Proteins > Zinc finger protein mex-5
Page last updated: 2024-08-07 17:32:02

Zinc finger protein mex-5

A protein that is a translation product of the mex-5 gene in worm. [PRO:DNx, UniProtKB:Q9XUB2]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (137)

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
3,4-dihydroxyphenylacetic acidCaenorhabditis elegansEC5028.895010
6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diolCaenorhabditis elegansEC503.293010
hexachloropheneCaenorhabditis elegansEC5019.095010
masoprocolCaenorhabditis elegansEC508.755010
protoporphyrin ixCaenorhabditis elegansEC508.887010
methylene blueCaenorhabditis elegansEC50113.886010
quinophthaloneCaenorhabditis elegansEC50300.000010
yohimbineCaenorhabditis elegansEC50103.486010
rheinCaenorhabditis elegansEC5021.569010
neutral red baseCaenorhabditis elegansEC5014.254010
malononitrile dimerCaenorhabditis elegansEC50168.908010
lysergolCaenorhabditis elegansEC5053.186010
isoetharine mesylateCaenorhabditis elegansEC50125.376010
benserazide hydrochlorideCaenorhabditis elegansEC500.112010
epigallocatechin gallateCaenorhabditis elegansEC500.727010
dimidium bromideCaenorhabditis elegansEC505.363010
methyl fluorone blackCaenorhabditis elegansEC500.082010
agroclavineCaenorhabditis elegansEC508.672010
2,4,6-tripyridyl-s-triazineCaenorhabditis elegansEC5054.575010
oxoglaucineCaenorhabditis elegansEC500.834010
paxillineCaenorhabditis elegansEC5012.272010
pyrophenCaenorhabditis elegansEC5027.938010
sk&f-38393Caenorhabditis elegansEC5023.990010
sb 216763Caenorhabditis elegansEC5021.547010
4-(2-methyl-5-phenyl-1-pyrrolyl)benzoic acidCaenorhabditis elegansEC50300.000010
2-carbazol-9-ylbenzoic acidCaenorhabditis elegansEC50300.000010
(R)-RoemerineCaenorhabditis elegansEC5021.456010
oxopurpureineCaenorhabditis elegansEC504.831010
3,6-bis(2-pyridyl)-1,2,4,5-tetrazineCaenorhabditis elegansEC5049.783010
18-Hydroxy-11,17-dimethoxyyohimban-16-carboxylic acidCaenorhabditis elegansEC50300.000010
(R)-norlaudanosolineCaenorhabditis elegansEC505.431010
resveratrolCaenorhabditis elegansEC50163.131010
2-phenoxy-N-(2-pyridinyl)butanamideCaenorhabditis elegansEC50300.000010
2-(N-[2-(1-benzotriazolyl)-1-oxoethyl]-4-methoxyanilino)-N-(2-methylbutan-2-yl)-2-(1-methyl-2-pyrrolyl)acetamideCaenorhabditis elegansEC50300.000010
6-hydroxy-1-(3-hydroxypropyl)-4-methyl-2-oxo-5-(1-piperidinylmethyl)-3-pyridinecarbonitrileCaenorhabditis elegansEC50300.000010
2-cyano-N-(3-methoxypropyl)-2-[3-(1-pyrrolidinyl)-2-quinoxalinyl]acetamideCaenorhabditis elegansEC50300.000010
N-ethyl-2-imino-10-methyl-1-[(4-methylphenyl)methyl]-5-oxo-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamideCaenorhabditis elegansEC5045.514010
7-(diethylamino)-2-oxo-1-benzopyran-3-carbonitrileCaenorhabditis elegansEC5062.966010
6-amino-5-(methylamino)-1-(phenylmethyl)pyrimidine-2,4-dioneCaenorhabditis elegansEC5092.094010
N'-[(4-chlorophenyl)-oxomethyl]-2-pyrazinecarbohydrazideCaenorhabditis elegansEC5012.410010
2-bromo-N-(3-methoxyphenyl)benzamideCaenorhabditis elegansEC50300.000010
2-phenyl-3-imidazo[1,2-a]pyridinecarboxaldehydeCaenorhabditis elegansEC50300.000010
1-[[(1,5-dimethyl-3-pyrazolyl)-oxomethyl]amino]-3-(2-methoxyphenyl)thioureaCaenorhabditis elegansEC5058.442010
3-(3-formyl-2,5-dimethyl-1-pyrrolyl)-4-methylbenzoic acid methyl esterCaenorhabditis elegansEC50300.000010
umi-77Caenorhabditis elegansEC508.174010
7-anilino-1-(4-methylphenyl)-5-oxo-[1,2,4]triazolo[4,3-a]pyrimidine-3-carboxylic acid ethyl esterCaenorhabditis elegansEC50300.000010
2-imino-10-methyl-N-[2-(4-morpholinyl)ethyl]-5-oxo-1-(3-pyridinylmethyl)-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamideCaenorhabditis elegansEC5087.175010
2-[2,5-dimethyl-3-[(2,4,6-trioxo-1,3-diazinan-5-ylidene)methyl]-1-pyrrolyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl esterCaenorhabditis elegansEC50300.000010
2-[[3-(3,4-dimethoxyphenyl)-2-oxo-1-benzopyran-7-yl]oxy]acetamideCaenorhabditis elegansEC50300.000010
3-amino-8-methyl-N-[4-(4-morpholinyl)phenyl]-2-thieno[2,3-b]quinolinecarboxamideCaenorhabditis elegansEC50300.000010
2-(4-chlorophenoxy)-4-(dimethylamino)-3-pyridinecarbonitrileCaenorhabditis elegansEC50300.000010
1,4-benzoquinone guanylhydrazone thiosemicarbazoneCaenorhabditis elegansEC509.727010
5-bromo-N-(2-fluorophenyl)-6-oxo-3-pyrancarboxamideCaenorhabditis elegansEC50300.000010
1-[2-[(2-methylphenyl)methylthio]ethyl]-3-phenylthioureaCaenorhabditis elegansEC50300.000010
2,8-dimercapto-6-hydroxypurineCaenorhabditis elegansEC508.295010
1,3-benzothiazole-6-carboxylic acid [2-(2-furanyl)-2-oxoethyl] esterCaenorhabditis elegansEC50300.000010
5-(methoxymethyl)-2-thiophen-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-oneCaenorhabditis elegansEC50300.000010
N'-benzoyl-2-(3-pyridinyl)-4-thiazolecarbohydrazideCaenorhabditis elegansEC50300.000010
2-amino-4-(4,5-dimethoxy-2-nitrophenyl)-7,7-dimethyl-5-oxo-6,8-dihydro-4H-1-benzopyran-3-carbonitrileCaenorhabditis elegansEC5023.006010
2-amino-7-methyl-5-oxo-4-(2,3,4-trimethoxyphenyl)-4,6,7,8-tetrahydro-1-benzopyran-3-carbonitrileCaenorhabditis elegansEC50300.000010
2-amino-7-methyl-5-oxo-4-(2,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydro-1-benzopyran-3-carbonitrileCaenorhabditis elegansEC50300.000010
1-hexadecyl-3-methylimidazolium bromideCaenorhabditis elegansEC50300.000010
2-cyano-N-(phenylmethyl)-2-[3-(1-pyrrolidinyl)-2-quinoxalinyl]acetamideCaenorhabditis elegansEC50300.000010
2-benzoyl-N-(6-methoxy-3-pyridinyl)-3,4-dihydro-1H-isoquinoline-3-carboxamideCaenorhabditis elegansEC50300.000010
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolineCaenorhabditis elegansEC50300.000010
4-(6-bromo-1,3-benzodioxol-5-yl)-7,9-dimethyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolineCaenorhabditis elegansEC50300.000010
1-[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]ethanoneCaenorhabditis elegansEC50300.000010
N-[[[(2-hydroxyphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-2-nitrobenzamideCaenorhabditis elegansEC5032.190010
2-imino-1-[(4-methylphenyl)methyl]-5-oxo-N-(2-oxolanylmethyl)-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarboxamideCaenorhabditis elegansEC50300.000010
6-amino-2-ethyl-8-[2-(trifluoromethyl)phenyl]-1,6,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrileCaenorhabditis elegansEC50300.000010
2-(3-ethoxypropylamino)-8-methyl-5-oxo-N-(2-oxolanylmethyl)-3-dipyrido[1,2-pyrimidinecarboxamideCaenorhabditis elegansEC50300.000010
5-[(4-fluorophenyl)methylsulfonylmethyl]-N-(2-oxolanylmethyl)-2-furancarboxamideCaenorhabditis elegansEC50300.000010
4-[[2-[[cyclohexyl(oxo)methyl]amino]-1-oxo-3-phenylpropyl]amino]-1-piperidinecarboxylic acid ethyl esterCaenorhabditis elegansEC50300.000010
4-morpholinecarboxylic acid [4-(2-amino-3-cyano-5-oxo-4,6,7,8-tetrahydro-1-benzopyran-4-yl)-2,6-dimethoxyphenyl] esterCaenorhabditis elegansEC50300.000010
4-[3-(1,3-diphenyl-4-pyrazolyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-4-oxobutanoic acidCaenorhabditis elegansEC50300.000010
6-(5,6-Dihydroxy-4-oxo-2-phenylchromen-7-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acidCaenorhabditis elegansEC5011.889010
4-(3,5-dimethyl-1-piperidinyl)-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-4-oxobutanamideCaenorhabditis elegansEC50300.000010
N,6-dimethyl-2-[[[4-[(2-methyl-1-piperidinyl)sulfonyl]phenyl]-oxomethyl]amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamideCaenorhabditis elegansEC50300.000010
5-(3,4-dimethoxyphenyl)-3-(2-furanylmethyl)-4-imino-5H-[1]benzopyrano[2,3-d]pyrimidin-8-olCaenorhabditis elegansEC50300.000010
luteolinCaenorhabditis elegansEC5031.000010
methysergide maleateCaenorhabditis elegansEC5020.045010
myricitrinCaenorhabditis elegansEC5014.047010
rosmarinic acidCaenorhabditis elegansEC508.751010
4-[(3aR,4S,9bS)-8-[(4-methoxyphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acidCaenorhabditis elegansEC507.878010
semaxinibCaenorhabditis elegansEC50300.000010
2-(4-(dimethylamino)styryl)benzothiazoleCaenorhabditis elegansEC50300.000010
1,5-dioxo-2,4-dihydropyrrolo[1,2-a]quinazoline-3-carboxylic acid ethyl esterCaenorhabditis elegansEC5038.823010
quinaldine redCaenorhabditis elegansEC50300.000010
2',3,4-trihydroxychalconeCaenorhabditis elegansEC5042.270010
3-amino-5-(4-bromophenyl)-4-pyridazinecarbonitrileCaenorhabditis elegansEC50300.000010
cefdinirCaenorhabditis elegansEC5033.257010
altenusinCaenorhabditis elegansEC50300.000010
1-(3,4-dimethylphenyl)-2,5-dioxo-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarbonitrileCaenorhabditis elegansEC5055.783010
mdl 105725Caenorhabditis elegansEC5013.667010
3-amino-2-cyano-5-(3-methoxyphenyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid methyl esterCaenorhabditis elegansEC50300.000010
2-hydroxyapomorphine, (r)-isomerCaenorhabditis elegansEC503.173010
N-butyl-N-methyl-4-[(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazo]-4-oxobutanamideCaenorhabditis elegansEC505.369010
[5-Chloranyl-3-[(1E,3E)-3,5-dimethylhepta-1,3-dienyl]-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] ethanoateCaenorhabditis elegansEC50300.000010
N-[3-(diethylamino)propyl]-4-[(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazo]-4-oxobutanamideCaenorhabditis elegansEC500.930010
violaceol IICaenorhabditis elegansEC5012.891010
2-(2-acetyl-3,5-dihydroxyphenyl)acetic acidCaenorhabditis elegansEC50190.024010
cyclopenolCaenorhabditis elegansEC5035.084010
N-[5-[methyl-(3-methylphenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl]-2-furancarboxamideCaenorhabditis elegansEC50300.000010
N-[1-(3-fluorophenyl)-6,6-dimethyl-5,7-dihydro-4H-indazol-4-yl]-2-(2-pyridinylthio)acetamideCaenorhabditis elegansEC50150.000010
3-[[1-[1-(methylthio)propan-2-yl]-4-piperidinyl]oxy]-N-(2-pyridinylmethyl)benzamideCaenorhabditis elegansEC5075.422010
2-(4-morpholinyl)-N'-[(2-nitrophenyl)-oxomethyl]-4-thiazolecarbohydrazideCaenorhabditis elegansEC500.731010
2-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-1H-quinazolin-4-oneCaenorhabditis elegansEC50300.000010

Drugs with Other Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
5,8,11,14-eicosatetraynoic acidCaenorhabditis elegansAC506.712010
methyl gallateCaenorhabditis elegansAC5025.430010
s-2678Caenorhabditis elegansAC5033.400010
4-(2-thiazolylazo)resorcinolCaenorhabditis elegansAC5038.260010
sch 45752Caenorhabditis elegansAC502.069010
raubasineCaenorhabditis elegansAC504.211010
nsc-260594Caenorhabditis elegansAC506.782010
8-(1H-indol-3-ylmethylidene)-6,10-dioxaspiro[4.5]decane-7,9-dioneCaenorhabditis elegansAC50106.700010
2-[[[(6-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]amino]-5-phenyl-3-thiophenecarboxylic acid ethyl esterCaenorhabditis elegansAC5013.093010
[3-amino-6-thiophen-2-yl-4-(trifluoromethyl)-2-thieno[2,3-b]pyridinyl]-cyclopropylmethanoneCaenorhabditis elegansAC50380.000010
5-[2-methyl-1-(phenylmethyl)-6-(trifluoromethyl)-4-pyridinylidene]-2-sulfanylidene-1,3-diazinane-4,6-dioneCaenorhabditis elegansAC5061.380010
1-[1-ethyl-6-methyl-4-(4-phenyl-1-piperazinyl)-2-sulfanylidene-5-pyrimidinyl]ethanoneCaenorhabditis elegansAC50380.000010
4-(4-methyl-1-piperazinyl)-2,6-diphenyl-5-pyrimidinecarbonitrileCaenorhabditis elegansAC50380.000010
9-methoxy-6-[(4-methoxyphenyl)methyl]indolo[3,2-b]quinoxalineCaenorhabditis elegansAC5022.890010
3-amino-N-(2-fluorophenyl)-6-(3-pyridinyl)-2-thieno[2,3-b]pyridinecarboxamideCaenorhabditis elegansAC5087.820010
6-amino-5-cyano-4-(2,4-dimethoxyphenyl)-2-(2-ethoxy-2-oxoethyl)-4H-pyran-3-carboxylic acid ethyl esterCaenorhabditis elegansAC5017.533010
LSM-16248Caenorhabditis elegansAC501.008010
N'-[(2-nitrophenyl)-oxomethyl]-2-pyridinecarbohydrazideCaenorhabditis elegansAC500.929010
N1',N6'-bis[(5-methyl-1H-pyrazol-3-yl)-oxomethyl]hexanedihydrazideCaenorhabditis elegansAC500.300010
4-chloro-N-(2-methoxy-1-phenazinyl)benzamideCaenorhabditis elegansAC5049.240010
2-[[3-(3-oxo-1,2-benzothiazol-2-yl)phenyl]sulfonylamino]benzoic acidCaenorhabditis elegansAC507.895010
5-bromo-N-[2-(2-methyl-1-indolyl)ethyl]-2-furancarboxamideCaenorhabditis elegansAC50380.000010
N-(6-methoxy-3-pyridinyl)-7-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamideCaenorhabditis elegansAC5015.444010
R-(-)-actinodaphnineCaenorhabditis elegansAC5048.480010
4-[(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazo]-4-oxo-N-propan-2-ylbutanamideCaenorhabditis elegansAC500.300010
ophiocarpineCaenorhabditis elegansAC5079.330010
4'-epichaetoviridin ACaenorhabditis elegansAC5042.997010
methacycline monohydrochlorideCaenorhabditis elegansAC5017.690010
mysteclin fCaenorhabditis elegansAC50380.000010
galloflavinCaenorhabditis elegansAC502.998010