Page last updated: 2024-11-08

bakkenolide a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

bakkenolide A: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID442173
CHEBI ID2984
SCHEMBL ID20225099
MeSH IDM0066155

Synonyms (31)

Synonym
fukinanolide
nsc-292655
fukinanolid
bakkenolid a
C09350
19906-72-0
bakkenolide a
(2r,3ar,7s,7ar)-7,7a-dimethyl-4'-methylidenespiro[3,3a,4,5,6,7-hexahydro-1h-indene-2,3'-oxolane]-2'-one
spiro(furan-3(2h),2'-indan)-2-one, 3'a,4,4',5,5',6',7',7'abeta-octahydro-3'abeta,4'beta-dimethyl-4-methylene-, (2'r)-
spiro(furan-3(2h),2'-(2h)inden)-2-one, decahydro-3'a,4'-dimethyl-4-methylene-, (2'r-(2'alpha,3'aalpha,4'alpha,7'aalpha))-
nsc 292655
(+)-bakkenolide a
t86zpp5fmq ,
unii-t86zpp5fmq
S9554
bakkenolide a, (+)-
spiro(furan-3(2h),2'-(2h)inden)-2-one, decahydro-3'a,4'-dimethyl-4-methylene-, (2'r,3'ar,4's,7'ar)-
spiro(furan-3(2h),2'-(2h)inden)-2-one, decahydro-3'a,4'-dimethyl-4-methylene-, (2'r-(2'.alpha.,3'a.alpha.,4'.alpha.,7'a.alpha.))-
spiro(furan-3(2h),2'-indan)-2-one, 3'a,4,4',5,5',6',7',7'a.beta.-octahydro-3'a.beta.,4'.beta.-dimethyl-4-methylene-, (2'r)-
CHEBI:2984
( )-bakkenolide a
DTXSID20173684 ,
SCHEMBL20225099
HY-N6017
FS-9836
bakkenolide
mfcd10566620
Q27105910
CS-0032181
AKOS040750440
dtxcid7096175

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" Based on the results, the oral bioavailability of BA in rats at 20 mg/kg is 15."( Determination of bakkenolide A in rat plasma using liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study.
Bao, Y; Chen, F; Chen, X; Dai, D; Li, J; Liu, S; Pei, L; Zheng, J, 2012
)
0.72
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
sesquiterpenoidAny terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's7 (63.64)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.35

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.35 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index5.20 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (20.35)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]