Proteins > Proto-oncogene tyrosine-protein kinase LCK
Page last updated: 2024-08-07 12:52:45

Proto-oncogene tyrosine-protein kinase LCK

A tyrosine-protein kinase Lck that is encoded in the genome of mouse. [OMA:P06240, PRO:CNA]

Synonyms

EC 2.7.10.2;
Leukocyte C-terminal Src kinase;
LSK;
Lymphocyte cell-specific protein-tyrosine kinase;
p56-LCK

Research

Bioassay Publications (6)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Compounds (11)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
1-NA-PP1Mus musculus (house mouse)IC500.660011
ag 1879Mus musculus (house mouse)IC500.031011
zm 336372Mus musculus (house mouse)IC500.570011
repsoxMus musculus (house mouse)IC5016.000011
dasatinibMus musculus (house mouse)IC500.000411
dasatinibMus musculus (house mouse)Ki0.000111
1-tert-butyl-3-naphthalen-1-ylmethyl-1h-pyrazolo(3,4-d)pyrimidin-4-ylemineMus musculus (house mouse)IC500.460011
su 6656Mus musculus (house mouse)IC500.150011
N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamideMus musculus (house mouse)Ki5.400011
gw 2580Mus musculus (house mouse)IC5010.000011
cgp 57380Mus musculus (house mouse)IC502.500011

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
a 770041Mus musculus (house mouse)EC500.078011