A myosin light chain kinase, smooth muscle that is encoded in the genome of chicken. [PANTHER:PTHR22964:SF3, PRO:DNx]
MLCK;
EC 2.7.11.18;
Telokin
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| n-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide | Gallus gallus (chicken) | Ki | 68.0000 | 1 | 1 |
| wortmannin | Gallus gallus (chicken) | IC50 | 0.2600 | 1 | 1 |
| h 89 | Gallus gallus (chicken) | Ki | 28.3000 | 1 | 1 |
| sf 2370 | Gallus gallus (chicken) | IC50 | 0.0000 | 1 | 1 |
| kn 93 | Gallus gallus (chicken) | IC50 | 9.8000 | 1 | 1 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| sb 202190 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| imatinib | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| staurosporine | Gallus gallus (chicken) | Kd | 0.1400 | 1 | 1 |
| gefitinib | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| vatalanib | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| ruboxistaurin | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| canertinib | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| birb 796 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| cyc 202 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| sb 203580 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| erlotinib | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| lapatinib | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| sorafenib | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| bms 387032 | Gallus gallus (chicken) | Kd | 1.7000 | 1 | 1 |
| tandutinib | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| vx-745 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| dasatinib | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| zd 6474 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| alvocidib | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| su 11248 | Gallus gallus (chicken) | Kd | 0.0230 | 1 | 1 |
| jnj-7706621 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| vx680 | Gallus gallus (chicken) | Kd | 0.0150 | 1 | 1 |
| ekb 569 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| midostaurin | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| cp 724714 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| pi103 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| tofacitinib | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| pazopanib | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| su 14813 | Gallus gallus (chicken) | Kd | 0.0420 | 1 | 1 |
| nvp-ast487 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| abt 869 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| gw 2580 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| chir-265 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| motesanib | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| mln8054 | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| azd 1152-hqpa | Gallus gallus (chicken) | Kd | 10.0000 | 1 | 1 |
| chir 258 | Gallus gallus (chicken) | Kd | 0.0020 | 1 | 1 |