A chaperonin GroEL that is encoded in the genome of Escherichia coli K-12. [PRO:DNx, UniProtKB:P0A6F5]
GroEL protein;
Protein Cpn60
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 4-nonylphenol | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| albuterol | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| aurintricarboxylic acid | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| benzbromarone | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| bithionol | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| candesartan | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| dichlorophen | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| ethacrynic acid | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| harmalol | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| hexachlorophene | Escherichia coli K-12 | IC50 | 153.0000 | 1 | 1 |
| beta-lapachone | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| vitamin k 3 | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| mesalamine | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| primaquine | Escherichia coli K-12 | IC50 | 103.0000 | 1 | 1 |
| protoporphyrin ix | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| cetrimonium bromide | Escherichia coli K-12 | IC50 | 210.0000 | 1 | 1 |
| purpurin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| benzethonium chloride | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| evans blue | Escherichia coli K-12 | IC50 | 161.0000 | 1 | 1 |
| lithocholic acid | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| plumbagin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| gentian violet | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| erythromycin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| agaric acid | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| ethidium bromide | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| cetylpyridinium chloride | Escherichia coli K-12 | IC50 | 152.0000 | 1 | 1 |
| paclitaxel | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| closantel | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| adapalene | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| epigallocatechin gallate | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| sb 204070a | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| gossypol acetic acid | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| tretinoin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| arachidonic acid | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| riboflavin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 4'-methoxychalcone | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| curcumin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| gossypetin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| vitamin d 2 | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| cholecalciferol | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| morin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 4-hydroxychalcone | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 4'-hydroxychalcone | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| phenoxybenzamine hydrochloride | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| nalbuphine | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 22,23-dihydroavermectin b(1)a | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| avermectin b(1)a | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| erythrosine | Escherichia coli K-12 | IC50 | 222.0000 | 1 | 1 |
| tannins | Escherichia coli K-12 | IC50 | 137.0000 | 1 | 1 |
| 6-o-palmitoylascorbic acid | Escherichia coli K-12 | IC50 | 177.0000 | 1 | 1 |
| hematein | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |