0low20
Impaired Glucose Tolerance0low20
Inadequate Sleep0low10
Inappropriate ACTH Secretion Syndrome0low30
Inappropriate Adrenocorticotropic Hormone Secretion0low30
Inborn Errors of Metabolism0low20
Incoordination0low10
Indigestion0low20
Infantile Paralysis0low10
Infarction, Anterior Cerebral Circulation0low10
Infarction, Anterior Circulation, Brain0low10
Infarction, Brain, Anterior Circulation0low10
Infarction, Brain, Posterior Circulation0low10
Infarction, Cerebral0low10
Infarction, Cerebral, Left Hemisphere0low10
Infarction, Cerebral, Right Hemisphere0low10
Infarction, Left Hemisphere, Cerebral0low10
Infarction, Middle Cerebral Artery0low50
Infarction, Posterior Circulation, Brain0low10
Infarction, Right Hemisphere, Cerebral0low10
Infections, E coli0low10
Infections, Escherichia coli0low10
Infections, Herpesviridae0low10
Infections, Herpesvirus0low10
Infections, Plasmodium0low10
Inflammation0low90
Inflammation, Brain0low10
Inflammatory Bowel Disease, Ulcerative Colitis Type0low10
Injuries, Acute Brain0low80
Injuries, Brain0low80
Injuries, Carotid Artery0low10
Injuries, Eye0low10
Injuries, Spinal Cord0low40
Injury, Ischemia-Reperfusion0low60
Injury, Myocardial Reperfusion0low30
Injury, Reperfusion0low60
Innate Inflammatory Response0low90
Insufficient Sleep0low10
Insufficient Sleep Syndrome0low10
Insulin Resistance0medium111
Insulin Resistance Syndrome X0low60
Insulin Sensitivity0medium111
Insulin-Dependent Diabetes Mellitus 10low10
Internal Nerve Compression Syndromes0low10
Intestinal Diseases0low10
Intestinal Fistula0low10
Intracerebral Hemorrhage0low30
Intracranial Angiospasm0low30
Intracranial Astrocytoma0low10
Intracranial Central Nervous System Disorders0low10
Intracranial CNS Disorders0low10
Intracranial Edema0low20
Intracranial Neoplasms0low40
Intracranial Vascular Spasm0low30
Intracranial Vasospasm0low30
Intraocular Pressure0medium41
Intrauterine Growth Restriction0low40
Intrauterine Growth Retardation0low40
Intravascular Hemolysis0low30
Invasiveness, Neoplasm0low30
Ischemia0low20
Ischemia-Anoxia, Brain0low20
Ischemia-Anoxia, Cerebral0low20
Ischemia-Hypoxia, Brain0low20
Ischemia-Hypoxia, Cerebral0low20
Ischemia-Reperfusion Injury0low60
Ischemia, Cerebral0low100
Ischemia, Myocardial0low50
Ischemic Attack, Transient0low10
Ischemic Contracture0low10
Ischemic Encephalopathy0low100
Ischemic Heart Disease0low50
Ischemic-Hypoxic Encephalopathy0low20
Jacksonian Seizure0low130
Juvenile Absence Epilepsy0low40
Juvenile Parkinson Disease0low20
Juvenile Parkinson Disease, Autosomal Dominant0low20
Juvenile Parkinson Disease, Autosomal Recessive0low20
Juvenile Parkinsonism, Autosomal Dominant0low20
Juvenile Parkinsonism, Autosomal Recessive0low20
Juvenile Pilocytic Astrocytoma0low10
Juvenile-Onset Diabetes0low10
Keratitis0low10
Kidney Diseases0medium11
Kidney Failure, Acute0low50
Kidney Insufficiency, Acute0low50
Kidney Insufficiency, Chronic0low10
Kidney Tubular Necrosis, Acute0low10
Lack of Coordination0low10
Lactotroph Adenoma0low10
Laryngeal Spasm0low10
Laryngismus0low10
Laryngospasm0low10
Late Effects, Prenatal Exposure0low90
Late Onset Alzheimer Disease0low60
Leanness0low10
Left Hemisphere, Cerebral Infarction0low10
Left Hemisphere, Infarction, Cerebral0low10
Left Middle Cerebral Artery Infarction0low50
Left-Sided Heart Failure0medium31
Lesion of Sciatic Nerve0low10
Leukemia, Acute Myelogenous0low10
Leukemia, Acute Myeloid0low10
Leukemia, B Cell, Chronic0low10
Leukemia, B-Cell, Chronic0low10
Leukemia, Chronic Lymphatic0low10
Leukemia, Chronic Lymphocytic0low10
Leukemia, Chronic Lymphocytic, B-Cell0low10
Leukemia, Lymphoblastic, Chronic0low10
Leukemia, Lymphocytic, Chronic0low10
Leukemia, Lymphocytic, Chronic, B Cell0low10
Leukemia, Lymphocytic, Chronic, B-Cell0low10
Leukemia, Myeloblastic, Acute0low10
Leukemia, Myelocytic, Acute0low10
Leukemia, Myelogenous, Acute0low10
Leukemia, Myeloid, Acute0low10
Leukemia, Myeloid, Acute, M10low10
Leukemia, Myeloid, Acute, M20low10
Leukemia, Nonlymphoblastic, Acute0low10
Leukemia, Nonlymphocytic, Acute0low10
Lewy Body Parkinson Disease0low10
Lewy Body Parkinson's Disease0low10
Libman-Sacks Disease0low10
Lip Diseases0low10
Lipemia0low10
Lipidemia0low10
Lipoma0low10
Lipoma, Pleomorphic0low10
Lipomata0low10
Lipomatosis, Multiple0low10
Liver Cancer0low10
Liver Cancer, Adult0low10
Liver Cell Carcinoma0low10
Liver Cell Carcinoma, Adult0low10
Liver Cirrhosis0low10
Liver Fibrosis0low10
Liver Injury, Drug-Induced0low30
Liver Injury, Drug-Induced, Acute0low30
Liver Neoplasms0low10
Liver Steatosis0low20
Lobar Pneumonia0low20
Lou Gehrig Disease0low20
Lou Gehrig's Disease0low20
Lou-Gehrigs Disease0low20
Low Sperm Count0low10
Lower Nephron Nephrosis0low10
Lung Cancer0low10
Lung Diseases0low10
Lung Inflammation0low20
Lung Injury, Acute0low10
Lung Neoplasms0low10
Lung Sounds0low10
Lupus Erythematosus Disseminatus0low10
Lupus Erythematosus, Systemic0low10
Lyme Arthritis0low10
Lyme Borreliosis0low10
Lyme Disease0low10
Lymphoblastic Leukemia, Chronic0low10
Lymphocytic Leukemia, Chronic0low10
Lymphocytic Leukemia, Chronic, B Cell0low10
Lymphocytic Leukemia, Chronic, B-Cell0low10
Lymphocytic Lymphoma0low10
Lymphocytic Lymphoma, Diffuse, Well Differentiated0low10
Lymphocytic Lymphoma, Diffuse, Well-Differentiated0low10
Lymphocytic Lymphoma, Well Differentiated0low10
Lymphocytic Lymphoma, Well-Differentiated0low10
Lymphoma, Lymphocytic0low10
Lymphoma, Lymphocytic, Diffuse, Well Differentiated0low10
Lymphoma, Lymphocytic, Diffuse, Well-Differentiated0low10
Lymphoma, Lymphocytic, Well Differentiated0low10
Lymphoma, Lymphocytic, Well-Differentiated0low10
Lymphoma, Lymphoplasmacytoid, CLL0low10
Lymphoma, Small Lymphocytic0low10
Lymphoma, Small Lymphocytic, Plasmacytoid0low10
Lymphoma, Small-Cell0low10
Lymphoplasmacytoid Lymphoma, CLL0low10
Macroprolactinoma0low10
Maculopapular Drug Eruption0low10
Maculopapular Exanthem0low10
Magnesium Deficiency0low10
Malaria0low10
Malaria, Falciparum0low10
Malignancy0low20
Malignant Epithelial Neoplasms0low10
Malignant Glioma0low40
Malignant Neoplasms0low20
Malignant Neoplasms, Brain0low40
Malignant Primary Brain Neoplasms0low40
Malignant Primary Brain Tumors0low40
Malnourishment0low10
Malnutrition0low10
Malnutrition, Fetal0low10
Mammary Neoplasms, Experimental0low10
Marginal Ulcer0medium7812
Marsh Fever0low10
Maturity-Onset Diabetes0medium51
Maturity-Onset Diabetes Mellitus0medium51
MCA Infarct0low50
MCA Infarction0low50
Mechanical Allodynia0low110
Mechanical Hyperalgesia0low110
Medication-Induced Dyskinesia0low10
Melancholia0low10
Memory Deficits0low10
Memory Disorder, Semantic0low10
Memory Disorder, Spatial0low10
Memory Disorders0low10
Memory Disorders, Age-Related0low10
Memory Loss0low10
Mental Deterioration0low10
Metabolic Cardiovascular Syndrome0low60
Metabolic Diseases0low10
Metabolic Syndrome0low60
Metabolic Syndrome X0low60
Metabolic X Syndrome0low60
Metabolism Errors, Inborn0low20
Metabolism, Inborn Errors0low20
Microangiopathy, Diabetic0low10
Microprolactinoma0low10
Middle Cerebral Artery Circulation Infarction0low50
Middle Cerebral Artery Embolic Infarction0low50
Middle Cerebral Artery Embolus0low50
Middle Cerebral Artery Infarction0low50
Middle Cerebral Artery Occlusion0low50
Middle Cerebral Artery Stroke0low50
Middle Cerebral Artery Syndrome0low50
Middle Cerebral Artery Thrombosis0low50
Middle Cerebral Artery Thrombotic Infarction0low50
Mild Cognitive Impairment0low10
Mild Neurocognitive Disorder0low10
Mineralocorticoid Excess Syndrome, Apparent0low10
Miscarriage0low10
Mixed Glioma0low40
MODY0medium51
Moniliasis0medium21
Morbilliform Drug Reaction0low10
Morbilliform Exanthem0low10
Morphine Abuse0medium11
Morphine Addiction0medium11
Morphine Dependence0medium11
Motor Neuron Disease, Amyotrophic Lateral Sclerosis0low20
Mouth Diseases0low10
MPTP-Induced Experimental Parkinsonism0low20
MS (Multiple Sclerosis)0low10
Multiple Sclerosis0low10
Multiple Sclerosis, Acute Fulminating0low10
Muscle Contraction0low180
Muscle Relaxation0low20
Muscle Tissue Neoplasms0low10
Musicogenic Epilepsy0low10
Myeloblastic Leukemia, Acute0low10
Myelocytic Leukemia, Acute0low10
Myelogenous Leukemia, Acute0low10
Myeloid Leukemia, Acute0low10
Myeloid Leukemia, Acute, M10low10
Myeloid Leukemia, Acute, M20low10
Myelopathy, Compressive0low10
Myelopathy, Traumatic0low40
Myoblastoma0low10
Myocardial Failure0medium31
Myocardial Infarct0low10
Myocardial Infarction0low10
Myocardial Ischemia0low50
Myocardial Ischemic Reperfusion Injury0low30
Myocardial Reperfusion Injury0low30
Myocarditis0low10
Myoclonic Seizure0low130
Myoclonic Seizures0low130
Myofacial Pain0low10
Myofibroblastoma0low10
Myoglobinuria0low20
NAFLD0low10
Nasal Catarrh0low20
Necrosis0low50
Necrotic Arachnidism0low10
Neoplasia0low20
Neoplasm0low20
Neoplasm Invasion0low30
Neoplasm Invasiveness0low30
Neoplasm-Associated Pain0low10
Neoplasm-Related Pain0low10
Neoplasms0low20
Neoplasms, Benign0low20
Neoplasms, Bone0low10
Neoplasms, Brain0low40
Neoplasms, Brain, Benign0low40
Neoplasms, Brain, Malignant0low40
Neoplasms, Brain, Primary0low40
Neoplasms, Colonic0low30
Neoplasms, Embryonal0low10
Neoplasms, Embryonal and Mixed0low10
Neoplasms, Experimental Mammary0low10
Neoplasms, Gastric0low70
Neoplasms, Germ Cell0low10
Neoplasms, Germ Cell and Embryonal0low10
Neoplasms, Germ Cell and Embryonic0low10
Neoplasms, Hepatic0low10
Neoplasms, Intracranial0low40
Neoplasms, Liver0low10
Neoplasms, Lung0low10
Neoplasms, Malignant Epithelial0low10
Neoplasms, Muscle Tissue0low10
Neoplasms, Pancreatic0low10
Neoplasms, Prostate0low20
Neoplasms, Prostatic0low20
Neoplasms, Pulmonary0low10
Neoplasms, Skin0low10
Neoplasms, Stomach0low70
Neoplasms, Testicular0low20
Neoplasms, Testis0low20
Neoplasms, Thyroid0low10
Neoplastic Cell Transformation0low20
Neoplastic Transformation, Cell0low20
Nerve Compression Syndromes0low10
Nerve Compression Syndromes, External0low10
Nerve Compression Syndromes, Internal0low10
Nerve Degeneration0low40
Nerve Entrapments0low10
Nerve Pain0low130
Neuralgia0low130
Neuralgia-Neuritis, Sciatic Nerve0low10
Neuralgia, Atypical0low130
Neuralgia, Iliohypogastric Nerve0low130
Neuralgia, Ilioinguinal0low130
Neuralgia, Perineal0low130
Neuralgia, Stump0low130
Neuralgia, Supraorbital0low130
Neuralgia, Vidian0low130
Neuralgic Facial Pain0low10
Neuroblastoma0low60
Neurodynia0low130
Neurogenic Inflammation0low10
Neuron Degeneration0low40
Neuropathic Pain0low130
Neuroses, Anxiety0low10
Neurosis, Depressive0low10
NIDDM0medium51
Nocturia0low10
Non-alcoholic Fatty Liver Disease0low10
Non-Convulsive Status Epilepticus0low10
Non-Epileptic Seizure0low130
Non-Epileptic Seizures0low130
Nonalcoholic Fatty Liver Disease0low10
Nonalcoholic Steatohepatitis0low10
Nonepileptic Seizure0low130
Nonepileptic Seizures0low130
Noninsulin-Dependent Diabetes Mellitus0medium51
Nonlymphoblastic Leukemia, Acute0low10
Nonlymphocytic Leukemia, Acute0low10
Nonsustained Ventricular Tachycardia0low10
Nutrition Disorders, Fetal0low10
Nutritional Deficiency0low10
Nycturia0low10
Obesity0medium161
Occlusion, Middle Cerebral Artery0low50
Ocular Hypertension0medium11
Oligoasthenoteratozoospermia0low10
Oligoastrocytoma, Mixed0low10
Oligospermia0low10
Oligozoospermia0low10
Oncological Pain0low10
Oncology Pain0low10
Organic Mental Disorders, Substance-Induced0medium11
Orofacial Pain0low10
Oropharyngeal Dysphagia0low10
Osteoarthritis0low20
Osteoarthrosis0low20
Osteoarthrosis Deformans0low20
Osteoclastic Bone Loss0low10
Overactive Bladder0low10
Overactive Detrusor0low10
Overactive Detrusor Function0low10
Overactive Urinary Bladder0low10
Overinclusion0low10
Oxygen Deficiency0low20
Pain0medium112
Pain, Burning0medium112
Pain, Chronic0low20
Pain, Crushing0medium112
Pain, Facial0low10
Pain, Migratory0medium112
Pain, Radiating0medium112
Pain, Splitting0medium112
Palmoplantaris Pustulosis0low10
Palsy0low10
Paludism0low10
Pancreas Cancer0low10
Pancreas Neoplasms0low10
Pancreatic Cancer0low10
Pancreatic Neoplasms0low10
Pancreatic Parenchyma with Edema0low10
Pancreatic Parenchymal Edema0low10
Pancreatitis0low10
Pancreatitis, Acute0low10
Pancreatitis, Acute Edematous0low10
Pancreatitis, Chronic0low10
Paralysis0low10
Paralysis Agitans0low10
Parkinson Disease0low10
Parkinson Disease 20low20
Parkinson Disease 2, Autosomal Recessive Juvenile0low20
Parkinson Disease Autosomal Recessive, Early Onset0low20
Parkinson Disease, Autosomal Dominant. Juvenile0low20
Parkinson Disease, Experimental0low20
Parkinson Disease, Familial, Autosomal Recessive0low20
Parkinson Disease, Idiopathic0low10
Parkinson Disease, Juvenile0low20
Parkinson Disease, Juvenile, Autosomal Dominant0low20
Parkinson Disease, Juvenile, Autosomal Recessive0low20
Parkinson's Disease0low10
Parkinson's Disease, Idiopathic0low10
Parkinson's Disease, Lewy Body0low10
Parkinsonian Diseases0low20
Parkinsonian Disorders0low20
Parkinsonian Syndrome0low20
Parkinsonian Syndromes0low20
Parkinsonism0low20
Parkinsonism, Early Onset, with Diurnal Fluctuation0low20
Parkinsonism, Early-Onset, With Diurnal Fluctuation0low20
Parkinsonism, Experimental0low20
Parkinsonism, Juvenile0low20
Parkinsonism, Juvenile, Autosomal Dominant0low20
Parkinsonism, Juvenile, Autosomal Recessive0low20
Paroxysmal Atrial Fibrillation0low30
Paroxysmal Nerve Pain0low130
Paroxysmal Supraventricular Tachycardia0low10
Partial Seizure0low130
Partial Seizures0low130
Passive Hyperemia0low10
Pathologic Constriction0low10
Pediatric Respiratory Distress Syndrome0low10
Peptic Ulcer0medium7812
Peptic Ulcer Hemorrhage0low40
Peptic Ulcer Perforation0low20
Periadenitis Mucosa Necrotica Recurrens0low40
Perinatal Subarachnoid Hemorrhage0low30
Peripancreatic Fat Necrosis0low10
Peripheral Nerve Diseases0low10
Peripheral Nerve Injuries0low20
Peripheral Nerve Injury0low20
Peripheral Nervous System Disease0low10
Peripheral Nervous System Diseases0low10
Peripheral Nervous System Disorders0low10
Peripheral Neuropathies0low10
Persistent Atrial Fibrillation0low30
Petit Mal Convulsion0low130
Petit Mal Epilepsy0low40
Petit Mal Status0low10
Phagedenic Gingivitis0low10
Pharyngeal Diseases0low10
Pharynx Diseases0low10
Photosensitive Epilepsy0low10
Pilocytic Astrocytoma0low10
Pituitary ACTH Hypersecretion0low30
Pituitary Adenoma0low20
Pituitary Adenoma, ACTH-Secreting0low10
Pituitary Adenoma, Prolactin-Secreting0low10
Pituitary Cancer0low20
Pituitary Carcinoma0low20
Pituitary Corticotropin-Secreting Adenoma0low10
Pituitary Cushing Syndrome0low30
Pituitary Diencephalic Syndrome0low10
Pituitary Neoplasms0low20
Pituitary Tumors0low20
Pituitary-Dependant Cushing Syndrome0low30
Pituitary-Dependant Hypercortisolism0low30
Pituitary-Dependant Hypercortisolism Disorder0low30
Plasmodium falciparum Malaria0low10
Plasmodium Infections0low10
Plegia0low10
Pleural Rub0low10
Pneumonia0low20
Pneumonia, Lobar0low20
Pneumonitis0low20
PNS (Peripheral Nervous System) Diseases0low10
PNS Diseases0low10
Poisoning, Blood0low20
Polio0low10
Polio Encephalitis0low10
Poliomyelitis0low10
Poliomyelitis Infection0low10
Poliomyelitis, Acute0low10
Poliomyelitis, Nonpoliovirus0low10
Poliomyelitis, Preparalytic0low10
Polyps0low10
Polyradiculitis0low10
Polyradiculopathy0low10
Polyradiculopathy, Abdominal0low10
Porphyria0low10
Porphyrias0low10
Porphyrin Disorder0low10
Post-Traumatic Myelopathy0low40
Posterior Choroidal Artery Infarction0low10
Posterior Circulation Brain Infarction0low10
Posterior Circulation Infarction, Brain0low10
Posterior Circulation Transient Ischemic Attack0low10
Postgastrectomy Syndromes0medium11
Pregnancy0low310
Pregnancy Complications, Hematologic0low10
Pregnancy Complications, Hematological0low10
Pregnancy, Hematologic Complications0low10
Prelingual Deafness0low10
Prenatal Exposure Delayed Effects0low90
Prescription Drug Abuse0medium11
Presenile Alzheimer Dementia0low60
Primary Brain Neoplasms0low40
Primary Hyperaldosteronism0medium41
Primary Malignant Brain Neoplasms0low40
Primary Malignant Brain Tumors0low40
Primary Parkinsonism0low10
Primary Senile Degenerative Dementia0low60
PRL-Secreting Pituitary Adenoma0low10
Proctitis0low10
Prolactin-Producing Pituitary Adenoma0low10
Prolactin-Secreting Pituitary Adenoma0low10
Prolactinoma0low10
Prolactinoma, Familial0low10
Prostate Cancer0low20
Prostate Neoplasms0low20
Prostatic Cancer0low20
Prostatic Neoplasms0low20
Protein Aggregation, Pathological0low10
Pseudohypoaldosteronism0medium41
Pseudohypoaldosteronism Type 10medium41
Pseudohypoaldosteronism Type 1, Autosomal Dominant0medium41
Pseudohypoaldosteronism Type 1, Autosomal Recessive0medium41
Pseudohypoaldosteronism Type 20medium41
Pseudohypoaldosteronism Type I0medium41
Pseudohypoaldosteronism Type II0medium41
Pseudohypoaldosteronism, Type I0medium41
Pseudohypoaldosteronism, Type I, Autosomal Dominant0medium41
Pseudohypoaldosteronism, Type I, Autosomal Recessive0medium41
Pseudohypoaldosteronism, Type II0medium41
Psoriasis0low10
Puberty, Delayed0low10
Pulmonary Arterial Remodeling0low10
Pulmonary Cancer0low10
Pulmonary Disease0low10
Pulmonary Diseases0low10
Pulmonary Edema0low10
Pulmonary Edemas0low10
Pulmonary Fibroses0low10
Pulmonary Fibrosis0low10
Pulmonary Inflammation0low20
Pulmonary Neoplasms0low10
Puppet Children0low10
Pustular Psoriasis of Palms and Soles0low10
Pustulosis of Palms and Soles0low10
Pustulosis Palmaris et Plantaris0low10
Pyaemia0low20
Pyemia0low20
Pykno-Epilepsy0low40
Pyknolepsy0low40
Pyohemia0low20
Pyuria0low10
Rales0low10
Ramsay Hunt Paralysis Syndrome0low20
Rash0low10
Rasmussen Encephalitis0low10
Rasmussen Syndrome0low10
Rasmussen's Syndrome0low10
Reactive Hyperemia0low10
Reading Epilepsy0low10
Reaven Syndrome X0low60
Recrudescence0medium3413
Recurrence0medium3413
Reflex Epilepsy0low10
Reflex Epilepsy, Audiogenic0low10
Reflex Epilepsy, Cursive (Running)0low10
Reflex Epilepsy, Eating-Induced0low10
Reflex Epilepsy, Musicogenic0low10
Reflex Epilepsy, Photosensitive0low10
Reflex Epilepsy, Reading0low10
Reflex Epilepsy, Visual Pattern0low10
Reflux, Gastroesophageal0medium41
Relapse0medium3413
REM Sleep Deprivation0low10
Remission, Spontaneous0medium11
Remittent Fever0low10
Renal Failure, Acute0low50
Renal Insufficiency, Acute0low50
Renal Insufficiency, Chronic0low10
Reperfusion Damage0low60
Reperfusion Injury0low60
Reperfusion Injury, Myocardial0low30
Respiratory Distress Syndrome0low10
Respiratory Distress Syndrome, Acute0low10
Respiratory Distress Syndrome, Adult0low10
Respiratory Distress Syndrome, Pediatric0low10
Respiratory Sounds0low10
Retention Disorders, Cognitive0low10
Retinal Degeneration0low10
Rhinitis0low20
Rhonchi0low10
Right Hemisphere, Cerebral Infarction0low10
Right Hemisphere, Infarction, Cerebral0low10
Right Middle Cerebral Artery Infarction0low50
Right-Sided Heart Failure0medium31
SAH (Subarachnoid Hemorrhage)0low30
Salivary Gland Diseases0medium11
Sarcomatous Glioma0low10
Sciatic Nerve Diseases0low10
Sciatic Nerve Palsy0low10
Sciatic Neuritis0low10
Sciatic Neuropathy0low10
Sclerosis, Disseminated0low10
Secondary Trigeminal Neuralgia0low20
Seizure0low130
Seizure Disorder0low230
Seizure Disorder, Absence0low40
Seizures0low130
Seizures, Auditory0low130
Seizures, Clonic0low130
Seizures, Convulsive0low130
Seizures, Epileptic0low130
Seizures, Focal0low130
Seizures, Generalized0low130
Seizures, Gustatory0low130
Seizures, Motor0low130
Seizures, Olfactory0low130
Seizures, Sensory0low130
Seizures, Somatosensory0low130
Seizures, Tonic0low130
Seizures, Tonic-Clonic0low130
Seizures, Vertiginous0low130
Seizures, Vestibular0low130
Seizures, Visual0low130
Semantic Memory Disorder0low10
Senile Dementia, Acute Confusional0low60
Senile Dementia, Alzheimer Type0low60
Sensitivity and Specificity0medium51
Sensorineural Hearing Loss0low20
Sepsis0low20
Septicemia0low20
Severe Sepsis0low20
Shock Lung0low10
Side Effects of Drugs0low40
Simple Partial Status Epilepticus0low10
Single Seizure0low130
Skin and Subcutaneous Tissue Disorders0low10
Skin Cancer0low10
Skin Diseases0low10
Skin Diseases, Genetic0low10
Skin Neoplasms0low10
Skin Rash0low10
Sleep Debt0low10
Sleep Deprivation0low10
Sleep Fragmentation0low10
Sleep Insufficiency0low10
Small-Cell Lymphoma0low10
Spatial Memory Disorder0low10
Spider Bites0low10
Spinal Cord Compression0low10
Spinal Cord Compression, Extramedullary0low10
Spinal Cord Contusion0low40
Spinal Cord Injuries0low40
Spinal Cord Laceration0low40
Spinal Cord Transection0low40
Spinal Cord Trauma0low40
Spontaneous Abortion0low10
Sprue0low10
Sprue, Celiac0low10
Sprue, Nontropical0low10
Squamous Cell Carcinoma0low10
Status Epilepticus0low10
Status Epilepticus, Complex Partial0low10
Status Epilepticus, Electrographic0low10
Status Epilepticus, Generalized0low10
Status Epilepticus, Generalized Convulsive0low10
Status Epilepticus, Grand Mal0low10
Status Epilepticus, Non-Convulsive0low10
Status Epilepticus, Simple Partial0low10
Status Epilepticus, Subclinical0low10
Steatohepatitis0low20
Steatosis of Liver0low20
Stenosis0low10
Stomach Cancer0low70
Stomach Diseases0low20
Stomach Fistula0low10
Stomach Neoplasms0low70
Stomach Ulcer0medium12031
Stomatitis, Aphthous0low40
Stomatitis, Herpetic0low20
Stomatitis, Ulcerative0low10
Streptozocin Diabetes0low40
Streptozotocin Diabetes0low40
Stricture0low10
Stridor0low10
Stroke0low20
Stroke, Acute0low20
Stroke, Middle Cerebral Artery0low50
Subarachnoid Hemorrhage0low30
Subarachnoid Hemorrhage, Aneurysmal0low30
Subarachnoid Hemorrhage, Intracranial0low30
Subarachnoid Hemorrhage, Spontaneous0low30
Subcortical Infarction0low10
Subependymal Giant Cell Astrocytoma0low10
Substance Abuse0medium11
Substance Addiction0medium11
Substance Dependence0medium11
Substance Use0medium11
Substance Use Disorders0medium11
Substance Withdrawal Syndrome0medium11
Substance-Related Disorders0medium11
Suffering, Physical0medium112
Susceptibility, Disease0low40
Swallowing Disorders0low10
Swine Diseases0low10
Symptom Cluster0low30
Syndrome0low30
Syndrome X, Insulin Resistance0low60
Syndrome X, Metabolic0low60
Syphilis0low10
Systemic Lupus Erythematosus0low10
Tachyarrhythmia0low10
Tachycardia0low10
Tachycardia, Ventricular0low10
Tactile Allodynia0low110
Tactile Reflex Epilepsy0low10
Testicular Cancer0low20
Testicular Neoplasm0low20
Testicular Neoplasms0low20
Testicular Tumor0low20
Testicular Tumors0low20
Testis Cancer0low20
Testis Neoplasms0low20
Thermal Allodynia0low110
Thesaurismosis0low10
Thinness0low10
Thrombosis0low10
Thrombosis, Middle Cerebral Artery0low50
Thrombotic Infarction, Middle Cerebral Artery0low50
Thrombus0low10
Thyroid Adenoma0low10
Thyroid Cancer0low10
Thyroid Carcinoma0low10
Thyroid Neoplasms0low10
TIA (Transient Ischemic Attack)0low10
Tic Doloureux0low20
Tic Douloureux0low20
Todd Paralysis0low10
Todd's Paralysis0low10
Tonic Clonic Seizure0low130
Tonic Seizure0low130
Tonic Seizures0low130
Tonic-Clonic Seizure0low130
Tonic-Clonic Seizures0low130
Toxic Hepatitis0low30
Toxicity, Drug0low40
Transformation, Neoplastic Cell0low20
Transient Ischemic Attack0low10
Transient Ischemic Attack, Anterior Circulation0low10
Transient Ischemic Attack, Brain Stem0low10
Transient Ischemic Attack, Brainstem0low10
Transient Ischemic Attack, Carotid Circulation0low10
Transient Ischemic Attack, Posterior Circulation0low10
Transient Ischemic Attack, Vertebrobasilar Circulation0low10
Transient Ischemic Attacks, Crescendo0low10
Trauma, Carotid Artery0low10
Tremor, Rubral0low10
Trench Mouth0low10
Trifacial Neuralgia0low20
Trigeminal Neuralgia0low20
Trigeminal Neuralgia, Idiopathic0low20
Trigeminal Neuralgia, Secondary0low20
Tumor of Rete Testis0low20
Tumor-Associated Pain0low10
Tumor-Related Pain0low10
Tumorigenic Transformation0low20
Tumors0low20
Type 1 Diabetes0low10
Type 1 Diabetes Mellitus0low10
Type 2 Diabetes0medium51
Type 2 Diabetes Mellitus0medium51
Ulcer0medium42
Ulcer, Aphthous0low40
Ulcerative Colitis0low10
Undernutrition0low10
Underweight0low10
Unipolar Depression0low10
Uremia0low10
Urinary Bladder Calculi0low10
Urinary Bladder Stones0low10
Urinary Bladder, Overactive0low10
Urinary Tract Infections0low10
Vascular Accident, Brain0low20
Vascular Remodeling0low10
Vasculitis0low20
Vasogenic Brain Edema0low20
Vasogenic Cerebral Edema0low20
Vasospasm, Intracranial0low30
Venous Congestion0low10
Venous Engorgement0low10
Venous Infarction, Brain0low10
Ventricular Fibrillation0low10
Ventricular Tachyarrhythmias0low10
Ventricular Tachycardia0low10
Vertebrobasilar Circulation Transient Ischemic Attack0low10
Vesical Calculi0low10
Vincent Angina0low10
Vincent Infection0low10
Vincent's Gingivitis0low10
Vincent's Infection0low10
Vincent's Stomatitis0low10
Visceral Steatosis0low20
Visual Pattern Reflex Epilepsy0low10
Volkmann Contracture0low10
Volkmann's Ischemic Contracture0low10
Weight Gain0low20
Wet Lung0low10
Wheezing0low10
Widespread Chronic Pain0low20
Withdrawal Symptoms0medium11
Writing-Induced Reflex Epilepsy0low10
Xeroderma0low10
Zika Fever0low10
Zika Virus Disease0low10
Zika Virus Infection0low10
ZikV Infection0low10
Zollinger-Ellison Syndrome0medium21

Research Highlights

Safety/Toxicity (8)

ArticleYear
In silico and experimental studies of bovine serum albumin-encapsulated carbenoxolone nanoparticles with reduced cytotoxicity.
Colloids and surfaces. B, Biointerfaces, Volume: 202		2021
Gap Junction Intercellular Communication Mediates Ammonia-Induced Neurotoxicity.
Neurotoxicity research, Volume: 29, Issue: 2		2016
Programming of neurotoxic cofactor CXCL-10 in HIV-1-associated dementia: abrogation of CXCL-10-induced neuro-glial toxicity in vitro by PKC activator.
Journal of neuroinflammation, Oct-18, Volume: 9		2012
Cardiac tissue slices with prolonged survival for in vitro drug safety screening.
Journal of pharmacological and toxicological methods, Volume: 66, Issue: 2		2012
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
PLoS computational biology, Volume: 7, Issue: 12		2011
Developing structure-activity relationships for the prediction of hepatotoxicity.
Chemical research in toxicology, Jul-19, Volume: 23, Issue: 7		2010
Macrophage-induced neurotoxicity is mediated by glutamate and attenuated by glutaminase inhibitors and gap junction inhibitors.
Life sciences, May-23, Volume: 82, Issue: 21-22		2008
Blocked gap junctional coupling increases glutamate-induced neurotoxicity in neuron-astrocyte co-cultures.
Journal of neuropathology and experimental neurology, Volume: 61, Issue: 2		2002
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Long-term Use (5)

ArticleYear
Susceptibility of glucocorticoids to colonic metabolism and pharmacologic intervention in the metabolism: implication for therapeutic activity of colon-specific glucocorticoid 21-sulfate sodium at the target site.
The Journal of pharmacy and pharmacology, Volume: 64, Issue: 1		2012
Sub-chronic administration of the 11beta-HSD1 inhibitor, carbenoxolone, improves glucose tolerance and insulin sensitivity in mice with diet-induced obesity.
Biological chemistry, Volume: 389, Issue: 4		2008
11 beta-hydroxysteroid dehydrogenase type 1 is a predominant 11 beta-reductase in the intact perfused rat liver.
The Journal of endocrinology, Volume: 165, Issue: 3		2000
Serum carbenoxolone in patients with gastric and duodenal ulcer: Absorption, efficacy and side-effects.
Gut, Volume: 19, Issue: 4		1978
[Peptic ulcer: new aspects of conservative therapy].
Schweizerische medizinische Wochenschrift, May-07, Volume: 107, Issue: 18		1977
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (7)

ArticleYear
Investigation of LRRC8-Mediated Volume-Regulated Anion Currents in Xenopus Oocytes.
Biophysical journal, Oct-04, Volume: 111, Issue: 7		2016
On the role of ATP release, ectoATPase activity, and extracellular ADP in the regulatory volume decrease of Huh-7 human hepatoma cells.
American journal of physiology. Cell physiology, May-15, Volume: 304, Issue: 10		2013
Interstitial volume modulates the conduction velocity-gap junction relationship.
American journal of physiology. Heart and circulatory physiology, Jan-01, Volume: 302, Issue: 1		2012
A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma.
Malaria journal, Jun-12, Volume: 7		2008
Effects of carbenoxolone on alveolar fluid clearance and lung inflammation in the rat.
Critical care medicine, Volume: 32, Issue: 9		2004
Changes in the plasma clearance and protein binding of carbenoxolone with age, and their possible relationship with adverse drug effects.
Gut, Volume: 18, Issue: 12		1977
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (7)

ArticleYear
Controlled release and enhanced biological activity of chitosan-fabricated carbenoxolone nanoparticles.
International journal of biological macromolecules, Dec-01, Volume: 164		2020
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology, Volume: 96, Issue: 5		2019
Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens.
The Journal of biological chemistry, 11-15, Volume: 294, Issue: 46		2019
Antiulcerogenic activity of chlorogenic acid in different models of gastric ulcer.
Naunyn-Schmiedeberg's archives of pharmacology, Volume: 386, Issue: 1		2013
Promotion of nasal absorption of insulin by glycyrrhetinic acid derivatives. I.
Journal of pharmacobio-dynamics, Volume: 12, Issue: 1		1989
The 11 beta-OHSD inhibitor, carbenoxolone, enhances Na retention by aldosterone and 11-deoxycorticosterone.
The American journal of physiology, Volume: 258, Issue: 3 Pt 2		1990
Gastrointestinal absorption of carbenoxolone in the rat determined in vitro and in situ: deviations from the pH-partition hypothesis.
The Journal of pharmacy and pharmacology, Volume: 28, Issue: 2		1976
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (22)

ArticleYear
Inhibition of 11β-hydroxysteroid dehydrogenase 1 by carbenoxolone affects glucose homeostasis and obesity in db/db mice.
Clinical and experimental pharmacology & physiology, Volume: 39, Issue: 1		2012
Pectin-based bioadhesive delivery of carbenoxolone sodium for aphthous ulcers in oral cavity.
AAPS PharmSciTech, Volume: 11, Issue: 2		2010
Anti-ulcerogenic effect of a whey protein isolate and collagen hydrolysates against ethanol ulcerative lesions on oral administration to rats.
Journal of medicinal food, Volume: 13, Issue: 1		2010
Protective effect of collagen derivates on the ulcerative lesions caused by oral administration of ethanol.
Journal of medicinal food, Volume: 10, Issue: 1		2007
Role of gap junction in the expression of morphine-induced antinociception.
European journal of pharmacology, Mar-27, Volume: 535, Issue: 1-3		2006
Can gap-junction blockade preferentially inhibit neuronal hypersynchrony vs. excitability?
Neuropharmacology, Volume: 41, Issue: 3		2001
Effect of carbenoxolone on the plasma renin activity and hypothalamic-pituitary-adrenal axis in congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
Clinical endocrinology, Volume: 51, Issue: 3		1999
Corticosterone induces 11 beta-HSD and mineralocorticoid specificity in an amphibian urinary bladder cell line.
The American journal of physiology, Volume: 264, Issue: 2 Pt 1		1993
Long-term therapy with carbenoxolone in the prevention of recurrence of gastric ulcer. Natural history and evolution of important side-effects and measures to avoid them.
Scandinavian journal of gastroenterology. Supplement, Volume: 65		1980
Serum carbenoxolone: ulcer-healing and metabolic effects.
Scandinavian journal of gastroenterology. Supplement, Volume: 65		1980
Effects of a gastric antisecretory-cytoprotectant 2-methyl-8-(phenylmethoxy)imidazo[1,2-a]pyridine-3-acetonitrile (Sch 28 080) on cysteamine, reserpine and stress ulcers in rats.
Arzneimittel-Forschung, Volume: 34, Issue: 7		1984
Problems associated with medical treatment of peptic ulcer disease.
The American journal of medicine, Nov-19, Volume: 77, Issue: 5B		1984
The antiviral activity against herpes simplex virus of the triterpenoid compounds carbenoxolone sodium and cicloxolone sodium.
The Journal of antimicrobial chemotherapy, Volume: 18 Suppl B		1986
The antinatriuretic and kaliuretic effects of the glucocorticoids corticosterone and cortisol following pretreatment with carbenoxolone sodium (a liquorice derivative) in the adrenalectomized rat.
Endocrinology, Volume: 124, Issue: 3		1989
Esaprazole, a new antiulcer agent, stimulates gastric mucus output in the rat.
Drugs under experimental and clinical research, Volume: 15, Issue: 9		1989
Effects of 12-sulfodehydroabietic acid monosodium salt (TA-2711), a new anti-ulcer agent, on gastric secretion and experimental ulcers in rats.
Japanese journal of pharmacology, Volume: 51, Issue: 1		1989
[Clinical treatment of inflammatory and benign ulcerous diseases of the stomach and duodenum with a new combination preparation (Aci-Tensilan) (author's transl)].
MMW, Munchener medizinische Wochenschrift, Feb-27, Volume: 118, Issue: 9		1976
Carbenoxolone: a review of its pharmacological properties and therapeutic efficacy in peptic ulcer disease.
Drugs, Volume: 11, Issue: 4		1976
Controlled trial of a carbenoxolone/alginate antacid combination in reflux oesophagitis.
Current medical research and opinion, Volume: 5, Issue: 8		1978
Double-blind study of carbenoxolone in gastric ulcer and erosions.
Annals of clinical research, Volume: 10, Issue: 1		1978
Controlled trial of a new dosage form of carbenoxolone (Pyrogastrone) in the treatment of reflux esophagitis.
The American journal of digestive diseases, Volume: 23, Issue: 2		1978
Drug-induced hypertension: pathogenesis and management.
Drugs, Volume: 12, Issue: 3		1976
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]