Proteins > Sodium/bile acid cotransporter
Page last updated: 2024-08-07 23:24:06
Sodium/bile acid cotransporter
A hepatic sodium/bile acid cotransporter that is encoded in the genome of rat. [OMA:P26435, PRO:DNx]
Synonyms
Na(+)/bile acid cotransporter;
Na(+)/taurocholate transport protein;
Sodium/taurocholate cotransporting polypeptide;
Solute carrier family 10 member 1
Research
Bioassay Publications (5)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (7)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| taurocholic acid | Rattus norvegicus (Norway rat) | IC50 | 6.0000 | 1 | 1 |
Drugs with Other Measurements
Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump.American journal of physiology. Gastrointestinal and liver physiology, , Volume: 288, Issue:1, 2005
Bile acid conjugates of a nonsteroidal glucocorticoid receptor modulator.Bioorganic & medicinal chemistry letters, , Aug-16, Volume: 14, Issue:16, 2004
Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake.American journal of physiology. Gastrointestinal and liver physiology, , Volume: 285, Issue:5, 2003
Expression and characterization of a functional rat liver Na+ bile acid cotransport system in COS-7 cells.The American journal of physiology, , Volume: 266, Issue:3 Pt 1, 1994