Page last updated: 2024-08-07 17:27:24
Peptide deformylase
[no definition available]
Synonyms
Research
Bioassay Publications (6)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (3)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| indoleacetic acid | Escherichia coli | IC50 | 1,000.0000 | 1 | 1 |
| bb3497 | Escherichia coli | IC50 | 0.0180 | 2 | 3 |
| bb3497 | Escherichia coli | Ki | 0.0110 | 1 | 1 |
| actinonin | Escherichia coli | IC50 | 0.0520 | 3 | 3 |
Peptide deformylase inhibitors with activity against respiratory tract pathogens.Bioorganic & medicinal chemistry letters, , Jan-05, Volume: 14, Issue:1, 2004
Macrocyclic inhibitors for peptide deformylase: a structure-activity relationship study of the ring size.Journal of medicinal chemistry, , Sep-23, Volume: 47, Issue:20, 2004
Structure--activity relationships of the peptide deformylase inhibitor BB-3497: modification of the P2' and P3' side chains.Bioorganic & medicinal chemistry letters, , Aug-18, Volume: 13, Issue:16, 2003
Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase.Bioorganic & medicinal chemistry letters, , Aug-01, Volume: 21, Issue:15, 2011
Discovery and refinement of a new structural class of potent peptide deformylase inhibitors.Journal of medicinal chemistry, , Jan-11, Volume: 50, Issue:1, 2007
Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.Journal of medicinal chemistry, , Jun-15, Volume: 43, Issue:12, 2000